48 results on '"Kaufman, Joshua D."'
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2. Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions
3. Using amide (super1)H and (super15)N transverse relaxation to detect millsecond time-scale motions in perdeuterated proteins: Application to HIV-1 protease
4. Flexibility and function in HIV protease: dynamics of the HIV-1 protease bound to the asymmetric inhibitor kynostatin 272 (KNI-272)
5. Bound water molecules at the interface between the HIV-1 protease and a potent inhibitor, KNI-272, determined by NMR
6. Mapping hydration water molecules in the HIV-1 protease/DMP323 complex in solution by NMR spectroscopy
7. Solution NMR evidence that the HIV-1 protease catalytic aspartyl groups have different ionization states in the complex formed with the asymmetric drug KNI-272
8. Structures of Hepatitis B Virus Core- and e-Antigen Immune Complexes Suggest Multi-point Inhibition
9. Structure of an RNA Aptamer that Can Inhibit HIV-1 by Blocking Rev-Cognate RNA (RRE) Binding and Rev-Rev Association
10. HIV-1 gp41 transmembrane oligomerization monitored by FRET and FCS
11. Chimeric rabbit/human Fab antibodies against the hepatitis Be-antigen and their potential applications in assays, characterization, and therapy
12. Expression and Purification of ZASP Subdomains and Clinically Important Isoforms: High-Affinity Binding to G-Actin
13. Micelle-induced curvature in a water-insoluble HIV-1 env peptide revealed by NMR dipolar coupling measurement in stretched polyacrylamide gel
14. HIV-1 Envelope Protein gp41: An NMR Study of Dodecyl Phosphocholine Embedded gp41 Reveals a Dynamic Prefusion Intermediate Conformation
15. A Conserved Hydrogen-Bonding Network of P2 bis -Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV
16. Z-disc-associated, Alternatively Spliced, PDZ Motif-containing Protein (ZASP) Mutations in the Actin-binding Domain Cause Disruption of Skeletal Muscle Actin Filaments in Myofibrillar Myopathy
17. Determination of the rate of monomer interchange in a ligand-bound homodimeric protein from NOESY cross peaks: application to the HIV protease/KNI-529 complex
18. Identification and Dynamics of a Heparin-Binding Site in Hepatocyte Growth Factor †
19. Four-dimensional (super 15)N-separated NOESY of slowly tumbling perdeuterated (super 15)N-enriched proteins: application to HIV-1 nef
20. P2′ Benzene Carboxylic Acid Moiety Is Associated with Decrease in Cellular Uptake: Evaluation of Novel Nonpeptidic HIV-1 Protease Inhibitors Containing P2 bis -Tetrahydrofuran Moiety
21. Internal Dynamics of the Homotrimeric HIV-1 Viral Coat Protein gp41 on Multiple Time Scales
22. The Homotrimeric HIV-1 Viral Coat Protein GP41 is Highly Dynamic
23. NMR and X-ray evidence that the HIV protease catalytic aspartyl groups are protonated in the complex formed by the protease and a non-peptide cyclic urea-based inhibitor
24. Generation and Characterization of a Chimeric Rabbit/Human Fab for Co-Crystallization of HIV-1 Rev
25. Activator Gcn4 Employs Multiple Segments of Med15/Gal11, Including the KIX Domain, to Recruit Mediator to Target Genes in Vivo
26. Analysis and characterization of dimerization inhibition of a multi-drug-resistant Human Immunodeficiency Virus Type 1 protease using a novel size-exclusion chromatographic approach
27. Anti-HIV and anti-tumor protein MAP30, a 30 kDa single-strand type-I RIP, shares similar secondary structure and β-sheet topology with the A chain of ricin, a type-II RIP
28. Dissociation of Heparan Sulfate and Receptor Binding Domains of Hepatocyte Growth Factor Reveals That Heparan Sulfate-c-Met Interaction Facilitates Signaling
29. Identification and Dynamics of a Heparin-Binding Site in Hepatocyte Growth Factor
30. Separation and crystallization ofT= 3 andT= 4 icosahedral complexes of the hepatitis B virus core protein
31. Using Amide 1H and 15N Transverse Relaxation To Detect Millisecond Time-Scale Motions in Perdeuterated Proteins: Application to HIV-1 Protease
32. Molecular Cloning and Characterization of a Transcription Regulator with Homology to GC-binding Factor
33. The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site
34. Functional and biophysical characterization of recombinant human hepatocyte growth factor isoforms produced in Escherichia coli
35. Solution NMR Evidence That the HIV-1 Protease Catalytic Aspartyl Groups Have Different Ionization States in the Complex Formed with the Asymmetric Drug KNI-272
36. Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy
37. Four-Dimensional 15N-Separated NOESY of Slowly Tumbling Perdeuterated 15N-Enriched Proteins. Application to HIV-1 Nef
38. Flexibility and function in HIV-1 protease
39. Secondary structure and signal assignments of human‐immunodeficiency‐virus‐1 protease complexed to a novel, structure‐based inhibitor
40. Construction of an enzymatically active ribonuclease H domain of human immunodeficiency virus type 1 reverse transcriptase
41. Anti-HIV and anti-tumor protein MAP30, a 30 kDa single-strand type-I RIP, shares similar secondary structure and ²-sheet topology with the A chain of ricin, a type-II RIP.
42. Separation and crystallization of T = 3 and T = 4 icosahedral complexes of the hepatitis B virus core protein.
43. Solution Structure of Anti-HIV-1 and Anti-Tumor Protein MAP30 Structural Insights into Its Multiple Functions
44. Separation and crystallization of T= 3 and T= 4 icosahedral complexes of the hepatitis B virus core protein
45. Flexibility and function in HIV-1 protease
46. Chimeric rabbit/human Fab antibodies against the hepatitis B e-antigen and their potential applications in assays, characterization, and therapy.
47. Z-disc-associated, Alternatively Spliced, PDZ Motif-containing Protein (ZASP) Mutations in the Actin-binding Domain Cause Disruption of Skeletal Muscle Actin Filaments in Myofibrillar Myopathy.
48. Expression and Purification of ZASP Subdomains and Clinically Important Isoforms: High-Affinity Binding to G-Actin
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