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OBJECTIVE To collect voided urine from dogs with clinical signs of lower UTI and determine the diagnostic performance of a commercially available rapid immunoassay (RIA) immediately after urine collection and after refrigeration at 4 ariel 24 hours. ANIMALS 40 client-owned dogs. METHODS Aerobic urine culture was performed on urine collected by cystocentesis. Urine samples were collected by voiding, and the RIA performed in triplicate within 30 minutes (time 0) and again in triplicate after 4 and 24 hours of refrigeration. Test precision and agreement between culture results and RIA results at each time point were determined, and factors possibly associated with false results investigated. RESULTS 14 of 40 dogs (35%) had UTI verified by aerobic urine culture, and all had positive RIA. Three dogs had false positive RIA results. Sensitivity, specificity, positive predictive value, and negative predictive value of the RIA were 100, 88%, 82%, and 100%, respectively, and results were not different after 4 and 24 hours of refrigeration. Precision was excellent. CLINICAL RELEVANCE This point-of-care RIA, performed on voided urine refrigerated up to 24 hours, rapidly and accurately identifies bacteriuria in dogs with lower urinary tract clinical signs, inexpensively. [ABSTRACT FROM AUTHOR]

Objectives: Urinary tract infections (UTIs) are reported to be relatively common in hyperthyroid cats, with prevalence rates ranging from 12% to 22%. Factors that are associated with UTIs include age, decreasing body weight and active urine sediments. The purpose of this study was to investigate the prevalence of positive urine cultures (PUCs) in hyperthyroid cats and associated risk factors for PUC. Methods: In total, 197 hyperthyroid cats presenting for radioiodine therapy had urine cultures prospectively performed on cystocentesis samples. Data pertaining to clinical signs, drug history, age, weight, blood urea nitrogen, creatinine, serum thyroxine and urinalysis were also evaluated. Results: The prevalence of PUCs in this population of hyperthyroid cats was 5.1% and all cats were subclinical. Microscopic bacteriuria was significantly associated with a PUC (60%) compared with a negative urine culture (1.6%) status. Age, weight, urine specific gravity <1.020, urine pH, hematuria, pyuria, thyroxine concentration, breed and sex were not associated with PUC status. Conclusions and relevance: The prevalence of PUCs in this population of cats was lower than previous reports of cats with hyperthyroidism. Cats with a PUC were subclinical at the time of culture, regardless of urine sediment abnormalities. Further studies are necessary to determine the clinical significance of subclinical bacteriuria in hyperthyroid cats. [ABSTRACT FROM AUTHOR]

Objective--To characterize the gait of small-breed dogs walked on a pressure walkway by handlers moving at a metronome-set tempo and to determine the influence of handler and leash side on gait characteristics. Design--Prospective study. Animals--5 healthy adult small-breed dogs weighing < 11.4 kg (25 lb). Procedures--Dogs were walked by each of 5 handlers moving at a metronome-set tempo (100 beats/min). Velocity, cadence, stance time, number of activated sensors, total pressure index (TPI), left or right hind reach, and symmetry indices were obtained with the leash on the left and right sides of each dog for each handler. Results--Coefficients of variation for TPI and stance time approximated 30%, whereas coefficients of variation for symmetry indices remained < 20%. Changing handlers and leash side did not influence hind limb variables. Changing handlers influenced the TPI of the forelimbs, inducing changes of up to 8%. Leash side accounted for 12% and 14% of the variation in symmetry indices of TPI and number of sensors activated between forelimbs, respectively (mean alterations for recorded variables, 9%). Conclusions and Clinical Relevance--Symmetry indices appeared to vary less than variables obtained for individual dog limbs, and it may therefore be advantageous to determine those indices during large trials. Handlers or leash side may be changed in studies focusing on dogs' hind limbs without affecting results. Use of symmetry indices is recommended in forelimb studies requiring multiple handlers. Pressure walkway analyses of the forelimbs should include equal distribution of left- and right-sided leash-led trials, given that smallbreed dogs tended to shift weight toward the forelimb opposite the leash. [ABSTRACT FROM AUTHOR]