20 results on '"Khandoga, Alexander G."'
Search Results
2. Contributors
- Author
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Abdel-Wahab, Omar, primary, Abrahm, Janet L., additional, Adams, Sharon, additional, Adewoye, Adeboye H., additional, Allen, Carl, additional, Ambinder, Richard F., additional, Anasetti, Claudio, additional, Anastasi, John, additional, Anderson, Julia A., additional, Antin, Joseph H., additional, Antony, Aśok C., additional, Araten, David J., additional, Armand, Philippe, additional, Armstrong, Gillian, additional, Armstrong, Scott A., additional, Arnold, Donald M., additional, Artz, Andrew S., additional, Awan, Farrukh T., additional, Baglin, Trevor P., additional, Benson, Don M., additional, Benz, Edward J., additional, Berliner, Nancy, additional, Bhagat, Govind, additional, Bhardwaj, Nina, additional, Bhatia, Ravi, additional, Bhatia, Smita, additional, Bhatt, Mihir D., additional, Bhatt, Vijaya Raj, additional, Bitan, Menachem, additional, Blinderman, Craig D., additional, Bollard, Catherine M., additional, Braun, Benjamin S., additional, Brenner, Malcolm K., additional, Brittenham, Gary M., additional, Brodsky, Robert A., additional, Brown, Myles, additional, Broxmeyer, Hal E., additional, Brummel-Ziedins, Kathleen, additional, Brunner, Andrew M., additional, Buadi, Francis K., additional, Burkhardt, Birgit, additional, Burns, Melissa, additional, Byrd, John C., additional, Caimi, Paolo F., additional, Caligiuri, Michael A., additional, Canavan, Michelle, additional, Cantor, Alan B., additional, Carcao, Manuel, additional, Carroll, Michael C., additional, Carty, Shannon A., additional, Castillo, Jorge J., additional, Chan, Anthony K.C., additional, Chapin, John, additional, Chiu, April, additional, Chute, John P., additional, Clark, David B., additional, Coates, Thomas D., additional, Cogle, Christopher R., additional, Connell, Nathan T., additional, Cooke, Elizabeth, additional, Cooley, Sarah, additional, Corradini, Paolo, additional, Creager, Mark A., additional, Creger, Richard J., additional, Cromwell, Caroline, additional, Crowther, Mark A., additional, Cushing, Melissa M., additional, Cutler, Corey, additional, Dang, Chi V., additional, Danial, Nika N., additional, Dave, Sandeep S., additional, DeCaprio, James A., additional, Dinauer, Mary C., additional, Dinner, Shira, additional, Diz-Küçükkaya, Reyhan, additional, Dodd, Roger Y., additional, Donato, Michele L., additional, Dorshkind, Kenneth, additional, Dotti, Gianpietro, additional, Dror, Yigal, additional, Dunleavy, Kieron, additional, Dvorak, Christopher C., additional, Ebert, Benjamin L., additional, Eck, Michael J., additional, Eikelboom, John W., additional, Epperla, Narendranath, additional, Ershler, William B., additional, Evans, William E., additional, Faderl, Stefan, additional, Ferrara, James L.M., additional, Filipovich, Alexandra Hult, additional, Fischer, Martin, additional, Fredenburgh, James C., additional, Friedman, Kenneth D., additional, Fuchs, Ephraim, additional, Fuller, Stephen J., additional, Gailani, David, additional, Galipeau, Jacques, additional, Gallagher, Patrick G., additional, Ganapathi, Karthik A., additional, Gardner, Lawrence B., additional, Gee, Adrian P., additional, Gerson, Stanton L., additional, Gertz, Morie A., additional, Giardina, Patricia J., additional, Gibson, Christopher J., additional, Golan, Karin, additional, Golub, Todd R., additional, Gonzales, Matthew J., additional, Gotlib, Jason, additional, Gottschalk, Stephen, additional, Grant, Marianne A., additional, Graubert, Timothy A., additional, Gregg, Xylina T., additional, Gribben, John G., additional, Gross, Dawn M., additional, Gruber, Tanja A., additional, Guitart, Joan, additional, Gurbuxani, Sandeep, additional, Gur-Cohen, Shiri, additional, Gutierrez, Alejandro, additional, Hamadani, Mehdi, additional, Hari, Parameswaran N., additional, Hartwig, John H., additional, Hayman, Suzanne R., additional, Hayward, Catherine P.M., additional, Hebbel, Robert P., additional, Heslop, Helen E., additional, Hillis, Christopher, additional, Hillyer, Christopher D., additional, Ho, Karin, additional, Hockenbery, David M., additional, Hoffman, Ronald, additional, Hogg, Kerstin E., additional, Holtan, Shernan G., additional, Horny, Hans-Peter, additional, Hsu, Yen-Michael S., additional, Hunter, Zachary R., additional, Huntington, James A., additional, Iancu-Rubin, Camelia, additional, Iqbal, Ali, additional, Isenman, David E., additional, Israels, Sara J., additional, Italiano, Joseph E., additional, Jaffe, Elaine S., additional, Jaffer, Iqbal H., additional, Jagannath, Sundar, additional, Jäger, Ulrich, additional, Jain, Nitin, additional, James, Paula, additional, Jeha, Sima, additional, Jordan, Michael B., additional, Josephson, Cassandra D., additional, Jung, Moonjung, additional, Kager, Leo, additional, Kambayashi, Taku, additional, Kanakry, Jennifer A., additional, Kantarjian, Hagop M., additional, Kaplan, Jason, additional, Karafin, Matthew S., additional, Karsan, Aly, additional, Kaufman, Randal J., additional, Kaufman, Richard M., additional, Keller, Frank G., additional, Kelly, Kara M., additional, Kessler, Craig M., additional, Key, Nigel S., additional, Keyzner, Alla, additional, Khandoga, Alexander G., additional, Khanna-Gupta, Arati, additional, Khatib-Massalha, Eman, additional, Klein, Harvey G., additional, Knoechel, Birgit, additional, Kollet, Orit, additional, Konkle, Barbara A., additional, Kontoyiannis, Dimitrios P., additional, Koreth, John, additional, Koretzky, Gary A., additional, Kotecha, Dipak, additional, Kremyanskaya, Marina, additional, Kumari, Anju, additional, Kuzel, Timothy M., additional, Küppers, Ralf, additional, Lacy, Martha Q., additional, Ladas, Elana, additional, Landier, Wendy, additional, Lapid, Kfir, additional, Lapidot, Tsvee, additional, Larson, Peter J., additional, Levi, Marcel, additional, Lewis, Russell E., additional, Liebman, Howard A., additional, Lillicrap, David, additional, Lim, Wendy, additional, Lin, Judith C., additional, Lindblad, Robert, additional, Lip, Gregory Y.H., additional, Little, Jane A., additional, Lohr, Jens G., additional, López, José A., additional, Luscinskas, Francis W., additional, Maciejewski, Jaroslaw P., additional, Majhail, Navneet S., additional, Manches, Olivier, additional, Mandle, Robert J., additional, Mann, Kenneth G., additional, Manno, Catherine S., additional, Marcogliese, Andrea N., additional, Mariani, Guglielmo, additional, Marincola, Francesco M., additional, Mascarenhas, John, additional, Massberg, Steffen, additional, McEver, Rodger P., additional, McGrath, Emer, additional, McKinney, Matthew S., additional, Mehta, Rohtesh S., additional, Mentzer, William C., additional, Merlini, Giampaolo, additional, Merryman, Reid, additional, Michel, Marc, additional, Migliaccio, Anna Rita, additional, Miller, Jeffrey S., additional, Mims, Martha P., additional, Mondoro, Traci Heath, additional, Moorehead, Paul, additional, Muniz, Luciana R., additional, Munshi, Nikhil C., additional, Najfeld, Vesna, additional, Nayak, Lalitha, additional, Nazy, Ishac, additional, Neff, Anne T., additional, Ness, Paul M., additional, Notarangelo, Luigi D., additional, O'Brien, Sarah H., additional, O'Connor, Owen A., additional, O'Donnell, Martin, additional, Olson, Amanda, additional, Orkin, Stuart H., additional, Pai, Menaka, additional, Pai, Sung-Yun, additional, Paidas, Michael, additional, Panch, Sandhya R., additional, Pande, Reena L., additional, Papayannopoulou, Thalia, additional, Parikh, Rahul, additional, Petersdorf, Effie W., additional, Peterson, Shane E., additional, Pittaluga, Stefania, additional, Ponce, Doris M., additional, Popolo, Laura, additional, Prchal, Josef T., additional, Pui, Ching-Hon, additional, Puigserver, Pere, additional, Rak, Janusz, additional, Ramos, Carlos A., additional, Rand, Jacob H., additional, Rand, Margaret L., additional, Rao, Dinesh S., additional, Ravandi, Farhad, additional, Rawlings, David J., additional, Reddy, Pavan, additional, Reding, Mark T., additional, Reiter, Andreas, additional, Rice, Lawrence, additional, Riese, Matthew J., additional, Ritchey, Arthur Kim, additional, Roberts, David J., additional, Roman, Elizabeth, additional, Rooney, Cliona M., additional, Rosen, Steven T., additional, Rosenthal, David S., additional, Rossmann, Marlies P., additional, Rot, Antal, additional, Rowley, Scott D., additional, Rubnitz, Jeffrey E., additional, Rydz, Natalia, additional, Salama, Mohamed E., additional, Sauk, Steven, additional, Saunthararajah, Yogen, additional, Savage, William, additional, Scadden, David, additional, Schaefer, Kristen G., additional, Schiffman, Fred, additional, Schneidewend, Robert, additional, Schrier, Stanley L., additional, Schuchman, Edward H., additional, Scullion, Bridget Fowler, additional, Selvaggi, Kathy J., additional, Senoo, Keitaro, additional, Shaheen, Montaser, additional, Shaz, Beth H., additional, Shelburne, Samuel A., additional, Shpall, Elizabeth J., additional, Shurin, Susan B., additional, Siegal, Deborah, additional, Silberstein, Leslie E., additional, Silberstein, Lev, additional, Silverstein, Roy L., additional, Sloan, Steven R., additional, Smith, Franklin O., additional, Smith, James W., additional, Smith, Katy, additional, Steensma, David P., additional, Steinberg, Martin H., additional, Stock, Wendy, additional, Storry, Jill R., additional, Stramer, Susan L., additional, Strauss, Ronald G., additional, Stroncek, David F., additional, Taylor, Justin, additional, Thota, Swapna, additional, Treon, Steven P., additional, Tulpule, Anil, additional, Valdes, Roberto Ferro, additional, Valent, Peter, additional, Vedantham, Suresh, additional, Vercellotti, Gregory M., additional, Verneris, Michael R., additional, Vichinsky, Elliott P., additional, von Andrian, Ulrich H., additional, Vose, Julie M., additional, Wagner, Andrew J., additional, Wang, Ena, additional, Wang, Jia-huai, additional, Warkentin, Theodore E., additional, Wasserstein, Melissa P., additional, Webster, Ann, additional, Weisdorf, Daniel J., additional, Weitz, Jeffrey I., additional, Westhoff, Connie M., additional, Wheeler, Allison P., additional, Widick, Page, additional, Wiley, James S., additional, William, Basem M., additional, Williams, David A., additional, Wilson, Wyndham H., additional, Wolfe, Joanne, additional, Wolgast, Lucia R., additional, Wood, Deborah, additional, Wu, Jennifer, additional, Yahalom, Joachim, additional, Yee, Donald L., additional, Younes, Anas, additional, Young, Neal S., additional, and Zeller, Michelle P., additional
- Published
- 2018
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3. Chemokines and Hematopoietic Cell Trafficking
- Author
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Rot, Antal, primary, Massberg, Steffen, additional, Khandoga, Alexander G., additional, and von Andrian, Ulrich H., additional
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- 2018
- Full Text
- View/download PDF
4. Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue
- Author
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Lerchenberger, Max, Uhl, Bernd, Stark, Konstantin, Zuchtriegel, Gabriele, Eckart, Annekathrin, Miller, Meike, Puhr-Westerheide, Daniel, Praetner, Marc, Rehberg, Markus, Khandoga, Alexander G., Lauber, Kirsten, Massberg, Steffen, Krombach, Fritz, and Reichel, Christoph A.
- Published
- 2013
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5. von Willebrand factor promotes leukocyte extravasation
- Author
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Petri, Björn, Broermann, Andre, Li, Hang, Khandoga, Alexander G., Zarbock, Alexander, Krombach, Fritz, Goerge, Tobias, Schneider, Stefan W., Jones, Claire, Nieswandt, Bernhard, Wild, Martin K., and Vestweber, Dietmar
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- 2010
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6. CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis
- Author
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Bixel, M. Gabriele, Li, Hang, Petri, Bjoern, Khandoga, Alexander G., Khandoga, Andrej, Zarbock, Alexander, Wolburg-Buchholz, Karen, Wolburg, Hartwig, Sorokin, Lydia, Zeuschner, Dagmar, Maerz, Sigrid, Butz, Stefan, Krombach, Fritz, and Vestweber, Dietmar
- Published
- 2010
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7. Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation
- Author
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Schulz, Christian, Leuschen, Nina V., Fröhlich, Thomas, Lorenz, Michael, Pfeiler, Susanne, Gleissner, Christian A., Kremmer, Elisabeth, Kessler, Mirjam, Khandoga, Alexander G., Engelmann, Bernd, Ley, Klaus, Massberg, Steffen, and Arnold, Georg J.
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- 2010
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8. Leukocyte transmigration in inflamed liver: A role for endothelial cell-selective adhesion molecule
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Khandoga, Andrej, Huettinger, Stefanie, Khandoga, Alexander G., Li, Hang, Butz, Stefan, Jauch, Karl-Walter, Vestweber, Dietmar, and Krombach, Fritz
- Published
- 2009
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9. A CD99-related antigen on endothelial cells mediates neutrophil but not lymphocyte extravasation in vivo
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Bixel, M. Gabriele, Petri, Björn, Khandoga, Alexander G., Khandoga, Andrej, Wolburg-Buchholz, Karen, Wolburg, Hartwig, März, Sigrid, Krombach, Fritz, and Vestweber, Dietmar
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- 2007
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10. The Role of Interstitial Macrophages in Nephropathy of Type 2 Diabetic db/db Mice
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Ninichuk, Volha, Khandoga, Alexander G., Segerer, Stephan, Loetscher, Pius, Schlapbach, Achim, Revesz, Laszlo, Feifel, Roland, Khandoga, Andrej, Krombach, Fritz, Nelson, Peter J., Schlöndorff, Detlef, and Anders, Hans-Joachim
- Published
- 2007
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11. Contributors
- Author
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Abdel-Wahab, Omar, Abrahm, Janet L., Abutalib, Syed A., Adams, Sharon, Al Hadidi, Samer, Alcaide, Pilar, Allen, Carl E., Ambinder, Richard F., Amonoo, Hermioni L., Anderson, Julia A.M., Antin, Joseph H., Antony, Aśok C., Araten, David J., Arnold, Donald M., Awan, Farrukh T., Ayers, Emily C., Barth, Peter, Bates, Shannon M., Benz, Edward J., Berliner, Nancy, Bhardwaj, Nina, Bhatia, Smita, Bhatt, Mihir D., Bollard, Catherine M., Bowman, Mackenzie, Boyle, Eileen M., Braun, Benjamin S., Brenner, Malcolm K., Broccoli, Alessandro, Brodsky, Robert A., Brown, Myles, Broxmeyer, Hal E., Brummel-Ziedins, Kathleen, Brunner, Andrew M., Brunstein, Claudio G., Buadi, Francis K., Burkhardt, Birgit, Burns, Melissa A., Bussel, James B., Byrd, John C., Caimi, Paolo F., Camaschella, Clara, Canavan, Michelle, Cantor, Alan B., Capitano, Maegan L., Carcao, Manuel, Carrillo-Farga, Joaquin, Carroll, Michael C., Carson, William E., Carty, Shannon A., Castillo, Jorge J., Chakrabarti, Priyasmita, Chan, Anthony K.C., Chan, Noel C., Chhabra, Saurabh, Chute, John P., Cimen Bozkus, Cansu, Ciurea, Stefan O., Coates, Thomas D., Collins, Graham, Creager, Mark A., Cromwell, Caroline, Crowder, Lauren A., Cushing, Melissa M., Cutler, Corey, Dabaja, Bouthaina, Dave, Sandeep S., De, Caprio, James A., De, Carli, Kathryn, Deininger, Michael W., De, Simone, Robert A., Dinauer, Mary C., Dinner, Shira, Dixit, Karan S., Dogan, Ahmet, Dorshkind, Kenneth, Dotti, Gianpietro, Dror, Yigal, Dunleavy, Kieron, Dvorak, Christopher C., Ebert, Benjamin L., Eck, Michael J., Eckstein, Olive S., Eikelboom, John W., El Jamal, Siraj M., El-Jurdi, Najla, Kim El-Mallawany, Nader, Erba, Harry P., Evans, William E., Feld, Jonathan, Feldman, Alexander, Ferrara, James L., Fischer, Martin, Forbes, Lisa R., Franco, Idalid, Fredenburgh, James C., Frey, Noelle V., Friedman, Kenneth D., Fuller, Stephen J., Gabe, Caroline, Gailani, David, Gallagher, Patrick G., Gallardo-Grajeda, Andrea, Ganz, Tomas, Gee, Adrian P., George, Gemlyn, Gerson, Stanton L., Gertz, Morie A., Ghosh, Nilanjan, Gibson, Christopher J., Ginzburg, Yelena Z., Gomez, Keith, Gotlib, Jason, Grant, Shakira J., Graubert, Timothy A., Gregg, Xylina T., Gribben, John G., Gross, Peter L., Gulati, Nitya, Gurbuxani, Sandeep, Gutierrez, Alejandro, de Haan, Gerald, Haas-Kogan, Daphne, Haddad, Montaser, Halene, Stephanie, Hamadani, Mehdi, Hammond, Rebecca M., Hari, Parameswaran N., Hayman, Suzanne R., Hayward, Catherine, Hebbel, Robert P., Heidenreich, Olaf, Henkin, Stanislav, Hensch, Lisa, Hillis, Christopher, Hillyer, Christopher D., Hoffman, Ronald, Horny, Hans-Peter, Horowitz, Mia, Hsu, Katharine, Hub, Elin, Iancu-Rubin, Camelia, Isenman, David E., Israels, Sara J., Italiano, Joseph E., Jaffe, Elaine S., Jaffer, Iqbal H., Jäger, Ulrich, Jain, Nitin, James, Paula, Jimenez, Alexandra, Jordan, Michael B., Jung, Moonjung, Kager, Leo, Kanakry, Jennifer A., Kanate, Abraham S., Kelly, Kara M., Khandoga, Alexander G., Karsan, Aly, Kaufman, Richard M., Keyzner, Alla, Khanna-Gupta, Arati, Kharchenko, Evgeniya, Klein, Harvey G., Klepin, Heidi D., Anders Kolb, E., Kollet, Orit, Konopleva, Marina, Kontoyiannis, Dimitrios P., Koreth, John, Koretzky, Gary A., Kozieł-Siołkowska, Monika, Kremyanskaya, Marina, Kucine, Nicole, Kumar, Shaji, Küppers, Ralf, Lacy, Martha Q., Ola Landgren, C., Landier, Wendy, Lane, Andrew A., Lane, William J., Langer, Arielle L., Lapidot, Tsvee, Laureano, Marissa, Leblanc, Francis R., Le, Blanc, Thomas W., La, Casce, Ann S., Lee, Daniel W., Lee, Kathleen A., Leung, Wingchi, Levi, Marcel, Lewis, Russell E., Lichtman, Eben I., Lin, Judith C., Lin, Richard J., Lip, Gregory, Poh Loh, Kah, López, José A., Zoref Lorenz, Adi, Loughran, Thomas P., Lu, Sydney X., Lukas, Rimas V., Lulla, Premal, Luscinskas, Francis W., Ma, Alice D., Maakaron, Joseph E., Machlus, Kellie R., Maciejewski, Jaroslaw P., Magenau, John, Majhail, Navneet, Malek, Ehsan, Manis, John P., Mann, Kenneth G., Manno, Catherine S., Marcellino, Bridget K., Marcogliese, Andrea N., Marincola, Francesco M., Mascarenhas, John, Massberg, Steffen, Matino, Davide, Mc, Ever, Rodger P., Mc, Grath, Emer, Mc, Guire, Hilary, S. Mc, Kinney, Matthew, Mehta, Atul, A. Menapace, Laurel, Mentzer, William C., Michel, Marc, Rita Migliaccio, Anna, Mims, Martha P., Moffat, Karen A., Morgan, Gareth J., Najfeld, Vesna, Naymagon, Leonard, Ness, Paul M., Ng, Andrea K., Ning, Shuoyan, Notarangelo, Luigi D., O'Donnell, Martin, Ollila, Thomas A., Ordonez-Moreno, Alejandra, Own, Maryam, Pai, Menaka, Pai, Sung-Yun, Paidas, Michael, Papa, Luena, Papayannopoulou, Thalia, Peng, Cynthia S., Wang Petersdorf, Effie, Pickard, Lucy, Pierce, Glenn F., Pittaluga, Stefania, Porteus, Matthew, Potpara, Tatjana S., Prchal, Josef T., Puigserver, Pere, Vincent Rajkumar, S., Rak, Janusz, Ramos, Carlos A., Rand, Jacob H., Rand, Margaret L., Rao, Dinesh S., Rappazzo, Katherine C., Rau, Rachel E., Ravandi, Farhad, Rawley, Orla, Rawlings, David J., Reddy, Pavan, Reiter, Andreas, Reville, Barbara, Rice, Lawrence, Riese, Matthew J., Rippel, Noa, Riwes, Mary, Roberts, David J., Rodrigue, Bentley B., Rojek, Alexandra E., Roman, Elizabeth, Rossmann, Marlies P., Rot, Antal, Rouce, Rayne H., Rowley, Scott D., Rustad, Even H., Sahni, Gagan, Sahoo, Daisy, Salama, Mohamed E., Samji, Nasrin, Scadden, David, Schiffman, Fred J., Schipperus, Martin R., Schrier, Stanley L., Shaz, Beth H., Shelburne, Samuel A., Sheth, Sujit, Sholevar, Roxanne, Silberstein, Lev, Silverman, Lewis B., Silverstein, Roy L., Skeith, Leslie, Sloan, Steven R., Douglas Smith, Stephen, Steensma, David P., Steinberg, Martin H., Stieglitz, Elliot, Stock, Wendy, Storry, Jill R., Stramer, Susan L., Strati, Paolo, Stroncek, David F., Flohr Svendsen, Arthur, Sweetenham, John W., Tebaldi, Toma, Teegavarapu, Sravanti P., Tewari, Alok, Lay Thein, Swee, Tillman, Benjamin F., Tomlinson, Benjamin, Tremblay, Douglas, Treon, Steven P., Tsai, Frederick D., Tsang, Mazie, Tzannou, Ifigeneia, Usmani, Saad Z., Valent, Peter, Venkataraman, Girish, Venugopal, Sangeetha, M. Vercellotti, Gregory, Viero, Gabriella, von Andrian, Ulrich H., Vose, Julie M., Wagner, Andrew J., Wang, Ena, Wang, Jia-huai, Warkentin, Theodore E., Weitz, Jeffrey I., West, Kamille A., Westhoff, Connie M., Wheeler, Allison P., Wierda, William, Wiersum-Osselton, Johanna C., Wiley, James S., Williams, David A., Wolgast, Lucia R., Yang, Daozheng, Yang, Moua, Younes, Anas, Young, Neal S., Zayac, Adam S., Zeller, Michelle P., Zieske, Arthur W., Zimran, Ari, Luigi Zinzani, Pier, C. Zubair, Abba, and Michel Zwaan, C.
- Published
- 2023
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- View/download PDF
12. Chapter 12 - Role of Chemokines in Leukocyte Trafficking
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Rot, Antal, Hub, Elin, Massberg, Steffen, Khandoga, Alexander G., and von Andrian, Ulrich H.
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- 2023
- Full Text
- View/download PDF
13. Chapter 13 - Chemokines and Hematopoietic Cell Trafficking
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Rot, Antal, Massberg, Steffen, Khandoga, Alexander G., and von Andrian, Ulrich H.
- Published
- 2018
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14. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies
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Coester Conrad, Reichel Christoph A, Khandoga Alexander G, Praetner Marc, Schultes Stephan, Vippola Minnamari, Bihari Peter, Tuomi Timo, Rehberg Markus, and Krombach Fritz
- Subjects
Toxicology. Poisons ,RA1190-1270 ,Industrial hygiene. Industrial welfare ,HD7260-7780.8 - Abstract
Abstract Background The aim of this study was to establish and validate a practical method to disperse nanoparticles in physiological solutions for biological in vitro and in vivo studies. Results TiO2 (rutile) dispersions were prepared in distilled water, PBS, or RPMI 1640 cell culture medium. Different ultrasound energies, various dispersion stabilizers (human, bovine, and mouse serum albumin, Tween 80, and mouse serum), various concentrations of stabilizers, and different sequences of preparation steps were applied. The size distribution of dispersed nanoparticles was analyzed by dynamic light scattering and zeta potential was measured using phase analysis light scattering. Nanoparticle size was also verified by transmission electron microscopy. A specific ultrasound energy of 4.2 × 105 kJ/m3 was sufficient to disaggregate TiO2 (rutile) nanoparticles, whereas higher energy input did not further improve size reduction. The optimal sequence was first to sonicate the nanoparticles in water, then to add dispersion stabilizers, and finally to add buffered salt solution to the dispersion. The formation of coarse TiO2 (rutile) agglomerates in PBS or RPMI was prevented by addition of 1.5 mg/ml of human, bovine or mouse serum albumin, or mouse serum. The required concentration of albumin to stabilize the nanoparticle dispersion depended on the concentration of the nanoparticles in the dispersion. TiO2 (rutile) particle dispersions at a concentration lower than 0.2 mg/ml could be stabilized by the addition of 1.5 mg/ml albumin. TiO2 (rutile) particle dispersions prepared by this method were stable for up to at least 1 week. This method was suitable for preparing dispersions without coarse agglomerates (average diameter < 290 nm) from nanosized TiO2 (rutile), ZnO, Ag, SiOx, SWNT, MWNT, and diesel SRM2975 particulate matter. Conclusion The optimized dispersion method presented here appears to be effective and practicable for preparing dispersions of nanoparticles in physiological solutions without creating coarse agglomerates.
- Published
- 2008
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15. Chapter 11 - Hematopoietic Cell Trafficking and Chemokines
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Massberg, Steffen, Khandoga, Alexander G., and von Andrian, Ulrich H.
- Published
- 2013
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16. Flavopiridol Protects Against Inflammation by Attenuating Leukocyte-Endothelial Interaction via Inhibition of Cyclin-Dependent Kinase 9
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Schmerwitz, Ulrike K., primary, Sass, Gabriele, additional, Khandoga, Alexander G., additional, Joore, Jos, additional, Mayer, Bettina A., additional, Berberich, Nina, additional, Totzke, Frank, additional, Krombach, Fritz, additional, Tiegs, Gisa, additional, Zahler, Stefan, additional, Vollmar, Angelika M., additional, and Fürst, Robert, additional
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- 2011
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17. Atrial Natriuretic Peptide Protects against Histamine-Induced Endothelial Barrier Dysfunction in Vivo
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Fürst, Robert, primary, Bubik, Martin F., additional, Bihari, Peter, additional, Mayer, Bettina A., additional, Khandoga, Alexander G., additional, Hoffmann, Florian, additional, Rehberg, Markus, additional, Krombach, Fritz, additional, Zahler, Stefan, additional, and Vollmar, Angelika M., additional
- Published
- 2008
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18. Optimized dispersion of nanoparticles for biological in vitro and in vivo studies
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Bihari, Peter, primary, Vippola, Minnamari, additional, Schultes, Stephan, additional, Praetner, Marc, additional, Khandoga, Alexander G, additional, Reichel, Christoph A, additional, Coester, Conrad, additional, Tuomi, Timo, additional, Rehberg, Markus, additional, and Krombach, Fritz, additional
- Published
- 2008
- Full Text
- View/download PDF
19. Contributors
- Author
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Abrahm, Janet L., Abrams, Charles S., Abrams, Donald I., Ackerman, Steven J., Adams, Sharon, Adewoye, Adeboye H., Allen, Carl, Ambinder, Richard F., Anasetti, Claudio, Anastasi, John, Anderson, Julia A., Andreeff, Michael, Antin, Joseph H., Antony, Aśok C., Apostolakis, Stavros, Armstrong, Scott A., Arnold, Donald M., Artz, Andrew S., Awan, Farrukh T., Banchereau, Jacques, Barker, Juliet N., Baum, Linda G., Benson, Don M., Jr., Benz, Edward J., Jr., Berliner, Nancy, Bhagat, Govind, Bhalla, Kapil N., Bhardwaj, Nina, Bhatia, Ravi, Bhatia, Smita, Blinderman, Craig D., Bollard, Catherine M., Brenner, Malcolm K., Brittenham, Gary M., Brodsky, Robert A., Broxmeyer, Hal E., Brummel-Ziedins, Kathleen, Buadi, Francis K., Butterfield, Joseph H., Byrd, John C., Caimi, Paolo F., Caligiuri, Michael A., Campagnaro, Erica, Canaani, Jonathan, Canavan, Michelle, Cantor, Alan B., Carcao, Manuel, Carroll, Michael C., Carty, Shannon A., Champlin, Richard E., Chan, Anthony K.C., Choate, Jacquelyn D., Chung, Peter, Chute, John P., Cines, Douglas B., Clark, David B., Coates, Thomas D., Cogle, Christopher R., Connell, Nathan T., Cooke, Elizabeth, Cooley, Sarah, Corradini, Paolo, Creager, Mark A., Creger, Richard J., Cromwell, Caroline, Cunningham, Regina S., Cushing, Melissa M., Cutler, Corey, Dahl, Gary V., Dang, Chi V., Danial, Nika N., Dave, Sandeep S., DeAngelo, Daniel J., Desai, Madhav V., Dey, Bimalangshu R., Diehl, Volker, Dinauer, Mary C., Diz-Küçükkaya, Reyhan, Donato, Michele L., Dorshkind, Kenneth, Dotti, Gianpietro, Dror, Yigal, Dunleavy, Kieron, Ebert, Benjamin L., Eck, Michael J., Eichenauer, Dennis A., Eikelboom, John W., Engert, Andreas, Ershler, William B., Esmon, Charles T., Esmon, Naomi L., Evans, William E., Faderl, Stefan, Ferrara, James L.M., Filipovich, Alexandra Hult, Freedman, Melvin H., Fuller, Stephen J., Gailani, David, Gallagher, Patrick G., Gardner, Lawrence B., Gee, Adrian P., Gerson, Stanton L., Gertz, Morie A., Giardina, Patricia J., Golan, Karin, Golub, Todd R., Gottschalk, Stephen, Grant, Steven, Green, David L., Gribben, John G., Guitart, Joan, Gur-Cohen, Shiri, Gurbuxani, Sandeep, Gutierrez, Alejandro, Hari, Parameswaran, Harlan, John M., Hartwig, John H., Hayman, Suzanne R., Hayward, Catherine P.M., Hebbel, Robert P., Heslop, Helen E., Hillyer, Christopher D., Hockenbery, David M., Hoffman, Ronald, Horowitz, Mary, Horwitz, Edwin M., Hromas, Robert A., Huang, Franklin W., Isenman, David E., Italiano, Joseph E., Jr., Jaffe, Elaine S., Jagannath, Sundar, Jäger, Ulrich, Jain, Nitin, James, Paula, Jeha, Sima, Jordan, Michael B., Josephson, Cassandra, Jung, Moonjung, Kager, Leo, Kamdar, Kala Y., Kanakry, Jennifer A., Kantarjian, Hagop M., Karafin, Matthew S., Karsan, Aly, Katz, Louis M., Kaufman, Randal J., Kaufman, Richard M., Keller, Frank G., Kelly, Kara M., Kelton, John, Kessler, Craig M., Key, Nigel S., Khandoga, Alexander G., Khanna-Gupta, Arati, Klein, Harvey G., Kollet, Orit, Konkle, Barbara A., Kontoyiannis, Dimitrios P., Koreth, John, Koretzky, Gary A., Kremyanskaya, Marina, Küppers, Ralf, Kuzel, Timothy M., Kwak, Larry W., Lakshmanan, Viswanathan, Landier, Wendy, Lapid, Kfir, Lapidot, Tsvee, Larson, Peter J., Lechner, Klaus, Lee, Andrea, Lee, William M.F., Levi, Marcel, Lewis, Russell E., Liebman, Howard A., Lillicrap, David, Lim, Wendy, Lin, Thomas S., Lindblad, Robert, Lip, Gregory Y.H., Little, Jane A., Loh, Mignon L., Look, A. Thomas, López, José A., Luscinskas, Francis W., Macartney, Christine A., Maciejewski, Jaroslaw P., Maitta, Robert W., Majhail, Navneet S., Manches, Olivier, Mandle, Robert, Mann, Kenneth G., Manno, Catherine S., Marchi, Enrica, Mariani, Guglielmo, Marincola, Francesco M., Marks, Peter W., Mascarenhas, John, Massberg, Steffen, Mauch, Peter M., McCorkle, Ruth, McCrae, Keith R., McEver, Rodger P., McGrath, Emer, McKinney, Matthew S., Meacham, Amy, Menitove, Jay E., Merlini, Giampaolo, Migliaccio, Anna Rita, Miller, Jeffrey S., Mims, Martha P., Mondoro, Traci Heath, Moorehead, Paul, Munshi, Nikhil C., Najfeld, Vesna, Nazi, Ishac, Neff, Anne T., Ness, Paul M., Ng, Andrea K., Notarangelo, Luigi D., O'Brien, Sarah H., O'Connor, Owen A., Donghaile, Diarmaid Ó, O'Donnell, Martin, Otis, Stavroula, Ou, Zhishuo, Pai, Sung-Yun, Palucka, Karolina, Pande, Reena L., Papayannopoulou, Thalia, Pardanani, Animesh, Paredes, Nethnapha, Patriquin, Christopher, Petersdorf, Effie W., Pittaluga, Stefania, Plow, Edward F., Ponce, Doris M., Popolo, Laura, Powell, Leland D., Price, Elizabeth A., Pui, Ching-Hon, Puigserver, Pere, Quintás-Cardama, Alfonso, Rak, Janusz, Ramos, Carlos A., Rand, Jacob H., Ravandi, Farhad, Rawlings, David J., Reddy, Pavan, Reding, Mark T., Rhee, Charles, Rice, Lawrence, Riese, Matthew J., Ritchey, Arthur Kim, Rivella, Stefano, Roberts, David J., Romaguera, Jorge E., Roman, Elizabeth, Rooney, Cliona M., Rosen, Steven T., Rosenthal, David S., Rosovsky, Rachel, Rowley, Scott D., Rydz, Natalia, Sadler, J. Evan, Sandlund, John T., Jr., Sauk, Steven, Saunthararajah, Yogen, Scadden, David, Schaefer, Kristen G., Schiffman, Fred J., Schmaier, Alvin H., Schrier, Stanley L., Schuchman, Edward H., Scullion, Bridget Fowler, Selvaggi, Kathy J., Shaheen, Montaser, Shaz, Beth H., Sheehan, Andrea M., Shelburne, Samuel A., Shlomchik, Mark J., Shurin, Susan B., Silberstein, Leslie E., Silberstein, Lev, Silverstein, Roy L., Sloan, Steven R., Smith, Franklin O., Smith, James, Snyder, Edward L., Soff, Gerald A., Spitzer, Thomas R., Steinberg, Martin H., Stock, Wendy, Stone, Richard M., Storry, Jill R., Strauss, Ronald G., Stroncek, David F., Szczepiorkowski, Zbigniew M., Tiu, Ramon V., Toltl, Lisa J., Toms, Angela, Tormey, Christopher A., Treon, Steven P., Tulpule, Anil, Vedantham, Suresh, Verneris, Michael R., Vichinsky, Elliott P., von Andrian, Ulrich H., Wagner, Andrew J., Wang, Ena, Wang, Jia-huai, Wang, Michael, Warkentin, Theodore E., Wasserstein, Melissa P., Wei, Michael C., Weinstein, Howard J., Weisdorf, Daniel J., Weitz, Jeffrey I., Westhoff, Connie M., Wiley, James S., Williams, David A., Wilson, Wyndham H., Wolfe, Joanne, Wolgast, Lucia R., Wood, Deborah, Wu, YanYun, Yee, Donald L., Young, Ken H., Young, Neal S., Zeldenrust, Steven R., Zhang, Liang, and Zhou, Ming-Ming
- Published
- 2013
- Full Text
- View/download PDF
20. Matrix metalloproteinase‐9 promotes neutrophil and T cell recruitment and migration in the postischemic liver
- Author
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Khandoga, Andrej, Kessler, Julia S., Hanschen, Marc, Khandoga, Alexander G., Burggraf, Dorothe, Reichel, Christoph, Hamann, Gerhard F., Enders, Georg, and Krombach, Fritz
- Abstract
Matrix metalloproteinases‐2 and ‐9 (MMP‐2/9) are critically involved in degradation of extracellular matrix, and their inhibition is discussed as a promising strategy against hepatic ischemia‐reperfusion (I/R) injury. Here, we analyzed the role of MMP‐2 and ‐9 for leukocyte migration and tissue injury in sham‐operated mice and in mice after I/R, treated with a MMP‐2/9 inhibitor or vehicle. Using zymography, we show that the MMP‐2/9 inhibitor abolished I/R‐induced MMP‐9 activation, whereas MMP‐2 activity was not detectable in all groups. As demonstrated by intravital microscopy, MMP‐9 inhibition attenuated postischemic rolling and adherence of total leukocytes in hepatic postsinusoidal venules, CD4+ T cell accumulation in sinusoids, and neutrophil transmigration. These effects were associated with reduction of plasma tumor necrosis factor α (TNF‐α) levels and endothelial expression of CD62P. Motility of interstitially migrating leukocytes was assessed by near‐infrared reflected light oblique transillumination microscopy in the postischemic cremaster muscle. Upon MMP‐9 blockade, leukocyte migration velocity and curve‐line and straight‐line migration distances were reduced significantly as compared with the vehicle‐treated I/R group. Postischemic sinusoidal perfusion failure, hepatocellular apoptosis, and alanine aminotransferase activity were only slightly reduced after MMP‐9 inhibition, whereas aspartate aminotransferase activity and mortality were significantly lower. In conclusion, MMP‐9 is involved in the early recruitment cascades of neutrophils and CD4+ T cells, promotes neutrophil and T cell transmigration during hepatic I/R, and is required for motility of interstitially migrating leukocytes. MMP‐9 blockade is associated with an attenuation of TNF‐α release and endothelial CD62P expression, weakly protects from early microvascular/hepatocellular I/R damage, but improves postischemic survival.
- Published
- 2006
- Full Text
- View/download PDF
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