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24 results on '"Kido, Tomoko"'

6. Postprandial hypotension as a risk marker for asymptomatic lacunar infarction.

Author

00268749, Tabara, Yasuharu, Okada, Yoko, Uetani, Eri, Nagai, Tokihisa, Igase, Michiya, Kido, Tomoko, Ochi, Namiko, Ohara, Maya, Takita, Rie, Kohara, Katsuhiko, Miki, Tetsuro, 00268749, Tabara, Yasuharu, Okada, Yoko, Uetani, Eri, Nagai, Tokihisa, Igase, Michiya, Kido, Tomoko, Ochi, Namiko, Ohara, Maya, Takita, Rie, Kohara, Katsuhiko, and Miki, Tetsuro

Abstract

[Objective]: Increasing blood pressure (BP) variability is reported to be a cardiovascular risk factor. However, the clinical implications of postprandial hypotension (PHYPO), a commonly observed BP variability in elderly persons, are poorly understood. Here, we investigated the possible associations between postprandial BP decline and asymptomatic cerebral damage in community residents. [Methods]: Study participants consisted of 1308 general community residents (65 ± 9 years old). Postprandial BP change was calculated from SBP measured just before and 30 min after lunch. PHYPO was defined as a decline in SBP of more than 20 mmHg. The presence of asymptomatic cerebrovascular damage was evaluated by brain MRI. [Results]: Prevalence of lacunar infarction was significantly higher in participants with PHYPO (P = 0.004). A postprandial decline in SBP was linearly increased with the number of lacunar lesions (none, n = 1200, −3.4± 11.3 mmHg; one lesion, n = 82, −5.2 ± 11.8; two lesions, n = 18, −6.9 ± 11.5; three lesions, n = 7, −13.4 ± 11.3; and four lesions, n = 1, −27; P = 0.012). Although participants with PHYPO were older (P < 0.001) and had higher preprandial BP (P < 0.001) and faster pulse wave velocity (P = 0.001), multivariate analysis adjusted for these covariates indicated that postprandial BP decline was an independent determinant for the number of lacunar infarctions (P = 0.004). No significant associations were observed with grade of periventricular hyperintensity or frequency of microbleeds. These relationships were also found in an analysis based on central BP, whereas no superiority was seen in the analysis based on central BP. [Conclusion]: Postprandial BP decline is an overlooked risk marker for asymptomatic lacunar infarction in community residents.

Published
2014

8. Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: The J-SHIP and Toon Health Study.

Author

00268749, Tabara, Yasuharu, Igase, Michiya, Saito, Isao, Nishida, Wataru, Kohara, Katsuhiko, Sakurai, Susumu, Kawamura, Ryoichi, Okada, Yoko, Hitsumoto, Shinichi, Onuma, Hiroshi, Nagai, Tokihisa, Takata, Yasunori, Uetani, Eri, Takita, Rie, Kido, Tomoko, Ochi, Namiko, Osawa, Haruhiko, Tanigawa, Takeshi, Miki, Tetsuro, 00268749, Tabara, Yasuharu, Igase, Michiya, Saito, Isao, Nishida, Wataru, Kohara, Katsuhiko, Sakurai, Susumu, Kawamura, Ryoichi, Okada, Yoko, Hitsumoto, Shinichi, Onuma, Hiroshi, Nagai, Tokihisa, Takata, Yasunori, Uetani, Eri, Takita, Rie, Kido, Tomoko, Ochi, Namiko, Osawa, Haruhiko, Tanigawa, Takeshi, and Miki, Tetsuro

Published
2013

9. Postprandial hypertension, an overlooked risk marker for arteriosclerosis.

Author

00268749, Uetani, Eri, Tabara, Yasuharu, Igase, Michiya, Guo, Haiyan, Kido, Tomoko, Ochi, Namiko, Takita, Rie, Kohara, Katsuhiko, Miki, Tetsuro, 00268749, Uetani, Eri, Tabara, Yasuharu, Igase, Michiya, Guo, Haiyan, Kido, Tomoko, Ochi, Namiko, Takita, Rie, Kohara, Katsuhiko, and Miki, Tetsuro

Published
2012

10. Association of hematological parameters with insulin resistance, insulin sensitivity, and asymptomatic cerebrovascular damage: The J-SHIP and Toon Health Study

Author

Tabara, Yasuharu, primary, Igase, Michiya, additional, Saito, Isao, additional, Nishida, Wataru, additional, Kohara, Katsuhiko, additional, Sakurai, Susumu, additional, Kawamura, Ryoichi, additional, Okada, Yoko, additional, Hitsumoto, Shinichi, additional, Onuma, Hiroshi, additional, Nagai, Tokihisa, additional, Takata, Yasunori, additional, Uetani, Eri, additional, Takita, Rie, additional, Kido, Tomoko, additional, Ochi, Namiko, additional, Osawa, Haruhiko, additional, Tanigawa, Takeshi, additional, and Miki, Tetsuro, additional

Published
2013
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21. Association of Central Systolic Blood Pressure With Intracerebral Small Vessel Disease in Japanese.

Author

Ochi, Namiko, Kohara, Katsuhiko, Tabara, Yasuharu, Nagai, Tokihisa, Kido, Tomoko, Uetani, Eri, Ochi, Masayuki, Igase, Michiya, and Miki, Tetsuro

Subjects
ARTERIAL diseases, BLOOD pressure, HYPERTENSION, CAROTID artery, HEMODYNAMICS, MAGNETIC resonance imaging, JAPANESE people, DISEASES
Abstract

BackgroundRecent studies have reported the association between advanced arterial stiffness and brain small vessel diseases (SVDs). Two possible hemodynamic mechanisms, increases in central blood pressure (BP) and pulsatile flow load to the brain, have been speculated to link arterial stiffness and SVD. The carotid flow augmentation index (AI) has been proposed as an index of pulsatile flow to the brain. We compared its association with brain SVD with that of central BP in a general population.MethodsSubjects were 500 individuals free from symptomatic cardiovascular diseases with a mean age of 66.9 ± 8.4 years. Brachial-ankle pulse wave velocity (baPWV) was measured as an index of arterial stiffness. Carotid flow AI was obtained by Doppler ultrasonography. The presence of silent cerebral lacunar infarcts (SCI) was determined as a manifestation of SVD by 3-tesla magnetic resonance imaging (MRI). Second peak radial systolic BP (SBP2) and pulse pressure (PP2) were used as estimates of central BP.ResultsbaPWV was significantly associated with radial BP2 (r = 0.55, P < 0.0001) but not with carotid flow AI (r = 0.03, P = 0.51). Radial BPs and baPWV, but not flow AI, were significantly higher in subjects with SCI. Radial SBP2 had higher odds ratio for the presence of SCI than brachial SBP, PP, and radial PP2. Logistic regression analysis showed that radial SBP2, but not flow AI, was independently related to the presence of SCI.ConclusionThese findings indicate that the SBP2, an estimate of central SBP, is significantly associated with the presence of SVD in an apparently healthy general population.American Journal of Hypertension 2010; doi:10.1038/ajh.2010.60 [ABSTRACT FROM AUTHOR]

Published
2010
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24. [Right oculomotor nerve palsy due to juvenile neurosyphilis].

Author

Yamasaki R, Kido T, and Yamashita Y

Subjects
Acute Disease, Adult, Diagnosis, Differential, Female, Humans, Infusions, Intravenous, Neurosyphilis diagnosis, Neurosyphilis drug therapy, Oculomotor Nerve Diseases diagnosis, Oculomotor Nerve Diseases drug therapy, Pulse Therapy, Drug, Treatment Outcome, Neurosyphilis complications, Oculomotor Nerve Diseases etiology, Penicillin G administration & dosage
Published
2004

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