1. Herbal Transformation by Fermentation
- Author
-
Chang-Gue Son, Sam-Keun Lee, In-Kyu Choi, Eun-Su Jang, and Kee-Jung Bang
- Subjects
cynanchi atrati Radix ,fermentation ,herbal ,lactobacillus ,Other systems of medicine ,RZ201-999 - Abstract
We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completely changed into anti-melanin activity at very low concentration after Lactobacillus -fermentation. In addition, the compounds were drastically changed as shown in HPLC-based profile. Furthermore, this transformation has been achieved by only Lactobacillus -fermentation. This study proposes an strategy which we need to consider in the herb-derived material researches including pharmacopuncture.
- Published
- 2020
- Full Text
- View/download PDF