8 results on '"Keith Klein"'
Search Results
2. First report of rapid eye color change in a non‐avian tetrapod
- Author
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Chaz Rhodes, Keith Klein, and Bradley E. Carlson
- Subjects
medicine.anatomical_structure ,law ,Evolutionary biology ,medicine ,Tetrapod (structure) ,Animal Science and Zoology ,Eye color change ,Turtle (robot) ,Iris (anatomy) ,Biology ,Ecology, Evolution, Behavior and Systematics ,law.invention - Published
- 2020
3. Diabetic ketoacidosis after the treatment of anaphylaxis
- Author
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Daniel S Brenner, Keith Kleinman, Amy Manzo, Melania M Bembea, and David W Cooke
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Diseases of the endocrine glands. Clinical endocrinology ,RC648-665 - Abstract
Anaphylaxis is a rapidly progressive potentially lethal condition, and epinephrine is the most crucial medication in its treatment. In this study, we present a case of diabetic ketoacidosis in a young woman that was precipitated by the administration of epinephrine to treat anaphylaxis. This patient had diabetes mellitus and poor glycemic control and developed ketoacidosis despite having evidence of ongoing endogenous insulin production and having been treated with exogenous long-acting insulin less than 24 h prior to the event. This is a rare, serious, adverse side effect of life-saving medication. This report demonstrates that the risk of diabetic ketoacidosis should be considered when administering epinephrine to patients with diabetes, even in the absence of complete insulin deficiency.
- Published
- 2022
- Full Text
- View/download PDF
4. A molecular toolbox for manipulating Eremothecium coryli
- Author
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Alexander Dünkler, Andrea Walther, Selina Gastmann, Keith Klein, and Jürgen Wendland
- Subjects
Microbiological Techniques ,Antifungal Agents ,Genetic Vectors ,Green Fluorescent Proteins ,Saccharomyces cerevisiae ,Microbiology ,chemistry.chemical_compound ,Transformation, Genetic ,Plasmid ,Eremothecium gossypii ,Drug Resistance, Fungal ,Genes, Reporter ,Promoter Regions, Genetic ,Molecular Biology ,Selectable marker ,Eremothecium coryli ,Genetics ,biology ,beta-Galactosidase ,biology.organism_classification ,Artificial Gene Fusion ,Eremothecium ,Transformation (genetics) ,chemistry ,Saccharomycetales ,Streptothricins ,Nourseothricin ,Gentamicins ,Dimorphic fungus ,Plasmids - Abstract
The genus Eremothecium contains dimorphic and filamentous fungal species, most notably Eremothecium sinecaudum (Holleya sinecauda), a dimorphic plant pathogen, which was isolated from mustard seeds, and Eremothecium gossypii (Ashbya gossypii), a filamentous fungus, which is well known for its ability to produce riboflavin. In this study, we present the initial molecular characterization of another Eremothecium species classified as Eremothecium coryli. E.coryli is a dimorphic fungus. We have developed, based on previously described reagents, a transformation system for E. coryli using kanMX and NATMX3 as dominant selectable marker genes on freely replicating plasmids conferring resistance to the antibiotics G418 and nourseothricin, respectively. As reporter genes we could introduce lacZ and GFP, which were controlled either by the AgTEF1 promoter or by regulatable MET promoters derived from the A. gossypii and Saccharomyces cerevisiae MET3 genes. These newly established tools will allow a detailed comparison of different growth modes in filamentous or dimorphic species within the genus Eremothecium.
- Published
- 2007
5. Building the university/public school partnership: A workshop for mentor teachers
- Author
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Karen D. Hager, Martha T. Dever, and Keith Klein
- Subjects
ComputingMilieux_THECOMPUTINGPROFESSION ,Higher education ,business.industry ,Evaluation data ,General partnership ,Pedagogy ,ComputingMilieux_COMPUTERSANDEDUCATION ,Student teacher ,business ,Psychology ,Teacher education ,Education - Abstract
Strong teacher education programs acknowledge the importance of a partnership between teacher education and public school faculties and the important role mentor teachers play in the education of student teachers. Studies suggest that mentor teachers trained in supervision are more effective than those who are not. This article describes the development, implementation, and evaluation of a workshop for mentor teachers that reflects the collaborative effort of university and public school faculties. The particular focus of this workshop was on giving feedback to student teachers. Evaluation data suggest that mentor teachers felt the workshop provided helpful information.
- Published
- 2003
6. Paediatric chest compression performance improves via novel augmented-reality cardiopulmonary resuscitation feedback system: A mixed-methods pilot study in a simulation-based setting
- Author
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Justin M. Jeffers, Blake A. Schreurs, James L. Dean, Brandon Scott, Therese Canares, Sean Tackett, Brittany Smith, Emma Billings, Veena Billioux, Harshini D. Sampathkumar, and Keith Kleinman
- Subjects
Paediatric CPR ,Augmented Reality ,Simulation ,Resuscitation ,CPR Feedback ,Mixed-methods ,Specialties of internal medicine ,RC581-951 - Abstract
Aim: More than 20,000 children experience a cardiac arrest event each year in the United States. Most children do not survive. High-quality cardiopulmonary resuscitation (CPR) has been associated with improved outcomes yet adherence to guidelines is poor. We developed and tested an augmented reality head mounted display chest compression (CC) feedback system (AR-CPR) designed to provide real-time CC feedback and guidance. Methods: We conducted an unblinded randomized crossover simulation-based study to determine whether AR-CPR changes a user's CC performance. A convenience sample of healthcare providers who perform CC on children were included. Subjects performed three two-minute cycles of CC during a simulated 18-minute paediatric cardiac arrest. Subjects were randomized to utilize AR-CPR in the second or third CC cycle. After, subjects participated in a qualitative portion to inquire about their experience with AR-CPR and offer criticisms and suggestions for future development. Results: There were 34 subjects recruited. Sixteen subjects were randomly assigned to have AR-CPR in cycle two (Group A) and 18 subjects were randomized to have AR-CPR in cycle three (Group B). There were no differences between groups CC performance in cycle one (baseline). In cycle two, subjects in Group A had 73% (SD 18%) perfect CC epochs compared to 17% (SD 26%) in Group B (p
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- 2022
- Full Text
- View/download PDF
7. Peacemaking in Civil War: International Mediation in Zimbabwe, 1974-1980 (review)
- Author
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Keith Klein
- Subjects
Spanish Civil War ,Law ,Political science ,Military operations other than war ,Mediation ,Peacemaking ,Asymmetric warfare ,General Medicine - Published
- 1991
8. Pediatric Coping During Venipuncture With Virtual Reality: Pilot Randomized Controlled Trial
- Author
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Therese Canares, Carisa Parrish, Christine Santos, Alia Badawi, Alyssa Stewart, Keith Kleinman, Kevin Psoter, and Joseph McGuire
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Pediatrics ,RJ1-570 - Abstract
BackgroundVirtual reality (VR) has shown promise in reducing children’s pain and anxiety during venipuncture, but studies on VR lack objective observations of pediatric coping. Notably, the process of capturing objective behavioral coping data can be labor- and personnel-intensive. ObjectiveThe primary aims of this pilot trial were to assess the feasibility of conducting a trial of VR in a pediatric emergency department and the feasibility of documenting observed coping behaviors during pediatric procedures. Secondarily, this study examined whether VR affects child and caregiver coping and distress during venipuncture in the pediatric emergency department. MethodsThis stratified, randomized, controlled pilot trial compared coping and distress between child life–supported VR engagement and child life specialist support without VR during painful procedures in children aged 7-22 years in the pediatric emergency department. An external control (reference group) received no standardized support. Primary feasibility outcomes included rates of recruitment, rates of withdrawal from VR, and rates of completed Child Adult Medical Procedure Interaction Scale-Short Form (CAMPIS-SF) observations. Secondary clinical outcomes were applied to venipuncture procedures and included CAMPIS-SF coping and distress (range 0-1.0), pain and anxiety on a visual analog scale (range 0-10), and cybersickness symptoms. ResultsOverall recruitment was 93% (66/71), VR withdrawal rate was 27% (4/15), and of the completed procedures, 100% (63/63) CAMPIS-SF observations were completed. A total of 55 patients undergoing venipuncture in the pediatric emergency department were included in the analyses of clinical outcomes: 15 patients (15 caregivers) randomized to VR, 20 patients (15 caregivers) randomized to child life specialist support, and 20 patients (17 caregivers) in the reference group. Patient coping differed across groups with higher coping in the VR group and child life specialist group than in the reference group (P=.046). There were no significant differences in the distress and pain ratings for patients and caregivers between the groups. Caregivers rated the lowest perceived anxiety in the child life specialist group (P=.03). There was no apparent change in cybersickness symptoms before and after VR use (P=.37). ConclusionsReal-time documentation of observed behaviors in patients and caregivers was feasible during medical procedures in which VR was utilized, particularly with the availability of research staff. VR and child life specialists improved coping in children during venipuncture procedures. Given the high participation rate, future studies to evaluate the efficacy of VR are recommended to determine whether an off-the-shelf VR headset can be a low-cost and low-risk tool to improve children’s coping during venipuncture or other related procedures. Trial RegistrationClinicalTrials.gov NCT03686176; https://clinicaltrials.gov/ct2/show/NCT03686176
- Published
- 2021
- Full Text
- View/download PDF
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