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7. Long‐term outcomes of endoscopic resection of superficial esophageal squamous cell carcinoma in late‐elderly patients.

Author

Matsueda, Katsunori, Kawano, Seiji, Fukui, Keisuke, Hirata, Shoichiro, Satomi, Takuya, Inoo, Shoko, Hamada, Kenta, Kono, Yoshiyasu, Iwamuro, Masaya, Kawahara, Yoshiro, and Otsuka, Motoyuki

Subjects
*OLDER patients, *ENDOSCOPIC surgery, *SQUAMOUS cell carcinoma, *AGE, *ESOPHAGEAL cancer
Abstract

Background and Aim Methods Results Conclusions As the population ages, the number of elderly patients with superficial esophageal squamous cell carcinoma (ESCC) is increasing. We aimed to clarify the indications for endoscopic resection (ER) in late‐elderly patients with ESCC in terms of life expectancy.Patients aged ≥75 years who underwent ER for ESCC at our institution from January 2005 to December 2018 were enrolled. Clinical data, including the Eastern Cooperative Oncology Group performance status, American Society of Anesthesiologists physical status (ASA‐PS), Charlson comorbidity index, and prognostic nutritional index (PNI), were collected at the time of ER. The main outcome measure was overall survival (OS).Two hundred eight consecutive patients were enrolled. The patients' median age was 78 years (range, 75–89 years). The 5‐year follow‐up rate was 88.5% (median follow‐up period, 6.6 years). The 5‐year OS rate was 79.2% (95% confidence interval [CI], 72.2–84.8), and 5‐year net survival standardized for age, sex, and calendar year was 1.04 (95% CI, 0.98–1.09). In the multivariate analysis, an ASA‐PS of 3 (hazard ratio, 2.45; 95% CI, 1.16–5.17) and PNI of <44.0 (hazard ratio, 2.73; 95% CI, 1.38–5.40) were independent prognostic factors. When neither of these factors was met, the 5‐year OS rate was 87.8% (95% CI, 80.0–92.9), and 5‐year net survival was 1.08 (95% CI, 1.02–1.14).ER for ESCC in late‐elderly patients may improve life expectancy. ER is recommended in patients with a good ASA‐PS and PNI. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Endoscopic and Histological Gastritis in University Students with Helicobacter pylori Infection

Author

Okanoue, Shotaro, primary, Sakae, Hiroyuki, additional, Yokota, Kenji, additional, Tanaka, Takehiro, additional, Obayashi, Yuka, additional, Abe, Makoto, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Kawahara, Yoshiro, additional, Yanai, Hiroyuki, additional, and Okada, Hiroyuki, additional

Published
2024
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17. MO66-2 The use of ramucirumab before nivolumab may improve survival for unresectable advanced or recurrent gastric cancer

Author

Hirata, Shoichiro, primary, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Inoo, Shoko, additional, Kuraoka, Sakiko, additional, Matsueda, Katsunori, additional, Okanoue, Shotaro, additional, Satomi, Takuya, additional, Hamada, Kenta, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, and Kawahara, Yoshiro, additional

Published
2023
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18. Optimal Bowel Preparation Method to Visualize the Distal Ileum via Small Bowel Capsule Endoscopy

Author

Kametaka, Daisuke, primary, Ito, Mamoru, additional, Kawano, Seiji, additional, Ishiyama, Shuhei, additional, Fujiwara, Akiko, additional, Nasu, Junichirou, additional, Yoshioka, Masao, additional, Shiode, Junji, additional, Yamamoto, Kazuhide, additional, Iwamuro, Masaya, additional, Kawahara, Yoshiro, additional, Okada, Hiroyuki, additional, and Otsuka, Motoyuki, additional

Published
2023
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21. Scattered Tiny Whitish Protrusions in the Stomach Are a Clue to the Diagnosis of Autoimmune Gastritis

Author

Iwamuro, Masaya, Tanaka, Takehiro, Hamada, Kenta, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Kawano, Seiji, Kawahara, Yoshiro, and Okada, Hiroyuki

Subjects
small white protrusions, mucosal lesions, esophagogastroduodenoscopy, scattered lesions, autoimmune gastritis
Abstract

Herein, we report two patients with autoimmune gastritis who had undergone multiple esophagogastroduodenoscopy procedures for 17 and 9 years, respectively, before their diagnosis. Instead, they had been diagnosed with and treated for Helicobacter pylori-associated gastritis. The correct diagnosis was made when scatterings of tiny whitish protrusions in the gastric mucosa were detected on esophagogastroduodenoscopy. Our findings suggest that scattered tiny whitish bumps may be a clue to the diagnosis of autoimmune gastritis.

Published
2023

22. Association of screening tool scores with overall survival in older patients with unresectable gastrointestinal or biliary pancreatic cancer: A retrospective study

Author

Inoo, Shoko, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Horiguchi, Shigeru, Kato, Hironari, Yamasaki, Yasushi, Hirata, Shoichiro, Kuraoka, Sakiko, Matsueda, Katsunori, Okanoue, Shotaro, Satomi, Takuya, Hamada, Kenta, Iwamuro, Masaya, Kawano, Seiji, Kawahara, Yoshiro, Okada, Hiroyuki, and Otsuka, Motoyuki

Published
2024
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24. Endoscopic features of gastric neuroendocrine carcinoma

Author

Matsueda, Katsunori, primary, Uedo, Noriya, additional, Kitamura, Masanori, additional, Shichijo, Satoki, additional, Maekawa, Akira, additional, Kanesaka, Takashi, additional, Takeuchi, Yoji, additional, Higashino, Koji, additional, Ishihara, Ryu, additional, Michida, Tomoki, additional, Kawano, Seiji, additional, and Kawahara, Yoshiro, additional

Published
2023
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25. Nationwide multicenter study on adverse events associated with a patency capsule: Additional survey of appropriate use of patency capsule study.

Author

Omori, Teppei, Ohmiya, Naoki, Watanabe, Kenji, Hirai, Fumihito, Nakamura, Masanao, Kitamura, Kazuya, Ozeki, Keiji, Oka, Shiro, Kawano, Seiji, Handa, Osamu, Kawai, Mikio, Ninomiya, Kazeo, Sagawa, Tamotsu, Wakamatsu, Takahiro, Araki, Akihiro, Koike, Yuji, Kato, Shingo, Hashimoto, Shinichi, Mannami, Tomohiko, and Nakaji, Konosuke

Subjects
CROHN'S disease, RADIO frequency identification systems, SMALL intestine, BOWEL obstructions, ABDOMINAL pain
Abstract

Background and Aim: The PillCam patency capsule (PC) without a radio frequency identification tag was released to preclude retention of the small bowel capsule endoscope (CE) in Japan in 2012. We conducted a multicenter study to determine tag‐less PC‐related adverse events (AEs). Methods: We first conducted a retrospective survey using a standardized data collection sheet for the clinical characteristics of PC‐related AEs among 1096 patients collected in a prospective survey conducted between January 2013 and May 2014 (Cohort 1). Next, we retrospectively investigated additional AEs that occurred before and after Cohort 1 within the period June 2012 and December 2014 among 1482 patients (Cohort 2). Results: Of the 2578 patients who underwent PC examinations from both cohorts, 74 AEs occurred among 61 patients (2.37%). The main AEs were residual parylene coating in 25 events (0.97%), PC‐induced small bowel obstruction, suspicious of impaction, in 23 events (0.89%), and CE retention even after patency confirmation in 10 events (0.39%). Residual parylene coating was significantly associated with Crohn's disease (P < 0.01). Small bowel obstruction was significantly associated with physicians with less than 1 year of experience handling the PC and previous history of postprandial abdominal pain (P < 0.01 and P < 0.03, respectively). CE retention was ascribed to erroneous judgment of PC localization in all cases. Conclusions: This large‐scale multicenter study provides evidence supporting the safety and efficiency of a PC to preclude CE retention. Accurate PC localization in patients without excretion and confirmation of previous history of postprandial abdominal pain before PC examinations is warranted (UMIN000010513). [ABSTRACT FROM AUTHOR]

Published
2024
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26. Clinical significance of gastrointestinal bleeding history in patients who undergo left atrial appendage closure.

Author

Kikuchi, Tatsuya, Kono, Yoshiyasu, Nakagawa, Koji, Okada, Hiroyuki, Miyamoto, Masakazu, Takaya, Yoichi, Hirata, Shoichiro, Inoo, Shoko, Kuraoka, Sakiko, Okanoue, Shotaro, Matsueda, Katsunori, Satomi, Takuya, Hamada, Kenta, Iwamuro, Masaya, Kawano, Seiji, and Kawahara, Yoshiro

Subjects
LEFT atrial appendage closure, GASTROINTESTINAL hemorrhage
Abstract

Background and Aim: Anticoagulant users with nonvalvular atrial fibrillation (NVAF) sometimes suffer from gastrointestinal bleeding (GIB) and have difficulty continuing the medication. Left atrial appendage closure (LAAC) has been developed for such situations. We aimed to clarify the clinical significance of a history of GIB in comparison to other factors in patients who had undergone LAAC. Methods: From October 2019 to September 2023, patients with NVAF who underwent LAAC at our hospital were enrolled. We investigated the percentage of patients with a history of GIB who underwent LAAC and compared the incidence of post‐LAAC bleeding in these patients compared to those with other factors. Results: A total of 45 patients were included. There were 19 patients (42%) with a history of GIB who underwent LAAC. In a Kaplan–Meier analysis, the cumulative incidence of bleeding complications after LAAC was significantly higher in patients with a history of GIB in comparison to patients with other factors. There were eight cases of post‐LAAC bleeding in total, and seven cases had GIB. Conclusions: We need to recognize that GIB is a significant complication in patients who undergo LAAC. The management of GIB by gastroenterologists is essential to the success of LAAC. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Supplementary table from A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer

Author

Kobayashi, Takashi, primary, Nishiumi, Shin, primary, Ikeda, Atsuki, primary, Yoshie, Tomoo, primary, Sakai, Aya, primary, Matsubara, Atsuki, primary, Izumi, Yoshihiro, primary, Tsumura, Hidetaka, primary, Tsuda, Masahiro, primary, Nishisaki, Hogara, primary, Hayashi, Nobuhide, primary, Kawano, Seiji, primary, Fujiwara, Yutaka, primary, Minami, Hironobu, primary, Takenawa, Tadaomi, primary, Azuma, Takeshi, primary, and Yoshida, Masaru, primary

Published
2023
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30. Supplementary Tables 1 through 7 from A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer

Author

Kobayashi, Takashi, primary, Nishiumi, Shin, primary, Ikeda, Atsuki, primary, Yoshie, Tomoo, primary, Sakai, Aya, primary, Matsubara, Atsuki, primary, Izumi, Yoshihiro, primary, Tsumura, Hidetaka, primary, Tsuda, Masahiro, primary, Nishisaki, Hogara, primary, Hayashi, Nobuhide, primary, Kawano, Seiji, primary, Fujiwara, Yutaka, primary, Minami, Hironobu, primary, Takenawa, Tadaomi, primary, Azuma, Takeshi, primary, and Yoshida, Masaru, primary

Published
2023
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31. Supplementary figure from A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer

Author

Kobayashi, Takashi, primary, Nishiumi, Shin, primary, Ikeda, Atsuki, primary, Yoshie, Tomoo, primary, Sakai, Aya, primary, Matsubara, Atsuki, primary, Izumi, Yoshihiro, primary, Tsumura, Hidetaka, primary, Tsuda, Masahiro, primary, Nishisaki, Hogara, primary, Hayashi, Nobuhide, primary, Kawano, Seiji, primary, Fujiwara, Yutaka, primary, Minami, Hironobu, primary, Takenawa, Tadaomi, primary, Azuma, Takeshi, primary, and Yoshida, Masaru, primary

Published
2023
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32. Supplementary Figure 1 from A Novel Serum Metabolomics-Based Diagnostic Approach to Pancreatic Cancer

Author

Kobayashi, Takashi, primary, Nishiumi, Shin, primary, Ikeda, Atsuki, primary, Yoshie, Tomoo, primary, Sakai, Aya, primary, Matsubara, Atsuki, primary, Izumi, Yoshihiro, primary, Tsumura, Hidetaka, primary, Tsuda, Masahiro, primary, Nishisaki, Hogara, primary, Hayashi, Nobuhide, primary, Kawano, Seiji, primary, Fujiwara, Yutaka, primary, Minami, Hironobu, primary, Takenawa, Tadaomi, primary, Azuma, Takeshi, primary, and Yoshida, Masaru, primary

Published
2023
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33. Improved Object Detection Artificial Intelligence Using the Revised RetinaNet Model for the Automatic Detection of Ulcerations, Vascular Lesions, and Tumors in Wireless Capsule Endoscopy

Author

Nakada, Ayako, primary, Niikura, Ryota, additional, Otani, Keita, additional, Kurose, Yusuke, additional, Hayashi, Yoshito, additional, Kitamura, Kazuya, additional, Nakanishi, Hiroyoshi, additional, Kawano, Seiji, additional, Honda, Testuya, additional, Hasatani, Kenkei, additional, Sumiyoshi, Tetsuya, additional, Nishida, Tsutomu, additional, Yamada, Atsuo, additional, Aoki, Tomonori, additional, Harada, Tatsuya, additional, Kawai, Takashi, additional, and Fujishiro, Mitsuhiro, additional

Published
2023
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34. Review of oral and pharyngolaryngeal benign lesions detected during esophagogastroduodenoscopy

Author

Iwamuro, Masaya, Hamada, Kenta, Kawano, Seiji, Kawahara, Yoshiro, Otsuka, Motoyuki, Iwamuro, Masaya, Hamada, Kenta, Kawano, Seiji, Kawahara, Yoshiro, and Otsuka, Motoyuki

Abstract

Recent advancements in endoscopy equipment have facilitated endoscopists’ detection of neoplasms in the oral cavity and pharyngolaryngeal regions. In particular, image-enhanced endoscopy using narrow band imaging or blue laser imaging play an integral role in the endoscopic diagnosis of oral and pharyngolaryngeal cancers. Despite these advancements, limited studies have focused on benign lesions that can be observed during esophagogastroduodenoscopy in the oral and pharyngolaryngeal regions. Therefore, this mini-review aimed to provide essential information on such benign lesions, along with representative endoscopic images of dental caries, cleft palate, palatal torus, bifid uvula, compression by cervical osteophytes, tonsil hyperplasia, black hairy tongue, oral candidiasis, oral and pharyngolaryngeal ulcers, pharyngeal melanosis, oral tattoos associated with dental alloys, retention cysts, papilloma, radiation-induced changes, skin flaps, vocal cord paresis, and vocal fold leukoplakia. Whilst it is imperative to seek consultation from otolaryngologists or dentists in instances where the diagnosis cannot be definitively ascertained by endoscopists, the merits of attaining foundational expertise pertaining to oral and pharyngolaryngeal lesions are unequivocal. This article will be a valuable resource for endoscopists seeking to enhance their understanding of oral and pharyngolaryngeal lesions.

Published
2023

37. Analysis of Factors Affecting SOC during Residency Training

Author

Kimura, Maki and Kawano, Seiji

Abstract

大学医学部を卒業し、医師国家試験に合格した者が行う初期臨床研修において、初期臨床研修医は様々なストレスに直面する。SOC（Sense of Coherence：首尾一貫感覚）は、ストレス対処や健康保持能力に有用と言われている。また、不利な状況に直面しても、正常な平衡状態を維持できる特性や能力として、レジリエンスという概念も提唱されている。レジリエンス尺度として、精神的回復力尺度（ARS:Adolescent Resilience Scale）が挙げられる。初期臨床研修におけるSOC の推移とその関連要因について検討するため、初期臨床研修医80 名を対象として、新規採用時および研修1 年経過時の計2 回、日本語版SOC-13 を用いた自記式質問紙調査、および、ARS について調査を行った。一般コース（2 年一貫の大学病院研修）で研修1 年後のSOC の有意味感が減少し、同時期のたすきがけコース（1 年目：連携病院研修 2 年目：大学病院研修）に比較して有意差を認めた。たすきがけコース研修1 年後の把握可能感・処理可能感が上昇した。研修前ARS 総点と研修前SOC 総点に弱い相関関係を認め、ARS 総点が低い研修医ほど、SOC も同様に低い傾向を認めた。初期臨床研修中のみならず、その後の経時的な推移の解析の有用性が示唆されたためここに報告する。

Published
2022

38. Degree of pharyngeal deformation caused by pharyngeal endoscopic submucosal dissection is associated with the incidence of aspiration pneumonia

Author

Abe, Makoto, additional, Kawahara, Yoshiro, additional, Obayashi, Yuka, additional, Baba, Yuki, additional, Hamada, Kenta, additional, Sakae, Hiroyuki, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitu, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Makino, Takuma, additional, Noda, Yohei, additional, Marunaka, Hidenori, additional, and Okada, Hiroyuki, additional

Published
2023
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45. Multicenter Prospective Study on the Safety of Upper Gastrointestinal Endoscopic Procedures in Antithrombotic Drug Users

Author

Kono, Yoshiyasu, Matsubara, Minoru, Toyokawa, Tatsuya, Takenaka, Ryuta, Suzuki, Seiyu, Nasu, Junichirou, Yoshioka, Masao, Nakagawa, Masahiro, Mizuno, Motowo, Sakae, Hiroyuki, Abe, Makoto, Gotoda, Tatsuhiro, Miura, Ko, Kanzaki, Hiromitsu, Iwamuro, Masaya, Hori, Keisuke, Tsuzuki, Takao, Kita, Masahide, Kawano, Seiji, Kawahara, Yoshiro, and Okada, Hiroyuki

Published
2017
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47. Postoperative Bleeding Risk after Gastric Endoscopic Submucosal Dissection in Patients Receiving a P2Y12 Receptor Antagonist

Author

Hirai, Ryosuke, primary, Kawano, Seiji, additional, Inoo, Shoko, additional, Kuraoka, Sakiko, additional, Okanoue, Shotaro, additional, Satomi, Takuya, additional, Hamada, Kenta, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Iwamuro, Masaya, additional, Kawahara, Yoshiro, additional, and Okada, Hiroyuki, additional

Published
2022
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