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Background: Human papillomavirus (HPV) is one of the most prevalent sexually transmitted diseases worldwide. The present review was conducted to accumulate evidence on the relationship between cervicovaginal human papillomavirus infection and serum vitamin D status., Methods: Electronic databases including Web of Science, Embase, Scopus, and PubMed were searched by different combinations of keywords related to "human papillomavirus" and "vitamin D", obtained from Mesh and Emtree with AND, and OR operators without any time restriction until December 24, 2022. Selection of articles was based on the inclusion and exclusion criteria. Newcastle-Ottawa Scale was used for quality assessment. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist was applied for reporting., Results: In total, 276 citations were retrieved. After removing duplicates, and non-related articles, the full texts of 7 articles were reviewed including 11168 participants. Three studies reported that there was a positive relationship between vitamin D deficiency and cervicovaginal human papillomavirus while three studies did not. One study showed a significant positive association between higher vitamin D stores and short-term high-risk human papillomavirus persistence., Conclusions: The findings showed no firm evidence for any association between serum vitamin D level and cervicovaginal human papillomavirus infection, although the possible association could not be discarded. Further investigations are needed to reach sound evidence., (© 2024. The Author(s).)

Background: Falls are a primary cause of injuries and hospitalization in older adults. It has been reported that cognitive impairments and dementia can increase fall risk in the older population; however, it remains unknown if fall risk differs among subgroups of dementia. This meta-analysis summarized previous studies reporting the annual fall risk of people with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and compared the fall risk between these two groups of people with dementia., Methods: Thirty-five studies enrolling 7844 older adults with AD or MCI were included. The annual fall prevalence and average number of falls of the included studies were meta-analyzed and compared by random-effects models with inverse variance weights., Results: The annual fall prevalence in people with AD (43.55%) was significantly higher than MCI (35.26%, p < 0.001). A χ 2 test indicated that the pooled fall prevalence is significantly higher in people with AD than MCI χ 2 = 158.403, p < 0.001). Additionally, the yearly average number of falls in AD was higher than in MCI (1.30 vs 0.77 falls/person)., Conclusions: The results showed that older people with AD experience a higher annual fall prevalence with a larger number of falls than older adults with MCI. The results suggested that the fall risk measurements should be reported separately between people with AD and MCI. The findings could provide preliminary guidance for the identification of individuals with dementia who experience a high fall risk., Competing Interests: CONFLICTS OF INTEREST The authors declare that they have no conflicts of interest.

Injuries in professional soccer are a significant concern for teams, and they are caused amongst others by high training load. This cohort study describes the relationship between workload parameters and the occurrence of non-contact injuries, during weeks with high and low workload in professional soccer players throughout the season. Twenty-one professional soccer players aged 28.3 ± 3.9 yrs. who competed in the Iranian Persian Gulf Pro League participated in this 48-week study. The external load was monitored using global positioning system (GPS, GPSPORTS Systems Pty Ltd) and the type of injury was documented daily by the team's medical staff. Odds ratio (OR) and relative risk (RR) were calculated for non-contact injuries for high- and low-load weeks according to acute (AW), chronic (CW), acute to chronic workload ratio (ACWR), and AW variation (Δ-Acute) values. By using Poisson distribution, the interval between previous and new injuries were estimated. Overall, 12 non-contact injuries occurred during high load and 9 during low load weeks. Based on the variables ACWR and Δ-AW, there was a significantly increased risk of sustaining non-contact injuries ( p < 0.05) during high-load weeks for ACWR (OR: 4.67), and Δ-AW (OR: 4.07). Finally, the expected time between injuries was significantly shorter in high load weeks for ACWR [1.25 vs. 3.33, rate ratio time (RRT)] and Δ-AW (1.33 vs. 3.45, RRT) respectively, compared to low load weeks. The risk of sustaining injuries was significantly larger during high workload weeks for ACWR, and Δ-AW compared with low workload weeks. The observed high OR in high load weeks indicate that there is a significant relationship between workload and occurrence of non-contact injuries. The predicted time to new injuries is shorter in high load weeks compared to low load weeks. Therefore, the frequency of injuries is higher during high load weeks for ACWR and Δ-AW. ACWR and Δ-AW appear to be good indicators for estimating the injury risk, and the time interval between injuries., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Nobari, Khalili, Zamorano, Bowman and Granacher.)

Health systems are recognised as playing a potentially important role in many risk management strategies; however, there is strong evidence that health systems themselves have been the victims of unanticipated risks and have lost their functionality in providing reliable services. Existing risk identification and assessment tools in the health sector, particularly in the blood supply chain, address and evaluate risks without taking into account their interdependence and a holistic perspective. As a result, the aim of this paper is to develop a new systemic framework based on a semi-quantitative risk assessment approach to measure supply chain risks, which will be implemented through a case study on the Iranian BSC. This paper identifies and assesses supply chain risks (SCRs) by employing a novel systemic process known as SSM-SNA-ISM (SSI). First, the supply chain and its risks are identified using Soft Systems Methodology (SSM). Then, given the large number of risks, the second stage uses Social Network Analysis (SNA) to identify the relationships between the risks and select the most important ones. In the third stage, risk levelling is performed with a more in-depth analysis of the selected risks and the application of Interpretive Structural Modelling (ISM), and further analysis is performed using the Cross-Impact Matrix Multiplication Applied to Classification (MICMAC). The study found that by using the new proposed approach, taking into account risk relationships, and taking a holistic view, various supply chain risks could be assessed more effectively, especially when the number of risks is large. The findings also revealed that resolving the root risks of the blood supply chain frequently necessitates management skills. This paper contributes to the literature on supply chain risk management in two ways: First, a novel systemic approach to identifying and evaluating risks is proposed. This process offers a fresh perspective on supply chain risk modelling by utilising systems thinking tools. Second, by identifying Iranian BSC risks and identifying special risks.

Ankle sprain is a common musculoskeletal injury, and recurrent ankle sprains often lead to ankle instability. This study aimed to examine whether a 6-week balance training on a wobble board (WB) combined with kinesio taping (KT) is effective in improving balance, postural stability, and ankle stability among female athletes with functional ankle instability (FAI). Twenty-four female athletes with FAI were randomly assigned to study (SG) or control groups (CG). SG attended a 6-week training protocol of combined balance training on the wobble board with KT applied to ankles during exercise. CG only went through a 6-week balance training procedure that was the same as the SG. Before and after the training program, balance and postural stability and the severity of ankle instability were assessed by single-leg Biodex Balance system and Cumberland Ankle Instability Tool (CAIT), respectively. The analysis revealed that the scores of balance and postural stability decreased after the 6-week training for CG ( p = 0.002) and SG ( p = 0.001), which indicates an improvement for these variables, and the score of CAIT increased, which means the severity of instability reduced ( p = 0.001 for both groups). Significant between-group differences were found for balance and postural stability ( t = 2.79, p = 0.011, g = -1.99) and the severity of instability ( t = 2.082, p = 0.049, g = 1.36), favoring SG compared with CG. This study showed that the addition of KT to balance training is more effective than balance training alone in improving balance, postural stability, and severity of ankle instability in female athletes with FAI. Our findings could provide a preliminary reference for designing combined balance and KT programs for delivering health benefits to females with FAI.

The COVID-19 pandemic has had a significant impact on hospitals and healthcare systems around the world. The cost of business disruption combined with lingering COVID-19 costs has placed many public hospitals on a course to insolvency. To quickly return to financial stability, hospitals should implement efficiency measure. An average technical efficiency (ATE) model made up of data envelopment analysis (DEA) and stochastic frontier analysis ( SFA ) for assessing efficiency in public hospitals during and after the COVID-19 pandemic is offered. The DEA method is a non-parametric method that requires no information other than the input and output quantities. SFA is a parametric method that considers stochastic noise in data and allows statistical testing of hypotheses about production structure and degree of inefficiency. The rationale for using these two competing approaches is to balance each method's strengths, weaknesses and introduce a novel integrated approach. To show the applicability and efficacy of the proposed hybrid VRS-CRS-SFA ( VCS ) model, a case study is presented.

Stroke is the biggest cause of adult disability and the third biggest cause of death in the US. Stroke is a medical emergency, and the treatment given in the early hours is important in shaping the patient's long-term recovery and prognosis. Despite the fact that substantial attention has been dedicated to this complex and difficult issue in healthcare, novel strategies such as operation research-based approaches have hardly been used to deal with the difficult challenges associated with stroke. This study proposes a novel approach with data envelopment analysis (DEA) and multi-objective linear programming (MOLP) in hospitals that provide stroke care services to select the most efficient approach, which will be a new experiment in literature perception. DEA and MOLP are widely used for performance evaluation and efficiency measurement. Despite their similarities and common concepts, the two disciplines have evolved separately. The generalised DEA (GDEA) cannot incorporate the preferences of decision-makers (DMs) preferences and historical efficiency data. In contrast, MOLP can incorporate the DM's preferences into the decision-making process. We transform the GDEA model into MOLP through the max-ordering approach to (i) solve the problem interactively; (ii) use the step method (STEM) and consider DM's preferences; (iii) eliminate the need for predetermined preference information; and (iv) apply the most preferred solution (MPS) to identify the most efficient approach. A case study of hospitals that provide stroke care services is taken as an example to illustrate the potential application of the proposed approach method.

Excessive daily training load (TL) can affect the musculoskeletal system health of youth elite soccer players. The purposes of this study were (i) to describe the TL and session rating of perceived exertion (s-RPE) throughout the competition season; (ii) to analyze the weekly (w) differences of acute (daily) workload (wAWL), chronic workload (wCWL), acute-chronic workload ratio, training monotony (wTM), and training strain (wTS) among three periods over the season (early-, mid-, and end-season) by playing position; and (iii) to compare the TL variables during competition periods for the whole team. Twenty young elite soccer players in the under-14 category participated in this study. The game positions were considered as six wide defenders and wide midfielders (WM), five central defenders and central midfielders, and four strikers (ST). Daily monitoring was continued for 26 weeks during a full competition season. According to the league schedule, the season was divided into three periods: early-season from w1 to w8, mid-season from w9 to w17, and end-season from w18 to w26. The main results were that the higher TLs were detected in the early- and mid-season. There was a wAWL and wCWL decrease for all playing positions from early- to mid- and end-season, but the wCWL change was significant only from early- to mid-season ( p ≤ 0.05). For all playing positions but ST, there was a considerable wTM increase from early- to mid-season. When compared with all other playing positions in terms of wAWL and wCWL, WM showed significantly greater values ( p ≤ 0.05). Throughout the season periods, all workload indicators showed a considerable reduction, although there was a significant increase in the three other workload-derived variables (all with p ≤ 0.05) and namely: (i) wACWLR from mid- to end-season; (ii) wTM from early- to mid- and end-season; and (iii) wTS from early- to mid-season. Daily training load and s-RPE had significant fluctuations during all macrocycles of the competition season ( p ≤ 0.05). In addition, in the mid-season, wTM and wTS were higher. Training load monitoring (in terms of, e.g., wAWL, wCWL, and s-RPE) could be the key for coaches of soccer teams to prevent overtraining and injury, especially in U-14 players, who are more susceptible to being affected by high workload.

Soccer is a popular team sport and highly demanding activity that requires high effort and long-term training plans. The goals of this study were to compare the accelerations, decelerations and metabolic power between official and friendly full matches, between the first and second halves of the matches, and between both halves of official and friendly matches. Twelve professional soccer players (age, 28.6 ± 2.7 years; height, 182.1 ± 8.6 cm; body mass, 75.3 ± 8.2 kg; BMI, 22.6 ± 0.7 kg/m 2 ) participated in this study. A total of 33 official and 10 friendly matches were analyzed from the Iranian Premier League. All matches were monitored using GPSPORTS systems Pty Ltd. The following variables were selected: total duration of the matches, metabolic power, accelerations Zone1 (<2 m·s -2 ) (AccZ1), accelerations Zone2 (2 to 4 m·s -2 ) (AccZ2), accelerations Zone3 (>4 m·s -2 ) (AccZ3), decelerations Zone1 (<-2 m·s -2 ) (DecZ1), decelerations Zone2 (-2 to -4 m·s -2 ) (DecZ2) and decelerations Zone3 (>-4 m·s -2 ) (DecZ3). The major finding was shown in metabolic power, where higher values occurred in friendly matches ( p < 0.05 with small effect size). Furthermore, total duration, AccZ3, DecZ1, DecZ2, and DecZ3 were revealed to be higher in official matches, while AccZ1 and AccZ2 were higher in friendly matches. The second half of the official matches revealed higher values for total duration compared to friendly matches ( p < 0.05, moderate effect size). In conclusion, this study observed higher values of metabolic power in friendly matches compared to official matches. AccZ3, DecZ1, DecZ2, and DecZ3 were higher in official matches, while AccZ1 and AccZ2 were higher in friendly matches.

The hypothesis for the research described in this article was that viewing an interactive two-dimensional (2D) or three-dimensional (3D) stereoscopic pre-laboratory video would improve efficiency and learning in the laboratory. A first-year DVM class was divided into 21 dissection teams of four students each. Primary variables were method of preparation (2D, 3D, or laboratory manual) and dissection region (thorax, abdomen, or pelvis). Teams were randomly assigned to a group (A, B, or C) in a crossover design experiment so that all students experienced each of the modes of preparation, but with different regions of the canine anatomy. All students were instructed to study normal course materials and the laboratory manual, the Guide, before coming to the laboratory session and to use them during the actual dissection as usual. Video groups were given a DVD with an interactive 10-12 minute video to view for the first 30 minutes of the laboratory session, while non-video groups were instructed to review the Guide. All groups were allowed 45 minutes to dissect the assigned section and find a list of assigned structures, after which all groups took a post-dissection quiz and attitudinal survey. The 2D groups performed better than the Guide groups (p=.028) on the post-dissection quiz, despite the fact that only a minority of the 2D-group students studied the Guide as instructed. There was no significant difference (p>.05) between 2D and 3D groups on the post-dissection quiz. Students preferred videos over the Guide.