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2. Defining necrotizing enterocolitis: current difficulties and future opportunities

Author

Patel, Ravi Mangal, Ferguson, Joanne, McElroy, Steven J, Khashu, Minesh, and Caplan, Michael S

Subjects
Rare Diseases, Pediatric, Orphan Drug, Perinatal Period - Conditions Originating in Perinatal Period, Infant Mortality, Preterm, Low Birth Weight and Health of the Newborn, Good Health and Well Being, Centers for Disease Control and Prevention, U.S., Consensus, Enterocolitis, Necrotizing, Female, Humans, Infant, Infant, Newborn, Infant, Newborn, Diseases, Infant, Premature, Infant, Premature, Diseases, Male, Neonatology, Risk, Risk Factors, United Kingdom, United States, Paediatrics and Reproductive Medicine, Public Health and Health Services, Pediatrics
Abstract

Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in hospitalized infants. First classified through Bell staging in 1978, a number of additional definitions of NEC have been proposed in the subsequent decades. In this review, we summarize eight current definitions of NEC, and explore similarities and differences in clinical signs and radiographic features included within these definitions, as well as their limitations. We highlight the importance of a global consensus on defining NEC to improve NEC research and outcomes, incorporating input from participants at an international NEC conference. We also highlight the important role of patient-families in helping to redefine NEC.

Published
2020

3. Prenatal maternal mental health and resilience in the United Kingdom during the SARS-CoV-2 pandemic: a cross- national comparison.

Author

Datye, Swarali, Smiljanic, Marko, Shetti, Rohan, MacRae-Miller, Alison, van Teijlingen, Edwin, Vinayakarao, Latha, Peters, Eva M. J., Lebel, Catherine, Tomfohr-Madsen, Lianne, Giesbrecht, Gerald, Khashu, Minesh, and Conrad, Melanie L.

Subjects
PREGNANT women, COVID-19 pandemic, MENTAL illness, PREGNANCY outcomes, MENTAL depression
Abstract

Introduction: Prenatal mental health problems are associated with morbidity for the pregnant person, and their infants are at long-term risk for poor health outcomes. We aim to explore how the SARS-CoV-2 pandemic affected the mental health of pregnant people in the United Kingdom (UK), and to further identify resilience factors which may have contributed to varying mental health outcomes. We also aim to examine the quality of antenatal care provided during the pandemic in the UK and to identify potential inadequacies to enhance preparedness for future events. Methods: During June-November 2020, we recruited 3666 individuals in the UK for the EPPOCH pregnancy cohort (Maternal mental health during the COVID-19 pandemic: Effect of the Pandemic on Pregnancy Outcomes and Childhood Health). Participants were assessed for depression, anxiety, anger and pregnancy-related anxiety using validated scales. Additionally, physical activity, social support, individualized support and personal coping ability of the respondents were assessed as potential resilience factors. Results: Participants reported high levels of depression (57.05%), anxiety (58.04%) and anger (58.05%). Higher levels of social and individualized support and personal coping ability were associated with lower mental health challenges. Additionally, pregnant individuals in the UK experienced higher depression during the pandemic than that reported in Canada. Finally, qualitative analysis revealed that restrictions for partners and support persons during medical appointments as well as poor public health communication led to increased mental health adversities and hindered ability to make medical decisions. Discussion: This study revealed increased mental health challenges among pregnant individuals in the UK during the SARS-CoV-2 pandemic. These results highlight the need for reassessing the mental health support measures available to pregnant people in the UK, both during times of crisis and in general. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Prenatal maternal mental health and resilience in the United Kingdom during the SARS-CoV-2 pandemic: a crossnational comparison.

Author

Datye, Swarali, Smiljanic, Marko, Shetti, Rohan, MacRae-Miller, Alison, van Teijlingen, Edwin, Vinayakarao, Latha, Peters, Eva M. J., Lebel, Catherine, Tomfohr-Madsen, Lianne, Giesbrecht, Gerald, Khashu, Minesh, and Conrad, Melanie L.

Subjects
PREGNANT women, COVID-19 pandemic, MENTAL illness, PREGNANCY outcomes, MENTAL depression
Abstract

Introduction: Prenatal mental health problems are associated with morbidity for the pregnant person, and their infants are at long-term risk for poor health outcomes. We aim to explore how the SARS-CoV-2 pandemic affected the mental health of pregnant people in the United Kingdom (UK), and to further identify resilience factors which may have contributed to varying mental health outcomes. We also aim to examine the quality of antenatal care provided during the pandemic in the UK and to identify potential inadequacies to enhance preparedness for future events. Methods: During June-November 2020, we recruited 3666 individuals in the UK for the EPPOCH pregnancy cohort (Maternal mental health during the COVID-19 pandemic: Effect of the Pandemic on Pregnancy Outcomes and Childhood Health). Participants were assessed for depression, anxiety, anger and pregnancy-related anxiety using validated scales. Additionally, physical activity, social support, individualized support and personal coping ability of the respondents were assessed as potential resilience factors. Results: Participants reported high levels of depression (57.05%), anxiety (58.04%) and anger (58.05%). Higher levels of social and individualized support and personal coping ability were associated with lower mental health challenges. Additionally, pregnant individuals in the UK experienced higher depression during the pandemic than that reported in Canada. Finally, qualitative analysis revealed that restrictions for partners and support persons during medical appointments as well as poor public health communication led to increased mental health adversities and hindered ability to make medical decisions. Discussion: This study revealed increased mental health challenges among pregnant individuals in the UK during the SARS-CoV-2 pandemic. These results highlight the need for reassessing the mental health support measures available to pregnant people in the UK, both during times of crisis and in general. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Navigating toward Neonatology: Neonatal Bacterial Meningitis.

Author

Hopkins, Benjamin and Khashu, Minesh

Subjects
*BACTERIAL meningitis, *RISK assessment, *NEONATOLOGY, *DISEASE duration, *INFECTION control, *AMPICILLIN, *DISEASES, *GENTAMICIN, *STREPTOCOCCAL diseases, *EARLY diagnosis, *LENGTH of stay in hospitals, *DISEASE risk factors, *CHILDREN
Abstract

The article focuses on neonatal bacterial meningitis, a life-threatening infection with high mortality and morbidity rates in neonates. Topics discussed include the leading causes of meningitis, particularly Group B Streptococcus, risk factors associated with infection, and the critical importance of early diagnosis and treatment.

Published
2024

9. Variations in Neonatal Length of Stay of Babies Born Extremely Preterm: An International Comparison Between iNeo Networks

Author

Lui, Kei, Marshall, Peter, Schmidt, Peter, Dhawan, Anjali, Korostenski, Larissa, Travadi, Javeed Travadi, Sharp, Mary, Gill, Andy, Pillow, Jane, Stack, Jacqueline, Birch, Pita, Nothdurft, Karen, Cooke, Lucy, Casalaz, Dan, Holberton, Jim, Stewart, Alice, Downe, Lyn, Stewart, Michael, Berry, Andrew, Hunt, Rod, Morris, Peter, Paoli, Tony De, Bolisetty, Srinivas, Paradisis, Mary, Greenhalgh, Mark, Koorts, Pieter, Kuschel, Carl, Jacobs, Sue, Doyle, Lex, Craven, John, Numa, Andrew, Carlisle, Hazel, Badawi, Nadia, Popat, Himanshu, Koh, Guan, Davis, Jonathan, Luig, Melissa, Headley, Bevan, Andersen, Chad, Ng, Linda, Chambers, Georgina, Austin, Nicola, Lynn, Adrienne, Darlow, Brian, Edmonds, Liza, Mildenhall, Lindsay, Buksh, Mariam, Battin, Malcolm, Boom, Jutta van den, Richardson, Vaughan, Barker, David, Hammond, Barbara, Rajadurai, Victor Samuel, Lam, Simon, Fung, Genevieve, Shah, Prakesh S., Beltempo, Marc, Kanungo, Jaideep, Ting, Joseph, Cieslak, Zenon, Sherlock, Rebecca, Mehrem, Ayman Abou, Toye, Jennifer, Aziz, Khalid, Fajardo, Carlos, Bodani, Jaya, Strueby, Lannae, Seshia, Mary, Louis, Deepak, Alvaro, Ruben, Mukerji, Amit, Da Silva, Orlando, Adie, Mohammad, Lee, Kyong-Soon, Ng, Eugene, Lemyre, Brigitte, Daboval, Thierry, Khurshid, Faiza, Pelausa, Ermelinda, Barrington, Keith, Lapoint, Anie, Ethier, Guillaume, Drolet, Christine, Piedboeuf, Bruno, Claveau, Martine, St-Hilaire, Marie, Bertelle, Valerie, Masse, Edith, Canning, Roderick, Makary, Hala, Ojah, Cecil, Monterrosa, Luis, Emberley, Julie, Afifi, Jehier, Kajetanowicz, Andrzej, Lee, Shoo K., Metsäranta, Marjo, Lehtonen, Liisa, Tammela, Outi, Sankilampi, Ulla, Saarela, Timo, Morag, Iris, Zangen, Shmuel, Smolkin, Tatyana, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Omari, Hussam, Tov-Friedman, Smadar Even, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Kugelman, Amir, Shinwell, Eric, Klinger, Gil, Nijim, Yousif, Bin-Nun, Alona, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Oron, Anat, Bakhrakh, Lev, Hattori, Satoshi, Shirai, Masaru, Ishioka, Toru, Mori, Toshihiko, Amizuka, Takasuke, Huchimukai, Toru, Yoshida, Hiroshi, Sasaki, Ayako, Shimizu, Junichi, Nakamura, Toshihiko, Maruyama, Mami, Matsumoto, Hiroshi, Hosokawa, Shinichi, Taki, Atsuko, Nakagawa, Machiko, Ko, Kyone, Uozumi, Azusa, Nakata, Setsuko, Shimazaki, Akira, Yoda, Tatsuya, Numata, Osamu, Imamura, Hiroaki, Kobayashi, Azusa, Tokuriki, Shuko, Uchida, Yasushi, Arai, Takahiro, Ito, Mitsuhiro, Ieda, Kuniko, Ono, Toshiyuki, Hayashi, Masashi, Maki, Kanemasa, Yamakawa, MieToru, Kawai, Masahiko, Fujii, Noriko, Shiomi, Kozue, Nozaki, Koji, Wada, Hiroshi, Kim, Taho, Tokunaga, Yasuyuki, Takatera, Akihiro, Oshima, Toshio, Sumida, Hiroshi, Michinomae, Yae, Kusumoto, Yoshio, Yoshimoto, Seiji, Morisawa, Takeshi, Ohashi, Tamaki, Takahashi, Yukihiro, Sugimoto, Moriharu, Ono, Noriaki, Miyagawa, Shinichiro, Saijo, Takahiko, Yamagami, Takashi, Koyano, Kosuke, Kobayashi, Shoko, Kanda, Takeshi, Sakemi, Yoshihiro, Aoki, Mikio, Iida, Koichi, Goshi, Mitsushi, Maruyama, Yuko, Avila-Alvarez, Alejandro, Fernandez-Trisac, José Luis, Pico, M<ce:sup loc='post">a</ce:sup> Luz Couce, Fernández Seara, María José, Gutiérrez, Andrés Martínez, Vizcaíno, Carolina, Iglesias, Miriam Salvador, Zaplana, Honorio Sánchez, Colomer, Belén Fernández, García López, José Enrique, Mozo, Rafael García, González Martínez, M. Teresa, Sebastián, M<ce:sup loc='post">a</ce:sup> Dolores Muro, Carbonell, Marta Balart, Barnusell, Joan Badia, Puiggròs, Mònica Domingo, Aloy, Josep Figueras, Mussons, Francesc Botet, Sanz, Israel Anquela, Galiana, Gemma Ginovart, Coroleu, W., Iriondo, Martin, Vilella, Laura Castells, Porta, Roser, Demestre, Xavier, Nadal, Silvia Martínez, de Frutos Martínez, Cristina, López Cuesta, María Jesús, Mora, Dolores Esquivel, Tardío, Joaquín Ortiz, Benavente, Isabel, Alonso, Almudena, Olmos, Ramón Aguilera, García Cabezas, Miguel A., Jiménez, M<ce:sup loc='post">a</ce:sup> Dolores Martínez, Caballero, M<ce:sup loc='post">a</ce:sup> Pilar Jaraba, Díaz, M<ce:sup loc='post">a</ce:sup> Dolores Ordoñez, Fagundo, Alberto Trujillo, Canals, Lluis Mayol, García-Muñoz Rodrigo, Fermín, Martí, Lourdes Urquía, Moreno Galdo, María Fernanda, Suazo, José Antonio Hurtado, López, Eduardo Narbona, Fernández, José Uberos, Cortajarena Altuna, Miguel A., Zuriarrain, Oihana Muga, Navarro, David Mora, Domínguez, María Teresa, Ruiz del Prado, M<ce:sup loc='post">a</ce:sup> Yolanda, Díez, Inés Esteban, Palau Benavides, María Teresa, Lapeña, Santiago, Prada, Teresa, Mir, Eduard Soler, Sánchez, Araceli Corredera, Vega, Enrique Criado, Prado, Náyade del, Fernández, Cristina, Vilaplana, Lucía Cabanillas, Pérez, Irene Cuadrado, Gómez, Luisa López, Comeche, Laura Domingo, Martín, Isabel Llana, Armengod, Carmen González, Labián, Carmen Muñoz, Muñoz, M<ce:sup loc='post">a</ce:sup> José Santos, Bravo, Dorotea Blanco, Pérez, Vicente, Fernández, M<ce:sup loc='post">a</ce:sup> Dolores Elorza, González, Celia Díaz, Segura, Susana Ares, Azorín, Manuela López, Jimenez, Ana Belén, Sánchez-Tamayo, Tomás, Moreno, Elías Tapia, González, María, Sánchez Martínez, José Enrique, Lloreda García, José María, Orayen, Concepción Goñi, González, Javier Vilas, Albo, María Suárez, Colmenero, Eva González, Gutiérrez González, Elena Pilar, Vacas del Arco, Beatriz, Fernández, Josefina Márquez, Gordillo, Laura Acosta, Asensio, Mercedes Granero, Díaz, Carmen Macías, Albújar, Mar, Jorge, Pedro Fuster, Romero, Sabina, Falero, Mónica Rivero, Escobar Izquierdo, Ana Belén, Capell, Javier Estañ, Macián, M<ce:sup loc='post">a</ce:sup> Isabel Izquierdo, Vicente, M<ce:sup loc='post">a</ce:sup> Mar Montejo, Caballero, Raquel Izquierdo, Martínez, M<ce:sup loc='post">a</ce:sup> Mercedes, Euba, Aintzane, Serna, Amaya Rodríguez, López de Heredia Goya, Juan María, Legorburu, Alberto Pérez, Amorós, Ana Gutiérrez, Marugán Isabel, Víctor Manuel, González, Natalio Hernández, Gracia, Segundo Rite, Faci, M<ce:sup loc='post">a</ce:sup> Purificación Ventura, Villagrasa, M<ce:sup loc='post">a</ce:sup> Pilar Samper, Kofron, Jiri, Brodd, Katarina Strand, Odlind, Andreas, Alberg, Lars, Arwehed, Sofia, Hafström, Ola, Kasemo, Anna, Nederman, Karin, Åhman, Lars, Ingemarsson, Fredrik, Petersson, Henrik, Thurn, Pernilla, Albinsson, Eva, Selander, Bo, Abrahamsson, Thomas, Heimdahl, Ingela, Sveinsdottir, Kristbjorg, Wejryd, Erik, Hedlund, Anna, Söderberg, Maria Katarina, Navér, Lars, Brune, Thomas, Bäckström, Jens, Robinson, Johan, Farooqi, Aijaz, Normann, Erik, Fredriksson, Magnus, Palm, Anders, Rosenqvist, Urban, Walde, Bengt, Hagman, Cecilia, Ohlin, Andreas, Florell, Rein, Smedsaas-Löfvenberg, Agneta, Adams, Mark, Meyer, Philipp, Kusche, Rachel, Schulzke, Sven, Nelle, Mathias, Wagner, Bendicht, Riedel, Thomas, Kaczala, Grégoire, Pfister, Riccardo E., Tolsa, Jean-François, Roth, Matthias, Stocker, Martin, Laubscher, Bernhard, Malzacher, Andreas, Micallef, John P., Hegi, Lukas, Bassler, Dirk, Arlettaz, Romaine, Bernet, Vera, Dani, Carlo, Fiorini, Patrizio, Ghirri, Paolo, Tomasini, Barbara, Mittal, Anita, Kefas, Jonathan, Kamalanathan, Anand, Grosdenier, Michael, Dewhurst, Christopher, Bontea, Andreea, Webb, Delyth, Garr, Ross, Hassan, Ahmed, Ambadkar, Priyadarshan, Dyke, Mark, McDevitt, Katharine, Rewitzky, Glynis, D'Amore, Angela, Kamath, P., Settle, Paul, Maddock, Natasha, Edi-Osagie, Ngozi, Zipitis, Christos, Heal, Carrie, Birch, Jacqeline, Hasib, Abdul, Soe, Aung, Abdul-Malik, Bushra, Kisat, Hamudi, Vasu, Vimal, Sivashankar, Savi, Gupta, Richa, Rawlingson, Chris, Wickham, Tim, Theron, Marice, Kendall, Giles, Gupta, Aashish, Aladangady, Narendra, Ali, Imdad, Jain, Neeraj, Mannan, Khalid, Murthy, Vadivelam, Sullivan, Caroline, Chuang, Shu-Ling, Bate, Tristan, Tyszcuzk, Lidia, Lee, Geraint, Obi, Ozioma, Chang, John, Pai, Vinay, Huddy, Charlotte, Yasin, Salim, Nicholl, Richard, Pandey, Poornima, Cusack, Jonathan, Kairamkonda, Venkatesh, Muogbo, Dominic, Harry, Liza, Surana, Pinki, Broggio, Penny, Pillay, Tilly, Deshpande, Sanjeev, Mahadevan, Moore, Alison, Bastani, Porus, Garbash, Mehdi, Lal, Mithilesh, Abu-Harb, Majd, Allwood, Alex, Selter, Michael, Munyard, Paul, Bartle, David, Paul, Siba, Whincup, Graham, Rekha, Sanghavi, Amess, Philip, Obi, Ben, Reynolds, Peter, Misra, Indranil, De Halpert, Peter, Salgia, Sanjay, Sanghavi, Rekha, Paul, Nicola, Deketelaere, Abby, Khashu, Minesh, Johnson, Mark, Groves, Charlotte, Baird, Jim, Brennan, Nick, Vamvakiti, Katia, McIntyre, John, Holman, Jennifer, Jones, Stephen, Pike, Alison, Cairns, Pamela, Eaton, Megan, Schwarz, Karin, Gibson, David, Miall, Lawrence, Krishnamurthy, Dr, Narayanan, Sankara, Seaton, Sarah E., Draper, Elizabeth S., Kusuda, Satoshi, Håkansson, Stellan, Helenius, Kjell, Reichman, Brian, Vento, Maximo, Darlow, Brian A., Rusconi, Franca, Isayama, Tetsuya, Norman, Mikael, Yang, Junmin, and Modi, Neena

Published
2021
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18. Neonatal Outcomes of Very Low Birth Weight and Very Preterm Neonates: An International Comparison

Author

Badawi, Nadia, Marshall, Peter, Craven, Paul, Simmer, Karen, Stack, Jacqueline, Casalaz, Dan, Carse, Elizabeth, Cooke, Lucy, Shingde, Vijay, Cartwright, David, Hunt, Rod, Kilburn, Charles, Dargaville, Peter, Lui, Kei, Paradisis, Mary, Rieger, Ingrid, Kuschel, Carl, Numa, Andrew, Carlisle, Hazel, Koh, Guan, Andersen, Chad, Luig, Melissa, Austin, Nicola, Broadbent, Roland, Mildenhall, Lindsay, Battin, Malcolm, Bourchier, David, Richardson, Vaughan, Synnes, Anne, Rouvinez-Bouali, Nicole, Piedboeuf, Bruno, Bulleid, Barbara, Yee, Wendy, Singhal, Nalini, Harrison, Adele, Tan-Dy, Cherrie, Shivananda, Sandesh, Tan, Kenneth, James, Andrew, Seshia, Molly, Barrington, Keith, Lefebvre, Francine, McMillan, Doug, Andrews, Wayne, Kovacs, Lajos, Dow, Kimberly, Clarke, Maxine, Riley, Patricia, Shah, Prakesh, Ohlsson, Arne, Aziz, Khalid, Peliowski, Abraham, Cieslak, Zenon, Sorokan, Todd, Kalapesi, Zarin, Ninan, Abraham, Sankaran, Koravangattu, Faucher, Daniel, Cronin, Gerarda, Canning, Roderick, da Silva, Orlando, Lee, David, Ojah, Cecil, Dunn, Michael, Heymann, Eli, Zangen, Shmuel, Kushnir, Amir, Mimouni, Francis, Bader, David, Rothschild, Avi, Strauss, Zipora, Felszer, Clari, Jeryes, Jamalia, Even Tov-Friedman, Smadar, Bar-Oz, Benjamin, Feldman, Michael, Saad, Nizar, Flidel-Rimon, Orna, Weisbrod, Meir, Lubin, Daniel, Litmanovitz, Ita, Blazer, Shraga, Shinwell, Eric, Sirota, Leah, Nijim, Yousif, Golan, Agneta, Mandel, Dror, Fleisher-Sheffer, Vered, Kohelet, David, Bakhrakh, Lev, Hattori, Satoshi, Konishi, Shohei, Amizuka, Takasuke, Kasai, Takeo, Takahasi, Ritsuko, Arai, Hirokazu, Sato, Maki, Miyazono, Yayoi, Shimizu, Junichi, Suzumura, Hiroshi, Kono, Yumi, Inoue, Takahiro, Miyabayashi, Hiroshi, Sobajima, Hisanori, Ishiguro, Rika, Sato, Hiroyuki, Totsu, Satsuki, Ishii, Nozomi, Hosono, Shigeharu, Shiraishi, Mika, Miura, Humihiro, Nakao, Atsushi, Yoda, Hitoshi, Shimizu, Mitsumasa, Seki, Kazuo, Itani, Yasuhumi, Suzuki, Keiji, Nemoto, Atsushi, Nakamura, Tomohiko, Wada, Masaki, Nagayama, Yoshihisa, Numata, Osamu, Futatani, Takeshi, Ueno, Yasuhisa, Iwai, Kazuyuki, Kono, Yoshinori, Ooki, Shigeru, Nakazawa, Yusuke, Suzuki, Chizuko, Tanaka, Taihei, Bonno, Motoki, Nakamura, Kenji, Kihara, Minako, Sano, Hiroyuki, Shiraishi, Atsushi, Ohashi, Atsushi, Ichiba, Hiroyuki, Sumi, Kiyoaki, Yoshimoto, Seiji, Takahashi, Yukihiro, Okutani, Takahiro, Miura, Masumi, Kato, Fumihide, Watabe, Shinichi, Kageyama, Misao, Fukuhara, Rie, Hayashitani, Michiko, Hasegawa, Keiko, Koyano, Kosuke, Kobayashi, Shoko, Akiyoshi, Shinosuke, Nakata, Yusei, Kanda, Takeshi, Tadashi, Hisano, Kanda, Hiroshi, Nakamura, Masaki, Matsumoto, Naoko, Ochiai, Masayuki, Aoki, Mikihiro, Kawase, Akihiko, Iida, Koichi, Ishihara, Chie, Kohama, Moriyasu, Seara, M<ce:sup loc='post">a</ce:sup> José Fernández, Bermúdez, José M<ce:sup loc='post">a</ce:sup> Fraga, Martínez Gutiérrez, Andrés, Martínez Ayúcar, María Mercedes, Díaz, Carolina Vizcaíno, Quiles Durá, José Luis, González Santacruz, María, Siguile, M<ce:sup loc='post">a</ce:sup> Anne Feret, Fernández, Adela Rodríguez, Fernández Colomer, Belén, García López, Enrique, Figuera Aloy, Josep, Botet Mussons, Francesc, Anquela Sanz, Israel, Galiana, Gemma Ginovart, Moliner Calderon, Elisenda, Pujol, Antonio Natal, Vives, Alicia Mirada, Iriondo Sanz, Martín, Porta, Roser, Cogul, Eva Capdevila, Castells Vilella, Laura, Álvarez, Bruno Alonso, Montero Macarro, José María, Barrio Sacristán, Ana R., Cuesta, M<ce:sup loc='post">a</ce:sup> Jesús López, Tardío, Ortiz, Sánchez Puerta, Eugenia Valls, Benavente Fernández, Isabel, Romero, Juan Mena, Martinez Gimenez, María Dolores, Olmos, Ramón Aguilera, Segura, Ricardo Tosca, Cabañas, Juana M<ce:sup loc='post">a</ce:sup> Guzmán, Muñoz, M<ce:sup loc='post">a</ce:sup> Dolores Huertas, Trujillo, Alberto, Moltó Ripoll, Luis Fidel, Hurtado Suazo, José Antonio, Aldea Romero, Ana Elena, Grisolía, Luis Paisán, Garrido Ocana, Ana Isabel, Soblechero, Eduardo Garcia, Ruiz del Prado, M<ce:sup loc='post">a</ce:sup> Yolanda, Díez, Inés Esteba, González-Luis, Gema E., García-Muñoz Rodrigo, Fermín, Iglesias, Emilio Álvaro, Calvo, Fernando Fernandez, Solé Mir, Eduard, Martí, Jordi Garcia, Ortiz Movilla, Roberto, Vilaplana, Lucía Cabanillas, San Miguel, Marta García, Martín, Isabel Llana, Díaz, María Fernández, Pérez Rodríguez, Jesús, Salas, Sofía, Labian, Carmen Muñoz, González Armengod, Carmen, Comeche, Laura Domingo, Sánchez Tamayo, Tomás, García del Río, Manuel, Alonso Gallego, José Ángel, Lloreda Garcia, José María, González, Javier Vilas, Ocampo, Insunza, Nieves Balado, García González, Pilar, Granero Asencio, Mercedes, Sanz, Antonia López, Díaz, Carmen Macías, Ferrari Cortés, Araceli, Fuster Jorge, Pedro Amadeo, López Mendoza, Santiago, Ramírez, Sabina Romero, Font, M<ce:sup loc='post">a</ce:sup> del Mar Albújar, de Ureta Huertas, Alicia, Plana, Antonio Arroyos, Capell, Javier Estañ, Roqués, Vicente, Morcillo, F., Marín, Sara, Omaña, María Fernanda, Iturriaga, Gabriel Saitua, Kofron, Jiri, Brodd, Katarina Strand, Odlind, Andreas, Alberg, Lars, Arwehed, Sofia, Engström, Eva, Kasemo, Anna, Ekelund, Charlotte, Åhman, Lars, Ingemarsson, Fredrik, Österdahl, Laura, Thurn, Pernilla, Albinsson, Eva, Selander, Bo, Lundberg, Fredrik, Heimdahl, Ingela, Hafström, Ola, Wejryd, Erik, Kuusima-Löfbom, Johanna, Lund, Ellen-Elisabeth, Thorén, Annelie, Hallberg, Boubou, Broström, Eva Berggren, Hertzberg, Torbjörn, Stjernstedt, Björn, Robinson, Johan, Farooqi, Aijaz, Normann, Erik, Fredriksson, Magnus, Palm, Anders, Hedblom, Åsa, Sjöberg, Kenneth, Thorbjörnsson, Leif, Ohlin, Andreas, Florell, Rein, Smedsaas-Löfvenberg, Agneta, Meyer, Philipp, Anderegg, Claudia, Schulzke, Sven, Nelle, Mathias, Wagner, Bendicht, Bär, Walter, Kaczala, Grégoire, Pfister, Riccardo E., Tolsa, Jean-François, Roth, Matthias, Berger, Thomas M., Laubscher, Bernhard, Malzacher, Andreas, Micallef, John P., Hegi, Lukas, Bassler, Dirk, Arlettaz, Romaine, Bernet, Vera, Bag, Santanu, Kefas, Jonathan, Rackham, Oliver, Thirumurgan, Arumugavelu, Yoxall, Bill, McBride, Tim, Webb, Delyth, Amegavie, Laweh, Hassan, Ahmed, Ambadkar, Priyadarshan, Dyke, Mark, Babiker, Seif, Rubin, Susan, Ogilvy-Stuart, Amanda, Panasa, Nagesh, Settle, Paul, Moise, Jonathan, Edi-Osagie, Ngozi, Heal, Carrie, Birch, Jacqeline, Hasib, Abdul, Soe, Aung, Kumar, Niraj, Kisat, Hamudi, Vasu, Vimal, Lama, Meera, Gupta, Richa, Rawlingson, Chris, Wickham, Tim, Schwarz, Karin, Sommen, Van, Watkin, Sara, Gupta, Aashish, Aladangady, Narendra, Ali, Imdad, Alsford, Lesley, Mannan, Khalid, Rainer, Ebel, Wilson, Nicholas, Thomas, Mark, Mathur, Ramnik, Cruwys, Michele, Godambe, Sunit, Watts, Timothy, Kuna, Jauro, Chang, John, Filkin, Jon, Huddy, Charlotte, Shephard, Ruth, Zieba, Krzystof, Rao, Patti, Currie, Andrew, Manzoor, Azhar, Ahmed, Munir, Simmons, Phil, Nycyk, Julie, Gallagher, Andrew, Halahakoon, Chrisantha, Deshpande, Sanjeev, Mohite, Anand, Palmer, Kate, Gibson, Alan, Garbash, Mehdi, Lal, Mithilesh, Abu-Harb, Majd, McKeon-Carter, Róisín, Selter, Michael, Munyard, Paul, Lewis, Vaughan, Raman, Mala, Whincup, Graham, Mallik, Abdus, Amess, Philip, Godden, Charles, Reynolds, Peter, Misra, Indranil, Shettihalli, Naveen, De Halpert, Peter, Salgia, Sanjay, Sanghavi, Rekha, Wigfield, Ruth, Deketelaere, Abby, Khashu, Minesh, Hall, Michael, Groves, Charlotte, Brown, Nick, Brennan, Nick, Vamvakiti, Katia, Ratnayaka, Mal, Pirie, Simon, Jones, Stephen, Mannix, Paul, Harding, David, Eaton, Megan, Gibson, David, Miall, Lawrence, Shah, Prakesh S., Sjörs, Gunnar, Mirea, Lucia, Reichman, Brian, Adams, Mark, Modi, Neena, Darlow, Brian A., Kusuda, Satoshi, San Feliciano, Laura, Yang, Junmin, Håkansson, Stellan, Mori, Rintaro, Figueras-Aloy, Josep, and Lee, Shoo K.

Published
2016
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19. Need for standardized vancomycin dosing for coagulase-negative staphylococci in hospitalized infants

Author

Harvey, Eleanor J., primary, Ashiru-Oredope, Diane, additional, Hill, Louise F., additional, Demirjian, Alicia, additional, Paranthaman, Karthik, additional, Jauneikaite, Elita, additional, Wan, Yu, additional, Hope, Russell, additional, Robb, Andrew, additional, Thorn, Louise, additional, Fleming, Paul, additional, Pichon, Bruno, additional, Ready, Derren, additional, Elsayed, Mustafa, additional, Felgate, Heather, additional, Moore, Ginny, additional, Pattnayak, Santosh, additional, Ali, Sakina, additional, Gasiorowski, Ted, additional, Watts, Timothy, additional, Wooster, Louise, additional, Payne, Vicky, additional, Brown, Colin, additional, Claxton, Alleyna, additional, Kortsalioudaki, Christina, additional, Patel, Mitul, additional, Mughal, Nabeela, additional, Moncayo, Olga, additional, Banerjee, Sujoy, additional, McKechnie, Liz, additional, Gandhi, Rashmi, additional, DCosta, Rhys, additional, Khashu, Minesh, additional, Ratnaraja, Natasha, additional, Sethi, Kavita, additional, Drysdale, Simon, additional, and Patel, Bharat, additional

Published
2023
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20. Need for standardized vancomycin dosing for coagulase-negative staphylococci in hospitalized infants

Author

Paranthaman, Karthik, Jauneikaite, Elita, Wan, Yu, Hope, Russell, Robb, Andrew, Thorn, Louise, Fleming, Paul, Pichon, Bruno, Ready, Derren, Elsayed, Mustafa, Felgate, Heather, Moore, Ginny, Pattnayak, Santosh, Ali, Sakina, Gasiorowski, Ted, Watts, Timothy, Wooster, Louise, Payne, Vicky, Brown, Colin, Claxton, Alleyna, Kortsalioudaki, Christina, Patel, Mitul, Mughal, Nabeela, Moncayo, Olga, Banerjee, Sujoy, McKechnie, Liz, Gandhi, Rashmi, DCosta, Rhys, Khashu, Minesh, Ratnaraja, Natasha, Sethi, Kavita, Drysdale, Simon, Patel, Bharat, Harvey, Eleanor J., Ashiru-Oredope, Diane, Hill, Louise F., and Demirjian, Alicia

Published
2023
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22. COVID-19 restrictions and psychological well-being of fathers with infants admitted to NICU—An exploratory cross-sectional study

Author

Adama, Esther Abena, Koliouli, Flora, Provenzi, Livio, Feeley, Nancy, van Teijlingen, Edwin, Ireland, Jillian, Thomson-Salo, Frances, Khashu, Minesh, Adama, Esther Abena, Koliouli, Flora, Provenzi, Livio, Feeley, Nancy, van Teijlingen, Edwin, Ireland, Jillian, Thomson-Salo, Frances, and Khashu, Minesh

Abstract

Aim: To describe the impact of the COVID-19 restrictions on the caregiving activities and psychological well-being of fathers with infants admitted to neonatal units. Methods: Cross-sectional study using adapted COPE-IS and COPE-IU tools. Participants' recruitment occurred online via social media and parents' associations. Online survey in English, French and Italian were distributed and promoted via websites and social media platforms of parent's associations. The study was undertaken across 12 countries in Asia, Australia, Africa and Europe. Results: A total of 108 fathers of NICU infants completed the survey. COVID-19 related restrictions were categorised into 3 types: no restrictions, partial and severe restrictions. Fathers who experienced partial restrictions reported more involvement in caregiving activities but high levels of emotional difficulties and sleeping problems compared to those who experienced full or no restrictions. Conclusion: Given the impact on the psychological well-being of fathers, restrictions should be avoided as much as possible in the neonatal unit and fathers given free access to their infants if they follow appropriate infection control precautions.

Published
2022

23. Current Understanding of Transfusion-associated Necrotizing Enterocolitis: Review of Clinical and Experimental Studies and a Call for More Definitive Evidence

Author

Kumar, Praveen, primary, Garg, Parvesh M, additional, De Plaen, Isabelle G, additional, Christensen, Robert D, additional, Khashu, Minesh, additional, Dame, Christof, additional, Lavoie, Pascal M, additional, Sampath, Venkatesh, additional, Malhotra, Atul, additional, Caplan, Michael D, additional, Agrawal, Pankaj B, additional, Buonocore, Giuseppe, additional, and Maheshwari, Akhil, additional

Published
2022
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24. Information Overload.

Author

Khashu, Minesh

Subjects
*HEALTH, *INFORMATION resources, *DECISION making, *INFORMATION overload
Abstract

A personal narrative is presented in which the author explores the issue of information overload, its impact on decision-making, and the newly coined term "comparison overload" affecting mental well-being.

Published
2024

28. COVID-19 restrictions and fathers of infants in neonatal care

Author

Khashu, Minesh, Provenzi, L., Adama, E., Garfield, C., Koliouli, F., Fisher, D., Nørgaard, B., Thomson-Salo, F., van Teijlingen, Edwin, Ireland, Jillian, and Feeley, N.

Abstract

This is a letter without an abstract.

Published
2020

29. Persistent bacteremia and severe thrombocytopenia caused by coagulase-negative Staphylococcus in a neonatal intensive care unit

Author

Khashu, Minesh, Osiovich, Horacio, Henry, Deborah, Khotani, Aziz Al, Solimano, Alfonso, and Speert, David P.

Subjects
Bacteremia -- Risk factors, Sepsis -- Causes of, Staphylococcus -- Risk factors
Abstract

OBJECTIVE. Coagulase-negative Staphylococcus (CONS) is the most frequent cause of late-onset sepsis in NICUs, but mortality is rare and morbidity is unusual. We report a new syndrome of CoNS sepsis characterized by significant morbidity and persistent bacteremia despite aggressive antibiotic therapy and no identified focus of infection. METHODS. We conducted a retrospective review of infants in the NICU with CoNS bacteremia between 2000 and 2002. Statistical analysis included an initial exploratory analysis followed by logistic regression. Microbiological identification of all isolates and molecular typing were performed. RESULTS. Thirty-one neonates with persistent CoNS bacteremia were compared with 60 randomly selected neonates from a group of 140 with nonpersistent CoNS bacteremia. The clinical manifestations at presentation, gestational ages, and birth weights were similar in the 2 groups. Thrombocytopenia was present in 26 (84%) neonates with persistent CoNS bacteremia but only in 8 (13%) neonates in the nonpersistent group. Central venous catheterization increased the risk for persistent CoNS bacteremia, but 42% of the persistent group was never catheterized. Staphylococcus epidermidis was the most common isolate in both groups. Molecular typing failed to identify a predominant clone. CONCLUSIONS. The syndrome of persistent CoNS septicemia is remarkable for thrombocytopenia and persistence in the absence of central venous catheterization. Clinical manifestations at presentation and demographic characteristics did not discriminate between the persistent and nonpersistent groups. We did not identify the emergence of a particularly virulent clone, but it is possible that some strains of CoNS have acquired the capacity to persist under different conditions. Key Words neonatal sepsis, Staphylococcus epidermidis, DNA fingerprinting Abbreviations CONS--coagulase-negative Staphylococcus VLBW--very low birth weight PN--parenteral nutrition WCC--white cell count PFGE--pulsed-field gel electrophoresis RAPD--random amplified polymorphic DNA, COAGULASE-NEGATIVE STAPHYLOCOCCUS (CONS) is the most frequent cause of late-onset sepsis in NICUs. (1-4) Most studies have shown that infections with CoNS are not associated with significant mortality or morbidity. [...]

Published
2006

33. Necrotizing Enterocolitis: Using Regulatory Science and Drug Development to Improve Outcomes

Author

Allen, Marilee, Baer, Gerri, Besner, Gail, Canvasser, Jennifer, Chaaban, Hala, Clay, Robert, Connolly, Eamonn, Davis, Jonathan M., Duchon, Jennifer, Eklund, Wakako, Ferguson, Joanne, Good, Misty, Grogan, Cristal, Hudson, Lynn, Khashu, Minesh, Kim, Jae, Lotze, Andrea, Mangili, Alexandra, Markel, Troy, Martin, Laura, Miyazawa, Tokuo, Neu, Josef, Noel, Gary, Portman, Ron, Rosito, Simone, Schwartz, Ann, Scottoline, Brian, Seo, Suna, Stromberg, Staffan, Treem, William, Umberger, Erin, Warren, Tracy, West, Alicia, Caplan, Michael S., Underwood, Mark A., Modi, Neena, Patel, Ravi, Gordon, Phillip V., Sylvester, Karl G., McElroy, Steven, Manzoni, Paolo, Gephart, Sheila, Chwals, Walter J., and Turner, Mark A.

Published
2019
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44. Necrotizing Enterocolitis: Using Regulatory Science and Drug Development to Improve Outcomes

Author

Caplan, Michael S., primary, Underwood, Mark A., additional, Modi, Neena, additional, Patel, Ravi, additional, Gordon, Phillip V., additional, Sylvester, Karl G., additional, McElroy, Steven, additional, Manzoni, Paolo, additional, Gephart, Sheila, additional, Chwals, Walter J., additional, Turner, Mark A., additional, Davis, Jonathan M., additional, Allen, Marilee, additional, Baer, Gerri, additional, Besner, Gail, additional, Canvasser, Jennifer, additional, Chaaban, Hala, additional, Clay, Robert, additional, Connolly, Eamonn, additional, Duchon, Jennifer, additional, Eklund, Wakako, additional, Ferguson, Joanne, additional, Good, Misty, additional, Grogan, Cristal, additional, Hudson, Lynn, additional, Khashu, Minesh, additional, Kim, Jae, additional, Lotze, Andrea, additional, Mangili, Alexandra, additional, Markel, Troy, additional, Martin, Laura, additional, Miyazawa, Tokuo, additional, Neu, Josef, additional, Noel, Gary, additional, Portman, Ron, additional, Rosito, Simone, additional, Schwartz, Ann, additional, Scottoline, Brian, additional, Seo, Suna, additional, Stromberg, Staffan, additional, Treem, William, additional, Umberger, Erin, additional, Warren, Tracy, additional, and West, Alicia, additional

Published
2019
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46. Fathers in neonatal units: Improving infant health by supporting the baby-father bond and mother-father coparenting

Author

Fisher, Duncan, primary, Khashu, Minesh, additional, Adama, Esther A., additional, Feeley, Nancy, additional, Garfield, Craig F., additional, Ireland, Jillian, additional, Koliouli, Flora, additional, Lindberg, Birgitta, additional, Nørgaard, Betty, additional, Provenzi, Livio, additional, Thomson-Salo, Frances, additional, and van Teijlingen, Edwin, additional

Published
2018
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47. Implementation of bowel ultrasound practice for the diagnosis and management of necrotising enterocolitis.

Author

Alexander, Karen M., Chan, Sherwin S., Opfer, Erin, Cuna, Alain, Fraser, Jason D., Sharif, Shazia, and Khashu, Minesh

Subjects
ENTEROCOLITIS, NEONATAL necrotizing enterocolitis, INTESTINAL intussusception, HEPATIC portal system, INFLAMMATORY bowel diseases, PROGNOSIS, GASTROINTESTINAL diseases
Abstract

Necrotising enterocolitis (NEC) is a serious inflammatory bowel disease of prematurity with potentially devastating complications and remains a leading cause of morbidity and mortality among premature infants. In recent years, there has been accumulating data regarding benefits of using bowel ultrasound (BUS) in the diagnosis and management of NEC. Despite this, adoption of robust BUS programmes into clinical practice has been slow. As BUS is a relatively new technique, many barriers to implementation exist, namely lack of education and training for sonographers and radiologists, low case volume and unfamiliarity by clinicians regarding how to use the information provided. The aim of this manuscript is to provide a framework and a roadmap for units to implement BUS in day-to-day practice for NEC diagnosis and management. [ABSTRACT FROM AUTHOR]

Published
2021
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49. 15 Trees to Negate the CO2 Effect of Living #15treesformylife.

Author

Khashu, Minesh

Subjects
*POLLUTION prevention, *CONSERVATION of natural resources, *PLANTS, *ENVIRONMENTAL health, *CARBON dioxide, *GREENHOUSE effect, *CLIMATE change, *HEALTH promotion
Abstract

The article emphasizes the need to address the CO2 emissions generated by human existence by planting 15 trees per person to counteract the environmental impact. Topics include the importance of acknowledging individual carbon footprints, promoting sustainability, and taking actionable steps to mitigate environmental harm through tree planting initiatives.

Published
2024

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