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2. Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration

Author

Fujii, Yuki, Uchida, Daisuke, Sato, Ryosuke, Obata, Taisuke, Akihiro, Matsumi, Miyamoto, Kazuya, Morimoto, Kosaku, Terasawa, Hiroyuki, Yamazaki, Tatsuhiro, Matsumoto, Kazuyuki, Horiguchi, Shigeru, Tsutsumi, Koichiro, Kato, Hironari, Inoue, Hirofumi, Cho, Ten, Tanimoto, Takayoshi, Ohto, Akimitsu, Kawahara, Yoshiro, and Otsuka, Motoyuki

Published
2024
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3. Virtual indigo carmine chromoendoscopy images: a novel modality for peroral cholangioscopy using artificial intelligence technology (with video)

Author

Sato, Ryosuke, Matsumoto, Kazuyuki, Kinugasa, Hideaki, Tomiya, Masahiro, Tanimoto, Takayoshi, Ohto, Akimitsu, Harada, Kei, Hattori, Nao, Obata, Taisuke, Matsumi, Akihiro, Miyamoto, Kazuya, Morimoto, Kosaku, Terasawa, Hiroyuki, Fujii, Yuki, Uchida, Daisuke, Tsutsumi, Koichiro, Horiguchi, Shigeru, Kato, Hironari, Kawahara, Yoshiro, and Otsuka, Motoyuki

Published
2024
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4. Metachronous primary gastric cancer after endoscopic resection in patients with esophageal squamous cell carcinoma

Author

Hirao, Motohiro, Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Suzuki, Haruhisa, Furue, Yasuaki, Yamamoto, Keiko, Doyama, Hisashi, Koike, Tomoyuki, Tamaoki, Masashi, Kawata, Noboru, Kawahara, Yoshiro, Katagiri, Atsushi, Ogata, Takashi, Yamanouchi, Takenori, Kiyokawa, Hirofumi, Kawakubo, Hirofumi, Konno, Maki, Ishikawa, Hideki, Yokoyama, Akira, and Muto, Manabu

Published
2023
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6. Long-term Survival After Endoscopic Resection For Gastric Cancer: Real-world Evidence From a Multicenter Prospective Cohort

Author

Mashimo, Yumi, Ishigooka, Masahiro, Fukase, Kazutoshi, Mizuguchi, Yasuhiko, Suzuki, Haruhisa, Ono, Hiroyuki, Hirasawa, Toshiaki, Takeuchi, Yoji, Ishido, Kenji, Hoteya, Shu, Yano, Tomonori, Tanaka, Shinji, Toya, Yosuke, Nakagawa, Masahiro, Toyonaga, Takashi, Takemura, Kenichi, Hirasawa, Kingo, Matsuda, Mitsuru, Yamamoto, Hironori, Tsuji, Yosuke, Hashimoto, Satoru, Yuki, Maeda, Oyama, Tsuneo, Takenaka, Ryuta, Yamamoto, Yoshinobu, Naito, Yuji, Yamamoto, Katsumi, Kobayashi, Nozomu, Kawahara, Yoshiro, Hirano, Masaaki, Koizumi, Shigeto, Hori, Shinichiro, Tajika, Masahiro, Hikichi, Takuto, Yao, Kenshi, Yokoi, Chizu, Ohnita, Ken, Hisanaga, Yasuhiro, Sumiyoshi, Tetsuya, Kitamura, Shinji, Tanaka, Hisao, Shimoda, Ryo, Shimazu, Taichi, Takizawa, Kohei, Tanabe, Satoshi, Kondo, Hitoshi, Iishi, Hiroyasu, Ninomiya, Motoki, and Oda, Ichiro

Published
2023
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9. White Globe Appearance–Like Findings Indicating Intralymphatic Cancer Involvement Beneath the Epithelium in Gastric Cancer.

Author

Maruyama, Hiroki, Yamagata, Taku, Kanno, Yoshihide, Shimizu, Takeshi, Itasaka, Takuho, Fujishima, Fumiyoshi, Sawai, Takashi, Ito, Kei, and Kawahara, Yoshiro

Subjects
STOMACH cancer, METASTASIS, DIGESTIVE system endoscopic surgery, CARCINOMA, EPITHELIUM
Abstract

A 75‐year‐old female was diagnosed with a type 0‐I, moderately differentiated, early gastric carcinoma on the posterior wall of the middle gastric body during esophagogastroduodenoscopy (EGD). Several small whitish structures, referred to as white globe appearances (WGAs), were noted on the oral side outside the demarcation line of the cancerous protrusion. Although this area was flat without cancerous mucosal changes on the surface, subepithelial cancer extension was suspected. The histopathology of the resected specimen revealed that the carcinoma with submucosal invasion had significant lymphatic invasion with submucosal lateral extent along lymphatic vessels. In some areas, the carcinoma within the lymphatic vessels regressed from the submucosal layer towards the mucosal lamina propria, penetrating the muscularis mucosas. The intralymphatic carcinoma reaching just beneath the epithelium was considered to manifest WGA features during endoscopy. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Endoscopic and Histological Gastritis in University Students with Helicobacter pylori Infection

Author

Okanoue, Shotaro, primary, Sakae, Hiroyuki, additional, Yokota, Kenji, additional, Tanaka, Takehiro, additional, Obayashi, Yuka, additional, Abe, Makoto, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Kawahara, Yoshiro, additional, Yanai, Hiroyuki, additional, and Okada, Hiroyuki, additional

Published
2024
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13. Alcohol consumption, multiple Lugol‐voiding lesions, and field cancerization.

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Yano, Tomonori, Suzuki, Haruhisa, Furue, Yasuaki, Yamamoto, Keiko, Doyama, Hisashi, Koike, Tomoyuki, Tamaoki, Masashi, Kawata, Noboru, Hirao, Motohiro, Kawahara, Yoshiro, Ogata, Takashi, Katagiri, Atsushi, Yamanouchi, Takenori, Kiyokawa, Hirofumi, Kawakubo, Hirofumi, Konno, Maki, Yokoyama, Akira, and Ohashi, Shinya

Published
2024
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16. Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration

Author

Fujii, Yuki, primary, Uchida, Daisuke, additional, Sato, Ryosuke, additional, Obata, Taisuke, additional, Matsumi, Akihiro, additional, Miyamoto, Kazuya, additional, Morimoto, Kosaku, additional, Terasawa, Hiroyuki, additional, Yamazaki, Tatsuhiro, additional, Matsumoto, Kazuyuki, additional, Horiguchi, Shigeru, additional, Tsutsumi, Koichiro, additional, Kato, Hironari, additional, Cho, Ten, additional, Tanimoto, Takayoshi, additional, Ohto, Akimitsu, additional, Inoue, Hirofumi, additional, Kawahara, Yoshiro, additional, and Otsuka, Motoyuki, additional

Published
2023
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17. MO66-2 The use of ramucirumab before nivolumab may improve survival for unresectable advanced or recurrent gastric cancer

Author

Hirata, Shoichiro, primary, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Inoo, Shoko, additional, Kuraoka, Sakiko, additional, Matsueda, Katsunori, additional, Okanoue, Shotaro, additional, Satomi, Takuya, additional, Hamada, Kenta, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, and Kawahara, Yoshiro, additional

Published
2023
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18. Optimal Bowel Preparation Method to Visualize the Distal Ileum via Small Bowel Capsule Endoscopy

Author

Kametaka, Daisuke, primary, Ito, Mamoru, additional, Kawano, Seiji, additional, Ishiyama, Shuhei, additional, Fujiwara, Akiko, additional, Nasu, Junichirou, additional, Yoshioka, Masao, additional, Shiode, Junji, additional, Yamamoto, Kazuhide, additional, Iwamuro, Masaya, additional, Kawahara, Yoshiro, additional, Okada, Hiroyuki, additional, and Otsuka, Motoyuki, additional

Published
2023
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21. Scattered Tiny Whitish Protrusions in the Stomach Are a Clue to the Diagnosis of Autoimmune Gastritis

Author

Iwamuro, Masaya, Tanaka, Takehiro, Hamada, Kenta, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Kawano, Seiji, Kawahara, Yoshiro, and Okada, Hiroyuki

Subjects
small white protrusions, mucosal lesions, esophagogastroduodenoscopy, scattered lesions, autoimmune gastritis
Abstract

Herein, we report two patients with autoimmune gastritis who had undergone multiple esophagogastroduodenoscopy procedures for 17 and 9 years, respectively, before their diagnosis. Instead, they had been diagnosed with and treated for Helicobacter pylori-associated gastritis. The correct diagnosis was made when scatterings of tiny whitish protrusions in the gastric mucosa were detected on esophagogastroduodenoscopy. Our findings suggest that scattered tiny whitish bumps may be a clue to the diagnosis of autoimmune gastritis.

Published
2023

22. Association of screening tool scores with overall survival in older patients with unresectable gastrointestinal or biliary pancreatic cancer: A retrospective study

Author

Inoo, Shoko, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Horiguchi, Shigeru, Kato, Hironari, Yamasaki, Yasushi, Hirata, Shoichiro, Kuraoka, Sakiko, Matsueda, Katsunori, Okanoue, Shotaro, Satomi, Takuya, Hamada, Kenta, Iwamuro, Masaya, Kawano, Seiji, Kawahara, Yoshiro, Okada, Hiroyuki, and Otsuka, Motoyuki

Published
2024
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23. Endoscopic features of gastric neuroendocrine carcinoma

Author

Matsueda, Katsunori, primary, Uedo, Noriya, additional, Kitamura, Masanori, additional, Shichijo, Satoki, additional, Maekawa, Akira, additional, Kanesaka, Takashi, additional, Takeuchi, Yoji, additional, Higashino, Koji, additional, Ishihara, Ryu, additional, Michida, Tomoki, additional, Kawano, Seiji, additional, and Kawahara, Yoshiro, additional

Published
2023
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25. Alcohol consumption, multiple Lugol‐voiding lesions, and field cancerization

Author

Katada, Chikatoshi, primary, Yokoyama, Tetsuji, additional, Yano, Tomonori, additional, Suzuki, Haruhisa, additional, Furue, Yasuaki, additional, Yamamoto, Keiko, additional, Doyama, Hisashi, additional, Koike, Tomoyuki, additional, Tamaoki, Masashi, additional, Kawata, Noboru, additional, Hirao, Motohiro, additional, Kawahara, Yoshiro, additional, Ogata, Takashi, additional, Katagiri, Atsushi, additional, Yamanouchi, Takenori, additional, Kiyokawa, Hirofumi, additional, Kawakubo, Hirofumi, additional, Konno, Maki, additional, Yokoyama, Akira, additional, Ohashi, Shinya, additional, Kondo, Yuki, additional, Kishimoto, Yo, additional, Kano, Koichi, additional, Mure, Kanae, additional, Hayashi, Ryuichi, additional, Ishikawa, Hideki, additional, and Muto, Manabu, additional

Published
2023
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26. Clinical significance of gastrointestinal bleeding history in patients who undergo left atrial appendage closure.

Author

Kikuchi, Tatsuya, Kono, Yoshiyasu, Nakagawa, Koji, Okada, Hiroyuki, Miyamoto, Masakazu, Takaya, Yoichi, Hirata, Shoichiro, Inoo, Shoko, Kuraoka, Sakiko, Okanoue, Shotaro, Matsueda, Katsunori, Satomi, Takuya, Hamada, Kenta, Iwamuro, Masaya, Kawano, Seiji, and Kawahara, Yoshiro

Subjects
LEFT atrial appendage closure, GASTROINTESTINAL hemorrhage
Abstract

Background and Aim: Anticoagulant users with nonvalvular atrial fibrillation (NVAF) sometimes suffer from gastrointestinal bleeding (GIB) and have difficulty continuing the medication. Left atrial appendage closure (LAAC) has been developed for such situations. We aimed to clarify the clinical significance of a history of GIB in comparison to other factors in patients who had undergone LAAC. Methods: From October 2019 to September 2023, patients with NVAF who underwent LAAC at our hospital were enrolled. We investigated the percentage of patients with a history of GIB who underwent LAAC and compared the incidence of post‐LAAC bleeding in these patients compared to those with other factors. Results: A total of 45 patients were included. There were 19 patients (42%) with a history of GIB who underwent LAAC. In a Kaplan–Meier analysis, the cumulative incidence of bleeding complications after LAAC was significantly higher in patients with a history of GIB in comparison to patients with other factors. There were eight cases of post‐LAAC bleeding in total, and seven cases had GIB. Conclusions: We need to recognize that GIB is a significant complication in patients who undergo LAAC. The management of GIB by gastroenterologists is essential to the success of LAAC. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Review of oral and pharyngolaryngeal benign lesions detected during esophagogastroduodenoscopy

Author

Iwamuro, Masaya, Hamada, Kenta, Kawano, Seiji, Kawahara, Yoshiro, Otsuka, Motoyuki, Iwamuro, Masaya, Hamada, Kenta, Kawano, Seiji, Kawahara, Yoshiro, and Otsuka, Motoyuki

Abstract

Recent advancements in endoscopy equipment have facilitated endoscopists’ detection of neoplasms in the oral cavity and pharyngolaryngeal regions. In particular, image-enhanced endoscopy using narrow band imaging or blue laser imaging play an integral role in the endoscopic diagnosis of oral and pharyngolaryngeal cancers. Despite these advancements, limited studies have focused on benign lesions that can be observed during esophagogastroduodenoscopy in the oral and pharyngolaryngeal regions. Therefore, this mini-review aimed to provide essential information on such benign lesions, along with representative endoscopic images of dental caries, cleft palate, palatal torus, bifid uvula, compression by cervical osteophytes, tonsil hyperplasia, black hairy tongue, oral candidiasis, oral and pharyngolaryngeal ulcers, pharyngeal melanosis, oral tattoos associated with dental alloys, retention cysts, papilloma, radiation-induced changes, skin flaps, vocal cord paresis, and vocal fold leukoplakia. Whilst it is imperative to seek consultation from otolaryngologists or dentists in instances where the diagnosis cannot be definitively ascertained by endoscopists, the merits of attaining foundational expertise pertaining to oral and pharyngolaryngeal lesions are unequivocal. This article will be a valuable resource for endoscopists seeking to enhance their understanding of oral and pharyngolaryngeal lesions.

Published
2023

29. Clinicopathological Characteristics of Superficial Barrett's Adenocarcinoma in a Japanese Population: A Retrospective, Multicenter Study

Author

Hamada, Kenta, Kanzaki, Hiromitsu, Miyahara, Koji, Nakagawa, Masahiro, Mouri, Hirokazu, Mizuno, Motowo, Takahashi, Sakuma, Hori, Shinichiro, Nasu, Junichiro, Tsuzuki, Takao, Miyaike, Jiro, Takenaka, Ryuta, Yamauchi, Kenji, Kobayashi, Sayo, Toyokawa, Tatsuya, Inoue, Masafumi, Nishimura, Mamoru, Matsubara, Minoru, Tomoda, Jun, Yamasaki, Yasushi, Tanaka, Takehiro, Shirakawa, Yasuhiro, Kawahara, Yoshiro, Fujiwara, Toshiyoshi, Okada, Hiroyuki, and Okayama Gut Study Group

Subjects
Barrett's adenocarcinoma, lesion, surgery, Barrett Esophagus, endoscopic resection, Esophageal Neoplasms, Japan, short -segment Barrett's esophagus, metachronous, Humans, Adenocarcinoma, Retrospective Studies, long -segment Barrett's esophagus
Abstract

Objective Although Barrett's adenocarcinoma (BA) remains a minor disease in Japan, its incidence has been gradually increasing. We analyzed the characteristics of BA in Japanese populations. Methods We retrospectively reviewed medical records and analyzed the clinicopathological differences between short-segment Barrett's esophagus (SSBE) and long-segment Barrett's esophagus (LSBE), as well as metastasis. Local recurrence and metachronous lesions were analyzed only in patients who underwent endoscopic resection (ER). Patients Consecutive patients who had pathological T1 BAs resected by ER or surgery from January 2003 Results A total of 168 patients were analyzed, including 139 with SSBE and 29 with LSBE. In total, 67% of the SSBE lesions and 32% of the LSBE lesions were located between 0 and 3 o'clock (p=0.0014). No patients who achieved pathological margin-free resection (pR0) and 17% of patients who did not achieve pR0 experienced local recurrence (p=0.0131). None of the patients without lymphovascular involvement, a poorly differentiated component, lesion size of >30 mm, and submucosal invasion of >500 mu m experienced metastasis. The 5-year cumulative incidence rate of metachronous BA after ER was 0% in patients with SSBE and 40% in patients with LSBE (p=0.0005). Conclusion Superficial BA was likely to be detected at the right anterior wall of SSBE in the Japanese population. The risk for metachronous BA after ER was high in Japanese patients with LSBE, as in Western patients.

Published
2022

30. Risk factors for the development of second primary esophageal squamous-cell carcinoma after endoscopic resection for esophageal squamous-cell carcinoma according to genetic polymorphisms related to alcohol and nicotine metabolism.

Author

Katada, Chikatoshi, Yokoyama, Tetsuji, Mure, Kanae, Doyama, Hisashi, Nakanishi, Hiroyoshi, Shimizu, Yuichi, Yamamoto, Keiko, Furue, Yasuaki, Tamaoki, Masashi, Koike, Tomoyuki, Kawahara, Yoshiro, Kiyokawa, Hirofumi, Konno, Maki, Yokoyama, Akira, Ohashi, Shinya, Ishikawa, Hideki, and Muto, Manabu

Published
2023
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31. Degree of pharyngeal deformation caused by pharyngeal endoscopic submucosal dissection is associated with the incidence of aspiration pneumonia

Author

Abe, Makoto, additional, Kawahara, Yoshiro, additional, Obayashi, Yuka, additional, Baba, Yuki, additional, Hamada, Kenta, additional, Sakae, Hiroyuki, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitu, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Makino, Takuma, additional, Noda, Yohei, additional, Marunaka, Hidenori, additional, and Okada, Hiroyuki, additional

Published
2023
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32. Long-term Survival After Endoscopic Resection For Gastric Cancer: Real-world Evidence From a Multicenter Prospective Cohort

Author

Suzuki, Haruhisa, primary, Ono, Hiroyuki, additional, Hirasawa, Toshiaki, additional, Takeuchi, Yoji, additional, Ishido, Kenji, additional, Hoteya, Shu, additional, Yano, Tomonori, additional, Tanaka, Shinji, additional, Toya, Yosuke, additional, Nakagawa, Masahiro, additional, Toyonaga, Takashi, additional, Takemura, Kenichi, additional, Hirasawa, Kingo, additional, Matsuda, Mitsuru, additional, Yamamoto, Hironori, additional, Tsuji, Yosuke, additional, Hashimoto, Satoru, additional, Yuki, Maeda, additional, Oyama, Tsuneo, additional, Takenaka, Ryuta, additional, Yamamoto, Yoshinobu, additional, Naito, Yuji, additional, Yamamoto, Katsumi, additional, Kobayashi, Nozomu, additional, Kawahara, Yoshiro, additional, Hirano, Masaaki, additional, Koizumi, Shigeto, additional, Hori, Shinichiro, additional, Tajika, Masahiro, additional, Hikichi, Takuto, additional, Yao, Kenshi, additional, Yokoi, Chizu, additional, Ohnita, Ken, additional, Hisanaga, Yasuhiro, additional, Sumiyoshi, Tetsuya, additional, Kitamura, Shinji, additional, Tanaka, Hisao, additional, Shimoda, Ryo, additional, Shimazu, Taichi, additional, Takizawa, Kohei, additional, Tanabe, Satoshi, additional, Kondo, Hitoshi, additional, Iishi, Hiroyasu, additional, Ninomiya, Motoki, additional, Oda, Ichiro, additional, Mashimo, Yumi, additional, Ishigooka, Masahiro, additional, Fukase, Kazutoshi, additional, and Mizuguchi, Yasuhiko, additional

Published
2023
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37. Multicenter Prospective Study on the Safety of Upper Gastrointestinal Endoscopic Procedures in Antithrombotic Drug Users

Author

Kono, Yoshiyasu, Matsubara, Minoru, Toyokawa, Tatsuya, Takenaka, Ryuta, Suzuki, Seiyu, Nasu, Junichirou, Yoshioka, Masao, Nakagawa, Masahiro, Mizuno, Motowo, Sakae, Hiroyuki, Abe, Makoto, Gotoda, Tatsuhiro, Miura, Ko, Kanzaki, Hiromitsu, Iwamuro, Masaya, Hori, Keisuke, Tsuzuki, Takao, Kita, Masahide, Kawano, Seiji, Kawahara, Yoshiro, and Okada, Hiroyuki

Published
2017
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38. Efficacy and Safety of a Novel Hemostatic Peptide Solution During Endoscopic Submucosal Dissection: A Multicenter Randomized Controlled Trial

Author

Uraoka, Toshio, primary, Uedo, Noriya, additional, Oyama, Tsuneo, additional, Saito, Yutaka, additional, Yahagi, Naohisa, additional, Fujimoto, Ai, additional, Kawahara, Yoshiro, additional, Mabe, Katsuhiro, additional, Hikichi, Takuto, additional, Yamamoto, Yorimasa, additional, and Tajiri, Hisao, additional

Published
2022
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41. Postoperative Bleeding Risk after Gastric Endoscopic Submucosal Dissection in Patients Receiving a P2Y12 Receptor Antagonist

Author

Hirai, Ryosuke, primary, Kawano, Seiji, additional, Inoo, Shoko, additional, Kuraoka, Sakiko, additional, Okanoue, Shotaro, additional, Satomi, Takuya, additional, Hamada, Kenta, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Iwamuro, Masaya, additional, Kawahara, Yoshiro, additional, and Okada, Hiroyuki, additional

Published
2022
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43. Zinc Acetate Dihydrate Tablet-associated Gastric Lesions

Author

Iwamuro, Masaya, Tanaka, Takehiro, Kuraoka, Sakiko, Hamada, Kenta, Abe, Makoto, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Kawano, Seiji, Kawahara, Yoshiro, and Okada, Hiroyuki

Subjects
gastric erosion, gastric ulcer, zinc acetate dihydrate, esophagogastroduodenoscopy, Internal Medicine, Stomach Diseases, Zinc Acetate, Humans, General Medicine, Ulcer, Retrospective Studies, Tablets
Abstract

Objective This study aimed to determine the prevalence and endoscopic features of zinc acetate dihydrate tablet-associated gastric lesions. Methods We retrospectively examined the endoscopic features of 47 patients taking zinc acetate dihydrate tablets who underwent esophagogastroduodenoscopy. Results Gastric mucosal alterations, including redness, erosions, ulcers, and adhesion of the white coat, were observed in 29 of 47 patients (61.7%). Among patients with gastric lesions (group A), there was a sig-nificantly higher percentage of symptomatic patients in comparison to patients without lesions (group B) (65.5% vs. 22.2%; p Conclusion Gastric lesions were observed in 29 of 47 patients who were taking zinc acetate dihydrate tab-lets. The most common endoscopic findings were mucosal redness (93.1%), erosions (90.0%), adhesion of the white coat (86.2%), and ulcers (31.0%). Although the exact pathogenesis is uncertain, we believe that un-derstanding the unique manifestations of this gastric lesion will help physicians manage adverse events in pa-tients taking zinc acetate dihydrate tablets.

Published
2022

44. Site-specific differences in T lymphocyte composition of the gastric mucosa after Helicobacter pylori eradication

Author

Iwamuro, Masaya, primary, Takahashi, Takahide, additional, Watanabe, Natsuki, additional, Abe, Makoto, additional, Sakae, Hiroyuki, additional, Kono, Yoshiyasu, additional, Kanzaki, Hiromitsu, additional, Tanaka, Takehiro, additional, Kawano, Seiji, additional, Otsuka, Fumio, additional, Kawahara, Yoshiro, additional, Yanai, Hiroyuki, additional, and Okada, Hiroyuki, additional

Published
2022
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45. The diagnostic ability to classify neoplasias occurring in inflammatory bowel disease by artificial intelligence and endoscopists: A pilot study

Author

Yamamoto, Shumpei, primary, Kinugasa, Hideaki, additional, Hamada, Kenta, additional, Tomiya, Masahiro, additional, Tanimoto, Takayoshi, additional, Ohto, Akimitsu, additional, Toda, Akira, additional, Takei, Daisuke, additional, Matsubara, Minoru, additional, Suzuki, Seiyu, additional, Inoue, Kosuke, additional, Tanaka, Takehiro, additional, Hiraoka, Sakiko, additional, Okada, Hiroyuki, additional, and Kawahara, Yoshiro, additional

Published
2022
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46. A NEW HEMOSTATIC PEPTIDE SOLUTION FOR REDUCTION OF ELECTROCAUTERIZATION DURING ENDOSCOPIC SUBMUCOSAL DISSECTION: A MULTICENTER RANDOMIZED CONTROLLED TRIAL

Author

Uedo, Noriya, primary, Uraoka, Toshio, additional, Saito, Yutaka, additional, Oyama, Tsuneo, additional, Kawahara, Yoshiro, additional, Fujimoto, Ai, additional, Yahagi, Naohisa, additional, Mabe, Katsuhiro, additional, Hikichi, Takuto, additional, Yamamoto, Yorimasa, additional, and Tajiri, Hisao, additional

Published
2022
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47. Prospective multicenter study of the efficacy and safety of cold forceps polypectomy for ≤ 6-mm non-ampullary duodenal low-grade adenomas

Author

Kanzaki, Hiromitsu, additional, Horii, Joichiro, additional, Takenaka, Ryuta, additional, Nakagawa, Hiroyuki, additional, Matsueda, Kazuhiro, additional, Tsuzuki, Takao, additional, Kita, Masahide, additional, Yamasaki, Yasushi, additional, Tanaka, Takehiro, additional, Iwamuro, Masaya, additional, Kawano, Seiji, additional, Kawahara, Yoshiro, additional, Tomoda, Jun, additional, and Okada, Hiroyuki, additional

Published
2022
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48. A Novel Method for Detecting Lanthanum Phosphate Deposition in the Gastroduodenal Mucosa Using Fluorescence Microscopy

Author

Iwamuro, Masaya, Urata, Haruo, Iwasa, Satoshi, Tanaka, Takehiro, Kawahara, Yoshiro, Okada, Horoyuki, Iwamuro, Masaya, Urata, Haruo, Iwasa, Satoshi, Tanaka, Takehiro, Kawahara, Yoshiro, and Okada, Horoyuki

Abstract

Diagnostic utility of fluorescence microscopy for lanthanum phosphate deposition in the gastrointestinal mucosa has not been reported previously. In this study, we comparatively assessed the light, electron, and fluorescence microscopy features of gastroduodenal lanthanum phosphate deposition in 10 patients with deposits in the stomach and 5 patients with deposits in the duodenum. During light microscopy, lanthanum deposits were observed as dark-brown, needle-shaped, or crystalloid structures and pale red amorphous materials. During electron microscopy, the deposited material appeared as bright aggregates. Fluorescence microscopy also revealed lanthanum deposits as bright areas under green, red, and blue filters. The deposits were more easily recognizable on electron and fluorescence microscopy than on light microscopy. Furthermore, during fluorescence microscopy, the green filter provided the most clear visualization of lanthanum phosphate. In conclusion, fluorescence microscopy with a green filter is useful in determining the degree and extent of lanthanum deposition in the gastroduodenal mucosa.

Published
2022

49. Two Cases of Duodenal Ulcers That Developed after Transcatheter Procedures for Unruptured Visceral Artery Aneurysms

Author

Iwamuro, Masaya, Kawai, Yusuke, Uka, Mayu, Matsui, Yusuke, Hiraki, Takao, Kawahara, Yoshiro, Okada, Hiroyuki, Iwamuro, Masaya, Kawai, Yusuke, Uka, Mayu, Matsui, Yusuke, Hiraki, Takao, Kawahara, Yoshiro, and Okada, Hiroyuki

Abstract

Herein, we report two cases of duodenal ulcers that developed after transcatheter procedures for the treatment of unruptured artery aneurysms. Both patients recovered after the administration of nothing by mouth, intravenous fluids, and proton-pump inhibitors. Notably, the duodenal ulcer was unchanged in one patient six days after endovascular treatment and improved in the other patient 13 days after angiography. These cases suggest that conservative treatment is acceptable in patients with duodenal ischemia that develops as an adverse effect of endovascular procedures. The usefulness of esophagogastroduodenoscopy in such patients has also been highlighted.

Published
2022

50. Characterization of Gastric Tissue-Resident T Cells in Autoimmune and Helicobacter pylori-Associated Gastritis

Author

Kametaka, Daisuke, Iwamuro, Masaya, Takahashi, Takahide, Hirabata, Araki, Hamada, Kenta, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Kawano, Seiji, Tanaka, Takehiro, Otsuka, Fumio, Kawahara, Yoshiro, Okada, Hiroyuki, Kametaka, Daisuke, Iwamuro, Masaya, Takahashi, Takahide, Hirabata, Araki, Hamada, Kenta, Kono, Yoshiyasu, Kanzaki, Hiromitsu, Kawano, Seiji, Tanaka, Takehiro, Otsuka, Fumio, Kawahara, Yoshiro, and Okada, Hiroyuki

Abstract

Data regarding the in-depth surface marker profiles of gastric tissue-resident lymphocytes in autoimmune and Helicobacter pylori-associated gastritis are lacking. In this study, we investigated potential differences in lymphocyte composition between these profiles. We enrolled patients with autoimmune (n = 14), active (current infection of H. pylori in the stomach; n = 10), and inactive gastritis (post-eradication of H. pylori; n = 20). Lymphocytes were isolated from the greater curvature of the stomach and lesser curvature of the body and analyzed using flow cytometry. The CD8(+)/CD3(+) and CD4(+)/CD3(+) ratios differed between the samples. Body CD4(+)/antrum CD4(+), which is calculated by dividing the CD4(+)/CD3(+) ratio in the body by that in the antrum, was significantly higher in autoimmune gastritis (3.54 +/- 3.13) than in active (1.47 +/- 0.41) and inactive gastritis (1.42 +/- 0.77). Antrum CD8(+)/CD4(+) in autoimmune gastritis (7.86 +/- 7.23) was also higher than that in active (1.49 +/- 0.58) and inactive gastritis (2.84 +/- 2.17). The area under the receiver operating characteristic curve of antrum CD8(+)/CD4(+) was 0.842, and the corresponding optimal cutoff point was 4.0, with a sensitivity of 71.4% and a specificity of 93.3%. We propose that an antrum CD8(+)/CD4(+) ratio > 4.0 is a potential diagnostic marker for autoimmune gastritis.

Published
2022

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