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To analyse any text with regard to logical considerations is how one approaches the text intent and aim of the writer. This research project takes a practical and stylistic look at the poem "Sometimes I Cry" by Tupac Shakur. This research aims to shed light on the stylistic deployment of pragmatic ideas in literary and, more specifically, dramatic speech. This research examines the pragmatics of Tupac Shakur's poem by applying an eclectic theory based on the works of Searle (1979) and Grice (1975), as well as Cruse (2006) for deixis: the Thus, Searle's categorization of SA as realistic, expressive, directorial, commissioned, and declared is scrutinised for each poem's analysis. Grice's tenets (quality, quantity, style, and relationship) are also investigated in each piece to see how much the poet relied on and disliked them to deliver his message. Each poem's translation was examined via the lens of five different types of deixis (personal, time, place, social, and discourse). Thus, the study seeks to analyse the texts of the chosen poem through the use of pragmatic methods in order to determine the poet's style, which is how the right comprehension of the writing can be attained, as well as to determine the most common kinds of language acts a poet uses, to demonstrate how non-compliance with concepts generate stylistic impact on two levels of collaboration in Tupac the rapper Shakur's poem, and to identify types of deixis. This research needs to draw the following conclusions about communication acts: 1) speech actions that are expressive are more common compared to different types. The poet dislikes the majority of Grice's maxims, qualitative maxim being the most prominent of these. The third reason is because the poet mostly used temporal deixis. (4) Tupac Shakur, the rapper, and other lexical components in the poem only employ Grice's three maxims to express ideas and meanings indirectly. [ABSTRACT FROM AUTHOR]

Background: Immune checkpoint inhibitors (ICIs) have been proven to be very effective in the treatment of multiple cancers. They have a unique side-effect profile distinct from conventional chemotherapy that can manifest as immune-related adverse events (irAEs). With expanding ICI use, clinicians will increasingly encounter irAEs, and thus adequate physician knowledge on their recognition and management is crucial., Methods: To assess physician knowledge of irAEs due to ICIs, an online survey was administered to resident physicians in internal medicine (IM), emergency medicine, and family medicine (FM), as well as to faculty physicians in IM and FM., Results: We sent the survey to 413 physicians and received responses from 155 (38%), of which 110 were residents and 45 were faculty. Pembrolizumab was identified as an ICI by 79% of physicians, nivolumab by 64%, and ipilimumab by 55%. Twenty-five percent incorrectly thought infliximab and adalimumab were ICIs. Most physicians (93%) were able to identify the gastrointestinal tract as an irAE site, whereas only 57% and 67% were able to identify cardiovascular and renal systems as irAE sites, respectively. A total of 59% believed steroids negatively affect efficacy of ICIs and should be used with caution to treat irAEs, 65% incorrectly thought endocrinopathies due to irAEs are usually reversible, and 45% of FM residents considered antibiotics as the mainstay of treatment in ICI-mediated colitis. On a self-rated scale from 0 to 100, the median comfort level for all physicians in recognizing irAEs was 15 and for treatment of irAEs was 10., Conclusions: Significant knowledge gaps exist among residents and faculty physicians across multiple specialties regarding the recognition and treatment of irAEs due to ICIs. Given that these physicians are usually the first point of contact with patients, physician education on identification and treatment of irAEs is needed. Early detection of these toxicities is critical for their resolution.