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2. The Effect of the Pre‐Transplant Disease Status on the Outcome for Recipients of T‐Cell Depleted Allogeneic Haematopoietic Stem Cell Transplants for Large B Cell Lymphomas.

Author

Marzolini, Maria A. V., Kayani, Irfan, Carpenter, Ben, Laurence, Arian, McLornan, Donal, Raj, Kavita, O'Reilly, Maeve, Roddie, Claire, Stringaris, Kate, Kottaridis, Panagiotis, Morris, Emma C., Thomson, Kirsty J., and Peggs, Karl S.

Subjects
*HEMATOPOIETIC stem cell transplantation, *HEMATOPOIETIC stem cells, *STEM cell transplantation, *POSITRON emission tomography, *TREATMENT effectiveness
Abstract

ABSTRACT Objectives Methods Results Conclusions Deauville scores (DS) from PET/CT imaging are increasingly being used to direct response‐adjusted treatment strategies in lymphoma, including large B cell lymphomas (LBCL).We aimed to investigate the outcome of allogeneic haematopoietic stem cell transplantation (alloHSCT) in LBCL and the role played by pre‐transplant disease status, as determined by DS.We performed a retrospective, observational study of adults treated with a T‐cell depleted alloHSCT for de novo DLBCL or high‐grade transformation.Sixty‐four patients received an alloHSCT. Forty‐four had acute GvHD (38 had Grade 1–2). Overall non‐relapse mortality (NRM) at 1 year was 20.31%. Patients ≥ 55 years had a higher cumulative incidence of NRM (66.67%) than those who were < 55 years (25.08%) (p = 0.00660). A 4‐year relapse risk was 22.5%. Fourteen patients had disease relapse. The 4‐year overall survival (OS) was 49.80%; median OS was 3.7 years (1.4–7.1). Patients with a pre‐alloHSCT DS of 1–2 had a higher OS than a DS of 3–5 (61.97% vs. 34.23%; p = 0.0167); this was confirmed on multivariate analysis. Younger patients (< 55 years) had a higher OS than those ≥ 55 years (60.91% vs. 18.75%; p = 0.0246).The pre‐transplant Deauville score was predictive of the clinical outcome and patients with an absence of metabolically active disease pre‐transplant had superior outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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7. PET/CT in Hodgkin’s Lymphoma: Teaching Cases

Author

Kayani, Irfan, Bomanji, Jamshed B., Series editor, Gnanasegaran, Gopinath, Series editor, Fanti, Stefano, Series editor, Macapinlac, Homer A., Series editor, Fogelman, Ignac, Series editor, and Kayani, Irfan, editor

Published
2017
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8. 18F-FDG PET/CT in Hodgkin’s Lymphoma

Author

Kayani, Irfan, Afaq, Asim, Bomanji, Jamshed B., Series editor, Gnanasegaran, Gopinath, Series editor, Fanti, Stefano, Series editor, Macapinlac, Homer A., Series editor, Fogelman, Ignac, Series editor, and Kayani, Irfan, editor

Published
2017
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11. Data from Sequential FDG-PET/CT as a Biomarker of Response to Sunitinib in Metastatic Clear Cell Renal Cancer

Author

Kayani, Irfan, primary, Avril, Norbert, primary, Bomanji, Jamshed, primary, Chowdhury, Simon, primary, Rockall, Andrea, primary, Sahdev, Anju, primary, Nathan, Paul, primary, Wilson, Peter, primary, Shamash, Jonathan, primary, Sharpe, Kevin, primary, Lim, Louise, primary, Dickson, John, primary, Ell, Peter, primary, Reynolds, Andrew, primary, and Powles, Thomas, primary

Published
2023
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12. Supplementary Figure 1 from Tumor Heterogeneity and Permeability as Measured on the CT Component of PET/CT Predict Survival in Patients with Non–Small Cell Lung Cancer

Author

Win, Thida, primary, Miles, Kenneth A., primary, Janes, Sam M., primary, Ganeshan, Balaji, primary, Shastry, Manu, primary, Endozo, Raymondo, primary, Meagher, Marie, primary, Shortman, Robert I., primary, Wan, Simon, primary, Kayani, Irfan, primary, Ell, Peter J., primary, and Groves, Ashley M., primary

Published
2023
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13. Supplementary Figure 2 from Tumor Heterogeneity and Permeability as Measured on the CT Component of PET/CT Predict Survival in Patients with Non–Small Cell Lung Cancer

Author

Win, Thida, primary, Miles, Kenneth A., primary, Janes, Sam M., primary, Ganeshan, Balaji, primary, Shastry, Manu, primary, Endozo, Raymondo, primary, Meagher, Marie, primary, Shortman, Robert I., primary, Wan, Simon, primary, Kayani, Irfan, primary, Ell, Peter J., primary, and Groves, Ashley M., primary

Published
2023
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14. Supplementary Data from Tumor Heterogeneity and Permeability as Measured on the CT Component of PET/CT Predict Survival in Patients with Non–Small Cell Lung Cancer

Author

Win, Thida, primary, Miles, Kenneth A., primary, Janes, Sam M., primary, Ganeshan, Balaji, primary, Shastry, Manu, primary, Endozo, Raymondo, primary, Meagher, Marie, primary, Shortman, Robert I., primary, Wan, Simon, primary, Kayani, Irfan, primary, Ell, Peter J., primary, and Groves, Ashley M., primary

Published
2023
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15. Supplementary Table 1 from Tumor Heterogeneity and Permeability as Measured on the CT Component of PET/CT Predict Survival in Patients with Non–Small Cell Lung Cancer

Author

Win, Thida, primary, Miles, Kenneth A., primary, Janes, Sam M., primary, Ganeshan, Balaji, primary, Shastry, Manu, primary, Endozo, Raymondo, primary, Meagher, Marie, primary, Shortman, Robert I., primary, Wan, Simon, primary, Kayani, Irfan, primary, Ell, Peter J., primary, and Groves, Ashley M., primary

Published
2023
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16. Appendix from Tumor Heterogeneity and Permeability as Measured on the CT Component of PET/CT Predict Survival in Patients with Non–Small Cell Lung Cancer

Author

Win, Thida, primary, Miles, Kenneth A., primary, Janes, Sam M., primary, Ganeshan, Balaji, primary, Shastry, Manu, primary, Endozo, Raymondo, primary, Meagher, Marie, primary, Shortman, Robert I., primary, Wan, Simon, primary, Kayani, Irfan, primary, Ell, Peter J., primary, and Groves, Ashley M., primary

Published
2023
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17. CCR Translation for This Article from Sequential FDG-PET/CT as a Biomarker of Response to Sunitinib in Metastatic Clear Cell Renal Cancer

Author

Kayani, Irfan, primary, Avril, Norbert, primary, Bomanji, Jamshed, primary, Chowdhury, Simon, primary, Rockall, Andrea, primary, Sahdev, Anju, primary, Nathan, Paul, primary, Wilson, Peter, primary, Shamash, Jonathan, primary, Sharpe, Kevin, primary, Lim, Louise, primary, Dickson, John, primary, Ell, Peter, primary, Reynolds, Andrew, primary, and Powles, Thomas, primary

Published
2023
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18. Using florbetapir positron emission tomography to explore cerebrospinal fluid cut points and gray zones in small sample sizes

Author

Weston, Philip S.J., Paterson, Ross W., Modat, Marc, Burgos, Ninon, Cardoso, Manuel J., Magdalinou, Nadia, Lehmann, Manja, Dickson, John C., Barnes, Anna, Bomanji, Jamshed B., Kayani, Irfan, Cash, David M., Ourselin, Sebastien, Toombs, Jamie, Lunn, Michael P., Mummery, Catherine J., Warren, Jason D., Rossor, Martin N., Fox, Nick C., Zetterberg, Henrik, and Schott, Jonathan M.

Published
2015
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20. CD8 Presence and Dynamics in Glofitamab-Treated Patients with Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Using the CD8-Specific PET Tracer 89Zr-Crefmirlimab Berdoxam

Author

Hutchings, Martin, primary, Loft, Annika, additional, Osborne, Wendy, additional, Petrides, George, additional, Offner, Fritz, additional, De Vriendt, Ciel, additional, Gritti, Giuseppe, additional, Boni, Roberto, additional, Townsend, William, additional, Kayani, Irfan, additional, Wilson, Ian, additional, Wang, Yanjie, additional, Jadhav, Maria, additional, Santini, Cristina, additional, Kelly, Claire, additional, Kornacker, Martin, additional, Tessier, Jean J.L., additional, Bröske, Ann-Marie E, additional, Lahr, Angelika, additional, Boehnke, Axel, additional, and Griessinger, Christoph M., additional

Published
2022
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21. Early FDG-PET response predicts CAR-T failure in large B-cell lymphoma

Author

Kuhnl, Andrea, Roddie, Claire, Kirkwood, Amy A., Menne, Tobias, Cuadrado, Maria, Marzolini, Maria A.V., Osborne, Wendy, Sanderson, Robin, O'Reilly, Maeve, Townsend, William, Benjamin, Reuben, Potter, Victoria, Patten, Piers E.M., Yallop, Deborah, Voo, Stefan, Petrides, George S., Mulholland, Nicola, and Kayani, Irfan

Published
2022
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33. Evolution of 18F-FDG PET/CT Findings in Patients After COVID-19: An Initial Investigation

Author

Thornton, Andrew, primary, Fraioli, Francesco, additional, Wan, Simon, additional, Garthwaite, Helen S., additional, Ganeshan, Balaji, additional, Shortman, Robert I., additional, Endozo, Raymond, additional, Vöö, Stefan, additional, Kayani, Irfan, additional, Neriman, Deena, additional, Menezes, Leon, additional, Bomanji, Jamshed, additional, Hilllman, Toby, additional, Heightman, Melissa, additional, Porter, Joanna C., additional, and Groves, Ashley M., additional

Published
2021
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34. Cardiac 82rubidium PET/CT: initial European experience

Author

Groves, Ashley M., Speechly-Dick, Marie-Elsya, Dickson, John C., Kayani, Irfan, Endozo, Raymondo, Blanchard, Patty, Shastry, Manu, Prvulovich, Elizabeth, Waddington, Wendy A., Ben-Haim, Simona, Bomanji, Jamshed B., McEwan, Jean R., and Ell, Peter J.

Published
2007
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