12 results on '"Khosla E"'
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2. A comparative study of salivary buffering capacity, flow rate, resting pH, and salivary Immunoglobulin A in children with rampant caries and caries-resistant children
- Author
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Sundaresan, C, primary, Mathai, V, additional, Khosla, E, additional, Gaffoor, FMA, additional, and Kuriakose, S, additional
- Published
- 2013
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3. Removal of basic dye from aqueous solution by biosorption on to sewage sludge
- Author
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Pragnesh Dave, Kaur, S., and Khosla, E.
4. Assessment of Acoustic and Nasalance Improvement in Maxillary Obturator Patients Using PRAAT Software: An In Vivo Study.
- Author
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Bhushan P, Thenumkal E, Khosla E, Bharath VUS, Varma RA, and Govindankutty RK
- Subjects
- Humans, Middle Aged, Male, Adult, Female, Aged, Software, Maxilla surgery, Voice Quality, Palatal Obturators, Speech Acoustics
- Abstract
Aim: The purpose of this study was to evaluate the improvement in acoustic and nasalance in patients with maxillary obturators, using PRAAT software., Materials and Methods: The current study comprised a total of 16 patients who had acquired maxillary defects. Regardless of gender, the age range of these patients was 40-75 years old. The total number of patients were randomly divided into two groups (8 participants in each group) namely (A) Interim obturator group and (B) Definitive obturator group. Analysis was done using PRAAT software for two speech parameters namely nasalance and acoustic value. The first stage of speech analysis was completed without the use of an obturator, whereas the second stage involved inserting the obturator on the same day. The third stage occurred 2 months after the usage of the obturator. The data were recorded and statistically analyzed., Results: In definitive obturator group, mean value for relative nasalance increases from before prosthesis (60.93 ± 3.34 db) to after 2 months of prosthesis (70.53 ± 2.24 db) while in interim group increased from 57.55 ± 4.31 db (before prosthesis) to 63.77 ± 3.66 db (after 2 months of prosthesis). This improvement was more marked with definitive obturator than interim obturator. The F2-F1 comparative mean value changed from before prosthesis to immediate after prosthesis in definitive group for /a/, /e/, and /u/ vowels was 9.77, 22, and 24.38, respectively. F2-F1 comparative mean changes from before prosthesis to after 2 months of prosthesis was 102, 75.75, and 87 for three vowels /a/, /e/, and /u/, respectively. Similarly, F2-F1 mean value in interim prosthesis group changes from before to after 2 months of prosthesis was 62.25, 27.62, and 1.75 for /a/, /e/, and /u/, respectively., Conclusion: On conclusion, the definitive obturators were well-tolerated by patients with major defects and the results show that maxillary resection significantly impairs speech and definitive obturator rehabilitation is effective in regaining nasalance and acoustic speech components., Clinical Significance: Speech disorders in maxillectomy patients are a significant clinical issue since the surgery results in hypernasality, which impairs a person's ability to understand their own speech. Either surgical techniques or prosthetic rehabilitation are used to correct these abnormalities. Certain people require prosthetics to fix their speech even after surgery. How to cite this article: Bhushan P, Thenumkal E, Khosla E, et al. Assessment of Acoustic and Nasalance Improvement in Maxillary Obturator Patients Using PRAAT Software: An In Vivo Study. J Contemp Dent Pract 2024;25(7):656-660.
- Published
- 2024
- Full Text
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5. Evaluation of Probiotic Effects of Lactobacilli on Mutans Streptococci: An In Vitro Study.
- Author
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Venugopal M, Khosla E, K KA, Alex V, T N, and Kumar H
- Subjects
- Humans, Lactobacillus, Vancomycin, Cephalothin, Agar, Streptococcus mutans, Lactobacillus acidophilus, Anti-Bacterial Agents pharmacology, Tetracycline, Penicillins, Erythromycin, Dental Caries microbiology, Probiotics pharmacology
- Abstract
Aim: The aim of the present study is to evaluate the probiotic effect of Lactobacillus acidophilus and Lactobacillus rhamnosus on clinical isolates of Mutans Streptococci (MS) and antibiotic susceptibility of these strains to commonly used antibiotics in dentistry., Materials and Methods: Plaque samples from permanent first molars were collected and transferred aseptically onto Mitis-Salivarius agar and incubated at 37°C for 24 hours in the presence of 5-10% CO
2 . Mutans streptococci colonies were identified biochemically using Hi-Strep identification kit. The inhibitory activity of the clinical strains of MS on Lactobacilli was investigated using agar-overlay interference technique. Positive inhibition was appreciated as a clear zone around the Lactobacilli . Disk diffusion assay was done as described by CLSI M100-S25 for antibiotic susceptibility. The zone of growth inhibition caused by Lactobacilli and antibiotics on MS clinical strains was measured directly using a vernier caliper. Statistical analysis was done using independent t -test., Results: Mutans streptococci exhibited positive inhibition with both the probiotic strains and L. acidophilus showed more zones of inhibition than L. rhamnosus . Antibiotic susceptibility of clinical strains of MS showed sensitivity to penicillin and vancomycin, however, tetracycline and erythromycin showed very few resistant strains. The highest zone of inhibition was shown by cephalothin followed by penicillin, tetracycline, ciprofloxacin, erythromycin, and vancomycin., Conclusion: L. rhamnosus and L. acidophilus have strong inhibitory effects on clinical strains of MS. Lactobacillus acidophilus showed a higher zone of inhibition. All the clinical strains of MS were sensitive to penicillin and vancomycin. The highest zone of inhibition was shown by cephalothin., Clinical Significance: Dental caries remains silent epidemic and increasing antibiotic resistance is another major challenge that threatens the world. Newer methods such as whole-bacteria replacement therapy using probiotics for decreasing harmful oral pathogens and reducing the intake of antibiotics must be explored. More researches to promote use of probiotics should be initiated due to its possible preventive and health maintenance benefits providing an end to new cavities and antibiotic resistance.- Published
- 2022
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6. Resolution without discontinuation: heart failure during clozapine treatment.
- Author
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Whiskey E, Yuen S, Khosla E, Piper S, O'Flynn D, and Taylor D
- Abstract
Clozapine is an atypical antipsychotic recommended for patients with treatment-resistant schizophrenia whose illness has not responded adequately to treatment despite the sequential use of at least two different antipsychotic drugs at therapeutic doses. Unfortunately, clozapine is frequently discontinued due to both real and perceived serious, and potentially life-threatening, adverse effects, contributing to the underutilisation of the most effective treatment in refractory psychotic disorders. Here, we present the case of a 51-year-old man with treatment-resistant schizoaffective disorder, who was admitted to a locked rehabilitation unit for a clozapine rechallenge. Within 6 months after the clozapine rechallenge, he was diagnosed with heart failure likely secondary to his antipsychotic treatment. Clozapine-induced heart failure usually prompts immediate cessation of treatment. However, in this case, clozapine was continued with cardiology consultation. Ramipril and bisoprolol were initiated and the patient's cardiac condition progressively improved over time. Clozapine-induced heart failure is a serious cardiovascular complication of treatment, usually resulting in discontinuation of treatment. Although there are cases of successful rechallenge, temporary cessation of treatment can lead to severe psychotic exacerbation and non-engagement with cardiac specialists. More evidence is required for continued use of clozapine in a patient with clozapine-induced cardiac complications., Competing Interests: Conflict of interest statement: The authors declare that there is no conflict of interest., (© The Author(s), 2020.)
- Published
- 2020
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7. Effects of different dentinal drying methods on the adhesion of glass ionomer restorations to primary teeth.
- Author
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Jose SC, Khosla E, Abraham KK, James AR, and Thenumkal E
- Subjects
- Acrylic Resins, Child, Dentin, Glass Ionomer Cements, Humans, Materials Testing, Silicon Dioxide, Tooth, Deciduous, Dental Bonding
- Abstract
Background: Glass ionomer cements that form an inevitable part of pediatric restorative dentistry are inherently sensitive to moisture. The influence of different drying techniques on the shear bond strength of glass ionomer cements to primary teeth dentin has not been established., Aims: The purpose of the study was to evaluate the effects of different drying methods for different drying time periods on the shear bond strength of GC Fuji IX to primary tooth dentine., Subjects and Methods: A total of 135 caries-free primary teeth were selected and ground to a flat dentinal surface. Specimens were randomly divided into three groups - air dry, blot dry, and suction dry of 45 specimens each. Of these, 15 specimens each were dried for 2 s, 5 s, and 10 s. GC Fuji IX was condensed into Teflon molds, and the specimens were subjected to shear bond strength testing., Results: The mean shear bond strength values for the different time intervals were analyzed with analysis of variance test. In the air-dry group, the maximum shear bond strength values were obtained when the specimens were dried for 5 s and the least when dried for 2 s (P = 0.00). In the blot-dry and suction-dry groups, the highest values were obtained when the specimens were dried for 10 s and least for 2 s (P = 0.039 and 0.000, respectively)., Conclusions: Among the three drying methods employed in the study, the maximum shear bond strength of the glass ionomer restoration was observed in the air-dry group., Competing Interests: None
- Published
- 2019
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8. Blandin and Nuhn mucocele in a pediatric patient.
- Author
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Jose SC, Abraham KK, and Khosla E
- Subjects
- Biopsy, Child, Female, Humans, Incisor surgery, Tooth Extraction, Tooth, Deciduous surgery, Mucocele pathology, Mucocele surgery, Tongue Diseases pathology, Tongue Diseases surgery
- Abstract
Oral mucoceles are benign lesions that may appear in any location on the mucosal surfaces of the oral cavity where underlying minor salivary glands are found. The lower lip is the most frequently affected and the most widely reported location. Mucoceles involving the glands of Blandin and Nuhn are infrequent and constitute only about 1.9%-10.3% of the reported cases. Superficial mucoceles are a rare subtype of the Blandin and Nuhn mucoceles and are found only in 4.3%-10% of the mucocele excisions. The purpose of this report is to present a case of a superficial mucocele in the ventral surface of the tongue in a 7-year-old child. The lesion was treated with excisional biopsy., Competing Interests: There are no conflicts of interest
- Published
- 2018
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9. Surface micromorphological changes of glass ionomer following application of 1.23% acidulated phosphate fluoride: a scanning electron microscope study.
- Author
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Khosla E, Kuriakose S, and Suderasen C
- Subjects
- Microscopy, Electron, Scanning, Surface Properties, Acidulated Phosphate Fluoride chemistry, Glass Ionomer Cements
- Abstract
Objectives: The purpose of this study was to evaluate the surface micromorphological changes of conventional glass ionomer cement (GIC) (Fuji II, GC Corporation, Tokyo, Japan) and high strength, high viscosity GIC (Fuji IX GP, GC Corporation) subjected to 1.23% acidulated phosphate fluoride (APF) gel for 4 min. It also evaluated the surface micromorphological changes that occurred in these materials when they were coated with a layer of glass ionomer varnish prior to the application of 1.23% APF gel., Materials and Methods: A total of 60 uniform glass ionomer cylinders were prepared (30 of each Fuji II and Fuji IX) and stored in distilled water for 48 h, following which they were divided into six groups depending on the surface treatment. Group 1: Fuji II alone, Group 2: Fuji IX alone, Group 3: Fuji II + 1.23% APF gel for 4 min, Group 4: Fuji IX + 1.23% APF gel for 4 min, Group 5: Fuji II + varnish + 1.23% APF gel for 4 min, and Group 6: Fuji IX + varnish + 1.23% APF gel for 4 min. After the required surface treatment had been done, the specimens were mounted, coated, and evaluated under scanning electron microscope., Statistical Analysis: Kruskal-Wallis test applied to compare the level of degradation among the groups subjected to treatment was highly significant (P < 0.001). Mann-Whitney test was applied to test the association between glass ionomer varnish and level of surface degradation and was also statistically significant (P = 0.001)., Results: The results indicated that APF gel etched the surface of both Fuji II and Fuji IX. However, Fuji IX showed to possess better resistance to the erosive effect of APF than Fuji II. It was also observed that application of glass ionomer varnish prior to APF gel application protected the glass ionomer from the erosive effect of APF gel., Conclusion: APF gel caused erosive wear of the GICs esp. Fuji II. Hence, it is advisable to avoid the use of APF containing preparations for regular home use especially in children having glass ionomer restoration. If APF gel is indicated or preferred for professional application, it is recommended to apply glass ionomer varnish on the restored teeth prior to the APF gel application.
- Published
- 2014
- Full Text
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10. Desmoplastic fibroblastoma (collagenous fibroma) in the oral cavity.
- Author
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Varghese T, Pillai KS, Sarojini SB, and Khosla E
- Subjects
- Child, Humans, Male, Fibroma, Desmoplastic diagnosis, Mouth Neoplasms diagnosis
- Abstract
Desmoplastic fibroblastoma (DF) also known as collagenous fibroma (CF) is a rare benign soft tissue tumor that occurs in varied locations in the body. Very few cases of DF have been reported in the oral cavity. We report a case of DF in an 8-year-old boy presented as a slow-growing mass in the buccal mucosa since 6 months. Histopathology, special staining and immunohistochemistry studies suggested a diagnosis of CF. As per our knowledge of the current literature this is the seventh case reported in the oral cavity and the first report in a child.
- Published
- 2014
- Full Text
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11. Eruption of odontomas into the oral cavity: a report of 2 cases.
- Author
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Bhargavan Sarojini S, Khosla E, Varghese T, and Johnson Arakkal L
- Abstract
Odontomas are the commonest odontogenic tumors of the oral cavity and are by nature asymptomatic. They consist mainly of dental tissue that may or may not be arranged in an orderly fashion. Their presence is often detected accidentally or due to the presence of a dental disturbance such as an unerupted tooth. The very rarity of odontomas erupting into the oral cavity validates the need for more current literature on the phenomenon. Our report of two cases aims to present and discuss the rare event of an erupting odontoma with the dental community.
- Published
- 2014
- Full Text
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12. Salivary calculus: an insight into its pathogenesis--a case report of parotid sialolith in a 9 year old child.
- Author
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Khosla E, Kurian J, and Kuriakose S
- Subjects
- Child, Female, Humans, Parotid Diseases etiology, Salivary Duct Calculi etiology, Parotid Diseases pathology, Salivary Duct Calculi pathology
- Abstract
The occurrence of sialolithiasis in children is uncommon, while parotid sialoliths are rare. A case of parotid sialolith in a 9 year old child is reported.
- Published
- 1999
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