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2. An optimised patient-derived explant platform for breast cancer reflects clinical responses to chemotherapy and antibody-directed therapy

Author

Demetriou, Constantinos, Abid, Naila, Butterworth, Michael, Lezina, Larissa, Sandhu, Pavandeep, Howells, Lynne, Powley, Ian R., Pringle, James H., Sidat, Zahirah, Qassid, Omar, Purnell, Dave, Kaushik, Monika, Duckworth, Kaitlin, Hartshorn, Helen, Thomas, Anne, Shaw, Jacqui A., MacFarlane, Marion, Pritchard, Catrin, and Miles, Gareth J.

Published
2024
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3. Bio-inspired Nanomaterials in Cancer Theranostics

Author

Kaushik, Monika, Kumar, Sanjesh, Singh, Mansi, Sharma, Himanshu, Bhowmick, Mithun, Bhowmick, Pratibha, Ashique, Sumel, Khatoon, Heya, Pal, Radheshyam, Ansari, Mohammad Azam, Barkat, Md. Abul, editor, Ahmad, Farhan Jalees, editor, Rahman, Mohammad Akhlaquer, editor, and Ansari, Mohammad Azam, editor

Published
2024
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5. Enhancing Sustainable Development Through Electrooculography Based Computer Control System for Individuals with Mobility Limitations

Author

Bhalla, Pragya, Tiwary, Diksha, Aggarwal, Manasvi, Sharma, Sakshi, Kaushik, Monika, Agarwal, Megha, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Whig, Pawan, editor, Silva, Nuno, editor, Elngar, Ahmed A., editor, Aneja, Nagender, editor, and Sharma, Pavika, editor

Published
2023
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6. Development of Third Eye for Enabling Sustainable Mobility for the Visually Impaired

Author

Mishra, Hrithik, Gupta, Dev, Jain, Trithesh, Saini, Pulkit, Kaushik, Monika, Agarwal, Megha, Filipe, Joaquim, Editorial Board Member, Ghosh, Ashish, Editorial Board Member, Prates, Raquel Oliveira, Editorial Board Member, Zhou, Lizhu, Editorial Board Member, Whig, Pawan, editor, Silva, Nuno, editor, Elngar, Ahmed A., editor, Aneja, Nagender, editor, and Sharma, Pavika, editor

Published
2023
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12. REQUITE: A prospective multicentre cohort study of patients undergoing radiotherapy for breast, lung or prostate cancer

Author

Lievens, Yolande, van Eijkeren, Marc, Vandecasteele, Katrien, Elhamin, Elhaseen, Ost, Piet, Fonteyne, Valérie, Swimberghe, Martijn, Deseyne, Pieter, De Neve, Wilfried, Duprez, Fréderic, Mareel, Marcus, Monten, Chris, Van Greveling, Annick, Vercauteren, Tom, Paelinck, Leen, Defraene, Gilles, Aerts, Rita, Arredouani, Soumia, Lambrecht, Maarten, Vanneste, Ben, Draghici, Roxana, Giordano, Frank, Herskind, Carsten, Veldwijk, Marlon, Helmbold, Irmgard, Giesche, Ulrich, Stegmaier, Petra, Weiß, Christian, Blaschke, Thomas, Neu, Burkhard, Lozza, Laura, Avuzzi, Barbara, Morlino, Sara, Sangalli, Claudia, Franceschini, Marzia, Rodriguez-Lage, Belina, Fernández-Tajes, Juan, Fuentes-Rios, Olivia, Domínguez-Rios, Isabel, Fajardo-Paneque, Irene, Sosa-Fajardo, Paloma, Torrado-Moya, Laura, Ramos-Albiac, Mónica, Giraldo, Alexandra, Altabas, Manolo, Piqué-Leiva, Bibiana, García-Relancio, David, Seoane-Ramallo, Alejandro, Lavers, Samuel, Wright, Simon, Dobbelaere, Hannah, Appleton, Donna, Kaushik, Monika, Kenny, Frances, Khout, Hazem, Krupa, Jaroslaw, Lambert, Kelly V., Pilgrim, Simon, Shokuhi, Sheila, Valassiadou, Kalliope, Aznar-Garcia, Luis, Boiangui, Ion, Kancherla, Kiran, Kent, Christopher, Sampson, Kufre, Osman, Ahmed, Sridhar, Thiagarajan, Vasanthan, Subramaniam, Faivre-Finn, Corinne, Harrop, Victoria, Keni, Manjusha, Foweraker, Karen, Pascoe, Abigail, Esler, Claire, Stock, Richard, Green, Sheryl, Golchin, Ava, Li, William, Seibold, Petra, Webb, Adam, Aguado-Barrera, Miguel E., Azria, David, Bourgier, Celine, Brengues, Muriel, Briers, Erik, Bultijnck, Renée, Calvo-Crespo, Patricia, Carballo, Ana, Choudhury, Ananya, Cicchetti, Alessandro, Claßen, Johannes, Delmastro, Elena, Dunning, Alison M., Elliott, Rebecca M., Fachal, Laura, Farcy-Jacquet, Marie-Pierre, Gabriele, Pietro, Garibaldi, Elisabetta, Gómez-Caamaño, Antonio, Gutiérrez-Enríquez, Sara, Higginson, Daniel S., Johnson, Kerstie, Lobato-Busto, Ramón, Mollà, Meritxell, Müller, Anusha, Payne, Debbie, Peleteiro, Paula, Post, Giselle, Rancati, Tiziana, Rattay, Tim, Reyes, Victoria, Rosenstein, Barry S., De Ruysscher, Dirk, De Santis, Maria Carmen, Schäfer, Jörg, Schnabel, Thomas, Sperk, Elena, Symonds, R. Paul, Stobart, Hilary, Taboada-Valladares, Begoña, Talbot, Christopher J., Valdagni, Riccardo, Vega, Ana, Veldeman, Liv, Ward, Tim, Weißenberger, Christian, West, Catharine M.L., and Chang-Claude, Jenny

Published
2019
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13. Laparoscopic donor nephrectomy : evolution of technique and donor outcomes

Author

Kaushik, Monika and Nicholson, Michael

Subjects
616.6
Abstract

Background: The interest in living donor transplantation has been driven by the continuing fall in available cadaveric organs for transplantation. During the last five years there has been a substantial growth in living donor kidney transplantation in the UK but there is still considerable room for expansion in comparison with activity in Scandinavia and the USA. Traditionally kidneys have been harvested from donors via a loin incision with partial resection of the twelfth rib, which placed a considerable burden on the donors in terms of post-operative pain, absence from work, and morbidity. Laparoscopic live donor nephrectomy developed in 1995, promised to reduce these burdens on the donors and reduce some of the disincentives to kidney donation. Several comparative studies have shown this new technique to hold promise in terms of less pain and faster inpatient and outpatient recovery. However there were some concerns in procuring the kidneys with this technique, namely, increase in warm ischaemia times and the quality of graft. Methods: This was addressed in the setting of a prospective randomised controlled trial of laparoscopic versus limited incision live donor nephrectomy. Live kidney donors were randomly assigned in a 2:1 ratio to laparoscopic (LDN n=56) or short incision open donor nephrectomy (ODN n=28). Quality of life was assessed using the Short-Form 36 questionnaire. Postoperative analgesia was by morphine PCAS. Pain scores were recorded using visual analogue and verbal response scales. Donor convalescence was self-reported using a prospective diary system. Our study was the first randomised control trial to present live donor transplant recipient data at a minimum follow-up of four years. There were no differences in renal function or allograft survival for kidneys removed by LDN (laparoscopic donor nephrectomy) or ODN (open donor nephrectomy) at this point. The other aspect of this study is that this is the first study to compare respiratory function after LDN and ODN. During the evolution of LDN, the vessels are secured with various methods (endoclips, polymer clips and stapling device). These methods were compared with respect to complications and maximum length of vessels obtained. Technical modifications and improvement of techniques especially when comparing right and left donor nephrectomy are described. Results: Postoperative morphine requirement was lower in the LDN group [median (range) 59 (6-136) vs ODN 90 (35-312)mg; p=0.01]. Donors in the LDN group returned to normal activities more quickly compared to the ODN group [median (range) days to: driving 21 (7- 70) vs 28 (7-70); p=0.05), exercise 28 (7-77) vs 42 (14-84); p=0.001, return to work 42 (14- 84) vs 66.5 (14-112); p=0.001]. When compared to the pre-operative baseline, norm adjusted physical component scores (PCS) fell significantly at 6 weeks in both the LDN (mean±SD 46.3±8.9 vs 55±6.9; p=0.001) and ODN groups (44.0±7.9 vs 52.7±9.0; p=0.008). Nonetheless, the bodily pain domain score of PCS was significantly better in the LDN group (57.5 to 49.5; p=0.0001). The mental component score also fell in the ODN group (48±10.2 vs 53.5±7.6; p=0.02). In contrast, there was no fall in the mental component score after LDN (mean±SD 51.9±7.2 vs 53.8±6.4; p=0.29). Conclusions: In conclusion, our trial has shown that laparoscopic donor nephrectomy removes some of the disincentives to live kidney donation. This can be achieved without any additional morbidity in the recipient. This study provides high-level evidence to show that laparoscopic donor nephrectomy improves recovery back to the normal activities of daily life, is less painful than open surgery and improves the mental component of quality of life.

Published
2010

16. Role of miRNAs in Brain Development

Author

Sharma, Himanshu, Kaushik, Monika, Goswami, Priyanka, Sreevani, Sanakattula, Chakraborty, Ananya, Ashique, Sumel, and Pal, Radheshyam

Abstract

Non-coding RNAs that are small in size, called microRNAs (miRNAs), exert a consequence in neutralizing gene activity after transcription. The nervous system is a massively expressed organ, and an expanding body of research reveals the vital functions that miRNAs play in the brain's growth and neural activity. The significant benefit of miRNAs on the development of the central nervous system is currently shown through new scientific methods that concentrate on targeting and eradicating vital miRNA biogenesis pathways the elements involving Dicer and DGCR8. Modulation of miRNA has been associated with numerous essential cellular processes on neural progenitors, like differentiation, proliferation, and destiny determination. Current research discoveries that emphasize the significance of miRNAs in the complex process of brain development are included in this book. The miRNA pathway plays a major role in brain development, its operational dynamics, and even diseases. Recent studies on miRNA-mediated gene regulation within neural discrepancy, the circadian period and synaptic remodeling are signs of this. We also discussed how these discoveries may affect our comprehension of the fundamental processes behind brain diseases, highlighting the novel therapeutic opportunities miRNAs provide for treating various human illnesses.

Published
2024
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20. RP-HPLC method development and validation for simultaneous estimation of mesalamine and curcumin in bulk form as well as nanostructured lipid carriers

Author

Awasthi, Ankit, primary, Kumar, Ankit, additional, Kumar, Rajan, additional, Vishwas, Sukriti, additional, Khursheed, Rubiya, additional, Kaur, Jaskiran, additional, Corrie, Leander, additional, Kumar, Bimlesh, additional, Gulati, Monica, additional, Kumar, Deepak, additional, Kaushik, Monika, additional, Gupta, Gaurav, additional, Prasher, Parteek, additional, Chellappan, Dinesh Kumar, additional, Kumar, Avvaru Praveen, additional, Dua, Kamal, additional, and Singh, Sachin Kumar, additional

Published
2022
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21. Recent Progress in Development of Dressings Used for Diabetic Wounds with Special Emphasis on Scaffolds

Author

Awasthi, Ankit, primary, Gulati, Monica, additional, Kumar, Bimlesh, additional, Kaur, Jaskiran, additional, Vishwas, Sukriti, additional, Khursheed, Rubiya, additional, Porwal, Omji, additional, Alam, Aftab, additional, KR, Arya, additional, Corrie, Leander, additional, Kumar, Rajan, additional, Kumar, Ankit, additional, Kaushik, Monika, additional, Jha, Niraj Kumar, additional, Gupta, Piyush Kumar, additional, Chellappan, Dinesh Kumar, additional, Gupta, Gaurav, additional, Dua, Kamal, additional, Gupta, Saurabh, additional, Gundamaraju, Rohit, additional, Rao, Pasupuleti Visweswara, additional, and Singh, Sachin Kumar, additional

Published
2022
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23. tREPs─A New Class of Functional tRNA-Encoded Peptides

Author

Chakrabarti, Amrita, primary, Kaushik, Monika, additional, Khan, Juveria, additional, Soota, Deepanshu, additional, Ponnusamy, Kalairasan, additional, Saini, Sunil, additional, Manvati, Siddharth, additional, Singhal, Jhalak, additional, Ranganathan, Anand, additional, Pati, Soumya, additional, Dhar, Pawan Kumar, additional, and Singh, Shailja, additional

Published
2022
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25. Therapeutic mammoplasty is associated with fewer long-term side-effects from breast radiotherapy

Author

Brodie, Arjuna, primary, Gaber, Ahmed, additional, Kaushik, Monika, additional, Kenny, Frances, additional, Krupa, Jaroslaw, additional, Lambert, Kelly V., additional, Pilgrim, Simon M., additional, Sasi, Walid, additional, Shokuhi, Sheila, additional, Valassiadou, Kalliope, additional, Kancherla, Kiran, additional, Sampson, Kufre, additional, Talbot, Christopher J., additional, West, Catharine, additional, and Rattay, Tim, additional

Published
2022
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28. Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK ‘Alert Level 4’ phase of the B-MaP-C study

Author

Dave, Rajiv V., Kim, Baek, Courtney, Alona, O’Connell, Rachel, Rattay, Tim, Taxiarchi, Vicky P., Kirkham, Jamie J., Camacho, Elizabeth M., Fairbrother, Patricia, Sharma, Nisha, Cartlidge, Christopher W. J., Horgan, Kieran, McIntosh, Stuart A., Leff, Daniel R., Vidya, Raghavan, Holcombe, Chris, Copson, Ellen, Coles, Charlotte E., Cutress, Ramsey I., Gandhi, Ashu, Kirwan, Cliona C., Agrawal, Amit, Benson, John, Forouhi, Parto, Wignarajah, Primeera, Shrotri, Anu, Kattakayam, Arjun, Noronha, Jarin Louis, Martin, Lee, Lafi, Mohamed, Hardy, Rob, Amin, Khalid, AL-Zawi, Abdalla Saad Abdalla, Elamass, Mohamed, Salih, Ali, Alkistawi, Firas Eddin Bachir, Heeney, Anna, Hill, Arnold D. K., Power, Colm, Allen, Michael J., Chouhan, Ashok, Rathinaezhil, Rathi, Shaheed, Samy, Zammit, Charles, Clayton, Gillian, Dua, Sascha, Smith, Simon, Gandamihardja, Tasha, Williams, Chloe, Egbeare, Donna, Davies, Eleri, Sweetland, Helen M., Chopra, Sharat, Goyal, Sumit, Elfadl, Dalia, Rana, Dheer Singh, Kalakouti, Eliana, Barkeji, Musa, Vashisht, Rajiv, Bunza, Ralia, Phyu, Saung Hnin, Hollywood, Ciaran, Azmy, Iman, Massey, Julia, Hargreaves, Anita, Harding-Mackean, Claudia, Ooi, Jane, Seward, Joanna, Mathers, Helen, Scally, Norah, Salman, Reem, Shin, Hyunjin, Turner, Jane, Noor, Lubna, Joshi, Sanjay, Horne, Sarah, Sarakbi, Wail Al, Liptay-Wagner, Peter, Jacklin, Rosamond, Chandrasekharan, Sankaran, Marsh, Simon, Saha, Sunita, Wilson, Christopher, Rutherford, Claire Louise, Doughty, Julie, Romics, Laszlo, Stallard, Sheila, Chaudhry, Anushka, Peck, Jennifer, Coombs, Nathan, Williams, Samantha K., Hawkins, Simon, Kothari, Ashutosh, Hamed, Hisham, Jain, Urvashi, Daltrey, Ian, Abbott, Nick, Mullen, Russell, Dumitru, Dorin, Khalifa, Eiman, Sarker, Masuma, Elahi, M. Bilal, Bichoo, Raouef Ahmed, Gvaramadze, Anzors, Thekkinkattil, Dinesh, Jibril, Jibril, Hadjiminas, Demetrios, St John, Edward R. C., Robb, Henry Douglas, Hogben, Katy, Bakri, Nur Amalina Che, Thiruchelvam, Paul, Exarchos, Georgios, Al-Mufti, Ragheed, Mortimer, Caroline, Mallidis, Evangelos, Karagiannidis, Georgios, Tuffaha, Hussein, Peerlink, Inga, Nair, Rajive, Prusty, Lydia, Sami, Amtul, Knight, Alex, Ravichandran, Duraisamy, Kirkpatrick, Katharine, James, Ruth, Akolekar, Deepika, Mehta, Disha, Barua, Ellora, Knowles, Hannah, Devalia, Haresh, Cox, Karina, Dani, Mohsin, Chalmers, Ritchie, Satpathy, Anjana, Quinn, Edel, Byrne, Gerard, Harvey, James, Murphy, John, Highton, Lyndsey, Sharif, Mohammad Amir, Barnes, Nicola, Dimopoulos, Nikitas, Johnson, Richard, Chatterjee, Sumohan, Fatayer, Hiba, Mathen, Vinod, Taylor, Amanda, Soulsby, Rachel, Walsh, Adam, Thorne, Amanda, Gill, Jasper, Merker, Louise, Critchley, Adam, Pieri, Andrew, Cain, Henry, Ralph, Jane, Kalra, Loraine, Thomas, Robert, Young, Ian, Khan, Lucy R., Elsberger, Beatrix, Smyth, Elizabeth, Urquhart, Gordon, Fuller, Mairi, Masannat, Yazan, Chrysafi, Ada, Salman, Muhammad, Abdalla, El-Rasheed, Zechmeister, Katalin, Hussien, Maged, Youssef, Mina M. G., Tanhueco, Angeline, Salvador, Reginald, Wallace, Sharon, Pain, Simon, Sahu, Ajay, Chambers, Alice, Moody, Alice, Dash, Isabella, Cook, James, Batt, Jeremy, Mullan, Michelle, Shere, Mike, Gallegos, Nicholas, Ainsworth, Rachel, Govindarajulu, Sasi, Potter, Shelley, Rayter, Zenon, Williams, Kate E., Bramley, Maria, Absar, Mohammed, Nasir, Nabila, Tabbakh, Rami, Pereira, Bernadette, Gahir, Jasdeep, Bosch, Karen, Fafemi, Oladapo, Touqan, Nader, Oni, Georgette, Khout, Hazem, Asgeirsson, Kristjan, Whisker, Lisa, Lee, Rachel Xue Ning, Macmillan, Robert, McCulley, Stephen, Rasheed, Tuabin, Adwani, Asha, Segaran, Ashvina, Dodwell, David, Remoundos, Dennis, MacLean, Gael, Cuffolo, Giulio, Douek, Michael, Roy, Pankaj, Gathani, Toral, Najeeb, Erum, Simonca, Claudiu, Verroiotou, Maria, Ramzi, Sa’ed, Jenkins, Stephanie C., Gopalan, Vallipuran, Barker, Sarah, McGoldrick, Ciara, Irwin, Gareth W., Mallon, Peter, Sloan, Samantha A., Imran, Abbas, Mondani, Giuseppina, Brown, Iain, Abbas, Imran, Sulieman, Mona, Drew, Philip, King, Polly, English, Rachel Elizabeth, Sharma, Anita, Ives, Charlotte, Ferguson, Douglas, Boundouki, George, Bentley, James, Banks, Jenny, Dunn, Julie, Tillett, Rachel, Olsen, Sisse, Tansley, Anne, Sousa, Emma De, Mitchell, Geraldine, Whitehead, Ian, Henderson, Julia, Rowland, Matthew, Chandrashekar, Mysore, Eid, Raja, Clayton, Elizabeth, Pakzad, Farrokh, Horsnell, Jonathan D., Hague, Matthew, Partlett, Polly, Irvine, Tracey, Kallaway, Charlotte, Fairhurst, Katherine, Laban, Christiana, McIntosh, Jamie, Laurence, Nicola, Sutton, Richard, Sharma, Anup, Banerjee, Dibyesh, Betambeau, Nadine, Bezzaa, Sabrina, Bathla, Sonia, Ray, Atanu, Chagla, Leena, Kiernan, Tamara, Hogan, Brian, Navin, Channegowda, Macinnes, Emma, Turton, Philip, Achuthan, Raj, Kantola, Venla, Mckenzie, Shireen, Dent, Helen, Pogson, Caroline, Waheed, Shamaela, De Silva, Tania S., Suleiman, Usama, Jones, Lucie, Athwal, Ruvinder, Harries, Simon, Krzyzanowska, Catherine, Abbas, Abeera, Hurley, Anna R., Gui, Gerald, Rusby, Jennifer E., Krupa, Katherine, Harborough, Kathryn E., Roche, Nicola, Barry, Peter A., Law, Rebekah, Allum, William H., Lobo, Cheryl, Ntakomyti, Eleni, Franks, Joanna, Cariati, Massimiliano, Patani, Neill, Stanilov, Noyko, Charalampoudis, Petros, Taraki, Zarghuna, McEvoy, Kat, Sait, Mohamed Razick, Robertson, Stuart, Zeidan, Bashar, Rew, David, Mazari, Fayyaz, Alder, Louise, Sakellariou, Vasileios, Hamad, Ahmed, Goyal, Amit, Carmichael, Amtul, Courtney, Carol-Ann, Sibbering, David Mark, Garreffa, Emanuele, Cheung, Kwok-Leung, Williams-Jones, Susan, Wahedna, Yasmin, Ansari, Aonghus, Kenny, Frances, Valassiadou, Kalliope, Lambert, Kelly, Krupa, Jaroslaw, Sardar, Mini V., Kaushik, Monika, Shokuhi, Sheila, Pilgrm, Simon, Sasi, Walid, McManus, Penelope, Parmeshwar, Rishikesh, Somasundaram, Santosh, Gowda, Manoj, Jafferbhoy, Sadaf, Narayanan, Sankaran, Marla, Sekhar, Soumian, Soni, Goh, Ngee-Ming, Vatish, Jamie, Sein, Tin Aung, Agabiti, Ennio, Maalo, Joseph, Chong, Kelvin, Lai, Lee-Min, Elkorety, Mohamed, Monib, Sherif, Thomson, Simon, Mikhael, Youhana, Mirshekar-Syahkal, Bahar, Aitken, Jane, Girgis, Mina, Betal, Dibendu, Rapisarda, Fabio, Cook, Lorna, Odofin, Olubunmi, Bonomi, Riccardo, Wardle, Stacy, Sotheran, Wendy, Athanasiou, Irene, Lund, Jonathan, Callaghan, Maria, Burrah, Rajaram, Vinayagam, Raman, James, Karen, Poonawala, Shabbir, Isgar, Brian, Matey, Pilar, Mylvaganam, Senthurun, Podesta, Carl, Sircar, Tapan, Salem, Fathi, Al-Ishaq, Zaid, Dave, Rajiv V. [0000-0001-6827-8090], McIntosh, Stuart A. [0000-0002-4123-9611], Potter, Shelley [0000-0002-6977-312X], Copson, Ellen [0000-0001-8994-4056], and Apollo - University of Cambridge Repository

Subjects
692/700/784, article, 692/4028/67/1347, 692/700/3934, 692/700/1538, 692/4028/546
Abstract

Background: The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions. Methods: This was a national cohort study of patients with early BC undergoing multidisciplinary team (MDT)-guided treatment recommendations during the pandemic, designated ‘standard’ or ‘COVID-altered’, in the preoperative, operative and post-operative setting. Findings: Of 3776 patients (from 64 UK units) in the study, 2246 (59%) had ‘COVID-altered’ management. ‘Bridging’ endocrine therapy was used (n = 951) where theatre capacity was reduced. There was increasing access to COVID-19 low-risk theatres during the study period (59%). In line with national guidance, immediate breast reconstruction was avoided (n = 299). Where adjuvant chemotherapy was omitted (n = 81), the median benefit was only 3% (IQR 2–9%) using ‘NHS Predict’. There was the rapid adoption of new evidence-based hypofractionated radiotherapy (n = 781, from 46 units). Only 14 patients (1%) tested positive for SARS-CoV-2 during their treatment journey. Conclusions: The majority of ‘COVID-altered’ management decisions were largely in line with pre-COVID evidence-based guidelines, implying that breast cancer survival outcomes are unlikely to be negatively impacted by the pandemic. However, in this study, the potential impact of delays to BC presentation or diagnosis remains unknown.

Published
2021
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32. 24. Partial breast reconstruction with chest wall perforator flaps - Initial data from 'partbrerecon' collaborative

Author

Agrawal, Amit, primary, Romics, Laszlo, additional, Thekkinkattil, Dinesh, additional, Kaushik, Monika, additional, Mortimer, Caroline, additional, Courtney, Carol-Ann, additional, Goyal, Amit, additional, Garreffa, Emanuele, additional, Carmichael, Amtul, additional, Hamad, Ahmed, additional, Lane, Risha, additional, Blackhall, Vivienne, additional, Rutherford, Claire, additional, Pitsinis, Vasileios, additional, Goh, Steven, additional, Ray, Biswajit, additional, Grover, Kartikae, additional, Mansell, James, additional, Vidya, Raghavan, additional, and Murphy, John, additional

Published
2021
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39. RelB suppresses type I Interferon signaling in dendritic cells

Author

Saha, Irene, primary, Jaiswal, Hemant, additional, Mishra, Richa, additional, Nel, Hendrik J., additional, Schreuder, Jaring, additional, Kaushik, Monika, additional, Singh Chauhan, Kuldeep, additional, Singh Rawat, Bhupendra, additional, Thomas, Ranjeny, additional, Naik, Shalin, additional, Kumar, Himanshu, additional, and Tailor, Prafullakumar, additional

Published
2020
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40. Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction

Author

Potter, S, primary, Trickey, A, additional, Rattay, T, additional, O'Connell, R L, additional, Dave, R, additional, Baker, E, additional, Whisker, L, additional, Skillman, J, additional, Gardiner, M D, additional, Macmillan, R D, additional, Holcombe, C, additional, Potter, S, additional, Barnes, Nicola L P, additional, Blazeby, Jane, additional, Conroy, Elizabeth, additional, Dave, Rajiv V, additional, Gardiner, Matthew D, additional, Harnett, Adrian, additional, Holcombe, Chris, additional, Potter, Shelley, additional, Rattay, Tim, additional, Skillman, Joanna, additional, Williamson, Paula, additional, Achuthan, Rajgopal, additional, Aggarwal, Shweta, additional, Baker, Elizabeth, additional, Basu, Naren, additional, Brock, Lisa, additional, Fairbrother, Patricia, additional, Ives, Charlotte, additional, Jain, Abhilash, additional, Kim, Baek, additional, Macmillan, R Douglas, additional, Murphy, John, additional, Remoundos, Dennis, additional, Sutton, Richard, additional, Trickey, Adam, additional, Turton, Philip, additional, Williams, Kathryn, additional, Curnier, Alain, additional, Tadros, Amir, additional, Depasquale, Ivan, additional, Fuller, Mairi, additional, Bourne, Roger, additional, Heys, Steven, additional, Hamo, Ishrak, additional, Aloraifi, Fatima, additional, Fopp, Laura, additional, Bali, Radhika, additional, Bache, Sarah, additional, Benyon, Sarah L, additional, Irwin, Michael S, additional, Agrawal, Amit, additional, Malata, Charles M, additional, Murphy, Claire, additional, Misky, Adam, additional, Chicken, Dennis Wayne, additional, Abdullah, Nassreen, additional, Hill, Arnold D K, additional, Cullinane, Carolyn, additional, Irwin, Gareth, additional, McIntosh, Stuart A, additional, Refsum, Sigi, additional, Sloan, Samantha, additional, Mallon, Peter, additional, Sirianni, Chiara, additional, Khattak, Ilyas, additional, Nagachandra, Geerthan, additional, Kiruparan, Pasupathy, additional, Debanth, Debasish, additional, Davey, Simon, additional, Curran, Terry-Ann, additional, Svenning, Matilda, additional, Govindarajulu, Sasirekha, additional, Rayter, Zenon, additional, Ainsworth, Rachel, additional, Cawthorn, Simon, additional, Sahu, Ajay, additional, Wilson, Sherif, additional, Prousskaia, Elena, additional, Accurso, Antonello, additional, Rocco, Nicola, additional, Di Micco, Rosa, additional, Limite, Gennaro, additional, Ceccarino, Raffaele, additional, Liccardo, Raffaele, additional, Coco, Guido, additional, Nizamoglu, Metin, additional, Morgan, Mary, additional, Ramakrishnan, Venkat, additional, Catanuto, Giuseppe, additional, Wilkins, Alex, additional, McManus, Penelope, additional, Kneeshaw, Peter, additional, Grover, Kartikae, additional, Mahapatra, Tapan, additional, Wooler, Brendan, additional, Elahi, Bilal, additional, Ihsan, Naila, additional, Bucknor, Alexandra, additional, Reissis, Dimitris, additional, Hunter, Judith, additional, Wood, Simon, additional, Jallali, Navid, additional, Henry, Francis P, additional, Verjee, Liaquat S, additional, Lee, Jason, additional, Khan, Shazia M, additional, Azmy, Iman, additional, Massey, Julia, additional, Hollywood, Ciaran, additional, Oluwajana, Michael, additional, Bathla, Sonia, additional, Seward, Joanna, additional, Harding-MacKean, Claudia, additional, Lane, Risha, additional, Murali, Kothandaraman, additional, Biswas, Bashishta, additional, Trapszo, Pawel, additional, Seetharam, Seema, additional, Kennedy, Katy, additional, Alder, Louise, additional, Graja, Tomasz, additional, Amin, Khalid, additional, Kokan, Jalal, additional, Roshanlall, Chandeena, additional, Gill, Emma, additional, Kulkarni, Dhananjay, additional, Dixon, J M, additional, Young, Oliver, additional, Saleem, Talha, additional, Biddle, M, additional, Kearns, Marie, additional, Weiler-Mithoff, Eva, additional, Chew, Ben, additional, Malyon, Andy, additional, Scott, John, additional, McGill, David, additional, Mackay, Iain, additional, Bains, Salena, additional, Barrows, Sara, additional, Pilgrim, Simon, additional, Shokuhi, Sheila, additional, Lambert, Kelly, additional, Kenny, Frances, additional, Valassiadou, Kalliope, additional, Kaushik, Monika, additional, Krupa, Jaroslaw, additional, Dragoumis, Dimitris, additional, Lampropoulos, Pavlos, additional, Moss, Sarah, additional, Khalil, Haitham, additional, Haq, Anwar, additional, Balasubramanian, Balapathiran, additional, Charalampoudis, Petros, additional, Hamed, Hisham, additional, Kothari, Ashutosh, additional, Kovacs, Tibor, additional, Douek, Michael, additional, Mehmood, Iftikhar, additional, Ray, Biswajit, additional, Adelekan, Matthew, additional, Humphreys, Laura, additional, Tayeh, Salim, additional, Choy, Christina, additional, Parvanta, Laila, additional, Michieletto, Silvia, additional, Saibene, Tania, additional, O'Brien, James, additional, Down, Sue, additional, Downey, Sarah, additional, Pereira, Jerome, additional, Sami, A S, additional, Gvaramadze, Anzors, additional, Jibril, Jibril A, additional, Thekkinkattil, Dinesh, additional, Udayasankar, S, additional, Khawaja, Saira, additional, Shariaha, Yousef, additional, Holt, Simon, additional, James, Ruth, additional, Rizki, Hirah, additional, Kirkpatrick, Katharine, additional, Ravichandran, Duraisamy, additional, Shrestha, Deepak, additional, Barua, Ellora, additional, Akolekar, Deepika, additional, Hamad, Ahmed, additional, Kleidi, Eleftheria, additional, Hignett, Susan, additional, Pope, Vanessa, additional, Naseem, Salma, additional, Isherwood, Jennifer, additional, Soulsby, Rachel, additional, Taylor, Amanda, additional, Chin, Kian, additional, Nguyen, Dai, additional, Guest, Francesca, additional, Thorne, Amanda, additional, Lefemine, Valentina, additional, Kirchhoff, Chris, additional, Murphy, Declan C, additional, Lo, Michelle, additional, Harcourt, Ruth, additional, Pain, Simon J, additional, Hussien, Maged I, additional, Zechmeister, Katalin, additional, Sassoon, E M, additional, Figus, Andrea, additional, Haywood, Richard M, additional, Ali, Rozina, additional, Alexander, Susanna, additional, Geropantas, Konstantinos, additional, Epurescu, Daniel, additional, Lewis, Rebecca, additional, Fafemi, Oladapo, additional, Gahir, Jasdeep, additional, Gandamihardja, Tasha, additional, Kelsall, Jennett, additional, Muhibullah, Nazli, additional, Otieno, Charlene, additional, Mazari, Fayyaz, additional, Dauria, Marta, additional, Whisker, Lisa, additional, Macmillan, Douglas, additional, Gutteridge, Eleanor, additional, Rasheed, Tuabin, additional, Khout, Hazem, additional, Asgeirsson, Kristjan, additional, McCulley, Stephen, additional, Mariniello, Maria Donatella, additional, Roncella, Manuela, additional, Ghilli, Matteo, additional, Colizzi, Livio, additional, Rossetti, Elena, additional, Marzia, Lo Russo, additional, Fustaino, Loredana, additional, Li, Alessandro Quattrini, additional, Harvey, Kate L, additional, Windle, Rebecca, additional, Remoundos, Dionysios Dennis, additional, Roy, Pankaj, additional, MacLean, Gael, additional, Adwani, Asha, additional, Popa, Elena, additional, Goh, Steven, additional, Shetty, Geeta, additional, Clark, Sarah, additional, Bernaudo, Lorenzo, additional, Agrawal, Avi, additional, Mansfield, Lucy, additional, Tebbal, Sally, additional, Patel, Ashraf, additional, Grassi, Veronica, additional, Pujji, Ojas, additional, Hamnett, Kathryn, additional, Granger, Emily, additional, Durbar, Michael, additional, Pikoulas, Panagiotis, additional, Garnsey, Clare, additional, Walker, Philip, additional, Vollermere, Angela J, additional, Michalakis, Ioannis, additional, Jones, Robin, additional, Youssef, Mina, additional, Masood, Mohammad, additional, Dunn, Julie, additional, Olsen, Sisse, additional, Ferguson, Douglas, additional, Tillett, Rachel, additional, Allan, Anna, additional, Woollard, Alex, additional, Canny, Rebecca, additional, Woollard, Alexander, additional, Mosahebi, Afshin, additional, Hamilton, Stephen, additional, Chana, Jagdeep, additional, Sojitra, Nilesh, additional, Younis, Ibby, additional, Rainsbury, Dick, additional, Chand, Natalie, additional, Kalles, Vasileios, additional, Stebbing, Anne, additional, Harris, Kevin, additional, Laws, Siobhan, additional, Tansley, Anne, additional, Mitchell, Geraldine, additional, de Sousa, Emma, additional, Henderson, Julia, additional, Chandrashekar, Mysore, additional, Pereira, Bernadette, additional, Constantinou, Chloe, additional, Elfadl, Dalia, additional, Irakleidis, Foivos, additional, Hernan, Izaro, additional, Byrne, Miriam, additional, O'Connell, Rachel, additional, Rusby, Jennifer, additional, Barry, Peter, additional, Krupa, Katerine, additional, Allum, William, additional, MacNeill, Fiona, additional, Roche, Nicola, additional, Gui, Gerald, additional, Ramsey, Kelvin, additional, Harris, Paul, additional, James, Stuart, additional, McIntosh, Jamie, additional, Laurence, Nicola, additional, MacLennan, Louise, additional, Milligan, Robert, additional, Cain, Henry, additional, Critchley, Adam, additional, O'Donoghue, Joe, additional, Kalra, Loraine, additional, Collis, Nick, additional, Weston-Petrides, Gina, additional, Fiddes, Roanne, additional, Brown, Victoria, additional, Aertssen, Anna, additional, Slade-Sharman, Diana, additional, Khan, Mansoor, additional, McGuiness, Caroline, additional, Amorosi, Vittoria, additional, di Pompeo Fabio, Santanelli, additional, Exarchos, Georgios, additional, Jiwa, Natasha, additional, Hu, Jennifer, additional, Ledwidge, Serena, additional, Johnson, Laura, additional, Peel, Anthony, additional, Dhooma, Naseem, additional, Farrell, Eric, additional, Devane, Liam, additional, Tevlin, Ruth, additional, McDermott, Enda, additional, Prichard, Ruth, additional, Evoy, Denis, additional, Rothwell, Jane, additional, Geraghty, James, additional, Morrison, Colin, additional, Lawlor, Catriona, additional, Langlands, Fiona, additional, Taylor, Lauren, additional, Achuthan, Raj, additional, Horgan, Kieran, additional, Mckenzie, Shireen, additional, Hogan, Brian, additional, Lansdown, Mark, additional, Navin, Channegowda, additional, Sherwin, Liz, additional, Mortimer, Caroline, additional, Garg, Neeraj, additional, Adam, Rahma, additional, Arif, Tahera, additional, Kryjak, Zbigniew, additional, Ali, Deedar, additional, Sowdi, Ravi, additional, Fage, Elena, additional, Mylvaganam, Senthurun, additional, Matey, Pilar, additional, Vidya, Raghavan, additional, Sircar, Tapan, additional, Asaad, Oubida, additional, Bhaskar, Pud, additional, Dordea, Matei, additional, Chrysafi, Ada, additional, McCartan, Damian, additional, Dave, Rajiv, additional, Foster, Rachel, additional, Wilson, Rebecca, additional, Okwemba, Sylvia, additional, Majeed, Yousef, additional, O'Brien, Ciara, additional, Mathen, Vinod, additional, Barnes, Nicola, additional, Gandhi, Ashu, additional, Harvey, James, additional, Kirwan, Cliona C, additional, Johnson, Richard, additional, Patel, Krupali, additional, Ribas, Maria Dalmau, additional, Vigneswaran, Natali, additional, Challoner, Tom, additional, Park, Alan, additional, Rizkalla, Maged, additional, Tomlins, Abigail, additional, McEvoy, Kat, additional, Jafferbhoy, Sadaf, additional, Soumian, Soni, additional, Narayanan, Sankaran, additional, Kirby, Robert, additional, Bajrusevic, Sladana, additional, Maalo, Joseph, additional, Charalambous, Michalis, additional, Lai, Lee Min, additional, Chong, Kelvin, additional, Thomson, Simon, additional, Monib, Sherif, additional, Chagla, Leena, additional, Audisio, Riccardo, additional, Taghizadeh, Rieka, additional, Iqbal, Azhar, additional, James, Karen, additional, Callaghan, Maria, additional, Poonawala, Shabbir, additional, Lund, Jonathan, additional, Vinayagam, Raman, additional, Thrush, Steven, additional, Thomas, Rachel Bright, additional, Mullan, Michelle, additional, Taylor, Jevan, additional, Yoshimura, Ryo, additional, Mathew, Tom, additional, Jones, Ben Mancey, additional, Munot, Kailas, additional, Nasr, Rana, additional, Piper, Jenny, additional, El-Sharief, Deena, additional, Mustafa, Mohammed, additional, MacLeod, Caitlin, additional, Smyth, Elizabeth, additional, Saeed, Nina, additional, Masannat, Yazan, additional, Mohd-Amin, Amir Tan, additional, Sloan, Sam, additional, McIntosh, Stuart, additional, Ibrahim, Abdulla, additional, Rathinaezhil, Rathi, additional, Khalifa, Eiman, additional, McManus, Penny, additional, Leeper, Alexander, additional, McIlhenny, Jennifer, additional, Mansell, James, additional, Ogsto, Keith, additional, Romics, Laszlo, additional, Shokuhi, Shelia, additional, Lee, Xiang Wei Jonathan, additional, Al-Allak, Asmaa, additional, Fowler, Clare, additional, Massey, Eleanore, additional, Court, Fiona, additional, Hunt, Richard, additional, Vestey, Sarah, additional, Elgammal, Mohsen, additional, Noshirwani, Arish, additional, Arif, Tehera, additional, Syed, Farah H, additional, Safdar, Gazalla, additional, El-Abbar, Mohammed, additional, Hogg, Fiona, additional, McGee, Pauline, additional, Pitsinis, Vassilis, additional, Smith, Jenny, additional, Makkiyah, Sundus, additional, Mustafa, Syed, additional, Photiou, Dana, additional, Gutteridge, Ellie, additional, Oni, Georgette, additional, Hallam, Kelly, additional, Asgeirron, Kristjan, additional, D'Auria, Marta, additional, Al-zubaidi, Samim, additional, Bailey, James, additional, Tenovici, Alexandra, additional, Remoundos, Dionysios-Dennis, additional, Chaidos, Nikos, additional, Predescu, Oana, additional, Rezulski, Jan, additional, Abdullah, Tholkifl, additional, Udayasankar, Sujatha, additional, Talbot, Adam, additional, Singh, Jagdeep, additional, Smith, Amy, additional, Volleamere, Angela, additional, Dean, Sarah, additional, Peiris, Lashan, additional, Sjokvist, Olivia, additional, De Sousa, Emma, additional, Micha, Aikaterini, additional, Godden, Amy, additional, Krupa, Katherine, additional, Henton, John, additional, Bennett, Ruth, additional, Nicholson, Stewart, additional, Paolini, Guido, additional, Renzi, Luca Francesco, additional, Di Pompeo, Santanelli, additional, Ria, Vitto, additional, Lewis, Rebecca S, additional, Hadad, Sirwan, additional, Sharma, Anup, additional, Toomey, Delia, additional, Banerjee, Dibyesh, additional, Tang, Sarah Shuk Kay, additional, McKenzie, Shireen, additional, Ahmad, Tanvir, additional, Williams, Kate, additional, Absar, Mohammed, additional, Nasir, Nabila, additional, Rychlik, Igor Jerzy, additional, Darragh, Lynn, additional, Johnston, Ruth, additional, Kirk, Stephen, additional, Rees-Lee, Jacqueline, additional, Green, Michael, additional, Sharma, Abhishek, additional, Choong, Jia, additional, Ullah, Zaker, additional, Koshy, Ommen, additional, Kiernan, Tamara, additional, Bhojwani, Ajay Ashok, additional, Bright-Thomas, Rachel, additional, Byrne, Ged, additional, Ibrahim, Ibrahim, additional, Highton, Lyndsey, additional, Morris, Owen, additional, Chatterjee, Sumohan, additional, Kirwan, Cliona, additional, Mancey-Jones, Ben, additional, El Sharief, Denna, additional, and Frame, Richard, additional

Published
2020
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42. The impact of immediate breast reconstruction on the time to delivery of adjuvant therapy: the iBRA-2 study

Author

O'Connell, Rachel L, Rattay, Tim, Dave, Rajiv V, Trickey, Adam, Skillman, Joanna, Barnes, Nicola LP, Gardiner, Matthew, Harnett, Adrian, Potter, Shelley, Holcombe, Chris, Blazeby, Jane, Conroy, Elizabeth, O'Brien, Ciara, Williamson, Paula, Curnier, Alain, Tadros, Amir, Depasquale, Ivan, Masannat, Yazan A, Smyth, Elizabeth, Fuller, Mairi, Bourne, Roger, Heys, Steven, Hamo, Ishrak, Aloraifi, Fatima, Fopp, Laura, Bali, Radhika, Bache, Sarah, Benyon, Sarah L, Irwin, Michael S, Agrawal, Amit, Malata, Charles M, Murphy, Claire, Misky, Adam, Chicken, Dennis Wayne, Abdullah, Nassreen, Hill, Arnold DK, Cullinane, Carolyn, Irwin, Gareth, McIntosh, Stuart A, Refsum, Sigi, Sloan, Samantha, Mallon, Peter, Sirianni, Chiara, Khattak, Ilyas, Nagachandra, Geerthan, Kiruparan, Pasupathy, Debanth, Debasish, Davey, Simon, Curran, Terry-Ann, Svenning, Matilda, Govindarajulu, Sasirekha, Rayter, Zenon, Ainsworth, Rachel, Cawthorn, Simon, Sahu, Ajay, Wilson, Sherif, Prousskaia, Elena, Accurso, Antonello, Rocco, Nicola, Di Micco, Rosa, Limite, Gennaro, Ceccarino, Raffaele, Liccardo, Raffaele, Coco, Guido, Nizamoglu, Metin, Morgan, Mary, Ramakrishnan, Venkat, Catanuto, Giuseppe, Wilkins, Alex, McManus, Penelope, Kneeshaw, Peter, Grover, Kartikae, Mahapatra, Tapan, Wooler, Brendan, Elahi, Bilal, Ihsan, Naila, Bucknor, Alexandra, Reissis, Dimitris, Hunter, Judith, Wood, Simon, Jallali, Navid, Henry, Francis P, Verjee, Liaquat S, Lee, Jason, Khan, Shazia M, Azmy, Iman, Massey, Julia, Hollywood, Ciaran, Oluwajana, Michael, Bathla, Sonia, Seward, Joanna, Harding-MacKean, Claudia, Lane, Risha, Murali, Kothandaraman, Biswas, Bashishta, Trapszo, Pawel, Seetharam, Seema, Kennedy, Katy, Alder, Louise, Graja, Tomasz, Amin, Khalid, Kokan, Jalal, Roshanlall, Chandeena, Gill, Emma, Kulkarni, Dhananjay, Dixon, JM, Young, Oliver, Saleem, Talha, Biddle, M, Kearns, Marie, Weiler-Mithoff, Eva, Chew, Ben, Malyon, Andy, Scott, John, McGill, David, Mackay, Iain, Bains, Salena, Barrows, Sara, Pilgrim, Simon, Shokuhi, Sheila, Lambert, Kelly, Kenny, Frances, Valassiadou, Kalliope, Kaushik, Monika, Krupa, Jaroslaw, Dragoumis, Dimitris, Ain, Quratul, Lampropoulos, Pavlos, Moss, Sarah, Khalil, Haitham, Haq, Anwar, Balasubramanian, Balapathiran, Charalampou-Dis, Petros, Hamed, Hisham, Kothari, Ashutosh, Kovacs, Tibor, Douek, Michael, Mehmood, Iftikhar, Ray, Biswajit, Adelekan, Matthew, Humphreys, Laura, Tayeh, Salim, Choy, Christina, Parvanta, Laila, Michieletto, Silvia, Saibene, Tania, O'Brien, James, Down, Sue, Downey, Sarah, Pereira, Jerome, Sami, AS, Gvaramadze, Anzors, Jibril, Jibril A, Thekkinkattil, Dinesh, Udayasankar, S, Khawaja, Saira, Shariaha, Yousef, Holt, Simon, James, Ruth, Rizki, Hirah, Kirkpatrick, Katharine, Ravichandran, Duraisamy, Shrestha, Deepak, Barua, Ellora, Akolekar, Deepika, Hamad, Ahmed, Kleidi, Eleftheria, Hignett, Susan, Pope, Vanessa, Naseem, Salma, Isherwood, Jennifer, Soulsby, Rachel, Taylor, Amanda, Chin, Kian, Nguyen, Dai, Guest, Francesca, Thorne, Amanda, Kirchhoff, Chris, Murphy, Declan C, Lo, Michelle, Harcourt, Ruth, Pain, Simon J, Hussien, Maged I, Zechmeister, Katalin, Sassoon, EM, Figus, Andrea, Haywood, Richard M, Ali, Rozina, Alexander, Susanna, Geropantas, Konstantinos, Epurescu, Daniel, Lewis, Rebecca, Fafemi, Oladapo, Gahir, Jasdeep, Gandamihardja, Tasha, Kelsall, Jennett, Muhibullah, Nazli, Otieno, Charlene, Mazari, Fayyaz, Dauria, Marta, Whisker, Lisa, Macmillan, Douglas, Gutteridge, Eleanor, Rasheed, Tuabin, Khout, Hazem, Asgeirsson, Kristjan, McCulley, Stephen, Mariniello, Maria Donatella, Roncella, Manuela, Ghilli, Matteo, Colizzi, Livio, Rossetti, Elena, Marzia, Lo Russo, Fustaino, Loredana, Li, Alessandro Quattrini, Harvey, Kate L, Windle, Rebecca, Remoundos, Dionysios Dennis, Roy, Pankaj, MacLean, Gael, Adwani, Asha, Popa, Elena, Goh, Steven, Shetty, Geeta, Clark, Sarah, Bernaudo, Lorenzo, Agrawal, Avi, Mansfield, Lucy, Tebbal, Sally, Patel, Ashraf, Grassi, Veronica, Pujji, Ojas, Hamnett, Kathryn, Basu, Naren, Granger, Emily, Durbar, Michael, Pikoulas, Panagiotis, Garnsey, Clare, Walker, Philip, Vollermere, Angela J, Michalakis, Ioannis, Jones, Robin, Youssef, Mina, Ives, Charlotte, Masood, Mohammad, Dunn, Julie, Olsen, Sisse, Ferguson, Douglas, Tillett, Rachel, Allan, Anna, Woollard, Alex, Canny, Rebecca, Woollard, Alexander, Mosahebi, Afshin, Hamilton, Stephen, Ghali, Shadi, Marsh, Daniel, Chana, Jagdeep, Sojitra, Nilesh, Younis, Ibby, Rainsbury, Dick, Chand, Natalie, Kalles, Vasileios, Stebbing, Anne, Harris, Kevin, Laws, Siobhan, Tansley, Anne, Mitchell, Geraldine, de Sousa, Emma, Henderson, Julia, Chandrashekar, Mysore, Pereira, Bernadette, Constantinou, Chloe, Elfadl, Dalia, Irakleidis, Foivos, Hernan, Izaro, Byrne, Miriam, To, Natalie, O'Connell, Rachel, Rusby, Jennifer, Barry, Peter, Krupa, Katerine, Allum, William, MacNeill, Fiona, Roche, Nicola, Gui, Gerald, Ramsey, Kelvin, Harris, Paul, James, Stuart, Power, Kieran, Sutton, Richard, McIntosh, Jamie, Laurence, Nicola, MacLennan, Louise, Milligan, Robert, Cain, Henry, Critchley, Adam, O'Donoghue, Joe, Kalra, Loraine, Collis, Nick, Weston-Petrides, Gina, Fiddes, Roanne, Brown, Victoria, Aertssen, Anna, Slade-Sharman, Diana, Khan, Mansoor, McGuiness, Caroline, Amorosi, Vittoria, Fabio, Santanelli di Pompeo, Exarchos, Georgios, Jiwa, Natasha, Hu, Jennifer, Ledwidge, Serena, Johnson, Laura, Peel, Anthony, Dhooma, Naseem, Farrell, Eric, Devane, Liam, Tevlin, Ruth, McDermott, Enda, Prichard, Ruth, Evoy, Denis, Rothwell, Jane, Geraghty, James, Morrison, Colin, Lawlor, Catriona, Langlands, Fiona, Taylor, Lauren, Turton, Philip, Achuthan, Raj, Horgan, Kieran, Mckenzie, Shireen, Hogan, Brian, Lansdown, Mark, Navin, Channegowda, Sherwin, Liz, Mortimer, Caroline, Garg, Neeraj, Adam, Rahma, Arif, Tahera, Kryjak, Zbigniew, Ali, Deedar, Sowdi, Ravi, Fage, Elena, Mylvaganam, Senthurun, Matey, Pilar, Vidya, Raghavan, Sircar, Tapan, Asaad, Oubida, Bhaskar, Pud, Dordea, Matei, Chrysafi, Ada, McCartan, Damian, Dave, Rajiv, Foster, Rachel, Wilson, Rebecca, Okwemba, Sylvia, Majeed, Yousef, Mathen, Vinod, Murphy, John, Barnes, Nicola, Gandhi, Ashu, Harvey, James, Kirwan, Cliona C, Johnson, Richard, Patel, Krupali, Ribas, Maria Dalmau, Vigneswaran, Natali, Challoner, Tom, Park, Alan, Rizkalla, Maged, Tomlins, Abigail, McEvoy, Kat, Jafferbhoy, Sadaf, Soumian, Soni, Narayanan, Sankaran, Kirby, Robert, Bajrusevic, Sladana, Maalo, Joseph, Charalambous, Michalis, Lai, Lee Min, Chong, Kelvin, Thomson, Simon, Monib, Sherif, Chagla, Leena, Audisio, Riccardo, Taghizadeh, Rieka, Iqbal, Azhar, James, Karen, Callaghan, Maria, Poonawala, Shabbir, Lund, Jonathan, Vinayagam, Raman, Thrush, Steven, Thomas, Rachel Bright, Mullan, Michelle, Taylor, Jevan, Yoshimura, Ryo, Mathew, Tom, Jones, Ben Mancey, Munot, Kailas, Nasr, Rana, Piper, Jenny, El-Sharief, Deena, Mustafa, Mohammed, Dumitru, Dorin, Christopoulos, Petros, O'Leary, Peter, Athanasiou, Irene, Johns, Neil, Mehta, Disha, Bibi, Saira, Syed, Farah, Koris, Jacob, Healy, Samuel, Shanks, Lindsay, Oliver, James, Bucata, Claudiu, Clarke, Natalie, Bignell, Kym, Akerlund, Malin, Brock, Lisa, Hallam, Kelly, Howes, Rachel, Armstrong, Alexander, Sethu, Claire, Zeidan, Bashar, Sjokvist, Olivia, Tasoulis, Marios, Sundaramoorthy, Souganthy, Harris, Chad, Wintrip, Dorothy, Lymperopoulos, N, Jain, Yogesh, Balata, Safa Ahmed, Grp, iBRA-2 Steering, and Collab, Breast Reconstruction Res

Subjects
Adult, Cancer Research, medicine.medical_specialty, Time Factors, medicine.medical_treatment, Mammaplasty, trainee collaboratives, Breast Neoplasms, Article, Cohort Studies, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Breast cancer, breast cancer, Adjuvant therapy, cohort study, Medicine, Humans, Prospective Studies, Prospective cohort study, Mastectomy, Aged, Cancer, Aged, 80 and over, Manchester Cancer Research Centre, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, adjuvant therapy, immediate breast reconstruction, Middle Aged, medicine.disease, Surgery, Radiation therapy, Oncology, Centre for Surgical Research, Chemotherapy, Adjuvant, Outcomes research, 030220 oncology & carcinogenesis, Surgical oncology, Female, Breast reconstruction, business, Complication, Cohort study
Abstract

Background: Immediate breast reconstruction (IBR) is routinely offered to improve quality-of-life for women requiring mastectomy, but there are concerns that more complex surgery may delay adjuvant oncological treatments and compromise long-term outcomes. High-quality evidence is lacking. The iBRA-2 study aimed to investigate the impact of IBR on time to adjuvant therapy.Methods: Consecutive women undergoing mastectomy ± IBR for breast cancer July–December, 2016 were included. Patient demographics, operative, oncological and complication data were collected. Time from last definitive cancer surgery to first adjuvant treatment for patients undergoing mastectomy ± IBR were compared and risk factors associated with delays explored.Results: A total of 2540 patients were recruited from 76 centres; 1008 (39.7%) underwent IBR (implant-only [n = 675, 26.6%]; pedicled flaps [n = 105,4.1%] and free-flaps [n = 228, 8.9%]). Complications requiring re-admission or re-operation were significantly more common in patients undergoing IBR than those receiving mastectomy. Adjuvant chemotherapy or radiotherapy was required by 1235 (48.6%) patients. No clinically significant differences were seen in time to adjuvant therapy between patient groups but major complications irrespective of surgery received were significantly associated with treatment delays.Conclusions: IBR does not result in clinically significant delays to adjuvant therapy, but post-operative complications are associated with treatment delays. Strategies to minimise complications, including careful patient selection, are required to improve outcomes for patients.

Published
2019

43. MOESM1 of miR-145 supports cancer cell survival and shows association with DDR genes, methylation pattern, and epithelial to mesenchymal transition

Author

Siddharth Manvati, Mangalhara, Kailash, Ponnuswamy Kalaiarasan, Rupali Chopra, Gaurav Agarwal, Kumar, Rakesh, Saini, Sunil, Kaushik, Monika, Ankita Arora, Kumari, Usha, Rameshwar Bamezai, and Dhar, Pawan

Abstract

Additional file 1: Table S1. Percentage methylation values of 10 CpG positions: identified to be up regulated or down regulated in association with miR-145 expression under both in-vitro (Mock, miR-145) and in-vivo (Stage 1 + 2, Stage 3 + 4, Node 0, Node 1, Node 2, Node 3) and conditions.

Published
2019
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48. REQUITE: A prospective multicentre cohort study of patients undergoing radiotherapy for breast, lung or prostate cancer

Author

Seibold, Petra, primary, Webb, Adam, additional, Aguado-Barrera, Miguel E., additional, Azria, David, additional, Bourgier, Celine, additional, Brengues, Muriel, additional, Briers, Erik, additional, Bultijnck, Renée, additional, Calvo-Crespo, Patricia, additional, Carballo, Ana, additional, Choudhury, Ananya, additional, Cicchetti, Alessandro, additional, Claßen, Johannes, additional, Delmastro, Elena, additional, Dunning, Alison M., additional, Elliott, Rebecca M., additional, Fachal, Laura, additional, Farcy-Jacquet, Marie-Pierre, additional, Gabriele, Pietro, additional, Garibaldi, Elisabetta, additional, Gómez-Caamaño, Antonio, additional, Gutiérrez-Enríquez, Sara, additional, Higginson, Daniel S., additional, Johnson, Kerstie, additional, Lobato-Busto, Ramón, additional, Mollà, Meritxell, additional, Müller, Anusha, additional, Payne, Debbie, additional, Peleteiro, Paula, additional, Post, Giselle, additional, Rancati, Tiziana, additional, Rattay, Tim, additional, Reyes, Victoria, additional, Rosenstein, Barry S., additional, De Ruysscher, Dirk, additional, De Santis, Maria Carmen, additional, Schäfer, Jörg, additional, Schnabel, Thomas, additional, Sperk, Elena, additional, Symonds, R. Paul, additional, Stobart, Hilary, additional, Taboada-Valladares, Begoña, additional, Talbot, Christopher J., additional, Valdagni, Riccardo, additional, Vega, Ana, additional, Veldeman, Liv, additional, Ward, Tim, additional, Weißenberger, Christian, additional, West, Catharine M.L., additional, Chang-Claude, Jenny, additional, Lievens, Yolande, additional, van Eijkeren, Marc, additional, Vandecasteele, Katrien, additional, Elhamin, Elhaseen, additional, Ost, Piet, additional, Fonteyne, Valérie, additional, Swimberghe, Martijn, additional, Deseyne, Pieter, additional, De Neve, Wilfried, additional, Duprez, Fréderic, additional, Mareel, Marcus, additional, Monten, Chris, additional, Van Greveling, Annick, additional, Vercauteren, Tom, additional, Paelinck, Leen, additional, Defraene, Gilles, additional, Aerts, Rita, additional, Arredouani, Soumia, additional, Lambrecht, Maarten, additional, Vanneste, Ben, additional, Draghici, Roxana, additional, Giordano, Frank, additional, Herskind, Carsten, additional, Veldwijk, Marlon, additional, Helmbold, Irmgard, additional, Giesche, Ulrich, additional, Stegmaier, Petra, additional, Weiß, Christian, additional, Blaschke, Thomas, additional, Neu, Burkhard, additional, Lozza, Laura, additional, Avuzzi, Barbara, additional, Morlino, Sara, additional, Sangalli, Claudia, additional, Franceschini, Marzia, additional, Rodriguez-Lage, Belina, additional, Fernández-Tajes, Juan, additional, Fuentes-Rios, Olivia, additional, Domínguez-Rios, Isabel, additional, Fajardo-Paneque, Irene, additional, Sosa-Fajardo, Paloma, additional, Torrado-Moya, Laura, additional, Ramos-Albiac, Mónica, additional, Giraldo, Alexandra, additional, Altabas, Manolo, additional, Piqué-Leiva, Bibiana, additional, García-Relancio, David, additional, Seoane-Ramallo, Alejandro, additional, Lavers, Samuel, additional, Wright, Simon, additional, Dobbelaere, Hannah, additional, Appleton, Donna, additional, Kaushik, Monika, additional, Kenny, Frances, additional, Khout, Hazem, additional, Krupa, Jaroslaw, additional, Lambert, Kelly V., additional, Pilgrim, Simon, additional, Shokuhi, Sheila, additional, Valassiadou, Kalliope, additional, Aznar-Garcia, Luis, additional, Boiangui, Ion, additional, Kancherla, Kiran, additional, Kent, Christopher, additional, Sampson, Kufre, additional, Osman, Ahmed, additional, Sridhar, Thiagarajan, additional, Vasanthan, Subramaniam, additional, Faivre-Finn, Corinne, additional, Harrop, Victoria, additional, Keni, Manjusha, additional, Foweraker, Karen, additional, Pascoe, Abigail, additional, Esler, Claire, additional, Stock, Richard, additional, Green, Sheryl, additional, Golchin, Ava, additional, and Li, William, additional

Published
2019
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