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Aim: The aim of this study is to determine the prevalence of Chronic renal disease (CKD) in the patients known with gout arthritis. Method:A total of 162 patients with gout arthritis diagnosed between 2014 and 2017 were included in the study. Our work is a retrospective study. Glomerular filtration rate was calculated by Modification of Renal Disease (MDRD) method. Results: The mean age of the patients was found as 59,64 ± 14,54 (18-93). The majority of patients are male. Mean uric acid levels of the patients were found to be 9.07 mg / dL ± 1.75 (4-14.7). Among these individuals with gout arthritis, % 39,5 (64) had CKD stage 3-5, %46,9 (76) had hypertension, %18,5 (30) had diabetes mellitus, %14,2 (23) had coronary artery disease. 33.3% of the patients had CKD stage 2. Nephrolithiasis was detected in 22 of 85 ultrasound patients. The use of diuretics was detected in 36 of the patients. The consultation rate requested by the dietician was 41,4%. Conclusions: Hyperuricemia and hypertension are high in CKD. Diuretics used in the treatment of hypertension and edema may trigger gout arthritis. Similar to other studies in our study, the prevalence of CKD in gout arthritis was found high.

İnflamatuar barsak hastalıkları (IBD) Crohn hastalığı ve Ülseratif kolit olmak üzere birbirinden faklı olan iki tip kronik noninfeksiyöz gastrointestinal inflamatuar hastalıktır. IBH ekstraintestinal tutulumları arasında renal tutulum olmaktadır. IBH renal tutulumlar, glomerulonefrit, tübulointerstisyel nefrit, nefrolitiyazis ve renal amiloidozis şeklinde olmaktadır. Bu makalede nefrotik proteinüri ile başvuran 79 yaşında erkek hastada renal biyopsi ile membranöz glomerulonefrit tanısı kondu. Ayrıca yapılan kolonoskopi ile alınan barsak biyopsisinde Crohn hastalığı tanısı konan hastayı literatür eşliğinde tartışmayı amaçladık., Inflammatory bowel diseases (IBD) are two different types of chronic noninfectious gastrointestinal inflammatory diseases, namely Crohn’s disease and Ulcerative colitis. Renal involvement exists among the extraintestinal involvements of IBD. IBD renal involvements are in the form of glomerulonephritis, tubulointerstitial nephritis, nephrolithiasis, and renal amyloidosis. In this article, a 79-year-old male patient who presented with nephrotic proteinuria was diagnosed with membranous glomerulonephritis by renal biopsy. In addition, this article aims to discuss the patient who was diagnosed with Crohn’s disease in intestinal biopsy taken with colonoscopy while also referring to relative literature.

Kalıtımsal hipoürisemiye genellikle ksantinüri ve herediter renal hipoürisemi yol açmaktadır. Hipoürisemi serum ürik asit seviyesinin 2mg/dl’den düşük olması olarak tanımlanmaktadır. Ksantinüri her yaşta, nadir görülen ve otozomal resesif geçen bir hatalıktır. Ksantin ve hipoksantin, enzim veya kofaktör eksikliği sonucu ürik asite dönüşümü olmaz ve kanda birikir, ayrıca idrar ile atılımı artar. Serum ve idrarda ürik asit seviyesi çok düşük saptanmaktadır. Biz bu makalede,hipoürisemi saptanan ve ksantinüri tanısı konulan yetmiş yediyaşında kadınhasta litaratüreşliğinde tartışıldı., Xanthinuria and hereditary renal hypouricemia usually leads to hereditary hypouricemia. Hypouricemia is defined as having serum uric acid level lower than 2 ml/dl. Xanthinuria is an autosomal recessive disease that can be occasionally seen in all ages. As a result of enzyme or cofactor deficiency, xanthine and hypoxanthine do not convert to uric acid and accumulate in the blood and increase the excretion in urine. The level of uric acid is detected very low either in serum or in urine. In this study, a case of a seventy-seven-year-old female patient in which hypouricemia was detected and who had the diagnosis of xanthinuria was discussed.

Xanthinuria and hereditary renal hypouricemia usually leads to hereditary hypouricemia. Hypouricemia is defined as having serum uric acid level lower than 2 ml/dl. Xanthinuria is an autosomal recessive disease that can be occasionally seen in all ages. As a result of enzyme or cofactor deficiency, xanthine and hypoxanthine do not convert to uric acid and accumulate in the blood and increase the excretion in urine. The level of uric acid is detected very low either in serum or in urine. In this study, a case of a seventy-seven-year-old female patient in which hypouricemia was detected and who had the diagnosis of xanthinuria was discussed.