50 results on '"Kawasaki, Andrew"'
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2. Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotides
3. Solution-phase synthesis of novel linear oxyamine combinatorial libraries with antibacterial activity
4. Oligodeoxynucleotides containing 2'-O-modified adenosine: synthesis and effects on stability of DNA:RNA duplexes
5. Synthesis of 2′- O-[2-[( N, N-dialkylamino)oxy]ethyl]-modified oligonucleotides: hybridization affinity, resistance to nuclease, and protein binding characteristics
6. New Twists on Nucleic Acids
7. Synthesis, hybridization, and nuclease resistance properties of 2′-O-aminooxyethyl ( 2′-O-AOE) modified oligonucleotides
8. Discovery of a novel trans-1,4-dioxycyclohexane GPR119 agonist series
9. Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor
10. Discovery and optimization of 5-fluoro-4,6-dialkoxypyrimidine GPR119 agonists
11. Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease
12. Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P 1 agonists
13. (7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists
14. Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor
15. Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists
16. Syntheses, opioid binding affinities, and potencies of dynorphin A analogues substituted in positions 1, 6, 7, 8 and 10
17. Comparing In Vitro and In Vivo Activity of 2′-O-[2-(Methylamino)-2-oxoethyl]- and 2′-O-Methoxyethyl-Modified Antisense Oligonucleotides
18. Synthesis of 2′-O-[2-[(N,N-dialkylamino)oxy]ethyl]-modified oligonucleotides: hybridization affinity, resistance to nuclease, and protein binding characteristics
19. 2′-O-[2-(Amino)-2-oxoethyl] Oligonucleotides.
20. 2‘-O-[2-(Methylthio)ethyl]-Modified Oligonucleotide: An Analogue of 2‘-O-[2-(Methoxy)-ethyl]-Modified Oligonucleotide with Improved Protein Binding Properties and High Binding Affinity to Target RNA
21. Synthesis of 2‘-O-[2-[(N,N-Dimethylamino)oxy]ethyl] Modified Nucleosides and Oligonucleotides
22. ANTISENSE PROPERTIES OF 2′-O-DIMETHYLAMINOOXYETHYL (2′-O-DMAOE) OLIGONUCLEOTIDES
23. ChemInform Abstract: 2′‐O‐{2‐[N,N‐(Dialkyl)aminooxy]ethyl}‐Modified Antisense Oligonucleotides.
24. 2‘-O-{2-[N,N-(Dialkyl)aminooxy]ethyl}- Modified Antisense Oligonucleotides
25. ChemInform Abstract: Zwitterionic Oligonucleotides with 2′-O-[3-(N,N-Dimethylamino)propyl]-RNA Modification: Synthesis and Properties.
26. ChemInform Abstract: An Efficient Method for the Synthesis of 2′‐O‐Modified Nucleosides via Double Alkylation Using Cyclic Sulfates.
27. Zwitterionic oligonucleotides with 2′-O-[3-(N,N-dimethylamino)propyl]-RNA modification: synthesis and properties
28. An efficient method for the synthesis of 2′-O-modified nucleosides via double alkylation using cyclic sulfates
29. ChemInform Abstract: Synthesis, Hybridization, and Nuclease Resistance Properties of 2′‐O‐Aminooxyethyl Modified Oligonucleotides
30. ChemInform Abstract: Solution Phase Combinatorial Chemistry. Purine‐ and Pyrimidine‐Based Libraries with Antibacterial Activity via Solution Phase Simultaneous Addition of Functionalities
31. Synthesis, Hybridization, and Nuclease Resistance Properties of 2′-O-Aminooxyethyl Modified Oligonucleotides
32. Carbohydrate Modifications in Antisense Oligonucleotide Therapy: New Kids on the Block
33. 2′-DMAOE RNA: Emerging Oligonucleotides with Promising Antisense Properties
34. Solution Phase Combinatorial Chemistry. Purine- and Pyrimidine-Based Libraries with Antibacterial Activity via Solution Phase Simultaneous Addition of Functionalities
35. Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets
36. Design and synthesis of highly potent and selective cyclic dynorphin A analogs. 2. New analogs
37. Synthesis of 8‐amino‐4‐methylthio‐6‐methyl‐2‐(β‐D‐ribofuranosyl)‐2,6‐dihydro‐1,2,3,5,6,7‐hexaazaacenaphthylene and an unusual reductive ring‐opening of the 1,2,3,5,6,7‐hexaazaacenaphthylene ring system
38. Synthesis and cytotoxicity studies of 8-amino-6-methyl-2-.beta.-D-ribofuranosyl-1,2,3,5,6,7-hexaazaacenaphthylene (7-Aza-TCN) and the corresponding 2'-deoxy- and arabinonucleoside analogues
39. Design and synthesis of highly potent and selective cyclic dynorphin A analogs
40. The Synthesis of 8-Amino-6-N-methyl-1,2,3,5,6,7-hexaazaacenaphthylene
41. Syntheses, opioid binding affinities, and potencies of dynorphin A analogues substituted in positions 1, 6, 7, 8 and 10.
42. Zwitterionic oligonucleotides with 2′- O-[3-( N, N-dimethylamino)propyl]-RNA modification: synthesis and properties
43. Pyrrolopyrimidine nucleosides 19. A total synthesis of the nucleoside antibiotic cadeguomycin [2-amino-7-(β-d-ribofuranosyl)-pyrrolo[2,3-]pyrimidin-4-one-5-carboxylic acid]
44. An unusual reductive ring-opening of the 1,2,3,5,6,7-hexaazaacenaphthylene ring system
45. Determination of hydroxyl concentrations in prepolymers from the infrared absorption band of tetrahydrofuran-associated hydroxyl groups
46. Pyrrolopyrimidine nucleosides 19. A total synthesis of the nucleoside antibiotic cadeguomycin [2-amino-7-(β-d-ribofuranosyl)-pyrrolo[2,3- [formula omitted]]pyrimidin-4-one-5-carboxylic acid]
47. The Synthesis And Biological Activity Of Certain Hexaazaacenaphthylenes And Their Corresponding Nucleosides.
48. Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease
49. Discovery and characterization of potent and selective 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists
50. 2'-O-[2-(amino)-2-oxoethyl] oligonucleotides.
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