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1. End-of-life healthcare utilization in older patients with cancer: a large Belgian data linkage study

Author

Depoorter, V., primary, Vanschoenbeek, K., additional, Decoster, L., additional, Silversmit, G., additional, Debruyne, P., additional, De Groof, I., additional, Bron, D., additional, Cornélis, F., additional, Luce, S., additional, Focan, C., additional, Verschaeve, V., additional, Debugne, G., additional, Langenaeken, C., additional, Van Den Bulck, H., additional, Goeminne, J.C., additional, Teurfs, W., additional, Jerusalem, G., additional, Schrijvers, D., additional, Petit, B., additional, Rasschaert, M., additional, Praet, J.P., additional, Vandenborre, K., additional, De Schutter, H., additional, Milisen, K., additional, Flamaing, J., additional, Kenis, C., additional, Verdoodt, F., additional, and Wildiers, H., additional

Published
2023
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2. ICT-based oncogeriatric evaluation for management of older multimorbid patients: GerOnTe protocol

Author

Degol, L., primary, Hamaker, M., additional, Wildiers, H., additional, Ardito, V., additional, Barthod-Malat, A., additional, Davis, P., additional, Ferrara, L., additional, Kenis, C., additional, Kret, M., additional, Lalet, C., additional, Lehn, E., additional, Mathoulin-Pellissier, S., additional, O’hanlon, S., additional, O’sullivan, B., additional, Saillour-Glenisson, F., additional, Schwimmer, C., additional, Rostoft, S., additional, Staines, A., additional, Thevenet, V., additional, Vodjogbe, K., additional, Wallet, C., additional, and Soubeyran, P., additional

Published
2023
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4. Palliative care at the end-of-life in older patients with cancer and associated age-related factors

Author

Depoorter, V., primary, Vanschoenbeek, K., additional, Decoster, L., additional, Silversmit, G., additional, Debruyne, P., additional, De Groof, I., additional, Bron, D., additional, Cornélis, F., additional, Luce, S., additional, Focan, C., additional, Verschaeve, V., additional, Debugne, G., additional, Langenaeken, C., additional, Van Den Bulck, H., additional, Goeminne, J.C., additional, Teurfs, W., additional, Jerusalem, G., additional, Schrijvers, D., additional, Petit, B., additional, Rasschaert, M., additional, Praet, J.P., additional, Vandenborre, K., additional, De Schutter, H., additional, Milisen, K., additional, Flamaing, J., additional, Kenis, C., additional, Verdoodt, F., additional, and Wildiers, H., additional

Published
2023
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5. Determining clinically important differences in health-related quality of life in older patients with cancer undergoing chemotherapy or surgery

Author

Quinten, C., Kenis, C., Decoster, L., Debruyne, P. R., De Groof, I., Focan, C., Cornelis, F., Verschaeve, V., Bachmann, C., Bron, D., Luce, S., Debugne, G., Van den Bulck, H., Goeminne, J. C., Baitar, A., Geboers, K., Petit, B., Langenaeken, C., Van Rijswijk, R., Specenier, P., Jerusalem, G., Praet, J. P., Vandenborre, K., Lycke, M., Flamaing, J., Milisen, K., Lobelle, J. P., and Wildiers, H.

Published
2019

7. P004 - Essais randomisés en stepped-wedge - Leçons et défis de mise en œuvre avec l'exemple du projet GERONTE

Author

Thevenet, V., primary, Kret, M., additional, Arsandaux, J., additional, Ardito, V., additional, Degol, L., additional, Ferrara, L., additional, Hamaker, M., additional, Kenis, C., additional, Lehn, E., additional, Mathoulin-Pelissier, S., additional, Schwimmer, C., additional, Staines, A., additional, Vodjogbe, K., additional, Wallet, C., additional, Wildiers, H., additional, Soubeyran, P., additional, and Saillour-Glénisson, F., additional

Published
2023
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8. Geriatric Assessment and Functional Decline in Older Patients with Lung Cancer

Author

Decoster, L., Kenis, C., Schallier, D., Vansteenkiste, J., Nackaerts, K., Vanacker, L., and Vandewalle, N.

Subjects
Elderly patients -- Health aspects, Lung cancer -- Prognosis -- Research, Geriatric assessment -- Analysis, Health
Abstract

Purpose Older patients with lung cancer are a heterogeneous population making treatment decisions complex. This study aims to evaluate the value of geriatric assessment (GA) as well as the evolution of functional status (FS) in older patients with lung cancer, and to identify predictors associated with functional decline and overall survival (OS). Methods At baseline, GA was performed in patients [greater than or equal to]70 years with newly diagnosed lung cancer. FS measured by activities of daily living (ADL) and instrumental activities of daily living (IADL) was reassessed at follow-up to define functional decline and OS was collected. Predictors for functional decline and OS were determined. Results Two hundred and forty-five patients were included in this study. At baseline, GA deficiencies were present in all domains and ADL and IADL were impaired in 51 and 63% of patients, respectively. At follow-up, functional decline in ADL was observed in 23% and in IADL in 45% of patients. In multivariable analysis, radiotherapy was predictive for ADL decline. No other predictors for ADL or IADL decline were identified. Stage and baseline performance status were predictive for OS. Conclusions Older patients with lung cancer present with multiple deficiencies covering all geriatric domains. During treatment, functional decline is observed in almost half of the patients. None of the specific domains of the GA were predictive for functional decline or survival, probably because of the high impact of the aggressiveness of this tumor type leading to a poor prognosis., Author(s): L. Decoster [sup.1] , C. Kenis [sup.2] [sup.3] , D. Schallier [sup.1] , J. Vansteenkiste [sup.4] , K. Nackaerts [sup.4] , L. Vanacker [sup.1] , N. Vandewalle [sup.5] , [...]

Published
2017
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11. Hospitalizations, emergency department visits and home care in older patients after cancer diagnosis: results from a large data linkage study with 3 year follow-up

Author

Depoorter, V., primary, Vanschoenbeek, K., additional, Decoster, L., additional, De Schutter, H., additional, Debruyne, P.R., additional, De Groof, I., additional, Bron, D., additional, Cornélis, F., additional, Luce, S., additional, Focan, C., additional, Verschaeve, V., additional, Debugne, G., additional, Langenaeken, C., additional, Van Den Bulck, H., additional, Goeminne, J.C., additional, Teurfs, W., additional, Jerusalem, G., additional, Schrijvers, D., additional, Petit, B., additional, Rasschaert, M., additional, Praet, J.P., additional, Vandenborre, K., additional, Milisen, K., additional, Flamaing, J., additional, Kenis, C., additional, Verdoodt, F., additional, and Wildiers, H., additional

Published
2022
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12. Loneliness in older adults with cancer: A scoping review

Author

Pilleron, S., primary, Sun, V., additional, Hannan, M., additional, Haase, K., additional, Kenis, C., additional, Arthur, E.K., additional, Krok-Schoen, J., additional, Monginot, S., additional, Navarrete, E., additional, Nikita, N., additional, Roggendorf, S., additional, Schmidt, H., additional, Trevino, K., additional, Ayala, A.P., additional, and Puts, M., additional

Published
2022
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13. 1265MO Cause and place of death in older patients with cancer: Results from a large cohort study using linked clinical and population-based data

Author

Depoorter, V., primary, Vanschoenbeek, K., additional, Decoster, L., additional, De Schutter, H., additional, Debruyne, P.R., additional, De Groof, I., additional, Bron, D., additional, Cornelis, F., additional, Luce, S., additional, Focan, C., additional, Verschaeve, V., additional, Debugne, G., additional, Langenaeken, C.M., additional, van den Bulck, H.F.M., additional, Goeminne, J-C., additional, Milisen, K., additional, Flamaing, J., additional, Kenis, C., additional, Verdoodt, F., additional, and Wildiers, H., additional

Published
2022
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14. A Belgian survey on geriatric assessment in oncology focusing on large-scale implementation and related barriers and facilitators

Author

Kenis, C., Heeren, P., Decoster, L., Van Puyvelde, K., Conings, G., Cornelis, F., Cornette, P., Moor, R., Luce, S., Libert, Y., Van Rijswijk, R., Jerusalem, G., Rasschaert, M., Langenaeken, C., Baitar, A., Specenier, P., Geboers, K., Vandenborre, K., Debruyne, P.R., Vanoverbeke, K., Van Den Bulck, H., Praet, J.-P., Focan, C., Verschaeve, V., Nols, N., Goeminne, J.-C., Petit, B., Lobelle, J.-P., Flamaing, J., Milisen, K., and Wildiers, Hans

Published
2016
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16. International efforts in geriatric radiation oncology

Author

Naseer, A, Cree, A, Simcock, R, Jeppesen, SS, Morris, L, Kenis, C, Hashmi, A, Dale, W, O'Donovan, A, Naseer, A, Cree, A, Simcock, R, Jeppesen, SS, Morris, L, Kenis, C, Hashmi, A, Dale, W, and O'Donovan, A

Abstract

Introduction Geriatric assessment GA has been recommended to form part of treatment decision making for older adults with cancer However despite consensus guidelines from various organizations GA does not appear to be a part of routine practice in radiation oncology The aim of the current study was to explore the implementation of GA in radiation oncology Materials and Methods This anonymous international survey investigated current use of GA in patients presenting for radiation therapy aged 65 years and over in accordance with Checklist for Reporting Results of Internet E Surveys CHERRIES guidelines The survey was designed using Qualitrics an online survey tool It was distributed via SIOG social media and radiation oncology professional organizations Survey responses were analyzed using simple descriptive statistics An additional analysis by creating a dichotomous variable based on awareness of major clinical practice guidelines and current use of GA Results Among 158 respondents there was relatively low awareness of GA guidelines and low uptake of validated tools and processes A minority of participants only 16 stated that they had a specialized geriatric oncology program in their institution Approximately a third 34 of respondents were unaware of any GA clinical practice guidelines With regard to what way participants assess older patients differently to younger patients 16 reported formally using specific validated tools whereas 73 reported an informal assessment based on their own judgment with 5 reporting no difference between younger and older patients Regarding the use of validated screening tools for geriatric impairments over half reported using none 57 Regarding GA implementation the main barriers highlighted included a lack of clinical support staff a lack of training knowledge understanding or experience about GA and a lack of time Discussion Relatively low awareness of guidelines and low uptake of formal GA tools and processes were found The integratio

Published
2022

18. Ageism in cancer care: A scoping review by the International Society of Geriatric Oncology (SIOG) Nursing and Allied Health Interest Group

Author

Haase, K., primary, Sattar, S., additional, Pilleron, S., additional, Lambrechts, Y., additional, Hannan, M., additional, Navarrete, E., additional, Kantilal, K., additional, Newton, L., additional, Jin, R., additional, van der Wal-Huisman, H., additional, Strohschein, F., additional, Pergolotti, M., additional, Read, K., additional, Kenis, C., additional, and Puts, M., additional

Published
2021
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19. Geriatric screening and assessment among older patients with cancer: evaluation of long-term outcomes in a multicentric cohort of > 7, 000 patients

Author

Depoorter, V., primary, Vanschoenbeek, K., additional, Decoster, L., additional, De Schutter, H., additional, Debruyne, P.R., additional, De Groof, I., additional, Bron, D., additional, Cornélis, F., additional, Luce, S., additional, Focan, C., additional, Verschaeve, V., additional, Debugne, G., additional, Langenaeken, C., additional, Van Den Bulck, H., additional, Goeminne, J.C., additional, Teurfs, W., additional, Jerusalem, G., additional, Schrijvers, D., additional, Petit, B., additional, Geboers, K., additional, Forceville, K., additional, Praet, J.P., additional, Vandenborre, K., additional, Milisen, K., additional, Flamaing, J., additional, Kenis, C., additional, Verdoodt, F., additional, and Wildiers, H., additional

Published
2021
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23. Priorities for the global advancement of care for older adults with cancer: an update of the International Society of Geriatric Oncology Priorities Initiative

Author

Extermann, M., Brain, E., Canin, B., Cherian, M.N., Cheung, K.L., Glas, N. de, Devi, B., Hamaker, M., Kanesvaran, R., Karnakis, T., Kenis, C., Musolino, N., O'Donovan, A., Soto-Perez-de-Celis, E., Steer, C., Wildiers, H., and Int Soc Geriatric Oncology

Abstract

In 2011, the International Society of Geriatric Oncology (SIOG) published the SIOG 10 Priorities Initiative, which defined top priorities for the improvement of the care of older adults with cancer worldwide.' Substantial scientific, clinical, and educational progress has been made in line with these priorities and international health policy developments have occurred, such as the shift of emphasis by WHO from communicable to non-communicable diseases and the adoption by the UN of its Sustainable Development Goals 2030. Therefore, SIOG has updated its priority list. The present document addresses four priority domains: education, clinical practice, research, and strengthening collaborations and partnerships. In this Policy Review, we reflect on how these priorities would apply in different economic settings, namely in high-income countries versus low-income and middle-income countries. SIOG hopes that it will offer guidance for international and national endeavours to provide adequate universal health coverage for older adults with cancer, who represent a major and rapidly growing group in global epidemiology.

Published
2021

38. SIOG2022-0116 - Hospitalizations, emergency department visits and home care in older patients after cancer diagnosis: results from a large data linkage study with 3 year follow-up

Author

Depoorter, V., Vanschoenbeek, K., Decoster, L., De Schutter, H., Debruyne, P.R., De Groof, I., Bron, D., Cornélis, F., Luce, S., Focan, C., Verschaeve, V., Debugne, G., Langenaeken, C., Van Den Bulck, H., Goeminne, J.C., Teurfs, W., Jerusalem, G., Schrijvers, D., Petit, B., Rasschaert, M., Praet, J.P., Vandenborre, K., Milisen, K., Flamaing, J., Kenis, C., Verdoodt, F., and Wildiers, H.

Published
2022
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41. RIBOB: A study on the efficacy and safety of ribociclib in combination with letrozole in older women (≥70 years) with hormone receptor-positive (HR+) HER2-negative (HER2-) advanced breast cancer (aBC) with no prior systemic therapy for advanced disease

Author

Kenis, C., primary, Ponde, N.F., additional, Decoster, L., additional, de Azambuja, E., additional, Jerusalem, G., additional, Neven, P., additional, Dal Lago, L., additional, Denys, H., additional, Vuylsteke, P., additional, Duhoux, F.P., additional, and Wildiers, H., additional

Published
2019
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42. PS1517 MILD COGNITIVE IMPAIRMENT, HYPOALBUMINEMIA, HIGH CRP AND GASTRO-INTESTINAL ULCER: 4 MARKERS OF FRAILTY WHICH IDENTIFY OLDER PATIENTS WITH MALIGNANT HEMOPATHIES WHO DON’T BENEFIT FROM CHEMOTHERAPY

Author

Thibaud, V., primary, Deneve, L., additional, Dubruille, S., additional, Kenis, C., additional, Delforge, M., additional, Dal Lago, L., additional, Borghgraef, C., additional, Wildiers, H., additional, Pepersack, T., additional, de la Chapelle, T. Lamy, additional, and Bron, D., additional

Published
2019
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44. Determining clinically important differences in health-related quality of life in older patients with cancer undergoing chemotherapy or surgery

Author

Quinten, C., primary, Kenis, C., additional, Decoster, L., additional, Debruyne, P. R., additional, De Groof, I., additional, Focan, C., additional, Cornelis, F., additional, Verschaeve, V., additional, Bachmann, C., additional, Bron, D., additional, Luce, S., additional, Debugne, G., additional, Van den Bulck, H., additional, Goeminne, J. C., additional, Baitar, A., additional, Geboers, K., additional, Petit, B., additional, Langenaeken, C., additional, Van Rijswijk, R., additional, Specenier, P., additional, Jerusalem, G., additional, Praet, J. P., additional, Vandenborre, K., additional, Lycke, M., additional, Flamaing, J., additional, Milisen, K., additional, Lobelle, J. P., additional, and Wildiers, H., additional

Published
2018
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45. Multidisciplinary development of the Geriatric Core Dataset for clinical research in older patients with cancer: A French initiative with international survey

Author

Paillaud, E., primary, Soubeyran, P., additional, Caillet, P., additional, Cudennec, T., additional, Brain, E., additional, Terret, C., additional, Etchepare, F., additional, Mourey, L., additional, Aparicio, T., additional, Pamoukdjian, F., additional, Audisio, R.A., additional, Rostoft, S., additional, Hurria, A., additional, Bellera, C., additional, Mathoulin-Pélissier, S., additional, Boulahssass, R., additional, De Decker, L., additional, Fossey-Diaz, V., additional, Liuu, E., additional, Mertens, C., additional, Balardy, L., additional, Retornaz, F., additional, Couderc, A.L., additional, Rollot-Trad, F., additional, Azria, D., additional, Bacciarello, G., additional, Barranger, E., additional, Bengrine, L., additional, Bernat-Piazza, L., additional, Blay, J.Y., additional, Bourdolle, E., additional, Carola, E., additional, Chinot, O., additional, Classe, J.M., additional, Corre, R., additional, Culine, S., additional, Cure, H., additional, Delaloge S, S., additional, Delattre, J.Y., additional, Desolneux, G., additional, Freyer, G., additional, Graff, P., additional, Guigay, J., additional, Herlin, C., additional, Hoang-Xuan, K., additional, Italiano, A., additional, Kurtz, J.E., additional, Lartigau, E., additional, Lazarovicci-Nagera, C., additional, Lebas, I., additional, Le Caer, H., additional, Maguire, C., additional, Mir, O., additional, Natur, S., additional, Ortholan, C., additional, Pigneux, A., additional, Prou, M., additional, Qabbal, R., additional, Rousseau, F., additional, Rouzier, R., additional, Roveri, A., additional, Sargos, P., additional, Servagi, S., additional, Servent, V., additional, Ysebaert, L., additional, Alibhai, S., additional, Balducci, L., additional, Bastiaannet, E., additional, Bron, D., additional, Cheng, K., additional, Cohen, H.J., additional, Cornelis, F., additional, De Glas, N., additional, Kalsi, T., additional, Kanesvaran, R., additional, Kenis, C., additional, Hamaker, M., additional, Holmes, H., additional, Hsu, T., additional, Lichtman, S., additional, Mohile, S., additional, O'Donovan, A., additional, Puts, M., additional, Repetto, L., additional, Singhal, N., additional, Steer, C., additional, Stolz Baskett, P., additional, Van De Water, W., additional, Van Leuven, B., additional, Wedding, U., additional, Wildes, T., additional, Wildiers, H., additional, and Zulian, G., additional

Published
2018
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46. SIOG2021-0161 - Geriatric screening and assessment among older patients with cancer: evaluation of long-term outcomes in a multicentric cohort of > 7, 000 patients

Author

Depoorter, V., Vanschoenbeek, K., Decoster, L., De Schutter, H., Debruyne, P.R., De Groof, I., Bron, D., Cornélis, F., Luce, S., Focan, C., Verschaeve, V., Debugne, G., Langenaeken, C., Van Den Bulck, H., Goeminne, J.C., Teurfs, W., Jerusalem, G., Schrijvers, D., Petit, B., Geboers, K., Forceville, K., Praet, J.P., Vandenborre, K., Milisen, K., Flamaing, J., Kenis, C., Verdoodt, F., and Wildiers, H.

Published
2021
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48. Adherence to geriatric assessment-based recommendations in older patients with cancer: a multicenter prospective cohort study in Belgium.

Author

UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service d'oncologie médicale, Kenis, C, Decoster, L, Flamaing, J, Debruyne, P R, De Groof, I, Focan, C, Cornelis, F, Verschaeve, V, Bachmann, C, Bron, D, Luce, S, Debugne, G, Van den Bulck, H, Goeminne, Jean-Charles, Schrijvers, D, Geboers, K, Petit, B, Langenaeken, C, Van Rijswijk, R, Specenier, P, Jerusalem, G, Praet, J-P, Vandenborre, K, Lobelle, J-P, Lycke, M, Milisen, K, Wildiers, H, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service d'oncologie médicale, Kenis, C, Decoster, L, Flamaing, J, Debruyne, P R, De Groof, I, Focan, C, Cornelis, F, Verschaeve, V, Bachmann, C, Bron, D, Luce, S, Debugne, G, Van den Bulck, H, Goeminne, Jean-Charles, Schrijvers, D, Geboers, K, Petit, B, Langenaeken, C, Van Rijswijk, R, Specenier, P, Jerusalem, G, Praet, J-P, Vandenborre, K, Lobelle, J-P, Lycke, M, Milisen, K, and Wildiers, H

Abstract

In the general older population, geriatric assessment (GA)-guided treatment plans can improve overall survival, quality of life and functional status (FS). In GA-related research in geriatric oncology, studies mainly focused on geriatric screening and GA but not on geriatric recommendations, interventions and follow-up. The aim of this study was to investigate the adherence to geriatric recommendations and subsequent actions undertaken in older patients with cancer. A prospective Belgian multicenter (N=22) cohort study included patients ≥70 years with a malignant tumor upon oncologic treatment decision. Patients with an abnormal result on the geriatric screening (G8 ≤14/17) underwent GA. Geriatric recommendations were formulated based on GA results. At follow-up the adherence to geriatric recommendations was documented including a description of actions undertaken. From 11-2012 till 2-2015, G8 screening was performed in 8451 patients, of which 5838 patients had an abnormal result. Geriatric recommendations data were available for 5631 patients. Geriatric recommendations were made for 4459 patients. Geriatric interventions data were available for 4167 patients. A total of 12384 geriatric recommendations were made. At least one different geriatric recommendation was implemented in 2874 patients. A dietician, social worker and geriatrician intervened most frequently for problems detected on the nutritional, social and functional domain. A total of 7569 actions were undertaken for a total of 5725 geriatric interventions, most frequently nutritional support and supplements, extended home care and psychological support. This large scale Belgian study focuses on the adherence to geriatric recommendations and subsequent actions undertaken and contributes to the optimal management of older patients with cancer. We identified the domains for which geriatric recommendations are most frequently made and adhered to, and which referrals to other health care workers and facilities

Published
2018

49. Determining clinically important differences in health-related quality of life in older patients with cancer undergoing chemotherapy or surgery.

Author

UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service d'oncologie médicale, Quinten, C, Kenis, C, Decoster, L, Debruyne, P R, De Groof, I, Focan, C, Cornelis, F, Verschaeve, V, Bachmann, C, Bron, D, Luce, S, Debugne, G, Van den Bulck, H, Goeminne, Jean-Charles, Baitar, A, Geboers, K, Petit, B, Langenaeken, C, Van Rijswijk, R, Specenier, P, Jerusalem, G, Praet, J P, Vandenborre, K, Lycke, M, Flamaing, J, Milisen, K, Lobelle, J P, Wildiers, H, UCL - SSS/IREC/MONT - Pôle Mont Godinne, UCL - (MGD) Service d'oncologie médicale, Quinten, C, Kenis, C, Decoster, L, Debruyne, P R, De Groof, I, Focan, C, Cornelis, F, Verschaeve, V, Bachmann, C, Bron, D, Luce, S, Debugne, G, Van den Bulck, H, Goeminne, Jean-Charles, Baitar, A, Geboers, K, Petit, B, Langenaeken, C, Van Rijswijk, R, Specenier, P, Jerusalem, G, Praet, J P, Vandenborre, K, Lycke, M, Flamaing, J, Milisen, K, Lobelle, J P, and Wildiers, H

Abstract

Using the EORTC Global Health Status (GHS) scale, we aimed to determine minimal clinically important differences (MCID) in health-related quality of life (HRQOL) changes for older cancer patients with a geriatric risk profile, as defined by the geriatric 8 (G8) health screening tool, undergoing treatment. Simultaneously, we assessed baseline patient characteristics prognostic for HRQOL changes. Our analysis included 1424 (G8 ≤ 14) older patients with cancer scheduled to receive chemotherapy (n = 683) or surgery (n = 741). Anchor-based methods, linking the GHS score to clinical indicators, were used to determine MCID between baseline and follow-up at 3 months. A threshold of 0.2 standard deviation (SD) was used to exclude MCID estimates too small for interpretation. Logistic regressions analysed baseline patient characteristics prognostic for HRQOL changes. The 15-item Geriatric Depression Scale (GDS15), Visual Analogue Scale (VAS) for Fatigue and ECOG Performance Status (PS) were selected as clinical anchors. In the surgery group, MCID estimates for improvement and deterioration were ECOG PS (5*, 11*), GDS15 (5*, 2) and VAS Fatigue (3, 9*). In the chemotherapy group, MCID estimates for improvement and deterioration were ECOG PS (8*, 7*), GDS15 (5, 4) and VAS Fatigue (5, 5*). Estimates with * were > 0.2 SD threshold. Patients experiencing pain or malnutrition (surgery group) or fatigue (chemotherapy group) at baseline showed a significantly stable or improved HRQOL (p < 0.05) after their treatment. The reported MCID for improvement and deterioration depended on the anchor used and treatment received. The estimates can be used to evaluate significant changes in HRQOL and to determine sample sizes in clinical trials.

Published
2018

50. Cognitive Impairment, Hypoalbuminemia, High CRP Level and Past History of Gastro-Intestinal Ulcer: 4 Markers of Frailty Which Identify Older Patients with Malignant Hemopathies Who Shouldn't Benefit from Chemotherapy

Author

Dubruille, Stéphanie, Kenis, C, Thibaud, Vincent, Libert, Yves, Delforge, Michel, Dal Lago, Lissandra, Roos, Myriam, Borghgraef, Cindy, Pepersack, Thierry, Wildiers, Hans, Bron, Dominique, Dubruille, Stéphanie, Kenis, C, Thibaud, Vincent, Libert, Yves, Delforge, Michel, Dal Lago, Lissandra, Roos, Myriam, Borghgraef, Cindy, Pepersack, Thierry, Wildiers, Hans, and Bron, Dominique

Abstract

info:eu-repo/semantics/published

Published
2018

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