276 results on '"Kilic, Omer"'
Search Results
2. Pneumococcal carriage and serotype distribution in children with nephrotic syndrome
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Erem, Tugba, Tufan, Asli Kavaz, Kilic, Omer, Yilmaz, Aysun Caltik, Kara, Yalcın, Kizil, Mahmut Can, Dinleyici, Meltem, Cetin, Nuran, Kaya, Mucahit, and Dinleyici, Ener Cagri
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- 2024
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3. Synthesis, Characterization, and Biological Activities of Ag-Au Nanoparticles Using Heliotropium eichwaldi L. Extract as a Reducing and Stabilizing Agent
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Sher, Naila, Ahmed, Mushtaq, Mushtaq, Nadia, and Kilic, Omer
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- 2024
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4. Integrating morpho pollinic traits for systematic classification of rubiaceous species and conservation implications
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Ullah, Tariq, Zafar, Muhammad, Ahmad, Mushtaq, Alkahtani, Jawaher, Elshikh, Mohamed Soliman, Makhkamov, Trobjon, Yuldashev, Akramjon, Kilic, Omer, Sultana, Shazia, Majeed, Salman, Mamarakhimov, Oybek, Botirova, Laziza, and Nizomova, Maxsuda
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- 2024
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5. Phyto-ecological studies and distribution patterns of subfamily Polygonoideae in relation to edaphic factors across diverse ecological zones
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Gillani, Syed Waseem, Ahmad, Mushtaq, Ali, M. Ajmal, Zafar, Muhammad, Alkahtani, Jawaher, Makhkamov, Trobjon, Yuldashev, Akramjon, Mamarakhimov, Oybek, Khaydarov, Khislat, Botirova, Laziza, Kilic, Omer, Shaheen, Hamayun, Idrees, Muhammad, Sultana, Shazia, Manzoor, Muhammad, and Majeed, Salman
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- 2024
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6. Foliar epidermal and trichome micromorphological diversity among poisonous plants and their taxonomic significance
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Abid Aqsa, Ahmad Mushtaq, Zafar Muhammad, Zafar Sadia, Ramadan Mohamed Fawzy, Althobaiti Ashwaq T., Sultana Shazia, Kilic Omer, Makhkamov Trobjon, Yuldashev Akramjon, Mamarakhimov Oybek, Khaydarov Khislat, Mammadova Afat O., Komilov Komiljon, and Majeed Salman
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biodiversity ,foliar epidermis ,microanatomy ,stellate trichomes ,taxonomy ,Plant culture ,SB1-1110 - Abstract
Scanning microscopic imaging has become a valuable research tool in micromorphology with improved techniques playing an important role in analysing the ultrastructure of leaf specimens. The foliar epidermal anatomy of 25 selected poisonous plants with special emphasis on stomata and trichomes was reported using microscopic techniques, for instance, light micrographs (LMs) and scanning micrographs (SEMs). This study aimed to investigate micromorphologies of studied species that are helpful for the identification of poisonous plants. Plants were collected, pressed, dried, identified and then analysed for microscopic study. For making microscopic slides, 1 or 2 leaves were taken in a test tube and dipped in 30% nitric acid and 70% lactic acid for few minutes, and then placed on petri plates for separating the epidermis. Numerous quantitative and qualitative foliar anatomical features of adaxial and abaxial surfaces, including epidermal cell shapes, stomata size, subsidiary cell size, the pattern of the anticlinal wall, the morphology of the stomatal complex and trichome diversity, were examined. A small number of the considered species had anomocytic and anisocytic stomata; a few species had paracytic stomata, for instance, Ricinus communis, Euphorbia royleana, Buxus pilosula and Sorghum halepense; and only Ipomoea carnea had cyclocytic stomata in the studied taxa. The epidermal cells of the analysed species were irregular, while some exhibited polygonal, wavy, tetragonal and elongated cell morphologies. Overall, this study emphasises the significance of foliar micromorphology analysis as a valuable resource for identifying potentially poisonous plants and demonstrates its contribution to maintaining public welfare, thereby benefitting public health and safety.
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- 2023
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7. Comparison of Bordetella pertussis Antibody Levels in Pregnant Women and Umbilical Cord Blood: A Multicenter Study
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Iseri Nepesov, Merve, Kilic, Halime, Yildirim, Sukran, Gulec, Sevgi, Kara, Yalcin, Kizil, Mahmut Can, Karbuz, Adem, Terek, Demet, Sutcu, Murat, Tufan, Ergun, Dinleyici, Meltem, Kurugol, Zafer, Kilic, Omer, and Dinleyici, Ener Cagri
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- 2024
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8. CIC reduces xCT/SLC7A11 expression and glutamate release in glioma
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Park, Jong-Whi, Kilic, Omer, Deo, Minh, Jimenez-Cowell, Kevin, Demirdizen, Engin, Kim, Hyunggee, and Turcan, Şevin
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- 2023
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9. Appraisal of Medicinal Plants Diversity Inhabited in Deserts Areas
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Majeed, Salman, Zafar, Muhammad, Ahmad, Mushtaq, Sultana, Shazia, Ozdemir, Fethi Ahmet, Kilic, Omer, Yaseen, Ghulam, Nabila, Arunachalam, Karuppusamy, editor, Yang, Xuefei, editor, and Puthanpura Sasidharan, Sreeja, editor
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- 2023
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10. Bedeutung der technischen Gebäudeausrüstung von Industrieimmobilien und ihre Auswirkungen auf den Immobilienwert
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Can, Korhan, Kilic, Omer Bahadir, Kesef, Caner, Everling, Oliver, editor, and Salostowitz, Peter, editor
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- 2023
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11. Severe Course of Lung Abscess due to Multidrug Resistant Proteus mirabilis and Escherichia coli
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Kiral, Eylem, Oztunali, Cigdem, Bozan, Gurkan, Kilic, Omer, and Dinleyici, Ener Cagri
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- 2023
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12. Prospects of Bioenergy Development in Future
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Ameen, Maria, primary, Zafar, Muhammad, additional, Ahmad, Mushtaq, additional, Sultana, Shazia, additional, Makhkamov, Trobjon, additional, Yuldashev, Akramjon, additional, Mamarakhimov, Oybek, additional, Nasirov, Muhtor, additional, Kilic, Omer, additional, Ozdemir, Fethi A., additional, and Gafforov, Yusufjon, additional
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- 2023
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13. Bedeutung der technischen Gebäudeausrüstung von Industrieimmobilien und ihre Auswirkungen auf den Immobilienwert
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Can, Korhan, primary, Kilic, Omer Bahadir, additional, and Kesef, Caner, additional
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- 2023
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14. Petiole micromorphology in Brassicaceous taxa and its potential for accurate taxonomic identification
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Noor, Wajia, Zafar, Muhammad, Ahmad, Mushtaq, Althobaiti, Ashwaq T., Ramadan, Mohamed Fawzy, Makhkamov, Trobjon, Gafforov, Yusufjon, Yuldashev, Akramjon, Mamarakhimov, Oybek, Kilic, Omer, Eid, Heba F., Şahin, Talip, Sultana, Shazia, Sadia, Bibi, Usma, Anwer, and Khan, Amjad
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- 2023
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15. Intestinal microbiota composition of children with infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and multisystem inflammatory syndrome (MIS-C)
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Suskun, Cansu, Kilic, Omer, Yilmaz Ciftdogan, Dilek, Guven, Sirin, Karbuz, Adem, Ozkaya Parlakay, Aslinur, Kara, Yalcın, Kacmaz, Ebru, Sahin, Aslihan, Boga, Aysun, Kizmaz Isancli, Didem, Gulhan, Belgin, Kanik-Yuksek, Saliha, Kiral, Eylem, Bozan, Gurkan, Arslanoglu, Mehmet Ozgür, Kizil, Mahmut Can, Dinleyici, Meltem, Us, Tercan, Varis, Ahmet, Kaya, Mucahit, Vandenplas, Yvan, and Dinleyici, Ener Cagri
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- 2022
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16. Consecutive Seven Serious Cases with Invasive Group A Streptococcal Infections at December 2022–January 2023
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Kizil, Mahmut Can, Kara, Yalcin, Bozan, Gurkan, Arda, Surhan, Durmaz, Gul, Kilic, Omer, and Dinleyici, Ener Cagri
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- 2023
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17. Indigenous utilization of medicinal plants in Kalasha tribes, District Chitral, Hindukush Range, Pakistan
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Hadi, Fazal, primary, Gul, Alia, additional, Saqibullah, Saqibullah, additional, Noreen, Shumaila, additional, Shah, Ghulam Mujtaba, additional, Kilic, Omer, additional, and Bussmann, Rainer W, additional
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- 2024
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18. COVID-19 associated multisystemic inflammatory syndrome in 614 children with and without overlap with Kawasaki disease-Turk MIS-C study group
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Yilmaz Ciftdogan, Dilek, Ekemen Keles, Yildiz, Cetin, Benhur Sirvan, Dalgic Karabulut, Nazan, Emiroglu, Melike, Bagci, Zafer, Buyukcam, Ayse, Erdeniz, Emine Hafize, Arga, Gul, Yesil, Edanur, Cakici, Ozlem, Karbuz, Adem, Sahbudak Bal, Zumrut, Kara, Soner Sertan, Ozer, Arife, Metin Akcan, Ozge, Elmas Bozdemir, Sefika, Anil, Ayse Berna, Uygun, Hatice, Kilic, Omer, Hancerli Torun, Selda, Umit, Zuhal, Sutcu, Murat, Ozgokce Ozmen, Berfin, Karaoglu Asrak, Hatice, Alkan, Gulsum, Kara Aksay, Ahu, Ugur, Cuneyt, Birbilen, Ahmet Ziya, Bursal Duramaz, Burcu, Akyuz Ozkan, Esra, Burakay, Ozgur, Yildirim Arslan, Sema, Karadag Oncel, Eda, Celik, Serkan Fazli, Kilic, Ahmet Osman, Ozen, Seval, Sarikaya, Remzi, Demirkol, Demet, Arslan, Gazi, Turel, Ozden, Sert, Ahmet, Sari, Ergul, Orbak, Zerrin, Sahin, Irfan Oguz, Varan, Celal, Akturk, Hacer, Tuter Oz, Sadiye Kubra, Durak, Fatih, Oflaz, Mehmet Burhan, Kara, Manolya, Karpuz, Derya, Talip Petmezci, Mey, Hatipoglu, Nevin, Oncel, Selim, Turgut, Mehmet, Elmali, Ferhan, Somer, Ayper, Kuyucu, Necdet, Dinleyici, Ener Cagri, Kurugöl, Zafer, Ciftci, Ergin, and Kara, Ates
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- 2022
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19. Ethnobotany, Medicinal Utilization and Systematics of Opuntia Species from Deserts of Pakistan
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Majeed, Salman, Zafar, Muhammad, Ahmad, Mushtaq, Ozdemir, Fethi Ahmet, Kilic, Omer, Hamza, Mohammed, Sultana, Shazia, Yaseen, Ghulam, Lubna, Raza, Jamil, Ramadan, Mohamed Fawzy, editor, Ayoub, Tamer E. Moussa, editor, and Rohn, Sascha, editor
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- 2021
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20. Micro and Macroscopic Characterization of Traded Nigella sativa Seeds Using Applied Systematics Techniques
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Rashid, Sofia, Zafar, Muhammad, Ahmad, Mushtaq, Sultana, Shazia, Ahmed, Sidra Nisar, Kilic, Omer, Jafari, Seid Mahdi, Series Editor, and Fawzy Ramadan, Mohamed, editor
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- 2021
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21. Bioactive plant waste components targeting oral bacterial pathogens as a promising strategy for biofilm eradication.
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Mashal, Saima, Siddiqua, Aisha, Ullah, Niamat, Baloch, Rabia, Khan, Momin, Hasnain, Syed Zia Ul, Aziz, Muhammad Imran, Huseynov, Elchin, Selakovic, Dragica, Rosic, Gvozden, Makhkamov, Trobjon, Yuldashev, Akramjon, Islamov, Sokhib, Abdullayeva, Nilufar, Khujanazarov, Uktam, Amin, Adnan, Roy, Dijendra Nath, Kiren, Ifrah, Kilic, Omer, and Thathola, Pooja
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PHENOLS ,GALLIC acid ,CINNAMIC acid ,REGULATOR genes ,BIOFILMS ,FOSFOMYCIN ,CIPROFLOXACIN ,DENTAL clinics ,WASTE-to-energy power plants - Abstract
The significance of this study lies in its exploration of bioactive plant extracts as a promising avenue for combating oral bacterial pathogens, offering a novel strategy for biofilm eradication that could potentially revolutionize oral health treatments. Oral bacterial infections are common in diabetic patients; however, due to the development of resistance, treatment options are limited. Considering the excellent antimicrobial properties of phenolic compounds, we investigated them against isolated oral pathogens using in silico and in vitro models. We performed antibiogram studies and minimum inhibitory concentration (MIC), antibiofilm, and antiquorum sensing activities covering phenolic compounds. Bacterial strains were isolated from female diabetic patients and identified by using 16S rRNA sequencing as Pseudomonas aeruginosa, Bacillus chungangensis, Bacillus paramycoides, and Paenibacillus dendritiformis. Antibiogram studies confirmed that all strains were resistant to most tested antibiotics except imipenem and ciprofloxacin. Molecular docking analysis revealed the significant interaction of rutin, quercetin, gallic acid, and catechin with transcription regulator genes 1RO5, 4B2O, and 5OE3. All tested molecules followed drug-likeness rules except rutin. The MIC values of the tested compounds varied from 0.0625 to 0.5 mg/mL against clinical isolates. Significant antibiofilm activity was recorded in the case of catechin (73.5% ± 1.6% inhibition against B. paramycoides), cinnamic acid (80.9% ± 1.1% inhibition against P. aeruginosa), and vanillic acid and quercetin (65.5% ± 1.7% and 87.4% ± 1.4% inhibition, respectively, against B. chungangensis) at 0.25-0.125 mg/mL. None of the phenolic compounds presented antiquorum sensing activity. It was, therefore, concluded that polyphenolic compounds may have the potential to be used against oral bacterial biofilms, and further detailed mechanistic investigations should be performed. [ABSTRACT FROM AUTHOR]
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- 2024
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22. Pathogens in Pediatric Septic Arthritis: A Multi-Center Study in Turkiye (PEDSART Study)
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Iseri Nepesov, Merve, primary, Kilic, Omer, additional, Sali, Enes, additional, Yesil, Edanur, additional, Akar, Asuman, additional, Kaman, Ayse, additional, Metin Akcan, Ozge, additional, Kilic Cil, Merve, additional, Ozlu, Canan, additional, Lacinel Gurlevik, Sibel, additional, Ulusoy, Emel, additional, Cetin, Benhur Sirvan, additional, Akici, Narin, additional, Cakir, Deniz, additional, Uslu Aygun, Fatma Deniz, additional, Hancerli, Cafer Ozgur, additional, Tekin Yilmaz, Ayse, additional, Alkan, Gulsum, additional, Uygun, Hatice, additional, Bucak, Ibrahim Hakan, additional, Bursal, Burcu, additional, Celik, Taylan, additional, Sutcu, Murat, additional, Oz, Fatma Nur, additional, Gayretli Aydin, Zeynep Gokce, additional, Karbuz, Adem, additional, Akturk, Hacer, additional, Kepenekli, Eda, additional, Emiroglu, Melike, additional, Oncel, Selim, additional, Nuhoglu, Cagatay, additional, Korucu, Ismail Hakki, additional, Incesu, Mustafa, additional, Kaya, Ahmet, additional, Bombaci, Hasan, additional, Dinleyici, Meltem, additional, Carman, Kursat Bora, additional, Duman, Murat, additional, Turel, Ozden, additional, Yilmaz, Dilek, additional, Alabaz, Derya, additional, Belet, Nursen, additional, Tanir, Gonul, additional, Turgut, Mehmet, additional, Celebi, Solmaz, additional, Kuyucu, Necdet, additional, Arisoy, Emin Sami, additional, Durmaz, Gul, additional, Kaya, Mucahit, additional, Kara, Ates, additional, and Dinleyici, Ener Cagri, additional
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- 2024
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23. Correction to: Intestinal microbiota composition of children with infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and multisystem inflammatory syndrome (MIS-C)
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Suskun, Cansu, Kilic, Omer, Yilmaz Ciftdogan, Dilek, Guven, Sirin, Karbuz, Adem, Parlakay, Aslinur Ozkaya, Kara, Yalcın, Kacmaz, Ebru, Sahin, Aslihan, Boga, Aysun, Kizmaz Isancli, Didem, Gulhan, Belgin, Kanik-Yuksek, Saliha, Kiral, Eylem, Bozan, Gurkan, Arslanoglu, Mehmet Ozgür, Can Kizil, Mahmut, Dinleyici, Meltem, Us, Tercan, Varis, Ahmet, Kaya, Mucahit, Vandenplas, Yvan, and Cagri Dinleyici, Ener
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- 2022
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24. Contributors
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Abdullah, Mohd Azmuddin, primary, Afzal, Muhammad, additional, Ahmad, Mushtaq, additional, Ahmad, Sadaf, additional, Ahmed, Sidra Nisar, additional, Ahmed, Syed Riaz, additional, Akhtar, Majid Niaz, additional, Akram, Abida, additional, Alañón, María Elena, additional, Ali, Zulfiqar, additional, Ashraf, Asma, additional, Azeem, Farrukh, additional, Batool, Riffat, additional, Cecilia, Juan A., additional, Chaudhary, Muhammad Fahad, additional, de la Luz Cádiz-Gurrea, María, additional, del Carmen Villegas-Aguilar, María, additional, Dolzhenko, Anton V., additional, Fernández-Ochoa, Álvaro, additional, García-Sancho, Cristina, additional, Gharabeiki, Ariga, additional, Haider, Ali, additional, Hayat, Samreen, additional, Hussain, Sabir, additional, Hussein, Hanaa Ali, additional, Iftikhar, Kainat, additional, Ijaz, Usman, additional, Imran, Muhammad, additional, Irshad, Aamna, additional, Jiménez-Gómez, Carmen P., additional, Kanwal, Hira, additional, Kargari, Ali, additional, Kilic, Omer, additional, Leyva-Jiménez, Francisco Javier, additional, Maireles-Torres, Pedro, additional, Mandal, Peetam, additional, Maqbool, Fareeha, additional, Mehmood, Iqra, additional, Muzammil, Aqsa, additional, Muzammil, Saima, additional, Nadeem, Habib Ullah, additional, Nazir, Muhammad Shahid, additional, Nnamani, Daniel Okwudili, additional, Onyekere, Peculiar Feenna, additional, Peculiar-Onyekere, Chioma Obianuju, additional, Pimentel-Moral, Sandra, additional, Rasheed, Asima, additional, Rasool, Danish, additional, Rasul, Ijaz, additional, Riaz, Fatima, additional, Saha, Mitali, additional, Samra, Hafeez, additional, Segura-Carretero, Antonio, additional, Shafique, Aimen, additional, Shahzad, Tanvir, additional, Siddique, Muhammad Hussnain, additional, Sultana, Shazia, additional, Uzor, Philip F., additional, Waris, Karistofar, additional, Waseem, Muhammad, additional, Yaseen, Ghulam, additional, Zafar, Muhammad, additional, and Zubair, Muhammad, additional
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- 2021
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25. Current status of solvents used in the pharmaceutical industry
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Yaseen, Ghulam, primary, Ahmad, Mushtaq, additional, Zafar, Muhammad, additional, Akram, Abida, additional, Sultana, Shazia, additional, Kilic, Omer, additional, and Sonmez, Gorkem Deniz, additional
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- 2021
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26. Sesame (Sesamum indicum L.)
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Yaseen, Ghulam, primary, Ahmad, Mushtaq, additional, Zafar, Muhammad, additional, Akram, Abida, additional, Sultana, Shazia, additional, Ahmed, Sidra Nisar, additional, and Kilic, Omer, additional
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- 2021
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27. Green solvents for qualitative pharmaceutical analysis
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Yaseen, Ghulam, primary, Ahmad, Mushtaq, additional, Akram, Abida, additional, Zafar, Muhammad, additional, Sultana, Shazia, additional, Kilic, Omer, additional, and Hussain, Amir, additional
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- 2021
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28. Contributors
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Abbas, Ali, primary, Abdullah, Mohd Azmuddin, additional, Adaka, Ifeyinwa C., additional, Aguiar, F.S., additional, Aguiar, I.Q.S., additional, Ahmad, Mushtaq, additional, Aires, Giselle Cristine Melo, additional, Akbar, Nisar, additional, Akram, Abida, additional, Al Otaibi, Ahmed, additional, Albericio, Fernando, additional, Ali, Shifaqat, additional, Alshajrawi, Omar Mahmoud Said, additional, Bhat, Aamir H., additional, Camperi, Silvia A., additional, Cardillo, Alejandra B., additional, de Carvalho, Raul Nunes, additional, Cascone, Osvaldo, additional, Cheikhyoussef, Ahmad, additional, Cheikhyoussef, Natascha, additional, Chong, Gun Hean, additional, da Costa, Wanessa Almeida, additional, da Silva, Ivonete Quaresma, additional, da Silva Martins, Luiza Helena, additional, Ferreira, Maria Caroline Rodrigues, additional, Gazal, Umaima, additional, Giudicessi, Silvana L., additional, Gonçalves, Sandra, additional, Haque, Ashanul, additional, Hussain, Amir, additional, Hussain, Erum Akbar, additional, Hussein, Hanaa Ali, additional, Khan, Imran, additional, Khan, Mohd Wajid Ali, additional, Kilic, Omer, additional, Kumaravel, Sangeetha, additional, Kundu, Subrata, additional, Lee, Sin Yee, additional, Martínez Ceron, María C., additional, Menezes, Eduardo Gama Ortiz, additional, Naqvi, Syed Ali Raza, additional, de Oliveira, Joicy Corrêa, additional, Pathak, Vishal, additional, Phukan, Parmita, additional, Pinto, A.S.O., additional, Pires, Flávia Cristina Seabra, additional, Ribeiro, Thatiana Mendonça, additional, Rogez, H.L.G., additional, Romano, Anabela, additional, Saavedra, Soledad L., additional, Sarma, Diganta, additional, Shah, Syed Muhammad Ali, additional, Sonmez, Gorkem Deniz, additional, de Souza e Silva, Ana Paula, additional, Sultana, Shazia, additional, Teixeira, L.E.O., additional, Thiruvengetam, Prabaharan, additional, Uzor, Philip F., additional, Yaseen, Ghulam, additional, and Zafar, Muhammad, additional
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- 2021
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29. Micro and Macroscopic Characterization of Traded Nigella sativa Seeds Using Applied Systematics Techniques
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Rashid, Sofia, primary, Zafar, Muhammad, additional, Ahmad, Mushtaq, additional, Sultana, Shazia, additional, Ahmed, Sidra Nisar, additional, and Kilic, Omer, additional
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- 2020
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30. Supporting Clinical Decisions with Rapid Molecular Diagnostic Pneumonia Panel in Pediatric Intensive Care Unit: Single Center Experience in Turkiye
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Bozan, Gurkan, primary, Kara, Yalcin, additional, Kiral, Eylem, additional, Kizil, Mahmut Can, additional, Kacmaz, Ebru, additional, Us, Tercan, additional, Durmaz, Gul, additional, Kilic, Omer, additional, and Dinleyici, Ener Cagri, additional
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- 2023
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31. Comparison of Bordetella pertussis Antibody Levels in Pregnant Women and Umbilical Cord Blood: A Multicenter Study.
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Nepesov, Merve Iseri, Kilic, Halime, Yildirim, Sukran, Gulec, Sevgi, Kara, Yalcin, Kizil, Mahmut Can, Karbuz, Adem, Terek, Demet, Sutcu, Murat, Tufan, Ergun, Dinleyici, Meltem, Kurugol, Zafer, Kilic, Omer, and Dinleyici, Ener Cagri
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- 2024
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32. Analysis of Intestinal and Nasopharyngeal Microbiota of Children with Meningococcemia in Pediatric Intensive Care Unit: INMACS-PICU Study
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Bozan, Gurkan, primary, Pérez-Brocal, Vicente, additional, Aslan, Kaan, additional, Kiral, Eylem, additional, Sevketoglu, Esra, additional, Uysal Yazici, Mutlu, additional, Azapagasi, Ebru, additional, Kendirli, Tanil, additional, Emeksiz, Serhat, additional, Dursun, Oguz, additional, Yildizdas, Dincer, additional, Anil, Ayse Berna, additional, Akcay, Nihal, additional, Kihtir, Hasan Serdar, additional, Havan, Merve, additional, Ulgen Tekerek, Nazan, additional, Ekinci, Faruk, additional, Kilic, Omer, additional, Moya, Andres, additional, and Dinleyici, Ener Cagri, additional
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- 2023
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33. Synthesis, Characterization, and Biological Activities of Ag-Au Nanoparticles Using Heliotropium eichwaldiL. Extract as a Reducing and Stabilizing Agent
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Sher, Naila, Ahmed, Mushtaq, Mushtaq, Nadia, and Kilic, Omer
- Abstract
Green nanotechnology has gained significant attention recently in a variety of industries. Its focus is on producing nanoparticles (NPs) of a small size. It is also less harmful to human health and the environment. In Pakistan, Heliotropium eichwaldi(HE), a herbaceous plant, is extensively found. Many therapeutic qualities have been reported for the genus Heliotropium. The herb has been traditionally used to treat ulcers, headaches, and earaches. The purpose of this work is to create a simple and reliable process for the synthesis of Ag/Au bimetallic NPs (Ag-Au NPs) using HE extracts. After that, the effects of Ag-Au NPs will be examined, including their ability to scavenge free radicals and inhibit the two enzymes, acetylcholinesterase (AChE) and alpha-amylase (α-amylase). The Ag-Au NPs were characterized using FT-IR, XRD, EDX, SEM, and UV–visible spectroscopy. The Ag, Au, and Ag-Au bimetallic NPs underwent XRD analysis, which showed a face-centered cubic crystal structure with an average size of 6 nm. Ag-Au NPs exhibit rod-shaped morphologies, according to SEM. Of the Ag-Au NPs, the elemental Ag signal was 4.20% and the elemental Au signal was 26.65%. The Ag-Au NPs showed remarkable inhibitory activity against AChE, α-amylase, and free radicals. According to our research, Ag-Au NPs can be successfully generated and go on to become important antioxidant, antidiabetic, and anti-Alzheimer agent compounds. Nonetheless, more research is advised to reduce any possible hazards.
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- 2024
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34. Comparison of Bordetella pertussisAntibody Levels in Pregnant Women and Umbilical Cord Blood: A Multicenter Study
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Iseri Nepesov, Merve, Kilic, Halime, Yildirim, Sukran, Gulec, Sevgi, Kara, Yalcin, Kizil, Mahmut Can, Karbuz, Adem, Terek, Demet, Sutcu, Murat, Tufan, Ergun, Dinleyici, Meltem, Kurugol, Zafer, Kilic, Omer, and Dinleyici, Ener Cagri
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- 2024
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35. Pollen Micromorphology among Amaranthaceous Species from Desert Rangeland: Exine Stratification and their Taxonomic Significance
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Majeed, Salman, primary, Ahmad, Mushtaq, additional, Ali, Alamdar, additional, Althobaiti, Ashwaq T., additional, Ramadan, Mohamed Fawzy, additional, Kilic, Omer, additional, Demirpolat, Azize, additional, Çobanoğlu, Duygu Nur, additional, Zafar, Sadia, additional, Afza, Rabia, additional, Makhkamov, Trobjon, additional, Yuldashev, Akramjon, additional, Gafforov, Yusufjon, additional, Khaydarov, Khislat, additional, Zafar, Muhammad, additional, and Sultana, Shazia, additional
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- 2023
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36. Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
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Lee, Danyel, Le Pen, Jérémie, Yatim, Ahmad, Dong, Beihua, Aquino, Yann, Ogishi, Masato, Pescarmona, Rémi, Talouarn, Estelle, Rinchai, Darawan, Zhang, Peng, Perret, Magali, Liu, Zhiyong, Jordan, Iolanda, Elmas Bozdemir, Sefika, Bayhan, Gulsum Iclal, Beaufils, Camille, Bizien, Lucy, Bisiaux, Aurelie, Lei, Weite, Hasan, Milena, Chen, Jie, Gaughan, Christina, Asthana, Abhishek, Libri, Valentina, Luna, Joseph, Jaffré, Fabrice, Hoffmann, H.-Heinrich, Michailidis, Eleftherios, Moreews, Marion, Seeleuthner, Yoann, Bilguvar, Kaya, Mane, Shrikant, Flores, Carlos, Zhang, Yu, Arias, Andrés, Bailey, Rasheed, Schlüter, Agatha, Milisavljevic, Baptiste, Bigio, Benedetta, Le Voyer, Tom, Materna, Marie, Gervais, Adrian, Moncada-Velez, Marcela, Pala, Francesca, Lazarov, Tomi, Levy, Romain, Neehus, Anna-Lena, Rosain, Jérémie, Peel, Jessica, Chan, Yi-Hao, Morin, Marie-Paule, Pino-Ramirez, Rosa Maria, Belkaya, Serkan, Lorenzo, Lazaro, Anton, Jordi, Delafontaine, Selket, Toubiana, Julie, Bajolle, Fanny, Fumadó, Victoria, Dediego, Marta, Fidouh, Nadhira, Rozenberg, Flore, Pérez-Tur, Jordi, Chen, Shuibing, Evans, Todd, Geissmann, Frédéric, Lebon, Pierre, Weiss, Susan, Bonnet, Damien, Duval, Xavier, Pan-Hammarström, Qiang, Planas, Anna, Meyts, Isabelle, Haerynck, Filomeen, Pujol, Aurora, Sancho-Shimizu, Vanessa, Dalgard, Clifford, Bustamante, Jacinta, Puel, Anne, Boisson-Dupuis, Stéphanie, Boisson, Bertrand, Maniatis, Tom, Zhang, Qian, Bastard, Paul, Notarangelo, Luigi, Béziat, Vivien, Perez de Diego, Rebeca, Rodriguez-Gallego, Carlos, Su, Helen, Lifton, Richard, Jouanguy, Emmanuelle, Cobat, Aurélie, Alsina, Laia, Keles, Sevgi, Haddad, Elie, Abel, Laurent, Belot, Alexandre, Quintana-Murci, Lluis, Rice, Charles, Silverman, Robert, Zhang, Shen-Ying, Casanova, Jean-Laurent, Alavoine, Loubna, Behillil, Sylvie, Burdet, Charles, Charpentier, Charlotte, Dechanet, Aline, Descamps, Diane, Ecobichon, Jean-Luc, Enouf, Vincent, Frezouls, Wahiba, Houhou, Nadhira, Kafif, Ouifiya, Lehacaut, Jonathan, Letrou, Sophie, Lina, Bruno, Lucet, Jean-Christophe, Manchon, Pauline, Nouroudine, Mariama, Piquard, Valentine, Quintin, Caroline, Thy, Michael, Tubiana, Sarah, van der Werf, Sylvie, Vignali, Valérie, Visseaux, Benoit, Yazdanpanah, Yazdan, Chahine, Abir, Waucquier, Nawal, Migaud, Maria-Claire, Deplanque, Dominique, Djossou, Félix, Mergeay-Fabre, Mayka, Lucarelli, Aude, Demar, Magalie, Bruneau, Léa, Gérardin, Patrick, Maillot, Adrien, Payet, Christine, Laviolle, Bruno, Laine, Fabrice, Paris, Christophe, Desille-Dugast, Mireille, Fouchard, Julie, Malvy, Denis, Nguyen, Duc, Pistone, Thierry, Perreau, Pauline, Gissot, Valérie, Le Goas, Carole, Montagne, Samatha, Richard, Lucie, Chirouze, Catherine, Bouiller, Kévin, Desmarets, Maxime, Meunier, Alexandre, Lefèvre, Benjamin, Jeulin, Hélène, Legrand, Karine, Lomazzi, Sandra, Tardy, Bernard, Gagneux-Brunon, Amandine, Bertholon, Frédérique, Botelho-Nevers, Elisabeth, Christelle, Kouakam, Nicolas, Leturque, Roufai, Layidé, Amat, Karine, Couffin-Cadiergues, Sandrine, Espérou, Hélène, Hendou, Samia, Abolhassani, Hassan, Aguilera-Albesa, Sergio, Aiuti, Alessandro, Akcan, Ozge Metin, Akcay, Nihal, Alkan, Gulsum, Alkhater, Suzan, Allende, Luis Miguel, Alper, Yosunkaya, Amenzoui, Naima, Anderson, Mark, Arkin, Lisa, Aubart, Melodie, Avramenko, Iryna, Aydemir, Şehnaz, Gayretli Aydin, Zeynep Gökçe, Aytekin, Caner, Aytekin, Gökhan, Erol Aytekin, Selma, Bando, Silvia Yumi, Beland, Kathie, Biggs, Catherine, Bilbao Aburto, Agurtzane, Blanchard-Rohner, Geraldine, Blázquez-Gamero, Daniel, Bloomfield, Marketa, Bogunovic, Dusan, Bondarenko, Anastasia, Borghesi, Alessandro, Bousfiha, Amed Aziz, Boyarchuk, Oksana, Brodin, Petter, Bryceson, Yenan, Bucciol, Giorgia, Calcaterra, Valeria, Casari, Giorgio, Cavalcanti, Andre, Celik, Jale Bengi, Chrousos, George, Colobran, Roger, Condino-Neto, Antonio, Conti, Francesca, Cooper, Megan, Coskuner, Taner, Cyrus, Cyril, D’auria, Enza, Drolet, Beth, Bursal Duramaz, Burcu, El Zein, Loubna, Elnagdy, Marwa, Emiroglu, Melike, Erdeniz, Emine Hafize, Fabi, Marianna, Baris Feldman, Hagit, Fellay, Jacques, Fencl, Filip, Filippatos, Filippos, Freiss, Julie, Fremuth, Jiri, Gagro, Alenka, Garcia-Solis, Blanca, Vergine, Gianluca, González-Montelongo, Rafaela, Gul, Yahya, Gülhan, Belgin, Gultekin, Sara Sebnem Kilic, Gut, Marta, Halwani, Rabih, Hammarström, Lennart, Hatipoğlu, Nevin, Heath, James, Henrickson, Sarah, Hernandez-Brito, Elisa, Hoffman, Ilse, Hoste, Levi, Hsieh, Elena, Íñigo-Campos, Antonio, Itan, Yuval, Jabandziev, Petr, Kandemir, Bahar, Kanık-Yüksek, Saliha, Kapakli, Hasan, Karbuz, Adem, Kasapcopur, Ozgur, Kechiche, Robin, Kendir Demirkol, Yasemin, Kilic, Omer, Hansen, Stella Kim, Klocperk, Adam, Lau, Yu-Lung, Lebl, Jan, Lorenzo-Salazar, José, Lucas, Carrie, Maglorius, Majistor, Marque, Laura, Novoa Medina, Yeray, Montesdeoca Melián, Abián, Mentis, Alexios-Fotios, Pato, Michele, Michos, Athanasios, Milner, Joshua, Mogensen, Trine, Muñoz-Barrera, Adrián, Nepesov, Serdar, Farela Neves, João, Ng, Ashley, Ng, Lisa, Novelli, Antonio, Novelli, Giuseppe, Oz, Fatma Nur, Ocejo-Viñals, J. Gonzalo, Okada, Satoshi, Orbak, Zerrin, Kilic, Ahmet Osman, Ouair, Hind, Öz, Şadiye Kübra Tüter, Özçelik, Tayfun, Özkan, Esra Akyüz, Parlakay, Aslınur Özkaya, Pato, Carlos, Paz-Artal, Estela, Pelham, Simon, Pellier, Isabelle, Philippot, Quentin, Planas-Serra, Laura, Plassart, Samira, Pokorna, Petra, Polat, Meltem, Poli, Cecilia, Prando, Carolina, Renia, Laurent, Rivière, Jacques, Rodríguez-Palmero, Agustí, Roussel, Lucie, Rubio-Rodriguez, Luis, Salifu, Moro, Sasek, Lumir, Sasia, Laura, Scherbina, Anna, Schmitt, Erica, Sediva, Anna, Sevketoglu, Esra, Slaba, Katerina, Slaby, Ondrej, Sobh, Ali, Solé-Violán, Jordi, Soler-Palacin, Pere, de Somer, Lien, Sözeri, Betül, Spaan, András, Stepanovskiy, Yuriy, Tangye, Stuart, Tanir, Gonul, Tatsi, Elizabeth Barbara, Thorball, Christian, Hancerli Torun, Selda, Turvey, Stuart, Uddin, Mohammed, Uyar, Emel, Valencia-Ramos, Juan, van den Rym, Ana Maria, Vatansev, Hulya, Castillo de Vera, Martín, Vermeulen, François, Vinh, Donald, Volokha, Alla, von Bernuth, Horst, Wouters, Carine, Yahşi, Aysun, Yarar, Volkan, Yesilbas, Osman, Yıldız, Mehmet, Zatz, Mayana, Zawadzki, Pawel, Zuccotti, Gianvincenzo, Rockefeller University [New York], Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Génomique évolutive, modélisation et santé (GEMS), Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de référence des rhumatismes inflammatoires et maladies auto-immunes systémiques rares de l’enfant / National Referee Centre for Rheumatic and AutoImmune and Systemic Diseases in Children [Lyon] (RAISE), Hospices Civils de Lyon (HCL), Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Génétique Physiologie et Systèmes d'Elevage (GenPhySE ), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-École nationale supérieure agronomique de Toulouse (ENSAT), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Sidra Medicine [Doha, Qatar], BIOASTER Technology Research Institute, Lyon, France, St. Giles Laboratory of Human Genetics of Infectious Diseases, Department of Paediatrics and Intensive Care, Hospital Universitari Sant Joan de Deu, Human genetics of infectious diseases : Mendelian predisposition (Equipe Inserm U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Département de Pédiatrie et maladies infectieuses [CHU Necker], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Génétique Evolutive Humaine - Human Evolutionary Genetics, Centre de Recherche Translationnelle - Center for Translational Science (CRT), Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), Shanghai Jiaotong University, Sheffield Hallam University, Institut Jean Lamour (IJL), Institut de Chimie du CNRS (INC)-Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Institut Pasteur [Paris] (IP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Centre d'investigation Clinique [CHU Bichat] - Épidémiologie clinique (CIC 1425), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Biodiversité et Epidémiologie des Bactéries pathogènes - Biodiversity and Epidemiology of Bacterial Pathogens, Centre d'Investigation Clinique - Innovation Technologique de Lille - CIC 1403 - CIC 9301 (CIC Lille), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane), Université des Antilles et de la Guyane (UAG)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pointe-à-Pitre/Abymes [Guadeloupe] -CHU de Fort de France-Centre Hospitalier Andrée Rosemon [Cayenne, Guyane Française], Centre d'Investigation Clinique de La Réunion - INSERM (CIC 1410), Université de La Réunion (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), Centre d'Investigation Clinique [Rennes] (CIC), Université de Rennes (UR)-Hôpital Pontchaillou-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], The Laboratory of Human Genetics of Infectious Diseases is supported by the Howard Hughes Medical Institute, the Rockefeller University, the St. Giles Foundation, the National Institutes of Health (NIH) (R01AI088364 and R21AI160576), the National Center for Advancing Translational Sciences (NCATS), NIH Clinical and Translational Science Award (CTSA) program (UL1TR001866), the Yale Center for Mendelian Genomics and the GSP Coordinating Center funded by the National Human Genome Research Institute (NHGRI) (UM1HG006504 and U24HG008956), the Yale High-Performance Computing Center (S10OD018521), the Fisher Center for Alzheimer’s Research Foundation, the Meyer Foundation, the JBP Foundation, the French National Research Agency (ANR) under the 'Investments for the Future' program (ANR-10-IAHU-01), the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence (ANR-10-LABX-62-IBEID), the French Foundation for Medical Research (FRM) (EQU201903007798), the ANR GenMISC (ANR-21-COVR-039), the ANRS-COV05, ANR GENVIR (ANR-20-CE93-003) and ANR AABIFNCOV (ANR-20-CO11-0001) projects, the ANR-RHU program (ANR-21-RHUS-08), the European Union’s Horizon 2020 research and innovation program under grant agreement 824110 (EASI-genomics), the HORIZON-HLTH-2021-DISEASE-04 program under grant agreement 01057100 (UNDINE), the ANR-RHU Program ANR-21-RHUS-08 (COVIFERON), the Square Foundation, Grandir – Fonds de solidarité pour l’enfance, the Fondation du Souffle, the SCOR Corporate Foundation for Science, the French Ministry of Higher Education, Research, and Innovation (MESRI-COVID-19), Institut National de la Santé et de la Recherche Médicale (INSERM), and Paris Cité University. We acknowledge support from the National Institute of Allergy and Infectious Diseases (NIAID) of the NIH under award R01AI104887 to R.H.S. and S.R.W. The Laboratory of Human Evolutionary Genetics (Institut Pasteur) is supported by the Institut Pasteur, the Collège de France, the French Government’s Investissement d’Avenir program, Laboratoires d’Excellence 'Integrative Biology of Emerging Infectious Diseases' (ANR-10-LABX-62-IBEID) and 'Milieu Intérieur' (ANR-10-LABX-69-01), the Fondation de France (no. 00106080), the FRM (Equipe FRM DEQ20180339214 team), and the ANR COVID-19-POPCELL (ANR-21-CO14-0003-01). A.Puj. is supported by ACCI20-759 CIBERER, EasiGenomics H2020 Marató TV3 COVID 2021-31-33, the HORIZON-HLTH-2021-ID: 101057100 (UNDINE), the Horizon 2020 program under grant no. 824110 (EasiGenomics grant no. COVID-19/PID12342), and the CERCA Program/Generalitat de Catalunya. The Canarian Health System sequencing hub was funded by the Instituto de Salud Carlos III (COV20_01333 and COV20_01334), the Spanish Ministry of Science and Innovation (RTC-2017-6471-1, AEI/FEDER, UE), Fundación MAPFRE Guanarteme (OA21/131), and Cabildo Insular de Tenerife (CGIEU0000219140 and 'Apuestas científicas del ITER para colaborar en la lucha contra la COVID-19'). The CoV-Contact Cohort was funded by the French Ministry of Health and the European Commission (RECOVER project). Our studies are also funded by the Ministry of Health of the Czech Republic Conceptual Development of Research Organization (FNBr, 65269705) and ANID COVID0999 funding in Chile. G. Novelli and A. Novelli are supported by Regione Lazio (Research Group Projects 2020) No. A0375-2020-36663, GecoBiomark. A.M.P., M.L.D., and J.P.-T. are supported by the Inmungen-CoV2 project of CSIC. This work was supported in part by the Intramural Research Program of the NIAID, NIH. The research work of A.M.P, M.L.D., and J.P.-T. was funded by the European Commission –NextGenerationEU (Regulation EU 2020/2094), through CSIC’s Global Health Platform (PTI Salud Global). I.M. is a senior clinical investigator at FWO Vlaanderen supported by a VIB GC PID grant, by FWO grants G0B5120N (DADA2) and G0E8420N, and by the Jeffrey Modell Foundation. I.M. holds an ERC-StG MORE2ADA2 grant and is also supported by ERN-RITA. A.Y. is supported by fellowships from the European Academy of Dermatology and Venereology and the Swiss National Science Foundation and by an Early Career Award from the Thrasher Research Fund. Y.-H.C. is supported by an A*STAR International Fellowship (AIF). M.O. was supported by the David Rockefeller Graduate Program, the New York Hideyo Noguchi Memorial Society (HNMS), the Funai Foundation for Information Technology (FFIT), the Honjo International Scholarship Foundation (HISF), and the National Cancer Institute (NCI) F99 Award (F99CA274708). A.A.A. was supported by Ministerio de Ciencia Tecnología e Innovación MINCIENCIAS, Colombia (111584467551/CT 415-2020). D.L. is supported by a fellowship from the FRM for medical residents and fellows. E.H. received funding from the Bank of Montreal Chair of Pediatric Immunology, Foundation of CHU Sainte-Justine, CIHR grants PCC-466901 and MM1-181123, and a Canadian Pediatric Society IMPACT study. Q.P.-H. received funding from the European Union’s Horizon 2020 research and innovation program (ATAC, 101003650), the Swedish Research Council, and the Knut and Alice Wallenberg Foundation. Work in the Laboratory of Virology and Infectious Disease was supported by NIH grants P01AI138398-S1, 2U19AI111825, R01AI091707-10S1, and R01AI161444, a George Mason University Fast Grant, the G. Harold and Leila Y. Mathers Charitable Foundation, the Meyer Foundation, and the Bawd Foundation. R.P.L. is on the board of directors of both Roche and the Roche subsidiary Genentech. J.L.P. was supported by a Francois Wallace Monahan Postdoctoral Fellowship at the Rockefeller University and by a European Molecular Biology Organization Long-Term Fellowship (ALTF 380-2018)., ANR-10-IAHU-0001,Imagine,Institut Hospitalo-Universitaire Imagine(2010), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-21-COVR-0039,GenMIS-C,Recherche des Déficits immunitaires innées monogéniques prédisposant au syndrome inflammatoire multisystémique chez l'enfant.(2021), ANR-20-CE93-0003,GENVIR,Analyse multi-omique de l'immunité anti-virale: de l'identification des circuits biologiques pertinents à la découverte de défauts monogéniques héréditaires de l'immunité chez les patients avec infections virales sévères(2020), ANR-20-CO11-0001,AABIFNCOV,Bases génétiques et immunologiques des auto-anticorps contre les interférons de type I prédisposant aux formes sévères de COVID-19.(2020), ANR-21-RHUS-0008,COVIFERON,Covid-19 and interferons: from discovery to therapy(2021), ANR-10-LABX-0069,MILIEU INTERIEUR,GENETIC & ENVIRONMENTAL CONTROL OF IMMUNE PHENOTYPE VARIANCE: ESTABLISHING A PATH TOWARDS PERSONALIZED MEDICINE(2010), ANR-21-CO14-0003,COVID-19-POPCELL,Facteurs génétiques et infectieux à l'origine de la variabilité populationnelle de la réponse immunitaire à l'infection par le SARS-CoV-2(2021), European Project: 824110,H2020-INFRAIA-2018-1,EASI-Genomics(2019), European Project: 101057100,UNDINE, Howard Hughes Medical Institute, Rockefeller University, St. Giles Foundation, National Institutes of Health (US), Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación (España), Fundación Mapfre, Cabildo de Tenerife, Fundació La Marató de TV3, Centro de Investigación Biomédica en Red Enfermedades Raras (España), Consejo Superior de Investigaciones Científicas (España), European Commission, and Pérez-Tur, Jordi
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Multidisciplinary ,Settore MED/03 ,[SDV]Life Sciences [q-bio] ,Medicine and Health Sciences ,CoV-Contact Cohort§ - Abstract
62 páginas, 5 figuras, 2 tablas, Multisystem inflammatory syndrome in children (MIS-C) is a rare and severe condition that follows benign COVID-19. We report autosomal recessive deficiencies of OAS1, OAS2, or RNASEL in five unrelated children with MIS-C. The cytosolic double-stranded RNA (dsRNA)-sensing OAS1 and OAS2 generate 2'-5'-linked oligoadenylates (2-5A) that activate the single-stranded RNA-degrading ribonuclease L (RNase L). Monocytic cell lines and primary myeloid cells with OAS1, OAS2, or RNase L deficiencies produce excessive amounts of inflammatory cytokines upon dsRNA or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stimulation. Exogenous 2-5A suppresses cytokine production in OAS1-deficient but not RNase L-deficient cells. Cytokine production in RNase L-deficient cells is impaired by MDA5 or RIG-I deficiency and abolished by mitochondrial antiviral-signaling protein (MAVS) deficiency. Recessive OAS-RNase L deficiencies in these patients unleash the production of SARS-CoV-2-triggered, MAVS-mediated inflammatory cytokines by mononuclear phagocytes, thereby underlying MIS-C, The Laboratory of Human Genetics of Infectious Diseases is supported by the Howard Hughes Medical Institute, the Rockefeller University, the St. Giles Foundation, the National Institutes of Health (NIH) (R01AI088364 and R21AI160576), the National Center for Advancing Translational Sciences (NCATS), NIH Clinical and Translational Science Award (CTSA) program (UL1TR001866), the Yale Center for Mendelian Genomics and the GSP Coordinating Center funded by the National Human Genome Research Institute (NHGRI) (UM1HG006504 and U24HG008956), the Yale High-Performance Computing Center (S10OD018521), the Fisher Center for Alzheimer’s Research Foundation, the Meyer Foundation, the JBP Foundation, the French National Research Agency (ANR) under the “Investments for the Future” program (ANR-10-IAHU-01), the Integrative Biology of Emerging Infectious Diseases Laboratory of Excellence (ANR-10- LABX-62-IBEID), the French Foundation for Medical Research (FRM) (EQU201903007798), the ANR GenMISC (ANR-21-COVR-039), the ANRS-COV05, ANR GENVIR (ANR-20-CE93-003) and ANR AABIFNCOV (ANR-20-CO11-0001) projects, the ANR-RHU program (ANR-21-RHUS-08), the European Union’s Horizon 2020 research and innovation program under grant agreement 824110 (EASI-genomics), the HORIZON-HLTH-2021-DISEASE-04 program under grant agreement 01057100 (UNDINE), the ANR-RHU Program ANR-21- RHUS-08 (COVIFERON), the Square Foundation, Grandir – Fonds de solidarité pour l’enfance, the Fondation du Souffle, the SCOR Corporate Foundation for Science, the French Ministry of Higher Education, Research, and Innovation (MESRI-COVID-19), Institut National de la Santé et de la Recherche Médicale (INSERM), and Paris Cité University. We acknowledge support from the National Institute of Allergy and Infectious Diseases (NIAID) of the NIH under award R01AI104887 to R.H.S. and S.R.W. The Laboratory of Human Evolutionary Genetics (Institut Pasteur) is supported by the Institut Pasteur, the Collège de France, the French Government’s Investissement d’Avenir program, Laboratoires d’Excellence “Integrative Biology of Emerging Infectious Diseases” (ANR-10-LABX-62-IBEID) and “Milieu Intérieur” (ANR-10-LABX-69-01), the Fondation de France (no. 00106080), the FRM (Equipe FRM DEQ20180339214 team), and the ANR COVID-19-POPCELL (ANR-21-CO14-0003-01). A.Puj. is supported by ACCI20-759 CIBERER, EasiGenomics H2020 Marató TV3 COVID 2021-31-33, the HORIZON-HLTH-2021-ID: 101057100 (UNDINE), the Horizon 2020 program under grant no. 824110 (EasiGenomics grant no. COVID-19/PID12342), and the CERCA Program/Generalitat de Catalunya. The Canarian Health System sequencing hub was funded by the Instituto de Salud Carlos III (COV20_01333 and COV20_01334), the Spanish Ministry of Science and Innovation (RTC-2017-6471-1; AEI/FEDER, UE), Fundación MAPFRE Guanarteme (OA21/131), and Cabildo Insular de Tenerife (CGIEU0000219140 and “Apuestas científicas del ITER para colaborar en la lucha contra la COVID-19”). The CoV-Contact Cohort was funded by the French Ministry of Health and the European Commission (RECOVER project). Our studies are also funded by the Ministry of Health of the Czech Republic Conceptual Development of Research Organization (FNBr, 65269705) and ANID COVID0999 funding in Chile. G. Novelli and A. Novelli are supported by Regione Lazio (Research Group Projects 2020) No. A0375-2020-36663, GecoBiomark. A.M.P., M.L.D., and J.P.-T. are supported by the Inmungen-CoV2 project of CSIC. This work was supported in part by the Intramural Research Program of the NIAID, NIH. The research work of A.M..P, M.L.D., and J.P.-T. was funded by the European Commission –NextGenerationEU (Regulation EU 2020/2094), through CSIC’s Global Health Platform (PTI Salud Global). I.M. is a senior clinical investigator at FWO Vlaanderen supported by a VIB GC PID grant, by FWO grants G0B5120N (DADA2) and G0E8420N, and by the Jeffrey Modell Foundation. I.M. holds an ERC-StG MORE2ADA2 grant and is also supported by ERN-RITA. A.Y. is supported by fellowships from the European Academy of Dermatology and Venereology and the Swiss National Science Foundation and by an Early Career Award from the Thrasher Research Fund. Y.-H.C. is supported by an A*STAR International Fellowship (AIF). M.O. was supported by the David Rockefeller Graduate Program, the New York Hideyo Noguchi Memorial Society (HNMS), the Funai Foundation for Information Technology (FFIT), the Honjo International Scholarship Foundation (HISF), and the National Cancer Institute (NCI) F99 Award (F99CA274708). A.A.A. was supported by Ministerio de Ciencia Tecnología e Innovación MINCIENCIAS, Colombia (111584467551/CT 415-2020). D.L. is supported by a fellowship from the FRM for medical residents and fellows. E.H. received funding from the Bank of Montreal Chair of Pediatric Immunology, Foundation of CHU Sainte-Justine, CIHR grants PCC-466901 and MM1-181123, and a Canadian Pediatric Society IMPACT study. Q.P.-H. received funding from the European Union’s Horizon 2020 research and innovation program (ATAC, 101003650), the Swedish Research Council, and the Knut and Alice Wallenberg Foundation. Work in the Laboratory of Virology and Infectious Disease was supported by NIH grants P01AI138398-S1, 2U19AI111825, R01AI091707-10S1, and R01AI161444; a George Mason University Fast Grant; the G. Harold and Leila Y. Mathers Charitable Foundation; the Meyer Foundation; and the Bawd Foundation. R.P.L. is on the board of directors of both Roche and the Roche subsidiary Genentech. J.L.P. was supported by a Francois Wallace Monahan Postdoctoral Fellowship at the Rockefeller University and by a European Molecular Biology Organization Long-Term Fellowship (ALTF 380-2018).
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- 2023
37. Prevalence of Anosmia in 10.157 Pediatric COVID-19 Cases: Multicenter Study from Turkey
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Ciftdogan, Dilek Yilmaz, Demirbuga, Asuman, Gungor, Emre, Aygun, Fatma Deniz, Sahinkaya, Sahika, Bulbul, Lida, Uysalol, Metin, Cura Yayla, Burcu Ceylan, Aykac, Kubra, Tekin, Ayse, Caglar, Ilknur, Ozdem, Suna, Ozcan, Nur, Bilen, Nimet Melis, Buyukcam, Ayse, Kara, Ates, Turgut, Mehmet, Kurugol, Zafer, Cokugras, Haluk Cezmi, Devrim, Ilker, Belet, Nursen, Ciftci, Ergin, Alabaz, Derya, Kilic, Omer, Oncel, Selim, Aksay, Ahu Kara, Torun, Selda Hancerli, Ozsurekci, Yasemin, Bal, Zumrut Sahbudak, Tekin, Deniz, Kocabas, Bilge Aldemir, Turel, Ozden, Ozer, Arife, Uygun, Hatice Uyanik, Umit, Zuhal, Bolat, Ahmet, Kara, Manolya, Sutcu, Murat, Yesil, Edanur, Arikan, Kamile, Genceli, Mustafa, Vatansever, Goksel, Akca, Mehtap, Ozmen, Berfin Ozgokce, Sahin, Emre, Dogan, Yunus Emre, Guney, Ahmet Yasin, Mustafaoglu, Ozlem, Kara, Soner Sertan, Cukurova, Ibrahim, Teksam, Ozlem, Apaydin, Gozde, Cem, Ela, Demir, Tugba, Sen, Semra Bayturan, Bal, Alkan, Bursal-Duramaz, Burcu, Polat, MELTEM, Akcan, Ozge Metin, Elmas-Bozdemir, Sefika, Egil, Oguz, Ozdemir, Halil, Kuyucu, Necdet, Ozdem-Alatas, Silem, Hacimustafaoglu, Mustafa, Gulhan, Belgin, Kanik-Yuksek, Saliha, Kiran, Sibel, Karadag-Oncel, Eda, Elvan-Tuz, Aysegul, Cakici, Ozlem, Erdeniz, Emine Hafize, Ozkan, Esra Akyuz, Basaranoglu, Sevgen Tanir, Dayar, Gulperi Timurtas, Kosker, Muhammet, Kara, Yalcin, Kizil, Mahmut Can, Celik, Taylan, Cay, Ummuhan, Cetin, Ceren, Karaaslan, Ayse, and Cetin, Benhur Sirvan
- Subjects
Microbiology (medical) ,Adult ,Adolescent ,Turkey ,SARS-CoV-2 ,Anosmia ,COVID-19 ,Cohort Studies ,Infectious Diseases ,Pediatrics, Perinatology and Child Health ,Prevalence ,Humans ,Prospective Studies ,Ageusia ,Child - Abstract
Introduction: COVID-19-related anosmia is a remarkable and disease-specific finding. With this multicenter cohort study, we aimed to determine the prevalence of anosmia in pediatric cases with COVID-19 from Turkey and make an objective assessment with a smell awareness questionnaire. Material and Methods: This multicenter prospective cohort study was conducted with pediatric infection clinics in 37 centers in 19 different cities of Turkey between October 2020 and March 2021. The symptoms of 10.157 COVID-19 cases 10-18 years old were examined. Age, gender, other accompanying symptoms, and clinical severity of the disease of cases with anosmia and ageusia included in the study were recorded. The cases were interviewed for the smell awareness questionnaire at admission and one month after the illness. Results: Anosmia was present in 12.5% (1.266/10.157) of COVID-19 cases 10-18 years of age. The complete records of 1053 patients followed during the study period were analyzed. The most common symptoms accompanying symptoms with anosmia were ageusia in 885 (84%) cases, fatigue in 534 cases (50.7%), and cough in 466 cases (44.3%). Anosmia was recorded as the only symptom in 84 (8%) of the cases. One month later, it was determined that anosmia persisted in 88 (8.4%) cases. In the smell awareness questionnaire, the score at admission was higher than the score one month later (P < 0.001). Discussion: With this study, we have provided the examination of a large case series across Turkey. Anosmia and ageusia are specific symptoms seen in cases of COVID-19. With the detection of these symptoms, it should be aimed to isolate COVID-19 cases in the early period and reduce the spread of the infection. Such studies are important because the course of COVID-19 in children differs from adults and there is limited data on the prevalence of anosmia.
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- 2022
38. Characterization of cord blood CD3(+)TCRV alpha 7.2(+)CD161(high) T and innate lymphoid cells in the pregnancies with gestational diabetes, morbidly adherent placenta, and pregnancy hypertension diseases
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KÜTÜK, MEHMET SERDAR, Haliloglu, Yesim, Unal, Ekrem, ULUDAĞ, Semih Zeki, ÖZCAN, ALPER, Erdem, Serife, Azizoglu, Zehra Busra, Bicer, Ayten, Ozarslan, Ozcan Yeniay, Kilic, Omer, Okus, Fatma Zehra, Demir, Fatma, CANATAN, HALİT, KARAKÜKCÜ, MUSA, EKEN, AHMET, and KÜTÜK, MEHMET SERDAR
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Haliloglu Y., ÖZCAN A., Erdem S., Azizoglu Z. B. , Bicer A., Ozarslan O. Y. , Kilic O., Okus F. Z. , Demir F., CANATAN H., et al., -Characterization of cord blood CD3(+)TCRV alpha 7.2(+)CD161(high) T and innate lymphoid cells in the pregnancies with gestational diabetes, morbidly adherent placenta, and pregnancy hypertension diseases-, AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2022 - Abstract
Problem Although pregnant women with gestational diabetes (GD), morbidly adherent placenta (MAP), and pregnancy hypertension (pHT) diseases lead to intrauterine growth restriction (IUGR), little is known about their effect on mucosal-associated invariant T (MAIT) and innate lymphoid cells (ILC) in the umbilical cord. This study aimed to quantify and characterize MAIT cells and ILCs in the cord blood of pregnant women with GD, MAP, and pHT diseases. Method of study Cord blood mononuclear cells (CBMCs) were isolated by Ficoll-Paque gradient. CD3(+)TCRV alpha 7.2(+)CD161(high) cells and ILC subsets were quantified by flow cytometry. CBMCs were stimulated with PMA/Ionomycin and Golgi Plug for 4 h and stained for IFN-gamma, TNF-alpha, and granzyme B. The stained cells were analyzed on FACS ARIA III. Results Compared with healthy pregnancies, in the cord blood of the pHT group, elevated number of lymphocytes was observed. Moreover, the absolute number of IFN-gamma producing CD4(+) or CD4(-) subsets of CD3(+)TCRV alpha 7.2(+)CD161(high) cells as well as those producing granzyme B were significantly elevated in the pHT group compared to healthy controls suggesting increased MAIT cell activity in the pHT cord blood. Similarly, in the MAP group, the absolute number of total CD3(+)TCRV alpha 7.2(+)CD161(high) cells, but not individual CD4(+) or negative subsets, were significantly increased compared with healthy controls- cord blood. Absolute numbers of total CD3(+)TCRV alpha 7.2(+)CD161(high) cells and their subsets were comparable in the cord blood of the GD group compared with healthy controls. Finally, the absolute number of total ILCs and ILC3 subset were significantly elevated in only pHT cord blood compared with healthy controls. Our data also reveal that IFN-gamma(+) or granzyme B+ cell numbers negatively correlated with fetal birth weight. Conclusions CD3(+)TCRV alpha 7.2(+)CD161(high) cells and ILCs show unique expansion and activity in the cord blood of pregnant women with distinct diseases causing IUGR and may play roles in fetal growth restriction.
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- 2022
39. Characterization of Cord Blood CD3 + TCRVα7.2 + CD161 high T and Innate Lymphoid Cells in the Pregnancies with gestational diabetes, morbidly adherent placenta, and pregnancy hypertension diseases
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Haliloglu, Yesim, primary, Ozcan, Alper, additional, Erdem, Serife, additional, Azizoglu, Zehra Busra, additional, Bicer, Ayten, additional, Ozarslan, Ozcan Yeniay, additional, Kilic, Omer, additional, Okus, Fatma Zehra, additional, Demir, Fatma, additional, Canatan, Halit, additional, Karakukcu, Musa, additional, Uludag, Semih Zeki, additional, Kutuk, M Serdar, additional, Unal, Ekrem, additional, and Eken, Ahmet, additional
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- 2022
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40. Hypophosphatemia and its clinical implications in critically ill children: A retrospective study
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Kilic, Omer, Demirkol, Demet, Ucsel, Raif, Citak, Agop, and Karabocuoglu, Metin
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- 2012
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41. Light and scanning electron microscopic observation of palynological characteristics in spinelessAstragalusL. (Fabaceae) and its taxonomic significance
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Khan, Amjad, primary, Ahmad, Mushtaq, additional, Zafar, Sadia, additional, Abbas, Qamar, additional, Arfan, Muhammad, additional, Zafar, Muhammad, additional, Sultana, Shazia, additional, Ullah, Sher Aman, additional, Khan, Siraj, additional, Akhtar, Anam, additional, Kilic, Omer, additional, and Ozdemir, Fethi Ahmet, additional
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- 2022
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42. Intestinal Microbiota Composition of Children with Infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) and Multisystem Inflammatory Syndrome (MIS-C)
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SUSKUN, Cansu, primary, KILIC, Omer, additional, GUVEN, Sirin, additional, KARBUZ, Adem, additional, KARA, Yalcın, additional, KACMAZ, Ebru, additional, SAHIN, Aslihan, additional, BOGA, Aysun, additional, GULHAN, Belgin, additional, KIRAL, Eylem, additional, BOZAN, Gurkan, additional, ARSLANOGLU, Mehmet Ozgür, additional, KIZIL, Mahmut Can, additional, DINLEYICI, Meltem, additional, US, Tercan, additional, VARIS, Ahmet, additional, KAYA, Mucahit, additional, VANDENPLAS, Yvan, additional, and DINLEYICI, Ener Cagri, additional
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- 2022
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43. Multisystem inflammatory syndrome in children associated with COVID ‐19 in 101 cases from Turkey ( Turk‐MISC study)
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Yilmaz Ciftdogan, Dilek, primary, Ekemen Keles, Yildiz, additional, Karbuz, Adem, additional, Cetin, Benhur Sirvan, additional, Elmas Bozdemir, Sefika, additional, Kepenekli Kadayifci, Eda, additional, Metin Akcan, Ozge, additional, Ozer, Arife, additional, Erat, Tugba, additional, Sutcu, Murat, additional, Buyukcam, Ayse, additional, Belet, Nursen, additional, Erdeniz, Emine Hafize, additional, Dalgic Karabulut, Nazan, additional, Hancerli Torun, Selda, additional, Oncel, Selim, additional, Orbak, Zerrin, additional, Turel, Ozden, additional, Gayretli Aydin, Zeynep Gokce, additional, Kilic, Omer, additional, Yahsi, Aysun, additional, Kara Aksay, Ahu, additional, Ergenc, Zeynep, additional, Petmezci, Mey Talip, additional, Oflaz, Mehmet Burhan, additional, Sarikaya, Remzi, additional, Otar Yener, Gülcin, additional, Ozen, Seval, additional, Gul, Doruk, additional, Arslan, Gazi, additional, Kara, Soner Sertan, additional, Demirkol, Demet, additional, Yazici Ozkaya, Pinar, additional, Yozgat, Yilmaz, additional, Varan, Celal, additional, Kara, Manolya, additional, Arga, Gul, additional, Yakut, Nurhayat, additional, Kilic, Ahmet Osman, additional, Cakici, Ozlem, additional, Kucuk, Mehmet, additional, Kaba, Ozge, additional, Karaoglu Asrak, Hatice, additional, Bursal Duramaz, Burcu, additional, Dalkiran, Tahir, additional, Berna Anil, Ayse, additional, Turgut, Mehmet, additional, Karapinar, Bulent, additional, Somer, Ayper, additional, Elmali, Ferhan, additional, Dinleyici, Ener Cagri, additional, Ciftci, Ergin, additional, and Kara, Ates, additional
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- 2022
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44. Fatty Acid Composition of the Leaves of Some Salvia Taxa from Turkey
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Bakoglu, Adil, Kilic, Omer, and Kokten, Kagan
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- 2016
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45. Immune Response towards COVID-19
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Akram, Muhammad, primary, Ahmed, Waqas, additional, Jafari-Sales, Abolfazl, additional, Kusculu, Nilgun, additional, Bekhit, Mounir M, additional, Ramakrishnan, Prakash, additional, Seydou Mbaye, El Hadji, additional, Khan, Fahad Said, additional, Kilic, Omer, additional, Amjad Chishti, Muhammad, additional, Sharif, Aamir, additional, Solowski, Gawel, additional, Muddasar Saeed, Muhammad, additional, Elkhateeb, Waill, additional, and Daba, Ghoson, additional
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- 2021
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46. 261. A Rare Case of Meningitis and Symptomatic Hydrocephalus by Listeria Monocytogenes in Dermatomyositis: A Case Report
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Kiral, Eylem, primary, kacmaz, Ebru, additional, Bozan, Gurkan, additional, Arslanoglu, Ozgur, additional, Kilic, Omer, additional, and Dinleyici, Ener Cagri, additional
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- 2021
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47. Microscopic (LM and SEM) visualization of pollen ultrastructure among honeybee flora from lower Margalla Hills and allied areas.
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Zafar, Aqeela, Zafar, Muhammad, Ahmad, Mushtaq, Khan, Amir Muhammad, Mahmood, Tariq, Kilic, Omer, Fatima, Anam, Habib, Darima, Sultana, Shazia, Majeed, Salman, Attique, Rafia, and Nabila
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Microscopic visualization of micro‐morphological characters were analyzed using a scanning electron microscopic (SEM) tool, which has proven to be very successful to analyze the pollen surface peculiarities. The significant goal of this research was to perform microscopic examination of pollen of some of the most frequently visited honeybee floral species around apiaries. Micro‐morphological characterization of frequented honeybees foraged plants were discussed. A total of 15 species, belonging to 11 different families were identified for the foraging activities of honeybees, namely, Lantana camara, Jatropha integerrima, Helianthus annuus, Tecoma stans, Lagerstroemia indica, Duranta erecta, Cosmos sulphureus, Hymenocollis littoralis, Moringa oleifera, Cestrum nocturnum, Parthenium hysterophorus, Volkameria inermis, Catharanthus roseus, Malvastrum coromandelianum, and Citharexylum spinosum. The microscopic slides were prepared using the acetolysis method, and the qualitative and quantitative features were measured and described using microscopic tools. The pollen type sculpture varies from psilate scabrate to echinate and colpi from tricolpate to tetracolpate. Quantitative parameters such as polar diameter, mesocolpium distance, equatorial dimensions, aperture size, spine diameter, and exine thickness were calculated using IBM SPSS Statistics 20. The exine thickness was measured at its maximum in C. roseus (3.85 μm), whereas it was at its minimum of 0.90 μm in L. indica and D. erecta. Pollen fertility was estimated to be highest in H. annus (88%). The current research validates scanning microscopic features of pollen of the honeybee floral species, which is helpful for the accurate identification and commercializing of honey production to generate revenue for beekeepers through the exploration of bee floral diversity. Research Highlights: Pollen spectrum examination using microscopic imaging techniques.Variations examined through scanning microscopy in pollen ultrastructure.Micro‐morphology has taxonomic value for accurate identification of honeybee flora.Authentication of Honeybee floral species for sustainable beekeeping. [ABSTRACT FROM AUTHOR]
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- 2022
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48. Nasopharyngeal Meningococcal Carriage among Children and Adolescents in Turkey in 2018: An Unexpected High Serogroup X Carriage
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Kizil, Mahmut Can, primary, Kilic, Omer, additional, Ceyhan, Mehmet, additional, Iseri Nepesov, Merve, additional, Karbuz, Adem, additional, Kurugol, Zafer, additional, Hacimustafaoglu, Mustafa, additional, Celebi, Solmaz, additional, Dinleyici, Meltem, additional, Carman, Kursat Bora, additional, Bayhan, Cihangul, additional, Balliel, Yasemin, additional, Sutcu, Murat, additional, Kuyucu, Necdet, additional, Kondolot, Meda, additional, Kara, Soner Sertan, additional, Ocal Demir, Sevliya, additional, Cay, Ummuhan, additional, Gayretli Aydin, Zeynep Gokce, additional, Kaya, Mucahit, additional, and Dinleyici, Ener Cagri, additional
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- 2021
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49. Chapter 15 - Sesame (Sesamum indicum L.)
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Yaseen, Ghulam, Ahmad, Mushtaq, Zafar, Muhammad, Akram, Abida, Sultana, Shazia, Ahmed, Sidra Nisar, and Kilic, Omer
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- 2021
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50. Chapter 11 - Green solvents for qualitative pharmaceutical analysis
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Yaseen, Ghulam, Ahmad, Mushtaq, Akram, Abida, Zafar, Muhammad, Sultana, Shazia, Kilic, Omer, and Hussain, Amir
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- 2021
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