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5. Monitoring of occupational and environmental aeroallergens – EAACI Position Paper: Concerted action of the EAACI IG Occupational Allergy and Aerobiology & Air Pollution

Author

Raulf, M., Buters, J., Chapman, M., Cecchi, L., de Blay, F., Doekes, G., Eduard, W., Heederik, D., Jeebhay, M. F., Kespohl, S., Krop, E., Moscato, G., Pala, G., Quirce, S., Sander, I., Schlünssen, V., Sigsgaard, T., Walusiak-Skorupa, J., Wiszniewska, M., Wouters, I. M., and Annesi-Maesano, I.

Published
2014
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19. Poster

Author

Fiebig, H., Weber, B., Cromwell, O., Jutel, M., Fiedler, G., Hanschmann, H., Hansen, I., Stuck, B. A., Hörmann, K., Klimek, L., Jappe, U., Hoffmann, M., Burow, G., Mühlmeier, G., Maier, H., Mušič, E., Košnik, M., Piller, M., Drachenberg, K. J., Urban, E., Schenn, A., Ruëff, F., Weimer, G., Przybilla, B., Sieber, W., Schoppelrey, V., Pfeifer, M., Steiß, J. O., Lindemann, H., Wolf, H., Schnitker, J., Petermann, F., Bergmann, K. C., Zwacka, G., Steinert, B., Markert, U. R., Bijlsma, P. B., Backhaus, B., Weidenhiller, M., Donhauser, N., Hahn, E. G., Raithel, M., Erkelens, W., Hommes, D., Bruno, M., Akkerdaas, J., van Ree, R., Groot, J. A., Taminiau, J. A. J. M., Meinardi, M. M. H. M., Borowski, C., Schäfer, T., Eberhardt, F., Lepp, U., Becker, W.-M., Zabel, P., Hipler, U.-C., Spoo, J., Bauer, A., Elsner, P., Kuefner, M. A., Schwelberger, H. G., Lange, L., Rietschel, E., Riffelmann, F., Lauter, H., Müller, K.-M., Tränkner, A., Mach, K., Reulbach, U., Geyer, D., Leis, B., Ziegert, M., Ahlert, I., Deichmann, K. A., Heinzmann, A., Allmers, H., Beezhold, D., Hamilton, R. G., Sutherland, E. R., Schwanitz, H. J., Scherer, K., Bircher, A. J., Dymek, S., Lex, C., Balzer, S., Schuster, A., Hülsmeier, L., Barker, M., Müller-Lux, A., Göen, T., Koll, W., Koschel, D., Müller-Wening, D., Kütting, B., Janicke, N., Schippke, D., Langer, C., Schulz, T. G., Turowski, S., Drexler, H., Hallier, E., Bickeböller, H., Heutelbeck, A. R. R., Lässig, W., Nordwig, A., Dellweg, D., Schwarz, H., Goldmann, R., Lorenz, C., Achtzehn, U., Stehle, R., Keiper, B., Jilge, B., Beier, L., Schmidt, E. W., van Kampen, V., Haamann, F., Merget, R., Sander, I., Raulf-Heimsoth, M., Rabstein, S., Brüning, T., Ahrens, T., Muesken, H., Bergmann, K.-Ch., Vetter, M., Heitmann, M., Hunzelmann, N., Schuster, J., Kadar, J., Kespohl, S., Petersen, A., Meyer, H. E., Sickmann, A., Kleber, N., Hinrichs, J., Schocker, F., Becker, W. M., Rozynek, P., Dresselhaus, T., Reuter, B., Henzgen, M., Fahlbusch, B., Rudeschko, O., Schlenvoigt, G., Kroegel, C., Rihs, H.-P., Gaspar, Â., Pires, G., Hohenstein, E., Fiedler, E.-M., v. Pelchrzim, R., Focke, M., Zuberbier, T., Worm, M., Janowska, E., Grycmacher-Łapko, V., Kurek, M., Lippert, U., Niedenführ, S., Fuchs, T., Ludwig, A., Koch, A., Balda, B.-R., Oestmann, E., Philipp, S., Spornraft-Ragaller, P., Hammermann, J., Meurer, M., Ott, H., Wurpts, G., Krieg, R., Al Masaoudi, T., Joussen, S., Kiehl, K., Neis, M., Merk, H. F., Baron, J. M., Schmengler, J., John, S. M., Blaschke, V., Bonnekoh, B., Holzamer, N., Schmidt, U., Ambach, A., Oppermann, H., Thriene, B., Gollnick, H., Kraus, T., Häberle, M., Hoopmann, M., Hehl, O., Werfel, T., Heidrich, S., Kelber, J., Hünecke, P., Kasche, A., Klaus, S., Thiel, M., Buters, J., Weichenmeier, I., Ring, J., Traidl-Hoffmann, C., Behrendt, H., Krämer, U., Lau, S., Kim, S., Mahling, H., Schulz, G., Keil, T., Wahn, U., Mock, B., Kugler, J., Cremer, R., Sandner, B., Kaiser, F., Herbst, R. A., Wahl, R., Suck, R., Kügler, K., Frosch, P. J., Nabe, A., Konturek, P., Simon, K., Kressel, J., Nägel, A., Wilken, V., Strehfeld, T., Neubert, K., Pieper, B., Kuhn, M., Winterkamp, S., Pacurar, A., Senger, D., Beskitas, E., Dorrmann, H., Mueller, M. W., Harwanegg, C., Hiller, R., Kinne, R. W., Schröder, C. M., Mahler, V., Schröder, A., Erdmann, S., Schultis, H. W., Buchwald, F., Hampel, W., Maiss, J., Naegel, A., Zahradnik, E., Doekes, G., Runge, D. M., Schwertner, H., Grize, L., Schindler, C., Surber, Ch., Böckelmann, R., Horn, T., Breithaupt, S., Thiele, J. J., Gutermuth, J., Jakob, T., Heinzelmann, J., Varosi, F., Debevc, F., Pöhlmann, T. G., Seyfarth, L., Kindt, F., Löser, C., Niemeier, V., Gieler, U., Kummer, W., Haberberger, R. V., Klockenbring, T., Stöcker, M., Huhn, M., Bauer, R., Goerlich, R., Fischer, R., Barth, S., Suchodolska, A., Soost, S., Bayerl, C., Ludwig, B., Gancs, P., Häusermann, P., Harr, T., Müller, M., Sachs, B., Riegel, S., Schichler, D., Schrooten, J., Heussen, N., Hilgers, R.-D., Seo, J. W., Franke, I., and Strauss, R.

Subjects
SIT und Insektengiftallergie, Immunology and Allergy
Published
2004
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20. Monitoring of occupational and environmental aeroallergens-EAACI position paper

Author

Raulf, M., Buters, J., Chapman, M., Cecchi, L., de Blay, F., Doekes, G., Eduard, W., Heederik, D., Jeebhay, M., Kespohl, S., Krop, E.J., Moscato, G., Pala, G., Quirce, S., Sander, I., Schlünssen, V., Sigsgaard, T., Walusiak-Skorupa, J., Wiszniewska, M., Wouters, I.M., and Annesi-Maesano, I.

Subjects
Allergen Monitoring, Environment, Immunological Tests, Occupational Exposure, Sampling Methods, immune system diseases, otorhinolaryngologic diseases, respiratory system, respiratory tract diseases
Abstract

Exposure to high molecular weight sensitizers of biologic origin is an important risk factor for the development of asthma and rhinitis. Most of causal allergens have been defined based on their reactivity with IgE antibodies and in many cases the molecular structure and function of the allergens have been established. Significant information on allergen levels that cause sensitization and allergic symptoms for several major environmental and occupational allergens has been reported. Monitoring of high molecular weight allergens and allergen carrier particles is an important part of the management of allergic respiratory diseases and requires standardized allergen assessment methods for occupational and environmental (indoor and outdoor) allergen exposure. The aim of this EAACI task force was to review the essential points for monitoring environmental and occupational allergen exposure including sampling strategies and methods, processing of dust samples, allergen analysis and quantification. The paper includes a summary of different methods for sampling and allergen quantification, as well as their pros and cons for various exposure settings. Recommendations are being made for different exposure scenarios.

Published
2014

22. How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results

Author

Kespohl, S., primary, Maryska, S., additional, Bünger, J., additional, Hagemeyer, O., additional, Jakob, T., additional, Joest, M., additional, Knecht, R., additional, Koschel, D., additional, Kotschy-Lang, N., additional, Merget, R., additional, Mülleneisen, N. K., additional, Rabe, U., additional, Röseler, S., additional, Sander, I., additional, Stollewerk, D., additional, Straube, H., additional, Ulmer, H. M., additional, van Kampen, V., additional, Walusiak-Skorupa, J., additional, Wiszniewska, M., additional, Wurpts, G., additional, Brüning, T., additional, and Raulf, M., additional

Published
2016
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24. Allergenexposition – wie kann man Inhalationsallergene an Arbeitsplätzen und in der Umwelt messen? Zusammenfassung des „EAACI Positionspapier“ zum Allergenmonitoring

Author

Raulf, M., primary, Buters, J.T.M., additional, Chapman, M., additional, Cecchi, L., additional, Blay, F. de, additional, Doekes, G., additional, Eduard, W., additional, Heederik, D., additional, Jeebhay, M.F., additional, Kespohl, S., additional, Krop, E., additional, Moscato, G., additional, Pala, G., additional, Quirce, S., additional, Sander, I., additional, Schlünssen, V., additional, Sigsgaard, T., additional, Walusiak-Skorupa, J., additional, Wiszniewska, M., additional, Wouters, I.M., additional, and Annesi-Maesano, I., additional

Published
2016
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25. Impact of cross-reactive carbohydrate determinants on wood dust sensitization

Author

Kespohl, S, Schlünssen, V, Jacobsen, Gitte, Schaumburg, Inger, Maryska, S, Meurer, U, Brüning, T, Sigsgaard, Torben, and Raulf-Heimsoth, M

Subjects
Denmark, fungi, Carbohydrates, food and beverages, Proteins, Dust, Allergens, Cross Reactions, Immunoglobulin E, Pinus, complex mixtures, Wood, Occupational Diseases, Occupational Exposure, Fagus, Humans, Rhinitis
Abstract

Occupational wood dust exposure can induce allergy and may be one cause of respiratory health problems among woodworkers.

Published
2010
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26. Schimmelpilzallergie: Sensibilisierungshäufigkeit und Konkordanz verschiedener Hautprickteste im Vergleich zur spezifischen IgE-Bestimmung

Author

Kespohl, S, primary, Maryska, S, additional, Bünger, J, additional, Hagemeyer, O, additional, Jakob, T, additional, Joest, M, additional, Knecht, R, additional, Koschel, D, additional, Kotschy-Lang, N, additional, Merget, R, additional, Mülleneisen, NK, additional, Rabe, U, additional, Röseler, S, additional, Stollewert, D, additional, Straube, H, additional, Ulmer, HM, additional, Walusiak-Skorupa, J, additional, Wiszniewska, M, additional, Wurpts, G, additional, Brüning, T, additional, and Raulf, M, additional

Published
2015
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27. Monitoring of occupational and environmental aeroallergens-- EAACI Position Paper. Concerted action of the EAACI IG Occupational Allergy and Aerobiology & Air Pollution

Author

Raulf, M, Buters, J, Chapman, M, Cecchi, L, de Blay, F, Doekes, G, Eduard, W, Heederik, D, Jeebhay, M F, Kespohl, S, Krop, E, Moscato, G, Pala, G, Quirce, S, Sander, I, Schlünssen, V, Sigsgaard, T, Walusiak-Skorupa, J, Wiszniewska, M, Wouters, I M, Annesi-Maesano, I, Raulf, M, Buters, J, Chapman, M, Cecchi, L, de Blay, F, Doekes, G, Eduard, W, Heederik, D, Jeebhay, M F, Kespohl, S, Krop, E, Moscato, G, Pala, G, Quirce, S, Sander, I, Schlünssen, V, Sigsgaard, T, Walusiak-Skorupa, J, Wiszniewska, M, Wouters, I M, and Annesi-Maesano, I

Abstract

Exposure to high molecular weight sensitizers of biological origin is an important risk factor for the development of asthma and rhinitis. Most of the causal allergens have been defined based on their reactivity with IgE antibodies, and in many cases, the molecular structure and function of the allergens have been established. Significant information on allergen levels that cause sensitization and allergic symptoms for several major environmental and occupational allergens has been reported. Monitoring of high molecular weight allergens and allergen carrier particles is an important part of the management of allergic respiratory diseases and requires standardized allergen assessment methods for occupational and environmental (indoor and outdoor) allergen exposure. The aim of this EAACI task force was to review the essential points for monitoring environmental and occupational allergen exposure including sampling strategies and methods, processing of dust samples, allergen analysis, and quantification. The paper includes a summary of different methods for sampling and allergen quantification, as well as their pros and cons for various exposure settings. Recommendations are being made for different exposure scenarios.

Published
2014

28. Monitoring of occupational and environmental aeroallergens-- EAACI Position Paper. Concerted action of the EAACI IG Occupational Allergy and Aerobiology & Air Pollution

Author

LS IRAS EEPI GRA (Gezh.risico-analyse), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA-SIB, IRAS RATIA2, Raulf, M, Buters, J, Chapman, M, Cecchi, L, de Blay, F, Doekes, G, Eduard, W, Heederik, D, Jeebhay, M F, Kespohl, S, Krop, E, Moscato, G, Pala, G, Quirce, S, Sander, I, Schlünssen, V, Sigsgaard, T, Walusiak-Skorupa, J, Wiszniewska, M, Wouters, I M, Annesi-Maesano, I, LS IRAS EEPI GRA (Gezh.risico-analyse), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA-SIB, IRAS RATIA2, Raulf, M, Buters, J, Chapman, M, Cecchi, L, de Blay, F, Doekes, G, Eduard, W, Heederik, D, Jeebhay, M F, Kespohl, S, Krop, E, Moscato, G, Pala, G, Quirce, S, Sander, I, Schlünssen, V, Sigsgaard, T, Walusiak-Skorupa, J, Wiszniewska, M, Wouters, I M, and Annesi-Maesano, I

Published
2014

30. Occupational IgE-mediated softwood allergy: characterization of the causative allergen

Author

Kespohl, S., Kotschy-Lang, N., Tomm, Janina, von Bergen, Martin, Maryska, S., Brüning, T., Raulf-Heimsoth, M., Kespohl, S., Kotschy-Lang, N., Tomm, Janina, von Bergen, Martin, Maryska, S., Brüning, T., and Raulf-Heimsoth, M.

Abstract

Allergic reactions to wood dust allergens are rare, and only few in vitro diagnostic tools and information about relevant allergens are available. To differentiate between protein-based allergy and probably clinically silent glycogenic sensitization, it is helpful to characterize the relevant protein allergens and specify IgE binding. The current case report deals with the occupational softwood allergy of a carpenter exposed to different wood dusts. Skin tests and IgE tests against wood were performed with specifically tailored ImmunoCAPs and cross-reactive carbohydrate determinants. Potential allergens were identified by IgE blots and tandem mass spectrometry. The clinical relevance was verified by challenge tests. Specific IgE to softwood (spruce, pine and larch wood), beech wood, natural rubber latex (NRL) and horseradish peroxidase (HRP) were detected. Allergens in spruce wood, the dominant allergen source, were identified as peroxidases. Softwood were the strongest inhibitors. HRP reduced IgE binding to softwood to <50%, indicating predominantly proteinogenic epitopes, whereas IgE binding to NRL and beech wood was reduced to >50% by HRP, indicating predominantly glycogenic IgE epitopes. Skin and challenge tests underlined that softwoods were the source of sensitization. For the polysensitized patient, a clinically relevant softwood allergy was diagnosed, not only by challenge tests but also with specifically tailored in vitro tools.

Published
2012

34. Poster Session 2

Author

Andersson, T., primary, Magnusson, A., additional, Bryngelsson, I.- L., additional, Frobert, O., additional, Henriksson, K. M., additional, Edvardsson, N., additional, Poci, D., additional, Polovina, M., additional, Potpara, T., additional, Licina, M., additional, Mujovic, N., additional, Kocijancic, A., additional, Simic, D., additional, Ostojic, M. C., additional, Providencia, R. A., additional, Botelho, A., additional, Trigo, J., additional, Nascimento, J., additional, Quintal, N., additional, Mota, P., additional, Leitao-Marques, A. M., additional, Bosch, R. F., additional, Kirch, W., additional, Rosin, L., additional, Willich, S. N., additional, Pittrow, D., additional, Bonnemeier, H., additional, Valenza, M. C., additional, Martin, L., additional, Munoz Casaubon, T., additional, Valenza, G., additional, Botella, M., additional, Serrano, M., additional, Valenza, B., additional, Cabrera, I., additional, Anderson, K., additional, Benzaquen, B. S., additional, Koziolova, N., additional, Nikonova, J., additional, Shilova, Y., additional, Scherr, D., additional, Narayan, S., additional, Wright, M., additional, Krummen, D., additional, Jadidi, A., additional, Jais, P., additional, Haissaguerre, M., additional, Hocini, M., additional, Hunter, R., additional, Liu, Y., additional, Lu, Y., additional, Wang, W., additional, Schilling, R. J., additional, Bernstein, S., additional, Wong, B., additional, Rooke, R., additional, Vasquez, C., additional, Shah, R., additional, Rosenberg, S., additional, Chinitz, L., additional, Morley, G., additional, Bashir Choudhary, M., additional, Holmqvist, F., additional, Carlson, J., additional, Nilsson, H.- J., additional, Platonov, P. G., additional, Jadidi, A. S., additional, Cochet, H., additional, Miyazaki, S., additional, Shah, A. J., additional, Marrouche, N., additional, Calvo, N., additional, Nadal, M., additional, Andreu, D., additional, Tamborero, D., additional, Diaz, F. E., additional, Berruezo, A., additional, Brugada, J., additional, Mont, L., additional, Fichtner, S., additional, Hessling, G., additional, Estner, H. L., additional, Jilek, C., additional, Reents, T., additional, Ammar, S., additional, Wu, J., additional, Deisenhofer, I., additional, Nakanishi, H., additional, Kashiwase, K., additional, Hirata, A., additional, Wada, M., additional, Ueda, Y., additional, Skoda, J., additional, Neuzil, P., additional, Popelova, J., additional, Petru, J., additional, Sediva, L., additional, Reddy, V. Y., additional, Uldry, L., additional, Forclaz, A., additional, Virag, N., additional, Vesin, J.- M., additional, Kappenberger, L., additional, Sehra, R., additional, Briggs, C., additional, Rappel, W.- J., additional, Janotka, M., additional, Chovanec, M., additional, Yamashiro, K., additional, Takami, K., additional, Sakamoto, Y., additional, Satoh, K., additional, Suzuki, T., additional, Nakagawa, H., additional, Romanov, A., additional, Pokushalov, E., additional, Artemenko, S., additional, Shabanov, V., additional, Stenin, I., additional, Elesin, D., additional, Turov, A., additional, Yakubov, A., additional, Hioki, M., additional, Matsuo, S., additional, Ito, K., additional, Narui, R., additional, Yamashita, S., additional, Sugimoto, K., additional, Yoshimura, M., additional, Yamane, T., additional, Di Biase, L., additional, Gallinghouse, J. D., additional, Rajappan, K., additional, Kautzner, J., additional, Dello Russo, A., additional, Tondo, C., additional, Lorgat, F., additional, Natale, A., additional, Balta, O., additional, Buenz, K., additional, Paessler, M., additional, Anders, H., additional, Horlitz, M., additional, Deneke, T., additional, Lickfett, L., additional, Liberman, I., additional, Linhart, M., additional, Andrie, R., additional, Mittmann-Braun, E., additional, Stockigt, F., additional, Nickenig, G., additional, Schrickel, J., additional, Tilz, R., additional, Rillig, A., additional, Feige, B., additional, Metzner, A., additional, Fuernkranz, A., additional, Burchard, A., additional, Wissner, E., additional, Ouyang, F., additional, Betts, T. R., additional, Jones, M. A., additional, Wong, K. C. K., additional, Qureshi, N., additional, Bashir, Y., additional, Corbucci, G., additional, Losik, D., additional, Selina, V., additional, Crandall, M. A., additional, Daniels, C., additional, Daoud, E., additional, Kalbfleisch, S., additional, Yamaji, H., additional, Murakami, T., additional, Kawamura, H., additional, Murakami, M., additional, Hina, K., additional, Kusachi, S., additional, Dakos, G., additional, Vassilikos, V., additional, Paraskevaidis, S., additional, Mantziari, A., additional, Theophylogiannakos, S., additional, Chouvarda, I., additional, Chatzizisis, I., additional, Styliadis, I., additional, Kimura, T., additional, Fukumoto, K., additional, Nishiyama, N., additional, Aizawa, Y., additional, Fukuda, Y., additional, Sato, T., additional, Miyoshi, S., additional, Takatsuki, S., additional, Navarrete Casas, A. J., additional, Ali, I., additional, Conte, F. C., additional, Moran, M., additional, Graham, B. G., additional, Kalejs, O., additional, Lacis, R., additional, Stradins, P., additional, Koris, A., additional, Putnins, I., additional, Vikmane, M., additional, Lejnieks, A., additional, Erglis, A., additional, Estrada, A., additional, Perez Silva, A., additional, Castrejon, S., additional, Doiny, D., additional, Merino, J. L., additional, Baranchuk, A., additional, Greiss, I., additional, Simpson, C. S., additional, Abdollah, H., additional, Redfearn, D. P., additional, Buys-Topart, M., additional, Nitzsche, R., additional, Thibault, B., additional, Kathan, S., additional, Kolb, C., additional, Reif, S., additional, Schade, S., additional, Taggeselle, J., additional, Frey, A., additional, Birkenhagen, A., additional, Kohler, S., additional, Schmidt, M., additional, Cano Perez, O., additional, Buendia, F., additional, Igual, B., additional, Osca, J. M., additional, Sanchez, J. M., additional, Sancho-Tello, M. J., additional, Olague, J. M., additional, Salvador, A., additional, Tolosana, J. M., additional, Fernandez-Armenta, J., additional, Matas, M., additional, Barbarin, M. C., additional, Habibovic, M., additional, Van Den Broek, K. C., additional, Theuns, D. A. M. J., additional, Jordaens, L., additional, Alings, M., additional, Van Der Voort, P. H., additional, Pedersen, S. S., additional, Pupita, G., additional, Molini, S., additional, Brambatti, M., additional, Capucci, A., additional, Molodykh, S., additional, Idov, E. M., additional, Belyaev, O. V., additional, Segreti, L., additional, Soldati, E., additional, Zucchelli, G., additional, Di Cori, A., additional, Viani, S., additional, Paperini, L., additional, De Lucia, R., additional, Bongiorni, M. G., additional, Binner, L., additional, Taborsky, M., additional, Bello, D., additional, Heuer, H., additional, Ramza, B., additional, Jenniskens, I., additional, Johnson, W. B., additional, Silvetti, M. S., additional, Rava', L., additional, Russo, M. S., additional, Di Mambro, C., additional, Ammirati, A., additional, Gimigliano, G., additional, Prosperi, M., additional, Drago, F., additional, Santos, A. R., additional, Picarra, B., additional, Semedo, P., additional, Dionisio, P., additional, Matos, R., additional, Leitao, M., additional, Jacinto, A., additional, Trinca, M., additional, Mazzone, P., additional, Ciconte, G., additional, Marzi, A., additional, Paglino, G., additional, Vergara, P., additional, Sora, N., additional, Gulletta, S., additional, Della Bella, P., additional, Koppitz, P., additional, Fach, A., additional, Hobbiesiefken, S., additional, Fiehn, E., additional, Hambrecht, R., additional, Sperzel, J., additional, Jung, M., additional, Schmitt, J., additional, Pajitnev, D., additional, Burger, H., additional, Goebel, G., additional, Ehrlich, W., additional, Walther, T., additional, Ziegelhoeffer, T., additional, Vancura, V., additional, Wichterle, D., additional, Melenovsky, V., additional, Glikson, M., additional, Goldenberg, G., additional, Segev, A., additional, Dvir, D., additional, Kuzniec, J., additional, Finkelstein, A., additional, Hay, I., additional, Guetta, V., additional, Choo, W. K., additional, Gupta, S., additional, Kirkfeldt, R., additional, Johansen, J., additional, Nohr, E., additional, Moller, M., additional, Arnsbo, P., additional, Nielsen, J., additional, Banha, M., additional, Stojanov, P., additional, Raspopovic, S., additional, Vasic, D., additional, Savic, D., additional, Nikcevic, G., additional, Jovanovic, V., additional, Defaye, P., additional, Mondesert, B., additional, Mbaye, A., additional, Cassagneau, R., additional, Gagniere, V., additional, Jacon, J., additional, Sanfins, V., additional, Reis, H. R., additional, Nobre, J. N., additional, Martins, V. M., additional, Duarte, L. D., additional, Morais, C. M., additional, Conceicao, J. C., additional, Hero, M., additional, Rey, J. L., additional, Ducharme, A., additional, Simpson, C., additional, Stuglin, C., additional, Blier, L., additional, Senaratne, M., additional, Khaykin, Y., additional, Pinter, A., additional, Mlynarska, A., additional, Mlynarski, R., additional, Sosnowski, M., additional, Wilczek, J., additional, Iorgulescu, C., additional, Bogdan, S., additional, Constantinescu, D., additional, Caldararu, C., additional, Dorobantu, M., additional, Radu, A., additional, Vatasescu, R.- G., additional, Yusu, S., additional, Ikeda, T., additional, Mera, H., additional, Miwa, Y., additional, Abe, A., additional, Miyakoshi, M., additional, Tsukada, T., additional, Yoshino, H., additional, Nayar, V., additional, Cantelon, P., additional, Rawling, A., additional, Belham, M. R. D., additional, Pugh, P. J., additional, Osca Asensi, J., additional, Cano, O., additional, Tejada, D., additional, Munoz, B., additional, Rodriguez, M., additional, Olague, J., additional, Wecke, L., additional, Van Hunnik, A., additional, Thompson, T., additional, Di Carlo, L., additional, Zdeblick, M., additional, Auricchio, A., additional, Prinzen, F., additional, Doltra Magarolas, A., additional, Bijnens, B., additional, Silva, E., additional, Penela, D., additional, Sitges, M., additional, Ofman, P., additional, Navaravong, L., additional, Leng, J., additional, Peralta, A., additional, Hoffmeister, P., additional, Levine, R., additional, Cook, J., additional, Stoenescu, M., additional, Tettamanti, M. E., additional, Revilla Orodea, A., additional, Lopez Diaz, J., additional, De La Fuente Galan, L., additional, Arnold, R., additional, Garcia Moran, E., additional, San Roman Calvar, J. 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Published
2011
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35. Diagnostik I

Author

Becker, W., primary, Jappe, U., additional, Kreft, B., additional, Ludwig, A., additional, Przybilla, B., additional, Walker, A., additional, Biedermann, T., additional, Raulf-Heimsoth, M., additional, Sültz, J., additional, Petersen, A., additional, Seppälä, U., additional, Dauly, C., additional, Robinson, S., additional, Hornshaw, M., additional, Nedergaard, J., additional, Ipsen, H., additional, Seyfarth, F., additional, Hipler, U.-C., additional, Schliemann, S., additional, Elsner, P., additional, Ausner, E., additional, Seelinger, M., additional, Matthias, J., additional, Kirsch, A. I., additional, Oberhofer, E., additional, Möhrenschlager, M., additional, Ring, J., additional, Menz, G., additional, Kespohl, S., additional, Förster, T., additional, Maryska, S., additional, Brüning, T., additional, Neumeister, V., additional, Nemat, K., additional, Hauswald, B., additional, Spornraft-Ragaller, P., additional, Blank, S., additional, Seismann, H., additional, Michel, Y., additional, McIntyre, M., additional, Cifuentes, L., additional, Braren, I., additional, Grunwald, T., additional, Darsow, U., additional, Bredehorst, R., additional, Ollert, M., additional, Spillner, E., additional, Christensen, L. H., additional, Amondsen, P., additional, Henmar, H., additional, Bergmann, K., additional, Schmidt, A., additional, Staatz, A., additional, Strohner, P., additional, Becher, G., additional, Nährlich, L., additional, Rudloff, S., additional, Steiß, J.-O., additional, Lange, L., additional, Sonntag, H., additional, Buderus, S., additional, Wahl, R., additional, Kraus, R., additional, Urbanek, R., additional, Grychtol, R., additional, Meinicke, H., additional, Müller, C., additional, Heinzmann, A., additional, Schiller, D., additional, Kühne, Y., additional, Becker, S., additional, Ballmer-Weber, B., additional, Niggemann, B., additional, Scibilia, J., additional, Bindslev-Jensen, C., additional, Wackermann, O., additional, Reese, G., additional, Vieths, S., additional, Holzhauser, T., additional, Gröger, M., additional, Canis, M., additional, Kramer, M., additional, Beck, I., additional, Jochner, S., additional, Gilles, S., additional, Schmidt-Weber, C., additional, Menzel, A., additional, Behrendt, H., additional, Traidl-Hoffmann, C., additional, Waßmann, A., additional, Wichmann, K., additional, Heratizadeh, A., additional, Wedi, B., additional, Kapp, A., additional, and Werfel, T., additional

Published
2011
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41. Symposium 8: Bestimmung von (inhalativen) Expositionen und Belastungen

Author

Kuhlbusch, T. A. J., primary, Raulf-Heimsoth, M., additional, Sander, I., additional, Zahradnik, E., additional, Kespohl, S., additional, Brüning, T., additional, Doekes, G., additional, Noss, I., additional, Wouters, I. M., additional, Thorne, P. S., additional, Brunekreef, B., additional, and Heederik, D. J. J., additional

Published
2007
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42. Allergene — Allergenträger — Pseudoallergien — Adjuvanzien

Author

Grosber, M., primary, Eberlein, B., additional, Engst, R., additional, Kerzl, R., additional, Manstein, P., additional, Ring, J., additional, Darsow, U., additional, Termeer, C., additional, Termeer, J., additional, Salmann, S., additional, Averbeck, M., additional, Simon, J., additional, Pfaar, O., additional, von Weikersthal-Drachenberg, K. Fischer, additional, Amersdorffer, J., additional, Baumann-Noss, S., additional, Woroniecki, S., additional, Klimek, L., additional, Lauter, H., additional, Sager, A., additional, Laszczyk, M., additional, Scheffler, A., additional, Martin, S., additional, Kespohl, S., additional, Schlünssen, V., additional, Jacobsen, G., additional, Sigsgaard, T., additional, Maryska, S., additional, Meurer, U., additional, Brüning, T., additional, Raulf-Heimsoth, M., additional, Riecken, S., additional, Lindner, B., additional, Petersen, A., additional, Jappe, U., additional, Becker, W., additional, Saloga, J., additional, Häringer, B., additional, Bellinghausen, I., additional, Lafargue, B., additional, Decker, H., additional, Grabbe, S., additional, Baratli, J., additional, Asturias, J., additional, Hunzelmann, N., additional, Kahlert, H., additional, Weber, B., additional, Cromwell, O., additional, Fiebig, H., additional, Nandy, A., additional, and Wald, M., additional

Published
2007
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48. Inhalationsallergien am Arbeitsplatz.

Author

Raulf-Heimsoth, M., Kampen, V., Kespohl, S., Sander, I., Merget, R., and Brüning, T.

Abstract

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Published
2012
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49. Original article Cross-reactivity between obeche wood ( Triplochiton scleroxylon) and natural rubber latex.

Author

Venturini, M., Gastaminza, G., Kespohl, S., Bernedo, N., Garmendia, M., Raulf-Heimsoth, M., Muñoz, D., and Ansotegui, I. J.

Subjects
OCCUPATIONAL diseases, ALLERGENS, PLANT proteins, ALLERGIES, SYMPTOMS, PROTEINS
Abstract

Several studies have shown that allergy to natural rubber latex is associated with cross reactivity to other plants. We have investigated a possible cross reactivity with a tree belonging to the Sterculiaceae family, Tryplochiton scleroxylon, in a patient allergic to obeche wood, that began to suffer symptoms of allergy in contact with latex. Determinations of specific IgE by CAP to obeche, natural rubber latex (NRL) and recombinant allergens of latex were done. Immunoblotting was performed to study allergens detected by serum of our patient. CAP-inhibition methods were used to study cross-reactive between NRL and obeche wood. In obeche extract, 4 bands were found of an apparent molecular weight of 18, 38, 75 and 199 kDa. In NRL extract the allergens have a molecular weight around 18, 21, 32, 38, 60, 70 and 199 kDa. IgE to latex was almost completely inhibited (96%) by the obeche extract in CAP-inhibition studies. Using obeche extract as inhibitor, IgE binding to native hevein (nHevb 6.02) was reduced by 25%. The results obtained in CAP-inhibition demonstrate the existence of cross-reactivity between proteins in NRL and obeche wood. In our patient, a band of apparent molecular weight of 38 kDa could be the most important allergen. [ABSTRACT FROM AUTHOR]

Published
2004
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