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9 results on '"Kemppainen, Kaisa M."'

2. Early Childhood Gut Microbiomes Show Strong Geographic Differences Among Subjects at High Risk for Type 1 Diabetes

Author

Kemppainen, Kaisa M., Ardissone, Alexandria N., Davis-Richardson, Austin G., Fagen, Jennie R., Gano, Kelsey A., León-Novelo, Luis G., Vehik, Kendra, Casella, George, Simell, Olli, Ziegler, Anette G., Rewers, Marian J., Lernmark, Åke, Hagopian, William, She, Jin-Xiong, Krischer, Jeffrey P., Akolkar, Beena, Schatz, Desmond A., Atkinson, Mark A., and Triplett, Eric W.

Published
2015
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4. TWO APPLICATIONS OF PERMUTATION TESTS IN BIOSTASTICS

Author

LEÓN-NOVELO, LUIS, KEMPPAINEN, KAISA M., ARDISSONE, ALEXANDRIA, DAVIS-RICHARDSON, AUSTIN, FAGEN, JENNIE, GANO, KELSEY, and TRIPLETT, ERIC W.

Subjects
Article
Abstract

We show two examples of how we answer biological questions by converting them into statistical hypothesis testing problems. We consider gene abundance data, and apply permutation tests. Though these tests are simple, they allow us to test biologically relevant hypotheses. Here we present the analysis of data rising from two studies on Type 1 Diabetes. In the first study [3] are interested in comparing the gut bacterial biodiversity in children at risk and not at risk of developing diabetes. In the second study, [4] compare the gut bacterial biodiversity of children in six different sites in USA and Europe. The statistical analyses presented here are parts of the "statistical methods" in two papers mentioned above. Here we offer a detailed explanation of the "Statistical Methods" addressed to readers with a statistics background.

Published
2013

5. Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity.

Author

Kemppainen, Kaisa M., Vehik, Kendra, Lynch, Kristian F., Larsson, Helena Elding, Canepa, Ronald J., Simell, Ville, Koletzko, Sibylle, Liu, Edwin, Simell, Olli G., Toppari, Jorma, Ziegler, Anette G., Rewers, Marian J., Lernmark, Åke, Hagopian, William A., Jin-Xiong She, Akolkar, Beena, Schatz, Desmond A., Atkinson, Mark A., Blaser, Martin J., and Krischer, Jeffrey P.

Published
2017
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6. The methylome of the gut microbiome

Author

University of Helsinki, Clinicum, Leonard, Michael T., Davis-Richardson, Austin G., Ardissone, Alexandria N., Kemppainen, Kaisa M., Drew, Jennifer C., Ilonen, Jorma, Knip, Mikael, Simell, Olli, Toppari, Jorma, Veijola, Riitta, Hyoty, Heikki, Triplett, Eric W., University of Helsinki, Clinicum, Leonard, Michael T., Davis-Richardson, Austin G., Ardissone, Alexandria N., Kemppainen, Kaisa M., Drew, Jennifer C., Ilonen, Jorma, Knip, Mikael, Simell, Olli, Toppari, Jorma, Veijola, Riitta, Hyoty, Heikki, and Triplett, Eric W.

Published
2014

7. Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes

Author

Davis-Richardson, Austin G., primary, Ardissone, Alexandria N., additional, Dias, Raquel, additional, Simell, Ville, additional, Leonard, Michael T., additional, Kemppainen, Kaisa M., additional, Drew, Jennifer C., additional, Schatz, Desmond, additional, Atkinson, Mark A., additional, Kolaczkowski, Bryan, additional, Ilonen, Jorma, additional, Knip, Mikael, additional, Toppari, Jorma, additional, Nurminen, Noora, additional, Hyöty, Heikki, additional, Veijola, Riitta, additional, Simell, Tuula, additional, Mykkänen, Juha, additional, Simell, Olli, additional, and Triplett, Eric W., additional

Published
2014
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8. The methylome of the gut microbiome: disparate Dam methylation patterns in intestinal Bacteroides dorei

Author

Leonard, Michael T., primary, Davis-Richardson, Austin G., additional, Ardissone, Alexandria N., additional, Kemppainen, Kaisa M., additional, Drew, Jennifer C., additional, Ilonen, Jorma, additional, Knip, Mikael, additional, Simell, Olli, additional, Toppari, Jorma, additional, Veijola, Riitta, additional, Hyöty, Heikki, additional, and Triplett, Eric W., additional

Published
2014
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9. TWO APPLICATIONS OF PERMUTATION TESTS IN BIOSTASTICS.

Author

León-Novelo L, Kemppainen KM, Ardissone A, Davis-Richardson A, Fagen J, Gano K, and Triplett EW

Abstract

We show two examples of how we answer biological questions by converting them into statistical hypothesis testing problems. We consider gene abundance data, and apply permutation tests. Though these tests are simple, they allow us to test biologically relevant hypotheses. Here we present the analysis of data rising from two studies on Type 1 Diabetes. In the first study [3] are interested in comparing the gut bacterial biodiversity in children at risk and not at risk of developing diabetes. In the second study, [4] compare the gut bacterial biodiversity of children in six different sites in USA and Europe. The statistical analyses presented here are parts of the "statistical methods" in two papers mentioned above. Here we offer a detailed explanation of the "Statistical Methods" addressed to readers with a statistics background.

Published
2013

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