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6. Clinical significance of MRI-measured olfactory bulb height as an imaging biomarker of idiopathic Parkinson's disease.

Author

Park, Sohyun, Lee, Jungbin, Kim, Jung Youn, Park, Jeong-Ho, Lee, Ji Eun, Park, Sang Ik, and Yim, Younghee

Abstract

Objectives: This study aimed to determine whether the olfactory bulb height (OBH) measured using magnetic resonance imaging (MRI) has clinical utility as an imaging biomarker in the evaluation of patients with idiopathic Parkinson's disease (iPD) through its correlation with movement impairment. Methods: This retrospective study included cognitively intact patients with suspected parkinsonism. All participants underwent T2-weighted imaging to measure OBH. Logistic regression was used to determine whether OBH was an independent risk factor for distinguishing iPD patients from disease controls, and its relation with clinical parameters related to motor impairment, including clinical laterality, modified Hoehn and Yahr (HY) stage, and Unified Parkinson's Disease Rating Scale (UPDRS) III score, was investigated. Results: Based on the final clinical diagnosis, 79 patients with iPD and 16 disease controls were included. The mean OBH was significantly smaller in iPD than in disease controls (p < 0.0001). OBH was a significant independent predictor of iPD, with a cutoff of 1.52 mm. In the comparison among the ipsilateral, contralateral side of iPD with clinical laterality, and disease control group, the OBH of the disease control group was significantly larger than both the ipsilateral and contralateral sides (P < 0.05). However, there was no significant difference in OBH between the ipsilateral and contralateral sides (p > 0.05). OBH according to HY stage was significantly smaller in HY stage 2–3 groups than in the disease control group (p < 0.001). The correlation analysis between UPDRS III and OBH showed a mild negative correlation (r = -0.32, p = 0.013). Conclusions: MRI-measured OBH is decreased in iPD regardless of age and sex and may be correlated with the progression of motor symptoms in the iPD. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Low-dose CT for the diagnosis of appendicitis in adolescents and young adults (LOCAT): a pragmatic, multicentre, randomised controlled non-inferiority trial

Author

Kim, Hyuk Jung, Jeon, Byeong Geon, Hong, Chong Kun, Kwon, Kye Won, Han, Seung Bong, Paik, Soya, Jang, Suk Ki, Ha, Young Rock, Kim, Young Sik, Lee, Min Hee, Yi, Boem Ha, Shin, Eung Jin, Lee, Hae Kyung, Kim, Hee Kyung, Kim, Ho Jung, Choi, Jae Hyung, Cho, Young Soon, Kim, Min-Jeong, Kim, Dong Kyu, Choe, Ji-Young, Min, Kyueng-Whan, Lim, Man Sup, Ha, Sang Ook, Lim, Sang Woo, Sohn, Youdong, Lee, Young Hwan, Park, Ji Hoon, Gu, Bon Seung, Lee, Hye Seung, Lee, Jae Hyuk, Sim, Ji Ye, Kim, Joonghee, Lee, Kyoung Ho, Kim, Kyuseok, Ahn, Soyeon, Kang, Sung-Bum, Lee, Yoon Jin, Jo, You Hwan, Kim, Young Hoon, Ko, Yousun, Choi, Seung Joon, Song, Bohyung, Goh, Byung Ho, Lim, Chaesuk, Kim, Chang Rae, Seo, Cho Rong, Kim, Eunbaeck, Han, Gio, Woo, Jae-Hyug, Kim, Jinhyun, Min, Kyoungjin, Lee, Min-A, Jeong, Min Ju, Lee, Min Kyoung, Lim, Yong Su, Shim, Young Sup, Park, Sung Bin, Kim, Chan Woong, Lee, Dong Hoon, Lee, Seung Eun, Kim, Sung Eun, Choi, Yoo Shin, Rha, Sung Eun, Jung, Eun Sun, Na, Gun Hyung, Kim, Han Joon, Yoo, Han Mo, Chang, Hye Kyung, Choi, Joon Il, Park, Kyu Nam, Park, Michael Yong, Choi, Moon Hyung, Oh, Sang Hoon, Jung, Seung Eun, Lee, Sohee, Im, Soo Ah, Kim, Soo Hyun, Oh, Soon Nam, Hong, Tae Ho, Kang, Won-Kyung, Lee, Young Joon, Kang, Dong Baek, Han, Hyun Soo, Choi, Jeong Woo, Yoon, Ki-Jung, Hwang, Yong, Hong, Seong Sook, Hwang, Eui Sung, Chung, Heajin, Jang, Hye Young, Hwang, Jiyoung, Park, Jun Bum, Hur, Kyung Yul, Jeen, Yoon Mi, Lee, Young Joo, Cho, Young Shin, Cho, Han Jin, Choi, Inyoung, Park, Jong Hak, Kim, Jooyeong, Yeom, Suk Keu, Moon, Sung Woo, Kim, Mi Sung, Shin, Dong Hyuk, Kwon, Heon-Ju, Choi, Pil Cho, Han, Sang Kuk, Woo, Ji Young, Kang, Gu Hyun, Kim, Han Myun, Choi, Hyun Young, Yang, Ik, Jang, Jae Ho, Kim, Jeong Won, Yoon, Sang Nam, Kim, Won Hee, Jang, Yong Soo, Park, Mi-Suk, Park, In Cheol, Lee, Jae Gil, Kim, Min Joung, Chung, Yong Eun, Lee, Jongmee, Kim, Baek-Hui, Lee, Chang Hee, Kim, Jung-Youn, Kang, Sanghee, Choi, Sung-Hyuk, Park, Yang Shin, Cho, Seong Whi, Park, Chan Woo, Chae, Gi Bong, Ohk, Taek Guen, Jeon, Yong-Hwan, Hong, Nurhee, Wi, Dae Han, Lee, Jun Hee, Kwon, Jung Nam, Lee, Seok Youn, Han, Weon-Cheol, Song, Young Cheol, Kim, Mi Jeong, Kwon, Jung Hyeok, Beak, Seoung Kyu, Kim, Sung Jin, Choi, Woo Ik, Kang, Yu Na, Shin, Cheong-Il, Lee, Dong Ho, Kang, Gyeong Hoon, Joo, Ijin, Yoon, Jeong Hee, Park, Ji Won, Park, Kyu Joo, Shin, Sang Do, Ryoo, Seung-Bum, Jeong, Seung-Yong, Ahn, Su Joa, Kim, Tae Han, Chang, Won, Kwon, Yoon-Hye, Shin, Sang Soo, Kim, Hee Joon, Kim, Ho Goon, Cho, Yong Soo, Choi, Yoo Duk, Kim, Bong Soo, Hyun, Chang Lim, Choi, Guk Myung, Jeong, In Ho, Kang, Kyeong Won, Kim, Seung Hyoung, Kim, Woo Jeong, Kang, Young Joon, and Kim, Kwang Pyo

Published
2017
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36. Association of Cerebral White Matter Hyperintensities with Coronary Artery Calcium in a Healthy Population: A Cross-Sectional Study

Author

Kim, Jung Youn

Subjects
Neuroradiology brain, Arteriosclerosis, Epidemiology, MR-Angiography, Hypertension, Screening, CNS, MR, Diagnostic procedure
Abstract

Learning objectives Background Findings and procedure details Conclusion Personal information and conflict of interest References, Learning objectives: White matter hyperintensity (WMH) is a commonly encountered on T2-weighted and fluid attenatuated inversion recovery (FLAIR) imaging of brain magnetic resonance imaging (MRI). The exact pathophysiologic mechanisms of WMH are unclear, but it has been...

Published
2023
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50. Successful resuscitation of refractory ventricular fibrillation with double sequence defibrillation

Author

Park, SungJoon, Kim, Jung-Youn, Cho, Young-Duck, Lee, Eusun, Shim, Bosun, and Yoon, Young-Hoon

Subjects
survival rate, medicine.medical_specialty, Defibrillation, medicine.medical_treatment, CPR/Resuscitation, Case Report, Critical Care and Intensive Care Medicine, Critical Care Nursing, Chest pain, Internal medicine, defibrillators, medicine, Survival rate, medicine.diagnostic_test, business.industry, Mortality rate, Advanced cardiac life support, lcsh:Medical emergencies. Critical care. Intensive care. First aid, lcsh:RC86-88.9, Emergency department, ventricular fibrillation, medicine.disease, Ventricular fibrillation, Cardiology, advanced cardiac life support, medicine.symptom, business, Electrocardiography
Abstract

In cardiac arrest, if the initial rhythm is ventricular fibrillation (VF) or pulseless ventricular tachycardia, the survival rates are high and good neurologic outcomes are expected. However, the mortality rate increases when refractory ventricular fibrillation (RVF) occurs. We report a case of RVF that was successfully resuscitated with double sequence defibrillation (DSD). A 51-year-old man visited the emergency department with chest pain. The initial electrocardiography showed markedly elevated ST-segment on V1–V5 leads, and VF arrest occurred. Although 10 defibrillations were administered over 20 minutes, there was no response. Two rounds of DSD were performed by placing additional pads on the patient’s anterior-posterior areas and sequentially applying the maximum energy setting. The patient returned to spontaneous circulation and was discharged with cerebral performance category 1 after 14 days of hospital admission. Therefore, DSD could be an option for treatment and termination of RVF.

Published
2021

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