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1. The incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer in Japanese hospitals: A large‐scale clinical study

Author

Nobuki Ichikawa, Shigenori Homma, Tohru Funakoshi, Keisuke Obuchi, Takahiro Ohshima, Kazuhito Uemura, Hirofumi Kon, Yosuke Ohno, Ryoichi Yokota, Akinobu Taketomi, and Hokkaido Colorectal Surgical Research Group Collaborative

Subjects
colorectal neoplasms, ischemic heart disease, laparoscopy, stroke, thrombosis, Surgery, RD1-811, Diseases of the digestive system. Gastroenterology, RC799-869
Abstract

Abstract Aim The aim of this retrospective study was to investigate the incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer. Methods This study involved 2017 patients with stages 0‐III colorectal cancer who underwent laparoscopic surgery at 17 Japanese hospitals between January 2010 and December 2013. We assessed the incidence of postoperative cardiovascular thrombotic and haemorrhagic complications. Results Laparoscopic surgeries were performed in 1152 men and 865 women with 1405 colon and 612 rectal cancers, respectively. Overall, 3%, 38%, 17%, 8%, and 9% of patients had comorbidities of heart failure, high blood pressure, diabetes, history of stroke, and vascular disease, respectively. Antithrombotic agents were being consumed by 17% of patients. The types (and perioperative rest periods) of the antithrombotic agents were aspirin in 58% (18.6 days), clopidogrel in 19% (21.1 days), cilostazol in 13% (13.3 days), and warfarin potassium in 21% (14.6 days) of cases with antithrombotic agents. Surgical time and blood loss in the total cohort were 234 minutes and 56 mL. Four cases (0.2%) had cardiovascular thrombotic complications, including one severe cardiac infarction and one stroke with major sequelae (CHADS2 scores were 2 points in both cases). Hemorrhagic complications occurred in 19 cases (0.9%). In particular, the incidence of the major gastroduodenal haemorrhagic ulcer was higher in cases with antithrombotic agents than without them (0.05% vs 0%, P = .02). Conclusion The incidence of cardiovascular thrombotic complications was rare, although severe cardiac infarction and stroke could occur even after minimally invasive surgery in colorectal cancer.

Published
2022
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3. The incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer in Japanese hospitals: A large‐scale clinical study

Author

Nobuki, Ichikawa, Shigenori, Homma, Tohru, Funakoshi, Keisuke, Obuchi, Takahiro, Ohshima, Kazuhito, Uemura, Hirofumi, Kon, Yosuke, Ohno, Ryoichi, Yokota, Akinobu, Taketomi, and Tsunehiko, Morita

Subjects
laparoscopy, Gastroenterology, Surgery, colorectal neoplasms, ischemic heart disease, stroke, thrombosis
Abstract

Aim The aim of this retrospective study was to investigate the incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer. Methods This study involved 2017 patients with stages 0-III colorectal cancer who underwent laparoscopic surgery at 17 Japanese hospitals between January 2010 and December 2013. We assessed the incidence of postoperative cardiovascular thrombotic and haemorrhagic complications. Results Laparoscopic surgeries were performed in 1152 men and 865 women with 1405 colon and 612 rectal cancers, respectively. Overall, 3%, 38%, 17%, 8%, and 9% of patients had comorbidities of heart failure, high blood pressure, diabetes, history of stroke, and vascular disease, respectively. Antithrombotic agents were being consumed by 17% of patients. The types (and perioperative rest periods) of the antithrombotic agents were aspirin in 58% (18.6 days), clopidogrel in 19% (21.1 days), cilostazol in 13% (13.3 days), and warfarin potassium in 21% (14.6 days) of cases with antithrombotic agents. Surgical time and blood loss in the total cohort were 234 minutes and 56 mL. Four cases (0.2%) had cardiovascular thrombotic complications, including one severe cardiac infarction and one stroke with major sequelae (CHADS2 scores were 2 points in both cases). Hemorrhagic complications occurred in 19 cases (0.9%). In particular, the incidence of the major gastroduodenal haemorrhagic ulcer was higher in cases with antithrombotic agents than without them (0.05% vs 0%, P = .02). Conclusion The incidence of cardiovascular thrombotic complications was rare, although severe cardiac infarction and stroke could occur even after minimally invasive surgery in colorectal cancer.

Published
2021

4. Surgically Diagnosed Primary Hepatic Angiosarcoma

Author

Urara Baba, Shuichi Muto, Yoko Taya, Seiji Tsunematsu, Tomoaki Naka, Rui Sasaki, Hiroki Oi, Toshio Kimura, Yuki Tsukamoto, Yukio Ohara, Kazuhito Uemura, and Takashi Kitagataya

Subjects
Surgical resection, medicine.medical_specialty, diagnosis, Treatment outcome, Case Report, hepatosarcoma, hemangiosarcoma, 03 medical and health sciences, 0302 clinical medicine, Biomarkers, Tumor, Internal Medicine, medicine, Humans, Effective treatment, primary hepatic angiosarcoma, Good outcome, neoplasms, Aged, business.industry, Liver Neoplasms, Advanced stage, surgical resection, General Medicine, Hepatic Angiosarcoma, medicine.disease, digestive system diseases, Rare tumor, Treatment Outcome, Hemangiosarcoma, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, Radiology, business
Abstract

Primary hepatic angiosarcoma is a rare tumor originating from endothelial cells in the liver and accounts for approximately 1% of all hepatic malignant tumors. It is difficult to diagnose due to the lack of specific symptoms or tumor markers. No effective treatment exists, but complete surgical resection may achieve a good outcome. Since most primary hepatic angiosarcomas are already at an advanced stage at diagnosis, few reports describe tumors smaller than 2 cm. We report a case of surgery for a 1.7-cm sized primary hepatic angiosarcoma. Further studies are required to improve the preoperative diagnosis of primary hepatic angiosarcoma.

Published
2018

5. Surgeons' fear of getting infected by COVID19: A global survey

Author

An, Yongbo, primary, Bellato, Vittoria, additional, Konishi, Tsuyoshi, additional, Pellino, Gianluca, additional, Sensi, Bruno, additional, Siragusa, Leandro, additional, Franceschilli, Marzia, additional, Sica, Giuseppe S, additional, Kefleyesus, A, additional, Hoofwijk, A G M, additional, Eldaly, Abdullah Sami, additional, Gonzalez, Abel, additional, Jawad, Adraoui, additional, Jooma, Ahmad, additional, Hafez, Ahmed Mousa, additional, Rubio, Ainhoa Valle, additional, Landaluce-Olavarria, Aitor, additional, Wu, Aiwen, additional, Nagatsu, Akihisa, additional, Inoue, Akira, additional, Kanamoto, Akira, additional, Ouchi, Akira, additional, El-Hussuna, Alaa, additional, Vazquez-Melero, Alba, additional, Wolthuis, Albert M, additional, Peral, Alberto M, additional, Lozano, Alejandra Cruz, additional, Efremov, Aleksandr, additional, Ryasantsev, Aleksandr V, additional, Di Giorgio, Alessandra, additional, Parente, Alessandro, additional, Tamburrini, Alessandro, additional, Alò, Alessio, additional, Forero-Torres, Alexander, additional, Vahrmeijer, Alexander L, additional, Varabei, Alexander, additional, Hinojosa, Siles, additional, Balkan, Ali Zeynel Abidin, additional, Frontali, Alice, additional, Oleg, Alikin, additional, Soler-Silva, Álvaro, additional, Makni, Amin, additional, André, Ana, additional, Cabrera, Ana María García, additional, Fernández, Ana María Gonzalez, additional, Minaya-Bravo, Ana M, additional, Rodríguez-Sánchez, Ana, additional, Musina, Ana-Maria, additional, Pangeni, Anang, additional, Zolotko, Anastasia, additional, Tonoyan, Andranik, additional, Balla, Andrea, additional, Belli, Andrea, additional, Cavallaro, Andrea, additional, Chierici, Andrea, additional, Divizia, Andrea, additional, Bucci, Andrea Fares, additional, Salido, Andrea Jiménez, additional, Morini, Andrea, additional, Muratore, Andrea, additional, Vignali, Andrea, additional, Chitul, Andrei, additional, Sebastian, Diaconescu Andrei, additional, Pcolkins, Andrejs, additional, Shchegolev, Andrey, additional, Hollenbeck, Andrew, additional, Wisneski, Andrew, additional, Iossa, Angelo, additional, D'Amore, Anna, additional, Hunter, Anndrew, additional, Hesketh, Anthony J, additional, La Brocca, Andrea, additional, Spinelli, Antonino, additional, Caires, Antonio, additional, D'Alessandro, Antonio, additional, Correo, Antonio Francisco Sanchís López, additional, Macrì, Antonio, additional, Navarro-Sánchez, Antonio, additional, Pronk, Apollo, additional, Akunc, Aram, additional, Mehri, Arash, additional, Pelta, Arie, additional, Papadopoulos, Aristeidis, additional, Kechagias, Aristotelis, additional, Rashid, Arshad, additional, Ramazanov, Artur, additional, Chandio, Ashfaq, additional, Kohyama, Atsushi, additional, Nishimura, Atsushi, additional, Ohkawa, Atsushi, additional, Dulskas, Audrius, additional, Jamal, Aun, additional, Mariani, Aurora, additional, Unal, Ayse Gizem, additional, Karagoz, Ayse, additional, Ozkan, Bahar Busra, additional, Salih, Barham, additional, Gülcü, Baris, additional, Pessia, Beatrice, additional, Martin-Perez, Beatriz, additional, Ielpo, Benedetto, additional, Tulelli, Berenice, additional, Yang, Bin, additional, Mhamed, Boumadani, additional, Murphy, Brenda, additional, Pirozzi, Brunella Maria, additional, Langenhoff, Bs, additional, Belevi, Bulent, additional, Güney, Burak, additional, Ng, Caecilia, additional, Rueda, Camilo, additional, Roxburgh, Campbell S, additional, Feo, Carlo V, additional, Ferrari, Carlo, additional, Gazia, Carlo, additional, Pratesi, Carlo, additional, Ratto, Carlo, additional, Santacruz, Carlos Cerdán, additional, Arroyave, Carlos Rodolfo Martinez, additional, Macias, Carlos, additional, Fernandez, Carlota Garcia, additional, Fernandez, Carmen Cagigas, additional, Curtis-Martinez, Carolina, additional, Fortmann, Caroline, additional, Kim, Caroline, additional, Galeano, Catalina Uribe, additional, Barroso, Catarina, additional, Baldi, Caterina, additional, Foppa, Caterina, additional, Formisano, Cesare, additional, Li, Changzai, additional, Ding, Chao, additional, Wang, Chenyu, additional, Iacusso, Chiara, additional, Yang, Chongwei, additional, Pizzera, Christian, additional, Skias, Christoph, additional, Chouliras, Christos, additional, Liakos, Christos, additional, Matsuda, Chu, additional, Wu, Chun-yi, additional, Ozaslan, Cihangir, additional, Tanda, Cinzia, additional, Tommaso, Cipolat Mis, additional, Dagorno, Claire, additional, Ramos, Claudia Patricia Arellano, additional, Arcudi, Claudio, additional, Coco, Claudio, additional, Morales, Cleotilde Mateo, additional, Ali, Mujahid Zulfiqar, additional, Lozano, Coral Cózar, additional, Sala, Corrado, additional, Leo, Cosimo Alex, additional, Scarpa, Cosimo Riccardo, additional, Ferro, Cristian Varela, additional, Fernandez, Cristina Mosquera, additional, Morales-Garcia, D, additional, Nakano, Daisuke, additional, Cristian, Daniel, additional, Hechtl, Daniel, additional, Cánovas, Daniel Triguero, additional, Calabrese, Daniela, additional, Rega, Daniela, additional, Ferraro, Daniele, additional, Morezzi, Daniele, additional, Sommacale, Daniele, additional, Brogden, Danielle, additional, Miskovic, Danilo, additional, Merlini, David, additional, Pertile, Davide, additional, Coniglio, Denise, additional, Zhu, Dexiang, additional, Wu, Dianwen, additional, Coletta, Diego, additional, Rubio, Diego Ramos, additional, Sasia, Diego, additional, Fillipov, Dmitry, additional, Russiello, Domenico, additional, Dardanov, Dragomir, additional, Consten, E C J, additional, Smolskas, Edgaras, additional, Muttillo, Edoardo Maria, additional, Jones, Edward, additional, Sunami, Eiji, additional, Etienne, El-Helou, additional, Chalkiadaki, Elena, additional, Giacomelli, Elena, additional, Karbovnichaya, Elena, additional, Ruiz-Úcar, Elena, additional, Guaitoli, Eleonora, additional, Samadov, Elgun, additional, Jovine, Elio, additional, Treppiedi, Elio, additional, Vaterlini, Elisa Maria, additional, Zambaiti, Elisa, additional, Moggia, Elisabetta, additional, Coetzee, Elmi, additional, Chisari, Emanuele, additional, D'Errico, Emanuele, additional, Ciofic, Emilia, additional, Peña, Emilio, additional, Kurt, Emine, additional, Balık, Emre, additional, Gunay, Emre, additional, Sivrikoz, Emre, additional, Andolfi, Enrico, additional, Araimo, Enrico, additional, Lucci, Enrico, additional, Opocher, Enrico, additional, Pinotti, Enrico, additional, Rubino, Enrico, additional, Reyhan, Enver, additional, Mazzotta, Erica, additional, Navarro, Ernesto Barzola, additional, El-Helou, Etienne, additional, Licardie-Bolaños, Eugenio, additional, Porto, Eva Iglesias, additional, Contreras, Evelyn, additional, Boerma, Evert-Jan, additional, Cianchi, Fabio, additional, Marino, Fabio, additional, Uggeri, Fabio, additional, Han, Fanghai, additional, Calculli, Federica, additional, Falaschi, Federica, additional, Ghignone, Federico, additional, Perrone, Federico, additional, Borghi, Felice, additional, García, Felipe, additional, Agresta, Ferdinando, additional, Cananzi, Ferdinando Carlo Maria, additional, Mendoza-Moreno, Fernando, additional, Cengiz, Fevzi, additional, Almeida, Filipe Macedo, additional, Baracchi, Filippo, additional, Carannante, Filippo, additional, La Torre, Filippo, additional, Fernandes, Flavio, additional, Friedmacher, Florian, additional, Grama, Florin, additional, Carissimi, Francesca, additional, Pecchini, Francesca, additional, Bianco, Francesco, additional, Colombo, Francesco, additional, Ferrara, Francesco, additional, Litta, Francesco, additional, Carrano, Francesco Maria, additional, Martignoni, Francesco, additional, Tasselli, Francesco Menegon, additional, Milone, Francesco, additional, Pata, Francesco, additional, Sammartino, Francesco, additional, Zambianchi, Francesco, additional, Barragan, Francisco, additional, Herrero, Francisco, additional, Schlottmann, Francisco, additional, Den Boer, Frank C, additional, Pfeffer, Frank, additional, Fujita, Fumihiko, additional, Navarra, G, additional, Herrera-Almario, Gabriel, additional, Pozzo, Gabriele, additional, Capolupo, Gabriella Teresa, additional, Van Ramshorst, Gabrielle H, additional, Liscia, Gadiel, additional, Gallo, Gaetano, additional, Asawa, Ganesh, additional, Wang, Gaoxiang, additional, Raiyani, Gaurang, additional, Beets, Geerard, additional, Naval, Gemma Sugrañes, additional, Jin, Genfeng, additional, Chang, George J, additional, Saakian, George, additional, Kahane, Gerardo, additional, Borroni, Giacomo, additional, Lo Secco, Giacomo, additional, Baiocchi, Gian Luca, additional, Baronio, Gianluca, additional, Pagano, Gianluca, additional, Pattacini, Gianmaria Casoni, additional, Lisi, Giorgio, additional, Milito, Giovanni, additional, Sinibaldi, Giovanni, additional, Serrao, Giuditta, additional, Bagaglini, Giulia, additional, Sarro, Giuliano, additional, Brisinda, Giuseppe, additional, Candilio, Giuseppe, additional, Mangiameli, Giuseppe, additional, Giuliani, Giuseppe, additional, Martin-Martin, Gonzalo Pablo, additional, Bodzin, Gordon, additional, Leon, Graat, additional, Mackay, Graham, additional, Vasil, Granila, additional, Palmisano, Graziano, additional, Giovanna, Grella Maria, additional, Fernández, Guadalupe Campos, additional, Steingel, Guillermo Berrones, additional, Zhang, Guoyun, additional, Choi, Gyu Seog, additional, Chen, Haipeng, additional, Hirose, Hajime, additional, Kayano, Hajime, additional, Ulgur, Hanife Seyda, additional, Impellizzeri, Harmony, additional, Ariola, Hasani, additional, Liu, Heli, additional, Medina, Heriberto, additional, Miyauchi, Hideaki, additional, Takahashi, Hidekazu, additional, Hayashi, Hideki, additional, Ishikawa, Hideki, additional, Ishida, Hideyuki, additional, De Vries, Hilbert, additional, Ulman, Hilmican, additional, Kon, Hirofumi, additional, Ota, Hirofumi, additional, Akamatsu, Hiroki, additional, Tamagawa, Hiroshi, additional, Shoji, Hirotaka, additional, Egi, Hiroyuki, additional, Matsubara, Hisahiro, additional, Miki, Hisanori, additional, Elfeki, Hossam, additional, Lin, Hung-Hsin, additional, Giani, Iacopo, additional, Caravaca-García, Iban, additional, Takemasa, Ichiro, additional, Angriman, Imerio, additional, Negoi, Ionut, additional, Volkova, Irina, additional, Russo, Iris, additional, Kronberger, Irmgard E, additional, Shageev, Iskander, additional, Aydin, Ishak, additional, Mora Guzmán, Ismael, additional, Novak, Ivana, additional, Giuliano, Izzo, additional, Rachmuth, Jacob, additional, Ngu, James Chi-Yong, additional, Glasbey, James, additional, Stoot, Jan, additional, Žatecky, Jan, additional, Melenhorst, Jarno, additional, Van Der Wal, J B C, additional, Leijtens, Jeroen, additional, Bogach, Jessica, additional, Elliott, Jessie, additional, De Wilt, J H W, additional, Han, Jiagang, additional, Cui, Jian, additional, Liu, Jiaqi, additional, Khan, Jim, additional, Wirawan, Jimmy Panji, additional, Zhang, Jinji, additional, Manyari, Joel Davis Osorio, additional, Doerner, Johannes, additional, Bock, Jonathan, additional, Konsten, Joop, additional, Castro, Jorge Mario, additional, Grobas, Jorge Pérez, additional, Pereira, José, additional, Juloski, Jovan, additional, Laina, Juan Luis Blas, additional, Solórzano, Juan José, additional, López, Juan Ramón Gómez, additional, Li, Jun, additional, Watanabe, Jun, additional, Kwak, Jung-Myun, additional, Hasegawa, Junichi, additional, Hiro, Junichiro, additional, Sergey, K, additional, Zhang, Kai, additional, Nagahori, Kaoru, additional, Martinez, Karla, additional, Tokuhara, Katsuji, additional, Danno, Katsuki, additional, Uehara, Kay, additional, Yoshimatsu, Kazuhiko, additional, Ehara, Kazuhisa, additional, Ueda, Kazuki, additional, Suda, Kazuyoshi, additional, Yamamoto, Kazuyuki, additional, Ishimaru, Kei, additional, Kimura, Kei, additional, Hirata, Keiji, additional, Deen, Kemal, additional, Imaizumi, Ken, additional, Yamada, Jenji, additional, Tanakura, Kenta, additional, Rida, Khaled, additional, Sugimoto, Kiichi, additional, Kotaro, Kitani, additional, Shi, Kiwisure, additional, Okabayashi, Koji, additional, Hida, Koya, additional, Kataoka, Kozo, additional, Hongo, Kumiko, additional, Xia, Kunkun, additional, Tseng, Larissa, additional, Reime, Lars, additional, Lorenzon, Laura, additional, Ruano, Laura Muiños, additional, Zhou, Lei, additional, De Nes, Lindsey, additional, Brandariz, Lorena, additional, Morini, Lorenzo, additional, Petagna, Lorenzo, additional, Ripamonti, Lorenzo, additional, Martinez, Lourdes Hernandez, additional, Pio, Luca, additional, Sacco, Luca, additional, Carvalho, Lucia, additional, Zorcolo, Luigi, additional, Pérez-Sánchez, Luis Eduardo, additional, Esparza, Luis Humberto Reyes, additional, Aguilar, Luis Tallon, additional, Garner, Madeleine, additional, Sugimoto, Maki, additional, Nagashima, Makoto, additional, Shiozawa, Manabu, additional, Simone, Manfredelli, additional, Ferrer-Marquez, Manuel, additional, Carvalho, Marcia, additional, Alifano, Marco, additional, Arganini, Marco, additional, Calussi, Marco, additional, Catarci, Marco, additional, Allaix, Marco Ettore, additional, Forlin, Marco, additional, Milone, Marco, additional, Paci, Marco, additional, Fodor, Margot, additional, Antipova, Maria, additional, Martos, Maria Beltran, additional, Giuffrida, Maria Carmela, additional, Tabernilla, María Diez, additional, Quirós, María José Alcaide, additional, Lemma, Maria, additional, Correo, Maria Luisa Reyes Diaz, additional, Małowiecka, Maria, additional, Bellomo, Maria Paola, additional, Fernandez, Maria Ramos, additional, Socias, María, additional, Rizk, Mariam, additional, Aurora, Mariani, additional, Antolinez, Mariano Alvarez, additional, Ninkovic, Marijana, additional, Giuffrida, Mario, additional, De Roos, Marnix A J, additional, Lara, Marta Cañón, additional, Agustin, Marta Climent, additional, Cuadrado, Marta, additional, Pascual, Marta, additional, Lemmerer, Martina, additional, Carlos, R, additional, Okamoto, Masa, additional, Miyo, Masaaki, additional, Inomata, Masafumi, additional, Ikenaga, Masakazu, additional, Tsujie, Masaki, additional, Yasuno, Masamichi, additional, Kotake, Masanori, additional, Sato, Masanori, additional, Yasui, Masayoshi, additional, Lavazza, Matteo, additional, Rottoli, Matteo, additional, Zuin, Matteo, additional, Zuluaga, Mauricio, additional, Cervellera, Maurizio, additional, Cesari, Maurizio, additional, Zizzo, Maurizio, additional, Garino, Mauro, additional, Ghirardi, Mauro, additional, Montuori, Mauro, additional, Podda, Mauro, additional, Santarelli, Mauro, additional, Koc, Mehmet Ali, additional, Baini, Melissa, additional, Campanelli, Michela, additional, Manigrasso, Michele, additional, Zuolo, Michele, additional, Cunha, Miguel F, additional, Misca, Mihaela, additional, Slavchev, Mihail, additional, Danilov, Mikhail, additional, Shigaev, Mikhail, additional, Martens, Milou, additional, Kobayashi, Minako, additional, Ren, Mingyang, additional, Ishizuka, Mitsuru, additional, Hassan, Mohammed Mustafa, additional, Siblini, Mohamad, additional, Sahloul, Mohamed, additional, Keramati, Mohammad Reza, additional, Karunakaran, Monish, additional, Markel, Moritz, additional, Majeed, Mudassar, additional, Younis, Muhammad Umar, additional, Akin, Muhammed Ikbal, additional, Laraibe, Munazza, additional, Derebey, Murat, additional, Kendirci, Murat, additional, Fukunaga, Mutsumi, additional, Matsubara, Nagahide, additional, Ordaz, Narce Eunice Cruz, additional, Samalavicius, Narimantas Evaldas, additional, Keeratibharat, Nattawut, additional, Angelis, Nicola, additional, Gica, Nicolae, additional, Mariani, Nicoló Maria, additional, Ramino, Nicolò, additional, Falco, Nicolò, additional, Smart, Neil, additional, De Korte, Niels, additional, Kok, Niels F M, additional, Jamieson, Nigel B, additional, Aberyasev, Nikolay, additional, Bruklich, Nikolay, additional, Ichikawa, Nobuki, additional, Miyoshi, Norikatsu, additional, De Palma, Norma, additional, Figueiredo, Nuno, additional, Torrecilla, Nuria Ortega, additional, Dybov, Oleg G, additional, Yudin, Oleg, additional, Crepin, Ollende, additional, Gomez, Oscar, additional, Sert, Ozlem Zeliha, additional, Lominchar, Pablo Lozano, additional, Menéndez, Pablo, additional, De Nardi, Paola, additional, Tejedor, Patricia, additional, Jordan, Patrick, additional, Tan, Patrick, additional, Marsanic, Patrizia, additional, Natalya, Pechnikova, additional, Baños, Pedro Parra, additional, Rebasa, Pere, additional, Neary, Peter M, additional, Tanis, Pieter, additional, Giustacchini, Piero, additional, Anoldo, Pietro, additional, Concejo, Pilar, additional, Cao, Pin, additional, Chandrasinghe, Pramodh, additional, Abeyratne, Prasad, additional, Wang, Quan, additional, Klicks, R J, additional, Riquelme, Rafael Ferrer, additional, De Luca, Raffaele, additional, Galli, Raffaele, additional, Gianesini, Raffaele, additional, Moorjani, Rajesh Gianchandani, additional, Deshpande, Rajkiran K, additional, Gorter, Ramon, additional, Ledesma, Raquel Leon, additional, Ruslan, Rategov, additional, Chhabra, Raunaq, additional, Talreja-Pelaez, Reena, additional, Suzuki, Rei, additional, Balestri, Riccardo, additional, Rosati, Riccardo, additional, Kiblawi, Rim, additional, Martins, Rita, additional, Angelico, Roberta, additional, Tutino, Roberta, additional, Persiani, Roberto, additional, Pollastri, Roberto, additional, López, Rocío González, additional, Perez, Rodrigo Oliva, additional, Hompes, Roel, additional, Lukanin, Roman, additional, Roser Termes Serra, R, additional, Brunaccino, Rossella, additional, Nakanishi, Ryota, additional, Stefan, Samuel, additional, Hernández, Sandra Paola Sánchez, additional, Di Carlo, Sara, additional, Ingallinella, Sara, additional, Domoto, Satoru, additional, Ikeda, Satoshi, additional, Mikalauskas, Saulius, additional, Kim, Seon Hahn, additional, Mantova, Serena, additional, Barbuta, Severius, additional, Li, Shaotang, additional, Yamaguchi, Shigeki, additional, Yamagishi, Shigeru, additional, Homma, Shigenori, additional, Tsujinaka, Shingo, additional, Yoshioka, Shinichi, additional, Mori, Shinichiro, additional, Tewari, Shirish, additional, Rayman, Shlomi, additional, Horiuchi, Sho, additional, Matoba, Shuichiro, additional, Morita, Shunji, additional, Yaman, Sibel, additional, Vigna, Silvia, additional, Testa, Silvio, additional, Ng, Simon, additional, Deidda, Simona, additional, Cicconi, Simone, additional, Di Maria, Simone, additional, Sibio, Simone, additional, Ersoz, Siyar, additional, Pejkova, Sofija, additional, Altarifi, Soliman, additional, He, Songbing, additional, Malakorn, Songphol, additional, Meindert, Sosef, additional, Sumikawa, Sosuke, additional, Parmar, Stavan, additional, Uranitsch, Stefan, additional, D'ugo, Stefano, additional, Giuliani, Stefano, additional, Breukink, Stéphanie, additional, Lee, Suk-Hwan, additional, Hata, Taishi, additional, Ishikawa, Takahisa, additional, Akiyoshi, Takashi, additional, Azuma, Takashi, additional, Kobatake, Takaya, additional, Fukuzaki, Takayuki, additional, Aiyama, Takeshi, additional, Yamada, Takeshi, additional, Garmanova, Tatiana, additional, Gómez-Sánchez, Tatiana, additional, Yamaguchi, Tatsuro, additional, Flores, Teresa De Jesús, additional, Usub, Teruyuki, additional, Tsuruma, Tetsuhiro, additional, Shimizu, Tetsuichiro, additional, Hristov, Tihomir Georgiev, additional, Van Loon, Ting, additional, Funakoshi, Tohru, additional, Manzia, Tommaso Maria, additional, Kiyomatsu, Tomomichi, additional, Katayama, Tomonari, additional, Kazuhito, Uemura, additional, Elmore, Ugo, additional, Grossi, Ugo, additional, Truchalev, Vadim A, additional, Rodríguez, Valentina Sosa, additional, Testa, Valentina, additional, Tonini, Valeria, additional, Celentano, Valerio, additional, Bettencourt, Vanessa, additional, Mammadov, Vasif, additional, Leyva, Verónica Alejandra Galue, additional, Mariscal, Veronica Georgina Ortega, additional, Seid, Victor Edmond, additional, Klemann, Victor, additional, Turrado-Rodriguez, Víctor, additional, Papagni, Vincenzo, additional, Vento, Vincenzo, additional, Frering, Vincent, additional, Vigorita, Vincenzo, additional, Petrove, Vitaliva V, additional, Lyadov, Vladimir, additional, Fu, Wei, additional, Mi, Wei, additional, Jeong, Woon Kyung, additional, Leclercq, Wouter K G, additional, De Sousa, Xavier, additional, Zhao, Xing, additional, Li, Xinxiang, additional, Wang, Xinxin, additional, Yang, Xuanhua, additional, Zhang, Xuelei, additional, Dong, Yan, additional, Erushevich, Yana, additional, Takii, Yasumasa, additional, Sumi, Yasuo, additional, Loli, Yeray Trujillo, additional, Yifat, Yosef Lishtzinsky, additional, Shimada, Yoshifumi, additional, Nabeya, Yoshihiro, additional, Ide, Yoshihito, additional, Wu, Yuan, additional, Tsukada, Yuichiro, additional, Miyamoto, Yuji, additional, Toiyama, Yuji, additional, Fujie, Yujiro, additional, Kaneko, Yuka, additional, Mokutani, Yukako, additional, Fujii, Yuki, additional, Kanemitsu, Yukihide, additional, Medkova, Yulia, additional, Chen, Yulong, additional, Ruiz, Yurema Gonzalez, additional, Kinugasa, Yusuke, additional, Sow, Zacaria, additional, Razzaq, Zeeshan, additional, Wang, Zejun, additional, Liu, Zheng, additional, Han, Zhenguo, additional, Tai, Zhihui, additional, Lai, Zhiyong, additional, Ng, Zi Qin, additional, and Dambrauskas, Zilvinas, additional

Published
2020
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6. Impact of asymptomatic COVID-19 patients in global surgical practice during the COVID-19 pandemic

Author

Bellato, V, primary, Konishi, T, additional, Pellino, G, additional, An, Y, additional, Piciocchi, A, additional, Sensi, B, additional, Siragusa, L, additional, Khanna, K, additional, Pirozzi, B M, additional, Franceschilli, M, additional, Campanelli, M, additional, Efetov, S, additional, Sica, G S, additional, Kefleyesus, A, additional, Hoofwijk, A G M, additional, Eldaly, Abdullah Sami, additional, Gonzalez, Abel, additional, Jawad, Adraoui, additional, Jooma, Ahmad, additional, Hafez, Ahmed Mousa, additional, Rubio, Ainhoa Valle, additional, Landaluce-Olavarria, Aitor, additional, Wu, Aiwen, additional, Nagatsu, Akihisa, additional, Inoue, Akira, additional, Kanamoto, Akira, additional, Ouchi, Akira, additional, El-Hussuna, Alaa, additional, Vazquez-Melero, Alba, additional, Wolthuis, Albert M, additional, Peral, Alberto M, additional, Lozano, Alejandra Cruz, additional, Efremov, Aleksandr, additional, Ryasantsev, Aleksandr V, additional, Di Giorgio, Alessandra, additional, Parente, Alessandro, additional, Tamburrini, Alessandro, additional, Alò, Alessio, additional, Forero-Torres, Alexander, additional, Vahrmeijer, Alexander L, additional, Varabei, Alexander, additional, Hinojosa, Siles, additional, Balkan, Ali Zeynel Abidin, additional, Frontali, Alice, additional, Oleg, Alikin, additional, Soler-Silva, Álvaro, additional, Makni, Amin, additional, André, Ana, additional, Cabrera, Ana María García, additional, Fernández, Ana María Gonzalez, additional, Minaya-Bravo, Ana M, additional, Rodríguez-Sánchez, Ana, additional, Musina, Ana-Maria, additional, Pangeni, Anang, additional, Zolotko, Anastasia, additional, Tonoyan, Andranik, additional, Balla, Andrea, additional, Belli, Andrea, additional, Cavallaro, Andrea, additional, Chierici, Andrea, additional, Divizia, Andrea, additional, Bucci, Andrea Fares, additional, Salido, Andrea Jiménez, additional, Morini, Andrea, additional, Muratore, Andrea, additional, Vignali, Andrea, additional, Chitul, Andrei, additional, Sebastian, Diaconescu Andrei, additional, Pcolkins, Andrejs, additional, Shchegolev, Andrey, additional, Hollenbeck, Andrew, additional, Wisneski, Andrew, additional, Iossa, Angelo, additional, D'Amore, Anna, additional, Hunter, Anndrew, additional, Hesketh, Anthony J, additional, La Brocca, Andrea, additional, Spinelli, Antonino, additional, Caires, Antonio, additional, D'Alessandro, Antonio, additional, Correo, Antonio Francisco Sanchís López, additional, Macrì, Antonio, additional, Navarro-Sánchez, Antonio, additional, Pronk, Apollo, additional, Akunc, Aram, additional, Mehri, Arash, additional, Pelta, Arie, additional, Papadopoulos, Aristeidis, additional, Kechagias, Aristotelis, additional, Rashid, Arshad, additional, Ramazanov, Artur, additional, Chandio, Ashfaq, additional, Kohyama, Atsushi, additional, Nishimura, Atsushi, additional, Ohkawa, Atsushi, additional, Dulskas, Audrius, additional, Jamal, Aun, additional, Mariani, Aurora, additional, Unal, Ayse Gizem, additional, Karagoz, Ayse, additional, Ozkan, Bahar Busra, additional, Salih, Barham, additional, Gülcü, Baris, additional, Pessia, Beatrice, additional, Martin-Perez, Beatriz, additional, Ielpo, Benedetto, additional, Tulelli, Berenice, additional, Yang, Bin, additional, Mhamed, Boumadani, additional, Murphy, Brenda, additional, Pirozzi, Brunella Maria, additional, Sensi, Bruno, additional, Langenhoff, Bs, additional, Belevi, Bulent, additional, Güney, Burak, additional, Ng, Caecilia, additional, Rueda, Camilo, additional, Roxburgh, Campbell S, additional, Feo, Carlo V, additional, Ferrari, Carlo, additional, Gazia, Carlo, additional, Pratesi, Carlo, additional, Ratto, Carlo, additional, Santacruz, Carlos Cerdán, additional, Arroyave, Carlos Rodolfo Martinez, additional, Macias, Carlos, additional, Fernandez, Carlota Garcia, additional, Fernandez, Carmen Cagigas, additional, Curtis-Martinez, Carolina, additional, Fortmann, Caroline, additional, Kim, Caroline, additional, Galeano, Catalina Uribe, additional, Barroso, Catarina, additional, Baldi, Caterina, additional, Foppa, Caterina, additional, Formisano, Cesare, additional, Li, Changzai, additional, Ding, Chao, additional, Wang, Chenyu, additional, Iacusso, Chiara, additional, Yang, Chongwei, additional, Pizzera, Christian, additional, Skias, Christoph, additional, Chouliras, Christos, additional, Liakos, Christos, additional, Matsuda, Chu, additional, Wu, Chun-yi, additional, Ozaslan, Cihangir, additional, Tanda, Cinzia, additional, Tommaso, Cipolat Mis, additional, Dagorno, Claire, additional, Ramos, Claudia Patricia Arellano, additional, Arcudi, Claudio, additional, Coco, Claudio, additional, Morales, Cleotilde Mateo, additional, Ali, Mujahid Zulfiqar, additional, Lozano, Coral Cózar, additional, Sala, Corrado, additional, Leo, Cosimo Alex, additional, Scarpa, Cosimo Riccardo, additional, Ferro, Cristian Varela, additional, Fernandez, Cristina Mosquera, additional, Morales-Garcia, D, additional, Nakano, Daisuke, additional, Cristian, Daniel, additional, Hechtl, Daniel, additional, Cánovas, Daniel Triguero, additional, Calabrese, Daniela, additional, Rega, Daniela, additional, Ferraro, Daniele, additional, Morezzi, Daniele, additional, Sommacale, Daniele, additional, Brogden, Danielle, additional, Miskovic, Danilo, additional, Merlini, David, additional, Pertile, Davide, additional, Coniglio, Denise, additional, Zhu, Dexiang, additional, Wu, Dianwen, additional, Coletta, Diego, additional, Rubio, Diego Ramos, additional, Sasia, Diego, additional, Fillipov, Dmitry, additional, Russiello, Domenico, additional, Dardanov, Dragomir, additional, Consten, E C J, additional, Smolskas, Edgaras, additional, Muttillo, Edoardo Maria, additional, Jones, Edward, additional, Sunami, Eiji, additional, Etienne, El-Helou, additional, Chalkiadaki, Elena, additional, Giacomelli, Elena, additional, Karbovnichaya, Elena, additional, Ruiz-Úcar, Elena, additional, Guaitoli, Eleonora, additional, Samadov, Elgun, additional, Jovine, Elio, additional, Treppiedi, Elio, additional, Vaterlini, Elisa Maria, additional, Zambaiti, Elisa, additional, Moggia, Elisabetta, additional, Coetzee, Elmi, additional, Chisari, Emanuele, additional, D'Errico, Emanuele, additional, Ciofic, Emilia, additional, Peña, Emilio, additional, Kurt, Emine, additional, Balık, Emre, additional, Gunay, Emre, additional, Sivrikoz, Emre, additional, Andolfi, Enrico, additional, Araimo, Enrico, additional, Lucci, Enrico, additional, Opocher, Enrico, additional, Pinotti, Enrico, additional, Rubino, Enrico, additional, Reyhan, Enver, additional, Mazzotta, Erica, additional, Navarro, Ernesto Barzola, additional, El-Helou, Etienne, additional, Licardie-Bolaños, Eugenio, additional, Porto, Eva Iglesias, additional, Contreras, Evelyn, additional, Boerma, Evert-Jan, additional, Cianchi, Fabio, additional, Marino, Fabio, additional, Uggeri, Fabio, additional, Han, Fanghai, additional, Calculli, Federica, additional, Falaschi, Federica, additional, Ghignone, Federico, additional, Perrone, Federico, additional, Borghi, Felice, additional, García, Felipe, additional, Agresta, Ferdinando, additional, Cananzi, Ferdinando Carlo Maria, additional, Mendoza-Moreno, Fernando, additional, Cengiz, Fevzi, additional, Almeida, Filipe Macedo, additional, Baracchi, Filippo, additional, Carannante, Filippo, additional, La Torre, Filippo, additional, Fernandes, Flavio, additional, Friedmacher, Florian, additional, Grama, Florin, additional, Carissimi, Francesca, additional, Pecchini, Francesca, additional, Bianco, Francesco, additional, Colombo, Francesco, additional, Ferrara, Francesco, additional, Litta, Francesco, additional, Carrano, Francesco Maria, additional, Martignoni, Francesco, additional, Tasselli, Francesco Menegon, additional, Milone, Francesco, additional, Pata, Francesco, additional, Sammartino, Francesco, additional, Zambianchi, Francesco, additional, Barragan, Francisco, additional, Herrero, Francisco, additional, Schlottmann, Francisco, additional, Den Boer, Frank C, additional, Pfeffer, Frank, additional, Fujita, Fumihiko, additional, Navarra, G, additional, Herrera-Almario, Gabriel, additional, Pozzo, Gabriele, additional, Capolupo, Gabriella Teresa, additional, Van Ramshorst, Gabrielle H, additional, Liscia, Gadiel, additional, Gallo, Gaetano, additional, Asawa, Ganesh, additional, Wang, Gaoxiang, additional, Raiyani, Gaurang, additional, Beets, Geerard, additional, Naval, Gemma Sugrañes, additional, Jin, Genfeng, additional, Chang, George J, additional, Saakian, George, additional, Kahane, Gerardo, additional, Borroni, Giacomo, additional, Lo Secco, Giacomo, additional, Baiocchi, Gian Luca, additional, Baronio, Gianluca, additional, Pagano, Gianluca, additional, Pattacini, Gianmaria Casoni, additional, Lisi, Giorgio, additional, Milito, Giovanni, additional, Sinibaldi, Giovanni, additional, Serrao, Giuditta, additional, Bagaglini, Giulia, additional, Sarro, Giuliano, additional, Brisinda, Giuseppe, additional, Candilio, Giuseppe, additional, Mangiameli, Giuseppe, additional, Giuliani, Giuseppe, additional, Martin-Martin, Gonzalo Pablo, additional, Bodzin, Gordon, additional, Leon, Graat, additional, Mackay, Graham, additional, Vasil, Granila, additional, Palmisano, Graziano, additional, Giovanna, Grella Maria, additional, Fernández, Guadalupe Campos, additional, Steingel, Guillermo Berrones, additional, Zhang, Guoyun, additional, Choi, Gyu Seog, additional, Chen, Haipeng, additional, Hirose, Hajime, additional, Kayano, Hajime, additional, Ulgur, Hanife Seyda, additional, Impellizzeri, Harmony, additional, Ariola, Hasani, additional, Liu, Heli, additional, Medina, Heriberto, additional, Miyauchi, Hideaki, additional, Takahashi, Hidekazu, additional, Hayashi, Hideki, additional, Ishikawa, Hideki, additional, Ishida, Hideyuki, additional, De Vries, Hilbert, additional, Ulman, Hilmican, additional, Kon, Hirofumi, additional, Ota, Hirofumi, additional, Akamatsu, Hiroki, additional, Tamagawa, Hiroshi, additional, Shoji, Hirotaka, additional, Egi, Hiroyuki, additional, Matsubara, Hisahiro, additional, Miki, Hisanori, additional, Elfeki, Hossam, additional, Lin, Hung-Hsin, additional, Giani, Iacopo, additional, Caravaca-García, Iban, additional, Takemasa, Ichiro, additional, Angriman, Imerio, additional, Negoi, Ionut, additional, Volkova, Irina, additional, Russo, Iris, additional, Kronberger, Irmgard E, additional, Shageev, Iskander, additional, Aydin, Ishak, additional, Mora Guzmán, Ismael, additional, Novak, Ivana, additional, Giuliano, Izzo, additional, Rachmuth, Jacob, additional, Ngu, James Chi-Yong, additional, Glasbey, James, additional, Stoot, Jan, additional, Žatecky, Jan, additional, Melenhorst, Jarno, additional, Van Der Wal, J B C, additional, Leijtens, Jeroen, additional, Bogach, Jessica, additional, Elliott, Jessie, additional, De Wilt, J H W, additional, Han, Jiagang, additional, Cui, Jian, additional, Liu, Jiaqi, additional, Khan, Jim, additional, Wirawan, Jimmy Panji, additional, Zhang, Jinji, additional, Manyari, Joel Davis Osorio, additional, Doerner, Johannes, additional, Bock, Jonathan, additional, Konsten, Joop, additional, Castro, Jorge Mario, additional, Grobas, Jorge Pérez, additional, Pereira, José, additional, Juloski, Jovan, additional, Laina, Juan Luis Blas, additional, Solórzano, Juan José, additional, López, Juan Ramón Gómez, additional, Li, Jun, additional, Watanabe, Jun, additional, Kwak, Jung-Myun, additional, Hasegawa, Junichi, additional, Hiro, Junichiro, additional, Sergey, K, additional, Zhang, Kai, additional, Nagahori, Kaoru, additional, Martinez, Karla, additional, Tokuhara, Katsuji, additional, Danno, Katsuki, additional, Uehara, Kay, additional, Yoshimatsu, Kazuhiko, additional, Ehara, Kazuhisa, additional, Ueda, Kazuki, additional, Suda, Kazuyoshi, additional, Yamamoto, Kazuyuki, additional, Ishimaru, Kei, additional, Kimura, Kei, additional, Hirata, Keiji, additional, Deen, Kemal, additional, Imaizumi, Ken, additional, Yamada, Jenji, additional, Tanakura, Kenta, additional, Rida, Khaled, additional, Sugimoto, Kiichi, additional, Kotaro, Kitani, additional, Shi, Kiwisure, additional, Okabayashi, Koji, additional, Hida, Koya, additional, Kataoka, Kozo, additional, Hongo, Kumiko, additional, Xia, Kunkun, additional, Tseng, Larissa, additional, Reime, Lars, additional, Lorenzon, Laura, additional, Ruano, Laura Muiños, additional, Siragusa, Leandro, additional, Zhou, Lei, additional, De Nes, Lindsey, additional, Brandariz, Lorena, additional, Morini, Lorenzo, additional, Petagna, Lorenzo, additional, Ripamonti, Lorenzo, additional, Martinez, Lourdes Hernandez, additional, Pio, Luca, additional, Sacco, Luca, additional, Carvalho, Lucia, additional, Zorcolo, Luigi, additional, Pérez-Sánchez, Luis Eduardo, additional, Esparza, Luis Humberto Reyes, additional, Aguilar, Luis Tallon, additional, Garner, Madeleine, additional, Sugimoto, Maki, additional, Nagashima, Makoto, additional, Shiozawa, Manabu, additional, Simone, Manfredelli, additional, Ferrer-Marquez, Manuel, additional, Carvalho, Marcia, additional, Alifano, Marco, additional, Arganini, Marco, additional, Calussi, Marco, additional, Catarci, Marco, additional, Allaix, Marco Ettore, additional, Forlin, Marco, additional, Milone, Marco, additional, Paci, Marco, additional, Franceschilli, Marzia, additional, Fodor, Margot, additional, Antipova, Maria, additional, Martos, Maria Beltran, additional, Giuffrida, Maria Carmela, additional, Tabernilla, María Diez, additional, Quirós, María José Alcaide, additional, Lemma, Maria, additional, Correo, Maria Luisa Reyes Diaz, additional, Małowiecka, Maria, additional, Bellomo, Maria Paola, additional, Fernandez, Maria Ramos, additional, Socias, María, additional, Rizk, Mariam, additional, Aurora, Mariani, additional, Antolinez, Mariano Alvarez, additional, Ninkovic, Marijana, additional, Giuffrida, Mario, additional, De Roos, Marnix A J, additional, Lara, Marta Cañón, additional, Agustin, Marta Climent, additional, Cuadrado, Marta, additional, Pascual, Marta, additional, Lemmerer, Martina, additional, Carlos, R, additional, Okamoto, Masa, additional, Miyo, Masaaki, additional, Inomata, Masafumi, additional, Ikenaga, Masakazu, additional, Tsujie, Masaki, additional, Yasuno, Masamichi, additional, Kotake, Masanori, additional, Sato, Masanori, additional, Yasui, Masayoshi, additional, Lavazza, Matteo, additional, Rottoli, Matteo, additional, Zuin, Matteo, additional, Zuluaga, Mauricio, additional, Cervellera, Maurizio, additional, Cesari, Maurizio, additional, Zizzo, Maurizio, additional, Garino, Mauro, additional, Ghirardi, Mauro, additional, Montuori, Mauro, additional, Podda, Mauro, additional, Santarelli, Mauro, additional, Koc, Mehmet Ali, additional, Baini, Melissa, additional, Campanelli, Michela, additional, Manigrasso, Michele, additional, Zuolo, Michele, additional, Cunha, Miguel F, additional, Misca, Mihaela, additional, Slavchev, Mihail, additional, Danilov, Mikhail, additional, Shigaev, Mikhail, additional, Martens, Milou, additional, Kobayashi, Minako, additional, Ren, Mingyang, additional, Ishizuka, Mitsuru, additional, Hassan, Mohammed Mustafa, additional, Siblini, Mohamad, additional, Sahloul, Mohamed, additional, Keramati, Mohammad Reza, additional, Karunakaran, Monish, additional, Markel, Moritz, additional, Majeed, Mudassar, additional, Younis, Muhammad Umar, additional, Akin, Muhammed Ikbal, additional, Laraibe, Munazza, additional, Derebey, Murat, additional, Kendirci, Murat, additional, Fukunaga, Mutsumi, additional, Matsubara, Nagahide, additional, Ordaz, Narce Eunice Cruz, additional, Samalavicius, Narimantas Evaldas, additional, Keeratibharat, Nattawut, additional, Angelis, Nicola, additional, Gica, Nicolae, additional, Mariani, Nicoló Maria, additional, Ramino, Nicolò, additional, Falco, Nicolò, additional, Smart, Neil, additional, De Korte, Niels, additional, Kok, Niels F M, additional, Jamieson, Nigel B, additional, Aberyasev, Nikolay, additional, Bruklich, Nikolay, additional, Ichikawa, Nobuki, additional, Miyoshi, Norikatsu, additional, De Palma, Norma, additional, Figueiredo, Nuno, additional, Torrecilla, Nuria Ortega, additional, Dybov, Oleg G, additional, Yudin, Oleg, additional, Crepin, Ollende, additional, Gomez, Oscar, additional, Sert, Ozlem Zeliha, additional, Lominchar, Pablo Lozano, additional, Menéndez, Pablo, additional, De Nardi, Paola, additional, Tejedor, Patricia, additional, Jordan, Patrick, additional, Tan, Patrick, additional, Marsanic, Patrizia, additional, Natalya, Pechnikova, additional, Baños, Pedro Parra, additional, Rebasa, Pere, additional, Neary, Peter M, additional, Tanis, Pieter, additional, Giustacchini, Piero, additional, Anoldo, Pietro, additional, Concejo, Pilar, additional, Cao, Pin, additional, Chandrasinghe, Pramodh, additional, Abeyratne, Prasad, additional, Wang, Quan, additional, Klicks, R J, additional, Riquelme, Rafael Ferrer, additional, De Luca, Raffaele, additional, Galli, Raffaele, additional, Gianesini, Raffaele, additional, Moorjani, Rajesh Gianchandani, additional, Deshpande, Rajkiran K, additional, Gorter, Ramon, additional, Ledesma, Raquel Leon, additional, Ruslan, Rategov, additional, Chhabra, Raunaq, additional, Talreja-Pelaez, Reena, additional, Suzuki, Rei, additional, Balestri, Riccardo, additional, Rosati, Riccardo, additional, Kiblawi, Rim, additional, Martins, Rita, additional, Angelico, Roberta, additional, Tutino, Roberta, additional, Persiani, Roberto, additional, Pollastri, Roberto, additional, López, Rocío González, additional, Perez, Rodrigo Oliva, additional, Hompes, Roel, additional, Lukanin, Roman, additional, Roser Termes Serra, R, additional, Brunaccino, Rossella, additional, Nakanishi, Ryota, additional, Stefan, Samuel, additional, Hernández, Sandra Paola Sánchez, additional, Di Carlo, Sara, additional, Ingallinella, Sara, additional, Domoto, Satoru, additional, Ikeda, Satoshi, additional, Mikalauskas, Saulius, additional, Kim, Seon Hahn, additional, Mantova, Serena, additional, Barbuta, Severius, additional, Li, Shaotang, additional, Yamaguchi, Shigeki, additional, Yamagishi, Shigeru, additional, Homma, Shigenori, additional, Tsujinaka, Shingo, additional, Yoshioka, Shinichi, additional, Mori, Shinichiro, additional, Tewari, Shirish, additional, Rayman, Shlomi, additional, Horiuchi, Sho, additional, Matoba, Shuichiro, additional, Morita, Shunji, additional, Yaman, Sibel, additional, Vigna, Silvia, additional, Testa, Silvio, additional, Ng, Simon, additional, Deidda, Simona, additional, Cicconi, Simone, additional, Di Maria, Simone, additional, Sibio, Simone, additional, Ersoz, Siyar, additional, Pejkova, Sofija, additional, Altarifi, Soliman, additional, He, Songbing, additional, Malakorn, Songphol, additional, Meindert, Sosef, additional, Sumikawa, Sosuke, additional, Parmar, Stavan, additional, Uranitsch, Stefan, additional, D'ugo, Stefano, additional, Giuliani, Stefano, additional, Breukink, Stéphanie, additional, Lee, Suk-Hwan, additional, Hata, Taishi, additional, Ishikawa, Takahisa, additional, Akiyoshi, Takashi, additional, Azuma, Takashi, additional, Kobatake, Takaya, additional, Fukuzaki, Takayuki, additional, Aiyama, Takeshi, additional, Yamada, Takeshi, additional, Garmanova, Tatiana, additional, Gómez-Sánchez, Tatiana, additional, Yamaguchi, Tatsuro, additional, Flores, Teresa De Jesús, additional, Usub, Teruyuki, additional, Tsuruma, Tetsuhiro, additional, Shimizu, Tetsuichiro, additional, Hristov, Tihomir Georgiev, additional, Van Loon, Ting, additional, Funakoshi, Tohru, additional, Manzia, Tommaso Maria, additional, Kiyomatsu, Tomomichi, additional, Katayama, Tomonari, additional, Kazuhito, Uemura, additional, Elmore, Ugo, additional, Grossi, Ugo, additional, Truchalev, Vadim A, additional, Rodríguez, Valentina Sosa, additional, Testa, Valentina, additional, Tonini, Valeria, additional, Celentano, Valerio, additional, Bettencourt, Vanessa, additional, Mammadov, Vasif, additional, Leyva, Verónica Alejandra Galue, additional, Mariscal, Veronica Georgina Ortega, additional, Seid, Victor Edmond, additional, Klemann, Victor, additional, Turrado-Rodriguez, Víctor, additional, Papagni, Vincenzo, additional, Vento, Vincenzo, additional, Frering, Vincent, additional, Vigorita, Vincenzo, additional, Petrove, Vitaliva V, additional, Lyadov, Vladimir, additional, Fu, Wei, additional, Mi, Wei, additional, Jeong, Woon Kyung, additional, Leclercq, Wouter K G, additional, De Sousa, Xavier, additional, Zhao, Xing, additional, Li, Xinxiang, additional, Wang, Xinxin, additional, Yang, Xuanhua, additional, Zhang, Xuelei, additional, Dong, Yan, additional, Erushevich, Yana, additional, Takii, Yasumasa, additional, Sumi, Yasuo, additional, Loli, Yeray Trujillo, additional, Yifat, Yosef Lishtzinsky, additional, Shimada, Yoshifumi, additional, Nabeya, Yoshihiro, additional, Ide, Yoshihito, additional, Wu, Yuan, additional, Tsukada, Yuichiro, additional, Miyamoto, Yuji, additional, Toiyama, Yuji, additional, Fujie, Yujiro, additional, Kaneko, Yuka, additional, Mokutani, Yukako, additional, Fujii, Yuki, additional, Kanemitsu, Yukihide, additional, Medkova, Yulia, additional, Chen, Yulong, additional, Ruiz, Yurema Gonzalez, additional, Kinugasa, Yusuke, additional, Sow, Zacaria, additional, Razzaq, Zeeshan, additional, Wang, Zejun, additional, Liu, Zheng, additional, Han, Zhenguo, additional, Tai, Zhihui, additional, Lai, Zhiyong, additional, Ng, Zi Qin, additional, and Dambrauskas, Zilvinas, additional

Published
2020
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7. A Case of a Pancreatic Neuroendocrine Tumor with Intraductal Growth and Fat Replacement in the Distal Pancreas

Author

Kazuaki Shibuya, Kazuhito Uemura, Yoshihiko Osaka, Hiroaki Takahashi, Masafumi Ohira, and Naotake Homma

Subjects
Pathology, medicine.medical_specialty, Pancreatic neuroendocrine tumor, business.industry, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Medicine, 030211 gastroenterology & hepatology, Fat replacement, business, Pancreas
Published
2017

10. Correlation between port-to-target distance and procedural difficulty in single-incision laparoscopic cholecystectomy: An observational study

Author

Masafumi Ohira, Kazuhito Uemura, Yoshio Ito, Kazuaki Shibuya, and Hiroaki Takahashi

Subjects
Male, medicine.medical_specialty, medicine.medical_treatment, Operative Time, Gallbladder Diseases, Correlation, 03 medical and health sciences, 0302 clinical medicine, Pneumoperitoneum, Bayesian multivariate linear regression, medicine, Body Size, Humans, Aged, Umbilicus, business.industry, General Medicine, Length of Stay, Middle Aged, medicine.disease, Surgery, Single incision laparoscopic, Treatment Outcome, Cholecystectomy, Laparoscopic, 030220 oncology & carcinogenesis, Operative time, 030211 gastroenterology & hepatology, Observational study, Cholecystectomy, Female, SILC, business, Tomography, X-Ray Computed
Abstract

Introduction Single-incision laparoscopic cholecystectomy (SILC) is more challenging than conventional (multiport) laparoscopic cholecystectomy (CLC) because of the increased likelihood of instrument collision and the limited surgical workspace. In SILC, procedural difficulties may increase when the port-to-target distance is long. We aimed to assess the correlation between port-to-target distance and procedural difficulty. Methods Thirty-six consecutive patients who underwent SILC at our hospital were included in this study. The umbilicus-to-Calot's triangle distance (UCD) was measured intraoperatively. The correlations between the UCD and operative time were analyzed, and for comparison, CLC cases during the same period (n = 28) were similarly analyzed. Moreover, UCD was estimated from preoperative CT (UCD-CT), and the usefulness of UCD-CT was assessed during SILC and CLC. Results Thirty-four patients successfully underwent SILC. There were positive correlations between the UCD and pneumoperitoneum time. Multivariate linear regression analysis, including BMI and height, which were previously reported to have a correlation with longer operative time in SILC, showed that UCD is an independent predictive factor for prolonged operative duration. However, BMI and height were not independent predictive factors. UCD and UCD-CT had a very strong positive correlation; therefore, UCD was estimated from CT. UCD-CT had a strong positive correlation with operative time in SILC, but not in CLC. Conclusions A longer UCD is an important predictive factor for difficult cases of SILC, but this finding is not applicable in CLC. The usefulness of UCD is specific to SILC.

Published
2018

11. [A Case of Surgical Resection of a Combined Hepatocellular and Cholangiocarcinoma with Hemobilia from Intraductal Tumor Thrombus]

Author

Kazuhito, Uemura, Hiroaki, Takahashi, Kazuhiro, Mino, Takuji, Ota, and Shunsuke, Shichi

Subjects
Cholangiocarcinoma, Male, Neoplasms, Multiple Primary, Biliary Tract Surgical Procedures, Carcinoma, Hepatocellular, Bile Duct Neoplasms, Liver Neoplasms, Hepatectomy, Humans, Neoplasm Invasiveness, Thrombosis, Aged
Abstract

We report a case of combined hepatocellular and cholangiocarcinoma with hemobilia. A 65-year-old man was admitted to our hospital because of pain in the right hypochondralrigion. Abdominal ultrasonography revealed bile duct dilatation in the lateral segment of liver and blood test findings showed elevation of the hepatobiliary enzyme, so ERC was performed and hemorrhage from the duodenal papilla was observed. In cholangiography, dilation of the left hepatic bile duct and filling defect were observed, and in the peroral cholangioscopy, a hemorrhagic papillary elevated lesion was identified in the left hepatic bile duct and diagnosed as adenocarcinoma as a result of biopsy. Left hepatectomy with caudate lobe, extrahepatic bile duct resection, lymph node dissection was performed by diagnosis of intrahepatic cholangiocarcinoma. In the resected specimen, tumor size was 16 mm, which was found in the left hepatic duct and invasived into the liver parenchyma. Histopathological examination revealed a combined hepatocellular and cholangiocarcinoma. Gemcitabin was administered as adjuvant chemotherapy for 8 months, but 1 year and 8 months after the operation, it recurred in the liver. Gemcitabin was administered, but it became PD, now it has changed to S-1 and it is SD for 2 years.

Published
2018

12. [Four Cases of Gastrointestinal Perforation Associated with Bevacizumab]

Author

Kazuhito, Uemura, Hiroaki, Takahashi, Kazuhiro, Mino, Takuji, Ota, and Shunsuke, Shichi

Subjects
Aged, 80 and over, Bevacizumab, Male, Fatal Outcome, Lung Neoplasms, Intestinal Perforation, Rectal Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Stomach Diseases, Humans, Female, Aged
Abstract

Four cases of gastrointestinal perforation associated with bevacizumab(BEV)were examined. Case 1: A 82-year-old male received FOLFIRI plus BEV for recurrent liver metastasis after rectal cancer resection. A lower esophageal perforation occurred 22 days after BEV administration and drainage was performed. Case 2: A 69-year-old female received FOLFOX4 plus BEV for unresectable rectal cancer and liver and lung metastasis. A rectal perforation occurred 6 days after BEV administration and suturing closure of the hole and colostomy was performed. Case 3: A 69-year-old female, received carboplatin(CBDCA) plus pemetrexed(PEM)plus BEV for unresectable left lung cancer and adrenal gland and lymph node metastasis. A small intestinal perforation occurred 15 days after BEV administration and ileocecal resection and primary anastomosis was performed. Case 4: A 73-year-old female received CBDCA plus PEM plus BEV for unresectable left lung carcinoma and pleural metastasis. A diverticulum of sigmoid colon perforation occurred 30 days after BEV administration and suturing closure of the hole and colostomy was performed. When we observe fever, abdominal pain, elevation of the inflammatory reaction after BEV administration, we should immediately examine gastrointestinal perforation.

Published
2018

16. A CASE OF RECTAL CANCER COMPLICATED WITH LIVER ABSCESS

Author

Takeshi Kikuchi, Yoshie Une, Yoshio Ito, Tomonari Katayama, and Kazuhito Uemura

Subjects
medicine.medical_specialty, Colorectal cancer, business.industry, Internal medicine, General Engineering, medicine, General Earth and Planetary Sciences, medicine.disease, business, Gastroenterology, General Environmental Science, Liver abscess
Abstract

肝膿瘍を契機に発見された直腸癌の1例を経験したので報告する．症例は66歳，男性．発熱，嘔吐を主訴に当院受診．血液検査にて高度の炎症所見，肝胆道系酵素の上昇とともに貧血症状がみられたため，腹部超音波および腹部CT検査を施行したところ肝外側区を中心とした多発性の低吸収域が認められた．多発性肝膿瘍と診断し，抗生剤投与および経皮経肝膿瘍ドレナージを施行．原因検索として下部消化管精査を行ったところ，直腸に1型腫瘍を認め，生検の結果は中分化型腺癌であった．これらに対し低位前方切除術および肝外側区切除術を施行．病理診断から，原発巣はtub2，ss，ly1，v0，n0，stageIIであった．また肝に転移所見はなく，肝膿瘍の原因として大腸癌からの経門脈的感染が推測された．以上より肝膿瘍の診断，治療においては，原因疾患として大腸癌の可能性も念頭においた下部消化管精査が必要であると考える．

Published
2009

17. Hepatocellular Carcinoma Extending into Right Atrium was Resected Successfully Using Cardiopulmonary Bypass

Author

Norihiko Shiiya, Takahito Nakagawa, Satoru Todo, Toshiya Kamiyama, Michiaki Matushita, Kazuhito Uemura, Yasuhiro Tani, Hirofumi Kamachi, Daisuke Fukumori, and Kazuaki Nakanishi

Subjects
medicine.medical_specialty, business.industry, Gastroenterology, medicine.disease, law.invention, medicine.anatomical_structure, law, Hepatocellular carcinoma, Internal medicine, Cardiopulmonary bypass, Cardiology, Medicine, Right atrium, Surgery, business
Abstract

右心房に腫瘍栓が達している肝細胞癌に対する手術適応は限られていたが, 手術手技の向上により, 長期予後を期待するほか, 腫瘍栓による肺梗塞や心不全による突然死を回避する目的で手術が行われている. 今回, 右心房に腫瘍栓が達した右肺全摘後の症例に対し人工心肺を併用することにより安定した血行動態の下, 腫瘍を切除しえた症例を経験した. 症例は68歳の男性で, 腫瘍は肝右葉全体を占め, 腫瘍栓が右肝静脈より右心房に達していた. 手術は肝門部処理後anterior approachで肝実質を切離し, 右肝静脈を処理すれば肝右葉を摘出できる状態にした後, 人工心肺を稼動させた. 右肝静脈を切開し腫瘍塞栓とともに切除肝を摘出した. 右心房に腫瘍栓が達しても人工心肺併用により安全に切除することができると考えられる.

Published
2006

18. Clinicopathological Features and Surgical Results of Hepatocellular Carcinoma under 2cm in Diameter

Author

Kazuaki Nakanishi, Kazuhito Uemura, Hirofumi Kamachi, Hideki Yokoo, Takahito Nakagawa, Satoru Todo, Toshiya Kamiyama, and Michiaki Matushita

Subjects
Surgical results, medicine.medical_specialty, business.industry, Hepatocellular carcinoma, Internal medicine, Gastroenterology, medicine, Clinicopathological features, Surgery, medicine.disease, business
Abstract

目的: 径2cm 以下の肝細胞癌 (以下, HCC)を臨床病理学的に検討し切除成績について検討した. 対象・方法: 1990～2003年に当科で肝切除した径2cm以下のHCC症例のうち肝不全死・他病死を除き病理検索可能であった63例. 1. 肉眼型, 最大腫瘍径による病理組織学的因子の検討. 2. 系統的切除の有無による累積生存率・無再発生存率の比較. さらに肉眼型, 最大腫瘍径による層別比較を行った. 3. 再発に有意な因子の単変量および多変量解析. 結果: 1. 肉眼型は境界不明瞭型11.1%, 単純結節型63. 5%, 単純結節周囲増殖型19.0%, 多結節癒合型6.3%.肉眼型が単純結節周囲増殖型あるいは多結節癒合型の症例や最大腫瘍径が1.5cm以上の症例では, 門脈侵襲陽性率および肝内転移陽性率は増加したが, 一方で, 高分化型の占める割合は低下した. 2. 系統的切除24例の無再発生存率は非系統的切除39例に比べ有意に良好であった. さらに, 単純結節周囲増殖型+多結節型や最大腫瘍径が1.5cm以上の症例で系統的切除を行った群は無再発生存率が有意に良好であった. 3. 再発に関し有利な因子は単変量解析では血小板数が多い, 系統的切除, 門脈侵襲陰性, 多変量解析で系統切除, 門脈侵襲陰性であった.考察: HCC は2cm以下であっても組織学的に多様であり, 単純結節周囲増殖型あるいは多結節癒合型や最大腫瘍径が1.5cm以上の症例では支配門脈領域に沿った系統的切除が有用であると思われた.

Published
2006

19. A Case of Hepatocellular Carcinoma with Long-time Survival by Successful Surgical Management of Metachronous Lung and Bilateral Adrenal Metastasis

Author

Toshiya Kamiyama, Kazuaki Nakanishi, Kazuhito Uemura, Tomoo Ito, Nozomi Minagawa, Satoru Todo, Hirofumi Kamachi, Takahito Nakagawa, and Michiaki Matsushita

Subjects
Oncology, medicine.medical_specialty, Lung, Adrenal metastasis, business.industry, Gastroenterology, medicine.disease, medicine.anatomical_structure, Internal medicine, Hepatocellular carcinoma, medicine, Surgery, Radiology, business
Abstract

肝細胞癌治療後の両側副腎, 肺への異時性転移に対し外科治療を行い, 初回手術より6年間の長期生存を得られた症例を報告する. 症例は68歳の男性で, 近医で外傷の際に肝S6/7に腫瘤を指摘され1998年2月肝細胞癌の診断で肝右葉切除術を施行した. 病理は中分化型肝細胞癌T3N0M0 stage III であった. 2000年12月左肺S9に約2cmの再発を認め, 胸腔鏡補助下左肺下葉部分切除術施行した. 2001年7月右副腎再発に対し右副腎腫瘍切除術を施行した. 2002年4月肝S4に22mmの腫瘤を認め, RFAを施行した. 2004年3月左副腎腫瘤を認め, 左副腎摘出術を施行した. 初回手術より6年の長期生存が得られ, 現在再発病巣なく健存中である. 肝細胞癌は転移再発を起こしやすい疾患であるが, 肝内病変, 肝外病変ともおのおのが治癒切除可能であれば, 積極的な手術療法により予後の改善が期待できると考えられた.

Published
2005

20. A CASE OF A CARCINOID TUMOR OF THE ACCESSORY PAPILLA VATER OF THE DUODENUM

Author

Hiroyuki Masuko, Kuniaki Okada, Shohei Osawa, Hiroyuki Ishizu, Masafumi Kondo, and Kazuhito Uemura

Subjects
Major duodenal papilla, medicine.anatomical_structure, business.industry, Duodenum, Medicine, Anatomy, business
Abstract

症例は47歳,男性.検診にて十二指腸の異常所見を指摘され当院受診.上部消化管内視鏡検査にて十二指腸副乳頭部に径15mmの中央に浅い陥凹を伴う隆起性病変を認め,生検でカルチノイドと診断された.超音波内視鏡検査では深達度smと考えられた.腹部CTでは,肝転移,十二指腸周囲のリンパ節腫脹は認めなかった.十二指腸副乳頭部カルチノイドの診断で幽門輪温存膵頭十二指腸切除術を施行した.病理組織学的所見は,十二指腸副乳頭部カルチノイド, 14×13mm,深達度sm,リンパ節14dに3個の転移を認めた.十二指腸副乳頭部カルチノイドは腫瘍径が小さくても本例のようにリンパ節転移陽性例があり,膵頭十二指腸切除のようにリンパ節郭清を伴った根治術が望ましいと考えられた.

Published
2003

21. CLINICOPATHOLOGICAL FEATURES OF PATIENTS WITH LYMPH NODE METASTASIS AT THE SPLENIC HILUM AND INDICATION OF SPLENECTOMY FOR ADVANCED GASTRIC CANCER IN THE UPPER THIRD OF THE STOMACH

Author

Hiroyuki Masuko, Kuniaki Okada, Shohei Osawa, Kazuhito Uemura, Yukifumi Kondo, and Hiroyuki Ishizu

Subjects
medicine.medical_specialty, business.industry, medicine.medical_treatment, Stomach, Splenectomy, Lymph node metastasis, Advanced gastric cancer, Gastroenterology, medicine.anatomical_structure, Splenic Hilum, Internal medicine, medicine, Clinicopathological features, Upper third, business
Abstract

胃上部進行癌の脾門リンパ節転移に関連する臨床病理学的因子を明らかにし,脾門リンパ節転移high risk群の選定と脾摘の適応について検討した.対象は1990年から1998年までに胃全摘術,脾合併切除により治癒切除が行われた胃上部進行癌99例である.脾門リンパ節転移例は16例(16.2%)に認め,リンパ節転移陰性例との間で占居部位,肉眼型,腫瘍径,深達度,総リンパ節転移個数,脈管侵襲,進行度において有意差を認めた.多変量解析における脾門リンパ節転移の危険因子は占居部位(大彎,前壁,後壁,全周),肉眼型(3型, 4型)であった.脾門リンパ節転移陽性例の5年生存率は20.8%で,陰性例と比較し有意に低率であった. 1) 占居部位が大彎,前壁,後壁,全周, 2) 肉眼型が3型, 4型の症例は脾門リンパ節転移の可能性が高く脾摘の適応であり,これ以外の症例では脾門リンパ節転移の可能性が低く,脾臓を温存できる可能性があると考えられた.

Published
2003

22. A Case Report of Pseudomyxoma Peritonei of The Ileum

Author

Tadashi Matsuhisa, Kazuhito Uemura, Kazuya Annen, Hironobu Kikuchi, Fumio Sano, Shinichi Matsuoka, and Yoshinobu Hata

Subjects
Pathology, medicine.medical_specialty, medicine.anatomical_structure, business.industry, Gastroenterology, Medicine, Pseudomyxoma peritonei, Surgery, Ileum, business, medicine.disease
Published
2000

23. Local skin flap reconstruction for abdominal wound dehiscence after abdominal surgery with a stoma: report of two cases

Author

Takeshi Kikuchi, Shigehito Yoneyama, Kazuhito Uemura, Tatsuhiko Kakisaka, Yoshie Une, Yoshio Ito, and Tomonari Katayama

Subjects
Male, medicine.medical_specialty, Rotation flap, medicine.medical_treatment, Perforation (oil well), Dehiscence, Surgical Flaps, Ileostomy, Laparotomy, Abdomen, Colostomy, Surgical Wound Dehiscence, medicine, Humans, Aged, Aged, 80 and over, business.industry, General Medicine, Fascia, Skin Transplantation, Surgery, body regions, medicine.anatomical_structure, business, Abdominal surgery
Abstract

Abdominal wound dehiscence is a serious complication of laparotomy, and fascial dehiscence in a patient with a stoma is especially difficult to manage. We describe how we performed local skin flap reconstruction for abdominal wound dehiscence in two patients with stomas. One patient underwent sigmoidectomy with a colostomy for peritonitis caused by perforated diverticulitis of the sigmoid colon. Postoperative fascial dehiscence was repaired by rhomboid flap reconstruction. The other patient underwent total gastrectomy, cholecystectomy, and splenectomy. An ileostomy was performed for digestive tract perforation, which was complicated by abdominal dehiscence with necrosis of the fascia. This was repaired by rotation flap reconstruction. The abdominal walls in both patients were repaired successfully without tension.

Published
2009

24. Safety analysis of FOLFOX as adjuvant chemotherapy for stage III colon cancer in phase II study (NORTH/HGCSG1003): Detailed analysis of peripheral sensory neuropathy

Author

Satoshi Yuki, Hiraku Fukushima, Masaya Kina, Takaya Kusumi, Yoichi M. Ito, Toshiaki Shichinohe, Fumitaka Nakamura, Masaaki Nenohi, Norihiko Takahashi, Susumu Sogabe, Yoshito Komatsu, Satoshi Hirano, Kazuteru Hatanaka, Akinobu Taketomi, Jun Konno, Kencho Miyashita, Naoya Sakamoto, Ichiro Iwanaga, Toraji Amano, and Kazuhito Uemura

Subjects
Oncology, Cancer Research, medicine.medical_specialty, business.industry, Adjuvant chemotherapy, Phases of clinical research, digestive system diseases, Stage III Colon Cancer, Regimen, FOLFOX, Internal medicine, medicine, Peripheral sensory neuropathy, business, medicine.drug
Abstract

701 Background: Oxaliplatin-containing regimen is a standard adjuvant chemotherapy for resected stage III colon cancer. Oxaliplatin-containing regimens were investigated for their efficacy in patients with resected stage III colon cancer in MOSAIC and XELOXA studies. Since these two international randomized studies were performed outside of Japan, we conducted a phase II study (NORTH/HGCSG1003) to assess the efficacy and safety of FOLFOX as adjuvant chemotherapy in Japanese patients (pts) with resected stage III colon cancer (UMIN ID: 000004590). Methods: This phase II study enrolled patients with resected stage III colon cancer. Patients received 12 biweekly cycles of FOLFOX4 or mFOLFOX6. Sample size was determined to be 243 pts. Primary endpoint was DFS. Secondary endpoints included overall survival (OS) and safety. Results: From September 2010 to March 2013, 273 pts were enrolled at 28 institutions. Safety analysis included 265 patients who received FOLFOX. Patients characteristics were as follows: median age, 65 (33-84); male/female: 131/134; PS 0/1:258/7; stage IIIA/IIIB/IIIC: 37/197/31; colon/rectosigmoid: 214/51. The most common grade 3-4 adverse events were neutrophil count decreased (48.1%), platelet count decreased (2.3%), and allergic reaction (1.5%). The incidence of peripheral sensory neuropathy (PSN) was 41.9% (grade 1), 38.1% (grade 2), and 6.4% (grade 3). PSN tended to be serious depending on the cumulative dose of oxaliplatin (table 1). Median cumulative dose of oxaliplatin at which PSN occurred were as follows: grade 1; 170 mg/m2, ≥ grade 2; 850 mg/m2, ≥ grade 3; (-). The median number of cycles of chemotherapy was 12, and the completion treatment rate was 80.4%. There was no treatment-related death. Conclusions: In Japanese patients with stage III colon cancer, FOLFOX is a well-tolerable regimen as adjuvant chemotherapy. Clinical trial information: 000004590. [Table: see text]

Published
2015

25. Clinicopathological characteristics of superficial spreading type early gastric cancer

Author

Hiroyuki Masuko, Tsunetake Hata, Masato Imai, Kuniaki Okada, Shohei Osawa, Masaya Kina, Atsushi Hino, Yukifumi Kondo, Kazuhito Uemura, Hiroyuki Ishizu, Toru Takahashi, Yasunori Nishida, Shohei Honda, and Gentaro Ishiyama

Subjects
Male, Pathology, medicine.medical_specialty, Lymphovascular invasion, medicine.medical_treatment, Gastrectomy, Stomach Neoplasms, medicine, Humans, Neoplasm Invasiveness, Pathological, Lymph node, Retrospective Studies, business.industry, Stomach, Retrospective cohort study, General Medicine, Survival Analysis, Early Gastric Cancer, Dissection, medicine.anatomical_structure, Oncology, Lymphatic Metastasis, Lymph Node Excision, Surgery, Female, Lymph Nodes, business
Abstract

Background and Objectives Superficial spreading type early gastric cancer is characterized by its atypical growth pattern and occasionally indistinct tumor margin. Because it is a rare form of early gastric cancer, the clinicopathological details are not apparent. The aim of this study was to clarify the clinicopathological features of the superficial spreading type of early gastric cancer. Methods A retrospective study was conducted in 1,062 surgically resected patients with early gastric cancer. Hospital records were compared between patients with superficial spreading type early gastric cancer and those with more common types of early gastric cancer. Results Sixty-nine patients (6.9%) had superficial spreading lesions. The male to female ratio was 1.2:1. The most frequent histological type was signet-ring cell carcinoma (32%). The distinguishing histopathological features were submucosal invasion (67%), lymphatic invasion (32%), and lymph node metastasis (30%). There were discrepancies in tumor area between surgical findings and pathological diagnosis in 24 patients (35%) with superficial spreading type. More extensive lymph node dissection was performed and all patients survived in the group with superficial spreading lesions. Conclusions The most appropriate treatment for the superficial spreading type of early gastric cancer is wide surgical resection with extensive lymph node dissection. J. Surg. Oncol. 2003;83:94–98. © 2003 Wiley-Liss, Inc.

Published
2003

26. Distant peritoneal metastasis to a mesh-plug prosthesis in a gastrointestinal cancer patient: report of a case

Author

Yukifumi Kondo, Yasunori Nishida, Masato Imai, Hiroyuki Masuko, Tsunetake Hata, Kazuhito Uemura, Atsushi Hino, Hiroyuki Ishizu, Toru Takahashi, Kuniaki Okada, Shohei Osawa, Gentaro Ishiyama, Masaya Kina, and Shohei Honda

Subjects
Male, Reoperation, medicine.medical_specialty, medicine.medical_treatment, Hernia, Inguinal, Adenocarcinoma, Prosthesis, Peritoneal Neoplasm, Fatal Outcome, Neoplasm Seeding, Gastrectomy, Biopsy, medicine, Humans, Hernia, Gastrointestinal cancer, Peritoneal Neoplasms, Aged, Gastrointestinal Neoplasms, Aged, 80 and over, medicine.diagnostic_test, business.industry, Biopsy, Needle, General Medicine, Surgical Mesh, medicine.disease, Immunohistochemistry, Surgery, Surgical mesh, business
Abstract

A case of distant metastasis to mesh-plug prosthesis in gastrointestinal cancer is presented herein. An 88-year-old man had received mesh-plug repair with high ligation for a recurrence of a right inguinal hernia. Six months later, advanced gastric cancer and advanced transverse colon cancer were detected, and therefore a distal gastrectomy and partial colectomy were performed. Two weeks after the operation, the patient complained of right groin tenderness, and the mesh-plug prosthesis was removed to control any infection. A histopathological investigation demonstrated adenocarcinoma in the plug prosthesis. The patient died of carcinomatosis peritonei 45 days after the last operation.

Published
2002

28. Distant Peritoneal Metastasis to a Mesh-Plug Prosthesis in a Gastrointestinal Cancer Patient: Report of a Case.

Author

Masato Imai, Yukifumi Kondo, Hiroyuki Masuko, Kuniaki Okada, Shohei Osawa, Hiroyuki Ishizu, Yasunori Nishida, Tsunetake Hata, Kazuhito Uemura, Masaya Kina, Shohei Honda, Gentaro Ishiyama, Toru Takahashi, and Atsushi Hino

Subjects
METASTASIS, GASTROINTESTINAL diseases, HERNIA, GASTRECTOMY
Abstract

A case of distant metastasis to mesh-plug prosthesis in gastrointestinal cancer is presented herein. An 88-year-old man had received mesh-plug repair with high ligation for a recurrence of a right inguinal hernia. Six months later, advanced gastric cancer and advanced transverse colon cancer were detected, and therefore a distal gastrectomy and partial colectomy were performed. Two weeks after the operation, the patient complained of right groin tenderness, and the mesh-plug prosthesis was removed to control any infection. A histopathological investigation demonstrated adenocarcinoma in the plug prosthesis. The patient died of carcinomatosis peritonei 45 days after the last operation. [ABSTRACT FROM AUTHOR]

Published
2003

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