243 results on '"Kempaiah, Prakasha"'
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2. Target-Based Rational Improvement Strategies and Pitfalls in Leishmania Drug Discovery
3. Versatile Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Antileishmanial Drugs
4. TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome
5. Growth inhibition of plasmodium falciparum by Nano-molar concentrations of 1-(4‑hydroxy-3-methoxyphenyl) decan-3-one (6-paradol); is a cure at hand?
6. Genetic variation in CSF2 (5q31.1) is associated with longitudinal susceptibility to pediatric malaria, severe malarial anemia, and all-cause mortality in a high-burden malaria and HIV region of Kenya
7. Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays
8. Multi-targeting approach for nsp3, nsp9, nsp12 and nsp15 proteins of SARS-CoV-2 by Diosmin as illustrated by molecular docking and molecular dynamics simulation methodologies
9. Mycobacterium lepromatosis MLPM_5000 is a potential heme chaperone protein HemW and mis-annotation of its orthologues in mycobacteria
10. Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach
11. Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy
12. A Review of the Preclinical and Clinical Efficacy of Remdesivir, Hydroxychloroquine, and Lopinavir-Ritonavir Treatments against COVID-19
13. Oseltamivir analogs with potent anti-influenza virus activity
14. Decoding Immuno-Competence: A Novel Analysis of Complete Blood Cell Count Data in COVID-19 Outcomes
15. Antiplasmodial activity of hydroxyethylamine analogs: Synthesis, biological activity and structure activity relationship of plasmepsin inhibitors
16. Author Correction: Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model
17. Data structuring may prevent ambiguity and improve personalized medical prognosis
18. Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
19. Genetic variation in interleukin-7 is associated with a reduced erythropoietic response in Kenyan children infected with Plasmodium falciparum
20. An electrochemiluminescence based assay for quantitative detection of endogenous and exogenously applied MeCP2 protein variants
21. Mycolactone: A Broad Spectrum Multitarget Antiviral Active in the Picomolar Range for COVID-19 Prevention and Cure
22. Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry
23. In Silico Binding of 2-Aminocyclobutanones to SARS-CoV-2 Nsp13 Helicase and Demonstration of Antiviral Activity
24. Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon
25. The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis
26. Structure-Based Identification of Natural-Product-Derived Compounds with Potential to Inhibit HIV-1 Entry
27. Cystic fibrosis CFBE41o‐ cells contain TLR1 SNP I602S and fail to respond to Mycobacterium abscessus
28. Reduced Hsp70 and Glutamine in Pediatric Severe Malaria Anemia: Role of hemozoin in Suppressing Hsp70 and NF-κB Activation
29. Synergistic blending of high-valued heterocycles inhibits growth of Plasmodium falciparum in culture and P. berghei infection in mouse model
30. Repurposing Lansoprazole and Posaconazole to treat Leishmaniasis: Integration of in vitro testing, pharmacological corroboration, and mechanisms of action
31. Testing-Related and Geo-Demographic Indicators Strongly Predict COVID-19 Deaths in the United States during March of 2020
32. Multi-Cellular Immunological Interactions Associated With COVID-19 Infections
33. Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit
34. The Multistage Antimalarial Compound Calxinin Modulates Calcium Homeostasis Targeting a Unique Calcium Channel Involved in Subcellular Calcium Storage in P. falciparum
35. Human tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system
36. Reduced interferon (IFN)-α conditioned by IFNA2 (−173) and IFNA8 (−884) haplotypes is associated with enhanced susceptibility to severe malarial anemia and longitudinal all-cause mortality
37. Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children
38. Testing-Related and Geo-Demographic Indicators Strongly Predict COVID-19 Deaths in the United States during March of 2020
39. Revealing SARS-CoV-2 Functional Druggability Through Multi-Target Cadd Screening of Repurposable Drugs
40. The Global Burden of Severe Falciparum Malaria: An Immunological and Genetic Perspective on Pathogenesis
41. The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca 2+ Homeostasis by Targeting a Unique Ion Channel.
42. Reduced systemic bicyclo-prostaglandin-E2 and cyclooxygenase-2 gene expression are associated with inefficient erythropoiesis and enhanced uptake of monocytic hemozoin in children with severe malarial anemia
43. Comparative genomic and phenotypic characterization of invasive non-typhoidal Salmonella isolates from Siaya, Kenya
44. Personalized and dynamic antibiograms-an exploration in seven infectious syndromes
45. Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model
46. Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening and in vitro assays
47. Review of Atypical Organometallic Compounds as Antimalarial Drugs
48. Early and massive testing saves lives: COVID-19 related infections and deaths in the United States during March of 2020
49. Revealing SARS-CoV-2 Functional Druggability Through Multi-Target Cadd Screening of Repurposable Drugs
50. Bioactive Chemical Entities: Pre-clinical and Clinical Aspects - Part-II
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