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To investigate mass transport and energy dissipation in space environments for solar system planet, a balloon-borne planetary atmospheric spectral telescope (PAST) is designed with 0.8-m aperture in spectral range from 280 nm to 680 nm will be floated at 35–40 km altitude to observe and investigate the global space environment of Mercury, Venus, Mars, and Jupiter. The telescope is designed by Changchun Institute of Optics, Fine Mechanics and Physics, Chinese Academy of Sciences (CIOMP, CAS), and supported by the Strategic Priority Research Program of Chinese Academy of Sciences, that is the Scientific Experimental system in Near-SpacE (SENSE). The telescope is mainly supported by a Ritchey-Chrétien optical system which can achieve 0.5" angular resolution observation, and the optical system has the function of focusing and stabilizing. The telescope is combined with a two-dimension rotate platform to achieve planetary atmospheric imaging in long exposure time. This paper mainly introduces the PAST scheme briefly.

Site-selective synthesis of C-7 arylated indolines has been achieved via oxidative arylation of indolines with arylsilanes under Rh(III)-catalyzed C–H activation of indolines by using CuSO4 as a co-oxidant. This transformation has been explored for a wide range of substrates under mild conditions.

The High-Resolution Imaging Camera (HiRIC) is one major payload of China’s first Mars exploration mission, and its main objective is to obtain the detailed observation images of the key areas on the Martian surface. In this paper, the leading group of HiRIC shows a full blueprint of the HiRIC. The HiRIC can achieve a high resolution (0.5 m at an altitude of 265 km) with a wide swath width of 9 km. The HiRIC adopts an Off-Axis Three-Mirror Astigmatic (TMA) optical system with a focal length of 4640 mm, an F-number of 12 and a Field of View (FOV) of 2° × 0.693°. In order to reduce the instrument weight, carbon-based material is widely used in the opto-mechanical structure which is in ultra-lightweight design, thus, a light-weight camera with a total mass of 42 kg is obtained. The Time Delay and Integration (TDI) Charge Coupled Devices (CCDs) and Complementary Metal-Oxide-Semiconductor Transistor (CMOS) detectors are all set on the imaging plane to achieve the push-broom imaging and frame imaging, respectively. And the high Signal-to-Noise Ratio (SNR) >100:1 can achieve in multi observation types for various scientific imaging tasks. After 4-year design and fabricate, the HiRIC has been assembly. The testing results show that the instrument is in good condition, and the Modulation Transfer Function (MTF) can achieve 0.18 at Nyquist frequency. The HiRIC can achieve a well image on China first Mars exploration mission.

The palladium-catalyzed oxidative arylation of indolines with arylsilanes at the C-7 position via C–H bond activation has been reported. This transformation has been applied to a wide range of substrates. It represents a facile access to C-7 arylated indolines, which can be conveniently transformed into C-7 arylated indoles.

Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents, the pathogenesis of which remain largely unknown. Small ubiquitin-like modifier (SUMO)-Specific Protease 2 (SENP2) has been reported to serve as a tumor suppressor in hepatocellular carcinoma cells. The aim of the present study was to investigate the critical role of SENP2 in OS cells. Using reverse transcription-quantitative polymerase chain reaction and western blot assays, it was observed that SENP2 was significantly downregulated in clinical OS tissues compared with adjacent normal samples. Ectopic expression of SENP2 resulted in the suppression of proliferation, migration and invasion in OS cells, whereas SENP2 knockdown by CRISPR-Cas9-based gene editing had the opposite effect. SENP2 is associated with the proteasome-dependent ubiquitination and degradation of SRY-box-9 (SOX9). SOX9 silencing impaired SENP2-depletion-induced accelerated cell growth and migration. Together, these results suggest that SOX9 is a critical downstream effector of the tumor suppressor SENP2 in OS.

Currently, the design and construction of an intelligent stimuli-responsive gel system is still a significant challenge. We present here a new gel system from which the formation of heat-set gels, conventional gels and irreversible heat-set gels can be achieved in aromatic solvents. This gel system is based on two-component gelators containing a succinamic acid derivative (SAD) and a primary alkyl amine (R-NH2). With the increase of temperature to 85 °C, a rarely reported reversible heat-set gel (gel formation with the increase of temperature) is afforded. Upon addition of fatty acids into two-component gelators, a conventional gel (gel formation with the decrease of temperature) is formed. When the fatty acid is replaced with dicarboxylic acid, a new heat-set gel is generated, which is irreversible and thermally super-stable. X-ray diffraction analysis reveals that the formation of a reversible heat-set gel relies on electrostatic interactions, hydrogen bonds, and hydrophobic interactions. These two-component gelators show a perfect gel system for the formation of diverse gels including heat-set gels, conventional gels and irreversible heat-set gels. The tunable strategy demonstrated in this letter may provide a new way for creation of more functional gels in gel science.

Changes in pig fertility have occurred as a result of domestication, but are not understood at the level of genetic variation. To identify variations potentially responsible for prolificacy, we sequenced the genomes of the highly prolific Taihu pig breed and four control breeds. Genes involved in embryogenesis and morphogenesis were targeted in the Taihu pig, consistent with the morphological differences observed between the Taihu pig and others during pregnancy. Additionally, excessive functional non-coding mutations have been specifically fixed or nearly fixed in the Taihu pig. We focused attention on an oestrogen response element (ERE) within the first intron of the bone morphogenetic protein receptor type-1B gene ( BMPR1B ) that overlaps with a known quantitative trait locus (QTL) for pig fecundity. Using 242 pigs from 30 different breeds, we confirmed that the genotype of the ERE was nearly fixed in the Taihu pig. ERE function was assessed by luciferase assays, examination of histological sections, chromatin immunoprecipitation, quantitative polymerase chain reactions, and western blots. The results suggest that the ERE may control pig prolificacy via the cis-regulation of BMPR1B expression. This study provides new insight into changes in reproductive performance and highlights the role of non-coding mutations in generating phenotypic diversity between breeds.

Finger vein recognition refers to a recent biometric technique which exploits the vein patterns in the human finger to identify individuals. Finger vein recognition faces a number of challenges. One critical issue is the performance of finger vein recognition system. To overcome this problem, a finger vein recognition algorithm based on one kind of subspace projection technology is presented. Firstly, we use Kapur entropy threshold method to achieve the purpose of intercepting region of finger under contactless mode. Then the finger vein features were extracted by 2DPCA method. Finally, we used of nearest neighbor distance classifier for matching. The results indicate that the algorithm has good recognition performance.

Presented in this communication are four metal complexes based on 2-propyl-4,5-dicarboxylate-imidazole (H3PIDC), including two Co(II) coordination compounds, [Co(H2PIDC)2(H2O)2] · 4H2O (1) and 2[Co(H2PIDC)2(H2O)2] · 5H2O (2), as well as two Zn(II) coordination compounds, [Zn(H2PIDC)2(H2O)2] · 4H2O (3) and 2[Zn(H2PIDC)2(H2O)2] · 7H2O (4). They contain the same coordinated unit of [M(H2PIDC)2(H2O)2] (M = Zn or Co). Interestingly, among these four complexes, 1 and 2, or 3 and 4 crystallized in different space group, which may be related with the number of the crystallized H2O molecules.

The U.S.A has launched the Mars Orbiter. It brought a high resolution imaging science equipment, and that is the High Resolution Imaging Science Experiment camera(HIRISE). HIRISE is 0.5 m reflecting telescope, which is the highest one ever carried on a deep space mission, and it has a resolution of 1 microradian (rad), or 0.3 m from an altitude of 300 km. HIRISE can investigate deposits and landforms resulting from geologic and climatic processes and assist in the evaluation of candidate. As a high degree of lightweight ultra-high resolution camera, the design of its FPA is unparalleled .Therefore we should study and learn it carefully. In this article, first of all we discuss and analyze the characters of the HIRISE FPA in terms of the structural layout, material selection, splicing of the CCD, the CCD package, electronics, processing and transmission, and thermal control measures implementation. Next we put forward the design method of highly lightweight space optical remote sensor FPA combined with the characters of the HIRISE FPA, which can provide a reference to the design of the FPA for some space remote sensings. (2013) Trans Tech Publications, Switzerland.

Cocrystallizations of melamine (ma) with m -sulfophenylphosphonic acid (sppH 3 ) from water in different molar ratios (2:1 and 4:1) offer [(maH) 2 (sppH)]·3H 2 O ( 1 ) and [(maH) 3 (spp)(ma)]·12H 2 O ( 2 ), respectively. Structure analysis reveals that two very intricate hydrogen-bonded networks are formed in them, with two or three protons of the m -sulfophenylphosphonic acid being transferred to melamine. The resultant (sppH) 2− or (sppH) 3− anion can form as many as 12 or 14 hydrogen bonds with melamine and water molecules, showing a very high hydrogen-bonding capability.

The focal plane assembly is one of the most important components of Space camera, whose splicing accuracy the camera imaging quality. Through the analysis of CCD's splicing methods, the focal plane of space camera was staggered lap compact mechanical design, carried out high-precision splicing and testing. While splicing the image processing technology is used to CCD's pixel labeling's quantization processing. The ultimate purpose is to eliminate possible errors which due to human visual impact on the stitching accuracy and improve stitching accuracy based on the focal plane's character. The results show that the focal plane of CCD chip overlap error is less than 3 μm, the two rows of CCD in the parallel error is less than 3 μm, the coplanar error is less than 5 μm. Finally, according to the analysis of the image obtained from the imaging test on the ground, the camera image stitching results were coincided with the test results, which proved that the method is feasible and accurate. All the results show ...

Considering the feasibility of the application of GIS technology and multimedia technology in campus emergency preparedness managing platform system, this paper discusses the overall design for visual campus emergency preparedness management system, where the principles of prevention and treatment for campus public emergency and this emergency preparedness visualization management system works are proposed. Then, various multimedia animation preparedness is realized by using Flash soft. By the way of analyzing various data of GIS, using professional software tool of GIS-MapInfo, taking Scilab as platform, we realize the functions of the intelligent electronic map design for HEU campus. This platform can enable visualized query and data searching, such as Eagle eye location, target finding, the shortest path searching, network communication and preparedness videos playing.

The palladium-catalyzed oxidative arylation of indolines with arylsilanes at the C-7 position via C–H bond activation has been reported. This transformation has been applied to a wide range of substrates. It represents a facile access to C-7 arylated indolines, which can be conveniently transformed into C-7 arylated indoles.

To develop a Jingcen DY-1 type spraying tanker for Oncomelania hupensis snail control and evaluate its effect of field application as well as the cost.The currently available tractor was used as a vector, and the mechanical and electrical equipments and containers were integrated with shafts, pipelines and electric lines to produce a spraying tanker for snail control, with the functions of carrying people and molluscicides, generating electric power and getting water, mixing stocking solutions, adjusting molluscicide solutions evenly, and spraying drugs. The volume of the molluscicide solution, flow rate of water injection, and the flow rate, range and advance speed of the spray gun were tested, and the solution concentrations of molluscicide in the tanker and at the muzzle of the spray gun at different time were detected. Meanwhile, the molluscicidal effect and cost of the spraying tanker were analyzed by the field test.The volume of the liquid storage pot of the Jingcen DY-1 type spraying tanker was 1 800 L, the flow rate of water injection was 400 L/min, the flow rate and the spray range of the standard spray gun were 110-200 L/min and 19.70-23.50 m, respectively, the efficiency of drug spraying of the spraying tanker was 6 000 m/h, and the ratio of spray width (m) to march speed (m/min) was 1:200. When 5 min post mother liquid recirculating, the average concentration of the molluscicide at the upper-, middle- and lower-layers of the liquid storage pot was (1030.39 ± 43.00) mg/L, with a variation coefficient of 4.17%. The average concentration of the molluscicide in the spraying process (spraying for 2, 4, 6, 8, 9 min) was (953.00 ± 68.87)mg/L, with a variation coefficient of 7.22%. The concentration of the residual drug in the liquid storage pot post spraying was 1 000.43 mg/L, which reached the effect concentration for snail control. After spraying for 7 days in the field, the average density of living snails reduced by 88.20% as compared to that before spraying, and the adjusted mortality of snails was 87.65%. The unit cost of Jingcen DY-1 spraying tanker was 0.086 7 Yuan/m². which reduced by 58.20% as compared to that of the conventional spraying tanker.Jingcen DY-1 type spraying tanker for snail control which integrates various equipments together can effectively control the concentration and dose of the molluscicide, and the machine is labor-saving, efficient, economic and well adapted, and is worthy to be widely applied.

Supramolecular isomerism for coordination networks refers to the existence of different architectures having the same building blocks and identical stoichiometries. For a given building block, different arrangements can lead to the formation of a series of supramolecular isomers. Two one-dimensional CoIIcoordination polymers based onN,N′-bis(pyridin-3-yl)oxalamide (BPO), bothcatena-poly[[[dichloridocobalt(II)]-bis[μ-N,N′-bis(pyridin-3-yl)oxalamide-κ2N:N′]] dimethylformamide disolvate], {[CoCl2(C12H10N4O2)2]·2C3H7NO}n, have been assembled by the solvothermal method. Single-crystal X-ray diffraction analyses reveal that the two compounds are supramolecular isomers, the isomerism being induced by the orientation of the dimethylformamide (DMF) molecules in the crystal lattice.

Two cadmium(II) metal–organic frameworks based on two mixed ligands of HBTA and H2BDC, [Cd5(BTA)6(BDC)2(DMF)4(H2O)2]n·n(2DMF·H2O) (1) and [Cd7(BTA)2(BDC)6(DMF)8]n·2nDMF (2) (HBTA = 1,2,3-benzenetriazole; H2BDC = 1,4-benzenedicarboxylic acid), have been prepared through methods of liquid to liquid diffusion and solvothermal reaction, respectively. The results of single-crystal X-ray diffraction analyses indicate that both MOFs are constructed from cadmium clusters. In 1, six BTA– anions connect five Cd(II) ions to generate a tetrahedral Cd5 cluster, which further links with four equivalent Cd5 clusters through four BDC2– bridges, forming a (4,4)-connected two–dimensional (2D) layer structure. In 2, each BTA– anion connects three Cd(II) ions to generate a triangular Cd3 cluster, which further links with four Cd3 clusters and two 3-connected BDC2– anions, forming a (3,6)-connected three-dimensional (3D) framework. The results of photoluminescent measurements illustrate that in the solid state, both 1 and 2 c...

General materials can satisfy the structure strength requirement of space effective payload easily. But it can hardly satisfy the structure stiffness requirement of space payload. Carbon fiber composite has many excellent properties, such as high relative strength, high relative stiffness, small expansion coefficient, good fatigue resistance and excellent vibration resistance. It can be used to make space products. Firstly, this paper discussed the properties of carbon fiber composite material. Compared with common materials, such as aluminum alloy and titanium alloy, carbon fiber composite material is more suitable for applications of space instruments. Secondly, the metal part embedded technique of carbon fiber composite structure was studied. According to the carbon fiber composite structure of a space camera frame, a few structure forms of embedded part ware studied. A space camera frame of carbon fiber composite was designed and manufactured. Finally, finite element analysis and mechanical tests on the space camera frame was carried out. The results reveal that the characteristic frequency of carbon fiber composite frame is up to 104Hz.The space camera frame is of high stiffness and dimensional stability.

Ni-Bi alloys were selected to bond to ZrO2 ceramic by diffusion bonding at atmosphere for researching their bondability. The Ni-Bi alloys were Ni-xmass%Bi (x=0, 0.5, 1.0, 1.5, 2.0, 2.5, 3.0) and ZrO2 ceramic was Z201N. The bonding was carried out at 973 K, 1037 K and 1173 K for 3.6 ks, 5.4 ks, 7.2 ks, 9.0 ks and10.8 ks under the pressure of 2 MPa, 4 MPa, 6 MPa, 8 MPa, 10 MPa and 12 MPa. The bonding strength was examined by the shear fracture test from room temperature to high temperature. The results indicate that pure nickel could be bonded to ZrO2. Adding bismuth into nickel alloy could obviously improved shear strength at room temperature. The optimum content of bismuth was 2%. The shear strength of vacuum-free diffusion bonding joint was higher than that of vacuum diffusion bonding joint. ZrO2/Ni-2Bi joint was bonded at 1173 K for 7.2 ks under 8 MPa, which shear strength was up to 22 MPa until the test temperature of 873 K.

The support structure of large aperture mirror of space remote sensor is the key of the space remote sensor development. In this paper, the size of the large aperture mirror is Φ700mm,which is supported in the back of mirror with 3 points ,the composite structure of ball joint and flexible groove is adopted in support structure which can guarantee the mirror surface satisfy the requirement of optical design under the coupled load of gravity and heat. At the same time, the mirror subassembly should have a high enough stiffness through the reasonable lightweight to ensure the camera in transportation and launch process can withstand severe vibration condition. In order to validate the rationality of the design,the finite element analysis is done to the mirror subassembly,which indicates that the shape error variation of mirror RMS is better than λ/50 and PV is better than λ/10 in the coupling load of gravity and heat,and the first natural frequency of the mirror subassembly is higher than the design requirements. Dynamics calculation results of mirror subassembly consistent with mechanics experiment results；the surface precision of the mirror subassembly obtained from the ZYGO interferometer consistent with the results of finite element analysis and meets the design requirements.

An extremely stable hydrogen-bonded organic framework, HOF-8, was fabricated. HOF-8 is not only thermally stable but also stable in water and common organic solvents. More interestingly, desolvated HOF-8 exhibits high CO2 adsorption as well as highly selective CO2 and C6H6 adsorption at ambient temperature.

To evaluate the effect of surgical manipulation on the dissemination of cancer cells into blood circulation in patients with gastric cancer and to analyze its risk factors.This study included 45 consecutive patients with gastric cancer undergoing curative resection and 13 control cases (10 healthy persons and 3 patients with peptic ulcer receiving gastrectomy). Peripheral blood was obtained preoperatively and just after surgical manipulation. The mRNA levels of carcinoembryonic antigen (CEA) from the blood samples were assayed by reverse transcription-polymerase chain reaction(RT-PCR) and compared between the 2 groups.CEA mRNA was negative in all control cases. Of the 45 gastric cancer patients, the preoperative positive rate of CEA mRNA was 8.9%, while the postoperative positive rate was 48.9%, which was significantly higher than that of preoperation (P=0.000). Multivariable Logistic regression analysis showed that operative duration (P=0.014) and tumor depth (P=0.010) were independent risk factors for cancer cell dissemination. Furthermore, the operative duration in patients with positive postoperative CEA mRNA was markedly longer than that in patients with negative postoperative CEA mRNA (P=0.000), and positive rate of postoperative CEA mRNA in advanced gastric cancer was higher compared with that in early gastric cancer (P=0.034).Surgical manipulation of curative gastrectomy can provoke dissemination of cancer cells into blood circulation, and the operative duration and tumor invasion depth may be 2 of the risk factors for cancer cell dissemination.

The low-molecular-weight chitosan-Ce(III) complexes were synthesized at pH value 1-2 and characterized by UV spectrum, fluorescence spectrum, FTIR spectrum and 1H NMR spectrum. Its coordination mechanism was also investigated. The results showed that Ce(III) was coordinated with -OH group instead of -NH2 group of low-molecular-weight chitosan.

To study the alkaloid constituents of the root of Lindera angustifolia Cheng.The constituents were isolated and purified by column chromatography and the structures were characterized by spectral analysis.Seven aporphine alkaloids, laurotetanine (I), N-methyllaurotetanine (II), boldine (III), isoboldine (IV), norboldine (V), N-ethoxycarbonyllaurotetanine (VII) and a quaternary isoquinoline alkaloid, magnocurarine (VI), were isolated and identified. The structure of VII was further identified by semi-synthesis with I as starting material.All compounds were obtained from this plant for the first time and compound VII was found as a naturally occurring compound for the first time.

Lindera angustifolia Chen is a folk medicine used for the treatment of contusions-induced swelling, rheumatic pains and bellyache in south and the middle part of China. Phytochemical studies showed that aporphine and benzyltetrahydroisoquinoline alkaloids are the characteristic constituents of this plant. In this study, we evaluated the antinociceptive and free radical scavenging properties of six aporphine and two benzyltetrahydroisoquinoline alkaloids isolated from the root of Lindera angustifolia. All alkaloids except magnocurarine exhibited remarkable radical scavenging effects (36–90% scavenging at 25–100 μg/ml) in DPPH radical scavenging test, among them norisocorydine showed the hightest activity (SC50: 14.1 μg/ml). Antinociceptive activities were tested by using acetic acid-induced writhing and formalin test at dose of 20 mg/kg. Norisocorydine exhibited the highest antinociceptive ability with 83.5% writhing inhibition. Boldine, norboldine showed significant antinociceptive activity with 76.3% and 74.6% writhing inhibition respectively. Indomethacin was used as positive control, which showed 67.8% writhing inhibition at dose of 10 mg/kg. Most of the compounds, except N-ethoxycarbonyllaurotetanine and magnocurarine, could significantly inhibit the phase I reaction (P

A key and difficult step of echo signal recognition is to extract the effective characteristic of target reflection signal. The research shows that it can limit Wigner's feature extraction for single frequency and single time. For these reasons, we have posed time-frequency analytical method based on Wigner's distribution transformation in the paper. Two kinds of targets True and False are classified by the method. We apply Fuzzy ART network to test the classification ability. When the ratio of signal and reverberation isn't less than 6 dB, the correct recognition ratio can arrive 81% to original echo signal.

Today, there's a synergy beginning to form among neural nets (NNs), fuzzy logic (FL) and genetic algorithms (GAs). This paper reviews developments in this respect. Many designs of knowledge-based and associated learning systems using the combination of NNs and FL abilities have been presented. Some methods for the integration of GAs with fuzzy systems are described. Afterwards, work on hybrid systems of GAs and NNs is discussed. Finally, some advantages obtained through the fusion of the FL, NNs and GAs are emphasized, and possible ways of combining the three are developed.

In the title polymer, {[Cu(C(8)H(12)N(2)O(6)P(2))]·2H(2)O}(n), the geometry of the five-coordinate Cu(II) ion can best be described as slightly distorted square-pyramidal formed by one N and two O atoms of an N(CH(2)PO(3)H)(2) group and one N atom from a pyridine ring. The elongated apex of the pyramid is occupied by one O atom from a third diphospho-nate ligand. The inter-connection of Cu(2+) ions by the diphospho-nate ligands results in the formation of a double-chain array along the b axis, in which the two sub-chains are inter-locked by pairs of PO(3) groups. The outside of each sub-chain is decorated by other PO(3) groups. These double chains are further assembled into a three-dimensional supra-molecular architecture via a large number of O-H⋯O hydrogen bonds between the phospho-nate groups and lattice water mol-ecules.

A three-dimensional tetrazole-based Cd(II) metal–organic framework containing rare large Cd8 and Cd23 secondary building units has been hydrothermally prepared through in situ metal/ligand reaction, which shows an unprecedented (4,10)-connected topology net.