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Your search keyword '"Khorshidi, Mahsa"' showing total 9 results
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9 results on '"Khorshidi, Mahsa"'

3. RETRACTED: Spectroscopic and molecular modeling studies of binding interaction between the new complex of yttrium and 1,10-phenanthroline derivatives with DNA and BSA.

Author

Khorshidi, Mahsa, Asadpour, Saeid, Aramesh-Boroujeni, Zahra, Kooravand, Masoumeh, Dehkordi, Maryam Mobini, Gulcin, Ilhami, and Shangguan, Weufeng

Subjects
*CHEMICALS, *SPECTROSCOPIC imaging, *PHENANTHROLINE, *HYDROGEN bonding, *YTTRIUM
Abstract

In this study, the 4,9 diazafluoren-9-one ligand and [Y(Daf)2Cl3.OH2] complex were synthesized. The interaction of this complex with DNA and bovine serum albumin (BSA) was investigated by UV-vis and fluorescence spectroscopy. The molecular docking method was used to confirm the experimental results, investigate the type of interaction, and determine the binding site. The binding constant and Stern -- Volmer constant were calculated using spectroscopy techniques. The binding constant of the Y-complex with DNA and BSA obtained using the UV-vis technique was 1.61 × 105 M-1 and 0.49 × 105 M-1, while that obtained using the fluorescence method was 3.39 × 105 M-1 and 3.63 × 105 M-1, respectively. The results of experimental and theoretical data showed that the interaction between the yttrium complex and DNA and BSA is driven by the hydrogen bond and van der Waals interaction, respectively. The yttrium complex communicates with DNA via the groove interaction. This complex has high binding energy with bovine serum albumin. In addition, the molecular docking results showed that the complex binds to the IIA subdomain of BSA (site I). Finally, anticancer activity of the yttrium complex was studied on MCF-7 and A549 cell lines by using the MTT method. The IC50 values obtained showed that the yttrium complex possesses anticancer activity. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Multipass friction stir processing of laser-powder bed fusion AlSi10Mg: microstructure and mechanical properties

Author

Heidarzadeh, Akbar, Khorshidi, Mahsa, Mohammadzadeh, Roghayeh, Khajeh, Rasoul, Mofarrehi, Mohammadreza, Javidani, Mousa, Chen, X-Grant, Heidarzadeh, Akbar, Khorshidi, Mahsa, Mohammadzadeh, Roghayeh, Khajeh, Rasoul, Mofarrehi, Mohammadreza, Javidani, Mousa, and Chen, X-Grant

Abstract

The effect of multipass friction stir processing (FSP) on the microstructure and mechanical properties of an AlSi10Mg alloy produced by laser-powder bed fusion was investigated. FSP was performed at a rotational speed of 950 rpm and traverse speed of 85 mm/min. The results indicated that FSP destroyed the coarse grain structure in the as-built AlSi10Mg by generating fine and equiaxed grain structures with shear texture components of A∗ 1 (111) 112 and A∗2 (111) 112, in addition to causing fragmentation and refinement of the Si networks. FSP reduced the tensile strength slightly but significantly improved ductility. One-pass FSP exhibited superior mechanical properties compared with the two- and three-pass scenarios. The higher strength of the one-pass sample was attributed to the strengthening mechanisms induced by the Si particles, which were grown by repeated FSP. The higher ductility of the one-pass sample was explained using the kernel and grain average misorientations. Furthermore, the post-FSP microstructural evolution and fracture behavior of the samples were discussed.

Published
2023
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