281 results on '"Khajavi, Alireza"'
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2. Availability and affordability of antidiabetic medicines in Herat of Afghanistan in 2023
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Tajik, Amirmohammad, Varmaghani, Mehdi, Ghavami, Vahid, Saeedi, Nasrin, Sharifi, Farshad, Khajavi, Alireza, and Satarzadeh, Laleh
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- 2024
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3. Determinants and economic burden of HIV/AIDS in Iran: a prospective study
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Reshadat-Hajiabad, Tahmineh, Khajavi, Alireza, Hosseinpour, Ali Mohammad, Bojdy, Amin, Hashemi-Meshkini, Amir, and Varmaghani, Mehdi
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- 2023
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4. Metabolic effects of dopamine-agonists treatment among patients with prolactinomas
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Kabootari, Maryam, Shirmohammadli, Habibeh, Golgiri, Fatemeh, Mosalamiaghili, Seyedarad, Khajavi, Alireza, and Akbari, Hamideh
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- 2023
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5. Impact of short- and long-term exposure to air pollution on lipid profile in adults aged 20 to 69 years in Tehran Province, Iran
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Tamehri Zadeh, Seyed Saeed, Khajavi, Alireza, Tohidi, Maryam, Azizi, Fereidoun, and Hadaegh, Farzad
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- 2023
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6. The impact of long-term exposure to PM10, SO2, O3, NO2, and CO on incident dysglycemia: a population-based cohort study
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Tamehri Zadeh, Seyed Saeed, Khajavi, Alireza, Ramezankhani, Azra, Azizi, Fereidoun, and Hadaegh, Farzad
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- 2023
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7. The impact of conventional smoking versus electronic cigarette on the expression of VEGF, PEMPA1, and PTEN in rat prostate
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Shabestari, Alireza Namazi, Tamehri Zadeh, Seyed Saeed, Zahmatkesh, Parisa, Baghdadabad, Leila Zareian, Mirzaei, Akram, Mashhadi, Rahil, Mesbah, Gholamreza, Khajavi, Alireza, Akbarzadehmoallemkolaei, Milad, Khoshchehreh, Mahdi, Rahimnia, Ramin, and Kazem Aghamir, Seyed Mohammad
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- 2023
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8. The Impact of Covid-19 Pandemic on Genitourinary Cancers Stage and Grade
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Taheri, Diana, Jahanshahi, Fatemeh, Khajavi, Alireza, Kafi, Fatemeh, Pouramini, Alireza, Farsani, Reza M., Alizadeh, Yasamin, Akbarzadeh, Maryam, Reis, Leonardo O., Khatami, Fatemeh, and Aghamir, Seyed Mohammad Kazem
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- 2023
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9. Hospital-acquired infections in a tertiary hospital in Iran before and during the COVID-19 pandemic
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Mohammadi, Abdolreza, Khatami, Fatemeh, Azimbeik, Zohreh, Khajavi, Alireza, Aloosh, Mehdi, and Aghamir, Seyed Mohammad Kazem
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- 2022
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10. Comparison of Tamsulosin and Tadalafil effects in LUTS treatment considering patients' atherosclerosis risk level
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Tavoosian, Ali, Reis, Leonardo Oliveira, Aluru, Pavan, Khajavi, Alireza, and Aghamir, Seyed Mohammad Kazem
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- 2022
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11. The correlation between promoter hypermethylation of VDR, CLDN, and CasR genes and recurrent stone formation
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Khatami, Fatemeh, Gorji, Alireza, Khoshchehreh, Mahdi, Mashhadi, Rahil, Pishkuhi, Mahin Ahmadi, Khajavi, Alireza, Shabestari, Alireza Namazi, and Aghamir, Seyed Mohammad Kazem
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- 2022
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12. Association of monocyte/high-density lipoprotein cholesterol ratio and the carotid intima-media thickness in diabetic patients
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Amouzegar, Atefeh, Mirzaasgari, Zahra, Mehrabi, Ali, Malek, Mojtaba, Alaei-Shahmiri, Fariba, Najafi, Laily, and Khajavi, Alireza
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- 2022
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13. Ambient Air Pollution and Incident Cardiovascular Disease in People With Type 2 Diabetes Mellitus: A Cohort Study.
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Khajavi, Alireza, Hashemi-Madani, Nahid, Hassanvand, Mohammad Sadegh, Naddafi, Kazem, and Khamseh, Mohammad E.
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Objectives: We aimed to assess the effect of air pollution on incident cardiovascular disease (CVD) in people with type 2 diabetesmellitus (T2DM). Methods: We tracked 486 T2DM patients from 2012 to 2021. Cox regression models were applied to assess the hazard of exposure to particulate matter, carbonmonoxide (CO), ozone, nitrogen dioxide, and sulfur dioxide (SO2) on incident CVD, revealing hazard ratios (HRs). Results: CVD incidents occurred in 73 individuals. Among men, each 1-ppm increase in CO levels raised the risk of CVD(HR: 2.66, 95%CI: 1.30-5.44). For women, a 5-ppb rise in SO2 increased CVD risk (HR: 1.60, 95%CI: 1.11-2.30). No notable impact of particulate pollutants was found. Conclusions: Persistent exposure to gaseous air pollutants, specifically CO and SO2, is linked to the development of CVD in men and women with T2DM. [ABSTRACT FROM AUTHOR]
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- 2024
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14. The Tsunami of COVID-19 Infection Among Kidney Transplant Recipients: A Single-Center Study from Iran
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Rahimzadeh, Hormat, Tamehri Zadeh, Seyed Saeed, Khajavi, Alireza, Saatchi, Mohammad, Reis, Leonardo Oliveira, Guitynavard, Fateme, Dehghani, Sanaz, Soleimani, Venus, and Aghamir, Seyed Mohammad Kazem
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- 2021
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15. Association of vitamin D receptor gene polymorphism with the occurrence of low bone density, osteopenia, and osteoporosis in patients with type 2 diabetes
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Ghodsi, Maryam, Keshtkar, Abbas Ali, Razi, Farideh, Mohammad Amoli, Mahsa, Nasli-Esfahani, Ensieh, Zarrabi, Fariba, Khashayar, Patricia, Khajavi, Alireza, Larijani, Bagher, and Mohajeri-Tehrani, Mohamad Reza
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- 2021
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16. Evaluation of the Effects of Opium on the Expression of SOX2 and OCT4 in Wistar Rat Bladder
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Menbari Oskouie, Iman, primary, Zareian Baghdadabad, Leila, additional, Mashhadi, Rahil, additional, Zahmatkesh, Parisa, additional, Mirzaei, Akram, additional, Khajavi, Alireza, additional, Noori, Maryam, additional, Mesbah, Gholamreza, additional, and Aghamir, Seyed Mohammad Kazem, additional
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- 2024
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17. The effect of GB21 acupressure on pain intensity in the first stage of labor in primiparous women: A randomized controlled trial
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Torkiyan, Hamideh, Sedigh Mobarakabadi, Sedigheh, Heshmat, Reza, Khajavi, Alireza, and Ozgoli, Giti
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- 2021
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18. Effects of the Surgical Ligation of the Ureter in Different Locations on the Kidney over Time in the Rat Model.
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Mohammadi, Abdolreza, Zareian Baghdadabad, Leila, Zahmatkesh, Parisa, Moradi Tabriz, Hedieh, Khajavi, Alireza, Mesbah, Gholamreza, Nikoofar, Parsa, Aghamir, Seyed Mohammad Kazem, and Gyftopoulos, Kostis
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LABORATORY rats ,URETERIC obstruction ,TUMOR necrosis factors ,ANIMAL disease models ,ANALYSIS of variance ,URETER diseases ,RENAL tubular transport disorders - Abstract
Purpose. To evaluate the effects of the surgical ligation of the ureter in different locations on the kidney over time in the rat model. Methods. A total of 155 rats were enrolled and randomly divided into the case (n = 150) and control (n = 5) groups. The case group included three separate groups (fifty rats in each group) that underwent surgical ureteral ligation at the proximal, middle, and distal ureter. The laboratory tests, and tumor necrosis factor α (TNF‐α), were measured in groups. The pathological evaluation for glomerular changes, tubular dilation, interstitial fibrosis, and interstitial infiltration of the inflammatory cells following the obstruction was performed (severity of tubular atrophy categorized too mild (+), moderate (++), and severe (+++)). To compare the continuous variables between the groups and between the measurement times, the analysis of variance (ANOVA) was used. Results. Our results revealed that the creatinine four weeks after the obstruction was significantly higher in the proximal group obstruction (p value: 0.046). The three groups had no significant differences regarding urine creatinine, serum sodium, and serum TNF (p value: 0.261). Obstruction did not change the glomerular morphology in three intervention groups after six weeks. The commencing of severe tubular atrophy in proximal, middle, and distal ureteral obstruction was at weeks three, four, and six, respectively. Conclusion. The location of ureteral obstruction is also crucial in deciding to intervene to relieve the complete ureteral obstruction. Severe tubular damage occurs in weeks three, four, and six in proximal, middle, and distal ureteral obstruction, respectively. [ABSTRACT FROM AUTHOR]
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- 2024
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19. Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS)
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Hariri, Sanam, Rahimi, Zahra, Hashemi-Madani, Nahid, Mard, Seyyed Ali, Hashemi, Farnaz, Mohammadi, Zahra, Danehchin, Leila, Abolnezhadian, Farhad, Valipour, Aliasghar, Paridar, Yousef, Mir-Nasseri, Mohammad Mahdi, Khajavi, Alireza, Masoudi, Sahar, Alvand, Saba, Cheraghian, Bahman, Shayesteh, Ali Akbar, Khamseh, Mohammad E., and Poustchi, Hossein
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- 2021
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20. Effects of Opium Consumption Regarding Age and Body Mass Index on Bladder Cancer's Grade and Stage.
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Farsani, Reza Mohammadi, Golmohammadi, Pedram, Pakdel, Alireza, Khajavi, Alireza, Cabrera, Victoria Sol, and Mohammadi, Abdolreza
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BODY mass index ,BLADDER cancer ,CHI-squared test ,TUMOR grading ,STATISTICAL software - Abstract
Introduction This paper aimed to evaluate the effect of opium on bladder cancer grade and stage. We analyzed the impact of opium on the stage and grade of bladder cancer. Methods In this retrospective study, we analyzed 446 patients with pathologically confirmed bladder cancer treated from February 2012 to January 2019. Demographic data including sex, age, body mass index, opium consumption, and smoking, were collected. Exclusion criteria were patients receiving chemotherapy, inaccessible pathologic reports, and previous abdominopelvic radiotherapy. Chi-squared test was used in case of categorical variables. The significance level was set at 0.05. The analyses were performed using the statistical software Stata ver. 13. Results Our results indicate show that higher muscle-invasive stages occurred in opium users group compared to the non-opium users (P-value<0.001 vs. P-value: 0.104). The BMIs≥25 indicated a greater high grades percentage in the opium users compared with non-users (P-values=0.137 and 0.316 for the ages <65 and ≥65 years and 0.602 and 0.013 for the BMIs <25 and ≥25). Accordingly, in people with BMIs≥25, odds of high grades were 2.8-fold, compared with non-users. Patients with BMIs of 25 or more had 2.8 times the chance of getting high grades compared to those who did not. Regarding muscle stages, while all subgroups showed significance, the largest effect size of 4.2 was obtained for the <65 age group. Conclusions Our data revealed the higher muscle-invasive stages in the opium users comparing compared to non-opium users. Also, in patients with BMIs≥25, odds of high grades were 2.8 folds, compared with non-opium users. [ABSTRACT FROM AUTHOR]
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- 2024
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21. Non-functioning pituitary macroadenoma: surgical outcomes, tumor regrowth, and alterations in pituitary function—3-year experience from the Iranian Pituitary Tumor Registry
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Najmaldin, Atousa, Malek, Mojtaba, Madani, Nahid Hashemi, Ghorbani, Mohammad, Akbari, Hamideh, Khajavi, Alireza, Qadikolaei, Omolbanin Asadi, and Khamseh, Mohammad Ebrahim
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- 2019
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22. Gestational diabetes mellitus: the correlation between umbilical coiling index, and intrapartum as well as neonatal outcomes
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Najafi, Laily, Abedini, Azadeh, Kadivar, Maryam, Khajavi, Alireza, Bordbar, Arash, Noohi, Amir Hussein, Mashak, Banafsheh, Hashemnejad, Maryam, Khamseh, Mohammad E., and Malek, Mojtaba
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- 2019
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23. Knowledge of physicians regarding the management of Type two Diabetes in a primary care setting: the impact of online continuous medical education
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Emami, Zahra, Kouhkan, Azam, Khajavi, Alireza, and Khamseh, Mohammad E.
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- 2020
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24. Impaired fasting glucose and major adverse cardiovascular events by hypertension and dyslipidemia status: the Golestan cohort study
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Hashemi Madani, Nahid, Ismail-Beigi, Faramarz, Poustchi, Hossein, Nalini, Mahdi, Sepanlou, Sadaf G., Malek, Mojtaba, Abbasi, Mohammad Amin, Khajavi, Alireza, Khamseh, Mohammad E., and Malekzadeh, Reza
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- 2020
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25. Birth seasonality in rural areas of Iran, analysis of 5,536,262 births from 1992 to 2007
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Khajavi, Alireza, Pishgar, Farhad, Parsaeian, Mahboubeh, Moghaddam, Sahar Saeedi, Jeddian, Alireza, Bahrami-Taghanaki, Hamid Reza, Jamshidi, Hamid Reza, and Naderimagham, Shohreh
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- 2016
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26. Evaluation of the Effects of Opium on the Expression of SOX2and OCT4in Wistar Rat Bladder
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Menbari Oskouie, Iman, Zareian Baghdadabad, Leila, Mashhadi, Rahil, Zahmatkesh, Parisa, Mirzaei, Akram, Khajavi, Alireza, Noori, Maryam, Mesbah, Gholamreza, and Aghamir, Seyed Mohammad Kazem
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Bladder cancer is a malignancy greatly affected by behavioral habits. The aim of this study was to examine the effect of opium on changes in the expression of OCT4and SOX2in the bladder tissue of rats. Thirty six rats were divided into six groups: 24 rats in the addicted group received morphine and opium for 4 months with 12 rats in the control group. Blood testing was done for the evaluation of CBC, MDA, and TAC. The bladder tissue was removed and checked by histopathological examination. All total RNA was extracted, then cDNAs were synthesized and the OCT4and SOX2gene expressions were evaluated by Real-time PCR. The OCT4mRNA expression level in the opium group of rats was significantly increased compared to the control group (13.5 and 6.8 fold in males and females respectively). Also, in the morphine group, similar augmentation was detected (3.8 and 6.7 fold in males and females respectively). The SOX2mRNA over-expression level was seen in the morphine group of both genders as compared to the control group (3.7 and 4.2 fold in male and female respectively) but in the opium group, enhancement of mRNA level was seen only in males (6.6 fold). Opium increases both OCT4and SOX2expression more than morphine in male rats, but in female rats, SOX2is increased more by morphine. Over expression of OCT4and SOX2was observed in rats treated with opium and morphine. Increased OCT4and SOX2expression was seen in opium-treated male rats, but in female rats, SOX2was increased more by morphine.
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- 2024
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27. Assisted conception as a potential prognostic factor predicting insulin therapy in pregnancies complicated by gestational diabetes mellitus
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Kouhkan, Azam, Baradaran, Hamid Reza, Hosseini, Roya, Arabipoor, Arezoo, Moini, Ashraf, Pirjani, Reihaneh, Khajavi, Alireza, and Khamseh, Mohammad E.
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- 2019
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28. Trends of Diabetes Mortality in Iran at National and Sub-National Levels from 1990 to 2015 and Its Association with Socioeconomic Factors
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Peykari, Niloofar, primary, Saeedi Moghaddam, Sahar, additional, Djalalini, Shirin, additional, Rezaei, Nazila, additional, Mansouri, Anita, additional, Naderimagham, Shohreh, additional, Mehdipour, Parinaz, additional, Pazhuheian, Forough, additional, Khajavi, Alireza, additional, Haghshenas, Rosa, additional, Mahmoudi, Negar, additional, Mahmoudi, Zohreh, additional, Dilmaghani-Marand, Arezou, additional, Rezaee, Kamyar, additional, Larijani, Bagher, additional, Khosravi, Ardeshir, additional, and Farzadfar, Farshad, additional
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- 2022
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29. Comparison Between Percutaneous Nephrolithotomy and Retrograde Flexible Nephrolithotripsy in Obese Patients with 2 - 4 cm Renal Stones
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Hamidi, Morteza, primary, Tamehri Zadeh, Seyed Saeed, additional, Samadi, Ali, additional, Namdari, Farshad, additional, Khajavi, Alireza, additional, Fakhr Yasseri, Alimohammad, additional, and Aghamir, Seyed Mohammad Kazem, additional
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- 2022
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30. Metabolic effects of dopamine-agonists treatment among patients with prolactinomas
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Kabootari, Maryam, primary, Shirmohammadli, Habibeh, additional, Golgiri, Fatemeh, additional, Mosalamiaghili, Seyedarad, additional, Khajavi, Alireza, additional, and Akbari, Hamideh, additional
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- 2022
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31. The association of umbilical coiling and angiogenesis markers: Impact assessment of gestational diabetes
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Najafi, Laily, primary, Honardoost, Maryam, additional, Khajavi, Alireza, additional, Cheraghi, Sara, additional, Kadivar, Maryam, additional, and Khamseh, Mohammad E., additional
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- 2022
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32. Hs-CRP and TNF-α effects on postnatal umbilical coiling: impact assessment of the gestational diabetes mellitus in a prospective cohort study
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Akbari, Hamideh, primary, Monemi, Fateme, additional, Notej, Atefe, additional, Khajavi, Alireza, additional, Ghadikolaei, Omolbanin Asadi, additional, Abdolmaleki, Fereshte, additional, and Najafi, Laily, additional
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- 2022
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33. The impact of long-term exposure to PM10, SO2, O3, NO2, and CO on incident dysglycemia: a population-based cohort study
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Tamehri Zadeh, Seyed Saeed, primary, Khajavi, Alireza, additional, Ramezankhani, Azra, additional, Azizi, Fereidoun, additional, and Hadaegh, Farzad, additional
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- 2022
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34. Association between Poor Sleep Quality with Anxiety and Depression Scores among Patients with Urological Cancers
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Arya, Pantea, primary, Ahadi, Zeinab, additional, Khajavi, Alireza, additional, Tamehri Zadeh, Seyed Saeed, additional, Pourhosein, Elahe, additional, and Aghamir, Seyed Mohammad Kazem, additional
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- 2022
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35. Comorbidities Associated with Complicated Hospital Course and Death in COVID-19 Patients: A Retrospective Study from Iran
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Tavakoli, Nader, primary, Hashemi-Madani, Nahid, additional, Malek, Mojtaba, additional, Emami, Zahra, additional, Khajavi, Alireza, additional, Aghili, Rokhsareh, additional, Honardoost, Maryam, additional, Abdolmaleki, Fereshteh, additional, and Khamseh, Mohammad Ebrahim, additional
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- 2021
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36. Cardiovascular Events in People With Type 2 Diabetes: Performance of Framingham, UKPDS, and ADVANCE Risk Equations
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Yaghoubvand, Elaheh, primary, Aghili, Rokhsareh, additional, Khajavi, Alireza, additional, and Khamseh, Mohammad Ebrahim, additional
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- 2021
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37. Gestational diabetes mellitus: Major risk factors and pregnancy-related outcomes: A cohort study
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Kouhkan, Azam, primary, Najafi, Laily, additional, Malek, Mojtaba, additional, Reza Baradaran, Hamid, additional, Hosseini, Roya, additional, Khajavi, Alireza, additional, and Ebrahim Khamseh, Mohammad, additional
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- 2021
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38. Assessment of Serum and Urine Neurophil Gelatinase- Associated Lipocalin (s-NGAL and u-NGAL) Level as a Predictive Factor of Disease Progression in Diabetic Nephropathy in Type 2 DM
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Amouzegar, Atefeh, primary, Najafi, Laily, additional, Keshtkar Rajabi, Shahin, additional, Pirsaheb, Sondos, additional, Keyvani, Hossein, additional, Khajavi, Alireza, additional, Shati, Mohsen, additional, and Hadavand, Fahimeh, additional
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- 2021
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39. Post-treatment heterogeneity of cardiometabolic risk in patients with acromegaly: The impact of GH and IGF-1
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Heydari, Mahshid, primary, Hashemi-Madani, Nahid, additional, Emami, Zahra, additional, Khajavi, Alireza, additional, Ghorbani, Mohammad, additional, Malek, Mojtaba, additional, Ataei Kachuee, Manizhe, additional, and Khamseh, Mohammad E., additional
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- 2021
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40. Impact of short- and long-term exposure to air pollution on blood pressure: A two-decade population-based study in Tehran
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Khajavi, Alireza, primary, Tamehri Zadeh, Seyed Saeed, additional, Azizi, Fereidoun, additional, Brook, Robert D., additional, Abdi, Hengameh, additional, Zayeri, Farid, additional, and Hadaegh, Farzad, additional
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- 2021
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41. Additional file 1 of Prevalence and determinants of diabetes and prediabetes in southwestern Iran: the Khuzestan comprehensive health study (KCHS)
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Hariri, Sanam, Rahimi, Zahra, Hashemi-Madani, Nahid, Mard, Seyyed Ali, Hashemi, Farnaz, Mohammadi, Zahra, Danehchin, Leila, Abolnezhadian, Farhad, Valipour, Aliasghar, Paridar, Yousef, Mir-Nasseri, Mohammad Mahdi, Khajavi, Alireza, Masoudi, Sahar, Alvand, Saba, Cheraghian, Bahman, Shayesteh, Ali Akbar, Khamseh, Mohammad E., and Poustchi, Hossein
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Additional file 1: Supplementary table. Distribution of people who were diagnosed with diabetes in the Khuzestan Comprehensive Health Study (KCHS), n = 4673
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- 2021
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42. Age and aging effects on blood pressure: 15 years follow‐up of Tehran lipid and glucose study
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Khajavi, Alireza, primary, Zayeri, Farid, additional, Ramezankhani, Azra, additional, Nazari, Amir, additional, Azizi, Fereidoun, additional, and Hadaegh, Farzad, additional
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- 2021
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43. Obesity and incident gastrointestinal cancers: overall body size or central obesity measures, which factor matters?
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Hashemi Madani, Nahid, primary, Etemadi, Arash, additional, Nalini, Mahdi, additional, Poustchi, Hossein, additional, Khajavi, Alireza, additional, Mirzazade, Elahe, additional, Mirfakhraei, Hosna, additional, Pourshams, Akram, additional, Khoshnia, Masoud, additional, Gharavi, Abdolsamad, additional, Merat, Shahin, additional, Khamseh, Moahammad E., additional, and Malekzadeh, Reza, additional
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- 2021
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44. Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017
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Lozano, Rafael, Fullman, Nancy, Abate, Degu, Abay, Solomon M, Abbafati, Cristiana, Abbasi, Nooshin, Abbastabar, Hedayat, Abd-Allah, Foad, Abdela, Jemal, Abdelalim, Ahmed, Abdel-Rahman, Omar, Abdi, Alireza, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Nebiyu Dereje, Abebe, Zegeye, Abejie, Ayenew Negesse, Abera, Semaw F, Abil, Olifan Zewdie, Aboyans, Victor, Abraha, Haftom Niguse, Abrham, Aklilu Roba, Abu-Raddad, Laith Jamal, Abu-Rmeileh, Niveen Me, Abyu, Gebre Y, Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Acharya, Pawan, Adamu, Abdu A, Adebayo, Oladimeji M, Adedeji, Isaac Akinkunmi, Adedoyin, Rufus Adesoji, Adekanmbi, Victor, Adetokunboh, Olatunji O, Adhena, Beyene Meressa, Adhikari, Tara Ballav, Adib, Mina G, Adou, Arsène Kouablan, Adsuar, Jose C, Afarideh, Mohsen, Afshari, Mahdi, Afshin, Ashkan, Agarwal, Gina, Aghayan, Sargis Aghasi, Agius, Dominic, Agrawal, Anurag, Agrawal, Sutapa, Ahmadi, Alireza, Ahmadi, Mehdi, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Ahmed, Sayem, Akalu, Temesgen Yihunie, Akanda, Ali S, Akbari, Mohammad Esmaeil, Akibu, Mohammed, Akinyemi, Rufus Olusola, Akinyemiju, Tomi, Akseer, Nadia, Alahdab, Fares, Al-Aly, Ziyad, Alam, Khurshid, Alam, Tahiya, Albujeer, Ammar, Alebel, Animut, Alene, Kefyalew Addis, Al-Eyadhy, Ayman, Alhabib, Samia, Ali, Raghib, Alijanzadeh, Mehran, Alizadeh-Navaei, Reza, Aljunid, Syed Mohamed, Alkerwi, Ala'a, Alla, François, Allebeck, Peter, Allen, Christine A, Almasi, Ali, Al-Maskari, Fatma, Al-Mekhlafi, Hesham M, Alonso, Jordi, Al-Raddadi, Rajaa M, Alsharif, Ubai, Altirkawi, Khalid, Alvis-Guzman, Nelson, Amare, Azmeraw T, Amenu, Kebede, Amini, Erfan, Ammar, Walid, Anber, Nahla Hamed, Anderson, Jason A, Andrei, Catalina Liliana, Androudi, Sofia, Animut, Megbaru Debalkie, Anjomshoa, Mina, Ansari, Hossein, Ansariadi, Ansariadi, Ansha, Mustafa Geleto, Antonio, Carl Abelardo T, Anwari, Palwasha, Appiah, Lambert Tetteh, Aremu, Olatunde, Areri, Habtamu Abera, Ärnlöv, Johan, Arora, Monika, Aryal, 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Zamani, M, Zare, Z, Zavala-Arciniega, L, Zegeye, Dt, Zegeye, Ea, Zeleke, Aj, Zendehdel, K, Zerfu, Ta, Zhang, Al, Zhang, X, Zhou, M, Zhu, J, Zimsen, Srm, Zodpey, S, Zoeckler, L, Zucker, I, Zuhlke, Ljj, Lim, S, and Murray, Cjl.
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GENDER-DIFFERENCES ,SUICIDE ,Medicine (all) ,Burden of Disease Study 2017 ,SDG ,CONSUMPTION ,11 Medical And Health Sciences ,GBD, Sustainable Development Goals ,PREVENTION ,ALCOHOL-USE ,CARDIOVASCULAR-DISEASE ,SMOKING PREVALENCE ,General & Internal Medicine ,factors risk ,Medicine and Health Sciences ,Human medicine ,CESSATION ,PERSPECTIVE ,TRANSITION - Abstract
Background Efforts to establish the 2015 baseline and monitor early implementation of the UN Sustainable Development Goals (SDGs) highlight both great potential for and threats to improving health by 2030. To fully deliver on the SDG aim of "leaving no one behind", it is increasingly important to examine the health-related SDGs beyond national-level estimates. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017), we measured progress on 41 of 52 health -related SDG indicators and estimated the health-related SDG index for 195 countries and territories for the period 1990-2017, projected indicators to 2030, and analysed global attainment. Methods We measured progress on 41 health-related S DG indicators from 1990 to 2017, an increase of four indicators since GBD 2016 (new indicators were health worker density, sexual violence by non-intimate partners, population census status, and prevalence of physical and sexual violence [reported separately]). We also improved the measurement of several previously reported indicators. We constructed national-level estimates and, for a subset of health-related SDGs, examined indicator-level differences by sex and Socio-demographic Index (SDI) quintile. We also did subnational assessments of performance for selected countries. To construct the health related SDG index, we transformed the value for each indicator on a scale of 0-100, with 0 as the 2.5th percentile and 100 as the 97.5th percentile of 1000 draws calculated from 1990 to 2030, and took the geometric mean of the scaled indicators by target. To generate projections through 2030, we used a forecasting framework that drew estimates from the broader GBD study and used weighted averages of indicator-specific and country-specific annualised rates of change from 1990 to 2017 to inform future estimates. We assessed attainment of indicators with defined targets in two ways: first, using mean values projected for 2030, and then using the probability of attainment in 2030 calculated from 1000 draws. We also did a global attainment analysis of the feasibility of attaining SDG targets on the basis of past trends. Using 2015 global averages of indicators with defined SDG targets, we calculated the global annualised rates of change required from 2015 to 2030 to meet these targets, and then identified in what percentiles the required global annualised rates of change fell in the distribution of country-level rates of change from 1990 to 2015. We took the mean of these global percentile values across indicators and applied the past rate of change at this mean global percentile to all health-related SDG indicators, irrespective of target definition, to estimate the equivalent 2030 global average value and percentage change from 2015 to 2030 for each indicator. Findings The global median health-related SDG index in 2017 was 59.4 (IQR 35.4-67.3), ranging from a low of 11.6 (95% uncertainty interval 9.6-14.0) to a high of 84.9 (83.1-86.7). SDG index values in countries assessed at the subnational level varied substantially particularly in China and India, although scores in Japan and the UK were more homogeneous. Indicators also varied by SDI quintile and sex, with males having worse outcomes than females for non-communicable disease (NCD) mortality, alcohol use, and smoking, among others. Most countries were projected to have a higher health-related SDG index in 2030 than in 2017, while country-level probabilities of attainment by 2030 varied widely by indicator. Under-5 mortality, neonatal mortality, maternal mortality ratio, and malaria indicators had the most countries with at least 95% probability of target attainment. Other indicators, including NCD mortality and suicide mortality, had no countries projected to meet corresponding SDG targets on the basis of projected mean values for 2030 but showed some probability of attaimnent by 2030. For some indicators, including child malnutrition, several infectious diseases, and most violence measures, the annualised rates of change required to meet SDG targets far exceeded the pace of progress achieved by any country in the recent past. We found that applying the mean global annualised rate of change to indicators without defined targets would equate to about 19% and 22% reductions in global smoking and alcohol consumption, respectively; a 47% decline in adolescent birth rates; and a more than 85% increase in health worker density per 1000 population by 2030. Interpretation The GBD study offers a unique, robust platform for monitoring the health -related SDGs across demographic and geographic dimensions. Our findings underscore the importance of increased collection and analysis of disaggregated data and highlight where more deliberate design or targeting of interventions could accelerate progress in attaining the SDGs. Current projections show that many health -related SDG indicators, NCDs, NCD-related risks, and violence -related indicators will require a concerted shift away from what might have driven past gains curative interventions in the case of NCDs towards multisectoral, prevention -oriented policy action and investments to achieve SDG aims. Notably, several targets, if they are to be met by 2030, demand a pace of progress that no country has achieved in the recent past. The future is fundamentally uncertain, and no model can fully predict what breakthroughs or events might alter the course of the S DGs. What is clear is that our actions or inaction today will ultimately dictate how close the world, collectively, can get to leaving no one behind by 2030. Copyright (C) 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
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45. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017
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Roth, Gregory A., Collaborotors, G. B. 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Jc, Ferrari, Aj, Feyissa, Gt, Foigt, Na, Foreman, Kj, Frank, Td, Fuller, Je, Fürst, T, Furtado, Jm, Futran, Nd, Garcia-Basteiro, Al, Garcia-Gordillo, Ma, Gardner, Wm, Gebre, Ak, Gebrehiwot, Tt, Gebremedhin, At, Gebremichael, Tg, Gelano, Tf, Geleijnse, Jm, Geramo, Ycd, Gething, Pw, Gezae, Ke, Ghadami, Mr, Gibney, Kb, Gill, Tk, Gillum, Rf, Ginawi, Ia, Goldberg, Em, Gómez-Dantés, H, Gona, Pn, Gopalani, Sv, Gorman, Tm, Goulart, Ac, Gnedovskaya, Ev, Gugnani, Hc, Guimaraes, Al, Gupta, Pc, Gutiérrez, Ra, Haagsma, Ja, Hagos, Tb, Hailegiyorgis, Tt, Hailu, Gb, Hamadeh, Rr, Handal, Aj, Hankey, Gj, Harb, Hl, Haro, Jm, Hassen, Hy, Hay, Rj, Hay, Si, Hegazy, Mi, Henry, Nj, Hibstu, Dt, Hoek, Hw, Hole, Mk, Hosgood, Hd, Hosseini, Sm, Hotez, Pj, Hoy, Dg, Huang, Jj, Hussen, Mm, Irvani, Ssn, Irvine, Cm, Islam, Sm, Jacobsen, Kh, Jain, Sk, Jalu, Mt, James, Sl, Jayatilleke, Au, Jenkins, Kj, Jha, Rp, Johnson, Co, Johnson, Sc, Jonas, Jb, Jozwiak, Jj, Jungari, Sb, Jürisson, M, Kassa, Dh, Kassa, Gm, Kassa, Td, Kassebaum, Nj, Katikireddi, Sv, Karyani, Ak, Kefale, At, Keiyoro, Pn, Kemp, Gr, Kengne, Ap, Kesavachandran, Cn, Khafaie, Ma, Khalil, Ia, Khan, Ea, Khan, Ma, Khang, Yh, Khater, Mm, Khoja, At, Khosravi, Mh, Kiadaliri, Aa, Kibret, Gd, Kidanemariam, Zt, Kiirithio, Dn, Kim, Ye, Kim, Yj, Kimokoti, Rw, Kivimäki, M, Knudsen, Ak, Kocarnik, Jm, Kopec, Ja, Koul, Pa, Kravchenko, Ma, Kumar, Ga, Kutz, Mj, Kyu, Hh, Lad, Dp, Lad, Sd, Lal, Dk, Lam, Jo, Lami, Fh, Lansingh, Vc, Larson, Hj, Lau, Km, Lazarus, Jv, Lee, Ph, Leshargie, Ct, Lim, Ll, Limenih, Ma, Lopez, Ad, Lotufo, Pa, Macarayan, Erk, Mackay, Mt, Maclachlan, Jh, Maddison, Er, Maghavani, Dp, Malta, Dc, Manda, Al, Mandarano-Filho, Lg, Mansournia, Ma, Mapoma, Cc, Maravilla, Jc, Marks, Gb, Martins-Melo, Fr, März, W, Marzan, Mb, Masci, Jr, Massenburg, Bb, Mathur, Mr, Maulik, Pk, Mcgrath, Jj, Mcmahon, Bj, Mehndiratta, Mm, Mehta, Km, Mekonnen, Tc, Memiah, Ptn, Memish, Za, Mengistu, Dt, Mensah, Ga, Mereta, St, Meretoja, Tj, Mezgebe, Hb, Millear, Ai, Miller, Tr, Miller-Petrie, Mk, Mini, Gk, Mirrakhimov, Em, Misganaw, At, Mohammad, Ka, Mohammed, Ma, Mokdad, Ah, Moreno Velásquez, I, Morrison, Sd, Moschos, Mm, Mousavi, Sm, Muchie, Kf, Mueller, Uo, Mumford, Je, Musa, Ki, Nachega, Jb, Nansseu, Jr, Nascimento, Br, Negoi, Ri, Newton, Crj, Ngalesoni, Fn, Ngunjiri, Jw, Nguyen, Aq, Nguyen, Ht, Nguyen, Lh, Nguyen, Th, Ningrum, Dna, Nirayo, Yl, Nixon, Mr, Norheim, Of, Noubiap, Jj, Nouri, Hr, Nourollahpour Shiadeh, M, Nowroozi, Mr, Odell, Cm, Ogbo, Fa, Oh, Ih, Olagunju, At, Olivares, Pr, Olsen, He, Olusanya, Bo, Olusanya, Jo, Ong, Kl, Ong, Sk, Orpana, Hm, Ortiz, Jr, Øverland, S, Owolabi, Mo, Özdemir, R, P A, M, Pakhare, Ap, Pakpour, Ah, Pandian, Jd, Park, Ek, Parry, Cdh, Patton, Gc, Paturi, Vr, Paulson, Kr, Pereira, Dm, Phillips, Mr, Piel, Fb, Pigott, Dm, Pillay, Jd, Postma, Mj, Purcell, Ca, Quistberg, Da, Rade, Kw, Radfar, A, Rafay, A, Rafiei, A, Rahim, F, Rahman, Mhu, Rahman, Ma, Rai, Rk, Ranabhat, Cl, Rao, Pc, Rawaf, Dl, Razo-García, C, Reiner, Rc, Reitsma, Mb, Renzaho, Amn, Riahi, Sm, Ribeiro, Alp, Rios-Blancas, Mj, Roba, Kt, Roberts, Nl, Robinson, Sr, Sahraian, Ma, Saldanha, Rf, Sambala, Ez, Samy, Am, Sanchez-Niño, Md, Santomauro, Df, Santos, Jv, Milicevic, Mm, Sao Jose, Bp, Sarker, Ar, Sarmiento-Suárez, R, Sawant, Ar, Schmidt, Mi, Schneider, Ijc, Schöttker, B, Schutte, Ae, Schwebel, Dc, Scott, Jg, Sepanlou, Sg, Serván-Mori, E, Shackelford, Ka, Shaheen, Aa, Shaikh, Ma, Shrime, Mg, Siddiqi, Tj, Sigfusdottir, Id, Silberberg, Dh, Silva, Da, Silva, Jp, Silva, Ntd, Silveira, Dga, Singh, Ja, Singh, Np, Singh, Pk, Sinha, Dn, Sobaih, Bh, Sorensen, Rjd, Soriano, Jb, Soyiri, In, Sposato, La, Sreeramareddy, Ct, Stanaway, Jd, Starodubov, Vi, Stein, Dj, Stewart, Lg, Stokes, Ma, Subart, Ml, Sufiyan, Mb, Sur, Pj, Sykes, Bl, Sylaja, Pn, Sylte, Do, Szoeke, Cei, Tabarés-Seisdedos, R, Tadakamadla, Sk, Tassew, Sg, Tekalign, Tg, Tekle, Mg, Temsah, Mh, Teshale, My, Tessema, Ga, Thankappan, Kr, Thrift, Ag, Thurston, Gd, To, Qg, Torre, Ae, Tortajada-Girbés, M, Tovani-Palone, Mr, Tran, Bx, Tran, Kb, Troeger, Ce, Truelsen, Tc, Truong, Nt, Tsadik, Ag, Tuzcu, Em, Ukwaja, Kn, Undurraga, Ea, Updike, Rl, Uthman, Oa, Uzun, Sb, Valdez, Pr, Vasankari, Tj, Vladimirov, Sk, Vollset, Se, Wagner, Gr, Wallin, Mt, Walson, Jl, Wang, Yp, Wassie, Mm, Weintraub, Rg, Weldegwergs, Kg, Werkneh, Aa, West, Te, Whiteford, Ha, Wilner, Lb, Wolfe, Cda, Wu, Yc, Wyper, Gma, Yahyazadeh Jabbari, Sh, Yan, Ll, Yasin, Yj, Yentür, Gk, Yimer, Em, Yirsaw, Bd, Yoon, Sj, Younis, Mz, Zaman, Sb, Zeleke, Aj, Zenebe, Zm, Zhang, Al, Zuhlke, Lj, and Murray, Cjl.
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Adult ,Male ,Adolescent ,national age-sex-specific mortality ,UNITED-STATES ,Global Health ,Socioeconomic Factor ,Global Burden of Disease ,GBD, causes of death ,Young Adult ,Age Distribution ,Life Expectancy ,General & Internal Medicine ,Cause of Death ,PUBLIC-HEALTH PROBLEM ,mortality ,282 causes global burden of disease ,Sex Distribution ,Child ,Aged ,Aged, 80 and over ,BARRIERS ,DEMENTIA ,Medicine (all) ,Infant, Newborn ,Infant ,11 Medical And Health Sciences ,Middle Aged ,TRENDS ,PREVENTION ,PREVALENCE ,ALZHEIMERS-DISEASE ,INDIVIDUALS ,3121 General medicine, internal medicine and other clinical medicine ,Child, Preschool ,REGISTRATION ,Female ,Human medicine ,Human - Abstract
Background Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD 2017 provides a comprehensive assessment of cause-specific mortality for 282 causes in 195 countries and territories from 1980 to 2017. Methods The causes of death database is composed of vital registration (VR), verbal autopsy (VA), registry, survey, police, and surveillance data. GBD 2017 added ten VA studies, 127 country-years of VR data, 502 cancer-registry country-years, and an additional surveillance country-year. Expansions of the GBD cause of death hierarchy resulted in 18 additional causes estimated for GBD 2017. Newly available data led to subnational estimates for five additional countries Ethiopia, Iran, New Zealand, Norway, and Russia. Deaths assigned International Classification of Diseases (ICD) codes for non-specific, implausible, or intermediate causes of death were reassigned to underlying causes by redistribution algorithms that were incorporated into uncertainty estimation. We used statistical modelling tools developed for GBD, including the Cause of Death Ensemble model (CODErn), to generate cause fractions and cause specific death rates for each location, year, age, and sex. Instead of using UN estimates as in previous versions, GBD 2017 independently estimated population size and fertility rate for all locations. Years of life lost (YLLs) were then calculated as the sum of each death multiplied by the standard life expectancy at each age. All rates reported here are age-standardised. Findings At the broadest grouping of causes of death (Level 1), non-communicable diseases (NC Ds) comprised the greatest fraction of deaths, contributing to 73.4% (95% uncertainty interval [UI] 72.5-74.1) of total deaths in 2017, while communicable, maternal, neonatal, and nutritional (CMNN) causes accounted for 186% (17.9-19.6), and injuries 8.0% (7.7-8.2). Total numbers of deaths from NCD causes increased from 2007 to 2017 by 22.7% (21.5-23.9), representing an additional 7.61 million (7. 20-8.01) deaths estimated in 2017 versus 2007. The death rate from NCDs decreased globally by 7.9% (7.08.8). The number of deaths for CMNN causes decreased by 222% (20.0-24.0) and the death rate by 31.8% (30.1-33.3). Total deaths from injuries increased by 2.3% (0-5-4-0) between 2007 and 2017, and the death rate from injuries decreased by 13.7% (12.2-15.1) to 57.9 deaths (55.9-59.2) per 100 000 in 2017. Deaths from substance use disorders also increased, rising from 284 000 deaths (268 000-289 000) globally in 2007 to 352 000 (334 000-363 000) in 2017. Between 2007 and 2017, total deaths from conflict and terrorism increased by 118.0% (88.8-148.6). A greater reduction in total deaths and death rates was observed for some CMNN causes among children younger than 5 years than for older adults, such as a 36.4% (32.2-40.6) reduction in deaths from lower respiratory infections for children younger than 5 years compared with a 33.6% (31.2-36.1) increase in adults older than 70 years. Globally, the number of deaths was greater for men than for women at most ages in 2017, except at ages older than 85 years. Trends in global YLLs reflect an epidemiological transition, with decreases in total YLLs from enteric infections, respirator}, infections and tuberculosis, and maternal and neonatal disorders between 1990 and 2017; these were generally greater in magnitude at the lowest levels of the Socio-demographic Index (SDI). At the same time, there were large increases in YLLs from neoplasms and cardiovascular diseases. YLL rates decreased across the five leading Level 2 causes in all SDI quintiles. The leading causes of YLLs in 1990 neonatal disorders, lower respiratory infections, and diarrhoeal diseases were ranked second, fourth, and fifth, in 2017. Meanwhile, estimated YLLs increased for ischaemic heart disease (ranked first in 2017) and stroke (ranked third), even though YLL rates decreased. Population growth contributed to increased total deaths across the 20 leading Level 2 causes of mortality between 2007 and 2017. Decreases in the cause-specific mortality rate reduced the effect of population growth for all but three causes: substance use disorders, neurological disorders, and skin and subcutaneous diseases. Interpretation Improvements in global health have been unevenly distributed among populations. Deaths due to injuries, substance use disorders, armed conflict and terrorism, neoplasms, and cardiovascular disease are expanding threats to global health. For causes of death such as lower respiratory and enteric infections, more rapid progress occurred for children than for the oldest adults, and there is continuing disparity in mortality rates by sex across age groups. Reductions in the death rate of some common diseases are themselves slowing or have ceased, primarily for NCDs, and the death rate for selected causes has increased in the past decade. Copyright (C) 2018 The Author(s). Published by Elsevier Ltd.
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- 2018
46. Prevalence and Determinants of Diabetes and Prediabetes in Southwestern Iran: The Khuzestan Comprehensive Health Study (KCHS)
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Hariri, Sanam, primary, Rahimi, Zahra, additional, Madani, Nahid Hashemi, additional, Mard, Seyyed Ali, additional, Hashemi, Farnaz, additional, Mohammadi, Zahra, additional, Danehchin, Leila, additional, Abolnezhadian, Farhad, additional, Valipour, Aliasghar, additional, Paridar, Yousef, additional, Mir-Nasseri, Mohammad Mahdi, additional, Khajavi, Alireza, additional, Masoudi, Sahar, additional, Alvand, Saba, additional, Cheraghian, Bahman, additional, Shayesteh, Ali Akbar, additional, Khamseh, Mohammad E., additional, and Poustchi, Hossein, additional
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- 2021
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47. Human resources for health density and its associations with child and maternal mortality in the Islamic Republic of Iran
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Madad, Zahra, primary, Pishgar, Farhad, additional, Ghasemi, Erfan, additional, Khajavi, Alireza, additional, Moghaddam, Sahar, additional, and Farzadfar, Farshad, additional
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- 2021
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48. The effect of treatment duration on metabolic parameters in patients with prolactinoma: A prospective longitudinal study
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Imani, Mehrnaz, primary, Abbasi, Rowshanak, additional, Golgiri, Fatemeh, additional, Khajavi, Alireza, additional, and Akbari, Hamideh, additional
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- 2021
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49. Post-treatment heterogeneity of cardiometabolic risk in patients with acromegaly: The impact of GH and IGF-1.
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Heydari, Mahshid, Hashemi-Madani, Nahid, Emami, Zahra, Khajavi, Alireza, Ghorbani, Mohammad, Malek, Mojtaba, Ataei Kachuee, Manizhe, and Khamseh, Mohammad E.
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SOMATOMEDIN C ,BODY mass index ,MAGNETIC resonance imaging ,ACROMEGALY ,WAIST-hip ratio ,DIASTOLIC blood pressure - Abstract
Metabolic abnormalities are frequently seen in patients with acromegaly. However, it is not clear to what extent growth hormone/insulin-like growth factor-1 (GH/IGF-1) contributes to the development of these abnormalities. This study aimed to explore the impact of postoperative GH/IGF–1 on different aspects of metabolic abnormalities in patients with acromegaly. This retrospective, registry-based study conducted on 102 patients with acromegaly. The impact of GH/IGF-1 on the cardiometabolic risk factors at 3–12 months after surgery has been investigated using linear and logistic regression models. In this study, each 1 ng/ml increase in the level of GH was significantly associated with a 2 mg/dl increase in the level of fasting blood glucose (FBG), a 0.5 mmHg increase in the level of systolic blood pressure (SBP), and a 0.9 mmHg increase in the level of diastolic blood pressure (DBP). Upon multivariate analysis, GH, but not IGF-1, significantly increased the odds of diabetes mellitus (DM) (OR; 1.2, 95% CI; 1.0–1.4, p =.025). Our findings indicated at early postoperative stage, GH is significantly associated with the levels of FBG, SBP, and DBP. Moreover, GH, but not IGF-1, appears as a predictive factor for the presence of DM. However, neither GH nor IGF-1 could predict the presence of hypertension HTN, or dyslipidemia in this study. CVD: Cardiovascular disease; GH: Growth hormone; IGF-1: Insulin-like growth factor 1; BMI: Body mass index; HTN: hypertension; IPTR: Iran Pituitary Tumor Registry; WC: Waist circumference; MRI: Magnetic resonance imaging; FBG: Fasting blood glucose; HbA1C: Glycated hemoglobin; TG: Triglyceride; LDL: Low density lipoprotein; HDL: High density lipoprotein; SBP: Systolic blood pressure; DBP: Diastolic blood pressure [ABSTRACT FROM AUTHOR]
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- 2022
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50. Post-treatment heterogeneity of cardio-metabolic risk in acromegalic patients: The Impacts of GH and IGF-1
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Heydari, Mahshid, primary, Madani, Nahid Hashemi, additional, Emami, Zahra, additional, Khajavi, Alireza, additional, Ghorbani, Mohammad, additional, Malek, Mojtaba, additional, Kachuee, Manizhe Ataei, additional, and Khamseh, Mohammad, additional
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- 2020
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