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3. Disseminating the Foundations of Knowledge Translation and Patient Engagement Science Through the KnowledgeNudge Blog and Twitter Profile: Quantitative Descriptive Evaluation

Author

Sibley, Kathryn M, Khan, Masood, Roche, Patricia L, Faucher, Patrick, and Leggett, Carly

Subjects
Computer applications to medicine. Medical informatics, R858-859.7, Public aspects of medicine, RA1-1270
Abstract

BackgroundThere is a documented need to build capacity for theory- and evidence-informed knowledge translation (KT) and patient engagement (PE) practice in health research. Dissemination of foundational content online coupled with social media promotion may build capacity by increasing awareness, knowledge, and positive attitudes. ObjectiveThis retrospective study sought to (1) describe exposure and engagement of the KnowledgeNudge KT and PE dissemination strategy (online blog and Twitter profile) over 2 years and (2) identify and compare characteristics of individual posts with the most and least exposure and reach. MethodsExposure was assessed by blog site views per month and Twitter profile impressions per month. Engagement was assessed by Twitter profile interactions per month. Descriptive statistics were calculated for 6-month blocks and compared using one-way analysis of variance or Student t test. Individual post exposure was assessed by average post views per week. Individual post reach was assessed by average post reads per week. High- and low-profile blog posts with the highest and lowest 10th percentile for exposure and reach were identified. ResultsA total of 99 posts and 755 tweets were published during the study period. There was a significant increase in exposure (P=.004) and reach (P

Published
2020
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5. Design of Compact Patch Antenna for TPMS Applications

Author

Ataur Safi Rahaman Laskar, MD., Parvez, Khan Masood, Moinul Haque, SK., Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Bhateja, Vikrant, editor, Chowdary, P. Satish Rama, editor, Flores-Fuentes, Wendy, editor, Urooj, Shabana, editor, and Sankar Dhar, Rudra, editor

Published
2024
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6. Design of Miniaturized and Dual-Band Slot Antenna for Wireless Communications

Author

Ataur Safi Rahaman Laskar, MD., Parvez, Khan Masood, Moinul Haque, SK., Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Bhateja, Vikrant, editor, Chowdary, P. Satish Rama, editor, Flores-Fuentes, Wendy, editor, Urooj, Shabana, editor, and Sankar Dhar, Rudra, editor

Published
2024
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15. Symptoms as a Predictor of the Placebo-Controlled Efficacy of PCI in Stable Coronary Artery Disease

Author

Rajkumar, Christopher, Foley, Michael, Ahmed-Jushuf, Fiyyaz, Simader, Florentina, Ganesananthan, Sashiananthan, Wang, Danqi, Mohsin, Muhammad, Pathimagaraj, Rachel, Macierzanka, Krzysztof, Petraco, Ricardo, Khamis, Ramzi, Cole, Graham, Howard, James, Mayet, Jamil, Francis, Darrel, Kokhar, Arif, Gohar, Aisha, Lampadakis, Ioannis, Seligman, Henry, Kaura, Amit, Nijjer, Sukhjinder, Sen, Sayan, Ramrakha, Punit, Kaprielian, Raffi, Malik, Iqbal, Khan, Masood, Sethi, Amarjit, Foale, Rodney, Keeble, Thomas, Tang, Kare, Davies, John, Gamma, Reto, Clesham, Gerald, Dungu, Jason, Kabir, Alamgir, Nazri, Shah Mohd, O’Kane, Peter, Hinton, Jonathan, Din, Jehangir, Nowbar, Alexandra, Kotecha, Tushar, Haworth, Peter, Spratt, James, Williams, Rupert, Cosgrove, Claudia, Lim, Pitt, Routledge, Helen, Mughal, Lal, Trevelyan, Jasper, Sinha, Manas, Curzen, Nick, Wilkinson, James, Sirohi, Rohit, Calver, Alison, Rawlins, John, Jabbour, Richard, Ruparelia, Neil, Sehmi, Joban, Kinnaird, Tim, Abdul, Fairoz, Panoulas, Vasileios, Collier, David, Thornton, George, Sohaib, Afzal, Al-Lamee, Rasha K., Simader, Florentina A., Rajkumar, Christopher A., Foley, Michael J., Chotai, Shayna, Bual, Nina, Khokhar, Arif, Pathimagaraj, Rachel H., Davies, John R., Keeble, Tom R., O’Kane, Peter D., Spratt, James C., Nijjer, Sukhjinder S., Howard, James P., Harrell, Frank E., Jr., Francis, Darrel P., and Shun-Shin, Matthew J.

Published
2024
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28. Miniaturized Dielectric Disc Loaded Monopole Antenna

Author

Parvez, Khan Masood, Moinul Haque, SK., Minz, Laxmikant, Bansal, Jagdish Chand, Series Editor, Deep, Kusum, Series Editor, Nagar, Atulya K., Series Editor, Das, Nibaran, editor, Binong, Juwesh, editor, Krejcar, Ondrej, editor, and Bhattacharjee, Debotosh, editor

Published
2023
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29. Design of Meandered Slot Antenna for Tire Pressure Monitoring System

Author

Ataur Safi Rahaman Laskar, MD., Parvez, Khan Masood, Moinul Haque, SK., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Rawat, Sanyog, editor, Kumar, Sandeep, editor, Kumar, Pramod, editor, and Anguera, Jaume, editor

Published
2023
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33. Improving the diagnostic yield of prostate cancer

Author

Khan, Masood A.

Abstract

Although the introduction of PSA as a biomarker for detecting prostate cancer has enabled the disease to be diagnosed at an earlier stage, the primary drawback to PSA as a biomarker and basis for prostate cancer screening and diagnosis is its lack of specificity. To address this issue, PSA density, velocity and percent free PSA have all been assessed as potential approaches for improving the diagnosis of prostate cancer, albeit with variable and limited success. These challenges and the desire to improve the management and treatment of patients with prostate cancer prompted studies that investigated the capacity of measuring pro- PSA levels to improve diagnostic yield over that of PSA alone. Our study confirmed that combining pro-PSA, total and percent free PSA improved the specificity of prostate cancer detection from that of 23% for PSA alone to 44%. To further improve the utility of pro-PSA, we subsequently determined that the ratio of pro-PSA and benign-PSA can identify the presence of prostate cancer with greater accuracy when the percent free PSA is below 15%. Traditionally, prostate cancer has been definitively diagnosed by performing transrectal ultrasound (TRUS) guided prostate biopsies. However, such a biopsy technique has a cancer detection rate of less than 30% in a benign feeling prostate. In addition, when TRUS biopsies are repeated due to rising PSA, the cancer detection rate significantly reduces to below 10% for men undergoing a third set of such biopsies. We therefore undertook a study to assess the diagnostic strength of the transperineal template prostate biopsies (TPTPB) in this group of men and demonstrated that the cancer detection rate of the TPTPB is significantly better than that of the TRUS biopsy (52%-68%). We subsequently directly compared TRUS against TPTPB in biopsy naïve men and revealed that TPTPB significantly outperforms TRUS in prostate cancer detection (60% versus 32%). Based on the established concept that there is a reciprocal relationship between cancer and the immune system, and the proposition that the presence of cancer will influence the phenotype of immune cells in the blood which can be detected by profiling peripheral blood mononuclear cells, we subsequently investigated whether profiling the phenotype of immune cells in the blood could further improve our ability not only to detect prostate cancer, but clinically significant prostate cancer. For this, flow cytometric immune profiling of the peripheral blood from men with benign prostate disease and patients with confirmed prostate cancer identified phenotypic features 'fingerprints' within the lymphocyte populations which, when incorporated into machine learning based algorithms, can be used to distinguish between the presence of benign prostate disease and prostate cancer. Furthermore, we identified a panel of eight natural killer (NK) cell phenotypic features which can be used to very accurately differentiate between high risk and low/intermediate risk prostate cancer when incorporated into machine learning algorithms. In summary, over the past two decades, my work has not only resulted in an improvement in the utility of PSA as a biomarker for the detection of prostate, but I also demonstrated that performing transperineal prostate biopsies significantly improves prostate cancer detection. Furthermore, we have recently revealed that our immune system can aid us to differentiate between indolent and clinically significant prostate cancer. Taken together, this programme of work has greatly impacted clinical practice.

Published
2021

38. Expedited transfer to a cardiac arrest centre for non-ST-elevation out-of-hospital cardiac arrest (ARREST): a UK prospective, multicentre, parallel, randomised clinical trial

Author

Perera, Divaka, Clapp, Brian, Prendergast, Bernard, Pavlidis, Antonis, Wragg, Andrew, Byrne, Jonathan, Stephens, Nigel, Rosser, Gareth, Wood, Darryl, Bell, Robert, Kurbaan, Arvinder, Ozkor, Muhiddin, Lampard, Anthony, Papadopoulos, Desiree, Hughes, Johanna, Pendolino, Valentina, Shaw, Joanna, Bannister, Clara, Long, Amy, Kearney, Justin, Palti, Gabriel, Ritches-Price, Joanne, Whitbread, Mark, Adamson, Dawn, Blows, Lucy, Brown, Martin, Lane, Garth, Connor, Michael, Muir, Keith, Chamberlain, Douglas, Morris, Tim, Kwok, Matthew, Knight, Megan, Jerome, Lauren, Nijjer, Sukhjinder, Das, Rita, Sidney, Therese, Bogle, Richard, Roberts, Patrick, Webb, Ian, Spencer, Oliver, Petzer, Edward, Khan, Masood, Marciniak, Maciej, De Belder, Mark, Stables, Rod, Curzen, Nick, Mamas, Mamas, Patterson, Tiffany, Perkins, Gavin D, Perkins, Alexander, Clayton, Tim, Evans, Richard, Dodd, Matthew, Robertson, Steven, Wilson, Karen, Mellett-Smith, Adam, Fothergill, Rachael T, McCrone, Paul, Dalby, Miles, MacCarthy, Philip, Firoozi, Sam, Malik, Iqbal, Rakhit, Roby, Jain, Ajay, Nolan, Jerry P, and Redwood, Simon R

Published
2023
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46. A randomized controlled trial to investigate the use of acute coronary syndrome therapy in patients hospitalized with COVID-19: the COVID-19 Acute Coronary Syndrome trial

Author

Kanagaratnam, Prapa, Francis, Darrel P., Chamie, Daniel, Coyle, Clare, Marynina, Alena, Katritsis, George, Paiva, Patricia, Szigeti, Matyas, Cole, Graham, de Andrade Nunes, David, Howard, James, Esper, Rodrigo, Khan, Masood, More, Ranjit, Barreto, Guilherme, Meneguz-Moreno, Rafael, Arnold, Ahran, Nowbar, Alexandra, Kaura, Amit, Mariveles, Myril, March, Katherine, Shah, Jaymin, Nijjer, Sukhjinder, Lip, Gregory Y.H., Mills, Nicholas, Camm, A. John, Cooke, Graham S., Corbett, Simon J., Llewelyn, Martin J., Ghanima, Waleed, Toshner, Mark, Peters, Nicholas, Petraco, Ricardo, Al-Lamee, Rasha, Boshoff, Ana Sousa Marcelino, Durkina, Margarita, Malik, Iqbal, Ruparelia, Neil, Cornelius, Victoria, and Shun-Shin, Matthew

Published
2023
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