853 results on '"Keren G"'
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2. Effect of aluminum hydroxide on serum phosphate and fibroblast growth factor 23 concentrations in young adult cats with surgically induced chronic kidney disease.
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Beita, Keren G., Lourenço, Bianca N., Rehagen, Martina, and Schmiedt, Chad W.
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FIBROBLAST growth factors , *CHRONIC kidney failure , *ALUMINUM hydroxide , *YOUNG adults , *VITAMIN D - Abstract
OBJECTIVE To describe serum fibroblast growth factor 23 (FGF-23) concentrations in young adult cats with remnant kidney model--induced chronic kidney disease (CKD) and to evaluate the effects of orally administered aluminum hydroxide (ALOH) on serum phosphate and FGF-23 concentrations in these cats. ANIMALS 17 adult, purpose-bred cats with induced CKD and 13 healthy, age-matched cats. METHODS A prospective, randomized study. Cats with induced CKD fed a wet renal diet received treatment with ALOH (90 mg/kg/d, PO) on days 0 to 42 and no treatment on days 43 to 84 (treatment group, n = 9) or no treatment on days 0 to 84 (control group, n = 8). Standard serum and urine biochemical analyses and several parameters reflective of calcium-phosphate balance, including serum parathyroid hormone and FGF-23 concentrations, were evaluated at baseline and various time points, including days 42 and 84. Age-matched, healthy, community-owned cats underwent similar evaluations at a single time point. Baseline data from CKD cats were compared to those of healthy cats. Longitudinal data from CKD cats were compared over time. RESULTS Serum phosphate, total and ionized calcium, and FGF-23 concentrations were significantly higher in CKD cats at baseline relative to healthy cats (all P ≤ .009). Serum phosphate concentration did not change significantly over time in either CKD group; however, FGF-23 concentrations significantly increased over time in the control group (P < .02) but not the treatment group (P = .059). CLINICAL RELEVANCE Aluminum hydroxide did not reduce serum phosphate or FGF-23 concentrations in this small study of cats with induced CKD chronically eating a phosphate-restricted diet. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Linear infrastructure impacts on landscape hydrology
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Raiter, Keren G., Prober, Suzanne M., Possingham, Hugh P., Westcott, Fiona, and Hobbs, Richard J.
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- 2018
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4. Exploring client violence during home visits: a qualitative study of perceptions and experiences of Israeli nurses
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Yael Sela, Keren Grinberg, and Inbal Halevi Hochwald
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Client violence ,Home visit ,Nurses ,Organizational support ,Physical violence ,Risk ,Medicine (General) ,R5-920 ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Home care provides an excellent opportunity for personalizing treatment as nurses see patients in their natural environment. Along with its many advantages, the home care environment carries unique risks, as nurses are usually alone, without the protection and security provided by primary care clinics. There are no accurate data in Israel on the scope and characteristics of client violence against nurses during home visits. We conducted a qualitative study to investigate the nature of client violence faced by Israeli nurses during home visits, to gain insights into their perceptions and experiences, and to contribute to the development of effective policies and strategies to combat client violence in the healthcare sector. Methods Twenty-seven female nurses from primary care clinics, who were exposed to client violence during a home visit, were interviewed using a semi-structured interview guide. The interviews were transcribed and analyzed, and categories and themes were extracted. Results Most nurses interviewed experienced at least three incidents of client violence, the most common of which was verbal abuse. The nurses perceived that the location of the encounter between the nurse and the patient in the patient’s natural surroundings, rather than within the controlled boundaries of a clinic, contributes to the risk of violence. Violence affected the nurses’ professional decisions. The nurses reported that their organization had no established guidelines or instructions for safely conducting home visits, they were not provided with protective or security measures for emergencies, nor did they perceive that they had sufficient training to deal with client violence in clients’ homes. Conclusions Nurses encounter a range of challenges that make it difficult for them to deal with client violence during home visits, affecting their personal safety and professional decisions. Their ability to manage such situations is shaped by a complex interplay of personal and organizational factors and requires a range of strategies and resources to effectively address them.
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- 2024
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5. Lines in the sand: quantifying the cumulative development footprint in the world’s largest remaining temperate woodland
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Raiter, Keren G., Prober, Suzanne M., Hobbs, Richard J., and Possingham, Hugh P.
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- 2017
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6. Under the radar: mitigating enigmatic ecological impacts
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Raiter, Keren G., Possingham, Hugh P., Prober, Suzanne M., and Hobbs, Richard J.
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- 2014
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7. A remnant kidney surgery model in cats induces acute and chronic outcomes that mimic spontaneous chronic kidney disease.
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Schmiedt, Chad W., Beita, Keren G., Lourenço, Bianca N., Erickson, Maëva C. M., Herrera, Courtney T., Rissi, Daniel R., Brown, Cathy A., and Brown, Scott A.
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KIDNEYS , *KIDNEY surgery , *CHRONIC kidney failure , *CATS , *ACUTE kidney failure , *KIDNEY diseases - Abstract
OBJECTIVE To report acute and chronic outcomes of cats with chronic kidney disease (CKD) induced by a remnant kidney model. ANIMALS 32 purpose-bred cats (n = 15 female, n = 17 male). PROCEDURES Cats underwent a 2-stage reduction in renal mass through partial arterial ligation of 1 kidney (day 28) and delayed contralateral nephrectomy (day 0), targeting an 11/12th functional nephrectomy. Acute (days -28 - 29) survival and renal function parameters were compared over time, and the latter were evaluated as predictors for acute mortality. Chronic (days 30 to >1,100) survival, renal function, and morphology were described. RESULTS Acutely, renal function deteriorated in all cats (mean ± SD baseline and day 28 serum creatinine mean concentration, 1.13 ± 0.23 mg/dL and 3.03 ± 1.20 mg/dL, respectively; P < .001; and GFR, 3.22 mL/min/kg ± 0.12 and 1.21 mL/min/kg ± 0.08, respectively; P < .001). Seven (22%) cats were euthanized after because of clinical signs of uremia after contralateral nephrectomy. Prenephrectomy renal function tests were not significant indicators for survival during this acute phase. Twenty-five cats entered the chronic phase. Ten cats were euthanized at a median of 163 days from nephrectomy because of progressive renal dysfunction. Median survival times were significantly different when stratified by acute kidney injury grade at day 29. Cats in the chronic phase had clinical courses similar to cats with naturally occurring CKD, and most (13/15) were in CKD stage 2. CLINICAL RELEVANCE The remnant kidney model is effective at reducing kidney function to an extent that mimics important characteristics of spontaneous CKD in cats. [ABSTRACT FROM AUTHOR]
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- 2023
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8. Prevalence of blood type A and risk of vascular complications following transcatheter aortic valve implantation
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Rofe, M.-T., Shacham, Y., Steinvi, A., Barak, L., Hareuveni, M., Banai, S., Keren, G., Finkelstein, A., and Shmilovich, H.
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- 2016
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9. Common Dressing Styles and Attributes Associated with Students’ Dressing Styles in Kenyan Public Universities
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Otieno Gladys Akinyi, Keren G. Mburugu, and Susan Abong’o
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Personal grooming ,Informed choice ,Medical education ,Kenya ,business.industry ,Multiple sampling ,Technical university ,Descriptive survey ,Psychology ,Clothing ,business ,Focus group - Abstract
The study sought to examine students’ dressing styles and common attributes assigned to them. A descriptive survey design was used in this study. The study areas were the University of Nairobi, Egerton University, Moi University, Technical University of Mombasa, Maseno and Karatina Universities. Multiple sampling procedures were used to select 566 students who participated in the study. Data were collected using questionnaires, focus group discussions and observation checklists. Results show that majority of respondents bought their own clothes with funds provided by the parents or guardians. The most outstanding feature that informed choice of dress was aesthetics, followed by comfort and design. Vests, bare chest tops and shorts were considered modest while high-slitted skirts, miniskirts, unbuttoned shirts, boob-tops, tumbo-cuts, skin-tight dresses and trousers and Bermuda shorts were found to be immodest. Recommendations have been made to develop guidelines on the choice of dress for students in institutions of higher learning to enhance personal grooming.
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- 2021
10. Prognostic Awareness, Disease and Palliative Understanding Among Caregivers of Patients With Dementia
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Kaycee M Sink, Jeff D. Williamson, Devin Johnson, Jennifer Gabbard, Keren G. Ferris, Shenita Spencer, Laurie E. McLouth, Mia Yang, Greg Russell, and Gretchen A. Brenes
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Male ,Advance care planning ,Health Knowledge, Attitudes, Practice ,medicine.medical_specialty ,Palliative care ,Disease ,medicine ,Humans ,Dementia ,Intensive care medicine ,Aged ,Aged, 80 and over ,business.industry ,Palliative Care ,Symptom burden ,Cognition ,General Medicine ,Awareness ,Middle Aged ,Prognosis ,medicine.disease ,Cross-Sectional Studies ,Caregivers ,Socioeconomic Factors ,Female ,business - Abstract
Background: Persons with dementia (PwD) often have significant cognitive deficits and functional limitations, requiring substantial caregiver assistance. Given the high symptom burden and terminal nature of dementia, good prognostic awareness and integration of palliative care (PC) is needed. Objective: To evaluate prognostic awareness, disease, and PC understanding among caregivers of PwD and to assess for improvements in routine care. Design: A cross-sectional study of 2 cohorts at a single-academic medical center. Surveys were mailed to 200 caregivers of PwD in 2012 (cohort 1). Surveys were sent to new subset of caregivers of PwD (n = 80) in 2018 (cohort 2) to assess trends over time. Results: A total of 154 of caregivers completed the survey (response rate 55%). Compared to 2012, a higher proportion of caregivers in 2018 reported having conversations about prognosis with PwD’s physicians (25% in 2012 vs 45% in 2018; P = .027). However, a large percentage (43% in 2012 and 40% in 2018) of caregivers reported no understanding of the PwD’s prognosis. Despite most stating dementia was not curable, only 39% in 2012 and 52% in 2018 ( P = .015) understood that dementia was a terminal disease. In addition, only 32% in 2012 and 40% in 2018 ( P = .39) felt that they were knowledgeable about PC. Conclusions: Prognostic discussions between caregivers of PwD and the PwD’s physicians may be occurring more often; however, a high percentage of caregivers report a poor understanding about the terminal nature of dementia and the role of PC.
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- 2019
11. The association between the embolic load and atrial size in acute pulmonary embolism
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AVIRAM, G., STEINVIL, A., BERLINER, S., ROSEN, G., SOSNA, J., MAN, A., KEREN, G., and ROGOWSKI, O.
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- 2011
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12. To behave or not (un)ethically? The meditative effect of mindfulness on statistics anxiety and academic dishonesty moderated by risk aversion
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Yovav Eshet, Keren Grinautsky, and Pnina Steinberger
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Mindfulness ,Statistics anxiety ,Academic dishonesty ,Academic integrity ,Risk aversion ,Theory and practice of education ,LB5-3640 - Abstract
Abstract Despite the growing interest in mindfulness in higher education, the literature on its relation to decision-making under risk (i.e. academic misconduct) and statistics anxiety is scarce. The present research shall fill this gap. Based on the prospect theory, we assessed the mediating effect of mindfulness on the relationship between statistics anxiety and academic dishonesty moderated by risk aversion. Data were collected from 791 undergraduate students in six Israeli academic institutions studying for bachelor’s degrees in social sciences. Questionnaires included the following measures: risk behaviour according to the prospect theory framework, Mindful Attention Awareness Scale, Statistics Anxiety Rating Scale, Academic Misconduct Scale and sociodemographic variables. Correlations among these variables were explored. The data was analysed using Structural Equation Modelling (SEM). The results indicate that the variance in academic dishonesty is explained by students' statistics anxiety with a mediation of Mindfulness moderated by Risk Aversion. Mindfulness negatively affects Academic Dishonesty, while Risk Aversion has a significant positive effect on Mindfulness. Finally, among individuals with high statistics anxiety, Risk Averse individuals show significantly higher Mindfulness than Risk Seekers. We conclude that mindfulness-based interventions might be a constructive tool to reduce risk-taking and promote ethical decision-making among individuals who experience high levels of statistics anxiety. Furthermore, developing mindful skills may help individuals with higher anxiety levels neutralize these unwanted feelings and get along with their learning tasks. Hence, avoid academic unethical behaviours.
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- 2024
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13. Kynurenic acid- a key metabolite protecting the heart from an ischemic damage
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Entin-Meer, M, primary, Bigelman, E B, additional, Pasmanik-Chor, M P C, additional, Dassa, B D, additional, Gross, A G, additional, Itkin, M I, additional, Malitsky, S M, additional, Dorot, O D, additional, Pichinuk, E P, additional, Dezorell, N M, additional, and Keren, G K, additional
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- 2021
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14. Vehicle tracks are predator highways in intact landscapes
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Hugh P. Possingham, Keren G. Raiter, Richard J. Hobbs, Leonie E. Valentine, and Suzanne M. Prober
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0106 biological sciences ,geography ,geography.geographical_feature_category ,biology ,Ecology ,Vegetation ,010603 evolutionary biology ,01 natural sciences ,Predation ,Shrubland ,010601 ecology ,biology.animal ,Threatened species ,Feral cat ,Dingo ,human activities ,Restoration ecology ,Predator ,Ecology, Evolution, Behavior and Systematics ,Nature and Landscape Conservation - Abstract
Roads and other forms of linear infrastructure are rapidly proliferating worldwide, yet little is known about how roads affect the distribution and abundance of predators, particularly in relatively intact landscapes. We used a combination of motion-sensor cameras and spoor surveys to compare dingo, fox and feral cat activity on unsealed vehicle tracks (hereafter: roads) and up to 3 km away, in relatively intact landscapes of the Great Western Woodlands in south-western Australia. We compared predator activity as indicated by independent sightings and spoor observations, in woodlands and shrublands: vegetation types with contrasting permeabilities. Predator activity was observed between 12 and 261 times more frequently on roads compared with off-road for all species studied. Roads also appeared to affect predator activity up to 2.5 km away. Even poorly formed and abandoned roads concentrated predator activity and affected landscape-scale rates of predator observations. The effect of road proximity on predator activity was non-linear and different between vegetation types for dingoes and cats but not foxes. Our results provide new evidence of the effects of roads on predator activity in surrounding landscapes, with interacting effects of vegetation. They also reinforce previous findings e.g. stronger roads preference displayed by dingoes and foxes, than by cats. Roads and other linear infrastructure have strong effects on predator activity within intact landscapes, although further research is needed to characterise the implications for prey species. Road planning or approvals, as well as habitat restoration programs for threatened species, should account for the effects of roads on predator activity.
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- 2018
15. Combined Echocardiographic and Cardiopulmonary Exercise to Assess Determinants of Exercise Limitation in Chronic Obstructive Pulmonary Disease
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Rozenbaum, Z., Ben-Gal, Y., Kapusta, L., Hochstadt, A., Md, B. Sadeh, Md, G. Aviram, Md, O. Havakuk, Md, J. Shimiaie, Md, M. Ghermezi, Laufer-Perl Md, M., Md, Y. Shacham, Keren, G., Topilsky, Y., Rozenbaum, Z., Ben-Gal, Y., Kapusta, L., Hochstadt, A., Md, B. Sadeh, Md, G. Aviram, Md, O. Havakuk, Md, J. Shimiaie, Md, M. Ghermezi, Laufer-Perl Md, M., Md, Y. Shacham, Keren, G., and Topilsky, Y.
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Item does not contain fulltext, BACKGROUND: Current methods do not allow a thorough assessment of causes associated with limited exercise capacity in patients with chronic obstructive pulmonary disease (COPD). METHODS: Twenty patients with COPD and 20 matched control subjects were assessed using combined cardiopulmonary and stress echocardiographic testing. Various echocardiographic parameters (left ventricular [LV] volumes, right ventricular [RV] area, ejection fraction, stroke volume, S', and E/e' ratio) and ventilatory parameters (peak oxygen consumption [Vo(2)] and A-Vo(2) difference) were measured to evaluate LV and RV function, hemodynamics, and peripheral oxygen extraction (A-VO(2) difference). RESULTS: Significant differences (both between groups and for group-by-time interaction) were seen in exercise responses (LV volume, RV area, LV volume/RV area ratio, S', E/e' ratio, tricuspid regurgitation grade, heart rate, stroke volume, and Vo(2)). The major mechanisms of reduced exercise tolerance in patients with COPD were bowing of the septum to the left in 12 (60%), abnormal increases in E/e' ratio in 12 (60%), abnormal stroke volume reserve in 16 (80%), low peak A-Vo(2) difference in 10 (50%), chronotropic incompetence in 13 (65%), or a combination of several mechanisms. Patients with COPD and poor exercise tolerance showed attenuated increases in stroke volume, heart rate, and A-Vo(2) difference and exaggerated changes in LV/RV ratio and LV compliance (ratio of LV volume to E/e' ratio) compared with patients with COPD with good exercise tolerance. CONCLUSIONS: Combined cardiopulmonary and stress echocardiographic testing can be helpful in determining individual mechanisms of exercise intolerance in patients with COPD. In patients with COPD, exercise intolerance is predominantly the result of chronotropic incompetence, limited stroke volume reserve, exercise-induced elevation in left filling pressure, and peripheral factors and not simply obstructive lung function. Limited stroke volume is r
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- 2021
16. MANAGERIAL PERCEPTIONS ON APPAREL FIT MADE WITH PATTERN DRAFTING AND FREE HAND CUTTING TECHNIQUES
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Keren G. Mburugu, Bosibori Oigo, and Dymphna Bakker-Edoh
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Structure (mathematical logic) ,Standardization ,business.industry ,media_common.quotation_subject ,GRASP ,Clothing ,Preference ,Perception ,Respondent ,Apprenticeship ,Marketing ,business ,Psychology ,media_common - Abstract
Purpose: To assess the management perceptions on apparel fit made with pattern drafting and free-hand cutting techniques.Methodology: The study employed a cross-sectional descriptive survey was considered adequate for this study as it has the advantage of soliciting respondent’s views on the nature of the situation as it existed at the time of a study (Creswell, 2012; Mugenda, 2008). The design is an efficient way of collecting information of a large group of people within a short time using questionnaires. The survey design was deemed appropriate for this study as it has the advantage of seeking the views of informal dressmakers and tailors on the use of pattern drafting and free-hand cutting in apparel construction. It allowed for the use of both quantitative and qualitative techniques in the study. This paved way for better understanding of a phenomenon under study. The use of these methods offered the opportunity to have in-depth information and also the weakness in one method is compensated for by the strength in another method (Creswell, 2012).Results: The results revealed that dressmakers and tailors’ preference to free-hand cutting was influenced by the method they were trained with. Additionally, standardization of apparel production among the members can best be achieved by intensifying the use of pattern drafting as part of apprenticeship training to ensure accuracy in fit among informal dressmakers and tailors locally. The respondents were asked to state their views on whether educational level hinders the progress of their training.Unique Contribution to theory, practice and policy: Reason why informal dressmakers and tailors were not using pattern drafting in apprenticeship training might be related to the fact that pattern skills seemed too difficult to understand and the period of training might be short to grasp the details of the method. Taking their educational level and period of training into consideration, it would be very difficult for the apprentices to cope with the contents that come with patterns. This implies that, there is the need to inculcate the use of pattern drafting as part of training curriculum of apprentices and also increase the period of training to allow both masters and apprentices gain better grasp of the pattern drafting skills. When trainees are given adequate training skills on the use of pattern drafting, they would improve and this would in effect manifest in the high standard on fit of apparel among the dressmakers and tailors in the informal setting in the near future. The study recommended future studies to focus on the factors influencing training and acquisition of both skills of apparel constructions. This will help the policy makers rectify the structure of education accordingly to improve the way skills are disseminated and executed.
- Published
- 2018
17. Advance care planning for vulnerable older adults within an Accountable Care Organization: study protocol for the IMPACT randomised controlled trial
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Carl Grey, Adam Moses, Kristie L. Foley, Ajay Dharod, Jeff D. Williamson, Nicholas M. Pajewski, Jennifer Gabbard, Kathryn E. Callahan, and Keren G. Ferris
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Advance care planning ,Decision Making ,advance care directives ,Context (language use) ,Documentation ,law.invention ,03 medical and health sciences ,Advance Care Planning ,0302 clinical medicine ,Randomized controlled trial ,Nursing ,law ,Intervention (counseling) ,Health care ,Pragmatic Clinical Trials as Topic ,Protocol ,Medicine ,Humans ,Multicenter Studies as Topic ,end of life care ,030212 general & internal medicine ,Aged ,Terminal Care ,Accountable Care Organizations ,business.industry ,Palliative Care ,goals of care ,General Medicine ,electronic health record ,3. Good health ,Informatics ,Chronic Disease ,Patient Participation ,business ,End-of-life care ,030217 neurology & neurosurgery - Abstract
IntroductionPatients with multimorbidity plus additional impairments (eg, mobility limitations, disability, cognitive impairments or frailty) are at the highest risk for poor healthcare outcomes. Advanced care planning (ACP) provides patients and their surrogates the opportunity to discuss their goals, values and priorities for healthcare—particularly in the context of end-of-life care. ACP discussions promote more person-centred care; however, it is currently underused. There is a tremendous need for systematic, scalable approaches to individualised ACP that promotes patient and family engagement. Here we describe the study protocol for a randomised effectiveness trial of a nurse navigator and informatics intervention designed to improve the documentation and quality of ACP discussions.Methods and analysisThis is a randomised, pragmatic, effectiveness trial; patients aged 65 years and older who have multimorbidity plus impairments in either physical function (eg, mobility limitations or disability) or cognition, and/or frailty within an affiliated Accountable Care Organization were eligible. The electronic health record was used to develop an automatic prescreening system for eligible patients (n=765) and participants were randomised in a 1:1 ratio to either the nurse navigator-led ACP pathway or usual care. Our primary outcomes are documentation of ACP discussions within the EHR along with the quality of ACP discussions. Secondary outcomes include a broad range of ACP actions (eg, usage of ACP billing codes, choosing a surrogate decision-maker and advance directive documentation). Outcomes will be measured over 12 months of follow-up.Ethics and disseminationThis study has been approved by the appropriate Institutional Review Boards and is guided by input from patient and clinical advisory boards. The results of this study will inform a scalable solution to ACP discussions throughout our healthcare system and statewide.Trials registration numberNCT03609658.
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- 2019
18. The state of leukocyte adhesiveness/aggregation in the peripheral blood of patients with type 2 diabetes and ischemic vascular disease
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Fusman, R., Rotstein, R., Zeltser, D., Prochorov, V., Shapira, I., Bornstein, N.M., Keren, G., Roth, A., Miller, H.I., Avitzour, D., Arber, N., and Berliner, S.
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- 2001
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19. Caregivers' Understanding of the Terminal Nature of Dementia Survey
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Gabbard, Jennifer, primary, Johnson, Devin, additional, Russell, Greg, additional, Spencer, Shenita, additional, Williamson, Jeff D., additional, McLouth, Laurie E., additional, Ferris, Keren G., additional, Sink, Kaycee, additional, Brenes, Gretchen, additional, and Yang, Mia, additional
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- 2020
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20. Prognostic Awareness, Disease and Palliative Understanding Among Caregivers of Patients With Dementia
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Gabbard, Jennifer, primary, Johnson, Devin, additional, Russell, Greg, additional, Spencer, Shenita, additional, Williamson, Jeff D., additional, McLouth, Laurie E., additional, Ferris, Keren G., additional, Sink, Kaycee, additional, Brenes, Gretchen, additional, and Yang, Mia, additional
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- 2019
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21. High-Dose Intravenous γ-Globulins for Heparin-Induced Thrombocytopenia: A Prompt Response
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Winder, A., Shoenfeld, Y., Hochman, R., Keren, G., Levy, Y., and Eldor, A.
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- 1998
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22. Lines in the sand: quantifying the cumulative development footprint in the world’s largest remaining temperate woodland
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Keren G. Raiter, Hugh P. Possingham, Suzanne M. Prober, and Richard J. Hobbs
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0106 biological sciences ,Sustainable development ,010504 meteorology & atmospheric sciences ,Ecology ,business.industry ,Geography, Planning and Development ,Road ecology ,Environmental resource management ,Cumulative effects ,Landscape conservation ,Woodland ,010603 evolutionary biology ,01 natural sciences ,Aerial imagery ,Footprint ,Environmental science ,Landscape ecology ,business ,0105 earth and related environmental sciences ,Nature and Landscape Conservation - Abstract
The acceleration of infrastructure development presents many challenges for the mitigation of ecological impacts. The type, extent, and cumulative effects of multiple developments must be quantified to enable mitigation. We quantified anthropogenic development footprints in a globally significant and relatively intact region. We identified the proportion accounted for by linear infrastructure (e.g. roads) including infrastructure that is currently unmapped; investigated the importance of key landscape drivers; and explored potential ramifications of offsite impacts (edge effects). We quantified direct development footprints of linear and ‘hub’ infrastructure in the Great Western Woodlands (GWW) in south-western Australia, using digitisation and extrapolation from a stratified random sample of aerial imagery. We used spatial datasets and literature resources to identify predictors of development footprint extent and calculate hypothetical ‘edge effect zones’. Unmapped linear infrastructure, only detectable through manual digitisation, accounts for the greatest proportion of the direct development footprint. Across the 160,000 km2 GWW, the estimated development footprint is 690 km2, of which 67% consists of linear infrastructure and the remainder is ‘hub’ infrastructure. An estimated 150,000 km of linear infrastructure exists in the study area, equating to an average of ~1 km per km2. Beyond the direct footprint, a further 4000–55,000 km2 (3–35% of the region) lies within edge effect zones. This study highlights the pervasiveness of linear infrastructure and hence the importance of managing its cumulative impacts as a key component of landscape conservation. Our methodology can be applied to other relatively intact landscapes worldwide.
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- 2017
23. Cepstrum analysis of reflected pressure waves in stenosed arteries
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Roffeh, Y., Einav, S., Liaw, J., Whiting, J., and Keren, G.
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- 1996
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24. Effectiveness of a Nurse-Led Multidisciplinary Intervention vs Usual Care on Advance Care Planning for Vulnerable Older Adults in an Accountable Care Organization
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Ajay Dharod, Jeff D Williamson, Keren G. Ferris, Kathryn E. Callahan, Nicholas M. Pajewski, Adam Moses, James J Willard, Kristie L. Foley, and Jennifer Gabbard
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Male ,Advance care planning ,medicine.medical_specialty ,Surrogate decision-maker ,MEDLINE ,Psychological intervention ,Vulnerable Populations ,01 natural sciences ,law.invention ,Advance Care Planning ,03 medical and health sciences ,0302 clinical medicine ,Documentation ,Randomized controlled trial ,Informed consent ,law ,Health care ,Internal Medicine ,medicine ,Electronic Health Records ,Humans ,Patient Navigation ,030212 general & internal medicine ,0101 mathematics ,Aged ,Aged, 80 and over ,Patient Care Team ,Accountable Care Organizations ,business.industry ,010102 general mathematics ,humanities ,Family medicine ,Female ,business - Abstract
Advance care planning (ACP), especially among vulnerable older adults, remains underused in primary care. Additionally, many ACP initiatives fail to integrate directly into the electronic health record (EHR), resulting in infrequent and disorganized documentation.To determine whether a nurse navigator-led ACP pathway combined with a health care professional-facing EHR interface improves the occurrence of ACP discussions and their documentation within the EHR.This was a randomized effectiveness trial using the Zelen design, in which patients are randomized prior to informed consent, with only those randomized to the intervention subsequently approached to provide informed consent. Randomization began November 1, 2018, and follow-up concluded November 1, 2019. The study population included patients 65 years or older with multimorbidity combined with either cognitive or physical impairments, and/or frailty, assessed from 8 primary care practices in North Carolina.Participants were randomized to either a nurse navigator-led ACP pathway (n = 379) or usual care (n = 380).The primary outcome was documentation of a new ACP discussion within the EHR. Secondary outcomes included the usage of ACP billing codes, designation of a surrogate decision maker, and ACP legal form documentation. Exploratory outcomes included incident health care use.Among 759 randomized patients (mean age 77.7 years, 455 women [59.9%]), the nurse navigator-led ACP pathway resulted in a higher rate of ACP documentation (42.2% vs 3.7%, P .001) as compared with usual care. The ACP billing codes were used more frequently for patients randomized to the nurse navigator-led ACP pathway (25.3% vs 1.3%, P .001). Patients randomized to the nurse navigator-led ACP pathway more frequently designated a surrogate decision maker (64% vs 35%, P .001) and completed ACP legal forms (24.3% vs 10.0%, P .001). During follow-up, the incidence of emergency department visits and inpatient hospitalizations was similar between the randomized groups (hazard ratio, 1.17; 95% CI, 0.92-1.50).A nurse navigator-led ACP pathway integrated with a health care professional-facing EHR interface increased the frequency of ACP discussions and their documentation. Additional research will be required to evaluate whether increased EHR documentation leads to improvements in goal-concordant care.ClinicalTrials.gov Identifier: NCT03609658.
- Published
- 2021
25. Circulating adiponectin concentrations in patients with congestive heart failure
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George, J, Patal, S, Wexler, D, Sharabi, Y, Peleg, E, Kamari, Y, Grossman, E, Sheps, D, Keren, G, and Roth, A
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- 2006
26. Assessing Mental Health Conditions in Women with Gestational Diabetes Compared to Healthy Pregnant Women
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Keren Grinberg and Yael Yisaschar-Mekuzas
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gestational diabetes mellitus (GDM) ,anxiety ,distress ,depression ,somatization ,Medicine - Abstract
Introduction: Pregnant women with gestational diabetes mellitus (GDM) experience higher psychological stress levels than healthy pregnant women. The objectives of the current study were to examine (1) the differences in anxiety, depression, stress, and somatization levels between women diagnosed with GDM and healthy pregnant women, and (2) the differences in anxiety, depression, stress, and somatization levels among women with well-controlled blood sugar levels compared to those who are not well controlled. Methods: A quantitative cross-sectional study was conducted, involving 103 women who had been pregnant at least once, including 40 women diagnosed with GDM and 63 healthy pregnant women. An online questionnaire was distributed that included three parts: socio-demographic parameters, the DASS-21 questionnaire assessing anxiety, depression, and stress, and the Brief Symptom Inventory (BSI) questionnaire assessing somatization. Results: Differences in the anxiety (t = 14.470, p < 0.05), depression (t(38) = −2.88, p < 0.01), stress (t(38) = −1.88, p < 0.05), and somatization (t(38) = −1.88, p < 0.05) levels compared to women with poorer blood sugar control. Conclusions: Pregnant women diagnosed with GDM report higher levels of negative mental health conditions such as anxiety, depression, stress, and somatization compared to healthy pregnant women.
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- 2024
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27. Impact of right ventricular dysfunction and end-diastolic pulmonary artery pressure estimated from analysis of tricuspid regurgitant velocity spectrum in patients with preserved ejection fraction
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Baruch, G., Rothschild, E., Kapusta, L., Schwartz, L.A., Biner, S., Aviram, G., Ingbir, M., Nachmany, I., Keren, G., Topilsky, Y., Baruch, G., Rothschild, E., Kapusta, L., Schwartz, L.A., Biner, S., Aviram, G., Ingbir, M., Nachmany, I., Keren, G., and Topilsky, Y.
- Abstract
Item does not contain fulltext, AIMS: We aimed to analyse the association between right haemodynamic parameters, right ventricular (RV) dysfunction parameters, and outcomes in patients with preserved ejection fraction (EF). METHODS AND RESULTS: Retrospective analysis of right haemodynamic (systolic pulmonary pressure and end-diastolic pulmonary pressure based on tricuspid regurgitation (TR) velocity at pulmonary valve opening time), and RV parameters including size (end-diastolic and end-systolic area), function (RV fractional area change, Tei index, Tricuspid Annular Plane Systolic Excursion, and speckle tracking derived free wall strain), from 557 consecutive patients with preserved EF [EF >/= 50%; age 64.9 + 20; 52% female; co-morbidity Charlson index 4.7 (2.9, 6.4)]. All cause and cardiac mortality were retrospectively analysed and correlated to echo haemodynamic and co-morbid parameters. TR velocity at pulmonary valve opening time and calculated end-diastolic pulmonary artery pressure were obtainable in 71% of patients. The best haemodynamic univariate predictor of mortality was calculated end-diastolic pulmonary artery pressure [hazard ratio 1.06 (1.04-1.07); P < 0.0001], superior to TR peak velocity and systolic pulmonary artery pressure. Elevated end-diastolic pulmonary artery pressure was associated with all cause and cardiac mortality even when adjusted for all significant clinical (age, gender, and Charlson index), and echo (stroke volume index, left atrial volume index, systolic pulmonary pressure, E/e', and Tei index) parameters. Tei index was superior to all other RV functional parameters (P < 0.05 for all parameters). CONCLUSION: TR velocity at pulmonary valve opening time and calculated end-diastolic pulmonary artery pressure are obtainable in most patients, and add prognostic information on top of clinical and routine haemodynamic and diastolic parameters.
- Published
- 2019
28. Relation of preexisting anti-β2GPI antibodies to infarct size in a rat model
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Barshack, I., Keren, P., Goldberg, I., Kopolovic, J., Keren, G., and George, J.
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- 2003
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29. Vehicle tracks are predator highways in intact landscapes
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Raiter, Keren G., primary, Hobbs, Richard J., additional, Possingham, Hugh P., additional, Valentine, Leonie E., additional, and Prober, Suzanne M., additional
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- 2018
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30. Ventriculitis caused byKlebsiella pneumoniae successfully treated with pefloxacin in a neonate
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Linder, Nehama, Kuint, J., Reichman, B., Keler, N., Keren, G., and Dagan, R.
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- 1994
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31. Clear consideration of costs, condition and conservation benefits yields better planning outcomes
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Keren G. Raiter, Megan C. Evans, Kerrie A. Wilson, Elizabeth A. Law, Ayesha I. T. Tulloch, and Hugh P. Possingham
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Cost–benefit analysis ,business.industry ,Decision theory ,Environmental resource management ,Environmental restoration ,Woodland ,Conditionality ,Intervention (law) ,Marxan ,Business ,Restoration ecology ,Environmental planning ,Ecology, Evolution, Behavior and Systematics ,Nature and Landscape Conservation - Abstract
The conservation benefit of a management action depends on what would have happened in the absence of an intervention, and whether the conservation objective is to maintain the existing biodiversity values, or to restore those that have been lost. How this benefit is calculated and considered in spatial prioritisation analyses could influence the expected cost-effectiveness of management, although this has not previously been explored. Here, we use a comprehensive decision theoretic approach to identify management priorities in a region of ecological, cultural and economic significance, the Great Western Woodlands (GWW) of south-western Australia. To demonstrate how cost, condition and conservation benefits affect prioritisation outcomes, we consider two different conservation objectives: the maintenance of native vegetation communities and the restoration of natural fire regimes. We compare the results from (1) our comprehensive approach, to priorities identified using two alternative approaches: (2) consider generic management costs (travel, labour) and assume that landscape condition is homogenous or (3) use landscape condition as a surrogate for the cost of management, i.e. areas in poor condition are assumed to have high costs. We demonstrate that prioritisation outcomes differ substantially depending on how the benefits and costs of a management action are calculated. Using landscape condition as a surrogate for management costs resulted in priority areas that were least cost-effective. To avoid misspent conservation funding, we argue that care must be taken to incorporate the most appropriate cost and condition metrics into spatial prioritisation analyses, and that conservation benefits must be derived from a clearly specified objective.
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- 2015
32. Medical decision making
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Stiggelbout, A.M., Vries, M. de, Scherer, L., Keren, G., Wu, G., Keren, G., and Wu, G.
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Behaviour Change and Well-being ,Management science ,Medical decision making ,Psychology - Abstract
Item does not contain fulltext This chapter presents an overview of the field of medical decision making. It distinguishes the levels of decision making seen in health-care practice and shows how research in judgment and decision making support or improve decision making. Most of the research has been done at the micro level, particularly the research on biases and heuristics. One way to improve medical decisions is to incorporate effective debiasing strategies or manipulations into them. The chapter discusses the framing of risks and the role of affect that has gained more attention in medical decision making in recent years. Next it highlights that eliciting judgments from the general public may entail problems related to affective forecasting. The chapter discusses the finding that judgments one makes for oneself seem to be different from those one makes for others. Finally, it talks about the implementation of prevention programs and topics of health literacy and numeracy.
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- 2016
33. Neurosciences contribution to judgment and decision making: Opportunities and limitations
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Sanfey, A.G., Stallen, M., Keren, G., Wu, G., Keren, G., and Wu, G.
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Behaviour Change and Well-being ,140 000 Decision neuroscience - Abstract
Item does not contain fulltext
- Published
- 2016
34. Phenotypic and mtDNA variation in Philippine Kappaphycus cottonii (Gigartinales, Rhodophyta)
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Richard V. Dumilag, Christian Philip C Garcia, Lance Agahan, William George M Gallardo, YeaEun You, and Alyssa Keren G Chaves
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0106 biological sciences ,0301 basic medicine ,Genetic Speciation ,Lineage (evolution) ,Biology ,01 natural sciences ,DNA, Mitochondrial ,Electron Transport Complex IV ,03 medical and health sciences ,Genus ,Genetic variation ,Genetics ,Genetic variability ,Molecular Biology ,Phylogeny ,Plant Proteins ,Genetic diversity ,Polymorphism, Genetic ,Phylogenetic tree ,010604 marine biology & hydrobiology ,Kappaphycus ,biology.organism_classification ,030104 developmental biology ,Phenotype ,Haplotypes ,Evolutionary biology ,Rhodophyta ,Gigartinales - Abstract
Members of the carrageenan-producing seaweeds of the genus Kappapphycus have a complicated taxonomic history particularly with regard to species identification. Many taxonomic challenges in this group have been currently addressed with the use of mtDNA sequences. The phylogenetic status and genetic diversity of one of the lesser known species, Kappaphycus cottonii, have repeatedly come into question. This study explored the genetic variation in Philippine K. cottonii using the mtDNA COI-5P gene and cox2-3 spacer sequences. The six phenotypic forms in K. cottonii did not correspond to the observed genetic variability; hinting at the greater involvement of environmental factors in determining changes to the morphology of this alga. Our results revealed that the Philippine K. cottonii has the richest number of haplotypes that have been detected, so far, for any Kappaphycus species. Our inferred phylogenetic trees suggested two lineages: a lineage, which exclusively includes K. cottonii and another lineage comprising the four known Kappaphycus species: K. alvarezii, K. inermis, K. malesianus, and K. striatus. The dichotomy supports the apparent synamorphy for each of these lineages (the strictly terete thalli, lack of protuberances, and the presence of a hyphal central core in the latter group, while the opposite of these morphologies in K. cottonii). These findings shed new light on understanding the evolutionary history of the genus. Assessing the breadth of the phenotypic and genetic variation in K. cottonii has implications for the conservation and management of the overall Kappaphycus genetic resources, especially in the Philippines.
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- 2017
35. Cost effectiveness of home care versus hospital care: a retrospective analysis
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Iris Megido, Yael Sela, and Keren Grinberg
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Medicine (General) ,R5-920 - Abstract
Abstract Background Increased utilization of health services due to population growth affects the allocation of national resources and budgets. Hence, it is important for national policy. Home hospitalization is one of the solutions for dealing with the growing demand for hospital beds and reducing the duration of hospitalization and its costs. It is gradually becoming part of the regular care in many health systems, yet, studies on the economic aspects of Community-Based Home Hospitalization (CBHH) implementation in Israel are few. The aim of this study is to examine costs of CBHH in comparison to costs of inpatient hospital care in the Israeli public health system. Methods Retrospective data was collected using document research in databases. A review of the costs of patients in CBHH at Maccabi Healthcare Services (MHS) was conducted. A total of 3374 patients were included in this study: 1687 patients who were in CBHH, and 1687 age- and sex-matched patients who were hospitalized in an internal department (the control group). The study population included the patients admitted to CBHH from January 2018 to July 2020, and patients admitted to internal medicine departments during the same period. Results The number of hospitalizations during the follow up period were statistically significantly lower in the CBHH group compared with the control group (M = 1.18, SD = 0.56 vs. M = 1.61, SD = 1.29, p
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- 2023
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36. Not All Memories Created Equal: Dynamic User Representations for Collaborative Filtering
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Keren Gaiger, Oren Barkan, Shir Tsipory-Samuel, and Noam Koenigstein
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Artificial neural networks ,collaborative filtering ,neural attention ,recommender systems ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
Collaborative filtering methods for recommender systems tend to represent users as a single static latent vector. However, user behavior and interests may dynamically change in the context of the recommended item being presented to the user. For example, in the case of movie recommendations, it is usually true that movies that the user watched more recently are more informative than movies that were watched a long time ago. However, it is possible that a particular movie from the past may become suddenly more relevant for prediction in the presence of a recommendation for its sequel movie. In response to this issue, we introduce the Attentive Item2Vec++ (AI2V++) model, a neural attentive collaborative filtering approach in which the user representation adapts dynamically in the presence of the recommended item. AI2V++ employs a novel context-target attention mechanism in order to learn and capture different characteristics of the user’s historical behavior with respect to a potential recommended item. Furthermore, analysis of the neural-attentive scores allows for improved interpretability and explainability of the model. We evaluate our proposed approach on five publicly available datasets and demonstrate its superior performance in comparison to state-of-the-art baselines across multiple accuracy metrics.
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- 2023
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37. Under the radar: mitigating enigmatic ecological impacts
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Keren G. Raiter, Suzanne M. Prober, Hugh P. Possingham, and Richard J. Hobbs
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Conservation of Natural Resources ,Ecology ,business.industry ,Environmental resource management ,Slip (materials science) ,Environment ,Urban expansion ,law.invention ,law ,Environmental science ,Radar ,business ,Ecology, Evolution, Behavior and Systematics ,Impact mitigation - Abstract
Identifying the deleterious ecological effects of developments, such as roads, mining, and urban expansion, is essential for informing development decisions and identifying appropriate mitigation actions. However, there are many types of ecological impacts that slip 'under the radar' of conventional impact evaluations and undermine the potential for successful impact mitigation (including offsets). These 'enigmatic' impacts include those that are small but act cumulatively; those outside of the area directly considered in the evaluation; those not detectable with the methods, paradigms, or spatiotemporal scales used to detect them; those facilitated, but not directly caused, by development; and synergistic impact interactions. Here, we propose a framework for conceptualising enigmatic impacts and discuss ways to address them.
- Published
- 2014
38. Fashion marketing: Strategies in the garment-making micro and small enterprises in Nakuru, Kenya
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MilcahMulu-Mutuku, Keren G. Mburugu, and Lydia N. Kinuthia
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Return on marketing investment ,Business-to-government ,Marketing management ,Digital marketing ,business.industry ,Marketing ,business ,Marketing research ,Marketing strategy ,Marketing mix ,Relationship marketing ,Industrial and Manufacturing Engineering - Abstract
Fashion is very dynamic and way of life for humans in many consumer products, clothing included. In Kenya, the clothing industry is characterized by a dynamic environment and intense competition caused mainly by enlarged globalization, trade liberalization and importation of second-hand (mitumba) clothes. In this kind of environment, it is becoming increasingly difficult for an enterprise to maintain long-term success. Thus, the clothing enterprises are faced with challenges that demand them to offer higher value added products that meet the demands of the customers. As a solution, sound marketing strategies are critical to the survival and growth of micro-enterprises in the garment making sector. However, there is limited research that has looked at the enterprises from a marketing strategy perspective in terms of the type of marketing strategies that are embraced. This paper aims at highlighting the various marketing strategies. The study used ex-post facto research design targeting garment-making micro-enterprises with less than ten employees in Nakuru town. The main data collection instrument was a questionnaire that comprised closed and open-ended questions. Principal component analysis and Chi-square goodness-of-fit test (x2) were used to determine the various marketing strategies and test the hypothesis that there was no variation in the marketing strategies implemented by garment-making micro-enterprises. Eight strategies were identified as being implemented by garment-making micro-enterprises. Based on the results of this study, it is concluded that interactive marketing is the most implemented strategy while e-marketing is the least. However, further research is required to explore the impact of implementing the various marketing strategies on the growth of the enterprises. Key words: Garment-making, micro and small enterprises, marketing strategies.
- Published
- 2014
39. Prognostic Awareness, Disease and Palliative Understanding Among Caregivers of Patients With Dementia.
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Gabbard, Jennifer, Johnson, Devin, Russell, Greg, Spencer, Shenita, Williamson, Jeff D., McLouth, Laurie E., Ferris, Keren G., Sink, Kaycee, Brenes, Gretchen, and Yang, Mia
- Abstract
Background: Persons with dementia (PwD) often have significant cognitive deficits and functional limitations, requiring substantial caregiver assistance. Given the high symptom burden and terminal nature of dementia, good prognostic awareness and integration of palliative care (PC) is needed. Objective: To evaluate prognostic awareness, disease, and PC understanding among caregivers of PwD and to assess for improvements in routine care. Design: A cross-sectional study of 2 cohorts at a single-academic medical center. Surveys were mailed to 200 caregivers of PwD in 2012 (cohort 1). Surveys were sent to new subset of caregivers of PwD (n = 80) in 2018 (cohort 2) to assess trends over time. Results: A total of 154 of caregivers completed the survey (response rate 55%). Compared to 2012, a higher proportion of caregivers in 2018 reported having conversations about prognosis with PwD's physicians (25% in 2012 vs 45% in 2018; P =.027). However, a large percentage (43% in 2012 and 40% in 2018) of caregivers reported no understanding of the PwD's prognosis. Despite most stating dementia was not curable, only 39% in 2012 and 52% in 2018 (P =.015) understood that dementia was a terminal disease. In addition, only 32% in 2012 and 40% in 2018 (P =.39) felt that they were knowledgeable about PC. Conclusions: Prognostic discussions between caregivers of PwD and the PwD's physicians may be occurring more often; however, a high percentage of caregivers report a poor understanding about the terminal nature of dementia and the role of PC. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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40. MANAGERIAL PERCEPTIONS ON APPAREL FIT MADE WITH PATTERN DRAFTING AND FREE HAND CUTTING TECHNIQUES
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Bakker-Edoh, Dymphna, primary, Oigo, Dr. Bosibori, additional, and Mburugu, Prof. Keren G., additional
- Published
- 2018
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41. P2821Specific MMP-9 and MMP-2 inhibition by novel MMP antibody attenuates LV remodeling secondary to volume overload
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Cohen, L, primary, Bigelman, E, additional, Sagi, I, additional, Keren, G, additional, and Entin-Meer, M, additional
- Published
- 2018
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42. P4603Incidence, characteristics, possible pathogenesis and outcomes in very young patients with ST segment elevation myocardial infarction
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Khoury, S, primary, Soleman, M, additional, Margolis, G, additional, Keren, G, additional, and Shacham, Y, additional
- Published
- 2018
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43. Does statistics anxiety impact academic dishonesty? Academic challenges in the age of distance learning
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Yovav Eshet, Pnina Steinberger, and Keren Grinautsky
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Academic dishonesty ,Statistics anxiety ,Personality traits ,Learning Environment ,Motivation ,Theory and practice of education ,LB5-3640 - Abstract
Abstract This study discusses the mediating role of statistics anxiety and motivation in the relationship comprising academic dishonesty, personality traits, and previous academic achievements in three different learning environments (Face to Face -F2F, Planned Online Environment – POE, and Emergency Remote Teaching – ERT). Self-determination theory (SDT) provides a broad psychological framework for these phenomena. Data were collected from 649 bachelor-degree students in the Social Sciences in five Israeli academic institutions. Structural equation modelling was employed to investigate the research variables’ relationships. Findings indicate that statistics anxiety mediates the relationship between personality traits and academic dishonesty in the POE and the ERT learning environments. Findings also indicate the relationship between students’ achievements and academic dishonesty, but only in the ERT learning environment. In contrast, motivation mediates the relationship between students’ achievements and statistics anxiety only in the POE learning environment. This study unveils that learning environments determine the mediating role of statistical anxiety. In digital learning environments (POE, ERT), mediation has been found between students’ personality traits and academic dishonesty. No similar parallel mediation could be established in the physical learning environment, F2F. Thus, we conclude that online courses should be designed according to student-centred approaches.
- Published
- 2022
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44. Relationship between cognitive function in individuals with diabetic foot ulcer and mortality
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Yael Sela, Keren Grinberg, Tali Cukierman-Yaffe, and Rachel Natovich
- Subjects
Diabetes mellitus ,Mortality ,Cognitive dysfunction ,Diabetic foot ulcer ,Cognitive tests ,Nutritional diseases. Deficiency diseases ,RC620-627 - Abstract
Abstract Background Diabetic foot ulcer (DFU) is a common diabetes mellitus (DM) complication. Individuals with DM and a DFU achieved significantly lower scores in cognitive tests than those without a DFU. We investigated whether baseline cognitive function in individuals with a DFU is a determinant of mortality. Methods A prospective study using data collected during a case–control study conducted in 2010–2012 whereby 90 participants with a DFU (mean age at baseline 58.28 ± 6.95 years, 75.6% male) took the paper and pencil and the NeuroTrax battery of cognitive tests. Depression was assessed, and the DFU status was evaluated. In 2020, information pertaining to participants’ vital status (dead/alive) was collected and the relationship between baseline cognitive status and vital status was assessed. Results During a median follow-up of 6.8 years (range 0.2–9.5), 39 participants died (43.3%). Individuals alive vs. those who had died during follow-up had a higher global cognitive score at baseline (92.16 ± 10.95 vs. 87.18 ± 12.24, p = 0.045), but increased risk was not found. Individuals who were alive vs. those who had died during follow-up had statistically significantly higher baseline executive function, reaction time and digit symbol substitution test results. However, after adjustment for glycosylated hemoglobin (HbA1c), microvascular and macrovascular complications, no relationship between cognitive tests and mortality remained significant. Conclusions The higher mortality rate among people with type 2 DM and a DFU was not significant after adjustment for HbA1c, micro- and macrovascular complications. There may be common pathophysiological pathways to both DM complications and cognitive impairment, which may contribute to increased mortality. Further studies are warranted.
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- 2022
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45. Raised Plasma Renin Activity In The Hypertension Of The Guillain-Barré Syndrome
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Laufer, J., Passwell, J., Keren, G., Brandt, N., and Cohen, B. E.
- Published
- 1981
46. Editorial: Highlights in psychology for clinical settings: the ascent of digital psychotherapy
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Moshe Bensimon, Meyran Boniel-Nissim, Vera Békés, Eamonn Patrick Arble, and Keren Gueta
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digital psychotherapy ,telepsychotherapy ,remote psychotherapy ,online therapy ,videoconferencing psychotherapy ,telemental health ,Psychology ,BF1-990 - Published
- 2023
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47. Editorial: Men who experience interpersonal violence: perspectives from research to intervention
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Keren Gueta and Anat Ben-Porat
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sexual abuse ,intimate partner violence ,masculinities ,victimization ,gender ,Psychology ,BF1-990 - Published
- 2023
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48. Cultural accommodation of internet-based interventions for substance use and related disorders: a proposed comprehensive framework based on a pilot study and a literature review
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Keren Gueta, Yossi Harel-Fisch, and Sophie D. Walsh
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substance use and related disorders ,cultural accommodation ,internet-delivered treatment ,intersectionality ,remote psychotherapy ,Psychology ,BF1-990 - Abstract
Despite the low utilization rates of substance use and related disorders services, and the ability of internet-based interventions for substance use and related disorders (IBIS) to address challenges related to service engagement, limited attention has been placed on the processes for the accommodation of these interventions to diverse cultural settings. This study aimed to develop a framework for the cultural accommodation of IBIS across populations based on a pilot study and a literature review. A pilot study of cultural accommodation of an existing internet intervention for alcohol use was carried out in Israel, which involved focus groups and daily online surveys of prospective consumers (N = 24) as well as interviews with experts (N = 7) in the substance abuse treatment field. Thematic analysis revealed a range of themes that relate to the general Israeli culture and the specific Israeli drinking subculture, identified as needing to be addressed in the process of intervention accommodation. A comprehensive framework for cultural accommodation of IBIS is suggested, consisting of five stages: Technical and cultural feasibility; Engagement of target group; Identification of accommodation variables, Accommodation, and evaluation of the accommodated intervention. In addition, the framework consists of four dimensions of accommodation: Barriers and facilitators; Audio-visual materials and language; Mechanisms of change; Intersectional factors. We suggest that the proposed framework may serve as a guide for the cultural accommodation of existing internet-based interventions for substance use and related disorders across a range of cultural and geographical settings, thus augmenting the ecological validity of internet-based interventions for substance use and related disorders, expanding cross-cultural intervention research, and reducing health disparities worldwide.
- Published
- 2023
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49. 10-year stroke prevention after successful carotid endarterectomy for asymptomatic stenosis (ACST-1): a multicentre randomised trial
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Halliday, A, Harrison, M, Hayter, E, Kong, X, Mansfield, A, Marro, J, Pan, H, Peto, R, Potter, J, Rahimi, K, Rau, A, Robertson, S, Streifler, J, Thomas, D, Fraedrich G, Asymptomatic Carotid Surgery Trial Collaborative G. r. o. u. p., Schmidauer, C, Hölzenbein, Th, Huk, I, Haumer, M, Kretschmer, G, Metz, V, Polterauer, P, Teufelsbauer, H, Cras, P, Hendriks, J, Lauwers, P, Van Schil, P, de Souza EB, Dourado, Me, Gurgel, G, Rocha, Gm, Petrov, V, Slabakov, G, Cooper, Me, Gubitz, G, Holness, R, Howes, W, Langille, R, Legg, K, Nearing, S, Mackean, G, Mackay, M, Phillips, Sj, Sullivan, J, Wood, J, Erdelez, L, Sosa, T, Angelides, Ns, Christopoulos, G, Malikidou, A, Pesta, A, Ambler, Z, Mracek, J, Polivka, J, Rohan, V, Sevcik, P, Simaná, J, Benes, V, Kramár, F, Kaste, M, Lepäntalo, M, Soinne, L, Cardon, Jm, Legalou, A, Gengenbach, B, Pfadenhauer, K, Wölfl, Kd, Flessenkämper, I, Klumpp, Bf, Marsch, J, Kolvenbach, R, Pfeiff, T, Sandmann, W, Beyersdorf, F, Hetzel, A, Sarai, K, Schöllhorn, J, Spillner, G, Lutz, Hj, Böckler, D, Maeder, N, Busse, O, Grönniger, J, Haukamp, F, Balzer, K, Knoob, Hg, Roedig, G, Virreira, L, Franke, S, Moll, R, Schneider, J, Dayantas, J, Sechas, Mn, Tsiaza, S, Kiskinis, D, Apor, A, Dzinich, C, Entz, L, Hüttl, K, Jàrànyi, Z, Mogan, I, Nagy, Z, Szabo, A, Varga, D, Juhász, G, Mátyás, L, Hutchinson, M, Mehigan, D, Aladjem, Z, Harah, E, Elmakias, S, Gurvich, D, Yoffe, B, Ben Meir, H, Dagan, L, Karmeli, R, Keren, G, Shimony, A, Weller, B, Avrahami, R, Koren, R, Streifler, Jy, Tabachnik, S, Zelikovski, A, Angiletta, D, Federico, F, Impedovo, G, Marotta, V, Pascazio, L, Regina, G, Andreoli, A, Pozzati, E, Bonardelli, S, Giulini, Sm, Guarneri, B, Caiazzo, P, Mascoli, F, Becchi, G, Masini, R, Santoro, E, Simoni, G, Ventura, M, Scarpelli, P, Spartera, C, Arena, O, Collice, M, Puttini, M, Romani, F, Santilli, I, Segramora, V, Sterzi, R, Deriu, G, Verlato, F, Cao, Pg, Cieri, Enrico, De Rango, P, Moggi, L, Ricci, S, Antico, A, Spigonardo, F, Malferrari, G, Tusini, N, Vecchiati, E, Cavallaro, A, Kasemi, H, Marino, M, Sbarigia, E, Speziale, F, Zinicola, N, Alò, Fp, Bartolini, M, Carbonari, L, Caporelli, S, Grili Cicilioni, C, Lagalla, G, Ioannidis, G, Pagliariccio, G, Silvestrini, M, Palombo, D, Peinetti, F, Adovasio, R, Chiodo Grandi, F, Mase, G, Zamolo, F, Fregonese, V, Gonano, N, Mozzon, L, Blair, R, Chuen, J, Ferrar, D, Garbowski, M, Hamilton, Mj, Holdaway, C, Muthu, S, Shakibaie, F, Vasudevan, Tm, Kroese, A, Slagsvold, Ce, Dahl, T, Johnsen, Hj, Lange, C, Myhre, Ho, Gniadek, J, Andziak, P, Elwertowski, M, Leszczynski, J, Malek, Ak, Mieszkowski, J, Noszczyk, W, Szostek, M, Toutounchi, S, Correia, C, Pereira, Mc, Akchurin, Rs, Flis, V, Miksic, K, Stirn, B, Tetickovic, E, Cairols, M, Capdevila, Jm, Iborra Ortega, E, Obach, V, Riambau, V, Vidal Barraquer, F, Vila Coll, R, Diaz Vidal, E, Iglesias Negreia JI, Tovar Pardo, A, Iglesias, Rj, Alfageme, Af, Barba Velez, A, Estallo Laliena, L, Garcia Monco JC, Gonzalez, Lr, Corominas, C, Julia, J, Lozano, P, Marti Masso JF, Porta, Rm, Carrera, Ar, Gomez, J, Blomstrand, C, Gelin, J, Holm, J, Karlström, L, Mattsson, E, Bornhov, S, Dahlstrom, J, De Pedis, G, Jensen, Sm, Pärsson, H, Plate, G, Qvarfordt, P, Arvidsson, B, Brattström, L, Forssell, C, Potemkowski, A, Skiöldebrand, C, Stoor, P, Blomqvist, M, Calander, M, Lundgren, F, Almqvist, H, Norgren, L, Norrving, B, Ribbe, E, Thörne, J, Gottsäter, A, Mätzsch, T, Nilsson, Me, Lonsson, M, Stahre, B, Stenberg, B, Konrad, P, Jarl, L, Lundqvist, L, Olofsson, P, Rosfors, S, Swedenborg, J, Takolander, R, Bergqvist, D, Ljungman, C, Kniemeyer, Hw, Widmer, Mk, Kuster, R, Kaiser, R, Nagel, W, Sege, D, Weder, B, De Nie, J, Doelman, J, Yilmaz, N, Buth, J, Stultiens, G, Boiten, J, Boon, A, van der Linden, F, Busman, Dc, Sinnige, Ha, Yo, Ti, de Borst GJ, Eikelboom, Bc, Kappelle, Lj, Moll, F, Dortland, Rw, Westra, Te, Jaber, H, Manaa, J, Meftah, Rb, Nabil, Br, Sraieb, T, Bateman, D, Budd, J, Horrocks, M, Kivela, M, Shaw, L, Walker, R, D'Sa, Aa, 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Roberto, and Asymptomatic Carotid Surgery Trial Collaborative, Group
- Subjects
Male ,Time Factors ,medicine.medical_treatment ,Kaplan-Meier Estimate ,Carotid endarterectomy ,Aged ,80 and over ,Carotid Stenosis ,Endarterectomy ,Carotid ,Female ,Humans ,Incidence ,Middle Aged ,Primary Prevention ,Stroke ,Treatment Outcome ,Stroke/epidemiology ,law.invention ,Randomized controlled trial ,law ,Aged, 80 and over ,Endarterectomy, Carotid ,endarterectomy ,Carotid Stenosis/mortality ,Incidence (epidemiology) ,Carotid*/mortality ,General Medicine ,Carotid Stenosis | Internal Carotid Artery | Endarterectomy ,medicine.symptom ,medicine.medical_specialty ,Asymptomatic ,Internal medicine ,asymptomatic carotid artery stenosi ,medicine ,asymptomatic carotid artery stenosis ,business.industry ,Carotid Stenosis/complications ,Stroke/prevention & control ,Perioperative ,medicine.disease ,Surgery ,Stenosis ,Human medicine ,business - Abstract
SummaryBackgroundIf carotid artery narrowing remains asymptomatic (ie, has caused no recent stroke or other neurological symptoms), successful carotid endarterectomy (CEA) reduces stroke incidence for some years. We assessed the long-term effects of successful CEA.MethodsBetween 1993 and 2003, 3120 asymptomatic patients from 126 centres in 30 countries were allocated equally, by blinded minimised randomisation, to immediate CEA (median delay 1 month, IQR 0·3–2·5) or to indefinite deferral of any carotid procedure, and were followed up until death or for a median among survivors of 9 years (IQR 6–11). The primary outcomes were perioperative mortality and morbidity (death or stroke within 30 days) and non-perioperative stroke. Kaplan-Meier percentages and logrank p values are from intention-to-treat analyses. This study is registered, number ISRCTN26156392.Findings1560 patients were allocated immediate CEA versus 1560 allocated deferral of any carotid procedure. The proportions operated on while still asymptomatic were 89·7% versus 4·8% at 1 year (and 92·1% vs 16·5% at 5 years). Perioperative risk of stroke or death within 30 days was 3·0% (95% CI 2·4–3·9; 26 non-disabling strokes plus 34 disabling or fatal perioperative events in 1979 CEAs). Excluding perioperative events and non-stroke mortality, stroke risks (immediate vs deferred CEA) were 4·1% versus 10·0% at 5 years (gain 5·9%, 95% CI 4·0–7·8) and 10·8% versus 16·9% at 10 years (gain 6·1%, 2·7–9·4); ratio of stroke incidence rates 0·54, 95% CI 0·43–0·68, p
- Published
- 2010
50. Phenotypic and mtDNA variation in PhilippineKappaphycus cottonii(Gigartinales, Rhodophyta)
- Author
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Dumilag, Richard V., primary, Gallardo, William George M., additional, Garcia, Christian Philip C., additional, You, YeaEun, additional, Chaves, Alyssa Keren G., additional, and Agahan, Lance, additional
- Published
- 2017
- Full Text
- View/download PDF
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