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18 results on '"Khusnutdinova, Elsa"'

4. Novel MicroRNA Binding Site SNPs and the Risk of Clear Cell Renal Cell Carcinoma (ccRCC): A Case-Control Study

Author

Gilyazova, Irina R., primary, Beeraka, Narasimha M., additional, Klimentova, Elizaveta A., additional, Bulygin, Kirill V., additional, Nikolenko, Vladimir N., additional, Izmailov, Adel A., additional, Gilyazova, Gulshat R., additional, Pavlov, Valentin N., additional, Khusnutdinova, Elsa K., additional, Somasundaram, Siva G., additional, Kirkland, Cecil E., additional, and Aliev, Gjumrakch, additional

Published
2021
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5. Mitochondrial variation of modern Tuscans supports the near eastern origin of Etruscans

Author

Achilli, Alessandro, Olivieri, Anna, Pala, Maria, Metspalu, Ene, Fornarino, Simona, Battaglia, Vincenza, Accetturo, Matteo, Kutuev, Ildus, Khusnutdinova, Elsa, Pennarun, Erwan, Cerutti, Nicoletta, Di Gaetano, Cornelia, Crobu, Francesca, Palli, Domenico, Matullo, Giuseppe, Santachiara-Benerecetti, A. Silvana, Cavalli-Sforza, L. Luca, Semino, Ornella, Villems, Richard, Hans-Jurgen, Bandelt, Piazza, Alberto, and Torroni, Antonio

Subjects
Etruscans -- Genetic aspects, Mitochondrial DNA -- Research, Genetic variation -- Research, Biological sciences
Abstract

The mitochondrial DNA (mtDNA) of 322 subjects from three well-defined areas of Tuscany was analyzed. The aim is to explain the origin of the Etruscan people, their language and sophisticated culture, including an Aegean/Anatolian origin.

Published
2007

6. Phylogeography of Y-chromosome haplogroup I reveals distinct domains of prehistoric gene flow in Europe

Author

Rootsi, Siiri, Magri, Chiara, Kivisild, Toomas, Benuzzi, Georgia, Help, Hela, Bermisheva, Marina, Kutuev, Ildus, Barac, Lovorka, Pericic, Marijana, Balanovsky, Oleg, Pshenichnov, Andrey, Dion, Daniel, Grobei, Monica, Zhivotovsky, Lev A., Battaglia, Vincenza, Achilli, Alessandro, Zahery, Nadia Al-, Parik, Juri, King, Roy, Cinnioglu, Cengiz, Khusnutdinova, Elsa, Rudan, Pavao, Balanovska, Elena, Scheffrahn, Wolfgang, Simonescu, Maya, Brehm, Antonio, Goncalves, Rita, Rosa, Alexandra, Moisan, Jean-Paul, Chaventre, Andre, Ferak, Vladimir, Furedi, Sandor, Oefner, Peter J., Shen, Peidong, Beckman, Lars, Mikerezi, Ilia, Terzic, Rifet, Primorac, Dragan, Cambon-Thomsen, Anne, Krumina, Astrida, Torroni, Antonio, Underhill, Peter A., Santachiara-Benerecetti, A. Silvana, Villems, Richard, and Semino, Ornella

Subjects
Human genetics -- Research, Biological sciences
Published
2004

7. Origin and diffusion of mtDNA haplogroup X

Author

Reidla, Maere, Kivisild, Toomas, Metspalu, Ene, Kaldma, Katrin, Tambets, Kristiina, Tolk, Helle-Viivi, Parik, Juri, Loogvali, Eva-Liis, Derenko, Miroslava, Malyarchuk, Boris, Bermisheva, Marina, Zhadonov, Sergey, Pennarun, Erwan, Gubina, Marina, Golubenko, Maria, Damba, Larisa, Fedorova, Sardana, Gusar, Vladislava, Grechanina, Elena, Mikerezi, Ilia, Moisan, Jean-Paul, Chaventre, Andre, Khusnutdinova, Elsa, Osipova, Ludmila, Stepanov, Vadim, Voevoda, Mikhail, Achilli, Alessandro, Rengo, Chiara, Rickards, Olga, De Stefano, Gian Franco, Papiha, Surinder, Beckman, Lars, Janicijevic, Branka, Rudan, Pavao, Anagnou, Nicholas, Michalodimitrakis, Emmanuel, Koziel, Slawomir, Usanga, Esien, Geberhiwot, Tarekegn, Herrnstadt, Corinna, Howell, Neil, Torroni, Antonio, and Villems, Richard

Subjects
DNA -- Research, Biological sciences
Published
2003

9. Disuniting Uniformity: A Pied Cladistic Canvas of mtDNA Haplogroup H in Eurasia

Author

Loogväli, Eva-Liis, Roostalu, Urmas, Malyarchuk, Boris A., Derenko, Miroslava V., Kivisild, Toomas, Metspalu, Ene, Tambets, Kristiina, Reidla, Maere, Tolk, Helle-Viivi, Parik, Jüri, Pennarun, Erwan, Laos, Sirle, Lunkina, Arina, Golubenko, Maria, Barać, Lovorka, Peričić, Marijana, Balanovsky, Oleg P., Gusar, Vladislava, Khusnutdinova, Elsa K., Stepanov, Vadim, Puzyrev, Valery, Rudan, Pavao, Balanovska, Elena V., Grechanina, Elena, Richard, Christelle, Moisan, Jean-Paul, Chaventré, André, Anagnou, Nicholas P., Pappa, Kalliopi I., Michalodimitrakis, Emmanuel N., Claustres, Mireille, Gölge, Mukaddes, Mikerezi, Ilia, Usanga, Esien, and Villems, Richard

Published
2004

12. Genetic relations in Eastern Europe populations

Author

Yankovsky, Nick, Orekhov, Vladimir, Tolk, Helle-Viivi, Injutin, Alex, Laos, Sirle, Kojekbaeva, Janna, Metspalu, Ene, Reidla, Maere, Parik, Juri, Rootsi, Siiri, Adojaan, Maarja, Kivisild, Toomas, Barać, Lovorka, Rudan, Pavao, Koziel, Slavomir, Ferak, Vladimir, Ivanov, Pavel, Khusnutdinova, Elsa, Villems, Richard, Brown, Michael, Cavalli-Sforza, Luca L., and Chakravarti, Aravinda

Subjects
mtDNA, Y chromosome, Eastern Europe populations, population genetics, anthropology, geographic locations, humanities
Abstract

Analysis of mtDNA (HSV-I sequencing and typing of haplogroup specific RFLPs) and Y chromosome markers (seven biallelic markers and six STRs) was performed in five Slavic populations: Russians, Poles, Czechs, Slovaks and Croatians. Some neighboring Finno-Ugric and Altaic populations were also studied for comparisons: Estonians, Hungarians, Udmurts, Maris, Chuvashis, Tatars and Turks. In total, these data of more than 1500 individuals were compared to data available about western European populations. Analyses of both mtDNA and Y chromosome of Slavs revealed significant admixture with populations neighboring them geographically. The frequency distributions observed in Europe of haplogroup U3, U4, U5, M J1 in mtDNA and haplogroups 3 and 16 in Y chromosome also pass through territories inhabited by Slavs. The Western European populations such as Germans, Austrians, Swiss. The populations located to east instance, high percentage of C allele in Tat locus of the Y chromosome in Ugric substratum of the territory populated by Russians. The Croatians also show more proximity with their non-Slavic neighbours. We conclude that in most cases the haplogroup frequencies in Slavs correlate more with geographic location of population than with its linguistic affiliation.

Published
2000

14. Polymorphism C/T-13910 of the LCT gene regulatory region and lactase deficiency in Eurasian populations

Author

Sokolova, Maria V, primary, Vasilyev, Eugene V, additional, Kozlov, Andrey I, additional, Rebrikov, Denis V, additional, Senkeeva, Svetlana S, additional, Kozhekbaeva, Zhanna M, additional, Lundup, Aleksey V, additional, Svechnikova, Natalia S, additional, Ogurtsov, Pavel P, additional, Khusnutdinova, Elsa K, additional, Yankovsky, Nikolay K, additional, and Borinskaya, Svetlana A, additional

Published
2007
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15. Beringian Standstill and Spread of Native American Founders

Author

Tamm, Erika, primary, Kivisild, Toomas, additional, Reidla, Maere, additional, Metspalu, Mait, additional, Smith, David Glenn, additional, Mulligan, Connie J., additional, Bravi, Claudio M., additional, Rickards, Olga, additional, Martinez-Labarga, Cristina, additional, Khusnutdinova, Elsa K., additional, Fedorova, Sardana A., additional, Golubenko, Maria V., additional, Stepanov, Vadim A., additional, Gubina, Marina A., additional, Zhadanov, Sergey I., additional, Ossipova, Ludmila P., additional, Damba, Larisa, additional, Voevoda, Mikhail I., additional, Dipierri, Jose E., additional, Villems, Richard, additional, and Malhi, Ripan S., additional

Published
2007
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16. Mitochondrial DNA Variation of Modern Tuscans Supports the Near Eastern Origin of Etruscans

Author

Achilli, Alessandro, primary, Olivieri, Anna, additional, Pala, Maria, additional, Metspalu, Ene, additional, Fornarino, Simona, additional, Battaglia, Vincenza, additional, Accetturo, Matteo, additional, Kutuev, Ildus, additional, Khusnutdinova, Elsa, additional, Pennarun, Erwan, additional, Cerutti, Nicoletta, additional, Di Gaetano, Cornelia, additional, Crobu, Francesca, additional, Palli, Domenico, additional, Matullo, Giuseppe, additional, Santachiara-Benerecetti, A. Silvana, additional, Cavalli-Sforza, L. Luca, additional, Semino, Ornella, additional, Villems, Richard, additional, Bandelt, Hans-Jürgen, additional, Piazza, Alberto, additional, and Torroni, Antonio, additional

Published
2007
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18. Novel MicroRNA Binding Site SNPs and the Risk of Clear Cell Renal Cell Carcinoma (ccRCC): A Case-Control Study.

Author

Gilyazova IR, Beeraka NM, Klimentova EA, Bulygin KV, Nikolenko VN, Izmailov AA, Gilyazova GR, Pavlov VN, Khusnutdinova EK, Somasundaram SG, Kirkland CE, and Aliev G

Abstract

Background: Renal cell carcinoma represents 3% of all adult malignancies. MicroRNAs exhibit specific functions in various biological processes through their interaction with cellular mRNA involved in apoptosis and cell cycle control. Recent studies have reported the potential association of single-nucleotide polymorphisms (SNPs) in miRNA-binding sites of VHL-HIF1α pathway genes with renal cancer development and progression., Objective: The objective of this study is to investigate SNPs invoking an alteration in the nature of interaction with miRNA binding sites of VHL-HIF1α pathway genes., Patients & Methods: Total 450 cases of histologically and clinically verified ccRCC and 490 controls were included in our study. Genotyping was performed using a TaqMan PCR allelic discrimination method. Kaplan-Meier method of statistical analysis was implemented to analyze the overall patient survival rate., Results: Polymorphism rs10491534 in TSC1 gene was significantly associated with risk of developing advanced ccRCC. Allele G of rs1642742 in VHL gene was significantly prevalent in ccRCC compared with control group aged 55 and older (OR = 1.5566; CI [1.1532-2.1019]). Results from the dominant model combining individuals with AG or AA genotype showed that the A allele bearers of CDCP1 rs6773576 exhibited higher risk of death compared to GG carriers (HR 3.93, 95% CI 1.76-17.21, log-rank P = 0.0033)., Conclusion: The present study delineated the association of miRNA binding site variants in VHL-HIF1α pathway genes with the ccRCC risk, which may affect clinical outcome., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)

Published
2020
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