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2. Multi-Convergence-Angle Ptychography with Simultaneous Strong Contrast and High Resolution

Author

Mao, Wei, Zhang, Weiyang, Huang, Chen, Zhou, Liqi, Kim, Judy. S., Gao, Si, Lei, Yu, Wu, Xiaopeng, Hu, Yiming, Pei, Xudong, Fang, Weina, Liu, Xiaoguo, Song, Jingdong, Fan, Chunhai, Nie, Yuefeng, Kirkland, Angus. I., and Wang, Peng

Subjects
Physics - Optics, Condensed Matter - Materials Science, Physics - Biological Physics
Abstract

Advances in bioimaging methods and hardware facilities have revolutionised the determination of numerous biological structures at atomic or near-atomic resolution. Among these developments, electron ptychography has recently attracted considerable attention because of its superior resolution, remarkable sensitivity to light elements, and high electron dose efficiency. Here, we introduce an innovative approach called multi-convergence-angle (MCA) ptychography, which can simultaneously enhance both contrast and resolution with continuous information transfer across a wide spectrum of spatial frequency. Our work provides feasibility of future applications of MCA-ptychography in providing high-quality two-dimensional images as input to three-dimensional reconstruction methods, thereby facilitating more accurate determination of biological structures.

Published
2024

4. Cryo-Electron Ptychography: Applications and Potential in Biological Characterisation

Author

Huang, Chen, Kim, Judy S., and Kirkland, Angus I.

Subjects
Quantitative Biology - Quantitative Methods
Abstract

There is a clear need for developments in characterisation techniques that provide detailed information about structure-function relationships in biology. Using electron microscopy to achieve high resolution while maintaining a broad field of view remains a challenge, particularly for radiation sensitive specimens where the signal-to-noise ratio required to maintain structural integrity is limited by low electron fluence. In this review, we explore the potential of cryogenic electron ptychography as an alternative method for characterisation of biological systems under low fluence conditions. Using this method with increased information content from multiple sampled regions of interest, potentially allows 3D reconstruction with far fewer particles than required in conventional cryo-electron microscopy. This is important for achieving higher resolution for systems where distributions of homogeneous single particles are difficult to obtain. We discuss the progress, limitations and potential areas for future development of this approach for both single particle analysis and in applications to heterogeneous large objects.

Published
2023

6. List of contributors

Author

Mirshahi, Reza, primary, Fallon, Julia, additional, Acar, Burak, additional, Acharya, Isha, additional, Agarwal, Aniruddha, additional, Agrawal, Kushal, additional, Ahsanuddin, Sofia, additional, Alforja, Socorro, additional, Aljneibi, Shaikha, additional, Arévalo, J. Fernando, additional, Ayachit, Apoorva, additional, Ayachit, Guruprasad, additional, Baek, Jiwon, additional, Bandello, Francesco, additional, Baumal, Caroline R., additional, Bernal-Morales, Carolina, additional, Bertelli, Pietro M., additional, Bharath, Abhinaya, additional, Biswas, Jyotirmay, additional, Blindbæk, Søren Leer, additional, Bonhomme, Gabrielle, additional, Bonilla, Alan Chew, additional, Bonnin, Sophie, additional, Borrelli, Enrico, additional, Bousquet, Elodie, additional, Caranfa, Jonathan T., additional, Cassoux, Nathalie, additional, Chatziralli, Irini, additional, Checchin, Lisa, additional, Chhablani, Jay, additional, Chotcomwongse, Peranut, additional, Choudhry, Netan, additional, Chui, Toco, additional, Cruz-Pimentel, Miguel, additional, Eandi, Chiara M., additional, El Moussawi, Zeinab, additional, Errera, Marie-Helene, additional, Espejo-Arjona, Francisco, additional, Eyre, Jessica, additional, Falavarjani, Khalil Ghasemi, additional, Gallego-Pinazo, Roberto, additional, Gaudric, Alain, additional, Gonzalez, Monica P., additional, Grauslund, Jakob, additional, Guduric-Fuchs, Jasenka, additional, Guerra, Ricardo Leitão, additional, Gutiérrez-Bonet, Rosa, additional, Handa, Ashit, additional, Iovino, Claudio, additional, Jones, Anthony A., additional, Joshi, Shrinivas, additional, Kim, Judy E., additional, Kodjikian, Laurent, additional, Kulikov, Alexey N., additional, Labay-Tejado, Sara, additional, Ledesma-Gil, Gerardo, additional, Lippincott, John K., additional, Lois, Noemi, additional, Lupidi, Marco, additional, Mainster, Martin A., additional, Malaise, Denis, additional, Maltsev, Dmitrii S., additional, Mammo, Danny A., additional, Mangla, Rubble, additional, Mansour, Hana A., additional, Mansour, Ahmad M., additional, Mariotti, Cesare, additional, Matet, Alexandre, additional, Mathis, Thibaud, additional, Medina, Reinhold J., additional, Melo, Isabela Martins, additional, Menendez-Acebal, Covadonga, additional, Micevych, Paul S., additional, Montesel, Andrea, additional, Montolío-Marzo, Santiago, additional, Muni, Rajeev H., additional, Muñoz-Solano, Javier, additional, Muzi, Alessio, additional, Neto, Laurentino Biccas, additional, Ong, Joshua, additional, Ong, Sally S., additional, Orr, Samantha, additional, Özdek, Şengül, additional, Pacques, Michel, additional, Pappelis, Konstantinos, additional, Pathak, Varun, additional, Pattathil, Niveditha, additional, Pearce, Thomas M., additional, Penha, Fernando M., additional, Pichi, Francesco, additional, Poireir, Matthieu, additional, Prabhu, Vishma, additional, Querques, Giuseppe, additional, Rachitskaya, Aleksandra V., additional, Rahimi Ardali, Kimia, additional, Raval, Vishal, additional, Raval, Nilesh, additional, Reddy, Nikitha Gurram, additional, Reibaldi, Michele, additional, Reid, Emma, additional, Ricardi, Federico, additional, Rosen, Richard, additional, Rosier, Laurence, additional, Ruamviboonsuk, Paisan, additional, Ruiz-Medrano, Jorge, additional, Ruiz-Moreno, José M., additional, Sacconi, Riccardo, additional, Santina, Ahmad, additional, Sarraf, David, additional, Schwartz, Carol E., additional, Scott, Adrienne W., additional, Shaheen, Abdulla R., additional, Silpa-archa, Sukhum, additional, Singh, Sumit Randhir, additional, Sivalingam, Meera D., additional, Sridhar, Jayanth, additional, Stewart, Jay M., additional, Stitt, Alan W., additional, Tadarati, Mongkol, additional, Thariat, Juliette, additional, Turgut, Burak, additional, Venkatesh, Ramesh, additional, Vergmann, Anna Stage, additional, Vidal-Oliver, Lourdes, additional, Vujosevic, Stela, additional, Wakabayashi, Taku, additional, Wang, Kristine, additional, Wu, Lihteh, additional, Wu, Andres, additional, Wu, Max, additional, Yonekawa, Yoshihiro, additional, Zarnegar, Arman, additional, Zarranz-Ventura, Javier, additional, Zeydanli, Ece Ozdemir, additional, Zhang, Xinyuan, additional, and Zucchiatti, Ilaria, additional

Published
2024
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7. Role of the Triplet State and Protein Dynamics in the Formation and Stability of the Tryptophan Radical in an Apoazurin Mutant

Author

López-Peña, Ignacio, Lee, Christopher T, Rivera, Joel J, and Kim, Judy E

Subjects
Chemical Sciences, Physical Chemistry, Theoretical and Computational Chemistry, Apoproteins, Azurin, Kinetics, Tryptophan, Physical Sciences, Engineering, Chemical sciences, Physical sciences
Abstract

The protein, azurin, has enabled the study of the tryptophan radical. Upon UV excitation of tyrosine-deficient apoazurin and in the presence of a Co(III) electron acceptor, the neutral radical (W48•) is formed. The lifetime of W48• in apoazurin is 41 s, which is shorter than the lifetime of several hours in Zn-substituted azurin. Molecular dynamics simulations revealed enhanced fluctuations of apoazurin which likely destabilize W48•. The photophysics of W48 was investigated to probe the precursor state for ET. The phosphorescence intensity was eliminated in the presence of an electron acceptor while the fluorescence was unchanged; this quenching of the phosphorescence is attributed to ET. The kinetics associated with W48• were examined with a model that incorporates intersystem crossing, ET, deprotonation, and decay of the cation radical. The estimated rate constants for ET (6 × 106 s-1) and deprotonation (3 × 105 s-1) are in agreement with a photoinduced mechanism where W48• is derived from the triplet state. The triplet as the precursor state for ET was supported by photolysis of apoazurin with 280 nm in the absence and presence of triplet-absorbing 405 nm light. Absorption bands from the neutral radical were observed only in the presence of blue light.

Published
2022

9. SUPRACHOROIDAL SPACE INJECTION TECHNIQUE: Expert Panel Guidance

Author

Wykoff, Charles C., Avery, Robert L., Barakat, Mark R., Boyer, David S., Brown, David M., Brucker, Alexander J., Cunningham, Emmett T., Jr, Heier, Jeffrey S., Holekamp, Nancy M., Kaiser, Peter K., Khanani, Arshad M., Kim, Judy E., Demirci, Hakan, Regillo, Carl D., Yiu, Glenn C., and Ciulla, Thomas A.

Published
2024
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10. Demographic and Metabolic Risk Factors Associated with Development of Diabetic Macular Edema among Persons with Diabetes Mellitus

Author

Pershing, Suzann, Wang, Sophia Y., Amin, Sejal, Edwards, Paul A., Srikumaran, Divya, Woreta, Fasika, Schultz, Jeffrey S., Shrivastava, Anurag, Ahmad, Baseer, Kim, Judy E., Bryar, Paul, French, Dustin, Vanderbeek, Brian L., Lynch, Anne M., Patnaik, Jenna, Munir, Saleha, Munir, Wuqaas, Stein, Joshua D., DeLott, Lindsey, Stagg, Brian C., Wirostko, Barbara, McMillian, Brian, Sheybani, Arsham, Sieck, Erin, Deiner, Michael, Sun, Cathy, Sarrapour, Soshian, Liu, Ji, Feldman, Robert, Haliyur, Rachana, Marwah, Shikha, Mittal, Shreya, and Shah, Anjali R.

Published
2024
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12. Prediction Models for Glaucoma in a Multicenter Electronic Health Records Consortium: The Sight Outcomes Research Collaborative

Author

Amin, Sejal, Edwards, Paul A., Srikumaran, Divya, Woreta, Fasika, Schultz, Jeffrey S., Shrivastava, Anurag, Ahmad, Baseer, Kim, Judy, Bryar, Paul, French, Dustin, Vanderbeek, Brian L., Pershing, Suzann, Wang, Sophia Y., Lynch, Anne M., Patnaik, Jenna, Munir, Saleha, Munir, Wuqaas, Stein, Joshua, DeLott, Lindsey, Stagg, Brian C., Wirostko, Barbara, McMillian, Brian, Sheybani, Arsham, Ravindranath, Rohith, and Stein, Joshua D.

Published
2024
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15. A Randomized Trial of Photobiomodulation Therapy for Center-Involved Diabetic Macular Edema with Good Visual Acuity (Protocol AE)

Author

Kim, Judy E, Glassman, Adam R, Josic, Kristin, Melia, Michele, Aiello, Lloyd P, Baker, Carl, Eells, Janis T, Jampol, Lee M, Kern, Timothy S, Marcus, Dennis, Salehi-Had, Hani, Shah, Sandeep N, Martin, Daniel F, Stockdale, Cynthia R, Sun, Jennifer K, and Network, DRCR Retina

Subjects
Biomedical and Clinical Sciences, Ophthalmology and Optometry, Neurosciences, Eye Disease and Disorders of Vision, Clinical Trials and Supportive Activities, Clinical Research, Diabetes, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Eye, Adult, Angiogenesis Inhibitors, Clinical Trials, Phase II as Topic, Diabetes Mellitus, Diabetic Retinopathy, Female, Humans, Low-Level Light Therapy, Macular Edema, Male, Middle Aged, Randomized Controlled Trials as Topic, Tomography, Optical Coherence, Visual Acuity, Diabetic macular edema, DRCR Retina Network, photobiomodulation, Ophthalmology and optometry
Abstract

PurposeTo determine if treatment with a photobiomodulation (PBM) device results in greater improvement in central subfield thickness (CST) than placebo in eyes with center-involved diabetic macular edema (CI-DME) and good vision.DesignPhase 2 randomized clinical trial.ParticipantsParticipants had CI-DME and visual acuity (VA) 20/25 or better in the study eye and were recruited from 23 clinical sites in the United States.MethodsOne eye of each participant was randomly assigned 1:1 to a 670-nm light-emitting PBM eye patch or an identical device emitting broad-spectrum white light at low power. Treatment was applied for 90 seconds twice daily for 4 months.Main outcome measuresChange in CST on spectral-domain OCT at 4 months.ResultsFrom April 2019 to February 2020, 135 adults were randomly assigned to either PBM (n = 69) or placebo (n = 66); median age was 62 years, 37% were women, and 82% were White. The median device compliance was 92% with PBM and 95% with placebo. OCT CST increased from baseline to 4 months by a mean (SD) of 13 (53) μm in PBM eyes and 15 (57) μm in placebo eyes, with the mean difference (95% confidence interval [CI]) being -2 (-20 to 16) μm (P = 0.84). CI-DME, based on DRCR Retina Network sex- and machine-based thresholds, was present in 61 (90%) PBM eyes and 57 (86%) placebo eyes at 4 months (adjusted odds ratio [95% CI] = 1.30 (0.44-3.83); P = 0.63). VA decreased by a mean (SD) of -0.2 (5.5) letters and -0.6 (4.6) letters in the PBM and placebo groups, respectively (difference [95% CI] = 0.4 (-1.3 to 2.0) letters; P = 0.64). There were 8 adverse events possibly related to the PBM device and 2 adverse events possibly related to the placebo device. None were serious.ConclusionsPBM as given in this study, although safe and well-tolerated, was not found to be effective for the treatment of CI-DME in eyes with good vision.

Published
2022

16. Narrating the "what" and "why" of our moral actions

Author

Kim, Judy and Crockett, Molly J

Subjects
Psychology, Language Production, Language understanding, Pragmatics, Social cognition
Abstract

To defend or burnish our moral reputation, we often tell moral narratives. Moral narratives describe morally relevant actions and explanations of those actions, detailing how people acted and why they did so. When and why does communication about moral events include descriptions of peoples’ actions and explanations? We hypothesize that informational, reputational, and presentational goals of narrators shape whether their communication contains clear actions and explanations. We asked a group of “narrators” to communicate with other people following a moral decision. Another group of “audience” members judged them based on their chosen statement. We find that the informational and reputational goals of narrators can explain what information they decide to reveal. Narrators choose what to say based on inferring the audience’s likely perceptions but underestimate how much audiences in fact expect answers to “what” and “why”. Audiences, however, do not always perceive the lack of expected information as indicative of deceit.

Published
2022

17. Assessment of Baseline Ultrawidefield Fluorescein Angiographic Quantitative Leakage Parameters with Ultrawidefield Fundus Features and Clinical Parameters in Diabetic Retinopathy in Protocol AA

Author

Harara, Abla M., Palacios, Angela N., Berger, Brian B., Corak, Boris, Luong, Bianca, Jhaveri, Chirag D., Wilson, Daniela Mariel, Jonna, Gowtham, Gunderson, Ivana, Hosein, Kimberly, Reid, Ryan M., Chexal, Saradha, Moore, Tori, Seidu, Tina A., Gatavaski, Valerie, Ren, Yong, Stern, Bradley A., Benvenutti, Celia E., Oude-Reimerink, Dinah S., Shaheen, Jenny, Grybas, John, Vitale-Kuhn, Julianne, Staffne, Jessica L., Ventimiglia, Katie M., Allis, Megan, Monk, Mary K., Thomas, Marc E., Massu, Nicole M., Edwards, Paul Andrew, Troszak, Tracy A., Irons, Amber N., Rego, Brittany, Han, Dennis P., Dorsey, Eleanor, Nelson, Erika, Sheppard, Hannah, Beringer, Joseph R., Kim, Judy E., Keller, Kristy L., Packard, Krissa L., Altmann, Marriner L., Goldberg, Mara, Chen, Nickolas, Winter, Pat A., Bourgeois, Shay, Jacobo, Samantha, Moebius, Stephanie J., Connor, Thomas B., Barwick, Vicki, Williams, Vesper V., Wirostko, William J., Ghuman, A. Thomas, Leslie, Anita H., Sharma, Ashish G., Kiesel, Cheryl, Dyshanowitz, Danielle, Knips, Eileen, Wing, Glenn, Walker, Joseph P., Raskauskas, Paul A., Kiesel, Raymond K., Schlossman, Deborah K., Weimann, Elizabeth S., Sharuk, George S., Kwak, Hanna, Cavallerano, Jerry D., Rhee, Jae W., Sampani, Konstantina, Tran, Katie V., Bestourous, Leila, Miranda, Linette, Krigman, Michael N., Stockman, Margaret E., Arrigg, Paul G., Cavicchi, Robert W., Kirby, Rita K., Glynn, Shireen, Papaconstantinou, Steve L., Shah, Sabera T., Murtha, Timothy J., Carli, William, Finch, Autumn K., Gentile, Angella K., Price, Angela K., Murphy, Brittany A., Rowland, Beverly O., Fleming, Christina J., Mahr, Courtney, Shore, Carol A., Browning, David, McClain, Donna, Breglio, Erica, Lester, Gina M., Herby, Jenna T., Bratcher, Kayla A., Clark, Loraine M., Jackson, Lisa A., Watson, Lynn, McOwen, Michael D., Punjabi, Omar S., Bojaj, Swann J., Ennis, Sarah A., Fredenberg, Sherry L., Jones, Taylor S., Ragin, Teneisha A., Balasubramaniam, Uma M., Ornelas, Blanca, Rodriquez, Brenda, Edwards, Carla, Carns, Danielle R., Tonner, Eileen E., Woo, Kisung, Richine, Len, MacCumber, Mathew W., Merrill, Pauline Townsend, Kociborski, Sarah, Harless, Ashley M., Harris, Charlotte, White, Lorraine, Maturi, Raj K., Asher, Julie, Walsh, Justin, Wheeler, Jeff, Milstead, Katie, Oliver, Kristina, Lovelady, Lisa, Anderson, Nicholas G., Coppola, Patricia, Lince, Raul E., Shuler, R. Keith, Morris, Steve, Oelrich, Sarah M., Gardner, Brandon S., Moore, Bob, Cain, Dennis, Donohue, Deborah, Emmert, David, Adeyemo, Kemi, Levin, Lisa K., Frey, Mary, Rhoton, Nick, Bressler, Susan, Solomon, Sharon D., Ford, Amy L., Hughes, Ashley, Brewer, Alisha N., Booth, JoAnn T., Lunsford, Keven W., Ukleya, Lauren D., Burris, Russ, Kingsley, Ronald M., Almeida, Shannon R., Icks, Sonny, Shah, Vinay A., Bergman, Vanessa A., Castellarin, Alessandro A., Shook, Aimee H., Walker, Aimee, Pieramici, Dante J., Hong, Gina, Avery, Kelly, McKee, Kate M., Giust, Matthew, Munoz, Marco A., Fishbein, Sarah, Camp, Alecia B., Baker, Carl W., Baker, Jil D., Sedberry, Kylie S., Lambert, Lynnette F., Orr, Margaret J., Alcaraz, Sonya L., Kettler, Samantha, Caldwell, Tracey M., Miller, Abigail, Dorr, Christine M., Hampton, G. Robert, Brown, Jamin S., Barker, Jeffrey P., Rosenberg, Kevin I., Kwasniewski, Lynn M., Sienkiewycz, Laurie J., Spuches, Lisa, Manley, Michelle L., Robarge, Nicole E., DeSantis, Stefanie R., DeForge, Teresa M., Brucker, Alexander J., Kim, Benjamin J., Berger, Jim M., DuPont, Joan C., Drossner, Sheri, Freeman, Sara, Studebaker, Ashley, Payne, John F., Wells, John A., Spivey, Robbin, Ogbuewu, Tiffany N., Swinford, Tiffany R., Guillory, Adrienne, Hutson, Amy, Schefler, Amy C., Shah, Ankoor R., Almanza, Belinda A., Dives, Brenda, Richter, Beau A., Stoever, Cary A., Brown, David M., Foerster, Danee, Garcia, David, Rodriguez, Diana, Park, Daniel, Chen, Eric, Kegley, Eric N., Quellar, Elizabeth, Twining, Garret L., Koger-Grifaldo, Heather, Ortega, Ilsa, Carranza, Jolene, Major, James C., Williamson, Kimberly, Burt, Lindsay, Salinas, Luis R., Wolff, Lisa M., Benz, Matthew S., Estes, Maura A., James, Miranda F., Berry, Meredith, Vela, Melina, Landaverde, Nubia, Webb, Nina A., Fish, Richard H., Kim, Rosa Y., Yee, Rebecca, Karani, Sadia Y., Supapo, Stacy M., Dodel, Tamara L., McCoy, Tyneisha, Wong, Tien P., Sneed, Veronica A., Barnhart, Cassandra J., Cantrell, Debra, DuBose, Elizabeth L., Sharpe, Houston P., Ulrich, Jan Niklas, Bhansali, Kanika A., Esquejo, Rona Lyn, Garg, Seema, Grout, Sean, McKinney, Allen, Bobbitt, Brenda J., Wendel, Ceara L., Fagan, Damanda F., Andrews, Jacqueline, Holmes, Krystal Nikki, Seyez, Karen L., Williamson, Kimberly A., Moinfar, Nader, Walters, Paige N., Carlton, Steve, Rehling, Shannon M., Williams, Shana E., Reed, Tiara L., VandeVelde, Amber R., Yeager, Frank T., Fox, Gregory M., Batlle, Ivan R., Bruce, Kiersten, Pippin, Katherine, Ainley, Lexie R., Singh, Ravi S.J., Adamo, Ashley M., Guardado, Adrian, Patel, Apurva K., Puckett, Brian S., Hoerner, Christine, Ma, Colin, Clark, David J., Flato, Inessa M., Cohen, Joshua, Charpentier, Margaret E., Kopfer, Marcia, Peters, Mark A., Smith, Pualani, Tlucek, Paul S., Hobbs, Stephen, Ho, Stephanie L., Metzger, Ashley M., McCalla, Alesia K., Thompson, Amy, Ringrose, Christine, Sandler, Dallas R., Leder, Henry A., Belz, Jennifer L., Starr, JoAnn, Simmons, Jennifer L., Orr, Peggy R., Sotirakos, Peter, Singletary, Pamela V., Cain, Terri, Coffey, Teresa, Carter, Tiffany M., Robinson, Twyla J., Shah, Chirag P., Cammarata, Dominique, Kruger, Jennifer L., Colegrove, Lindsey, Graham, Margie, Gleason, Shane T., Noel, Bryan, Damron, Catherine, Holcomb, Diana M., Slade, Edward A., Van Arsdall, Jeanne, Bicknell, Lisa, Buck, Michelle, Stone, Thomas W., Farooq, Amina, Parsons, Brook, Singh, Harinderjit, Ivey, Ken, Foster, Lindsay Allison, Woodward, Michele, Ortiz, Siobhan O., Bailey, Thomas, Mynampati A, Bharani Krishna, White, Cheryl L., Hamdani, Ghulam Shabbir, Smith, Jazzmin N., Chalam, Kakarla V., Sambhav, Kumar, Babaria, Romesh, Grover, Sandeep, Carroll, Catherine, Chau, Felix Y., Lim, Jennifer I., Talasnik, Lauren A., Janowicz, Mark, Stankovic, Natasa, Berlatsky, Sarah L., Niec, Marcia, Sun, Jie, Johnson, Tametha, Ovando, Yesenia, Nakoski, Brenda, Mein, Calvin E., Wienecke, Christopher Sean, Castillo, Elaine, Baker, Jaynee, San Roman, Jonathan, Adams, Lydia, Kirschbaum, Lita, Chica, Moises A., Cloudt, Sara L., Moore, Tori R., Sabates, Felix N., Gallimore, Gary S., Chen, Yin C., Swann, Adrienne C., Cadwell, Deborah M., Diddie, Kenneth R., Boisvert, Taryn F., Tessau, Carrie D., Bowers, Jack, Nielsen, Jared S., Rostvold, Jay, Spillman, Jamie, Alliman, Kyle J., Boender, Lisa M., Johnson, Marilyn A., Parker, Marianne, Bix, Paula L., Ridgway, Spencer D., Woehl, Tami Jo, Stonewall, Whitney, Brown, Christopher M., Lema, Gareth M.C., Wiechelt, Luann, Yoganathan, Pradeepa, Boglione, Sandra L., Montesclaros, Chris A., Mangham, Cory, Karsaliya, Gopal, Le, Phillip V., Wong, Robert W., Godfrey, Anne Marie, Kuzmanovic, Aleksandra, Kirker, Andrew William, Harrison, Bryan, Forooghian, Farzin, Elvena, Garnet Louise, Hall, Laura J., Turhal, Bilgin, Brown, Ian, Kotei, Isaac A., Chen, Lina, Brent, Michael Henry, Moon, Michelle, Sutakovic, Olivera, Chang, Angela, Godfrey, Anne-Marie, Albiani, David, Maberley, David A.L., Navajas, Eduardo Vitor, Grant, Kelly, Tran, Khoi A., Jovanovic, Mira, Cao, Sijia, Wiens, Theresa, Kozbial, Andrzej, Orlin, Anton, Lenane, Courtney Nichole, Herder, Susan P., Kiss, Szilard, Reeves, Tom, Cruess, Alan F., Dean, Andrea, Hoskin-Mott, Ann, Morrison, Christine, Caldwell, Meggie D., Hynes, Mitzi, Gupta, R. Rishi, Durling, Stacey, MacDonnell, Trina, Beck, Roy W., Baptista, Alyssa, Beaulieu, Wesley T., Calhoun, Claire T., Constantine, Sharon R., Correia, Isabella, Dale, Brian B., Dupre, Simone S., Franklin, Crystal A., Galusic, Sandra, Huggins, Meagan, Hunter, Brenda L., Johnson, Paula A., Josic, Kristin, Kelly, Brittany, Maguire, Maureen G., Meadows, Britney, Stockdale, Cynthia R., Zokruah, Alice, Bhargava, Sangeeta, Barkmeier, Andrew J., Baskin, Darrell, Blodi, Barbra, Chew, Emily, Ferris, Frederick L., Jaffe, Glenn J., Bressler, Neil M., Lujan, Brandon, Tolls, Dorothy, Sheridan, Daniel, Pitoc, Cloyd M., Anne C Aquino, Lizzie, Salva, Claude Michael G., Lewis, Drew, Stainback, Jeffery, Makkena, Vijaya, Winter, Katrina, Mora, Adiel, Harrington, Chris, Vinh, Doc-Lap, Ehlers, Justis P., Yordi, Sari, Martin, Alison, Srivastava, Sunil K., and Sun, Jenifer K.

Published
2024
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19. mTOCS: Mobile Teleophthalmology in Community Settings to improve Eye-health in Diabetic Population

Author

Tumpa, Jannat, Adib, Riddhiman, Das, Dipranjan, Abenoza, Nathalie, Zolot, Andrew, Medic, Velinka, Kim, Judy, Castro, Al, Pacheco, Mirtha Sosa, Romant, Jay, and Ahamed, Sheikh Iqbal

Subjects
Computer Science - Computers and Society
Abstract

Diabetic eye diseases, particularly Diabetic Retinopathy,is the leading cause of vision loss worldwide and can be prevented by early diagnosis through annual eye-screenings. However, cost, healthcare disparities, cultural limitations, etc. are the main barriers against regular screening. Eye-screenings conducted in community events with native-speaking staffs can facilitate regular check-up and development of awareness among underprivileged communities compared to traditional clinical settings. However, there are not sufficient technology support for carrying out the screenings in community settings with collaboration from community partners using native languages. In this paper, we have proposed and discussed the development of our software framework, "Mobile Teleophthalomogy in Community Settings (mTOCS)", that connects the community partners with eye-specialists and the Health Department staffs of respective cities to expedite this screening process. Moreover, we have presented the analysis from our study on the acceptance of community-based screening methods among the community participants as well as on the effectiveness of mTOCS among the community partners. The results have evinced that mTOCS has been capable of providing an improved rate of eye-screenings and better health outcomes., Comment: Submitted to Elsevier Smart Health Journal

Published
2020

20. Antimony thin films demonstrate programmable optical non-linearity

Author

Cheng, Zengguang, Milne, Tara, Salter, Patrick, Kim, Judy S., Humphrey, Samuel, Booth, Martin, and Bhaskaran, Harish

Subjects
Condensed Matter - Materials Science, Physics - Applied Physics
Abstract

The use of metals of nanometer dimensions to enhance and manipulate light-matter interactions for a range of emerging plasmonics-enabled nanophotonic and optoelectronic applications is an interesting, yet not highly explored area of research outside of plasmonics1,2. Even more importantly, the concept of an active metal, i.e. a metal that can undergo an optical non-volatile transition has not been explored. Nanostructure-based applications would have unprecedented impact on both the existing and future of optics with the development of active and nonlinear optical tunabilities in single elemental metals3-5. Compared to alloys, pure metals have the material simplicity and uniformity; however single elemental metals have not been viewed as tunable optical materials, although they have been explored as viable electrically switchable materials. In this paper we demonstrate for the first time that antimony (Sb), a pure metal, is optically distinguishable between two programmable states as nanoscale thin films. We then show that these states are stable at room temperature, and the states correspond to the crystalline and amorphous phases of the metal. Crucially from an application standpoint, we demonstrate both its optoelectronic modulation capabilities as well as speed of switching using single sub-picosecond (ps) pulses. The simplicity of depositing a single metal portends its potential for use in applications ranging from high speed active metamaterials to photonic neuromorphic computing, and opens up the possibility for its use in any optoelectronic application where metallic conductors with an actively tunable state is important.

Published
2020

22. Competing goals in the construction and perception of moral narratives

Author

Kim, Judy and Crockett, Molly

Subjects
cognitive science
Abstract

Narratives can communicate moral character by describing one's past actions and motivations. When telling moral narratives, people might twist the truth to appear better than they are, while concealing this goal. We show that audiences evaluate a narrator’s moral character by inferring weights on three goals: providing accurate information, appearing morally good, and projecting an image of informativeness. Participants judged how narrators explained their choice during a “claim” task. Narrators could claim a raise at the risk of causing a co-worker to lose money. They could then lie or tell the truth and be direct or indirect about their motivations (e.g., “I’m not selfish” vs. “It was better for the co-worker”). Our results suggest that to be perceived as morally good, narrators must find a balance: trying too hard to appear generous is costly. We introduce a model for how narratives are constructed through recursive inference of audience perception.

Published
2021

23. I see where you are going: Perception of persuasion goals in moral narratives influences character impressions

Author

Colombatto, Clara, Kim, Judy, Rodriguez, Danny, and Crockett, Molly

Subjects
cognitive science
Abstract

Impressions of others’ moral character are key to our social lives, but we rarely directly witness immoral acts, and rather rely on the stories we hear. This creates significant opportunities for narrators to distort their stories in an effort to appear more moral. How does the detection of such persuasion goals affect readers' impressions of the authors' character? Participants read autobiographical stories written by other participants about morally questionable actions they did – written once with no goal, and then again with the goal of appearing morally good or bad. Readers were very accurate in detecting the authors’ goals, but these were nonetheless effective in modulating character impressions. Critically, this effect vanished when readers thought the author didn't care about communicating information accurately. This suggests that audiences sometimes fail to discount narrators' goals when evaluating their character, but only when goals don't come at the cost of communicating information accurately.

Published
2021

25. The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase

Author

Luz, John G, Beigneux, Anne P, Asamoto, DeeAnn K, He, Cuiwen, Song, Wenxin, Allan, Christopher M, Morales, Jazmin, Tu, Yiping, Kwok, Adam, Cottle, Thomas, Meiyappan, Muthuraman, Fong, Loren G, Kim, Judy E, Ploug, Michael, Young, Stephen G, and Birrane, Gabriel

Subjects
Biotechnology, Animals, Antibodies, Monoclonal, Binding Sites, Humans, Lipoprotein Lipase, Mice, Tryptophan, antibodies, lipid metabolism, protein structure, triglycerides, X-ray crystallography, Biochemistry and Cell Biology, Medical Biochemistry and Metabolomics, Biochemistry & Molecular Biology
Abstract

For three decades, the LPL-specific monoclonal antibody 5D2 has been used to investigate LPL structure/function and intravascular lipolysis. 5D2 has been used to measure LPL levels, block the triglyceride hydrolase activity of LPL, and prevent the propensity of concentrated LPL preparations to form homodimers. Two early studies on the location of the 5D2 epitope reached conflicting conclusions, but the more convincing report suggested that 5D2 binds to a tryptophan (Trp)-rich loop in the carboxyl terminus of LPL. The same loop had been implicated in lipoprotein binding. Using surface plasmon resonance, we showed that 5D2 binds with high affinity to a synthetic LPL peptide containing the Trp-rich loop of human (but not mouse) LPL. We also showed, by both fluorescence and UV resonance Raman spectroscopy, that the Trp-rich loop binds lipids. Finally, we used X-ray crystallography to solve the structure of the Trp-rich peptide bound to a 5D2 Fab fragment. The Trp-rich peptide contains a short α-helix, with two Trps projecting into the antigen recognition site. A proline substitution in the α-helix, found in mouse LPL, is expected to interfere with several hydrogen bonds, explaining why 5D2 cannot bind to mouse LPL.

Published
2020

26. Low-dose phase retrieval of biological specimens using cryo-electron ptychography.

Author

Zhou, Liqi, Song, Jingdong, Kim, Judy, Pei, Xudong, Huang, Chen, Boyce, Mark, Mendonça, Luiza, Clare, Daniel, Siebert, Alistair, Allen, Christopher, Liberti, Emanuela, Stuart, David, Nellist, Peter, Zhang, Peijun, Kirkland, Angus, Wang, Peng, and Pan, Xiaoqing

Subjects
Cryoelectron Microscopy, Electrons, HIV-1, Image Processing, Computer-Assisted, Microscopy, Electron, Transmission, Microscopy, Phase-Contrast, Models, Theoretical, Virion
Abstract

Cryo-electron microscopy is an essential tool for high-resolution structural studies of biological systems. This method relies on the use of phase contrast imaging at high defocus to improve information transfer at low spatial frequencies at the expense of higher spatial frequencies. Here we demonstrate that electron ptychography can recover the phase of the specimen with continuous information transfer across a wide range of the spatial frequency spectrum, with improved transfer at lower spatial frequencies, and as such is more efficient for phase recovery than conventional phase contrast imaging. We further show that the method can be used to study frozen-hydrated specimens of rotavirus double-layered particles and HIV-1 virus-like particles under low-dose conditions (5.7 e/Å2) and heterogeneous objects in an Adenovirus-infected cell over large fields of view (1.14 × 1.14 μm), thus making it suitable for studies of many biologically important structures.

Published
2020

27. α-Linolenic acid-enriched butter attenuated high fat diet-induced insulin resistance and inflammation by promoting bioconversion of n-3 PUFA and subsequent oxylipin formation

Author

Fan, Rong, Kim, Judy, You, Mikyoung, Giraud, David, Toney, Ashley M, Shin, Seung-Ho, Kim, So-Youn, Borkowski, Kamil, Newman, John W, and Chung, Soonkyu

Subjects
Biomedical and Clinical Sciences, Nutrition and Dietetics, Obesity, Cardiovascular, Nutrition, Heart Disease, Metabolic and endocrine, Cancer, Oral and gastrointestinal, Animals, Diet, High-Fat, Fatty Acids, Fatty Acids, Omega-3, Fatty Acids, Unsaturated, Glucose Tolerance Test, Inflammation, Insulin, Insulin Resistance, Lipidomics, Liver, Male, Mice, Mice, Inbred C57BL, Oxylipins, alpha-Linolenic Acid, ALA, Butter, Macrophage Polarization, N-6/N-3 PUFA Ratio, Biochemistry and Cell Biology, Food Sciences, Nutrition & Dietetics, Food sciences, Nutrition and dietetics
Abstract

α-Linolenic acid (ALA) is an essential fatty acid and the precursor for long-chain n-3 PUFA. However, biosynthesis of n-3 PUFA is limited in a Western diet likely due to an overabundance of n-6 PUFA. We hypothesized that dietary reduction of n-6/n-3 PUFA ratio is sufficient to promote the biosynthesis of long-chain n-3 PUFA, leading to an attenuation of high fat (HF) diet-induced obesity and inflammation. C57BL/6 J mice were fed a HF diet from ALA-enriched butter (n3Bu, n-6/n-3=1) in comparison with isocaloric HF diets from either conventional butter lacking both ALA and LA (Bu, n-6/n-3=6), or margarine containing a similar amount of ALA and abundant LA (Ma, n-6/n-3=6). Targeted lipidomic analyses revealed that n3Bu feeding promoted the bioconversion of long-chain n-3 PUFA and their oxygenated metabolites (oxylipins) derived from ALA and EPA. The n3Bu supplementation attenuated hepatic TG accumulation and adipose tissue inflammation, resulting in improved insulin sensitivity. Decreased inflammation by n3Bu feeding was attributed to the suppression of NF-κB activation and M1 macrophage polarization. Collectively, our work suggests that dietary reduction of the n-6/n-3 PUFA ratio, as well as total n-3 PUFA consumed, is a crucial determinant that facilitates n-3 PUFA biosynthesis and subsequent lipidomic modifications, thereby conferring metabolic benefits against obesity-induced inflammation and insulin resistance.

Published
2020

28. Folding of the β-Barrel Membrane Protein OmpA into Nanodiscs.

Author

Asamoto, DeeAnn, Kang, Guipeun, and Kim, Judy

Subjects
Amino Acid Sequence, Bacterial Outer Membrane Proteins, Models, Molecular, Mutation, Nanostructures, Protein Conformation, beta-Strand, Protein Folding
Abstract

Nanodiscs (NDs) are an excellent alternative to small unilamellar vesicles (SUVs) for studies of membrane protein structure, but it has not yet been shown that membrane proteins are able to spontaneously fold and insert into a solution of freely diffusing NDs. In this article, we present SDS-PAGE differential mobility studies combined with fluorescence, circular dichroism, and ultraviolet resonance Raman spectroscopy to confirm the spontaneous folding of outer membrane protein A (OmpA) into preformed NDs. Folded OmpA in NDs was incubated with Arg-C protease, resulting in the digestion of OmpA to membrane-protected fragments with an apparent molecular mass of ∼26 kDa (major component) and ∼24 kDa (minor component). The OmpA folding yields were greater than 88% in both NDs and SUVs. An OmpA adsorbed intermediate on NDs could be isolated at low temperature and induced to fold via an increase in temperature, analogous to the temperature-jump experiments on SUVs. The circular dichroism spectra of OmpA in NDs and SUVs were similar and indicated β-barrel secondary structure. Further evidence of OmpA folding into NDs was provided by ultraviolet resonance Raman spectroscopy, which revealed the intense 785 cm-1 structural marker for folded OmpA in NDs. The primary difference between folding in NDs and SUVs was the kinetics; the rate of folding was two- to threefold slower in NDs compared to in SUVs, and this decreased rate can tentatively be attributed to the properties of NDs. These data indicate that NDs may be an excellent alternative to SUVs for folding experiments and offer benefits of optical clarity, sample homogeneity, control of ND:protein ratios, and greater stability.

Published
2020

29. Redder reds, redder purples, but not redder blues: color gradability knowledgeamong blind and sighted adults

Author

Bedny, Marina and Kim, Judy

Abstract

A key characteristic of color perception is that it both categorical and continuous. This is reflected in graded color ad-jective use. This red fruit is redder than the other red fruit sounds more natural than this red fruit is redder than the bluefruit (Kennedy & McNally, 2010). We examined the contribution of first-person sensory experience to color gradabilityunderstanding by working with congenitally blind adults. Blind (n=20) and sighted (n=15) adults rated the naturalness ofstatements describing two objects of the same color (two red mugs), dissimilar colors (red mug, blue mug) or similar col-ors (red mug, purple mug). Both groups judged redder as most natural for two red objects, least for objects with differentcolors (red/blue) and intermediate for objects with similar colors (red/purple). Color similarity had a larger effect for thesighted group. Understanding color gradability does not require first-person perception.

Published
2020

30. Why blueberries are blue: intuitions about color labels among congenitally blindand sighted adults

Author

Kim, Judy and Bedny, Marina

Abstract

Why do we describe blueberries as blue as opposed to white (their inside color)? People might label object colors entirelyaccording to what they see most frequently. We hypothesized instead that labeling takes into account typical viewingconditions (outside/daytime) and object causal history (colors relationship to function; Cohen, 2004). We further predictedthat these intuitions develop independently of visual experience. Sighted (n=15) and congenitally blind (n=20) participantschose one of two color labels for novel objects, described as having different colors (or textures) on the inside/outsideor during daylight/nighttime. On some day/night trials, objects had nighttime-intended functions. Sighted and blindindividuals alike chose observer-centric outside and day colors by default, but switched to nighttime colors when objectshad nighttime functions. First-person visual experience is not required for color-labeling to take into account observercharacteristics and object causal history.

Published
2020

32. Prediction Models for Glaucoma in a Multicenter Electronic Health Records Consortium: The Sight Outcomes Research Collaborative

Author

Wang, Sophia Y., primary, Ravindranath, Rohith, additional, Stein, Joshua D., additional, Amin, Sejal, additional, Edwards, Paul A., additional, Srikumaran, Divya, additional, Woreta, Fasika, additional, Schultz, Jeffrey S., additional, Shrivastava, Anurag, additional, Ahmad, Baseer, additional, Kim, Judy, additional, Bryar, Paul, additional, French, Dustin, additional, Vanderbeek, Brian L., additional, Pershing, Suzann, additional, Wang, Sophia Y., additional, Lynch, Anne M., additional, Patnaik, Jenna, additional, Munir, Saleha, additional, Munir, Wuqaas, additional, Stein, Joshua, additional, DeLott, Lindsey, additional, Stagg, Brian C., additional, Wirostko, Barbara, additional, McMillian, Brian, additional, and Sheybani, Arsham, additional

Published
2024
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34. Effective refractive error coverage in adults aged 50 years and older: estimates from population-based surveys in 61 countries

Author

Bron, Alain, Cheng, Ching-Yu, Fernandes, Arthur, Friedman, David, Gazzard, Andrew, Kahloun, Rim, Kempen, John, Khairallah, Moncef, Lansingh, Van C, Leasher, Janet, Leveziel, Nicolas, Limburg, Hans, Nowak, Michal, Pesudovs, Konrad, Peto, Tunde, Rossetti, Luca, Tahhan, Nina, Varma, Rohit, Alemayehu, Wondu, Arditi, Aries, Dana, Reza, Del Monte, Monte, Deva, jenny, Dreer, Laura, Ehrlich, Josh, Ellwein, Leon, Hammond, Billy, Hartnett, Mary E, Ingram, April, Khanna, Rohit, Kim, Judy, Lim, Jennifer, Morse, Alan, Musch, David, Parodi, Maurizio B, Ramulu, Pradeep, Robin, Alan, Serle, Janet, Shen, Tueng, Sitorus, Rita S, Stambolian, Dwight, Topouzis, Fotis, Tsilimbaris, Miltiadis, Virgili, Gianni, West, Sheila, Ababora, Jafer K, AlSawahli, Heba, Andriamanjato, Hery Harimanitra, Barrenechea, Rosario, Batlle, Juan F, Burnett, Anthea M, Finger, Robert P, Gallarreta, Marcelo, Gomez-Bastar, Pedro A, Gurung, Reeta, Jain, Elesh, Kabona, George E, Kalua, Khumbo, Kandeke, Levi, Karimurio, Jefitha, Kikira, Susan A, Kulkarni, Sucheta, Mathenge, Wanjiku, Mishra, Sailesh Kumar, Mohammadi, Seyed Farzad, Mörchen, Manfred, Muhammad, Nasiru, Mutati, Grace C, Nano, Maria Eugenia, Németh, János, Paduca, Ala, Páez, Alexander, Rabiu, M Mansur, Rif'ati, Lutfah, Salowi, Mohamad Aziz, Sapkota, Yuddha D, Sargent, Nicholas, Thoufeeq, Ubeydulla, Villalobos, Astrid V, Xiao, Biaxiang, Yee Melgar, Mariano, Zhang, Xiu Juan, Bourne, Rupert Richard Alexander, Cicinelli, Maria Vittoria, Sedighi, Tabassom, Tapply, Ian H, McCormick, Ian, Jonas, Jost B, Congdon, Nathan G, Ramke, Jacqueline, Naidoo, Kovin S, Fricke, Timothy R, Burton, Matthew J, Müller, Andreas, Bikbov, Mukharram M, Furtado, João M, Kyari, Fatima, He, Mingguang, Wang, Ya Xing, Vijaya, Lingam, Nangia, Vinay, Brian, Garry, Emamian, Mohammad Hassan, Fotouhi, Akbar, Hashemi, Hassan, Khandekar, Rajiv B, Marmamula, Srinivas, Salomão, Solange, George, Ronnie, Kazakbaeva, Gyulli, Braithwaite, Tasanee, Casson, Robert J, Iwase, Aiko, Gupta, Noopur, Abdianwall, Mohammad H, Wong, Tien Y, Wang, Ningli, Taylor, Hugh R, Flaxman, Seth R, Keel, Stuart, and Resnikoff, Serge

Published
2022
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35. Congenitally Blind Individuals Theories and Inferences About Object Color

Author

Kim, Judy, Yazzolino, Lindsay, Aheimer, Brianna, Manrara, Vernica Montan, and Bedny, Marina

Abstract

Locke argued that persons born blind do not possess true knowledge about color. While prior studies find some knowledgeof color among blind individuals, questions remain about the depth of this knowledge. Do blind individuals merely learninferentially shallow verbal associations (e.g., bananayellow)? We hypothesized instead that blind individuals are morelikely to acquire causally-relevant color information. Blind (n=20) and sighted adults (n=20) reported colors of naturalkinds (e.g. banana) and artifacts (e.g. car) and judged the likelihood that two instances of a type have the same color.Relative to the sighted, blind participants were less likely to know specific object colors (e.g. banana-yellow), but madeidentical inferences about color consistency (more consistent colors for natural kinds). Inferences were similar acrossgroups even for novel objects. Further, blind individuals gave detailed and coherent causal explanations of color origins.Inferentially rich knowledge of sensory categories can develop without first-person experience.

Published
2019

36. UV Resonance Raman Spectroscopy as a Tool to Probe Membrane Protein Structure and Dynamics

Author

Asamoto, DeeAnn K and Kim, Judy E

Subjects
Chemical Sciences, Physical Chemistry, Amino Acids, Bacterial Outer Membrane Proteins, Lipids, Membrane Proteins, Membranes, Spectrophotometry, Ultraviolet, Spectrum Analysis, Raman, Tryptophan, Tyrosine, Vibration, UV resonance Raman, Membrane proteins, Vibrational spectroscopy, Small unilamellar vesicles, Other Chemical Sciences, Biochemistry and Cell Biology, Developmental Biology, Biochemistry and cell biology, Medicinal and biomolecular chemistry
Abstract

Ultraviolet resonance Raman (UVRR) spectroscopy is a vibrational technique that reveals structures and dynamics of biological macromolecules without the use of extrinsic labels. By tuning the Raman excitation wavelength to the deep UV region (e.g., 228 nm), Raman signal from tryptophan and tyrosine residues are selectively enhanced, allowing for the study of these functionally relevant amino acids in lipid and aqueous environments. In this chapter, we present methods on the UVRR data acquisition and analysis of the tryptophan vibrational modes of a model β-barrel membrane protein, OmpA, in folded and unfolded conformations.

Published
2019

38. Intuitive Theories and the Cultural Evolution of Morality.

Author

Crockett, M. J., Kim, Judy S., and Shin, Yeon Soon

Subjects
*SOCIAL cognitive theory, *SOCIAL evolution, *MORAL norms, *SOCIAL norms, *SOCIAL learning, *ACTIVE learning
Abstract

We explore the role of intuitive theories in the cultural evolution of moral cognition, integrating recent work across subfields of psychology and suggesting directions for future research. Focusing on intuitive theories in the moral domain concerning how people judge the moral value of actions and make inferences about moral character, we review evidence that the specific forms these theories take vary across individuals and can change via social learning. We propose that cultural selection can operate over the intuitive theories people apply in the moral domain, in which particular variants of intuitive moral theories can be more "successful" to the extent that they are cognitively efficient or provide reputational benefits. Finally, we explore some implications of considering moral cognition as a kind of cultural technology that can be innovated, considering whether intuitive moral theories help or hinder our ability to improve our collective moral norms or practices. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Cover Image

Author

Lim, Rayne R., primary, Mahaling, Binapani, additional, Tan, Alison, additional, Mehta, Milan, additional, Kaur, Charanjit, additional, Hunziker, Walter, additional, Kim, Judy E., additional, Barathi, Veluchamy A., additional, Ghosh, Arkasubhra, additional, and Chaurasia, Shyam S., additional

Published
2024
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45. Ocular Ischemic Syndrome

Author

Kim, Judy E., Hwang, Eileen S., Saxena, Sandeep, Series Editor, Spaide, Richard F., Series Editor, Souied, Eric H., Series Editor, Lai, Timothy Y.Y., Series Editor, Sheyman, Alan, editor, and Fawzi, Amani A., editor

Published
2020
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46. Moral dilemmas and trust in leaders during a global health crisis

Author

Everett, Jim A. C., Colombatto, Clara, Awad, Edmond, Boggio, Paulo, Bos, Björn, Brady, William J., Chawla, Megha, Chituc, Vladimir, Chung, Dongil, Drupp, Moritz A., Goel, Srishti, Grosskopf, Brit, Hjorth, Frederik, Ji, Alissa, Kealoha, Caleb, Kim, Judy S., Lin, Yangfei, Ma, Yina, Maréchal, Michel André, Mancinelli, Federico, Mathys, Christoph, Olsen, Asmus L., Pearce, Graeme, Prosser, Annayah M. B., Reggev, Niv, Sabin, Nicholas, Senn, Julien, Shin, Yeon Soon, Sinnott-Armstrong, Walter, Sjåstad, Hallgeir, Strick, Madelijn, Sul, Sunhae, Tummers, Lars, Turner, Monique, Yu, Hongbo, Zoh, Yoonseo, and Crockett, Molly J.

Published
2021
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49. Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study

Author

Steinmetz, Jaimie D, Bourne, Rupert R A, Briant, Paul Svitil, Flaxman, Seth R, Taylor, Hugh R B, Jonas, Jost B, Abdoli, Amir Aberhe, Abrha, Woldu Aberhe, Abualhasan, Ahmed, Abu-Gharbieh, Eman Girum, Adal, Tadele Girum, Afshin, Ashkan, Ahmadieh, Hamid, Alemayehu, Wondu, Alemzadeh, Sayyed Amirpooya Samir, Alfaar, Ahmed Samir, Alipour, Vahid, Androudi, Sofia, Arabloo, Jalal, Arditi, Aries Berhe, Aregawi, Brhane Berhe, Arrigo, Alessandro, Ashbaugh, Charlie, Ashrafi, Elham Debalkie, Atnafu, Desta Debalkie, Bagli, Eleni Amin, Baig, Atif Amin Winfried, Bärnighausen, Till Winfried, Battaglia Parodi, Maurizio, Beheshti, Mahya Srikanth, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bijani, Ali, Bikbov, Mukharram, Bottone, Michele, Braithwaite, Tasanee M, Bron, Alain M, Burugina Nagaraja, Sharath A, Butt, Zahid A, Caetano dos Santos, Florentino Luciano L, Carneiro, Vera L James, Casson, Robert James, Cheng, Ching-Yu Jasmine, Choi, Jee-Young Jasmine, Chu, Dinh-Toi, Cicinelli, Maria Vittoria M, Coelho, João M G, Congdon, Nathan G A, Couto, Rosa A A, Cromwell, Elizabeth A M, Dahlawi, Saad M, Dai, Xiaochen, Dana, Reza, Dandona, Lalit, Dandona, Rakhi A, Del Monte, Monte A, Derbew Molla, Meseret, Dervenis, Nikolaos Alemayehu, Desta, Abebaw Alemayehu P, Deva, Jenny P, Diaz, Daniel, Djalalinia, Shirin E, Ehrlich, Joshua R, Elayedath, Rajesh Rashad, Elhabashy, Hala Rashad B, Ellwein, Leon B, Emamian, Mohammad Hassan, Eskandarieh, Sharareh, Farzadfar, Farshad G, Fernandes, Arthur G, Fischer, Florian S, Friedman, David S M, Furtado, João M, Gaidhane, Shilpa, Gazzard, Gus, Gebremichael, Berhe, George, Ronnie, Ghashghaee, Ahmad, Gilani, Syed Amir, Golechha, Mahaveer, Hamidi, Samer Randall, Hammond, Billy Randall R, Hartnett, Mary Elizabeth R Kusuma, Hartono, Risky Kusuma, Hashi, Abdiwahab I, Hay, Simon I, Hayat, Khezar, Heidari, Golnaz, Ho, Hung Chak, Holla, Ramesh, Househ, Mowafa J, Huang, John J Emmanuel, Ibitoye, Segun Emmanuel M, Ilic, Irena M D, Ilic, Milena D D, Ingram, April D Naghibi, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Itumalla, Ramaiah, Jayaram, Shubha Prakash, Jha, Ravi Prakash, Kahloun, Rim, Kalhor, Rohollah, Kandel, Himal, Kasa, Ayele Semachew, Kavetskyy, Taras A, Kayode, Gbenga A H, Kempen, John H, Khairallah, Moncef, Khalilov, Rovshan Ahmad, Khan, Ejaz Ahmad C, Khanna, Rohit C, Khatib, Mahalaqua Nazli Ahmed, Khoja, Tawfik Ahmed E, Kim, Judy E, Kim, Yun Jin, Kim, Gyu Ri, Kisa, Sezer, Kisa, Adnan, Kosen, Soewarta, Koyanagi, Ai, Kucuk Bicer, Burcu, Kulkarni, Vaman P, Kurmi, Om P, Landires, Iván Charles, Lansingh, Van Charles L, Leasher, Janet L E, LeGrand, Kate E, Leveziel, Nicolas, Limburg, Hans, Liu, Xuefeng, Madhava Kunjathur, Shilpashree, Maleki, Shokofeh, Manafi, Navid, Mansouri, Kaweh, McAlinden, Colm Gebremichael, Meles, Gebrekiros Gebremichael M, Mersha, Abera M, Michalek, Irmina Maria R, Miller, Ted R, Misra, Sanjeev, Mohammad, Yousef, Mohammadi, Seyed Farzad Abdu, Mohammed, Jemal Abdu H, Mokdad, Ali H, Moni, Mohammad Ali Al, Montasir, Ahmed Al R, Morse, Alan R Fentaw, Mulaw, Getahun Fentaw C, Naderi, Mehdi, Naderifar, Homa S, Naidoo, Kovin S, Naimzada, Mukhammad David, Nangia, Vinay, Narasimha Swamy, Sreenivas Muhammad, Naveed, Dr Muhammad, Negash, Hadush Lan, Nguyen, Huong Lan, Nunez-Samudio, Virginia Akpojene, Ogbo, Felix Akpojene, Ogundimu, Kolawole T, Olagunju, Andrew T E, Onwujekwe, Obinna E, Otstavnov, Nikita O, Owolabi, Mayowa O, Pakshir, Keyvan, Panda-Jonas, Songhomitra, Parekh, Utsav, Park, Eun-Cheol, Pasovic, Maja, Pawar, Shrikant, Pesudovs, Konrad, Peto, Tunde Quang, Pham, Hai Quang, Pinheiro, Marina, Podder, Vivek, Rahimi-Movaghar, Vafa, Rahman, Mohammad Hifz Ur Y, Ramulu, Pradeep Y, Rathi, Priya, Rawaf, Salman Laith, Rawaf, David Laith, Rawal, Lal, Reinig, Nickolas M, Renzaho, Andre M, Rezapour, Aziz L, Robin, Alan L, Rossetti, Luca, Sabour, Siamak, Safi, Sare, Sahebkar, Amirhossein, Sahraian, Mohammad Ali M, Samy, Abdallah M, Sathian, Brijesh, Saya, Ganesh Kumar, Saylan, Mete A, Shaheen, Amira A Ali, Shaikh, Masood Ali T, Shen, Tueng T, Shibuya, Kenji Shibabaw, Shiferaw, Wondimeneh Shibabaw, Shigematsu, Mika, Shin, Jae Il, Silva, Juan Carlos, Silvester, Alexander A, Singh, Jasvinder A, Singhal, Deepika S, Sitorus, Rita S, Skiadaresi, Eirini Yurievich, Skryabin, Valentin Yurievich Aleksandrovna, Skryabina, Anna Aleksandrovna, Soheili, Amin Bekele, Sorrie, Muluken Bekele A R C, Sousa, Raúl A R C T, Sreeramareddy, Chandrashekhar T, Stambolian, Dwight Girma, Tadesse, Eyayou Girma, Tahhan, Nina Ismail, Tareque, Md Ismail, Topouzis, Fotis Xuan, Tran, Bach Xuan, Tsegaye, Gebiyaw K, Tsilimbaris, Miltiadis K, Varma, Rohit, Virgili, Gianni, Vongpradith, Avina Thu, Vu, Giang Thu, Wang, Ya Xing, Wang, Ningli Hailay, Weldemariam, Abrha Hailay K, West, Sheila K Gebeyehu, Wondmeneh, Temesgen Gebeyehu Y, Wong, Tien Y, Yaseri, Mehdi, Yonemoto, Naohiro, Yu, Chuanhua Sergeevich, Zastrozhin, Mikhail Sergeevich, Zhang, Zhi-Jiang R, Zimsen, Stephanie R, Resnikoff, Serge, and Vos, Theo

Published
2021
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50. Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study

Author

Bourne, Rupert, Steinmetz, Jaimie D, Flaxman, Seth, Briant, Paul Svitil, Taylor, Hugh R, Resnikoff, Serge, Casson, Robert James, Abdoli, Amir, Abu-Gharbieh, Eman, Afshin, Ashkan, Ahmadieh, Hamid, Akalu, Yonas, Alamneh, Alehegn Aderaw, Alemayehu, Wondu, Alfaar, Ahmed Samir, Alipour, Vahid, Anbesu, Etsay Woldu, Androudi, Sofia, Arabloo, Jalal, Arditi, Aries, Asaad, Malke, Bagli, Eleni, Baig, Atif Amin, Bärnighausen, Till Winfried, Battaglia Parodi, Maurizio, Bhagavathula, Akshaya Srikanth, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bijani, Ali, Bikbov, Mukharram, Bottone, Michele, Braithwaite, Tasanee, Bron, Alain M, Butt, Zahid A, Cheng, Ching-Yu, Chu, Dinh-Toi, Cicinelli, Maria Vittoria, Coelho, João M, Dagnew, Baye, Dai, Xiaochen, Dana, Reza, Dandona, Lalit, Dandona, Rakhi, Del Monte, Monte A, Deva, Jenny P, Diaz, Daniel, Djalalinia, Shirin, Dreer, Laura E, Ehrlich, Joshua R, Ellwein, Leon B, Emamian, Mohammad Hassan, Fernandes, Arthur G, Fischer, Florian, Friedman, David S, Furtado, João M, Gaidhane, Abhay Motiramji, Gaidhane, Shilpa, Gazzard, Gus, Gebremichael, Berhe, George, Ronnie, Ghashghaee, Ahmad, Golechha, Mahaveer, Hamidi, Samer, Hammond, Billy Randall, Hartnett, Mary Elizabeth R, Hartono, Risky Kusuma, Hay, Simon I, Heidari, Golnaz, Ho, Hung Chak, Hoang, Chi Linh, Househ, Mowafa, Ibitoye, Segun Emmanuel, Ilic, Irena M, Ilic, Milena D, Ingram, April D, Irvani, Seyed Sina Naghibi, Jha, Ravi Prakash, Kahloun, Rim, Kandel, Himal, Kasa, Ayele Semachew, Kempen, John H, Keramati, Maryam, Khairallah, Moncef, Khan, Ejaz Ahmad, Khanna, Rohit C, Khatib, Mahalaqua Nazli, Kim, Judy E, Kim, Yun Jin, Kisa, Sezer, Kisa, Adnan, Koyanagi, Ai, Kurmi, Om P, Lansingh, Van Charles, Leasher, Janet L, Leveziel, Nicolas, Limburg, Hans, Majdan, Marek, Manafi, Navid, Mansouri, Kaweh, McAlinden, Colm, Mohammadi, Seyed Farzad, Mohammadian-Hafshejani, Abdollah, Mohammadpourhodki, Reza, Mokdad, Ali H, Moosavi, Delaram, Morse, Alan R, Naderi, Mehdi, Naidoo, Kovin S, Nangia, Vinay, Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Ogundimu, Kolawole, Olagunju, Andrew T, Ostroff, Samuel M, Panda-Jonas, Songhomitra, Pesudovs, Konrad, Peto, Tunde, Quazi Syed, Zahiruddin, Rahman, Mohammad Hifz Ur, Ramulu, Pradeep Y, Rawaf, Salman, Rawaf, David Laith, Reinig, Nickolas, Robin, Alan L, Rossetti, Luca, Safi, Sare, Sahebkar, Amirhossein, Samy, Abdallah M, Saxena, Deepak, Serle, Janet B, Shaikh, Masood Ali, Shen, Tueng T, Shibuya, Kenji, Shin, Jae Il, Silva, Juan Carlos, Silvester, Alexander, Singh, Jasvinder A, Singhal, Deepika, Sitorus, Rita S, Skiadaresi, Eirini, Skirbekk, Vegard, Soheili, Amin, Sousa, Raúl A R C, Spurlock, Emma Elizabeth, Stambolian, Dwight, Taddele, Biruk Wogayehu, Tadesse, Eyayou Girma, Tahhan, Nina, Tareque, Md Ismail, Topouzis, Fotis, Tran, Bach Xuan, Travillian, Ravensara S, Tsilimbaris, Miltiadis K, Varma, Rohit, Virgili, Gianni, Wang, Ya Xing, Wang, Ningli, West, Sheila K, Wong, Tien Y, Zaidi, Zoubida, Zewdie, Kaleab Alemayehu, Jonas, Jost B, and Vos, Theo

Published
2021
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