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145 results on '"Khattak, Saadullah"'

9. List of contributors

Author

Abid, Mehwish, primary, Adetunji, Charles Oluwaseun, additional, Adetunji, Juliana Bunmi, additional, Ajayi, Olulope Olufemi, additional, Ajiboye, Modupe Doris, additional, Akgönüllü, Semra, additional, Ariyasena, Devaka Dharmapriya, additional, Ashfaq, Muhammad, additional, Asif, Muhammad, additional, Bakhshpour, Monireh, additional, Balafouti, Anastasia, additional, Bandara, Chamila S., additional, Bano, Iqra, additional, Batool, Maria, additional, Batool, Saira, additional, Bereli, Nilay, additional, Butt, Usman Dawood, additional, Chatterjee, Sayandev, additional, Czerwinski, Kenneth R., additional, Das, Sangita, additional, Dauda, Wadazani, additional, de Jesus, Roberta Anjos, additional, Denizli, Adil, additional, Fan, Zhijin, additional, Ferreira, Luiz Fernando Romanholo, additional, Figueiredo, Renan Tavares, additional, Fitzgerald, Hilary A., additional, Gamage, Navin, additional, Ghazanfar, Shakira, additional, Gunaratne, Jayamini C., additional, Hanif, Sumaira, additional, Hassan, Sadaf Ul, additional, Huma, Tanzeel, additional, Huma, Tbassum, additional, Ijabadeniyi, Oluwatosin Ademola, additional, Imran, Muhammad, additional, Inobeme, Abel, additional, Iqbal, Amna, additional, Jabbar, Tania, additional, Jiang, Cheng, additional, Khaliq, Kashaf, additional, Khaliq, Muniba, additional, Khattak, Saadullah, additional, Lakes, Andrew L., additional, Liao, Zuolei, additional, Ludwig, Russell C., additional, Mahmood, Marryam, additional, Mathew, John Tsado, additional, McBride, Katie M., additional, Mohsan, Syed Agha Hassnain, additional, Muhammad, Pir, additional, Mumtaz, Sumaira, additional, Mustafa, Ghulam, additional, Naqvi, Syed Ali Raza, additional, Nascimento, Victor Ruan Silva, additional, Nazar, Muhammad Faizan, additional, Nelumdeniya, Rumesh M., additional, Ogundolie, Frank Abimbola, additional, Olaniyan, Olugbemi Tope, additional, Oliveira, Ícaro Mota, additional, Padi, DhanaLakshmi, additional, Perera, Ishanie Rangeeka, additional, Pippa, Natassa, additional, Pispas, Stergios, additional, Pola, Sudhakar, additional, Pratim Das, Partha, additional, Ranatunga, Harith, additional, Rehman, Fawad Ur, additional, Saalbach, Klaus P., additional, Saleem, Muhammad Atif, additional, Sanapala, Pavani, additional, Selianitis, Dimitrios, additional, Sentoukas, Theodore, additional, Shahzad, Sohail Anjum, additional, Sherazi, Tauqir A., additional, Siddique, Muhammad Yasir, additional, Skandalis, Athanasios, additional, Sumrra, Sajjad Hussain, additional, Tawakkul, Nosheen, additional, Thomas, Sabu, additional, Thrikawala, Savani Weerahewa, additional, Titilayo, Olotu, additional, Topçu, Aykut Arif, additional, Udayana, Ranatunga, additional, Vlasenko, Vladislav P., additional, Waruni, Keshiya, additional, Zafar, Muhammad Nadeem, additional, and Zubair, Muhammad, additional

Published
2023
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16. Exploring the antibacterial and dermatitis-mitigating properties of chicken egg white-synthesized zinc oxide nano whiskers.

Author

Abdikakharovich, Sidikov Akmal, Rauf, Mohd A., Khattak, Saadullah, Shah, Junaid Ali, Al-Keridis, Lamya Ahmed, Alshammari, Nawaf, Saeed, Mohd, and Igorevich, Sadykov Aslan

Subjects
WHISKERS, ZINC oxide, INFRARED spectroscopy, COMMUNICABLE diseases, X-ray spectroscopy, EGG whites, EGGS
Abstract

Introduction: Zinc oxide nanoparticles (ZnO-NPs) have garnered considerable interest in biomedical research primarily owing to their prospective therapeutic implications in combatting pathogenic diseases and microbial infections. The primary objective of this study was to examine the biosynthesis of zinc oxide nanowhiskers (ZnO-NWs) using chicken egg white (albumin) as a bio-template. Furthermore, this study aimed to explore the potential biomedical applications of ZnO NWs in the context of infectious diseases. Methods: The NWs synthesized through biological processes were observed using electron microscopy, which allowed for detailed examination of their characteristics. The results of these investigations indicated that the NWs exhibited a size distribution ranging from approximately 10 to 100 nm. Fouriertransform infrared spectroscopy (FTIR) and scanning electron microscopyenergy dispersive X-ray spectroscopy (SEM-EDX) mapping analyses successfully corroborated the size, dimensions, and presence of biological constituents during their formation. In this study, XTT assay and confocal imaging were employed to provide evidence of the efficacy of ZnO-NWs in the eradication of bacterial biofilms. The target bacterial strains were Staphylococcus aureus and Escherichia coli. Furthermore, we sought to address pertinent concerns regarding the biocompatibility of the ZnO-NWs. This was achieved through comprehensive evaluation of the absence of cytotoxicity in normal HEK-293T and erythrocytes. Results: The findings of this investigation unequivocally confirmed the biocompatibility of the ZnO-NWs. The biosynthesized ZnO-NWs demonstrated a noteworthy capacity to mitigate the dermatitis-induced consequences induced by Staphylococcus aureus in murine models after a therapeutic intervention lasting for one week. Discussion: This study presents a comprehensive examination of the biosynthesis of zinc oxide nanowhiskers (ZnO-NWs) derived from chicken egg whites. These findings highlight the considerable potential of biosynthesized ZnO-NWs as a viable option for the development of therapeutic agents targeting infectious diseases. The antibacterial efficacy of ZnO-NWs against both susceptible and antibiotic-resistant bacterial strains, as well as their ability to eradicate biofilms, suggests their promising role in combating infectious diseases. Furthermore, the confirmed biocompatibility of ZnO-NWs opens avenues for their safe use in biomedical applications. Overall, this research underscores the therapeutic promise of ZnO-NWs and their potential significance in future biomedical advancements. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Vaccinomics-based next-generation multi-epitope chimeric vaccine models prediction against Leishmania tropica - a hierarchical subtractive proteomics and immunoinformatics approach

Author

Aiman, Sara, primary, Ahmad, Abbas, additional, Khan, Azmat Ali, additional, Alanazi, Amer M., additional, Samad, Abdus, additional, Ali, Syed Luqman, additional, Li, Chunhua, additional, Ren, Zhiguang, additional, Khan, Asifullah, additional, and Khattak, Saadullah, additional

Published
2023
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25. The double-edged sword role of hydrogen sulfide in hepatocellular carcinoma.

Author

Huijie Zhao, Yanting Zhang, Xiaodi Fu, Chaoren Chen, Khattak, Saadullah, and Honggang Wang

Subjects
HEPATOCELLULAR carcinoma, HYDROGEN sulfide, CARBON monoxide, DNA methylation, CELL cycle, LIVER tumors
Abstract

With an increasing worldwide prevalence, hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver in the world. It is also the primary reason for cancer-related death in the world. The pathogenesis of HCC is complex, such as DNA methylation changes, immune regulatory disorders, cell cycle disorders, chromosomal instability, and so on. Although many studies have been conducted on HCC, the molecular mechanisms of HCC are not completely understood. At present, there is no effective treatment for HCC. Hydrogen sulfide (H2S) has long been regarded as a toxic gas with the smell of rotten eggs, but recent studies have shown that it is an important gasotransmitter along with carbon monoxide (CO) and nitric oxide (NO). Increasing evidence indicates that H2S has multiple biological functions, such as anti-inflammation, anti-apoptosis, anti-oxidative stress, and so on. Recently, a lot of evidence has shown that H2S has a "double-edged sword" effect in HCC, but the mechanism is not fully understood. Here, we reviewed the progress on the role and mechanism of H2S in HCC in recent years, hoping to provide a theoretical reference for future related research. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Assessment of Attitudes and Intentions towards COVID-19 Vaccines and Associated Factors among General Populations of Pakistan: A Cross-Sectional Study

Author

Khattak, Saadullah, primary, Idrees, Muhammad, additional, Iqbal, Hafiza Iqra, additional, Khan, Maqbool, additional, Assad, Nasir, additional, Khan, Muhammad Naeem, additional, Yousaf, Muhammad Tufail, additional, Farooq, Muhammad, additional, Yang, Chang-Yong, additional, Wu, Dong-Dong, additional, and Ji, Xin-Ying, additional

Published
2022
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32. Define the Two Molecular Subtypes of Epithelioid Malignant Pleural Mesothelioma

Author

Saddozai, Umair Ali Khan, primary, Wang, Fengling, additional, Khattak, Saadullah, additional, Akbar, Muhammad Usman, additional, Badar, Muhammad, additional, Khan, Nazeer Hussain, additional, Zhang, Lu, additional, Zhu, Wan, additional, Xie, Longxiang, additional, Li, Yongqiang, additional, Ji, Xinying, additional, and Guo, Xiangqian, additional

Published
2022
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36. Knowledge, Attitude, and Perception of Cancer Patients towards COVID-19 in Pakistan: A Cross-Sectional Study

Author

Khattak, Saadullah, primary, Faheem, Muhammad, additional, Nawaz, Bilawal, additional, Khan, Maqbool, additional, Khan, Nazeer Hussain, additional, Ullah, Nadeem, additional, Khan, Taj Ali, additional, Khan, Rahat Ullah, additional, Haleem, Kashif Syed, additional, Ren, Zhi-Guang, additional, Wu, Dong-Dong, additional, and Ji, Xin-Ying, additional

Published
2022
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39. Hydrogen Sulfide Biology and Its Role in Cancer

Author

Khattak, Saadullah, primary, Rauf, Mohd Ahmar, additional, Khan, Nazeer Hussain, additional, Zhang, Qian-Qian, additional, Chen, Hao-Jie, additional, Muhammad, Pir, additional, Ansari, Mohammad Azam, additional, Alomary, Mohammad N., additional, Jahangir, Muhammad, additional, Zhang, Chun-Yang, additional, Ji, Xin-Ying, additional, and Wu, Dong-Dong, additional

Published
2022
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40. Role of Hydrogen Sulfide in Oral Disease

Author

Wu, Dong-Dong, Ngowi, Ebenezeri Erasto, Zhai, Yuan-Kun, Wang, Yi-Zhen, Khan, Nazeer Hussain, Kombo, Ahmad Fadhil, Khattak, Saadullah, Li, Tao, and Ji, Xin-Ying

Subjects
Article Subject
Abstract

Oral diseases are among the most common human diseases yet less studied. These diseases affect both the physical, mental, and social health of the patients resulting in poor quality of life. They affect all ages, although severe stages are mostly observed in older individuals. Poor oral hygiene, genetics, and environmental factors contribute enormously to the development and progression of these diseases. Although there are available treatment options for these diseases, the recurrence of the diseases hinders their efficiency. Oral volatile sulfur compounds (VSCs) are highly produced in oral cavity as a result of bacteria activities. Together with bacteria components such as lipopolysaccharides, VSCs participate in the progression of oral diseases by regulating cellular activities and interfering with the immune response. Hydrogen sulfide (H2S) is a gaseous neurotransmitter primarily produced endogenously and is involved in the regulation of cellular activities. The gas is also among the VSCs produced by oral bacteria. In numerous diseases, H2S have been reported to have dual effects depending on the cell, concentration, and donor used. In oral diseases, high production and subsequent utilization of this gas have been reported. Also, this high production is associated with the progression of oral diseases. In this review, we will discuss the production of H2S in oral cavity, its interaction with cellular activities, and most importantly its role in oral diseases.

Published
2022
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41. Assessment of General Populations Knowledge, Attitude, and Perceptions Toward the Coronavirus Disease (COVID-19): A Cross-Sectional Study From Pakistan

Author

Khattak, Saadullah, primary, Khan, Maqbool, additional, Usman, Tahir, additional, Ali, Johar, additional, Wu, Dong-Xing, additional, Jahangir, Muhammad, additional, Haleem, Kashif, additional, Muhammad, Pir, additional, Rauf, Mohd Ahmar, additional, Saddique, Kamran, additional, Khan, Nazeer Hussain, additional, Li, Tao, additional, Wu, Dong-Dong, additional, and Ji, Xin-Ying, additional

Published
2021
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45. The Role of Hydrogen Sulfide in Respiratory Diseases

Author

Khattak, Saadullah, primary, Zhang, Qian-Qian, additional, Sarfraz, Muhammad, additional, Muhammad, Pir, additional, Ngowi, Ebenezeri Erasto, additional, Khan, Nazeer Hussain, additional, Rauf, Saqib, additional, Wang, Yi-Zhen, additional, Qi, Hui-Wen, additional, Wang, Di, additional, Afzal, Attia, additional, Ji, Xin-Ying, additional, and Wu, Dong-Dong, additional

Published
2021
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46. Nanomedicine: A Promising Way to Manage Alzheimer’s Disease

Author

Khan, Nazeer Hussain, primary, Mir, Maria, additional, Ngowi, Ebenezeri Erasto, additional, Zafar, Ujala, additional, Khakwani, Muhammad Mahtab Aslam Khan, additional, Khattak, Saadullah, additional, Zhai, Yuan-Kun, additional, Jiang, En-She, additional, Zheng, Meng, additional, Duan, Shao-Feng, additional, Wei, Jian-She, additional, Wu, Dong-Dong, additional, and Ji, Xin-Ying, additional

Published
2021
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47. Impact of the factors shaping gut microbiota on obesity

Author

Ngowi, Ebenezeri Erasto, primary, Wang, Yi‐Zhen, additional, Khattak, Saadullah, additional, Khan, Nazeer Hussain, additional, Mahmoud, Salma Sayed Mohamed, additional, Helmy, Yasmeen Ahmed Saleheldin Hassan, additional, Jiang, Qi‐Ying, additional, Li, Tao, additional, Duan, Shao‐Feng, additional, Ji, Xin‐Ying, additional, and Wu, Dong‐Dong, additional

Published
2021
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48. The Potential of Hydrogen Sulfide Donors in Treating Cardiovascular Diseases

Author

Wang, Yi-Zhen, primary, Ngowi, Ebenezeri Erasto, additional, Wang, Di, additional, Qi, Hui-Wen, additional, Jing, Mi-Rong, additional, Zhang, Yan-Xia, additional, Cai, Chun-Bo, additional, He, Qing-Lin, additional, Khattak, Saadullah, additional, Khan, Nazeer Hussain, additional, Jiang, Qi-Ying, additional, Ji, Xin-Ying, additional, and Wu, Dong-Dong, additional

Published
2021
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49. Role of hydrogen sulfide donors in cancer development and progression

Author

Ngowi, Ebenezeri Erasto, primary, Afzal, Attia, additional, Sarfraz, Muhammad, additional, Khattak, Saadullah, additional, Zaman, Shams Uz, additional, Khan, Nazeer Hussain, additional, Li, Tao, additional, Jiang, Qi-Ying, additional, Zhang, Xin, additional, Duan, Shao-Feng, additional, Ji, Xin-Ying, additional, and Wu, Dong-Dong, additional

Published
2021
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50. Roles of Hydrogen Sulfide Donors in Common Kidney Diseases

Author

Ngowi, Ebenezeri Erasto, primary, Sarfraz, Muhammad, additional, Afzal, Attia, additional, Khan, Nazeer Hussain, additional, Khattak, Saadullah, additional, Zhang, Xin, additional, Li, Tao, additional, Duan, Shao-Feng, additional, Ji, Xin-Ying, additional, and Wu, Dong-Dong, additional

Published
2020
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