131 results on '"Keenan, Martine"'
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2. Short-course combination treatment for experimental chronic Chagas disease
3. DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc 1
4. A new approach to the synthesis of coelenterazine
5. DNDI-6174 is a preclinical candidate for visceral leishmaniasis that targets the cytochrome bc1.
6. Allosteric Potentiators of Neuronal Nicotinic Cholinergic Receptors: Potential Treatments for Neurodegenerative Disorders
7. Complexes of Trypanosoma cruzi Sterol 14α-Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease: STRUCTURAL BASIS FOR PATHOGEN SELECTIVITY
8. Design, structure–activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi
9. A New Era for Chagas Disease Drug Discovery?
10. Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi
11. Designing Drugs to Target Trypanosoma cruzi , the Etiological Agent of Chagas Disease: When Chemistry needs Biology
12. PSAB-OFP, a selective α7 nicotinic receptor agonist, is also a potent agonist of the 5-HT 3 receptor
13. Glowing jellyfish, luminescence and a molecule called coelenterazine
14. Enantioselective Heck reactions using chiral P,N-ligands
15. Chapter Four - A New Era for Chagas Disease Drug Discovery?
16. The tethered aminohydroxylation (TA) of cyclic allylic carbamates
17. Allosteric Potentiators of Neuronal Nicotinic Cholinergic Receptors: Potential Treatments for Neurodegenerative Disorders
18. Two Analogues of Fenarimol Show Curative Activity in an Experimental Model of Chagas Disease
19. Analogues of Fenarimol Are Potent Inhibitors of Trypanosoma cruzi and Are Efficacious in a Murine Model of Chagas Disease
20. Boron-based drugs as antiprotozoals
21. ChemInform Abstract: Enantioselective Heck Reactions Using Chiral P,N-Ligands
22. Contra-Friedel—Crafts tert-Butylation of Substituted Aromatic Rings via Directed Metalation and Sulfinylation.
23. New Facile and Mild Synthesis of 2-Substituted Oxazolopyridines.
24. Addition of Lithiated Tertiary Aromatic Amides to Epoxides and Aziridines: Asymmetric Synthesis of (S)-(+)-Mellein
25. High Affinity Ligands for the α7 Nicotinic Receptor that Show no Cross‐Reactivity with the 5‐HT3 Receptor.
26. Asymmetric Ortholithiation of Amides by Conformationally Mediated Chiral Memory: An Enantioselective Route to Naphtho- and Benzofuranones.
27. High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor
28. Concise and Enantioselective Synthesis of the Aminocyclitol Core of Hygromycin A
29. Efficient Acyclic Stereocontrol Using the Tethered Aminohydroxylation Reaction.
30. Synthesis of Versatile Chiral N,P Ligands Derived from Pyridine and Quinoline.
31. Synthesis of Versatile Chiral N,P Ligands Derived from Pyridine and Quinoline
32. Fast racemisation and slow epimerisation of laterally lithiated amides: stereochemical evidence for the mechanism of inversion of amide-substituted benzyllithiums
33. Bicyclo[2.2.1]heptanes as novel triple re-uptake inhibitors for the treatment of depression
34. Synthesis of Pyridine Fused Polycyclic Amines Using Sequential Ring-Closing Metathesis and Radical Cyclization Reactions.
35. Synthesis of pyridine fused polycyclic amines using sequential ring-closing metathesis and radical cyclisation reactions
36. The Tethered Aminohydroxylation (TA) of Cyclic Allylic Carbamates.
37. Allosteric Potentiators of Neuronal Nicotinic Cholinergic Receptors: Potential Treatments for Neurodegenerative Disorders.
38. PSAB-OFP, a selective α7 nicotinic receptor agonist, is also a potent agonist of the 5-HT3 receptor
39. The regioselective aminohydroxylation of allylic carbamates
40. High affinity ligands for the α7 nicotinic receptor that show no cross-reactivity with the 5-HT 3 receptor
41. New facile and mild synthesis of 2-substituted oxazolopyridines
42. Highly efficient and flexible total synthesis of coelenterazine
43. A Suzuki Coupling Approach to Pyrazines Related to Coelenterazine
44. Two Analogues of FenarimolShow Curative Activity in an Experimental Model of Chagas Disease.
45. Analogues of FenarimolAre Potent Inhibitors of Trypanosoma cruziand Are Efficacious in a Murine Model of Chagas Disease.
46. Asymmetric Ortholithiation of Amides by Conformationally Mediated Chiral Memory: An Enantioselective Route to Naphtho- and Benzofuranones.
47. Synthesis of Versatile Chiral N,P Ligands Derived from Pyridine and Quinoline
48. Contra-Friedel–Crafts tert-butylation of substituted aromatic rings viadirected metallation and sulfinylationElectronic supplementary information (ESI) available: Experimental procedures and characterisation data for all new compounds. See DOI: 10.1039/b600181e
49. The regioselective aminohydroxylation of allylic carbamates
50. High Affinity Ligands for the α7 Nicotinic Receptor that Show no Cross-Reactivity with the 5-HT3 Receptor.
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