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175 results on '"Kawamura, Tetsuji"'

1. Refractory phenotype of Aspergillus-sensitized asthma with bronchiectasis and allergic bronchopulmonary aspergillosis

Author

Ikeda, Miho, Okamura, Kayoko, Ohnishi, Hisashi, Terada-Hirashima, Junko, Hojo, Masayuki, Isogai, Sumito, Imaizumi, Kazuyoshi, Horiguchi, Takahiro, Hirano, Ryosuke, Fujita, Masaki, Toyoshima, Mikio, Fujisawa, Tomoyuki, Suda, Takafumi, Takaki, Yoichi, Higaki, Naoko, Miyamoto, Shintaro, Nakashima, Taku, Iwamoto, Hiroshi, Hattori, Noboru, Mikami, Koji, Minami, Toshiyuki, Takahashi, Ryo, Kijima, Takashi, Tobino, Kazunori, Hoshino, Makoto, Imokawa, Shiro, Tsuji, Taisuke, Hiraoka, Noriya, Ikeue, Tatsuyoshi, Sugita, Takakazu, Kunichika, Naomi, Tomari, Shinya, Okochi, Yasumi, Mato, Naoko, Hagiwara, Koichi, Dobashi, Kunio, Taooka, Yasuyuki, Harada, Norihiro, Machida, Kentaro, Inoue, Hiromasa, Tanosaki, Takae, Masaki, Katsunori, Fukunaga, Koichi, Sano, Akiko, Iwanaga, Takashi, Higashimoto, Yuji, Tohda, Yuji, Matsumoto, Masataka, Takatsuki, Kiyonobu, Nagata, Kazuma, Tachikawa, Ryo, Tomii, Keisuke, Kaneko, Masahiro, Tomioka, Hiromi, Nagano, Tatsuya, Nishimura, Yoshihiro, Yamane, Mayuka, Yokoyama, Akihito, Yoshida, Chieko, Sakagami, Takuro, Seto, Yurie, Kaneko, Yoshiko, Takayama, Koichi, Hayashi, Yusuke, Terada, Satoru, Nishi, Kenta, Sunadome, Hironobu, Nagasaki, Tadao, Oguma, Tsuyoshi, Tanabe, Naoya, Hirai, Toyohiro, Nomura, Natsuko, Matsumoto, Hisako, Tajiri, Tomoko, Niimi, Akio, Nakamura, Saya, Wakahara, Keiko, Hashimoto, Naozumi, Ito, Takefumi, Nakano, Takako F., Yamashita, Takafumi, Takata, Shohei, Seri, Yoshihiro, Mizumori, Yasuyuki, Tsukamoto, Hiroaki, Kagami, Ryogo, Nakahara, Yasuharu, Kawamura, Tetsuji, Ishii, Yukio, Kita, Toshiyuki, Hidaka, Kouko, Kadowaki, Toru, Minakuchi, Masayoshi, Tsuboi, Tomomasa, Tamaki, Shinji, Matsuki, Takanori, Kida, Hiroshi, Miki, Mari, Tomita, Katsuyuki, Abe, Takashi, Shindoh, Joe, Taniguchi, Akihiko, Miyahara, Nobuaki, Azuma, Masato, Kataoka, Mikio, Matsuno, Osamu, Ogawa, Haruhiko, Matsumoto, Takeshi, Aihara, Kensaku, Nakagome, Kazuyuki, Nagata, Makoto, Miyajima, Satsuki, Hashimoto, Kentaro, Shiota, Tetsuhiro, Yamaguchi, Masafumi, Nakano, Yasutaka, Otsuka, Kojiro, Yasuo, Masanori, Hanaoka, Masayuki, Yamada, Takashi, Shirai, Toshihiro, Iwasaki, Yoshinobu, Mineshita, Masamichi, Tsuburai, Takahiro, Komase, Yuko, Koh, Hidefumi, Hasegawa, Koichi, Kita, Hideo, Nagase, Hiroyuki, Murakami, Koji, Sugiura, Hisatoshi, Ichinose, Masakazu, Kutsuzawa, Tomoko, Tanaka, Jun, Asano, Koichiro, Kono, Yuta, Abe, Shinji, Nakamura, Morio, Orimo, Mami, Tagaya, Etsuko, Kondo, Mitsuko, Matsuda, Toshiaki, Kimura, Tomoki, Harada, Tomoya, Yamasaki, Akira, Taniguchi, Hirokazu, Iijima, Hiroaki, Kawabata, Hiroki, Yatera, Kazuhiro, Masuko, Hironori, Morishima, Yuko, Hizawa, Nobuyuki, Nakanishi, Masanori, Yamamoto, Nobuyuki, Inoue, Sumito, Hamada, Kazuki, Yamaji, Yoshikazu, Hirano, Tsunahiko, Matsunaga, Kazuto, and Sato, Yoko

Published
2025
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4. Nationwide survey of refractory asthma with bronchiectasis by inflammatory subtypes

Author

Nomura, Natsuko, Matsumoto, Hisako, Yokoyama, Akihito, Nishimura, Yoshihiro, Asano, Koichiro, Niimi, Akio, Tohda, Yuji, Harada, Norihiro, Nagase, Hiroyuki, Nagata, Makoto, Inoue, Hiromasa, Kondo, Mitsuko, Horiguchi, Takahiko, Miyahara, Nobuaki, Hizawa, Nobuyuki, Hojo, Masayuki, Hattori, Noboru, Hashimoto, Naozumi, Yamasaki, Akira, Kadowaki, Toru, Kimura, Tomoki, Miki, Mari, Taniguchi, Hirokazu, Toyoshima, Mikio, Kawamura, Tetsuji, Matsuno, Osamu, Sato, Yoko, Sunadome, Hironobu, Nagasaki, Tadao, Oguma, Tsuyoshi, and Hirai, Toyohiro

Published
2022
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6. Cutaneous T-cell-attracting chemokine as a novel biomarker for predicting prognosis of idiopathic pulmonary fibrosis: a prospective observational study

Author

Niwamoto, Takafumi, Handa, Tomohiro, Murase, Yuko, Nakatsuka, Yoshinari, Tanizawa, Kiminobu, Taguchi, Yoshio, Tomioka, Hiromi, Tomii, Keisuke, Kita, Hideo, Uyama, Michihiro, Tsuchiya, Michiko, Emura, Masahito, Kawamura, Tetsuji, Arai, Naoki, Arita, Machiko, Uno, Kazuko, Yoshizawa, Akihiko, Uozumi, Ryuji, Yamaguchi, Izumi, Matsuda, Fumihiko, Chin, Kazuo, and Hirai, Toyohiro

Published
2021
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10. Pneumocystis jirovecii pneumonia mortality risk associated with preceding long-term steroid use for the underlying disease: a multicenter, retrospective cohort study.

Author

Miyake, Kohei, primary, Senoo, Satoru, additional, Shiiba, Ritsuya, additional, Itano, Junko, additional, Kimura, Goro, additional, Kawahara, Tatsuyuki, additional, Tamura, Tomoki, additional, Kudo, Kenichiro, additional, Kawamura, Tetsuji, additional, Nakahara, Yasuharu, additional, Higo, Hisao, additional, Himeji, Daisuke, additional, Takigawa, Nagio, additional, and Miyahara, Nobuaki, additional

Published
2023
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11. Pneumocystis jirovecii pneumonia mortality risk associated with preceding long-term steroid use for the underlying disease: A multicenter, retrospective cohort study.

Author

Miyake, Kohei, Senoo, Satoru, Shiiba, Ritsuya, Itano, Junko, Kimura, Goro, Kawahara, Tatsuyuki, Tamura, Tomoki, Kudo, Kenichiro, Kawamura, Tetsuji, Nakahara, Yasuharu, Higo, Hisao, Himeji, Daisuke, Takigawa, Nagio, and Miyahara, Nobuaki

Subjects
PNEUMOCYSTIS pneumonia, PNEUMONIA-related mortality, STEROID drugs, COHORT analysis, MORTALITY risk factors
Abstract

Objective: Long-term steroid use increases the risk of developing Pneumocystis pneumonia (PcP), but there are limited reports on the relation of long-term steroid and PcP mortality. Methods: Retrospective multicenter study to identify risk factors for PcP mortality, including average steroid dose before the first visit for PcP in non-human immunodeficiency virus (HIV)-PcP patients. We generated receiver operating characteristic (ROC) curves for 90-day all-cause mortality and the mean daily steroid dose per unit body weight in the preceding 10 to 90 days in 10-day increments. Patients were dichotomized by 90-day mortality and propensity score-based stabilized inverse probability of treatment weighting (IPTW) adjusted covariates of age, sex, and underlying disease. Multivariate analysis with logistic regression assessed whether long-term corticosteroid use affected outcome. Results: Of 133 patients with non-HIV-PcP, 37 died within 90 days of initial diagnosis. The area under the ROC curve for 1–40 days was highest, and the optimal cutoff point of median adjunctive corticosteroid dosage was 0.34 mg/kg/day. Past steroid dose, underlying interstitial lung disease and emphysema, lower serum albumin and lower lymphocyte count, higher lactate dehydrogenase, use of therapeutic pentamidine and therapeutic high-dose steroids were all significantly associated with mortality. Underlying autoimmune disease, past immunosuppressant use, and a longer time from onset to start of treatment, were associated lower mortality. Logistic regression analysis after adjusting for age, sex, and underlying disease with IPTW revealed that steroid dose 1–40 days before the first visit for PcP (per 0.1 mg/kg/day increment, odds ratio 1.36 [95% confidence interval = 1.16–1.66], P<0.001), low lymphocyte counts, and high lactate dehydrogenase revel were independent mortality risk factor, while respiratory failure, early steroid, and sulfamethoxazole/trimethoprim for PcP treatment did not. Conclusion: A steroid dose before PcP onset was strongly associated with 90-day mortality in non-HIV-PcP patients, emphasizing the importance of appropriate prophylaxis especially in this population. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Additional file 1 of Nationwide survey of refractory asthma with bronchiectasis by inflammatory subtypes

Author

Nomura, Natsuko, Matsumoto, Hisako, Yokoyama, Akihito, Nishimura, Yoshihiro, Asano, Koichiro, Niimi, Akio, Tohda, Yuji, Harada, Norihiro, Nagase, Hiroyuki, Nagata, Makoto, Inoue, Hiromasa, Kondo, Mitsuko, Horiguchi, Takahiko, Miyahara, Nobuaki, Hizawa, Nobuyuki, Hojo, Masayuki, Hattori, Noboru, Hashimoto, Naozumi, Yamasaki, Akira, Kadowaki, Toru, Kimura, Tomoki, Miki, Mari, Taniguchi, Hirokazu, Toyoshima, Mikio, Kawamura, Tetsuji, Matsuno, Osamu, Sato, Yoko, Sunadome, Hironobu, Nagasaki, Tadao, Oguma, Tsuyoshi, and Hirai, Toyohiro

Abstract

Additional file 1: Figure S1. Transition patterns of inflammatory types in cases who were not receiving anti-type 2 biologics or regular oral corticosteroids (≥5 mg/day) and were followed up for ≥2 years (n = 51). Red flow indicates former type 2-high group (n = 15), yellow flow indicates former type 2-intermediate group (n = 21) and blue flow indicates former type 2-low inflammatory group (n = 15). Figure S2. Receiver operating characteristic (ROC) curve for current levels of exhaled nitric oxide (FeNO) that reflected the presence of A) gram-negative bacteria (GNB) and B) P. aeruginosa in the sputum. Detection rate of C) GNB and D) P. aeruginosa in the sputum according to the FeNO levels, as determined by ROC curve analysis. Figure S3. A) Modified Reiff score and B) number of lobes affected by bronchiolitis in low and high exhaled nitric oxide (FeNO) groups. Recent indices were analysed. Boxes and bars indicate upper, lower, and median quartiles. Figure S4. Patterns of cases with exacerbations requiring systemic corticosteroids (SCS) and antibiotics and bronchopneumonia, according to the transition patterns of inflammatory groups (p = 0.056 among the three groups). Red bar indicates cases with three types of episodes in the last 2 years, i.e., exacerbations requiring SCS and antibiotics, and bronchopneumonia; orange bar, exacerbations requiring SCS and antibiotics; yellow bar, exacerbations requiring SCS only: blue bar, bronchopneumonia and exacerbations requiring antibiotics; purple bar, bronchopneumonia only; green bar, exacerbations requiring antibiotics only. Complete answers were missing from two cases in the low-to-low group, four in the high’-to-low group, and eight in the high’-to-high’ group. Ratios of cases with exacerbation requiring antibiotics (p = 0.01) and bronchopneumonia (p = 0.006) were significantly different among the three groups. Figure S5. Changes in terms of A) inhaled corticosteroid (ICS) doses (equivalent to fluticasone propionate), B) modified Reiff scores, C) number of lobes affected by bronchiolitis, D) detection rates of gram-negative bacteria (GNB) in sputum and E) detection rates of P. aeruginosa in sputum over time. Blue line indicates low-to-low group, yellow line indicates high’-to-low group and pink line indicates high’-to-high’ group. The numbers of cases in the low-to-low, high’-to-low, and high’-to-high’ groups were 17/19/35 for A), 19/21/40 for B); 15/21/34 for C); 17/15/32 for D) and 17/15/32 for E). Figure S6. Transition patterns of airway lesions, i.e., bronchiectasis, bronchiolitis, and both, in cases followed for 2 years or more. A) In all cases regardless of type 2 inflammation level, purple flow indicates former bronchiectasis only (n = 17); orange flow, former bronchiolitis only (n = 36); green flow, bronchiectasis and bronchiolitis in the past (n = 63); B) current type 2-high group (n = 14), C) current type 2-intermediate group (n = 17) and D) current type 2-low group (n = 41). Figure S7. Trajectories of blood eosinophil counts of patients with ≥3 data points allocated to A) high’-to-high’, B) high’-to-low and C) low-to-low groups. Patients represented by grey and brown lines in A), who received oral corticosteroids or anti-type 2 biologics, or both, had elevated exhaled nitric oxide (>100 ppb), and they were allocated to the high’-to-high group. Table S1. Characteristics of patients who were and were not stratified. Table S2. Features related to asthma and comorbidities according to the current inflammatory types. Table S3. Most effective treatment evaluated by attending physicians. Table S4. Features related to asthma according to the transition patterns of inflammatory types.

Published
2023
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17. The Global Financial and Economic Crisis and Marxian Crisis Theory : From the Perspective of the Stages Theory Originated by the Uno School

Author

KAWAMURA, Tetsuji

Abstract

The global financial and economic crisis, aggravated in the fall of 2008 in particular, has been described as a “once in a hundred years” crisis (Greenspan [2008]) or one of the “worst since the Great Depression” (Geithner [2008]). It is appropriate to analyze it as a “structural crisis” similar to the 1930s Great Depression that led to the total disintegration of the world capitalist economy. In this sense, it should be elucidated as a “global crisis” of the “global capitalist system” brought about by the structural characteristics inherent to the specific capital accumulation structure and the mechanism of the current phase of modern capitalism. The economic crisis in real world cannot be reduced to a pure theoretical model of the crisis theory. It must be comprehensively elucidated as a “global crisis,” including its historical dimension, in light of the Stages Theory originated by the Japanese Uno School, although it should be reformulated according to the two stages of the “Pax Britannica Stage” and the “Pax Americana Stage.” In accordance with this reformulation, the current global capitalism is defined as a capitalism in the “transfiguring phase” of the “Pax Americana Stage,” including significant processes of transition toward a new stage of capitalist development. The global financial and economic crisis in the late 2000s was the global “Great Crisis” that was brought about by causes deep-rooted in the capital accumulation system specific to the current phase of capitalist development.

Published
2021

18. Precut technique using an injection needle: A retrospective study on a new ancillary procedure for pleural biopsy

Author

Mizumori, Yasuyuki, primary, Hirano, Katsuya, additional, Hirata, Nobuya, additional, Hiraoka, Ryota, additional, Takahashi, Sayaka, additional, Kominami, Ryota, additional, Miyake, Kohei, additional, Takenouchi, Masaki, additional, Kato, Tomohiro, additional, Kume, Sachie, additional, Higashino, Sachiko, additional, Nakahara, Yasuharu, additional, and Kawamura, Tetsuji, additional

Published
2022
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21. Additional file 1 of Cutaneous T-cell-attracting chemokine as a novel biomarker for predicting prognosis of idiopathic pulmonary fibrosis: a prospective observational study

Author

Niwamoto, Takafumi, Handa, Tomohiro, Murase, Yuko, Nakatsuka, Yoshinari, Tanizawa, Kiminobu, Taguchi, Yoshio, Tomioka, Hiromi, Tomii, Keisuke, Kita, Hideo, Uyama, Michihiro, Tsuchiya, Michiko, Emura, Masahito, Kawamura, Tetsuji, Arai, Naoki, Arita, Machiko, Uno, Kazuko, Yoshizawa, Akihiko, Uozumi, Ryuji, Yamaguchi, Izumi, Matsuda, Fumihiko, Chin, Kazuo, and Hirai, Toyohiro

Subjects
respiratory system, respiratory tract diseases
Abstract

Additional file 1: Table S1. Results of 48-plex measurement in the sera of IPF patients (discovery cohort) and controls and the bronchoalveolar lavage fluid of IPF patients. Measurements (median and IQR) of 48 cytokines in the discovery cohort sera (n = 100) and the control group sera (n = 32), p-values for between-group comparisons, and the measurements of BALF in the discovery cohort (n = 30).

Published
2021
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22. Prognostic prediction for newly diagnosed patients with idiopathic interstitial pneumonia: JIPS Registry (NEJ030)

Author

Okuda, Ryo, Ogura, Takashi, Hisata, Shu, Baba, Tomohisa, Kondoh, Yasuhiro, Suda, Takafumi, Johkoh, Takeshi, Iwasawa, Tae, Tomioka, Hiromi, Bando, Masashi, Azuma, Arata, Inoue, Yoshikazu, Ishikawa, Nobuhisa, Arai, Naoki, Takihara, Takahisa, Hamaguchi, Megumi, Arai, Toru, Nakamura, Yutaro, Miyamoto, Atsushi, Tomii, Keisuke, Miyazaki, Yasunari, Chiba, Hirofumi, Ishii, Haruyuki, Hamada, Naoki, Terasaki, Yasuhiro, Fukuoka, Junya, Sakai, Fumikazu, Egashira, Ryoko, Fujimoto, Kiminori, Sumikawa, Hiromitsu, Suzuki, Takuji, Sakamoto, Susumu, Nishioka, Yasuhiko, Hattori, Noboru, Hashimoto, Naozumi, Morita, Satoshi, Ichihara, Nao, Miyata, Hiroaki, Hagiwara, Koichi, Kobayashi, Kunihiko, Nukiwa, Toshihiro, Arita, JIPS registry investigators: Machiko, Ebina, Masahito, Fukushima, Yasutsugu, Funaki, Yoshihiro, Gon, Yasuhiro, Handa, Tomohiro, Hara, Hiromichi, Hashimoto, Dai, Hashimoto, Seishu, Ichikado, Kazuya, Ichiyasu, Hidenori, Imaizumi, Kazuyoshi, Inomata, Minoru, Ishimoto, Hiroshi, Ito, Hiroyuki, Iwabuchi, Katsuyoshi, Kagajo, Michiko, Kato, Motoyasu, Katsuta, Tomoya, Kawamura, Tetsuji, Kimura, Masahiro, Kimura, Yuichiro, Kishaba, Tomoo, Koga, Yasuhiko, Kohashi, Yasuo, Kono, Chiyoko, Morikawa, Kei, Nakagawa, Hiroaki, Narumoto, Osamu, Ohkubo, Hirotsugu, Okamoto, Masaki, Oyamada, Yoshitaka, Sakamoto, Keita, Sasaki, Tomoya, Sato, Shintaro, Shikama, Yusuke, Shimizu, Yasuo, Suzuki, Shinko, Taima, Kageaki, Takamatsu, Kazufumi, Tanigawa, Motoaki, Tanino, Yoshinori, Nishiyama, Osamu, Toyoshima, Mikio, Tsuruno, Kosuke, Uchida, Akifumi, Urushiyama, Hirokazu, Usui, Kazuhiro, Wasamoto, Satoshi, Waseda, Yuko, Watanabe, Satoshi, Yamamoto, Hiroshi, Yatera, Kazuhiro, and Yokomura, Koshi

Abstract

Prognostic factors in patients with newly diagnosed idiopathic interstitial pneumonia (IIP) have rarely been analyzed using prospective data. This study investigated prognostic factors in patients with IIP.

Published
2025
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23. Cutaneous T-cell-attracting chemokine as a novel biomarker for predicting prognosis of idiopathic pulmonary fibrosis: a prospective observational study

Author

20639140, 80378645, 80345222, Niwamoto, Takafumi, Handa, Tomohiro, Murase, Yuko, Nakatsuka, Yoshinari, Tanizawa, Kiminobu, Taguchi, Yoshio, Tomioka, Hiromi, Tomii, Keisuke, Kita, Hideo, Uyama, Michihiro, Tsuchiya, Michiko, Emura, Masahito, Kawamura, Tetsuji, Arai, Naoki, Arita, Machiko, Uno, Kazuko, Yoshizawa, Akihiko, Uozumi, Ryuji, Yamaguchi, Izumi, Matsuda, Fumihiko, Chin, Kazuo, Hirai, Toyohiro, 20639140, 80378645, 80345222, Niwamoto, Takafumi, Handa, Tomohiro, Murase, Yuko, Nakatsuka, Yoshinari, Tanizawa, Kiminobu, Taguchi, Yoshio, Tomioka, Hiromi, Tomii, Keisuke, Kita, Hideo, Uyama, Michihiro, Tsuchiya, Michiko, Emura, Masahito, Kawamura, Tetsuji, Arai, Naoki, Arita, Machiko, Uno, Kazuko, Yoshizawa, Akihiko, Uozumi, Ryuji, Yamaguchi, Izumi, Matsuda, Fumihiko, Chin, Kazuo, and Hirai, Toyohiro

Published
2021

32. Durvalumab, with or without tremelimumab, plus platinum–etoposide versus platinum–etoposide alone in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): updated results from a randomised, controlled, open-label, phase 3 trial

Author

Goldman, Jonathan W, primary, Dvorkin, Mikhail, additional, Chen, Yuanbin, additional, Reinmuth, Niels, additional, Hotta, Katsuyuki, additional, Trukhin, Dmytro, additional, Statsenko, Galina, additional, Hochmair, Maximilian J, additional, Özgüroğlu, Mustafa, additional, Ji, Jun Ho, additional, Garassino, Marina Chiara, additional, Voitko, Oleksandr, additional, Poltoratskiy, Artem, additional, Ponce, Santiago, additional, Verderame, Francesco, additional, Havel, Libor, additional, Bondarenko, Igor, additional, Każarnowicz, Andrzej, additional, Losonczy, György, additional, Conev, Nikolay V, additional, Armstrong, Jon, additional, Byrne, Natalie, additional, Thiyagarajah, Piruntha, additional, Jiang, Haiyi, additional, Paz-Ares, Luis, additional, Voitko, Nataliia, additional, Kazarnowicz, Andrzej, additional, Özgüroglu, Mustafa, additional, Conev, Nikolay, additional, Hochmair, Maximilian, additional, Burghuber, Otto, additional, Çiçin, Irfan, additional, Moiseenko, Vladimir, additional, Erman, Mustafa, additional, Kowalski, Dariusz, additional, Wojtukiewicz, Marek, additional, Adamchuk, Hryhoriy, additional, Vasilyev, Alexander, additional, Shevnia, Serhii, additional, Valev, Spartak, additional, Insa Molla, Maria Amelia, additional, Ursol, Grygorii, additional, Chiang, Anne, additional, Hartl, Sylvia, additional, Horváth, Zsolt, additional, Pajkos, Gábor, additional, Kim, Sang-We, additional, Smolin, Alexey, additional, Göksel, Tuncay, additional, Dakhil, Shaker, additional, Roubec, Jaromir, additional, Bogos, Krisztina, additional, Cornelissen, Robin, additional, Lee, Jong-Seok, additional, Garcia Campelo, Maria Rosario, additional, Lopez Brea, Marta, additional, Alacacioglu, Ahmet, additional, Casarini, Ignacio, additional, Ilieva, Rumyana, additional, Tonev, Ivan, additional, Somfay, Attila, additional, Bar, Jair, additional, Zer Kuch, Alona, additional, Minelli, Mauro, additional, Bartolucci, Roberta, additional, Roila, Fausto, additional, Saito, Haruhiro, additional, Azuma, Koichi, additional, Lee, Gyeong-Won, additional, Luft, Alexander, additional, Urda, Michal, additional, Delgado Mingorance, Juan Ignacio, additional, Majem Tarruella, Margarita, additional, Spigel, David, additional, Koynov, Krassimir, additional, Zemanova, Milada, additional, Panse, Jens, additional, Schulz, Christian, additional, Pápai Székely, Zsolt, additional, Sárosi, Veronika, additional, Delmonte, Angelo, additional, Bettini, Anna Cecilia, additional, Nishio, Makoto, additional, Okamoto, Isamu, additional, Hendriks, Lizza, additional, Mandziuk, Slawomir, additional, Lee, Yun Gyoo, additional, Vladimirova, Lyubov, additional, Isla Casado, Dolores, additional, Domine Gomez, Manuel, additional, Navarro Mendivil, Alejandro, additional, Morán Bueno, Teresa, additional, Wu, Shang-Yin, additional, Knoble, Jeanna, additional, Skrickova, Jana, additional, Venkova, Violetka, additional, Hilgers, Werner, additional, Laack, Eckart, additional, Bischoff, Helge, additional, Fülöp, Andrea, additional, Laczó, Ibolya, additional, Kósa, Judit, additional, Telekes, András, additional, Yoshida, Tatsuya, additional, Kanda, Shintaro, additional, Hida, Toyoaki, additional, Hayashi, Hidetoshi, additional, Maeda, Tadashi, additional, Kawamura, Tetsuji, additional, Nakahara, Yasuharu, additional, Claessens, Niels, additional, Lee, Ki Hyeong, additional, Chiu, Chao-Hua, additional, Lin, Sheng-Hao, additional, Li, Chien-Te, additional, Demirkazik, Ahmet, additional, Schaefer, Eric, additional, Nikolinakos, Petros, additional, Schneider, Jeffrey, additional, Babu, Sunil, additional, Lamprecht, Bernd, additional, Studnicka, Michael, additional, Fausto Nino Gorini, Carlos, additional, Kultan, Juraj, additional, Kolek, Vitezslav, additional, Souquet, Pierre-Jean, additional, Moro-Sibilot, Denis, additional, Gottfried, Maya, additional, Smit, Egbert, additional, Lee, Kyung Hee, additional, Kasan, Peter, additional, Chovanec, Jozef, additional, Goloborodko, Olexandr, additional, Kolesnik, Oleksii, additional, Ostapenko, Yuriy, additional, Lakhanpal, Shailendra, additional, Haque, Basir, additional, Chua, Winston, additional, Stilwill, Joseph, additional, Sena, Susana Noemi, additional, Girotto, Gustavo Colagiovanni, additional, De Marchi, Pedro Rafael Martins, additional, Martinelli de Oliveira, Fabricio Augusto, additional, Dos Reis, Pedro, additional, Krasteva, Rositsa, additional, Zhao, Yanqiu, additional, Chen, Chengshui, additional, Koubkova, Leona, additional, Robinet, Gilles, additional, Chouaid, Christos, additional, Grohe, Christian, additional, Alt, Jürgen, additional, Csánky, Eszter, additional, Somogyiné Ezer, Éva, additional, Heching, Norman Isaac, additional, Kim, Young Hak, additional, Aatagi, Shinji, additional, Kuyama, Shoichi, additional, Harada, Daijiro, additional, Nogami, Naoyuki, additional, Nokihara, Hiroshi, additional, Goto, Hisatsugu, additional, Staal van den Brekel, Agnes, additional, Cho, Eun Kyung, additional, Kim, Joo-Hang, additional, Ganea, Doina, additional, Ciuleanu, Tudor, additional, Popova, Ekaterina, additional, Sakaeva, Dina, additional, Stresko, Marian, additional, Demo, Pavol, additional, Godal, Robert, additional, Wei, Yu-Feng, additional, Chen, Yen-Hsun, additional, Hsia, Te-Chun, additional, Lee, Kang-Yun, additional, Chang, Huang-Chih, additional, Wang, Chin-Chou, additional, Dowlati, Afshin, additional, Sumey, Christopher, additional, Powell, Steven, additional, Goldman, Jonathan, additional, Zarba, Juan Jose, additional, Batagelj, Emilio, additional, Pastor, Andrea Viviana, additional, Zukin, Mauro, additional, Baldotto, Clarissa Serodio da Rocha, additional, Schlittler, Luis Alberto, additional, Calabrich, Aknar, additional, Sette, Claudia, additional, Dudov, Asen, additional, Zhou, Caicun, additional, Lena, Hervé, additional, Lang, Susanne, additional, Pápai, Zsuzsanna, additional, Goto, Koichi, additional, Umemura, Shigeki, additional, Kanazawa, Kenya, additional, Hara, Yu, additional, Shinoda, Masahiro, additional, Morise, Masahiro, additional, Hiltermann, Jeroen, additional, Mróz, Robert, additional, Ungureanu, Andrei, additional, Andrasina, Igor, additional, Chang, Gee-Chen, additional, Vynnychenko, Ihor, additional, Shparyk, Yaroslav, additional, Kryzhanivska, Anna, additional, Ross, Helen, additional, Mi, Kailhong, additional, Jamil, Rodney, additional, Williamson, Michael, additional, Spahr, Joseph, additional, Han, Zhigang, additional, Wang, Mengzhao, additional, Yang, Zhixiong, additional, Hu, Jie, additional, Li, Wei, additional, Zhao, Jun, additional, Feng, Jifeng, additional, Ma, Shenglin, additional, Zhou, Xiangdong, additional, Liang, Zongan, additional, Hu, Yi, additional, Chen, Yuan, additional, Bi, Minghong, additional, Shu, Yongqian, additional, Nan, Kejun, additional, Zhou, Jianying, additional, Zhang, Wei, additional, Ma, Rui, additional, Yang, Nong, additional, Lin, Zhong, additional, Wu, Gang, additional, Fang, Jian, additional, Zhang, Helong, additional, Wang, Kai, additional, and Chen, Zhendong, additional

Published
2021
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34. Thrombomodulin Alfa for Acute Exacerbation of Idiopathic Pulmonary Fibrosis. A Randomized, Double-Blind Placebo-controlled Trial

Author

Kondoh, Yasuhiro, primary, Azuma, Arata, additional, Inoue, Yoshikazu, additional, Ogura, Takashi, additional, Sakamoto, Susumu, additional, Tsushima, Kenji, additional, Johkoh, Takeshi, additional, Fujimoto, Kiminori, additional, Ichikado, Kazuya, additional, Matsuzawa, Yasuo, additional, Saito, Takefumi, additional, Kishi, Kazuma, additional, Tomii, Keisuke, additional, Sakamoto, Noriho, additional, Aoshima, Masahiro, additional, Araya, Jun, additional, Izumi, Shinyu, additional, Arita, Machiko, additional, Abe, Mitsuhiro, additional, Yamauchi, Hiroyoshi, additional, Shindoh, Joe, additional, Suda, Takafumi, additional, Okamoto, Masaki, additional, Ebina, Masahito, additional, Yamada, Yoshihito, additional, Tohda, Yuji, additional, Kawamura, Tetsuji, additional, Taguchi, Yoshio, additional, Ishii, Hiroshi, additional, Hashimoto, Naozumi, additional, Abe, Shinji, additional, Taniguchi, Hiroyuki, additional, Tagawa, Jun, additional, Bessho, Koji, additional, Yamamori, Natsuki, additional, and Homma, Sakae, additional

Published
2020
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40. Evaluation of Microorganisms of Humidifier Water and Humidified Air in Home Humidifier

Author

Onishi, Yasutaka, primary, Kawamura, Tetsuji, additional, Tanaka, Hiroko, additional, Takenouchi, Masaki, additional, Hirata, Nobuya, additional, Hiraoka, Ryota, additional, Hirano, Katsuya, additional, Kominami, Ryota, additional, Kume, Sachie, additional, Takahashi, Sayaka, additional, Mizuno, Shoma, additional, Higashino, Sachiko, additional, Tsukamoto, Hiroaki, additional, Sasaki, Shin, additional, and Nakahara, Yasuharu, additional

Published
2019
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48. Preoperative biopsy risk for recurrence?: A retrospective study of risk factors for recurrence of stage 1A non-small cell lung cancer

Author

Mizumori, Yasuyuki, primary, Hirata, Nobuya, additional, Hiraoka, Ryota, additional, Hirano, Katsuya, additional, Kominami, Ryota, additional, Takahashi, Sayaka, additional, Fukuda, Yasushi, additional, Onishi, Yasutaka, additional, Mizuno, Shoma, additional, Higashino, Sachiko, additional, Kato, Tomohiro, additional, Hanaoka, Kenji, additional, Kagami, Ryogo, additional, Katsuda, Rinko, additional, Yokoi, Yoko, additional, Miyake, Kohei, additional, Tsukamoto, Hiroaki, additional, Sasaki, Shin, additional, Kawamura, Tetsuji, additional, and Nakahara, Yasuharu, additional

Published
2017
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50. Effects of bronchoscopic lung volume reduction using transbronchial infusion of autologous blood and thrombin in patients with severe chronic obstructive pulmonary disease

Author

Mizumori, Yasuyuki, Mochiduki, Yoshiro, Nakahara, Yasuharu, Kawamura, Tetsuji, Sasaki, Shin, Morimoto, Akie, and Tsukamoto, Hiroaki

Subjects
Original Article
Abstract

Existing medical treatments have limitations in the management of very severe chronic obstructive pulmonary disease (COPD).We performed bronchoscopic lung volume reduction (BLVR) using transbronchial infusion of autologous blood and thrombin (BLVR with blood) in three patients with very severe COPD whose dyspnea could not be relieved by maximum medical management. Two patients underwent BLVR with blood in the left and right lungs at intervals of a half-year or a year, and one patient underwent this procedure in only the right lung. We assessed the changes in pulmonary function, exercise capacity and quality of life before and after BLVR with blood in a total of five procedures.The subjects were 58- to 74-year-old males. Their forced expiratory volume in one second (FEV1) percent predicted ranged from 14.8% to 23.4%. BLVR with blood achieved significant improvements as follows (values before → after the procedure, mean ± standard deviation): FEV1 0.45r the L → 0.76r the L (P=0.004), inspiratory capacity 1.50cityo L → 2.05±.05c L (P=0.015), 3-minute walk test 46.8nuteo m → 89.6±34.5 m (P=0.004). Lung function peaked several months after BLVR with blood and returned to nearly the baseline level in 6 months, but exercise capacity was better than that at baseline for at least 12 months. St. George's Respiratory Questionnaire (SGRQ), measured in two patients before and 12 months after the procedure, showed remarkable improvements (-15.6 and -11.9 units).BLVR with blood is an effective palliative treatment for very severe COPD.

Published
2015

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