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Background: Ever since the dawn of modern medical core Surgical practice, the tracheal intubation techniques in Anaesthetic care has rapidly evolved and still evolving into newer modalities. The importance of tracheal intubation in securing airway is obvious and needs no emphasis. Methods: Between February 2022 to January 2023, researchers from the Department of Anesthesiology, Kamineni Academy of Medical Sciences and Research Centre, LB Nagar, Hyderabad, Telangana, India, conducted this clinical trial. The study was approved by the hospital's ethics review board. All patients provided their written informed permission. Sixty patients receiving Awake Fiberoptic Intubation were included, all of whom had been scheduled for elective surgery. Results: An annexed master chart includes the ages and sexes of all study participants, as well as their weights, ASA-PS classifications, cough scores, post-intubation scores, Ramsay sedation scores, oxygen saturations, heart rates and mean arterial pressures before and after intubation. Conclusion: We found that Awake Fiberoptic Intubation with Inj. Dexmedetomidine was associated with improved sedation, intubating conditions and tolerance compared to AFI with Inj. Fentanyl. [ABSTRACT FROM AUTHOR]

Background: To investigate the effects of fentanyl and Clonidine when combined with bupivacaine during spinal anaesthesia for caesarean sections. To assess the length of analgesia by contrasting two groups. To correlate and contrast the two groups', newborn outcomes, hemodynamic effects and post-operative sedation. Material and Methods: A randomized prospective comparative study was performed at Kamineni Academy of Medical Sciences and Research Centre, LB Nagar, Hyderabad in 90 patients undergoing elective or emergency caesarean section. For medication injections, patients were randomly divided into 3 groups of 30. Physiological and demographic characteristics, the beginning of analgesia, the peak of cephalic spread, the upper level of sensory block, and the grade of motor block as determined by the Bromage motor scale were all observed throughout surgery. The mean and standard deviation of the additional results were calculated. Anova tables were used to assess statistical significance. Results: Groups' highest sensory levels were statistically extremely highly significant (P 0.001). In SBP, Three groups did not significantly differ from one another after five minutes (P>0.05). A significantly differed from groups B and C at 15 minutes (P 0.001). B&C, however, did not significantly differ from each other (P>0.05). A&B had a significant difference at 30 minutes (P 0.05). Groups A and B were connected with sedation level 1. Group C was connected to the sedation level 2. The correlations mentioned above were statistically extremely strong (P 0.001). Conclusion: The effectiveness of intraoperative analgesia was enhanced both by the intrathecal clonidine and the clonidine fentanyl combination. In contrast to clonidine alone, the combination of clonidine and fentanyl dramatically enhanced intraoperative analgesic effects and sustained postoperative analgesia. Hemodynamics within the operating room were stable. The analgesia lasted longer than expected. There were hardly any negative effects brought on by the medications' synergistic effects. The course of the foetus was not changed. [ABSTRACT FROM AUTHOR]