Search

Your search keyword '"Kim, Eun-Kyong"' showing total 197 results
Start Over Author "Kim, Eun-Kyong"
197 results on '"Kim, Eun-Kyong"'

2. p-RNA

Author

Krishnamurthy, Ramanarayanan, Kim, Eun-Kyong, Campbell, Tammy, Gargaud, Muriel, editor, Irvine, William M., editor, Amils, Ricardo, editor, Claeys, Philippe, editor, Cleaves, Henderson James, editor, Gerin, Maryvonne, editor, Rouan, Daniel, editor, Spohn, Tilman, editor, Tirard, Stéphane, editor, and Viso, Michel, editor

Published
2023
Full Text
View/download PDF

3. Furanose

Author

Krishnamurthy, Ramanarayanan, Campbell, Tammy, Kim, Eun-Kyong, Gargaud, Muriel, editor, Irvine, William M., editor, Amils, Ricardo, editor, Claeys, Philippe, editor, Cleaves, Henderson James, editor, Gerin, Maryvonne, editor, Rouan, Daniel, editor, Spohn, Tilman, editor, Tirard, Stéphane, editor, and Viso, Michel, editor

Published
2023
Full Text
View/download PDF

5. Diagnostic accuracy of dental caries detection using ensemble techniques in deep learning with intraoral camera images.

Author

Kang, Sohee, Shon, Byungeun, Park, Eun Young, Jeong, Sungmoon, and Kim, Eun-Kyong

Subjects
IMAGE recognition (Computer vision), RECEIVER operating characteristic curves, DENTAL caries, DEEP learning, CAMERAS
Abstract

Camera image-based deep learning (DL) techniques have achieved promising results in dental caries screening. To apply the intraoral camera image-based DL technique for dental caries detection and assess its diagnostic performance, we employed the ensemble technique in the image classification task. 2,682 intraoral camera images were used as the dataset for image classification according to dental caries presence and caries-lesion localization using DL models such as ResNet-50, Inception-v3, Inception-ResNet-v2, and Faster R-convolutional neural network according to diagnostic study design. 534 participants whose mean age [SD] was 47.67 [±13.94] years were enrolled. The dataset was divided into training (56.0%), validation (14.0%), and test subset (30.0%) annotated by one experienced dentist as a reference standard about dental caries detection and lesion location. The confusion matrix, area under the receiver operating characteristic curve (AUROC), and average precision (AP) were evaluated for performance analysis. In the end-to-end dental caries image classification, the ensemble DL models had consistently improved performance, in which as the best results, the ensemble model of Inception-ResNet-v2 achieved 0.94 of AUROC and 0.97 of AP. On the other hand, the explainable model achieved 0.91 of AUROC and 0.96 of AP after the ensemble application. For dental caries classification using intraoral camera images, the application of ensemble techniques exhibited consistently improved performance regardless of the DL models. Furthermore, the trial to create an explainable DL model based on carious lesion detection yielded favorable results. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

6. Furanose

Author

Krishnamurthy, Ramanarayanan, primary, Campbell, Tammy, additional, and Kim, Eun-Kyong, additional

Published
2022
Full Text
View/download PDF

12. p-RNA

Author

Krishnamurthy, Ramanarayanan, Kim, Eun-Kyong, Campbell, Tammy, Gargaud, Muriel, editor, Irvine, William M., editor, Amils, Ricardo, editor, Cleaves, Henderson James (Jim), II, editor, Pinti, Daniele L., editor, Quintanilla, José Cernicharo, editor, Rouan, Daniel, editor, Spohn, Tilman, editor, Tirard, Stéphane, editor, and Viso, Michel, editor

Published
2015
Full Text
View/download PDF

15. Silibinin induces oral cancer cell apoptosis and reactive oxygen species generation by activating the JNK/c-Jun pathway

Author

Zhang, Haibo, primary, Kim, Hyeonjin, additional, Kim, Si-Yong, additional, Hai, Huang, additional, Kim, Eungyung, additional, Ma, Lei, additional, Kim, Dongwook, additional, Kim, Chae Yeon, additional, Park, Kanghyun, additional, Park, Sijun, additional, Ko, Jiwon, additional, Kim, Eun-Kyong, additional, Kim, Kirim, additional, Ryoo, Zae Young, additional, Yi, Junkoo, additional, and Kim, Myoung Ok, additional

Published
2023
Full Text
View/download PDF

16. Effects of professional toothbrushing among patients with gingivitis.

Author

Noh, Mi‐kyoung, Kim, Eun‐Kyong, Sakong, Joon, and Park, Eun Young

Subjects
HEMORRHAGE prevention, GINGIVITIS, DENTAL plaque, TOOTH care & hygiene, ORAL health, PERIODONTAL pockets, HEALTH behavior, GINGIVAL hyperplasia, DESCRIPTIVE statistics, DATA analysis software
Abstract

Objectives: This study aimed to evaluate the biological and clinical effect of professional toothbrushing on the periodontal health of patients with gingivitis. Methods: We enrolled 21 university students with gingivitis in Jinju City in this study between April 24 and October 28, 2014. A dental hygienist performed a professional toothbrushing routine on the participants twice, once at baseline and after 3 months. Oral examinations were performed at baseline, 3, and 6 months to assess the periodontal health. The patient hygiene performance index, gingival bleeding rate, periodontal pocket depth, amount of gingival sulcus fluid, and number of bacterial colonies in the gingival sulcus (CFU/mL) were evaluated during the oral examination. Results: The patient hygiene performance index, gingival bleeding rate, pocket depth, amount of gingival sulcus fluid, and CFU/mL within the gingival sulcus significantly decreased after professional toothbrushing (p < 0.05), indicating an improvement in the periodontal health. The patient hygiene performance index, gingival bleeding rate, pocket depth, amount of gingival sulcus fluid, and CFU/mL within the gingival sulcus decreased more among those whose pocket depth was 4–5 mm than among those whose PD was ≤3 mm (p < 0.05). Conclusions: Professional toothbrushing improved the periodontal health in patients with gingivitis in respect of both biological and clinical results. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

22. Furanose

Author

Krishnamurthy, Ramanarayanan, Campbell, Tammy, Kim, Eun-Kyong, Gargaud, Muriel, editor, Irvine, William M., editor, Amils, Ricardo, editor, Cleaves, Henderson James (Jim), II, editor, Pinti, Daniele L., editor, Quintanilla, José Cernicharo, editor, Rouan, Daniel, editor, Spohn, Tilman, editor, Tirard, Stéphane, editor, and Viso, Michel, editor

Published
2015
Full Text
View/download PDF

25. Costunolide Induces Apoptosis via the Reactive Oxygen Species and Protein Kinase B Pathway in Oral Cancer Cells

Author

Huang, Hai, primary, Yi, Jun-Koo, additional, Lim, Su-Geun, additional, Park, Sijun, additional, Zhang, Haibo, additional, Kim, Eungyung, additional, Jang, Soyoung, additional, Lee, Mee-Hyun, additional, Liu, Kangdong, additional, Kim, Ki-Rim, additional, Kim, Eun-Kyong, additional, Lee, Youngkyun, additional, Kim, Sung-Hyun, additional, Ryoo, Zae-Young, additional, and Kim, Myoung Ok, additional

Published
2021
Full Text
View/download PDF

27. Furanose

Author

Krishnamurthy, Ramanarayanan, primary, Campbell, Tammy, additional, and Kim, Eun-Kyong, additional

Published
2014
Full Text
View/download PDF

28. p-RNA

Author

Krishnamurthy, Ramanarayanan, primary, Kim, Eun-Kyong, additional, and Campbell, Tammy, additional

Published
2014
Full Text
View/download PDF

32. [6]-Gingerol Suppresses Oral Cancer Cell Growth by Inducing the Activation of AMPK and Suppressing the AKT/mTOR Signaling Pathway

Author

ZHANG, HAIBO, primary, KIM, EUNGYUNG, additional, YI, JUNKOO, additional, HAI, HUANG, additional, KIM, HYEONJIN, additional, PARK, SIJUN, additional, LIM, SU-GEUN, additional, KIM, SI-YONG, additional, JANG, SOYOUNG, additional, KIM, KIRIM, additional, KIM, EUN-KYONG, additional, LEE, YOUNGKYUN, additional, RYOO, ZAEYOUNG, additional, and KIM, MYOUNGOK, additional

Published
2021
Full Text
View/download PDF

34. Thermodynamics and Enzymatic Polymerization of Artificial Metallo-Nucleic Acids AND Investigation of Duplex Formation between GAN and RNA

Author

Kim, Eun Kyong

Subjects
Chemistry, Biochemistry, artificial base-pair, DNA, inosine GNA, Metallo-Nucleic Acid, Metal-mediated base-pair, nonenzymatic oligomerization
Abstract

The exquisite structures and properties of nucleic acids enable them to function in information storage and transfer. Efforts to extend encoding and copy-ing of genetic information to unnatural nucleobases have been made over the years for potential usage in molecular engineering, in addition to expansion of the genetic alphabet. We have explored alternative base pairing through metal com-plexation in the DNA double helix. Synthetic nucleobase deoxyribosides of purine-6-carboxylate (PurC) and purine-2,6-dicarboxylate (PurDC) deoxyribosides were found to pair with their complementary nucleobases, PurC, 6-(2'-pyridyl)-purine (PurP) and 3-pyridyl (3-Py) deoxyribosides, through preferential binding to Cu2+. All of the metallo base-pairs exhibited high thermal stability in DNA du-plexes, and mismatched base-pairs between unnatural and natural nucleobases were highly destabilizing.The DNA stabilizing forces of the metal-mediated base-pairs were utilized to guide polymerization of unnatural nucleotides in the presence of DNA poly-merases. Incorporation of PurC or PurDC mononucleotide against its complemen-tary base in the template was Cu2+ concentration dependent, suggesting that nu-cleotide insertion occurred via metallo base-pair formation and that polymerases can recognize this new metal-mediated base pairing. Although no enzymatic se-lectivity for incorporation of unnatural nucleotides over natural nucleotides was observed, sequential incorporation of PurDC and natural nucleotides allowed for the incorporation and subsequent extension of metallo base-pairs by DNA poly-merases. These results are significant in that metal-mediated unnatural base-pair involving replication is unprecedented.Artificial nucleic acids based on simplified backbones are of great interest as a potential evolutionary progenitor of RNA. While glycol nucleic acid (GNA), which has an acyclic three-carbon backbone and follows the Watson-Crick base pairing rules with higher thermal stability than DNA or RNA has been considered as a candidate progenitor of RNA, the evolutionary relationship between GNA and RNA is unclear due to limited ability of GNA to form heteroduplexes with RNA. We investigated nonenzymatic oligomerization of RNA on GNA templates. However, GNA templates failed to direct oligomerization of activated ribonucleo-tide monomers. Also, cross-pairing experiments with inosine GNA, a guanosine analog, and cytidine in RNA did not show an improvement of the cross-pairing properties between GNA and RNA.

Published
2011

36. Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

Author

Guerrero, Miguel, primary, Urbano, Mariangela, additional, Kim, Eun-Kyong, additional, Gamo, Ana M., additional, Riley, Sean, additional, Abgaryan, Lusine, additional, Leaf, Nora, additional, Van Orden, Lori Jean, additional, Brown, Steven J., additional, Xie, Jennifer Y., additional, Porreca, Frank, additional, Cameron, Michael D., additional, Rosen, Hugh, additional, and Roberts, Edward, additional

Published
2019
Full Text
View/download PDF

40. Subjective chewing ability and health-related quality of life among the elderly.

Author

Cho, Min‐Jeong, Kim, Eun‐Kyong, Cho, Min-Jeong, and Kim, Eun-Kyong

Subjects
QUALITY of life, HEALTH & Nutrition Examination Survey, OLDER people
Abstract

Objective: Chewing ability may reflect the overall oral health, which affects the general health of the elderly. Therefore, we assessed the association between subjective chewing ability and health-related quality of life (HRQOL) among the elderly.Methods: We analysed the data of 3034 elderly people aged ≥65 years from the Korean National Health and Nutrition Examination Survey that was conducted by the Korean government from 2013 to 2015 (KNHANES-VI). Subjective chewing ability was evaluated using a questionnaire, and HRQOL was assessed using EuroQol 5-dimension (EQ-5D) instrument by trained examiners. Covariates, such as socio-demographic, oral health-related and general health-related variables, were investigated.Results: Logistic regression analysis showed that chewing ability was significantly associated with HRQOL in both crude and adjusted model for covariates such as age, gender, economic activity, residence, education, smoking, alcohol, hypertension, diabetes, remaining teeth, denture, CPI, tooth brushing and oral hygiene (crude OR, 2.67; 95% CI, 2.23-3.20) (adjusted OR, 2.36; 95% CI, 1.95-2.86). Chewing ability was also significantly associated with most dimensions of EQ-5D, such as motor ability, self-care, daily activities, pain and discomfort, and anxiety and depression (P < 0.05).Conclusion: Chewing ability was significantly associated with HRQOL, suggesting that elderly people with low chewing ability are more likely to have poor health-related quality of life. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results