Search

Your search keyword '"Katz-Salamon M"' showing total 173 results
Start Over Author "Katz-Salamon M"
173 results on '"Katz-Salamon M"'

4. Delayed chemoreceptor responses in infants with apnoea

Author

Katz-Salamon, M.

Subjects
Chemoreceptors -- Health aspects -- Research, Infants -- Health aspects -- Research, Chemical senses -- Health aspects -- Research, Apnea -- Causes of -- Research -- Care and treatment, Family and marriage, Health, Care and treatment, Research, Causes of, Health aspects
Abstract

Aims: To test the hypothesis that apnoea of infancy (AOI) is due to a deficit in chemoreception. Methods: Tests were performed on 112 infants: 43 healthy control infants, 28 infants [...]

Published
2004

12. Adverse circulatory effects of passive smoking during infancy: surprisingly strong, manifest early, easily avoided

Author

Cohen, G. Vardavas, C. Patelarou, E. Kogevinas, M. and Katz-Salamon, M.

Abstract

AimTo compare blood pressure reactions (BPR) of infants to mild stress for evidence of adverse cardiovascular effects of passive exposure to tobacco smoke during pregnancy and early infancy. MethodsAn observational field study conducted in Crete. We compared 4- to 6-month olds of lifelong nonsmokers minimally (controls, n=9) or frequently exposed to tobacco smoke (passive smokers; n=10) with those born to habitual smokers (n=6). Smoke exposure was verified biochemically (urine cotinine each trimester and at study). We recorded beat-to-beat blood pressure (BP) during brief repositioning manoeuvres performed during a daytime nap and analysed BPR (% change in BP during head-up tilt) for associations with maternal and infant cotinine. ResultsWe observed a 20-fold difference between BPR of infants of controls versus passive smokers - exceptional given number of infants ( error/confidence level 90%). The BPR declined linearly as the infant’s (but not mother’s) cotinine level rose (p=0.04), indicating abnormal BPR was caused mainly by postnatal smoke exposure. Infants of active smokers differed from those of passive smokers. ConclusionCardiovascular effects of passive smoking by a newborn infant manifest early on and are exceptionally strong. They can be largely avoided by keeping the home smoke rigorously free.

Published
2014

16. Abnormal heart rate response to hypercapnia in boys with an apparent life-threatening event.

Author

Edner, A, Ericson, Mats, Milerad, J, Katz-Salamon, M, Edner, A, Ericson, Mats, Milerad, J, and Katz-Salamon, M

Abstract

AIM: To determine instantaneous cardiac variability responses to increased carbon dioxide (CO2) during quiet sleep in infants who may be at risk for the Sudden Infant Death syndrome (SIDS). METHODS: The cardiac rate variability before, during and after a CO2 challenge was examined in 41 infants who had experienced an apparent life-threatening event (ALTE) and 41 gender- and age-matched control infants. RESULTS: The ALTE infants responded to CO2 breathing with a significant increase in R-R intervals, i.e. decreases in heart rate, compared to the controls (45.1% increase in R-R intervals vs. 41.4%; p = 0.005). The differences between ALTE infants and controls depended primarily on the boys' responses. CONCLUSION: ALTE infants, particularly ALTE boys, have an autonomic dysfunction-lower sympathetic stimulation and/or inhibited vagal withdrawal when stressed with CO2. The outcome might provide clues to the mechanisms underlying the cardiovascular processes contributing to the terminal event in SIDS., NR 20140805

Published
2002
Full Text
View/download PDF

18. Heart rate variability in infants with apparent life-threatening events.

Author

Edner, A, Katz-Salamon, M, Lagercrantz, H, Ericson, Mats, Milerad, J, Edner, A, Katz-Salamon, M, Lagercrantz, H, Ericson, Mats, and Milerad, J

Abstract

Heart rate variability (HRV) is often used as an index of sympatho-vagal balance. A decreased HRV has been observed in patients with central hypoventilation and in infants who have later succumbed to sudden infant death syndrome (SIDS). The aim of the present study was to investigate whether HRV is altered in infants with apparent life-threatening events (ALTE), a group with an increased risk of SIDS. Fifty infants with ALTE were compared with 50 age- and sex-matched controls. ECG was recorded overnight in all infants. Two sequences of RR intervals free of artefacts were selected from each sleep state and spectral analysis of RR variability was performed. The mean and SD of RR and the low (LFPow) and high (HFPow) frequency power were analysed. In active sleep (AS) the LF/HF ratio was lower in ALTE infants, but no differences were seen in either the LFPow or the HFPow. In quiet sleep (QS), however, ALTE infants had higher SD-RR (p = 0.006), greater HFPow (p = 0.02) and VLFPow (very low frequency power, p = 0.02) than the control infants. The same results were seen when the two sleep states were combined for analysis, ALTE infants had higher SD-RR (p = 0.004), HFPow (p = 0.006) and VLFPow (p = 0.04). Conclusion: The different HRV pattern in ALTE infants compared to healthy controls suggests an altered autonomic control., NR 20140805

Published
2000
Full Text
View/download PDF

42. Increased inspiratory effort in infants with a history of apparent life-threatening event.

Author

Horemuzova, E, Katz-Salamon, M, and Milerad, J

Subjects
*SUDDEN infant death syndrome, *SLEEP physiology, *RESPIRATION
Abstract

Unlabelled: The objective of this study was to compare the results of polysomnography between infants with a history of apparent life-threatening event (ALTE) and controls. In this case-control study, 40 full-term ALTE infants, aged 2-36 wk at the time of the event, were compared with 40 age- and sex-matched randomly selected controls. SaO2, tcpO2, tcpCO2, heart rate (HR), vector of rib cage and abdominal respiratory movements (phase angle, as an index of inspiratory effort) were recorded during natural nocturnal active and quiet sleep (AS, QS). SaO2, tcpO2, tcpCO2 were similar in ALTE and controls in both sleep states. Phase angle was increased in ALTE infants in both AS (59+/-46 vs 26+/-17 degrees) and QS (53+/-46 vs 18+/-14, p < 0.001). Eleven ALTE infants (27.5%) experienced SaO2 < 90%, with a mean decrease in SaO2 to 86+/-1.6% (mean +/- SD), compared with 10% for controls (p=0.003). In eight ALTE infants, SaO2 values <90% were linked to thoracoabdominal asynchrony. SaO2 < 90% in conjunction with HR <100 bpm were detected in three ALTE infants and one control. Periodic breathing was observed in 45% of ALTE infants and 40% of controls.Conclusion: The mean values of oxygen saturation, tcpO2 and carbon dioxide levels in ALTE infants are comparable with those of healthy controls but the ALTE infants exhibit more hypoxaemic episodes and increased inspiratory effort during sleep. [ABSTRACT FROM AUTHOR]

Published
2002
Full Text
View/download PDF

44. CO2-Sensitivity in Newborn and Young Infants Tested by the Rebreathing Method

Author

Katz-Salamon, M.-S., Hertzberg, T., and Lagercrantz, H.

Abstract

The rebreathing method in newborn and young infants was tested with regard to the effects of increasing levels of CO2 on the behavioral state and to the influence of facial stimulation caused by the use of a face mask and pneumotachograph on the breathing pattern. Successive increases in inspired CO2 levels from 3 to 8.5% did not change the behavioral state. The application or removal of a face mask, with or without an attached pneumotachograph, caused an immediate disruption in the breathing pattern which lasted 10–40 s. Thereafter, breathing stabilized. When only the face mask was used, the increases in minute ventilation, tidal volume and cycle duration of 7, 13 and 5 %, respectively, were transient and lasted for 40–50 breaths. The breathing then returned to control levels. In contrast, breathing through the face mask connected to the pneumotachograph caused a long-lasting increase in ventilation (12%) due to the retention of CO2 in the spirometric circuit. We conclude that the inhalation of a continuously increasing mixture of 3–8.5% CO2 in O2 did not influence the behavioral state and that the effect of face mask on breathing pattern was transient.

Published
1991
Full Text
View/download PDF

45. [23 physicians comments on circumcision of small boys: The Swedish Medical Association should take a more humble approach]

Author

Altman, M., Altman, D., Fischler, B., Björkstén, B., Bruchfeld, A., Böhm, F., Cecilia Chrapkowska, Finder, M., Finkel, Y., Halmin, M., Heyman, M., Ilicki, A., Kahn, R., Karpman, D., Katz-Salamon, M., Lagercrantz, H., Mårtensson, T., Nisell, H., Rosling, H., Sarman, I., Wackernagel, D., Wennergren, G., and Wilczek, M.

Subjects
Male, Sweden, Ethics Committees, Circumcision, Male, Religion and Medicine, Judaism, Humans, Islam, Societies, Medical

46. Glial fibrillary acidic protein is increased in the cerebrospinal fluid of preterm infants with abnormal neurological findings

Author

Henrik Hagberg, Hugo Lagercrantz, Lars Rosengren, Jonsson S, Hans Forssberg, Hesser U, Katz-Salamon M, and Mats Blennow

Subjects
Male, medicine.medical_specialty, Developmental Disabilities, Glutamic Acid, Gestational Age, macromolecular substances, Neurological disorder, Brain damage, Infant, Premature, Diseases, Central nervous system disease, Norepinephrine, Cerebrospinal fluid, Predictive Value of Tests, Internal medicine, Glial Fibrillary Acidic Protein, medicine, Humans, Hypoxanthine, Glial fibrillary acidic protein, biology, Psychomotor retardation, business.industry, Postmenstrual Age, Glutamate receptor, Infant, Newborn, General Medicine, medicine.disease, Surgery, Endocrinology, nervous system, Case-Control Studies, Hypoxanthines, Pediatrics, Perinatology and Child Health, biology.protein, Brain Damage, Chronic, Female, medicine.symptom, business, Biomarkers
Abstract

Glial fibrillary acidic protein (GFAP) is the structural protein of the intermediate filament of astroglia. The aims of the present study were to examine GFAP in the cerebrospinal fluid (CSF) of preterm infants at different postmenstrual ages and to evaluate the potential of GFAP to predict abnormal neurodevelopmental outcome. GFAP increased in correlation with postmenstrual age in preterm infants (n = 17) and full-term infants (n = 9). The levels were five times higher in preterm infants (n = 10) with an abnormal neonatal course and/or an abnormal neurological outcome than in healthy preterm infants. The positive predictive value of a GFAP higher than the 98th percentile of normal infants was 69%, while a GFAP level below this limit invariable predicted a good outcome. Simultaneously analysed noradrenaline, hypoxanthine and glutamate did not differ between the groups. We conclude that CSF GFAP increases with maturity and that CSF GFAP appears to be a promising marker for perinatal brain damage.

47. [23 physicians comments on circumcision of small boys: The Swedish Medical Association should take a more humble approach]. | 23 läkare om omskärelse av små pojkar: Läkarförbundet bör inta en mer odmjuk hållning

Author

Altman, M., Altman, D., Fischler, B., Björkstén, B., Bruchfeld, A., Böhm, F., Chrapkowska, C., Finder, M., Finkel, Y., Halmin, M., Heyman, M., Ilicki, A., Kahn, R., Karpman, D., Katz-Salamon, M., Lagercrantz, H., Mårtensson, T., Nisell, H., Rosling, H., Sarman, I., Dirk Wackernagel, Wennergren, G., and Wilczek, M.

50. Guidelines for diagnosis and management of congenital central hypoventilation syndrome.

Author

Trang H, Samuels M, Ceccherini I, Frerick M, Garcia-Teresa MA, Peters J, Schoeber J, Migdal M, Markstrom A, Ottonello G, Piumelli R, Estevao MH, Senecic-Cala I, Gnidovec-Strazisar B, Pfleger A, Porto-Abal R, and Katz-Salamon M

Subjects
Adult, Child, Homeodomain Proteins genetics, Humans, Hypoventilation diagnosis, Hypoventilation genetics, Hypoventilation therapy, Mutation, Transcription Factors genetics, Hypoventilation congenital, Sleep Apnea, Central diagnosis, Sleep Apnea, Central genetics, Sleep Apnea, Central therapy
Abstract

Background: Congenital Central Hypoventilation Syndrome (CCHS) is a rare condition characterized by an alveolar hypoventilation due to a deficient autonomic central control of ventilation and a global autonomic dysfunction. Paired-like homeobox 2B (PHOX2B) mutations are found in most of the patients with CCHS. In recent years, the condition has evolved from a life-threatening neonatal onset disorder to include broader and milder clinical presentations, affecting children, adults and families. Genes other than PHOX2B have been found responsible for CCHS in rare cases and there are as yet other unknown genes that may account for the disease. At present, management relies on lifelong ventilatory support and close follow up of dysautonomic progression. BODY: This paper provides a state-of-the-art comprehensive description of CCHS and of the components of diagnostic evaluation and multi-disciplinary management, as well as considerations for future research., Conclusion: Awareness and knowledge of the diagnosis and management of this rare disease should be brought to a large health community including adult physicians and health carers.

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results