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27 results on '"Kim, Jee-woong"'

2. Alteration in the Morphological and Transcriptomic Profiles of Acinetobacter baumannii after Exposure to Colistin.

Author

Yoon, Eun-Jeong, Mo, Jun Won, Kim, Jee-woong, Jeong, Min Chul, and Yoo, Jung Sik

Subjects
WHOLE genome sequencing, ACINETOBACTER baumannii, SCANNING electron microscopy, TRANSCRIPTOMES, BACTERIAL diseases, COLISTIN
Abstract

Acinetobacter baumannii is often highly resistant to multiple antimicrobials, posing a risk of treatment failure, and colistin is a "last resort" for treatment of the bacterial infection. However, colistin resistance is easily developed when the bacteria are exposed to the drug, and a comprehensive analysis of colistin-mediated changes in colistin-susceptible and -resistant A. baumannii is needed. In this study, using an isogenic pair of colistin-susceptible and -resistant A. baumannii isolates, alterations in morphologic and transcriptomic characteristics associated with colistin resistance were revealed. Whole-genome sequencing showed that the resistant isolate harbored a PmrBL208F mutation conferring colistin resistance, and all other single-nucleotide alterations were located in intergenic regions. Using scanning electron microscopy, it was determined that the colistin-resistant mutant had a shorter cell length than the parental isolate, and filamented cells were found when both isolates were exposed to the inhibitory concentration of colistin. When the isolates were treated with inhibitory concentrations of colistin, more than 80% of the genes were upregulated, including genes associated with antioxidative stress response pathways. The results elucidate the morphological difference between the colistin-susceptible and -resistant isolates and different colistin-mediated responses in A. baumannii isolates depending on their susceptibility to this drug. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Functional Implication of β-Carotene Hydroxylases in Soybean Nodulation

Author

Kim, Yun-Kyoung, Kim, Sunghan, Um, Ji-Hyun, Kim, Kyunga, Choi, Sun-Kang, Um, Byung-Hun, Kang, Suk-Woo, Kim, Jee-Woong, Takaichi, Shinichi, Song, Seok-Bo, Lee, Choon-Hwan, Kim, Ho-Seung, Kim, Ki Woo, Nam, Kyoung Hee, Lee, Suk-Ha, Kim, Yul-Ho, Park, Hyang-Mi, Ha, Sun-Hwa, Verma, Desh Pal S., and Cheon, Choong-Ill

Published
2013

15. Eruptive pseudoangiomatosis

Author

YANG, Jeong Hoon, KIM, Jee Woong, PARK, Hyun Su, JANG, Sang Jai, and CHOI, Jung Chul

Published
2006

16. Overview of Immunoelectron Microscopy

Author

Park, Chang-Hyun, primary, Kim, Hong Lim, additional, Chang, Byung-Joon, additional, Lee, Sang Hoon, additional, Chang, Byung Soo, additional, Bae, Chun-Sik, additional, Cho, Ik-Hyun, additional, Kim, Dong Heui, additional, Han, Jung-Mi, additional, Na, Ji Eun, additional, Choi, Byung-Jin, additional, Kim, Sang-Sik, additional, Kim, Hyun-Wook, additional, Kim, Jee-Woong, additional, Rhyu, Im Joo, additional, and Uhm, Chang-Sub, additional

Published
2018
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22. Altered branching patterns of Purkinje cells in mouse model for cortical development disorder

Author

Kim, Jinkyung, primary, Kwon, Namseop, additional, Chang, Soeun, additional, Kim, Kyong-Tai, additional, Lee, Dongmyeong, additional, Kim, Seunghwan, additional, Yun, So Jeong, additional, Hwang, Daehee, additional, Kim, Jee Woong, additional, Hwu, Yeukuang, additional, Margaritondo, Giorgio, additional, Je, Jung Ho, additional, and Rhyu, Im Joo, additional

Published
2011
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