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510 results on '"Kawakita, Mutsushi"'

1. Efficacy of robot-assisted partial nephrectomy compared to conventional laparoscopic partial nephrectomy for completely endophytic renal tumor: a multicenter, prospective study

Author

Hinata, Nobuyuki, Murakami, Sae, Nakano, Yuzo, Hara, Isao, Kondo, Tsunenori, Hamamoto, Shuzo, Shiroki, Ryoichi, Nagayama, Jun, Kawakita, Mutsushi, Eto, Masatoshi, Ukimura, Osamu, Takenaka, Atsushi, Takagi, Toshio, Shimbo, Masaki, Azuma, Haruhito, Yoshida, Tetsuya, Furukawa, Junya, Kawamorita, Naoki, and Fujisawa, Masato

Published
2024
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2. Effects of thienopyridine class antiplatelets on bleeding outcomes following robot-assisted radical prostatectomy

Author

Kubota, Masashi, Kawakita, Mutsushi, Yoshida, Satomi, Kimura, Hiroko, Sumiyoshi, Takayuki, Yamasaki, Toshinari, Okumura, Kazuhiro, Yoshimura, Koji, Matsui, Yoshiyuki, Sugiyama, Kyohei, Okuno, Hiroshi, Segawa, Takehiko, Shimizu, Yosuke, Ito, Noriyuki, Onishi, Hiroyuki, Ishitoya, Satoshi, Soda, Takeshi, Yoshida, Toru, Uemura, Yuichi, Iwamura, Hiroshi, Okubo, Kazutoshi, Suzuki, Ryosuke, Fukuzawa, Shigeki, Akao, Toshiya, Kurahashi, Ryoma, Shimatani, Kimihiro, Sekine, Yuya, Negoro, Hiromitsu, Akamatsu, Shusuke, Kamoto, Toshiyuki, Ogawa, Osamu, Kawakami, Koji, Kobayashi, Takashi, and Goto, Takayuki

Published
2024
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3. Erdafitinib versus pembrolizumab in pretreated patients with advanced or metastatic urothelial cancer with select FGFR alterations: cohort 2 of the randomized phase III THOR trial

Author

Bastick, Patricia, Sewak, Sanjeev, Tran, Ben, Pichler, Martin, Shariat, Shahrokh, Rottey, Sylvie, Schatteman, Peter, Schrijvers, Dirk, Verschaeve, Vincent, Vulsteke, Christof, Barros Leite Ferreira, Luiza Aleixo, de Santana Gomes Andrea Juliana, Pereira, Junior, Joao Antonio, Azevedo, Sergio, Bastos, Diogo, Borges, Giuliano, Dettino, Aldo, Antonio, Pires Luis, Luz, Murilo, Martins, Suelen, Mota, Jose Mauricio, Toledo, Joseane, Eigl, Bernhard, Finch, Daygen, Gingerich, Joel, Dong, Haiying, Huang, Jian, Jin, Jie, Pan, Hongming, Sun, Zhongquan, Tian, Ye, Wan, Ben, Wu, Bin, Xu, Ting, Xue, Wei, Zhou, Fangjian, Barthelemy, Philippe, Borchiellini, Delphine, Calcagno, Fabien, Carnot, Aurelien, Cornillon, Pierre, Delva, Remy, Emambux, Sheik, Houede, Nadine, Laguerre, Brigitte, Lauridant, Géraldine, Loriot, Yohann, Mahammedi, Hakim, Maillet, Denis, Pouessel, Damien, Roubaud, Guilhem, Schlurmann-Constans, Friederike, Tosi, Diego, Zanetta, Sylvie, Banek, Severine, Feyerabend, Susan, Kramer, Mario, Niegisch, Guenther, Nuhn, Philipp, Schnabel, Marco, Wuelfing, Christian, Baka, Sofia, Bamias, Aristotelis, Fountzilas, George, Kalofonos, Harabolos, Karalis, Konstantinos, Kotsakis, Athanasios, Timotheadou, Eleni, Landherr, Laszlo, Mangel, Laszlo, Pe’er, Avivit, Levratovsky, Meital, Basso, Umberto, Battelli, Nicola, Cavo, Alessia, De Giorgi, Ugo, Doni, Laura, Galli, Luca, Gigante, Maria Olga, Guadalupi, Valentina, Maio, Michele, Milesi, Laura, Nolè, Franco, Scagliotti, Giorgio, Tortora, Giampaolo, Fukasawa, Satoshi, Harabayashi, Toru, Kamiya, Naoto, Kawahara, Takashi, Kawakita, Mutsushi, Matsubara, Nobunaki, Matsumoto, Kazumasa, Nishimura, Kazuo, Rikiya, Taoka, Shimizu, Nobuaki, Tagaki, Toshio, Kang, Taek Won, Kim, Jwa Hoon, Kim, SeHyun, Lee, Hyo Jin, Lee, Yun-Gyoo, Rha, Sun Young, Seo, Ho Kyung, Los, Maartje, Zurawski, Bogdan, Cortes, Paulo, Faustino, Catia, Vau, Nuno Sineiro, da Luz, Ricardo, Atduev, Vagif, Kirtbaya, Dmitry, Kopyltsov, Evgeny, Lykov, Aleksandr, Marat, Urmantsev, Orlov, Sergey, Penkov, Konstantin, Pirmagomedov, Albert, Semenov, Andrey, Varlamov, Sergey, Anguera, Georgia, Domenech, Montserrat, Girones, Regina, Gonzalez del Alba, Aranzazu, Milagro, Nuria Lainez, Luque, Raquel, Ortega, Esther Martínez, Mellado, Begoña, Méndez Vidal, María Jose, Fernandez, Esteban Nogales, Valderrama, Begoña Perez, Marín, Alvaro Pinto, Santander, Carmen, Huang, Yi-Hsiu, Su, Wen-Pin, Wu, Hung-Chan, Wu, WenJeng, Yu, Kai-Jie, Bilici, Ahmet, Goker, Erdem, Gumus, Mahmut, Karaoglu, Aziz, Kefeli, Umut, Köse, Fatih, Ozguroglu, Mustafa, Tural, Deniz, Turk, Haci, Yalcin, Suayib, Bondarenko, Igor, Khareba, Gennadii, Kidik, Yana, Lychkovskyy, Oleksandr, Sakalo, Valerii, Shevnia, Serghii, Stakhovskyy, Eduard, Bahl, Amit, Crabb, Simon, Powles, Thomas, Sankey, Peter, Sarwar, Mohammad, Benedetto, Pasquale, Burgess, Earle, Dawson, Nancy, Doshi, Gurjyot, Fleming, Mark, Maly, Joseph, Parikh, Mamta, Waterhouse, David, Siefker-Radtke, A.O., Matsubara, N., Park, S.H., Huddart, R.A., Burgess, E.F., Özgüroğlu, M., Valderrama, B.P., Laguerre, B., Basso, U., Triantos, S., Akapame, S., Kean, Y., Deprince, K., Mukhopadhyay, S., and Loriot, Y.

Published
2024
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5. Efficacy and safety of dose‐dense gemcitabine plus cisplatin as neoadjuvant chemotherapy for muscle‐invasive bladder cancer.

Author

Hattori, Yuto, Fujiwara, Tasuku, Hagimoto, Hiroki, Kokubun, Hidetoshi, Murata, Shiori, Makita, Noriyuki, Abe, Yohei, Kubota, Masashi, Tohi, Yoichiro, Tsutsumi, Naofumi, Shibasaki, Noboru, Inoue, Koji, Kawakita, Mutsushi, and Yamasaki, Toshinari

Subjects
LYMPHADENECTOMY, BLADDER, NEOADJUVANT chemotherapy, FILGRASTIM, OVERALL survival, BLADDER cancer
Abstract

Objective: The objective of this study was to evaluate the efficacy and safety of dose‐dense gemcitabine and cisplatin (ddGC) as neoadjuvant chemotherapy for muscle‐invasive bladder cancer (MIBC). Methods: Patients with locally advanced MIBC (cT2aN0M0‐cT4N1M0) who received ddGC between December 2017 and December 2023 were included. Regimens of ddGC with pegfilgrastim were administered every 2 weeks for 4 cycles, followed by radical cystectomy. The pathological complete response (CR) (pT0N0) and objective response (OR) (

Published
2024
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10. Photodynamic diagnosis‐assisted transurethral resection of bladder tumor for high‐risk non‐muscle invasive bladder cancer improves intravesical recurrence‐free survival (BRIGHT study).

Author

Kawai, Taketo, Matsuyama, Hideyasu, Kobayashi, Keita, Ikeda, Atsushi, Miyake, Makito, Nishimoto, Koshiro, Matsushita, Yuto, Nishiyama, Hiroyuki, Fujimoto, Kiyohide, Oyama, Masafumi, Miyake, Hideaki, Azuma, Haruhito, Inoue, Keiji, Mitsui, Takahiko, Kawakita, Mutsushi, Oyama, Chikara, Mizokami, Atsushi, Abe, Takashige, Kuroiwa, Hajime, and Kume, Haruki

Subjects
TRANSURETHRAL resection of bladder, PROPENSITY score matching, BLADDER cancer, CANCER invasiveness, CANCER relapse, DISEASE relapse
Abstract

Objectives: In a primary analysis of data from the BRIGHT study (UMIN000035712), photodynamic diagnosis‐assisted transurethral resection of bladder tumor (PDD‐TURBT) using oral 5‐aminolevulinic acid hydrochloride reduced residual tumors in high‐risk non‐muscle invasive bladder cancer (NMIBC). We aimed to evaluate the effectiveness of PDD‐TURBT for intravesical recurrence after a second transurethral resection for high‐risk NMIBC. Methods: High‐risk NMIBC patients initially treated with PDD‐TURBT (PDD group) were prospectively registered between 2018 and 2020. High‐risk patients with NMIBC who were initially treated with white‐light TURBT (WL group) were retrospectively registered. Intravesical recurrence‐free survival after the second transurethral resection was compared between the PDD and WL groups using propensity score matching analysis. Results: In total, 177 patients were enrolled in the PDD group, and 306 patients were registered in the WL group. After propensity score matching (146 cases in each group), intravesical recurrence within 1 year was significantly less frequent in the PDD group than in the WL group (p = 0.004; hazard ratio [HR] 0.44, 95% confidence interval [CI]: 0.25–0.77). In subgroup analysis, PDD‐TURBT showed a particularly high efficacy in reducing intravesical recurrence within 1 year, especially in cases of tumors measuring less than 3 cm (p = 0.003; HR 0.31, 95% CI: 0.14–0.67), absence of residual tumor at second transurethral resection (p = 0.020; HR 0.37, 95% CI: 0.16–0.86), and no postoperative intravesical Bacillus Calmette‐Guérin therapy (p < 0.001; HR 0.27, 95% CI: 0.13–0.58). Conclusions: PDD‐TURBT may reduce short‐term intravesical recurrence in patients with high‐risk NMIBC. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Totally retroperitoneal approach for robot‐assisted nephroureterectomy with bladder cuff without repositioning.

Author

Hattori, Yuto, Yamamoto, Akihiro, Nagoshi, Akihiko, Fujiwara, Tasuku, Kambe, Takanari, Igarashi, Atsushi, Akagi, Naoki, Shibasaki, Noboru, Kawakita, Mutsushi, and Yamasaki, Toshinari

Subjects
SURGICAL robots, ABDOMINAL surgery, BLADDER, LYMPHADENECTOMY, RETROPERITONEUM, RETROPUBIC prostatectomy
Abstract

Introduction: Robot‐assisted nephroureterectomy (RANU) for upper urinary tract urothelial carcinoma is typically performed via the transperitoneal approach because of limited surgical space. However, a retroperitoneal approach may be preferable in patients with a history of abdominal surgery or in those in whom pelvic lymph node dissection is unnecessary. Materials and Surgical Techniques: RANU via the retroperitoneal approach was selected for two patients diagnosed with high‐grade upper urothelial carcinoma with a history of abdominal surgery. Nephrectomy was performed in the 90° flank position, and the bed was tilted at 20°. The retroperitoneal space was extended, and the robot trocar was subsequently repositioned in the left lower quadrant. After redocking the robot, the distal ureter was dissected, and the bladder cuff was resected en bloc along with the kidney and the ureter. Neither patient had any complications within 3 months postoperatively. Discussion: By devising a new technique for trocar placement, total retroperitoneal RANU without repositioning was possible, even in a small patient. [ABSTRACT FROM AUTHOR]

Published
2024
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13. Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial

Author

Park, Se Hoon, van der Heijden, Michiel S., Necchi, Andrea, Castellano, Daniel, Bamias, Aristotelis, Lee, Jae Lyun, De Giorgi, Ugo, Bögemann, Martin, Eigl, Bernhard J., Tsiatas, Marinos, Powles, Thomas, Novikov, Andrey, Skoneczna, Iwona, Mukherjee, Som D., Suarez, Cristina, Westgeest, Hans, Fradet, Yves, Flechon, Aude, Ou, Yen-Chuan, Park, Inkeun, Matveev, Vsevolod, Pérez-Valderrama, Begoña, Cheng, Susanna, Frank, Stephen, Gurney, Howard, Anido, Urbano, Hamzaj, Alketa, Retz, Margitta, Sridhar, Srikala, Scagliotti, Giorgio Vittorio, Voortman, Jens, Alekseev, Boris, Alyasova, Anna, Komyakov, Boris, Dumez, Herlinde, Pavic, Michel, Kimura, Go, Mizokami, Atsushi, Osanto, Susanne, Arranz, Jose Angel, Piersma, Djura, Shin, Sang Joon, Karyakin, Oleg, Delgado, Ignacio, Gonzalez, Jose Luis, Pang, See-Tong, Tran, Anna, Lipatov, Oleg, Su, Wen-Pin, Flaig, Thomas, Alva, Ajjai, Park Kyong, Hwa, Kopyltsov, Evgeny, Almagro, Elena, Domenech, Monserrat, Chang, Yen-Hwa, Sautois, Brieuc, Ravaux, Andre, Aravantinos, Gerasimos, Georgoulias, Vasileios, Mulder, Sasja, Kim, Yu Jung, Kater, Fabio, Chevreau, Christine, Tagawa, Scott, Zalewski, Pawel, Joly, Florence, Loriot, Yohann, Hatiboglu, Gencay, Gianni, Luca, Morelli, Franco, Tambaro, Rosa, Hashimoto, Yasuhiro, Nosov, Alexander, Font, Albert, Rodriguez-Vida, Alejo M., Jones, Robert, Vasudev, Naveen, Srinivas, Sandhya, Zhang, Jingsong, Gil, Thierry, Finch, Daygen, Grimm, Marc-Oliver, Su, Yu-Li, Chowdhury, Simon, Hocking, Christopher, Plas, Eugen, North, Scott, Jensen, Niels Viggo, Theodore, Christine, Imkamp, Florian, Peer, Avivit, Kobayashi, Takashi, Sakai, Hideki, Sassa, Naoto, Yoshimura, Kazuhiro, Aarts, Maureen, Ferreira Castro, Ana, Topuzov, Marlen, Rodriguez, Juan Francisco, Vazquez, Federico Jose, Tsai, Yu-Chieh, Crabb, Simon, Hussain, Syed, Bendell, Johanna, Gross-Goupil, Marine, Gwenaelle, Gravis, Berger, Raanan, Statsenko, Galina, Evans, Linda, Drakaki, Alexandra, Somer, Bradley, Davis, Ian, Lynam, James, Borges, Giuliano, Dettino, Aldo, Fay, André P., Martins, Graziella, Zucca, Luis Eduardo, Agerbaek, Mads, Kalofonos, Haralambos, Rosenbaum, Eli, Enokida, Hideki, Kikukawa, Hiroaki, Nishimura, Kazuo, Tamada, Satoshi, Uemura, Motohide, Lopez, Yamil, Gietema, Jourik, Slojewski, Marcin, Fernandes, Isabel, Smolin, Alexey, Mazhar, Danish, Kalebasty, Arash Rezazadeh, Carthon, Bradley, Loidl, Wolfgang, Franke, Fabio, Girotto, Gustavo, Alimohamed, Nimira, Macfarlane, Robyn, Pappot, Helle, Niegisch, Guenter, Mavroudis, Dimitrios, Sella, Avishay, Porta, Camillo, Ebara, Shin, Nakamura, Motonobu, Obara, Wataru, Okuno, Norihiko, Shinohara, Nobuo, Sugimoto, Mikio, Suzuki, Akitaka, Tokuda, Noriaki, Uemura, Hiroji, Yamaguchi, Akito, Ramirez, Francisco, Rozanowski, Pawel, Wiechno, Pawel, Keam, Bhumsuk, Kislov, Nikolay, Plaksin, Denis, Cicin, Irfan, Kumar, Satish, Galsky, Matthew D., Petrylak, Daniel P., Rosales, Joseph, Vaishampayan, Ulka, Culine, Stephane, Papandreou, Christos, Nara, Taketoshi, Erman, Mustafa, Kreiger, Laurence, Janoski, Juliana, Rosa, Diogo, Siqueira, Mariana, Canil, Christina, Sengelov, Lisa, Tourani, Jean-Marc, Arai, Gaku, Hashine, Katsuyoshi, Kawakita, Mutsushi, Nakaigawa, Noboru, Nomi, Hayahito, Shiina, Hiroaki, Suzuki, Hiroyoshi, Yonese, Junji, Kuri, Roberto, Macedo, Eleazar, Rivera, Samuel, Villalobos Prieto, Alberto, Polakiewicz-Gilowska, Anna, Zaucha, Renata, Lopes, Fabio, Ponomarev, Roman, Pomerantz, Mark, Shariat, Shahrokh, Luk, Cynthia, Lesniewski-Kmak, Krzysztof, van der Heijden, Michiel S, Galsky, Matthew D, Petrylak, Daniel P, Ogawa, Osamu, Lee, Jae-Lyun, Eigl, Bernhard J, Mukherjee, Som D, Suárez, Cristina, Fay, André P, Duran, Ignacio, Wildsmith, Sophie, He, Philip, Angra, Natasha, Gupta, Ashok K, Levin, Wendy, and Bellmunt, Joaquim

Published
2020
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15. Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial

Author

Wong, Suet-Lai Shirley, Tan, Thean Hsiang, Hovey, Elizabeth Jane, Clay, Timothy Dudley, Wan Ng, Siobhan Su, Rutten, Annemie, Machiels, Jean-Pascal, Dumez, Herlinde, Cheng, Susanna Yee-Shan, Ferrario, Cristiano, Sengeloev, Lisa, Jensen, Niels Viggo, Thibault, Constance, Laguerre, Brigitte, Joly, Florence, Culine, Stéphane, Becht, Catherine, Niegisch, Günter, Stöckle, Michael, Grimm, Marc-Oliver, Schwentner, Christina A, Schultze-Seemann, Wolfgang, Kalofonos, Haralambos, Mavroudis, Dimitrios, Papandreou, Christos, Karavasilis, Vasilis, Révész, Janos, Rosenbaum, Eli, Leibowitz-Amit, Raya, Kejzman, Daniel, Sarid, David, Scagliotti, Giorgio Vittorio, Bracarda, Sergio, Massari, Francesco, Osawa, Takahiro, Miyajima, Naoto, Shinohara, Nobuo, Fukuta, Fumimasa, Ohyama, Chikara, Obara, Wataru, Yamashita, Shinichi, Tomita, Yoshihiko, Kawai, Koji, Fukasawa, Satoshi, Oyama, Masafumi, Yonese, Junji, Nagata, Masayoshi, Uemura, Motohide, Nishimura, Kazuo, Kawakita, Mutsushi, Tsunemori, Hiroyuki, Hashine, Katsuyoshi, Inokuchi, Junichi, Yokomizo, Akira, Nagamori, Satoshi, Lee, Hyo Jin, Park, Se Hoon, Rha, Sun Young, Kim, Yu Jung, Lee, Yun-Gyoo, Vazquez Cortés, Leticia, Lorena Urzua Flores, Claudia, Blaisse, Reinoud J.B., Erdkamp, Fransiscus L.G., Aarts, Maureen J.B., Wojcik-Tomaszewska, Joanna, Tomczak, Piotr, Sikora-Kupis, Bozena, Schenker, Michael, Herzal, Alina Amalia, Udrea, Anghel Adrian, Karlov, Petr, Fomkin, Roman, Gajate Borau, Pablo, Grande, Enrique, Delgado Mignorance, Juan Ignacio, Su, Yu-Li, Li, Jian-Ri, Lin, Chien-Liang, Lin, Chia-Chi, Yeh, Su-Peng, Erman, Mustafa, Urun, Yuksel, Golovko, Yuriy, Bondarenko, Igor, Sinielnikov, Ivan, Crabb, Simon J., Syndikus, Isabel, Huddart, Robert, Sundar, Santhanam, Chowdhury, Simon, Sarwar, Naveed, Flaig, Thomas W., Pan, Chong Xian, Schwarz, James K., Cultrera, Jennifer Lyn, Acs, Peter Istvan, Hainsworth, John D., Herms, Benjamin T., Lawler, William Eyre, Lowe, Thomas Eugene, Petrylak, Daniel P, de Wit, Ronald, Chi, Kim N, Drakaki, Alexandra, Sternberg, Cora N, Nishiyama, Hiroyuki, Castellano, Daniel, Hussain, Syed A, Fléchon, Aude, Bamias, Aristotelis, Yu, Evan Y, van der Heijden, Michiel S, Matsubara, Nobuaki, Alekseev, Boris, Necchi, Andrea, Géczi, Lajos, Ou, Yen-Chuan, Coskun, Hasan Senol, Su, Wen-Pin, Bedke, Jens, Gakis, Georgios, Percent, Ivor J, Lee, Jae-Lyun, Tucci, Marcello, Semenov, Andrey, Laestadius, Fredrik, Peer, Avivit, Tortora, Giampaolo, Safina, Sufia, Garcia del Muro, Xavier, Rodriguez-Vida, Alejo, Cicin, Irfan, Harputluoglu, Hakan, Tagawa, Scott T, Vaishampayan, Ulka, Aragon-Ching, Jeanny B, Hamid, Oday, Liepa, Astra M, Wijayawardana, Sameera, Russo, Francesca, Walgren, Richard A, Zimmermann, Annamaria H, Hozak, Rebecca R, Bell-McGuinn, Katherine M, and Powles, Thomas

Published
2020
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16. Efficacy and safety of darolutamide in Japanese patients with nonmetastatic castration-resistant prostate cancer: a sub-group analysis of the phase III ARAMIS trial

Author

Uemura, Hiroji, Matsushima, Hisashi, Kobayashi, Kazuki, Mizusawa, Hiroya, Nishimatsu, Hiroaki, Fizazi, Karim, Smith, Matthew, Shore, Neal, Tammela, Teuvo, Tabata, Ken-ichi, Matsubara, Nobuaki, Iinuma, Masahiro, Uemura, Hirotsugu, Oya, Mototsugu, Momma, Tetsuo, Kawakita, Mutsushi, Fukasawa, Satoshi, Kobayashi, Tadahiro, Kuss, Iris, Le Berre, Marie-Aude, Snapir, Amir, Sarapohja, Toni, and Suzuki, Kazuhiro

Published
2021
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19. Feasibility of laparoscopic adrenalectomy for metastatic adrenal tumors in selected patients: a retrospective multicenter study of Japanese populations

Author

Goto, Takayuki, Inoue, Takahiro, Kobayashi, Takashi, Yamasaki, Toshinari, Ishitoya, Satoshi, Segawa, Takehiko, Ito, Noriyuki, Shichiri, Yasumasa, Okumura, Kazuhiro, Okuno, Hiroshi, Kawakita, Mutsushi, Kanaoka, Toshio, Terada, Naoki, Mukai, Shoichiro, Sugi, Motohiko, Kinoshita, Hidefumi, Kamoto, Toshiyuki, Matsuda, Tadashi, and Ogawa, Osamu

Published
2020
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21. Effects of Thienopyridine Class Antiplatelets on Bleeding Outcomes Following Robot-Assisted Radical Prostatectomy

Author

Kubota, Masashi, primary, Kawakita, Mutsushi, additional, Yoshida, Satomi, additional, Kimura, Hiroko, additional, Sumiyoshi, Takayuki, additional, Yamasaki, Toshinari, additional, Okumura, Kazuhiro, additional, Yoshimura, Koji, additional, Matsui, Yoshiyuki, additional, Sugiyama, Kyohei, additional, Okuno, Hiroshi, additional, Segawa, Takehiko, additional, Shimizu, Yosuke, additional, Ito, Noriyuki, additional, Onishi, Hiroyuki, additional, Ishitoya, Satoshi, additional, Soda, Takeshi, additional, Yoshida, Toru, additional, Uemura, Yuichi, additional, Iwamura, Hiroshi, additional, Okubo, Kazutoshi, additional, Suzuki, Ryosuke, additional, Fukuzawa, Shigeki, additional, Akao, Toshiya, additional, Kurahashi, Ryoma, additional, Shimatani, Kimihiro, additional, Sekine, Yuya, additional, Negoro, Hiromitsu, additional, Akamatsu, Shusuke, additional, Kamoto, Toshiyuki, additional, Ogawa, Osamu, additional, Kawakami, Koji, additional, Kobayashi, Takashi, additional, and Goto, Takayuki, additional

Published
2023
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24. A Case of m0CRPC after Hormone Therapy for Pelvic Lymph Node Metastasis in which Salvage RARP was Effective

Author

KOKUBUN, Hidetoshi, KUBOTA, Masashi, KAMBE, Takanari, MINE, Yuta, HAGIMOTO, Hiroki, YAMAGUCHI, Ritsuki, MURATA, Shiori, MAKITA, Noriyuki, HATTORI, Yuto, ABE, Yohei, TSUTSUMI, Naofumi, YAMASAKI, Toshinari, INOUE, Koji, and KAWAKITA, Mutsushi

Subjects
Robot-assisted laparoscopic radical prostatectomy (RARP), 494.9, Castration-resistant prostate cancer, Salvage RARP
Abstract

The patient was a 63-year-old man with biopsy Gleason score of 4＋5 prostate cancer with an initial prostate specific antigen level of (PSA) 51.2ng/ml. On imaging examination, extracapsular invasion, rectal invasion, and pararectal lymph node metastasis were found (cT4N1M0). After 4 years of androgen deprivation therapy, PSA decreased to 0.631ng/ml, and then increased gradually to1.2ng/ml. Computed tomographic scan showed that the primary tumor had shrunk and lymph node metastasis had disappeared; so salvage robot-assisted resection of the prostate (RARP) was performed for non-metastatic castration-resistant prostate cancer (m0CRPC). Since PSA decreased to an undetactable level, hormone therapy was terminated at 1 year. The patient remained recurrence-free for 3 years after surgery. RARP may be effective for m0CRPC, enabling discontinuation of androgen deprivation therapy.

Published
2023

26. Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial

Author

Wong, Suet-Lai Shirley, Tan, Thean Hsiang, Hovey, Elizabeth Jane, Clay, Timothy Dudley, Ng, Siobhan Su Wan, Rutten, Annemie, Machiels, Jean-Pascal, Dumez, Herlinde, Cheng, Susanna Yee-Shan, Chi, Kim Nguyen, Ferrario, Cristiano, Sengeloev, Lisa, Jensen, Niels Viggo, Thibault, Constance, Laguerre, Brigitte, Laestadius, Fredrik, Joly, Florence, Flechon, Aude, Culine, Stéphane, Becht, Catherine, Niegisch, Günter, Stöckle, Michael, Grimm, Marc-Oliver, Gakis, Georgios, Schultze-Seemann, Wolfgang, Kalofonos, Haralambos, Mavroudis, Dimitrios, Papandreou, Christos, Karavasilis, Vasilis, Bamias, Aristotelis, Révész, Janos, Geczi, Lajos, Rosenbaum, Eli, Leibowitz-Amit, Raya, Kejzman, Daniel, Peer, Avivit, Sarid, David, Scagliotti, Giorgio Vittorio, Sternberg, Cora N, Tortora, Giampaolo, Bracarda, Sergio, Necchi, Andrea, Massari, Francesco, Osawa, Takahiro, Miyajima, Naoto, Shinohara, Nobuo, Fukuta, Fumimasa, Ohyama, Chikara, Obara, Wataru, Yamashita, Shinichi, Tomita, Yoshihiko, Kawai, Koji, Fukasawa, Satoshi, Matsubara, Nobuaki, Oyama, Masafumi, Yonese, Junji, Nagata, Masayoshi, Uemura, Motohide, Nishimura, Kazuo, Kawakita, Mutsushi, Tsunemori, Hiroyuki, Hashine, Katsuyoshi, Inokuchi, Junichi, Yokomizo, Akira, Nagamori, Satoshi, Lee, Jae-Lyun, Lee, Hyo Jin, Park, Se Hoon, Rha, Sun Young, Kim, Yu Jung, Lee, Yun-Gyoo, Cortés, Leticia Vazquez, Flores, Claudia Lorena Urzua, Blaisse, Reinoud J B, van der Heijden, Michiel S, de Wit, Ronald, Erdkamp, Fransiscus L G, Aarts, Maureen J B, Wojcik-Tomaszewska, Joanna, Tomczak, Piotr, Sikora-Kupis, Bozena, Schenker, Michael, Herzal, Alina Amalia, Udrea, Anghel Adrian, Karlov, Petr, Safina, Sufia Z, Alekseev, Boris, Semenov, Andrey, Fomkin, Roman, Pulido, Enrique Grande, Del Muro, F Xavier García, Mignorance, Juan Ignacio Delgado, Gauna, Daniel Castellano, Rodríguez-Vida, Alejo, Su, Yu-Li, Ou, Yen-Chuan, Lin, Chien-Liang, Su, Wen-Pin, Lin, Chia-Chi, Yeh, Su-Peng, Çiçin, Irfan, Harputluoglu, Hakan, Erman, Mustafa, Coskun, Hasan Senol, Urun, Yuksel, Golovko, Yurii, Bondarenko, Igor, Sinielnikov, Ivan, Powles, Thomas, Crabb, Simon, Syndikus, Isabel, Huddart, Robert, Sundar, Santhanam, Chowdhury, Simon, Sarwar, Naveed, Drakaki, Alexandra, Flaig, Thomas, Pan, Chong Xian, Petrylak, Daniel, Schwarz, James, Percent, Ivor, Cultrera, Jennifer, Hainsworth, John, Herms, Benjamin, Lawler, William, Lowe, Thomas, Tagawa, Scott, Aragon-Ching, Jeanny, Vaishampayan, Ulka, Petrylak, Daniel P, Chi, Kim N, Nishiyama, Hiroyuki, Castellano, Daniel, Hussain, Syed, Fléchon, Aude, Yu, Evan Y, Géczi, Lajos, Hegemann, Miriam, Percent, Ivor J, Tucci, Marcello, Safina, Sufia, del Muro, Xavier Garcia, Rodriguez-Vida, Alejo, Cicin, Irfan, Widau, Ryan C, Liepa, Astra M, Walgren, Richard A, Hamid, Oday, Zimmermann, Annamaria H, and Bell-McGuinn, Katherine M

Published
2017
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Author

KAMBE, Takanari, YAMASAKI, Toshinari, NAGOSHI, Akihiko, FUJIWARA, Tasuku, MINE, Yuta, HAGIMOTO, Hiroki, HATTORI, Yuto, ABE, Yohei, YAMASHITA, Daisuke, TSUTSUMI, Naofumi, KAWAKITA, Mutsushi, KAMBE, Takanari, YAMASAKI, Toshinari, NAGOSHI, Akihiko, FUJIWARA, Tasuku, MINE, Yuta, HAGIMOTO, Hiroki, HATTORI, Yuto, ABE, Yohei, YAMASHITA, Daisuke, TSUTSUMI, Naofumi, and KAWAKITA, Mutsushi

Abstract

Contrast-enhanced computed tomography (CT) revealed a multilocular cystic mass extending from the level of the renal artery origin to the internal and external iliac artery regions in a woman in her 40s who presented with vomiting and diarrhea. A percutaneous biopsy was performed, and histopathological examination revealed bundle-like proliferations of spindle-shaped cells with oval nuclei in acidophilic cytoplasm. Immunohistochemical staining was positive for HMB-45, alpha-smooth muscle actin, E-cadherin, and estrogen and progesterone receptors; the provisional diagnosis was perivascular epithelioid cell tumor. Considering the patient's age and sex, the final diagnosis was primary retroperitoneal lymphangioleiomyomatosis (LAM). She did not meet the diagnostic criteria for tuberous sclerosis complex and was considered to have sporadic LAM. As complete surgical resection was considered to be impossible and no lung lesions, which indicate poor prognosis, were observed, we decided to keep her under surveillance. The patient was asymptomatic, with no significant changes on imaging for 6 months.

Published
2023

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Author

KOKUBUN, Hidetoshi, KUBOTA, Masashi, KAMBE, Takanari, MINE, Yuta, HAGIMOTO, Hiroki, YAMAGUCHI, Ritsuki, MURATA, Shiori, MAKITA, Noriyuki, HATTORI, Yuto, ABE, Yohei, TSUTSUMI, Naofumi, YAMASAKI, Toshinari, INOUE, Koji, KAWAKITA, Mutsushi, KOKUBUN, Hidetoshi, KUBOTA, Masashi, KAMBE, Takanari, MINE, Yuta, HAGIMOTO, Hiroki, YAMAGUCHI, Ritsuki, MURATA, Shiori, MAKITA, Noriyuki, HATTORI, Yuto, ABE, Yohei, TSUTSUMI, Naofumi, YAMASAKI, Toshinari, INOUE, Koji, and KAWAKITA, Mutsushi

Abstract

The patient was a 63-year-old man with biopsy Gleason score of 4＋5 prostate cancer with an initial prostate specific antigen level of (PSA) 51.2ng/ml. On imaging examination, extracapsular invasion, rectal invasion, and pararectal lymph node metastasis were found (cT4N1M0). After 4 years of androgen deprivation therapy, PSA decreased to 0.631ng/ml, and then increased gradually to1.2ng/ml. Computed tomographic scan showed that the primary tumor had shrunk and lymph node metastasis had disappeared; so salvage robot-assisted resection of the prostate (RARP) was performed for non-metastatic castration-resistant prostate cancer (m0CRPC). Since PSA decreased to an undetactable level, hormone therapy was terminated at 1 year. The patient remained recurrence-free for 3 years after surgery. RARP may be effective for m0CRPC, enabling discontinuation of androgen deprivation therapy.

Published
2023

33. Treatment strategies and outcomes in a long‐term registry study of patients with high‐risk metastatic hormone‐naïve prostate cancer in Japan: An interim analysis of the J‐ROCK study

Author

Uemura, Hirotsugu, primary, Matsumoto, Rikiya, additional, Mizokami, Atsushi, additional, Miyake, Hideaki, additional, Uemura, Hiroji, additional, Matsuyama, Hideyasu, additional, Nakamura, Kazuyoshi, additional, Saito, Kazutaka, additional, Kawakita, Mutsushi, additional, Takeshita, Hideki, additional, Koroki, Yosuke, additional, Ono, Shintaro, additional, Murota, Maiko, additional, Ito, Miku, additional, Kamoto, Toshiyuki, additional, and Fujimoto, Kiyohide, additional

Published
2022
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35. Effect of continued perioperative antithrombotic therapy on bleeding outcomes following laparoscopic nephrectomy and nephroureterectomy

Author

Kubota, Masashi, primary, Matsuoka, Takashi, additional, Mine, Yuta, additional, Hagimoto, Hiroki, additional, Kokubun, Hidetoshi, additional, Murata, Shiori, additional, Makita, Noriyuki, additional, Hattori, Yuto, additional, Suzuki, Issei, additional, Abe, Yohei, additional, Tohi, Yoichiro, additional, Tsutsumi, Naofumi, additional, Yamasaki, Toshinari, additional, Inoue, Koji, additional, and Kawakita, Mutsushi, additional

Published
2022
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36. Antimicrobial prophylaxis to prevent perioperative infection in urological surgery: a multicenter study

Author

Togo, Yoshikazu, Yamamoto, Shingo, Tanaka, Shiro, Kanematsu, Akihiro, Ogawa, Osamu, Miyazato, Minoru, Saito, Hideo, Arai, Yoichi, Hoshi, Akio, Terachi, Toshiro, Fukui, Katsuya, Kinoshita, Hidefumi, Matsuda, Tadashi, Yamashita, Motoki, Kakehi, Yoshiyuki, Tsuchihashi, Kazunari, Sasaki, Miharu, Ishitoya, Satoshi, Onishi, Hiroyuki, Takahashi, Akira, Ogura, Keiji, Mishina, Mutsuki, Okuno, Hiroshi, Oida, Tomoyuki, Horii, Yasuki, Hamada, Akihiro, Okasyo, Kosuke, Okumura, Kazuhiro, Iwamura, Hiroshi, Nishimura, Kazuo, Manabe, Yumi, Hashimura, Takayuki, Horikoshi, Mikito, Mishima, Takao, Okada, Takuya, Sumiyoshi, Takayuki, Kawakita, Mutsushi, Kanamaru, Sojun, Ito, Noriyuki, Aoki, Dai, Kawaguchi, Risaku, Yamada, Yusuke, Kokura, Koji, Nagai, Jun, Kondoh, Nobuyuki, Kajio, Keisuke, and Yoshimoto, Tetsuro

Published
2013
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38. Simple Methods to Prevent Postoperative Inguinal Hernia after Extraperitoneal and Transperitoneal Robot-Assisted Radical Prostatectomy

Author

Inoue, Koji, Murata, Shiori, Makita, Noriyuki, Suzuki, Issei, Kubota, Masashi, Tohi, Yoichiro, Sugino, Yoshio, and Kawakita, Mutsushi

Subjects
Prostatectomy, Inguinal hernia, Patent processus vaginalis, 494.9
Abstract

Herein we present simple methods to prevent postoperative inguinal hernia (IH) after extraperitoneal and transperitoneal robot-assisted radical prostatectomy (RARP). Among 275 patients who underwent RARP between January 2014 and December 2016 at our institution, we evaluated 143 and 115 patients who underwent extraperitoneal-RARP (e-RARP) and transperitoneal-RARP (t-RARP), respectively, after excluding those with intraoperative detection of IH (17 patients). In the e-RARP group, all 143 patients (286 groins) underwent an IH prevention procedure. In the t-RARP group, the first 22 patients (44 groins) did not undergo an IH prevention procedure, whereas 29 patients (37 groins) with patent processus vaginalis (PPV) among the last 93 patients underwent the procedure. The IH prevention procedure during e-RARP included release of the vas deferens from the peritoneum and spermatic cord, and peritoneal dissection of the spermatic cord at the internal inguinal ring. The IH prevention procedure during t-RARP included release of the vas deferens from the peritoneum and spermatic cord, complete circumferential dissection of the peritoneum around the PPV at the level of the internal inguinal ring, and ligation of the PPV with a Hem-o- Loc○R clip. In the e-RARP group, postoperative IH occurred in 3 of the 143 patients (1.9%) during the follow-up period of 22.0±9.2 months. In the first subgroup of t-RARP, postoperative IH developed in 4 of the 22 patients (18%) during the follow-up period of 33.1±12.1 months, whereas in the last t-RARP group, postoperative IH developed in 3 of the 93 patients (3.3%) during the follow-up period of 20.1±8.6 months. Different IH prevention procedures performed in patients undergoing e-RARP and t-RARP were simple and effective in preventing postoperative IH.

Published
2020

39. Necessity of Pelvic Drain Placement after Robot-Assisted Radical Prostatectomy

Author

Makita, Noriyuki, Kubota, Masashi, Murata, Shiori, Suzuki, Issei, Tohi, Yoichiro, Sugino, Yoshio, Inoue, Koji, and Kawakita, Mutsushi

Subjects
Prostatectomy, Pelvic drain, 494.9
Abstract

Sixty eight patients had robot-assisted radical prostatectomy (RARP) from January 2016 to April 2017 with estimated blood loss of less than 500 ml. We compared the postoperative complication rates and the length of hospital stay between 34 of these patients who had pelvic drain placement (PD group), and the remaining 34 patients who had no drain placement (ND group). The approach was intraperitoneal in 25 patients in each group. The PD and ND groups were comparable for age (69.5 vs 70 yrs, P=0.459), clinical Gleason Score (6/7/≧8) 2/17/15 vs 3/8/23 (P=0.077), clinical stage (1c/2/3) 3/25/6 vs 1/25/8 (p=0. 539), operative time (311 vs 309 min, P=0.868), and estimated blood loss (p=0.166). The PD group had significantly higher median PSA level than the ND group (8.01 vs 6.25 ng/ml, P=0.023). Incidence of 30- day overall complications in the PD group (35 events) was lower than that in the ND group (38 events). All complications were classified as Clavien Dindo grade I. The postoperative hospital stay was 8 days in the PD group and 7 days in the ND group, showing no prolongation in the ND group. Pelvic drainage may be omitted after RARP without increasing postoperative complications or prolonging the hospital stay.

Published
2020

40. Complete remission of renal cell carcinoma with lung carcinomatous lymphangiosis after primary therapy with immune checkpoint inhibitors followed by partial nephrectomy for surgical consolidation

Author

Kambe, Takanari, primary, Yamasaki, Toshinari, additional, Mine, Yuta, additional, Hagimoto, Hiroki, additional, Kokubun, Hidetoshi, additional, Kubota, Masashi, additional, Tsutsumi, Naofumi, additional, Inoue, Koji, additional, Hara, Shigeo, additional, and Kawakita, Mutsushi, additional

Published
2022
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41. Bladder cancer prospective cohort study on high‐risk non‐muscle invasive bladder cancer after photodynamic diagnosis‐assisted transurethral resection of the bladder tumor (BRIGHT study)

Author

Kobayashi, Keita, primary, Matsuyama, Hideyasu, additional, Kawai, Taketo, additional, Ikeda, Atsushi, additional, Miyake, Makito, additional, Nishimoto, Koshiro, additional, Matsushita, Yuto, additional, Komura, Kazumasa, additional, Abe, Takashige, additional, Kume, Haruki, additional, Nishiyama, Hiroyuki, additional, Fujimoto, Kiyohide, additional, Oyama, Masafumi, additional, Miyake, Hideaki, additional, Inoue, Keiji, additional, Mitsui, Takahiko, additional, Kawakita, Mutsushi, additional, Ohyama, Chikara, additional, Mizokami, Atsushi, additional, and Kuroiwa, Hajime, additional

Published
2022
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42. Reduction of residual tumors by photodynamic diagnosis-assisted TURBT using 5-aminolevulinic acid for high-risk nonmuscle-invasive bladder cancer (BRIGHT study).

Author

Kawai, Taketo, primary, Kume, Haruki, additional, Inoue, Keiji, additional, Fujimoto, Kiyohide, additional, Oyama, Masafumi, additional, Miyake, Hideaki, additional, Azuma, Haruhito, additional, Nishiyama, Hiroyuki, additional, Shinohara, Nobuo, additional, Ohyama, Chikara, additional, Mitsui, Takahiko, additional, Mizokami, Atsushi, additional, Kawakita, Mutsushi, additional, and Matsuyama, Hideyasu, additional

Published
2022
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43. Surgical and Functional Outcomes on Omitting Cortical Renorrhaphy During Robot-Assisted Versus Laparoscopic Partial Nephrectomy: A Match-Paired Analysis

Author

Kubota, Masashi, primary, Yamasaki, Toshinari, additional, Murata, Shiori, additional, Abe, Yohei, additional, Tohi, Yoichiro, additional, Mine, Yuta, additional, Hagimoto, Hiroki, additional, Kokubun, Hidetoshi, additional, Suzuki, Issei, additional, Tsutsumi, Naofumi, additional, Inoue, Koji, additional, and Kawakita, Mutsushi, additional

Published
2022
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44. PROSTATE-SPECIFIC ANTIGEN DENSITY IS THE MOST APPROPRIATE FACTOR FOR DETECTING UNFAVORABLE PATHOLOGY AFTER RADICAL PROSTATECTOMY IN MEN ELIGIBLE FOR ACTIVE SURVEILLANCE FROM MUTLI-INSTITUTIONAL STUDY: MP57-08

Author

Inoue, Takahiro, Mizuno, Kei, Kinoshita, Hidefumi, Yano, Toshifumi, Kawanishi, Hiroaki, Kanda, Hideki, Terada, Naoki, Kamba, Tomomi, Okumura, Kazuhiro, Kawakita, Mutsushi, Ogura, Keiji, Sugimura, Yoshiki, Matsuda, Tadashi, and Ogawa, Osamu

Published
2016
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45. Robot‐assisted transperitoneal reconstruction of a retrocaval ureter: A report of two cases.

Author

Mine, Yuta, Yamasaki, Toshinari, Kambe, Takanari, Hagimoto, Hiroki, Kokubun, Hidetoshi, Hattori, Yuto, Abe, Yohei, Kubota, Masashi, Tsutsumi, Naohumi, and Kawakita, Mutsushi

Subjects
URETERS, SURGICAL robots, KIDNEY stones, LAPAROSCOPIC surgery, URETERIC obstruction
Abstract

A retrocaval ureter (RCU) is a rare cause of congenital ureteral obstruction that often requires surgical repair. We report two cases of RCU in adults treated with robot‐assisted laparoscopic surgery. In both cases, we performed robotic ureteroureterostomy with dissection of the entire length of the retrocaval portion of the right ureter without complications. In the second case, renal stone removal was simultaneously performed. The robot‐assisted procedure we performed could be considered safe and feasible for the surgical repair of an RCU. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Effect of continued perioperative antithrombotic therapy on bleeding outcomes following laparoscopic nephrectomy and nephroureterectomy.

Author

Kubota, Masashi, Matsuoka, Takashi, Mine, Yuta, Hagimoto, Hiroki, Kokubun, Hidetoshi, Murata, Shiori, Makita, Noriyuki, Hattori, Yuto, Suzuki, Issei, Abe, Yohei, Tohi, Yoichiro, Tsutsumi, Naofumi, Yamasaki, Toshinari, Inoue, Koji, and Kawakita, Mutsushi

Subjects
FIBRINOLYTIC agents, NEPHRECTOMY, BLOOD loss estimation, SURGICAL blood loss, LAPAROSCOPIC surgery, HEMORRHAGE
Abstract

Introduction: In this study, we aimed to assess the impact of perioperative continuation of antithrombotic therapy on bleeding and complications in patients undergoing laparoscopic radical nephrectomy (LRN) and nephroureterectomy (LNU). Methods: This was a retrospective observational study. Patients who underwent LRN and LNU between January 2017 and July 2019 at our institution were recruited. All patients taking antithrombotic agents continued taking them during the perioperative phase (AA group). Surgical outcomes of patients in the AA group were compared with those of patients who were not taking antithrombotic agents (NA group). The primary outcome was the rate of bleeding complications. Secondary outcomes included intraoperative estimated blood loss, transfusion rate, and complications for up to 90 days. Results: A total of 100 patients were included in the analysis, with 36 and 64 patients assigned to the AA and NA groups, respectively. Patients in the AA group were found to have more severe comorbidities than those in the NA group, with a Charlson Comorbidity Index ≥5, totaling 14 (39%) and 12 (19%), respectively (P =.03). According to surgical outcomes, none of the patients in the AA group required secondary procedures for bleeding complications. Moreover, there were no significant differences between the groups in intraoperative blood loss, hemoglobin deficit, rate of perioperative transfusion, readmission rate, or high‐grade complications. Discussion: These results indicate that perioperative use of antithrombotic agents does not increase the risk of bleeding and can be considered safe during LRN and LNU. [ABSTRACT FROM AUTHOR]

Published
2023
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48. The Safety of Laparoscopic Radical Cystectomy during Initial Phases in a Japanese Multicenter Cohort

Author

Kanno, Toru, Inoue, Takahiro, Ito, Katsuhiro, Kono, Yuka, Kawanishi, Hiroaki, Okumura, Kazuhiro, Yamada, Hitoshi, Kubota, Masashi, Kawakita, Mutsushi, Fujii, Masato, Terada, Naoki, Kamoto, Toshiyuki, Shimizu, Yosuke, Ito, Noriyuki, Tanoue, Kenichiro, Kamba, Tomomi, Kobori, Go, Moroi, Seiji, Hamada, Akihiro, Masui, Kimihiko, Shichiri, Yasumasa, Shibasaki, Noboru, Akao, Toshiya, Sawada, Atsuro, Saito, Ryoich, Kobayashi, Takashi, Ogawa, Osamu, 大文字会臨床データベース(Dai-CAD), and Daimonji Clinical Application Database (Dai-CAD)

Subjects
Japanese multicenter study, Initial phases, 494.9, Laparoscopic radical cystectomy, Treatment outcome
Abstract

We evaluated the safety of laparoscopic radical cystectomy (LRC) during initial phases and its learning curve in a Japanese multicenter cohort by studying 436 patients who underwent LRC with no robot assistance at 10 institutions in Japan. We divided the patients into three groups according to cumulative surgical volume at each institution (first 10 cases, 11-30 cases, after 31 cases in each institution), and compared perioperative and pathologic variables among the three groups. The first, second, and third groups included 100, 166, 170 patients, respectively. The preoperative variables were similar in the three groups except for the rate of neoadjuvant chemotherapy. The methods of LRC procedure, such as urinary diversion, the extent of lymph node dissection, and concomitant urethrectomy or nephroureterectomy, were similar in the three groups. Mean operative time was 629, 562 and 531 minutes, respectively, and mean blood loss was 755, 650 and 435 ml, respectively. Both values decreased over time with the institution's experience. There was no significant difference among the three groups in the rate of positive surgical margin, the number of retrieved lymph nodes, and the rate of intra- and postoperative complications. LRC was safely performed during initial phases with an acceptable complication rate and without compromising oncological results, although operative time was longer and blood loss increased.

Published
2019

49. Traumatic Adrenal Injury : A Single-Institution Experience

Author

Tohi, Yoichiro, Murata, Shiori, Makita, Noriyuki, Suzuki, Issei, Kubota, Masashi, Sugino, Yoshio, Inoue, Koji, and Kawakita, Mutsushi

Subjects
Blunt injury, Traumatic adrenal injury, 494.9
Abstract

Traumatic adrenal injury is quite rare. From January 2008 to March 2018, out of 287 patients with genitourinary trauma, 23 patients (8%) were diagnosed with traumatic adrenal injury at Kobe City Medical Center General Hospital. We retrospectively reviewed the medical records and assessed the traumatic category, image findings and outcome. All 23 patients were bluntly injured. The causes of traumatic adrenal injury were motor vehicle accident (11 patients : 48%) and falls (9 patients : 39%). The majority of injuries occurred on the right side (18 patients : 78%). Associated injuries occurred in all 23 patients, most frequently in the liver (57%) and ribs (57%). Extravasation of contrast materials was identified on computed tomography (CT) in 4 patients (17%). Although 22 patients (96%) were conservatively managed, only 1 patient was treated by transcatherter arterial embolization because of hypotension. One patient died of intraabdominal bleeding. To our knowledge, the present study is the largest on traumatic adrenal injury in Japan.

Published
2019

50. A Case of Systemic Polyarteritis Nodosa Presenting with Scrotal Pain

Author

Suzuki, Issei, Kubota, Masashi, Uehara, Keiichiro, Shimizu, Hayato, Murata, Shiori, Makita, Noriyuki, Suzuki, Ryosuke, Tohi, Yoichiro, Yamashita, Daisuke, Sugino, Yoshio, Inoue, Koji, and Kawakita, Mutsushi

Subjects
Scrotal pain, Polyarteritis nodosa, 494.9
Abstract

A 76-year-old man with a history of hypertension was admitted with high fever and left scrotal pain. Laboratory findings revealed high serum C-reactive protein levels. The left epididymis appeared to be swollen on computed tomography. The patient was diagnosed with bacterial epididymitis and treatment with antibiotics was initiated. Despite treatment, his left scrotal pain and fever did not improve. Additionally, he developed right scrotal and posterior neck pain. For histopathological diagnosis, a left high orchiectomy was performed and the findings revealed thickened arteriolar walls with infiltration of inflammatory cells around the testis, leading to a final diagnosis of systemic polyarteritis nodosa. Treatment with steroids led to complete resolution of the patient’s systemic pain and inflammation.

Published
2019

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