1. Marked hypochloremic metabolic alkalosis with severe compensatory hypoventilation
- Author
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Edward F. Crocker, Kieran J. Key, Carl J. Lavie, and Thoms G. Ferguson
- Subjects
Male ,Hypochloremia ,Metabolic alkalosis ,Stomach Diseases ,Hypercapnia ,medicine ,Humans ,Pylorus ,business.industry ,Gastric outlet obstruction ,Alkalosis ,General Medicine ,Hypoventilation ,Middle Aged ,medicine.disease ,Pathophysiology ,Respiratory acidosis ,medicine.anatomical_structure ,Anesthesia ,Duodenal Ulcer ,medicine.symptom ,Chlorine ,business - Abstract
In metabolic alkalosis, a compensatory decrease in alveolar ventilation with hypercapnia has been noted only rarely. We recently managed a patient with gastric outlet obstruction from a duodenal ulcer who survived after arriving in the emergency room comatose with severe hypochloremic metabolic alkalosis, compensatory hypoventilation, and hypercapnia. We know of no report in the English literature of a patient with gastric outlet obstruction having a respiratory acidosis or hypochloremia as severe as that in our patient. Proper understanding of the pathophysiology of primary metabolic alkalosis due to gastric losses is necessary to correct the acid-base abnormalities quickly and to restore normal alveolar ventilation.
- Published
- 1986