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Smokeless tobacco (ST) is a tobacco product that is used by means other than smoking. Evidence was available that ST products is a known risk factor for oral precancerous and cancers for long, with greater risk for oral cancer than others. The prospective, descriptive study has carried out to evaluate the relationship between the use of smokeless tobacco and oral cancer.Biopsy samples have collected from 60 patients, whose have attended to Al-Gamhouria Teaching Hospital and histo-pathological private labs in Aden using a questionnaire during the period of 12 months. The sections from paraffin-embedded tissue specimens were stained with hematoxylin and eosin (H & E). A section containing the full thickness of the tumors have used for histopathological grading.The prevalence of oral squamous cell carcinoma (OSCC) lesions showed different grade of differentiation among 60 studied patients cases, the Well differentiation squamous cell carcinoma (WDSCC) was the highest percentage (70%). No significant difference noticed in well-differentiated SCCs (WDSCC) between men (36.7%) and women (33.3 %; P < 0.05). The moderate differentiation SCC (MDSCC), and the poor differentiation SCC (PDSCC) represented (20% & 10%) respectively. According to the age of patients, WDSCC, MDSCC and PDSCC highest percentage age group was (51-60) years. Male were predominant in both genders, male to female ratio 1.2: 1. Anatomical sites of all OSCC lesions had analyzed and revealed that tongue was the most prevalent site (33.3%), followed by the buccal mucosa, (23.3%) , floor of mouth (16.7%) , lip (13.3%), Gingiva (8.3%), and the least prevalent site was the hard palate represented (5%) of all cases., the chief etiological factor which we observed, was tobacco, in the form of smoking tobacco used by 75% of the patients followed by smokeless tobacco product users, in form of shamma chewers, (61.7%), and in form of Hot sachet (58.3%), and Zarda users represented 51.7% of cases.Our results indicate that the occurrence of OSCC among studied cases showed different grade of differentiation, age and gender have some relation with the presence of OSCC. and it is high association with risk habits of tobacco use in different forms particularly smokeless tobacco.

The study was carried out to determine antibacterial resistance profiles of methicillin-resistant Staphylococcus aureus (MRSA) isolates from clinical samples of patients during the duration, from January 2019 to July 2020 in five governmental and private medical laboratories of Aden governorate, Yemen. A total of 267 MRSA isolates were tested with a disc diffusion method from 4 clinical specimens. The isolates were examined for methicillin resistance using vancomycin, erythromycin, amikacin, and gentamicin. The results revealed a large number of MRSA isolates showed resistance to erythromycin (43.5%) and Vancomycin (28%). A lower number of MRSA isolates showed resistance to amikacin (6.25%), gentamicin (11.75%). A majority of MRSA isolates were from urine specimen (162) followed by (56) wounds, (34) pus, and (25) semen specimens. The highest proportion of MRSA isolates were obtained from Al-medina medical laboratory (31%) and Alborg laboratory (24%).

During march – May 2020, chikungunya (CHIK), an arboviral infection, has spread throughout the all area of Aden and Lahj governorate, infecting thousands of people.The study investigated haematological parameters and Clinical features of CHIK virus infected patients attending outpatient clinic at Al-shafa and Algamaheer medical center, Aden and Lahj, Yemen. 50 selected patients within the age of 14- 60 years were involved in the study according to the clinical features. The most common feature of the CHIKV infection was arthralgia and high fever. Other clinical manifestations reported as, headache, joint pain, redness of joints , swelling of joints vomiting and Fatigue Blood samples were collected and analyzed using Sysmex automated haematology analyzer for CBC test.Results showed the emergence of lymphopenia (15.7 ± 6.18%) , neutrophils (73.8 ± 6.98%) and the complete white blood cell (WBC) counts was 4.8 ± 1.4 103/μL in patients. The platelets (PLT) counts ranged from 92-244 103/μL (mean: 160 ± 47.4x103/μL). The hemoglobin decreased in 30 % of cases and was about (10 ± 1.2 g/dl) in children. By day 5 of illness the neutrophil and lymphocyte count had recovered to normal range, but the arthralgia and joint pain was continued for weeks. In addition of Clinical features, the neutrophils and lymphopenia was the main hematological indices of CHIK, in lack of CHIK antigen detection

Ciprofloxacin (CIP) is classified as a second-generation fluoroquinolone structurally similar to nalidixic acid. It is a widely used antibiotic to treat different types of bacterial infections. The present study was carried out to evaluate the antimicrobial activity of three different dosage forms of CIP [tablets (Tab coded I, II, III), CIP infusion (Infusion coded I, II, III) and CIP eye drop (Eyedrop coded I, II, III)]. Three most commonly prescribed and dispensed brands for each dosage form were selected. All studied brands were within their shelf life. All brands examined by spectroscopy and the quantity of the active ingredients was with the permitted limits of British pharmacopeia (95-105%). The disk diffusion method was used to evaluate the antimicrobial activity of CIP against E. coli and Staphylococcus Aureus. The highest inhibition zone was at low concentration against E. coli, by Tab-II, Tab-I, and Tab-III tablets respectively. While in the case of infusion, the Infusion-III showed the highest inhibition zone, followed by Infusion-I and Infusion-II. In the case of Staphylococcus Aureus, all Tab I, II, and III have similar potency. At low concentration, Infusion II, III indicated similar while Infusion I had lower potency. However, all brands had slightly higher potency over the standard. All brands of eye drops showed nearly similar potencies against Staphylococcus Aureus with a slight superiority of Eyedrop-I over Eyedrop-II then Eyedrop-III in the highest concentration. All the brands of eye drops showed antimicrobial activity slightly lower than standard. Post-marketing surveillance is an essential issue to distinguish poor-quality medicines. The current study revealed that the marketed CIP pharmaceutical dosage forms showed reasonable antimicrobial activity except for the eyedrops dosage forms which showed slightly lower inhibition zone in comparison to standard

The present study aimed to evaluate the changes in WBC and platelet count and detection of NS1 antigen, IgM and IgG antibodies in dengue patients. There were 103 confirmed cases of dengue including 49(47.6%) females and 54(52.4%) males. The WBC count was less than (2000 /μl) in 16 cases and was ranging between (2000-4000 /μl) in 44 cases. The platelets count decreased to