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288 results on '"Kikuta, T."'

6. A new HTS cable project in Japan

Author

Masuda, T., Yumura, H., Ohya, M., Kikuta, T., Hirose, M., Honjo, S., Mimura, T., Kito, Y., Yamamoto, K., Ikeuchi, M., and Ohno, R.

Subjects
Japan. Ministry of Economy, Trade and Industry -- Management, Alternating current -- Measurement, Electrical cables -- Design and construction, High temperature superconductors -- Research, Company business management, Business, Electronics, Electronics and electrical industries, New Energy and Industrial Technology Development Organization -- Management
Published
2009

12. Residual Donor Impurities in Undoped LEC SI-GaAs Crystals

Author

Kuramoto, K., Nakajima, M., Kikuta, T., Orito, F., Emori, H., Ishida, K., Goldanskii, Vitalii I., editor, Gomer, Robert, editor, Schäfer, Fritz Peter, editor, Toennies, J. Peter, editor, Benninghoven, A., editor, Okano, J., editor, Shimizu, R., editor, and Werner, H. W., editor

Published
1984
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16. Experimental study on evaluation of self-healing capability of FRCCs comprising different components

Author

Nishiwaki, T. (author), Yamada, M. (author), Kikuta, T. (author), Kwon, S. (author), Mihashi, H. (author), Nishiwaki, T. (author), Yamada, M. (author), Kikuta, T. (author), Kwon, S. (author), and Mihashi, H. (author)

Abstract

Fiber reinforced cementitious composite (FRCC) has a great capability for selfhealing of cracks. Concrete cracks with a sufficiently small crack width (below 0.1 mm) can be closed and self-healed by crystallization of calcium carbonate in the presence of moisture, even in the case of ordinary concrete. Such precipitation is caused by reaction of calcium ions and dissolved carbon dioxide. FRCC can accelerate the self-healing process mainly due to two characteristics, i.e., crack widths can be restricted to be narrow, and fibers bridging cracks can act as a core for precipitating chemical products. Previous research by the authors showed that some types of reinforcing fibers with polar groups, such as polyvinyl alcohol (PVA) with a hydroxy group, can induce a greater precipitation volume for calcium carbonate crystals around themselves than fibers without polarity, such as polypropylene (PP). In this study, a fundamental experiment was performed in order to specify the FRCC component materials that can enhance the self-healing effect. FRCCs with different types of reinforcing fibers (PVA and PP), aggregates, and admixtures (silica sand, limestone sand, and limestone powder) were subjected to the precipitation test—the volume of the precipitated calcium carbonate crystals around each fiber and on the crack surface of FRCC specimens was measured in order to estimate the selfhealing capability. Specimens with a crack surface were immersed for 7 days in a small water tank. The results showed that limestone sand and powder did not strongly affect the quantity of crystal precipitation around the exposed fiber; however, they enhanced the crystal precipitation area on the crack surface (flank). A large amount of precipitated crystal on the crack surface might enhance the self-healing function of FRCCs.

Published
2013

24. The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis.

Author

Ohara-Imaizumi, M., Cardozo, Alessandra K, Kikuta, T., Eizirik, Decio L., Nagamatsu, S., Ohara-Imaizumi, M., Cardozo, Alessandra K, Kikuta, T., Eizirik, Decio L., and Nagamatsu, S.

Abstract

The prediabetic period in type I diabetes mellitus is characterized by the loss of first phase insulin release. This might be due to islet infiltration mediated by mononuclear cells and local release of cytokines, but the mechanisms involved are unknown. To determine the role of cytokines in insulin exocytosis, we have presently utilized total internal reflection fluorescence microscopy (TIRFM) to image and analyze the dynamic motion of single insulin secretory granules near the plasma membrane in live beta-cells exposed for 24 h to interleukin (IL)-1beta or interferon (IFN)-gamma. Immunohistochemistry observed via TIRFM showed that the number of docked insulin granules was decreased by 60% in beta-cells treated with IL-1beta, while it was not affected by exposure to IFN-gamma. This effect of IL-1beta was paralleled by a 50% reduction in the mRNA and the number of clusters of SNAP-25 in the plasma membrane. TIRF images of single insulin granule motion during a 15-min stimulation by 22 mm glucose in IL-1beta-treated beta-cells showed a marked reduction in the fusion events from previously docked granules during the first phase insulin release. Fusion from newcomers, however, was well preserved during the second phase of insulin release of IL-1beta-treated beta-cells. The present observations indicate that IL-1beta, but not IFN-gamma, has a preferential inhibitory effect on the first phase of glucose-induced insulin release, mostly via an action on previously docked granules. This suggests that beta-cell exposure to immune mediators during the course of insulitis might be responsible for the loss of first phase insulin release., Journal Article, Research Support, Non-U.S. Gov't, info:eu-repo/semantics/published

Published
2004

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