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14 results on '"Kerstjens, M."'

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1. A Solve-RD ClinVar-based reanalysis of 1522 index cases from ERN-ITHACA reveals common pitfalls and misinterpretations in exome sequencing

2. Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia

3. Antileukemic efficacy of BET inhibitor in a preclinical mouse model of MLL-AF4 + infant ALL

4. The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitination axis

5. The HDAC inhibitor panobinostat (LBH589) exerts in vivo anti-leukaemic activity against MLL-rearranged acute lymphoblastic leukaemia and involves the RNF20/RNF40/WAC-H2B ubiquitination axis

6. Antileukemic Efficacy of BET Inhibitor in a Preclinical Mouse Model of MLL-AF4+ Infant ALL

7. High-Throughput Drug Library Screening in Primary KMT2A -Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling.

8. Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric MLL -Rearranged Acute Lymphoblastic Leukemia.

9. High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells.

10. Preclinical efficacy of gemcitabine in MLL-rearranged infant acute lymphoblastic leukemia.

11. Decitabine mildly attenuates MLL -rearranged acute lymphoblastic leukemia in vivo, and represents a poor chemo-sensitizer.

12. Trametinib inhibits RAS -mutant MLL -rearranged acute lymphoblastic leukemia at specific niche sites and reduces ERK phosphorylation in vivo .

13. MEK inhibition is a promising therapeutic strategy for MLL-rearranged infant acute lymphoblastic leukemia patients carrying RAS mutations.

14. Nephrogenic diabetes insipidus in a patient with L1 syndrome: a new report of a contiguous gene deletion syndrome including L1CAM and AVPR2.

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