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3 results on '"Khudiakova OV"'

1. [Features of DNA synthesis in chromatin from rat blood lymphocytes upon exposure to varying doses of ionizing radiation].

Author

Vynohradova RP, Khudiakova OV, Kysel'ova IK, Uvarova OV, Imedadze SP, and Tron' KV

Subjects
Animals, Dose-Response Relationship, Radiation, Lymphocytes metabolism, Male, Rats, Rats, Wistar, Chromatin metabolism, DNA Replication, Lymphocytes radiation effects
Abstract

Changes in the level of chromatin DNA synthesis after the total X-ray irradiation of rats in the dozes 0.5 Gr, 1 Gr and 7.76 Gr were shown. Interrelations between postradiation correlation of protein and DNA in lymphocytes of peripheral of blood rats were analyzed.

Published
1999

2. [Regulatory components of the eukaryotic translation apparatus in normal states and after exposure to ionizing radiation].

Author

Vynohradova RP, Zudina OF, Khudiakova OV, and Imedadze SP

Subjects
Amino Acyl-tRNA Synthetases metabolism, Animals, Cyclic AMP metabolism, Cyclic GMP metabolism, Dinoprost metabolism, Dinoprostone metabolism, Liver enzymology, Liver metabolism, Liver radiation effects, Rats, X-Rays, Protein Biosynthesis radiation effects
Abstract

The comparative analysis of content prostaglandins E2, F2 alpha and cAMP, cGMP in the compositions of the high-molecular aminoacyl-tRNA synthetase complexes and endoplasmic reticulum vesicules from the rat liver has been carried out. The influence of lethal and sublethal X-ray doses on the levels of cyclic nucleotides and prostaglandins has been studied. Cyclic nucleotides and prostaglandins proved to be rapid and high sensitive transmitters of ionizing radiation influence on the eukaryotic translation apparatus.

Published
1998

3. [Effect of ionizing radiation on the chromatin fraction components in rat blood lymphocytes].

Author

Khudiakova OV, Vinogradova RP, Babenko OIu, Korneva SV, Gabeliuk AV, Uvarova OV, Salabaĭ PV, and Kucherenko MIe

Subjects
Animals, Cell Fractionation, Chromatin chemistry, Endodeoxyribonucleases radiation effects, Endopeptidases radiation effects, Lymphocytes chemistry, Rats, Rats, Wistar, Whole-Body Irradiation, Chromatin radiation effects, Lymphocytes radiation effects
Abstract

Changes in the level of blood lymphocyte chromatin degradation and relaxation were investigated after the whole body irradiation with doses up to 0.21 C/kg. It was shown that ionizing irradiation initiated the increase of nuclear endogenous Ca/mg-dependent endonuclease, and protease activities.

Published
1995

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