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410 results on '"Kawakubo H"'

7. Cover Image

Author

Yamasaki, M., Kai, K., Nomura, A., Kono, H., Kawakubo, H., Sakata, Y., Mizuguchi, M., and Aishima, S.

Published
2017
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18. proposal for uniformity in classification of lymph node stations in esophageal cancer.

Author

Schuring, N, Matsuda, S, Hagens, E R C, Sano, J, Mayanagi, S, Kawakubo, H, Henegouwen, M I van Berge, Kitagawa, Y, and Gisbertz, S S

Subjects
ESOPHAGEAL cancer, LYMPH nodes, TUMOR classification, LYMPHATIC metastasis, UNIFORMITY
Abstract

The 11th edition of the "Japanese Classification of Esophageal Cancer" by the Japan Esophageal Society (JES) and the 8th edition of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control (UICC) "Cancer Staging Manual" are two separate classification systems both widely used for the clinical and pathological staging of esophageal cancer. Furthermore, the lymph node stations from these classification systems are combined for research purposes in the multinational TIGER study, which investigates the distribution pattern of lymph node metastases. The existing classification systems greatly differ with regard to number, location and anatomical boundaries of locoregional lymph node stations. The differences in these classifications cause significant heterogeneity in studies on lymph node metastases in esophageal cancer. This makes data interpretation difficult and comparison of studies challenging. In this article, we propose a match for these two commonly used classification systems and additionally for the TIGER study classification, in order to be able to compare results of studies and exchange knowledge and to make steps towards one global uniform classification system for all patients with esophageal cancer. [ABSTRACT FROM AUTHOR]

Published
2021
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29. Clinical utility of preoperative evaluation of bronchial arteries by three-dimensional computed tomographic angiography for esophageal cancer surgery

Author

Wada, T., primary, Takeuchi, H., additional, Kawakubo, H., additional, Nakamura, R., additional, Oyama, T., additional, Takahashi, T., additional, Wada, N., additional, Saikawa, Y., additional, Omori, T., additional, Jinzaki, M., additional, Kuribayashi, S., additional, and Kitagawa, Y., additional

Published
2012
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30. ChemInform Abstract: (R)-1,2,3,4-Tetrahydro(1)benzothieno(2,3-c)pyridines: Novel Optically Active Compounds with Strong 5-HT1A Receptor Binding Ability Exhibiting Anticonflict Activity and Lessening of Memory Impairment.

Author

KAWAKUBO, H., primary, TAKAGI, S., additional, YAMAURA, Y., additional, KATOH, S., additional, ISHIMOTO, Y., additional, NAGATANI, T., additional, MOCHIZUKI, D., additional, KAMATA, T., additional, and SASAKI, Y., additional

Published
2010
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45. Study on the In Vitro Assay Method for Evaluating the Inhibitory Effect of Various Substances on the Production of Plasma Kallikrein

Author

Toyomaki Y, Yago H, S. Suehiro, Nishikawa K, K. Matsumoto, and Kawakubo H

Subjects
Ketoprofen, urogenital system, Chemistry, Kallikrein, Pharmacology, Kinin, Ibuprofen, Inhibitory postsynaptic potential, biological factors, In vitro, fluids and secretions, medicine, cardiovascular diseases, Inhibitory effect, circulatory and respiratory physiology, medicine.drug
Abstract

The assay method based on the principle of kallikrein-kinin cascade was established for evaluating the inhibitory effects of various substances on the production of plasma kallikrein. In this in vitro assay, it was found that indomethacin, ketoprofen, ibuprofen and an extract obtained from inflamed rabbit skin inoculated with vaccinia virus (NSP) had the inhibitory effect on the production of plasma kallikrein. Kinins generated in the reaction mixture were measured by RIA. It was shown that the generation of kinins was also inhibited by these substances. From these results, it is hoped that this assay method may be useful for screening the substances which inhibited the production of kinin.

Published
1989

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