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2. Real-World Comparison of Clopidogrel With Ticagrelor and Prasugrel in Patients With Chronic Coronary Disease Who Underwent Atherectomy

Author

Khan, Mahin R., primary, Koshy, Anoop N., additional, Tanner, Richard, additional, Farhan, Serdar, additional, Vinayak, Manish, additional, Farooq, Ali, additional, Sartori, Samantha, additional, Feng, Yihan, additional, Spirito, Alessandro, additional, Arora, Ayush, additional, Dhulipala, Vishal, additional, Kapur, Vishal, additional, Suleman, Javed, additional, Sharma, Raman, additional, Mehran, Roxana, additional, Kini, Annapoorna, additional, and Sharma, Samin K., additional

Published
2024
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5. Real-World Comparison of Clopidogrel with Ticagrelor and Prasugrel In Patients with Chronic Coronary Disease undergoing Atherectomy

Author

Khan, Mahin R., primary, Koshy, Anoop N., additional, Tanner, Richard, additional, Farhan, Serdar, additional, Farooq, Ali, additional, Sartori, Samantha, additional, Feng, Yihan, additional, Spirito, Alessandro, additional, Arora, Ayush, additional, Dhulipala, Vishal, additional, Vinayak, Manish, additional, Kapur, Vishal, additional, Suleman, Javed, additional, Sharma, Raman, additional, Mehran, Roxana, additional, Kini, Annapoorna, additional, and Sharma, Samin K., additional

Published
2023
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19. TELE-BASED VIRTUAL BP MANAGEMENT BY PHARMACIST OR NURSE PRACTITIONER VERSUS OFFICE-BASED PCP LED INTERVENTION IN MANAGEMENT OF SYSTOLIC BP. A SYSTEMATIC REVIEW AND META-ANALYSIS

Author

Baral, Nischit, primary, Javvadi, Sri Lakshmi Pratyusha, additional, Abdelazeem, Basel, additional, Khan, Ashiya, additional, Rao, Deepti Nagaraja, additional, Bashyal, Krishna Prasad, additional, Rauniyar, Rohit, additional, Adhikari, Govinda, additional, Ghimire, Calvin, additional, Htwe, Khaing Khaing, additional, Aykent, Kazim, additional, Kunadi, Arvind, additional, Khan, Hafiz, additional, and Khan, Mahin R., additional

Published
2022
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22. OUTCOMES OF HOSPITALIZED PATIENTS WITH ACUTE ISCHEMIC STROKE AND CONCOMITANT NSTEMI - ANALYSIS FROM 2016-2019 NATIONAL INPATIENT SAMPLE

Author

Kambalapalli, Soumya, primary, Baral, Nischit, additional, Seri, Amith Reddy, additional, Khan, Mahin R., additional, Abdelazeem, Basel, additional, Khan, Hafiz, additional, Htwe, Khaing Khaing, additional, Rauniyar, Rohit, additional, Adhikari, Govinda, additional, Khan, Ashiya, additional, Kunadi, Arvind, additional, Changezi, Hameem U., additional, and Munir, Ahmad, additional

Published
2022
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23. TRENDS AND OUTCOMES OF ACUTE HEART FAILURE WITH UNDERLYING AMYLOIDOSIS - A RETROSPECTIVE COHORT STUDY FROM 2016-2019 NATIONAL INPATIENT SAMPLE DATABASE

Author

Khan, Ashiya, primary, Baral, Nischit, additional, Seri, Amith Reddy, additional, Khan, Mahin R., additional, Khan, Hafiz, additional, Abdelazeem, Basel, additional, Adhikari, Govinda, additional, Rauniyar, Rohit, additional, Htwe, Khaing Khaing, additional, Kunadi, Arvind, additional, and Changezi, Hameem U., additional

Published
2022
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26. TRENDS IN MORTALITY, USE OF TEMPORARY MECHANICAL CIRCULATORY SUPPORT MODALITIES, RESOURCE UTILIZATION & READMISSION RATES FOR TAKOTSUBO CARDIOMYOPATHY ASSOCIATED CARDIOGENIC SHOCK

Author

Ali, Shafaqat, Kumar, Manoj, Duhan, Sanchit, Farooq, Faryal, Keisham, Bijeta, Sultan, Muhammad, Afzal, Muhammad Sohaib, Nasir, Bilal, Manan, Malalai, Thotamgari, Sahith Reddy, Abdul, Karim Amidou, Surapaneni, Phani, Aamir, Muhammad, Khan, Mahin R., Changezi, Hameem U., Munir, Ahmad, Helmy, Tarek, and Modi, Kalgi A.

Published
2024
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28. Rivaroxaban is Comparable to Warfarin in Prevention of Thromboembolism in Patients with Non-Valvular Atrial Fibrillation with Valvular Heart Disease: A Systematic Review and Meta-analysis

Author

Baral, Nischit, primary, Katel, Anjan, additional, Adhikari, Govinda, additional, Khan, Mahin R., additional, Khan, Hafiz M. W., additional, Rauniyar, Rohit, additional, Akanbi, Maxwell, additional, Malik, Bilal, additional, Ahmad, Muhammad, additional, Khan, Ashiya, additional, Abdelazeem, Basel, additional, Savarapu, Pramod, additional, Isa, Sakiru O., additional, Kunadi, Arvind, additional, Sud, Parul, additional, and Changezi, Hameem U., additional

Published
2021
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29. Systematic Review and Meta-Analysis: Can We Compare Direct Oral Anticoagulants to Warfarin in Patients With Atrial Fibrillation and Bio-Prosthetic Valves?

Author

Adhikari, Govinda, primary, Baral, Nischit, additional, Rauniyar, Rohit, additional, Karki, Sandip, additional, Abdelazeem, Basel, additional, Savarapu, Pramod, additional, Isa, Sakiru, additional, Khan, Hafiz Muhammad Waqas, additional, Khan, Mahin R, additional, and Changezi, Hameem U, additional

Published
2021
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31. Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention in Patients with Left Ventricular Systolic Dysfunction

Author

Khan, Mahin R., primary, Kayani, Waleed T., additional, Pelton, Jason, additional, Ansari, Ahmed, additional, Paniagua, David, additional, Khalid, Umair, additional, Denktas, Ali, additional, Changezi, Hameem U., additional, Munir, Ahmad, additional, Jimenez, Ernesto, additional, Alam, Mahboob, additional, and Jneid, Hani, additional

Published
2020
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35. Effect of increasing age on percutaneous coronary intervention vs coronary artery bypass grafting in older adults with unprotected left main coronary artery disease: A meta‐analysis and meta‐regression

Author

Khan, Mahin R., primary, Kayani, Waleed T., additional, Ahmad, Waqas, additional, Manan, Malalai, additional, Hira, Ravi S., additional, Hamzeh, Ihab, additional, Jneid, Hani, additional, Virani, Salim S., additional, Kleiman, Neal, additional, Lakkis, Nasser, additional, and Alam, Mahboob, additional

Published
2019
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37. COMPARISON OF PERCUTANEOUS CORONARY INTERVENTION VERSUS CORONARY ARTERY BYPASS GRAFTING IN OLDER ADULTS WITH UNPROTECTED LEFT MAIN CORONARY ARTERY DISEASE: A META-ANALYSIS AND METAREGRESSION

Author

Khan, Mahin R., primary, Kayani, Waleed T., additional, Ahmad, Waqas, additional, Siddiqui, Sadar, additional, Shahzad, Saima A., additional, Mumtaz, Shazhad A., additional, Manan, Malalai, additional, Hira, Ravi S., additional, Hamzeh, Ihab, additional, Jneid, Hani, additional, Virani, Salim S., additional, Kleiman, Neal, additional, and Alam, Mahboob, additional

Published
2019
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39. Abstract 16607: A Comparison Of Outcomes Between Patients At Low And Intermediate-risk With Aortic Stenosis Undergoing Transcatheter Or Surgical Valve Repair

Author

Khan, Mahin R, Kayani, Waleed T, Manan, Malalai, Munir, Ahmad, Hamzeh, Ihab, Virani, Salim S, Birnbaum, Yochai, Jneid, Hani, and Alam, Mahboob

Abstract

Introduction:In view of paucity of robust data and to improve precision of effect size, we aim to compare safety and efficacy of transcatheter aortic valve replacement (TAVR) with surgical aortic valve replacement (SAVR) in patients with aortic stenosis (AS) at low-intermediate risk.Methods:We performed an aggregate data meta-analysis of 7 RCTs (6778 patients) comparing TAVR with SAVR for AS in low-intermediate risk patients (Society of Thoracic Surgeons risk score ?8%), with inter-group comparisons of clinical outcomes between studies reporting outcomes in low and intermediate-risk patients using random-effects model. Our primary outcome was all-cause mortality at 30-days, 1-year and 2-years of follow up. Secondary outcomes included cardiac mortality, stroke, acute kidney injury (AKI), atrial fibrillation (AF), permanent pacemaker (PPM) implantation, major bleeding, moderate-severe paravalvular leak (PVL) and re-hospitalisation.Results:All-cause mortality, cardiac mortality and stroke rates were comparable between the two groups at all follow-up periods. TAVR was associated with a lower risk of AKI (OR 0.37 [0.25-0.54]). AF was higher with SAVR at 30-day (OR-0.17 [0.12-0.24]) thorough to 2-years (OR-0.34 [0.21-0.55]), while PPM implantation was higher with TAVR (30-days: OR-3.31 [1.64-6.66], 2-years: OR-3.17 [1.02-9.86]). Moderate-severe PVL was more prevalent with TAVR at all follow-ups. On inter-group comparison, patients in the low-risk group had an even lower risk of AF and re-hospitalization but a higher risk of PPM implantation compared to patients at intermediate-risk undergoing TAVR.Conclusion:TAVR may be an acceptable option for AS in low-intermediate risk patients in view of current data but longer-term follow-up is needed to weigh the overall effect of factors such as AF, PPM implantation and PVL on morbidity and mortality.

Published
2019
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41. A case report of absolute thrombocytopenia with ticagrelor.

Author

Khan MR, Adhikari G, Khan H, and Changezi HU

Abstract

Background: We report a rare case of absolute thrombocytopenia with ticagrelor after 6 h of single loading dose of ticagrelor., Case Summary: A 68-year-old male with ischaemic cardiomyopathy, hypertension, and dyslipidaemia presented with chest pain. He was found to be in new-onset atrial flutter and ruled in for a non-ST-segment elevation myocardial infarction. An echocardiogram showed decreased left ventricular ejection fraction, estimated at 15-20% and serum troponin peaked at 0.2 ng/dL, baseline platelet count was 203 × 10 3 /µL. He underwent a drug-eluting stent placement to the right coronary artery with excellent angiographic results. He received 3000 units of unfractionated heparin and 180 mg of ticagrelor during the procedure. About 6 h after the procedure, he had coffee ground emesis. A complete blood count revealed a platelet count of 2 × 10 3 and 0 × 10 3 /µL on repeat testing. Peripheral smear did not show any evidence of platelet clumping and schistocytes, serum haptoglobin and lactate dehydrogenase were normal. Ticagrelor and heparin were discontinued, while the aspirin was continued. Five units of platelet were transfused. The platelet count improved to 200 × 10 3 /µL. Since his CHADS 2 VASC score was 3, he was discharged on apixaban and clopidogrel in addition to other medication. No thrombocytopenia was seen on outpatient follow-up., Discussion: The common side effects of ticagrelor include bleeding, dyspnoea, gynaecomastia, and rarely thrombotic thrombocytopenic purpura. Although extremely rare, absolute or profound thrombocytopenia can occur with ticagrelor, hours after administration and should be considered when other potential causes of thrombocytopenia have been ruled out., (© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology.)

Published
2020
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