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2. CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Author

Houthuijzen, Julia M., de Bruijn, Roebi, van der Burg, Eline, Drenth, Anne Paulien, Wientjens, Ellen, Filipovic, Tamara, Bullock, Esme, Brambillasca, Chiara S., Pulver, Emilia M., Nieuwland, Marja, de Rink, Iris, van Diepen, Frank, Klarenbeek, Sjoerd, Kerkhoven, Ron, Brunton, Valerie G., Scheele, Colinda L.G.J., Boelens, Mirjam C., and Jonkers, Jos

Published
2023
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6. Corrigendum to “Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer” [Eur Urol 2023;83:313–17]

Author

Gil-Jimenez, Alberto, primary, van Dorp, Jeroen, additional, Contreras-Sanz, Alberto, additional, van der Vos, Kristan, additional, Vis, Daniel J., additional, Braaf, Linde, additional, Broeks, Annegien, additional, Kerkhoven, Ron, additional, van Kessel, Kim E.M., additional, Ribal, María José, additional, Alcaraz, Antonio, additional, Wessels, Lodewyk F.A., additional, Seiler, Roland, additional, Wright, Jonathan L., additional, Mengual, Lourdes, additional, Boormans, Joost, additional, van Rhijn, Bas W.G., additional, Black, Peter C., additional, and van der Heijden, Michiel S., additional

Published
2023
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7. Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer

Author

Gil-Jimenez, Alberto, primary, van Dorp, Jeroen, additional, Contreras-Sanz, Alberto, additional, van der Vos, Kristan, additional, Vis, Daniel J., additional, Braaf, Linde, additional, Broeks, Annegien, additional, Kerkhoven, Ron, additional, van Kessel, Kim E.M., additional, Ribal, María José, additional, Alcaraz, Antonio, additional, Wessels, Lodewyk F.A., additional, Seiler, Roland, additional, Wright, Jonathan L., additional, Mengual, Lourdes, additional, Boormans, Joost, additional, van Rhijn, Bas W.G., additional, Black, Peter C., additional, and van der Heijden, Michiel S., additional

Published
2023
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8. Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer

Author

Gil Jimenez, A. (author), van Dorp, Jeroen (author), Contreras-Sanz, Alberto (author), van der Vos, Kristan (author), Vis, Daniel J. (author), Braaf, Linde (author), Broeks, Annegien (author), Kerkhoven, Ron (author), van Kessel, Kim E.M. (author), Wessels, L.F.A. (author), Gil Jimenez, A. (author), van Dorp, Jeroen (author), Contreras-Sanz, Alberto (author), van der Vos, Kristan (author), Vis, Daniel J. (author), Braaf, Linde (author), Broeks, Annegien (author), Kerkhoven, Ron (author), van Kessel, Kim E.M. (author), and Wessels, L.F.A. (author)

Abstract

Cisplatin-based neoadjuvant chemotherapy (NAC) followed by radical cystectomy is recommended for patients with muscle-invasive bladder cancer (MIBC). It has been shown that somatic deleterious mutations in ERCC2, gain-of-function mutations in ERBB2, and alterations in ATM, RB1, and FANCC are correlated with pathological response to NAC in MIBC. The objective of this study was to validate these genomic biomarkers in pretreatment transurethral resection material from an independent retrospective cohort of 165 patients with MIBC who subsequently underwent NAC and radical surgery. Patients with ypT0/Tis/Ta/T1N0 disease after surgery were defined as responders. Somatic deleterious mutations in ERCC2 were found in nine of 68 (13%) evaluable responders and two of 95 (2%) evaluable nonresponders (p = 0.009; FDR = 0.03). No correlation was observed between response and alterations in ERBB2 or in ATM, RB1, or FANCC alone or in combination. In an exploratory analysis, no additional genomic alterations discriminated between responders and nonresponders to NAC. No further associations were identified between the aforementioned biomarkers and pathological complete response (ypT0N0) after surgery. In conclusion, we observed a positive association between deleterious mutations in ERCC2 and pathological response to NAC, but not overall survival or recurrence-free survival. Other previously reported genomic biomarkers were not validated. Patient summary: It is currently unknown which patients will respond to chemotherapy before definitive surgery for bladder cancer. Previous studies described several gene mutations in bladder cancer that correlated with chemotherapy response. This study confirmed that patients with bladder cancer with a mutation in the ERCC2 gene often respond to chemotherapy., Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public. Corrigendum to “Assessment of Predictive Genomic Biomarkers for Response to Cisplatin-based Neoadjuvant Chemotherapy in Bladder Cancer” [Eur Urol 2023;83:313–17] (European Urology (2023) 83(4) (313–317), (S0302283822025386), (10.1016/j.eururo.2022.07.023)) The authors regret that the following statement regarding author contributions was missed: Kristan van der Vos is currently a Scientific Editor for Cell Reports Medicine, which is published by Elsevier. Dr van der Vos was not involved in the peer-review process or editorial discussions about this manuscript. The authors would like to apologise for any inconvenience caused., Pattern Recognition and Bioinformatics

Published
2023
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10. CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary

Author

Xue, Yibo, Meehan, Brian, Macdonald, Elizabeth, Venneti, Sriram, Wang, Xue Qing D., Witkowski, Leora, Jelinic, Petar, Kong, Tim, Martinez, Daniel, Morin, Geneviève, Firlit, Michelle, Abedini, Atefeh, Johnson, Radia M., Cencic, Regina, Patibandla, Jay, Chen, Hongbo, Papadakis, Andreas I., Auguste, Aurelie, de Rink, Iris, Kerkhoven, Ron M., Bertos, Nicholas, Gotlieb, Walter H., Clarke, Blaise A., Leary, Alexandra, Witcher, Michael, Guiot, Marie-Christine, Pelletier, Jerry, Dostie, Josée, Park, Morag, Judkins, Alexander R., Hass, Ralf, Levine, Douglas A., Rak, Janusz, Vanderhyden, Barbara, Foulkes, William D., and Huang, Sidong

Published
2019
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11. Supplementary Information from Pretreatment microRNA Expression Impacting on Epithelial-to-Mesenchymal Transition Predicts Intrinsic Radiosensitivity in Head and Neck Cancer Cell Lines and Patients

Author

de Jong, Monique C., primary, ten Hoeve, Jelle J., primary, Grénman, Reidar, primary, Wessels, Lodewyk F., primary, Kerkhoven, Ron, primary, te Riele, Hein, primary, van den Brekel, Michiel W.M., primary, Verheij, Marcel, primary, and Begg, Adrian C., primary

Published
2023
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12. Data from Search for a Gene Expression Signature of Breast Cancer Local Recurrence in Young Women

Author

Servant, Nicolas, primary, Bollet, Marc A., primary, Halfwerk, Hans, primary, Bleakley, Kevin, primary, Kreike, Bas, primary, Jacob, Laurent, primary, Sie, Daoud, primary, Kerkhoven, Ron M., primary, Hupé, Philippe, primary, Hadhri, Rim, primary, Fourquet, Alain, primary, Bartelink, Harry, primary, Barillot, Emmanuel, primary, Sigal-Zafrani, Brigitte, primary, and van de Vijver, Marc J., primary

Published
2023
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14. Supplementary Figure 1 and Tables 1-8 from Pretreatment microRNA Expression Impacting on Epithelial-to-Mesenchymal Transition Predicts Intrinsic Radiosensitivity in Head and Neck Cancer Cell Lines and Patients

Author

de Jong, Monique C., primary, ten Hoeve, Jelle J., primary, Grénman, Reidar, primary, Wessels, Lodewyk F., primary, Kerkhoven, Ron, primary, te Riele, Hein, primary, van den Brekel, Michiel W.M., primary, Verheij, Marcel, primary, and Begg, Adrian C., primary

Published
2023
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15. Supplementary Tables 1-4, Figure 1 from Search for a Gene Expression Signature of Breast Cancer Local Recurrence in Young Women

Author

Servant, Nicolas, primary, Bollet, Marc A., primary, Halfwerk, Hans, primary, Bleakley, Kevin, primary, Kreike, Bas, primary, Jacob, Laurent, primary, Sie, Daoud, primary, Kerkhoven, Ron M., primary, Hupé, Philippe, primary, Hadhri, Rim, primary, Fourquet, Alain, primary, Bartelink, Harry, primary, Barillot, Emmanuel, primary, Sigal-Zafrani, Brigitte, primary, and van de Vijver, Marc J., primary

Published
2023
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16. Supplementary Figure 4 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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17. Supplementary Table 9 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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18. Supplementary Table 7 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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19. Data from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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20. Supplementary Figure 6 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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21. Supplementary Figure 2 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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22. Supplementary Table 4 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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23. Supplementary Table 2 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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24. Supplementary Table 5 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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25. Supplementary Methods, Figure Legend from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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26. Supplementary Figure 1 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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27. Supplementary Table 3 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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28. Supplementary Table 6 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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29. Supplementary Figure 5 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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30. Supplementary Table 10 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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31. Supplementary Figure 3 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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32. Supplementary Table 8 from Hallmarks of Aromatase Inhibitor Drug Resistance Revealed by Epigenetic Profiling in Breast Cancer

Author

Jansen, Maurice P.H.M., primary, Knijnenburg, Theo, primary, Reijm, Esther A., primary, Simon, Iris, primary, Kerkhoven, Ron, primary, Droog, Marjolein, primary, Velds, Arno, primary, van Laere, Steven, primary, Dirix, Luc, primary, Alexi, Xanthippi, primary, Foekens, John A., primary, Wessels, Lodewyk, primary, Linn, Sabine C., primary, Berns, Els M.J.J., primary, and Zwart, Wilbert, primary

Published
2023
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34. CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Author

Houthuijzen, Julia M., primary, de Bruijn, Roebi, additional, van der Burg, Eline, additional, Drenth, Anne Paulien, additional, Wientjens, Ellen, additional, Filipovic, Tamara, additional, Bullock, Esme, additional, Brambillasca, Chiara S., additional, Nieuwland, Marja, additional, de Rink, Iris, additional, van Diepen, Frank, additional, Klarenbeek, Sjoerd, additional, Kerkhoven, Ron, additional, Brunton, Valerie G., additional, Scheele, Colinda L.G.J., additional, Boelens, Mirjam C., additional, and Jonkers, Jos, additional

Published
2022
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39. BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential

Author

Severson, Tesa M., Peeters, Justine, Majewski, Ian, Michaut, Magali, Bosma, Astrid, Schouten, Philip C., Chin, Suet-Feung, Pereira, Bernard, Goldgraben, Mae A., Bismeijer, Tycho, Kluin, Roelof J.C., Muris, Jettie J.F., Jirström, Karin, Kerkhoven, Ron M., Wessels, Lodewyk, Caldas, Carlos, Bernards, René, Simon, Iris M., and Linn, Sabine

Published
2015
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40. Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms

Author

Schouten, Philip C., Grigoriadis, Anita, Kuilman, Thomas, Mirza, Hasan, Watkins, Johnathan A., Cooke, Saskia A., van Dyk, Ewald, Severson, Tesa M., Rueda, Oscar M., Hoogstraat, Marlous, Verhagen, Caroline V.M., Natrajan, Rachael, Chin, Suet-Feung, Lips, Esther H., Kruizinga, Janneke, Velds, Arno, Nieuwland, Marja, Kerkhoven, Ron M., Krijgsman, Oscar, Vens, Conchita, Peeper, Daniel, Nederlof, Petra M., Caldas, Carlos, Tutt, Andrew N., Wessels, Lodewyk F., and Linn, Sabine C.

Published
2015
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41. High-throughput identification of antigen-specific TCRs by TCR gene capture

Author

Linnemann, Carsten, Heemskerk, Bianca, Kvistborg, Pia, Kluin, Roelof J.C., Bolotin, Dmitriy A., Chen, Xiaojing, Bresser, Kaspar, Nieuwland, Marja, Schotte, Remko, Michels, Samira, Gomez-Eerland, Raquel, Jahn, Lorenz, Hombrink, Pleun, Legrand, Nicolas, Shu, Chengyi Jenny, Mamedov, Ilgar Z., Blank, Christian U., Haanen, John B.A.G., Turchaninova, Maria A., Kerkhoven, Ron M., Spits, Hergen, Hadrup, Sine Reker, Heemskerk, Mirjam H.M., Blankenstein, Thomas, Chudakov, Dmitriy M., Bendle, Gavin M., and Schumacher, Ton N.M.

Subjects
Nucleotide sequencing -- Research, T cells -- Receptors, Antigen receptors, T cell -- Identification and classification, Gene therapy -- Methods, Viral antibodies -- Identification and classification, DNA sequencing -- Research, Cancer -- Care and treatment, Antibodies -- Identification and classification, Biological sciences, Health
Abstract

The transfer of T cell receptor (TCR) genes into patient T cells is a promising approach for the treatment of both viral infections and cancer. Although efficient methods exist to [...]

Published
2013
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43. The Ig heavy chain protein but not its message controls early B cell development

Author

Hubrecht Institute with UMC, Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Hao, Bingtao, Krijger, Peter H L, Pritchard, Colin E J, de Rink, Iris, Muhaimin, Fitriari Izzatunnisa, Nurzijah, Ika, van Baalen, Martijn, Kerkhoven, Ron M, van den Berk, Paul C M, Skok, Jane A, Jacobs, Heinz, Hubrecht Institute with UMC, Aslam, Muhammad Assad, Alemdehy, Mir Farshid, Hao, Bingtao, Krijger, Peter H L, Pritchard, Colin E J, de Rink, Iris, Muhaimin, Fitriari Izzatunnisa, Nurzijah, Ika, van Baalen, Martijn, Kerkhoven, Ron M, van den Berk, Paul C M, Skok, Jane A, and Jacobs, Heinz

Published
2020

44. A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Author

Berns, Katrien, Hijmans, E. Marielle, Mullenders, Jasper, Brummelkamp, Thijn R., Velds, Arno, Heimerikx, Mike, Kerkhoven, Ron M., Madiredjo, Mandy, Nijkamp, Wouter, Weigelt, Britta, Agami, Reuven, Ge, Wei, Cavet, Guy, Linsley, Peter S., Beijersbergen, Roderick L., and Bernards, Rene

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): Katrien Berns [1, 5]; E. Marielle Hijmans [1, 5]; Jasper Mullenders [1]; Thijn R. Brummelkamp [1]; Arno Velds [1]; Mike Heimerikx [1]; Ron M. Kerkhoven [1]; Mandy Madiredjo [1]; [...]

Published
2004
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45. Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing

Author

Majewski, Ian J, Mittempergher, Lorenza, Davidson, Nadia M, Bosma, Astrid, Willems, Stefan M, Horlings, Hugo M, de Rink, Iris, Greger, Liliana, Hooijer, Gerrit KJ, Peters, Dennis, Nederlof, Petra M, Hofland, Ingrid, de Jong, Jeroen, Wesseling, Jelle, Kluin, Roelof JC, Brugman, Wim, Kerkhoven, Ron, Nieboer, Frank, Roepman, Paul, Broeks, Annegien, Muley, Thomas R, Jassem, Jacek, Niklinski, Jacek, van Zandwijk, Nico, Brazma, Alvis, Oshlack, Alicia, van den Heuvel, Michel, and Bernards, René

Published
2013
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46. Gene expression profiling predicts clinical outcome of breast cancer

Author

van 't Veer, Laura J., Dai, Hongyue, van de Vijver, Marc J., He, Yudong D., Hart, Augustinus A. M., Mao, Mao, Peterse, Hans L., van der Kooy, Karin, Marton, Matthew J., Witteveen, Anke T., Schreiber, George J., Kerkhoven, Ron M., Roberts, Chris, Linsley, Peter S., Bernards, Rene, and Friend, Stephen H.

Subjects
Environmental issues, Science and technology, Zoology and wildlife conservation
Abstract

Author(s): Laura J. van 't Veer [1, 2]; Hongyue Dai [2, 3]; Marc J. van de Vijver [1, 2]; Yudong D. He [3]; Augustinus A. M. Hart [1]; Mao Mao [...]

Published
2002
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47. Comprehensive analysis of cutaneous and uveal melanoma liver metastases

Author

Hoefsmit, Esmee P, primary, Rozeman, Elisa A, additional, Van, Trieu My, additional, Dimitriadis, Petros, additional, Krijgsman, Oscar, additional, Conway, Jordan W, additional, Pires da Silva, Ines, additional, van der Wal, Jacqueline E, additional, Ketelaars, Steven L C, additional, Bresser, Kaspar, additional, Broeks, Annegien, additional, Kerkhoven, Ron M, additional, Reeves, Jason W, additional, Warren, Sarah, additional, Kvistborg, Pia, additional, Scolyer, Richard A, additional, Kapiteijn, Ellen W, additional, Peeper, Daniel S, additional, Long, Georgina V, additional, Schumacher, Ton N M, additional, and Blank, Christian U, additional

Published
2020
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48. Abstract 3412: 36-months and 18-months relapse-free survival after (neo)adjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma patients - update of the OpACIN and OpACIN-neo trials

Author

Blank, Christian U., primary, Versluis, Judith M., additional, Rozeman, Elisa A., additional, Menzies, Alexander M., additional, Reijers, Irene L., additional, Krijgsman, Oscar, additional, Hoefsmit, Esmée P., additional, van de Wiel, Bart A., additional, Sikorska, Karolina, additional, Bierman, Carolien, additional, Dimitriadis, Petros, additional, Gonzalez, Maria, additional, Broeks, Annegien, additional, Kerkhoven, Ron M., additional, Spillane, Andrew J., additional, Haanen, John B., additional, van Houdt, Winan J., additional, Saw, Robyn P., additional, Eriksson, Hanna, additional, van Akkooi, Alexander C., additional, Scolyer, Richard A., additional, Schumacher, Ton N., additional, and Long, Georgina V., additional

Published
2020
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49. Twenty-four months RFS and updated toxicity data from OpACIN-neo: A study to identify the optimal dosing schedule of neoadjuvant ipilimumab (IPI) and nivolumab (NIVO) in stage III melanoma.

Author

Rozeman, Elisa A., primary, Reijers, Irene L.M., additional, Hoefsmit, Esmée P, additional, Sikorska, Karolina, additional, Krijgsman, Oscar, additional, Van De Wiel, Bart A., additional, Dimitriadis, Petros, additional, Eriksson, Hanna, additional, Gonzalez, Maria, additional, Grijpink-Ongering, Lindsay G, additional, Kerkhoven, Ron M., additional, Broeks, Annegien, additional, Klop, Willem M.C., additional, Spillane, Andrew, additional, Saw, Robyn PM, additional, Van Akkooi, Alexander Christopher Jonathan, additional, Scolyer, Richard A., additional, Menzies, Alexander M., additional, Long, Georgina V., additional, and Blank, Christian U., additional

Published
2020
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