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A 68-year-old man was followed up with chronic kidney disease. Follow-up CT incidentally detected a tumor at the left kidney and multiple small nodular shadows in the lungs bilaterally. The patient underwent needle biopsy and was diagnosed with Xp11.2 translocation renal cell carcinoma (RCC) pathologically. Hence, laparoscopic nephrectomy was performed. Fluorescence in situ hybridization analysis revealed a break-apart of the transcription factor E3 (TFE3) genes in the left tumor. After 2 months postoperatively, nivolumab and ipilimumab were administered thrice intravenously, considering the intermediate risk by the IMDC risk classification. However, pleural effusion occurred but was removed adequately. Lung metastasis decreased, but new metastasis occurred at the left iliopsoas muscle. Target therapy was performed with axitinib. Unfortunately, he died 6 months later postoperatively. These tumors commonly occur in children than in adults, and very rare in elderly patients. Xp11.2 translocation RCC in the elderly has a poorer prognosis than that in children. To date, no effective treatment for Xp11.2 translocation RCC has been established.

原発性直腸癌様所見を呈した胃癌術後直腸転移の1例を経験したので報告する.症例は58歳,女性. 1999年5月,胃癌の診断にて胃全摘術を施行した.病理組織学的所見はpor, se, INFγ, ly1, v0, n2 (+), stage IIIB,根治度Bであった.術後外来にてfollow中, 2001年12月,便秘症状がしだいにひどくなったため精査を施行した.注腸造影では直腸Raに比較的境界明瞭な約5cm大の全周性の狭窄を,また腹部CTでは直腸に全周性の壁肥厚を認め,直腸癌の診断にて低位前方切除術を施行した.病理組織学的には,胃癌と同等な低分化型腺癌が粘膜下層を中心に増殖しており,胃癌の直腸転移と診断した.胃癌の大腸転移は稀な疾患であり切除可能な症例は極めて少ない.中には原発性大腸癌との鑑別が困難な症例も散見される.注腸X線検査の詳細な検討による診断と治療方針の決定が必要とされる.