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Your search keyword '"Khiabany, Atousa"' showing total 11 results
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11 results on '"Khiabany, Atousa"'

1. Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial

Author

Spicer, James, Basu, Bristi, Montes, Ana, Banerji, Udai, Kristeleit, Rebecca, Miller, Rowan, Veal, Gareth J., Corrigan, Christopher J., Till, Stephen J., Figini, Mariangela, Canevari, Silvana, Barton, Claire, Jones, Paul, Mellor, Sarah, Carroll, Simon, Selkirk, Chris, Nintos, George, Kwatra, Vineet, Funingana, Ionut-Gabriel, Doherty, Gary, Gould, Hannah J., Pellizzari, Giulia, Nakamura, Mano, Ilieva, Kristina M., Khiabany, Atousa, Stavraka, Chara, Chauhan, Jitesh, Gillett, Cheryl, Pinder, Sarah, Bax, Heather J., Josephs, Debra H., and Karagiannis, Sophia N.

Published
2023
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2. Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Author

Bax, Heather J., Chauhan, Jitesh, Stavraka, Chara, Santaolalla, Aida, Osborn, Gabriel, Khiabany, Atousa, Grandits, Melanie, López-Abente, Jacobo, Palhares, Lais C. G. F., Chan Wah Hak, Charleen, Robinson, Alexandra, Pope, Amy, Woodman, Natalie, Naceur-Lombardelli, Cristina, Malas, Sadek, Coumbe, Jack E. M., Nakamura, Mano, Laddach, Roman, Mele, Silvia, Crescioli, Silvia, Black, Anna M., Lombardi, Sara, Canevari, Silvana, Figini, Mariangela, Sayasneh, Ahmad, Tsoka, Sophia, FitzGerald, Kevin, Gillett, Cheryl, Pinder, Sarah, Van Hemelrijck, Mieke, Kristeleit, Rebecca, Ghosh, Sharmistha, Montes, Ana, Spicer, James, Karagiannis, Sophia N., and Josephs, Debra H.

Published
2023
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3. Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes

Author

Graham, Rosalind, primary, Gazinska, Patrycja, additional, Zhang, Birong, additional, Khiabany, Atousa, additional, Sinha, Shubhankar, additional, Alaguthurai, Thanussuyah, additional, Flores-Borja, Fabian, additional, Vicencio, Jose, additional, Beuron, Fabienne, additional, Roxanis, Ioannis, additional, Matkowski, Rafal, additional, Liam-Or, Revadee, additional, Tutt, Andrew, additional, Ng, Tony, additional, Al-Jamal, Khuloud T., additional, Zhou, You, additional, and Irshad, Sheeba, additional

Published
2023
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5. Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes

Author

Bax, Heather J., primary, Chauhan, Jitesh, additional, Stavraka, Chara, additional, Santaolalla, Aida, additional, Osborn, Gabriel, additional, Khiabany, Atousa, additional, Grandits, Melanie, additional, López-Abente, Jacobo, additional, Palhares, Lais C. G. F., additional, Chan Wah Hak, Charleen, additional, Robinson, Alexandra, additional, Pope, Amy, additional, Woodman, Natalie, additional, Naceur-Lombardelli, Cristina, additional, Malas, Sadek, additional, Coumbe, Jack E. M., additional, Nakamura, Mano, additional, Laddach, Roman, additional, Mele, Silvia, additional, Crescioli, Silvia, additional, Black, Anna M., additional, Lombardi, Sara, additional, Canevari, Silvana, additional, Figini, Mariangela, additional, Sayasneh, Ahmad, additional, Tsoka, Sophia, additional, FitzGerald, Kevin, additional, Gillett, Cheryl, additional, Pinder, Sarah, additional, Van Hemelrijck, Mieke, additional, Kristeleit, Rebecca, additional, Ghosh, Sharmistha, additional, Montes, Ana, additional, Spicer, James, additional, Karagiannis, Sophia N., additional, and Josephs, Debra H., additional

Published
2022
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6. IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

Author

Nakamura, Mano, primary, Souri, Elmira Amiri, additional, Osborn, Gabriel, additional, Laddach, Roman, additional, Chauhan, Jitesh, additional, Stavraka, Chara, additional, Lombardi, Sara, additional, Black, Anna, additional, Khiabany, Atousa, additional, Khair, Duaa O., additional, Figini, Mariangela, additional, Winship, Anna, additional, Ghosh, Sharmistha, additional, Montes, Ana, additional, Spicer, James F., additional, Bax, Heather J., additional, Josephs, Debra H., additional, Lacy, Katie E., additional, Tsoka, Sophia, additional, and Karagiannis, Sophia N., additional

Published
2020
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7. Abstract CT141: Phase 1 trial of MOv18, a first-in-class IgE antibody therapy for cancer

Author

Spicer, James, primary, Basu, Bristi, additional, Montes, Ana, additional, Banerji, Udai, additional, Kristeleit, Rebecca, additional, Veal, Gareth J., additional, Corrigan, Christopher, additional, Till, Stephen, additional, Nintos, George, additional, Brier, Timothy, additional, Funingana, Ionut G., additional, Ang, Joo Ern, additional, Zaki, Kam, additional, Griffin, Annie, additional, Barton, Claire, additional, Jones, Paul, additional, Mellor, Sarah, additional, Brook, Susan, additional, Stoddart, Katie, additional, Selkirk, Christopher, additional, Carroll, Simon, additional, Lentfer, Heike, additional, Woodman, Natalie, additional, Pope, Amy, additional, Pellizzari, Giulia, additional, Nakamura, Mano, additional, Ilieva, Kristina M., additional, Khiabany, Atousa, additional, Stavraka, Chara, additional, Gould, Hannah, additional, Chauhan, Jitesh, additional, Bax, Heather, additional, Pinder, Sarah, additional, Josephs, Debra, additional, and Karagiannis, Sophia, additional

Published
2020
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8. Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome

Author

Bax, Heather J., primary, Chauhan, Jitesh, additional, Stavraka, Chara, additional, Khiabany, Atousa, additional, Nakamura, Mano, additional, Pellizzari, Giulia, additional, Ilieva, Kristina M., additional, Lombardi, Sara, additional, Gould, Hannah J., additional, Corrigan, Christopher J., additional, Till, Stephen J., additional, Katugampola, Sidath, additional, Jones, Paul S., additional, Barton, Claire, additional, Winship, Anna, additional, Ghosh, Sharmistha, additional, Montes, Ana, additional, Josephs, Debra H., additional, Spicer, James F., additional, and Karagiannis, Sophia N., additional

Published
2020
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9. Basophil activation test in cancer patient blood evaluating potential hypersensitivity to an anti‐tumor IgE therapeutic candidate

Author

Bax, Heather J., primary, Khiabany, Atousa, additional, Stavraka, Chara, additional, Pellizzari, Giulia, additional, Chan Wah Hak, Charleen, additional, Robinson, Alexandra, additional, Ilieva, Kristina M., additional, Woodman, Natalie, additional, Naceur‐Lombardelli, Cristina, additional, Gillett, Cheryl, additional, Pinder, Sarah, additional, Gould, Hannah J., additional, Corrigan, Christopher J., additional, Till, Stephen J., additional, Katugampola, Sidath, additional, Barton, Claire, additional, Winship, Anna, additional, Ghosh, Sharmistha, additional, Montes, Ana, additional, Josephs, Debra H., additional, Spicer, James F., additional, and Karagiannis, Sophia N., additional

Published
2020
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10. Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma

Author

Khair, Duaa O., primary, Bax, Heather J., additional, Mele, Silvia, additional, Crescioli, Silvia, additional, Pellizzari, Giulia, additional, Khiabany, Atousa, additional, Nakamura, Mano, additional, Harris, Robert J., additional, French, Elise, additional, Hoffmann, Ricarda M., additional, Williams, Iwan P., additional, Cheung, Anthony, additional, Thair, Benjamin, additional, Beales, Charlie T., additional, Touizer, Emma, additional, Signell, Adrian W., additional, Tasnova, Nahrin L., additional, Spicer, James F., additional, Josephs, Debra H., additional, Geh, Jenny L., additional, MacKenzie Ross, Alastair, additional, Healy, Ciaran, additional, Papa, Sophie, additional, Lacy, Katie E., additional, and Karagiannis, Sophia N., additional

Published
2019
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11. A Systematic Review of Surgical and Pathological Outcomes in Patients With a CDH1 Mutation Undergoing Total Gastrectomy.

Author

Khiabany A, Dermanis AA, Liew MS, Ong KR, Kamarajah SK, and Griffiths EA

Abstract

Background: CDH1 (E-cadherin) genetic mutations are associated with a 30%-70% increased lifetime risk of hereditary diffuse gastric cancer (HDGC). Although prophylactic total gastrectomy (PTG) reduces long-term risk of gastric cancer, the associated morbidity and mortality remain unclear. This systematic review aims to characterise postoperative surgical outcomes in patients undergoing total gastrectomy., Methods: A systematic literature search was performed for studies reporting endoscopic surveillance, surgical and pathological outcomes for patients with CDH1 mutation undergoing a total gastrectomy., Results: Thirty-nine studies included 1849 patients, of which 96% had a CDH1 (n = 1777) or CTNNA1 (n = 3) mutation. Endoscopy outcomes were reported for 1640 patients. Cancer foci were identified in 32% (n = 523/1640) and 71% of these patients went on to have a total gastrectomy (n = 369/523). The remaining 78% of patients did not have cancer foci detected on endoscopy (n = 1117/1640). Of these patients, 62% underwent a total gastrectomy (n = 688/1117) and 81% were found to have cancer on surgical histology (n = 556/688). Pathological staging was reported for 790 patients undergoing surgery, of which 68% had pT1 disease (n = 537). Postoperative complications were reported for 430 patients across 23 studies, with the most common complications being anastomotic strictures (25%), anastomotic leaks (13%), wound infections (12%) and pulmonary complications (11%). Only one postoperative death was reported within 30 days., Conclusion: Rates of early cancers are high in CDH1 patients undergoing PTG, highlighting the need for improvement in reliable endoscopic surveillance. Although postoperative mortality in this surgical cohort remains low, high rates of postoperative complications warrant careful patient counselling., (© 2024 Wiley Periodicals LLC.)

Published
2024
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