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5. Pulmonary vasodilators in patients with advanced chronic kidney disease and pre‐capillary pulmonary hypertension—A case series.

Author

Leguizamon, Raul, McLaren, Ian, John, Tara, Khan, Rasha, Prendergast, Alexander, Wattanachayakul, Phuuwadith, Geller, Andrew, Malin, John, Jarret, Simone A., Lo, Kevin Bryan, Martinez Manzano, Jose Manuel, and Witzke, Christian

Subjects
PULMONARY hypertension, CHRONIC kidney failure, ENDOTHELIN receptors, CARDIAC catheterization, CHRONICALLY ill
Abstract

Pulmonary hypertension (PH) is a prevalent complication among patients with chronic kidney disease (CKD). In these patients, pulmonary vasodilators may be useful but are underused. We describe a group of patients with precapillary PH and advanced CKD treated with pulmonary vasodilators. This was a case series of patients with CKD stage 4 and 5 and precapillary PH (isolated or combined) based on right heart catheterization (RHC) treated with pulmonary vasodilators from 2018 to 2023. Of 263 patients with isolated precapillary or combined PH and advanced CKD, only 17 (6%) were treated with pulmonary vasodilators; 53% (n = 9) with precapillary PH and 47% (n = 8) with combined PH. Most patients (94%, n = 16) received phosphodiesterase‐5 antagonists, while 12% (n = 2) received endothelin receptor antagonists. Adverse clinical outcomes were seen in 35% of patients within a year. The use of pulmonary vasodilator did not prevent adverse outcomes in patients with precapillary PH and advanced CKD. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Association of mildly elevated pulmonary vascular resistance with major cardiovascular events in pulmonary hypertension and chronic kidney disease: A retrospective cohort analysis.

Author

Martinez Manzano, Jose M., Prendergast, Alexander, John, Tara, Leguizamon, Raul, McLaren, Ian, Khan, Rasha, Geller, Andrew, Wattanachayakul, Phuuwadith, Malin, John, Jarrett, Simone A., Lo, Kevin Bryan, Benzaquen, Sadia, and Witzke, Christian

Subjects
PULMONARY hypertension, CHRONIC kidney failure, VASCULAR resistance, MAJOR adverse cardiovascular events, COHORT analysis
Abstract

Pulmonary hypertension (PH) is associated with adverse outcomes in chronic kidney disease (CKD) patients. Our study suggests mildly elevated pulmonary vascular resistance (> 2 to ≤ 3) is independently associated with major adverse cardiovascular events at 1‐year follow‐up. Early diagnosis of precapillary PH in CKD patients can potentially improve clinical outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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16. ASSOCIATION BETWEEN HEPATIC STEATOSIS AND CONGESTIVE HEART FAILURE: ANALYSIS OF THE NHANES 2017 - 2020

Author

Wattanachayakul, Phuuwadith, Polpichai, Natchaya, Lalitnithi, Pakin, Lopimpisuth, Chawin, Rujirachun, Pongprueth, CHIKOVANI, NANO, Suenghataiphorn, Thanathip, Chaisrimaneepan, Nattanicha, Danpanichkul, Pojsakorn, Malin, John, Byfield, Karecia, Khan, Rasha, Idowu, Abiodun Benjamin, Casipit, Carlo Gabriel, Casipit, Bruce Adrian, and Tantisattamo, Ekamol

Published
2024
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17. ASSOCIATION BETWEEN SERUM URIC ACID LEVEL AND CONGESTIVE HEART FAILURE:ANALYSIS OF THE NHANES 2017 - 2020

Author

Wattanachayakul, Phuuwadith, Polpichai, Natchaya, Rujirachun, Pongprueth, Lalitnithi, Pakin, Chaisrimaneepan, Nattanicha, Lopimpisuth, Chawin, Suenghataiphorn, Thanathip, CHIKOVANI, NANO, Malin, John, Danpanichkul, Pojsakorn, Byfield, Karecia, Casipit, Carlo Gabriel, Khan, Rasha, Idowu, Abiodun Benjamin, Casipit, Bruce Adrian, and Tantisattamo, Ekamol

Published
2024
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