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275 results on '"Ketelsen, D."'

12. Three-Year Sustained Clinical Efficacy of Drug-Coated Balloon Angioplasty in a Real-World Femoropopliteal Cohort

Author

Torsello, G., Stavroulakis, K., Brodmann, M., Micari, A., Tepe, G., Veroux, P., Benko, A., Choi, D., Vermassen, F. E. G., Jaff, M. R., Guo, J., Dobranszki, R., Zeller, T., Peeters, P., Scheinert, D., Bosiers, M., Maene, L., Do, D. -D., Hendriks, J., Keirse, K., Merkely, B., Lardenoije, J. -W., Ruzsa, Z., Vogel, B., Albuquerque e Castro, J., Periard, D., Ludyga, T., Midy, D., Lansink, W., Ketelsen, D., Dubenec, S., Banyai, M., Chakfe, N., Xaver Roithinger, F., Trani, Carlo, Mansour, H., Rha, S. -W., Vermassen, F., Belenky, A., Spak, L., Chalmers, N., Kum, S., Won, J. H., Vozar, M., Teng Tan, K., Labib, M., Borst, G. -J. D., Do, Y. -S., Teijink, J., Gomez, J. F., Falkowski, A., Ferreira, L., Matela, J., Lee, S. -W., Verhoeven, B., Mannheim, D., Nessi, F., Vulev, I., Vries, J. -P. D., Maly, R., Kavteladze, Z., Turner, D., Mendiz, O., Kolvenbach, R., Karnabatidis, D., Cuellar, C., Venermo, M., Velicka, L., Lundberg, G., Trani C. (ORCID:0000-0001-9777-013X), Torsello, G., Stavroulakis, K., Brodmann, M., Micari, A., Tepe, G., Veroux, P., Benko, A., Choi, D., Vermassen, F. E. G., Jaff, M. R., Guo, J., Dobranszki, R., Zeller, T., Peeters, P., Scheinert, D., Bosiers, M., Maene, L., Do, D. -D., Hendriks, J., Keirse, K., Merkely, B., Lardenoije, J. -W., Ruzsa, Z., Vogel, B., Albuquerque e Castro, J., Periard, D., Ludyga, T., Midy, D., Lansink, W., Ketelsen, D., Dubenec, S., Banyai, M., Chakfe, N., Xaver Roithinger, F., Trani, Carlo, Mansour, H., Rha, S. -W., Vermassen, F., Belenky, A., Spak, L., Chalmers, N., Kum, S., Won, J. H., Vozar, M., Teng Tan, K., Labib, M., Borst, G. -J. D., Do, Y. -S., Teijink, J., Gomez, J. F., Falkowski, A., Ferreira, L., Matela, J., Lee, S. -W., Verhoeven, B., Mannheim, D., Nessi, F., Vulev, I., Vries, J. -P. D., Maly, R., Kavteladze, Z., Turner, D., Mendiz, O., Kolvenbach, R., Karnabatidis, D., Cuellar, C., Venermo, M., Velicka, L., Lundberg, G., and Trani C. (ORCID:0000-0001-9777-013X)

Abstract

Purpose: To report the 36-month outcomes from the prospective, multicenter, single-arm IN.PACT Global Study (ClinicalTrials.gov identifier NCT01609296) evaluating the performance of the IN.PACT Admiral drug-coated balloon (DCB) in real-world patients with femoropopliteal occlusive disease. Materials and Methods: The IN.PACT Global Study was conducted at 64 international sites and enrolled 1535 patients with complex lesions, which included bilateral disease, multiple lesions, de novo in-stent restenosis, long lesions, and chronic total occlusions. The predefined full clinical cohort included 1406 patients (mean age 68.6 years; 67.8% men) with claudication or rest pain treated with the study DCB. Mean lesion length was 12.09±9.54 cm; 18.0% had in-stent restenosis, 35.5% were totally occluded, and 68.7% were calcified. Freedom from clinically-driven target lesion revascularization (CD-TLR) was evaluated through 36 months. The safety composite endpoint was freedom from device- and procedure-related death through 30 days and freedom from major target limb amputation and clinically-driven target vessel revascularization within 36 months. All safety and revascularization events were reviewed by an independent clinical events committee. Results: The Kaplan-Meier estimate of freedom from CD-TLR through 36 months was 76.9%. The composite safety endpoint was achieved in 75.6% of patients. The 36-month all-cause mortality rate was 11.6%, and the major target limb amputation rate was 1.0%. The Kaplan-Meier estimate of freedom from CD-TLR through 36 months was significantly lower in patients with chronic limb-threatening ischemia (CLTI) compared with claudicants (67.6% vs 78.0%; p=0.003). Lesions affecting both the superficial femoral artery (SFA) and popliteal artery had lower Kaplan-Meier freedom from CD-TLR through 36 months (69.2%) than either isolated SFA (79.7%) or popliteal artery lesions (76.5%; log- rank p<0.001). Predictors of CD-TLR through 36 months included increa

Published
2020

17. Drug-Coated Balloon Treatment of Femoropopliteal Lesions for Patients With Intermittent Claudication and Ischemic Rest Pain: 2-Year Results From the IN.PACT Global Study

Author

Micari, A., Brodmann, M., Keirse, K., Peeters, P., Tepe, G., Frost, M., Wang, H., Zeller, T., Torsello, G., Scheinert, D., Bosiers, M., Maene, L., D. -D., Do, Hendriks, J., Merkely, B., Lardenoije, J. -W., Ruzsa, Z., Vogel, B., Veroux, P., Albuquerque e Castro, J., Periard, D., Ludyga, T., Midy, D., Choi, D., Lansink, W., Ketelsen, D., Dubenec, S., Banyai, M., Chakfe, N., Roithinger, F. X., Trani, Carlo, Mansour, H., Rha, S. -W., Vermassen, F., Belenky, A., Spak, L., Chalmers, N., Benko, A., Seerangan, Kumar, Won, J. H., Vozar, M., Tan, K. T., Labib, M., de Borst, G. -J., Y. -S., Do, Teijink, J., Gomez, J. F., Falkowski, A., Ferreira, L., Matela, J., Lee, S. -W., Verhoeven, B., Mannheim, D., Nessi, F., Vulev, I., de Vries, J. -P., Maly, R., Kavteladze, Z., Turner, D., Mendiz, O., Kolvenbach, R., Karnabatidis, D., Cuellar, C., Venermo, M., Velicka, L., and Lundberg, G.

Subjects
Male, Biocompatible, angioplasty, drug-coated balloon, femoropopliteal artery, peripheral artery disease, target lesion revascularization, Aged, Angioplasty, Balloon, Cardiovascular Agents, Constriction, Pathologic, Female, Humans, Intermittent Claudication, Ischemia, Middle Aged, Paclitaxel, Peripheral Arterial Disease, Prospective Studies, Recurrence, Time Factors, Treatment Outcome, Vascular Patency, Coated Materials, Biocompatible, Femoral Artery, Popliteal Artery, Vascular Access Devices, Pathologic, Cardiology and Cardiovascular Medicine, Angioplasty, Coated Materials, Constriction, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Balloon
Published
2018

30. MRT des Annulus fibrosus und der kartilaginären Endplatte lumbaler Bandscheiben mittels ultrakurzen Echozeiten: Quantifizierung degenerativer Veränderungen mittels offresonanten Sättigungsratios

Author

Syha, R, primary, Gebhardt, H, additional, Grosse, U, additional, Martirosian, P, additional, Thomas, C, additional, Ketelsen, D, additional, Notohamiprodjo, M, additional, Nikolaou, K, additional, Schick, F, additional, and Springer, F, additional

Published
2015
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34. Manufacture of the combined primary and tertiary mirrors of the Large Synoptic Survey Telescope

Author

Martin, H. M., additional, Allen, R. G., additional, Burge, J. H., additional, Cuerden, B., additional, Gressler, W., additional, Hubler, W., additional, Ketelsen, D., additional, Kim, D. W., additional, Kingsley, J. S., additional, Law, K., additional, Strittmatter, P. A., additional, Tuell, M. T., additional, West, S. C., additional, Zhao, C., additional, and Zhou, P., additional

Published
2014
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